ABIN1724714

antibody from antibodies-online

Targeting: CHEK2 bA444G7, CDS1, CHK2, HuCds1, PP1425, RAD53

Western blot (Supportive data in Antibodypedia)

ELISA (Recommended by provider)

Immunocytochemistry (Supportive data in Antibodypedia)

Immunohistochemistry (Supportive data in Antibodypedia)

Antibody Data

Product number

ABIN1724714

Provider

antibodies-online

Product name

anti-Checkpoint Kinase 2 (CHEK2) (AA 481-531) antibody

Antibody type

Monoclonal

Reactivity

Human

Host

Mouse

Epitope

AA 481-531

Isotype

IgG

Antibody clone number

1C12B8

Vial size

100 μL

Storage

4°C, -20°C for long term storage

References

Submitted references

Constitutional CHEK2 mutations are associated with a decreased risk of lung and laryngeal cancers.

Cybulski C, Masojc B, Oszutowska D, Jaworowska E, Grodzki T, Waloszczyk P, Serwatowski P, Pankowski J, Huzarski T, Byrski T, Górski B, Jakubowska A, Debniak T, Wokolorczyk D, Gronwald J, Tarnowska C, Serrano-Fernández P, Lubinski J, Narod SA
Carcinogenesis 2008 Apr;29(4):762-5

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CHK2 kinase: cancer susceptibility and cancer therapy - two sides of the same coin?

Antoni L, Sodha N, Collins I, Garrett MD
Nature reviews. Cancer 2007 Dec;7(12):925-36

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Genetic and functional analysis of CHEK2 (CHK2) variants in multiethnic cohorts.

Bell DW, Kim SH, Godwin AK, Schiripo TA, Harris PL, Haserlat SM, Wahrer DC, Haiman CA, Daly MB, Niendorf KB, Smith MR, Sgroi DC, Garber JE, Olopade OI, Le Marchand L, Henderson BE, Altshuler D, Haber DA, Freedman ML
International journal of cancer 2007 Dec 15;121(12):2661-7

Western blot

Supportive validation

Submitted by

antibodies-online (provider)

Main image

Experimental details

WB

Immunocytochemistry

Supportive validation

Submitted by

antibodies-online (provider)

Main image

Experimental details

ICC

Immunohistochemistry

Supportive validation

Submitted by

antibodies-online (provider)

Main image

Experimental details

IHC