PAB5293

antibody from Abnova Corporation

Targeting: CHEK2 bA444G7, CDS1, CHK2, HuCds1, PP1425, RAD53

Western blot (Supportive data in Antibodypedia)

Immunohistochemistry (Supportive data in Antibodypedia)

Antibody Data

Product number

PAB5293

Provider

Abnova Corporation

Proper citation

Abnova Corporation Cat#PAB5293, RRID:AB_1573964

Product name

CHEK2 polyclonal antibody

Antibody type

Polyclonal

Description

Rabbit polyclonal antibody raised against synthetic peptide of CHEK2.

Storage

Store at -20°C.Aliquot to avoid repeated freezing and thawing.

References

Submitted references

ATM-dependent phosphorylation of ATF2 is required for the DNA damage response.

Bhoumik A, Takahashi S, Breitweiser W, Shiloh Y, Jones N, Ronai Z
Molecular cell 2005 May 27;18(5):577-87

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Conserved modes of recruitment of ATM, ATR and DNA-PKcs to sites of DNA damage.

Falck J, Coates J, Jackson SP
Nature 2005 Mar 31;434(7033):605-11

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Activation of the DNA damage checkpoint and genomic instability in human precancerous lesions.

Gorgoulis VG, Vassiliou LV, Karakaidos P, Zacharatos P, Kotsinas A, Liloglou T, Venere M, Ditullio RA Jr, Kastrinakis NG, Levy B, Kletsas D, Yoneta A, Herlyn M, Kittas C, Halazonetis TD
Nature 2005 Apr 14;434(7035):907-13

Western blot

Supportive validation

Submitted by

Abnova Corporation (provider)

Main image

Experimental details

Western blot analysis of the extracts from Jurkat cells using CHEK2 polyclonal antibody (Cat # PAB5293) .

Immunohistochemistry

Supportive validation

Submitted by

Abnova Corporation (provider)

Main image

Experimental details

Immunohistochemical analysis of paraffin-embedded human breast carcinoma tissue using CHEK2 polyclonal antibody (Cat # PAB5293) .

Validation comment

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)