PAB17002

antibody from Abnova Corporation

Targeting: CHEK2 bA444G7, CDS1, CHK2, HuCds1, PP1425, RAD53

Immunohistochemistry (Supportive data in Antibodypedia)

Antibody Data

Product number

PAB17002

Provider

Abnova Corporation

Proper citation

Abnova Corporation Cat#PAB17002, RRID:AB_10616174

Product name

CHEK2 polyclonal antibody

Antibody type

Polyclonal

Description

Rabbit polyclonal antibody raised against synthetic peptide of CHEK2.

Storage

Store at 4°C for three months. For long term storage store at -20°C.Aliquot to avoid repeated freezing and thawing.

References

Submitted references

Autophosphorylated residues involved in the regulation of human chk2 in vitro.

Gabant G, Lorphelin A, Nozerand N, Marchetti C, Bellanger L, Dedieu A, Quéméneur E, Alpha-Bazin B
Journal of molecular biology 2008 Jul 11;380(3):489-503

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Human T-cell leukemia virus type 1 Tax oncoprotein prevents DNA damage-induced chromatin egress of hyperphosphorylated Chk2.

Gupta SK, Guo X, Durkin SS, Fryrear KF, Ward MD, Semmes OJ
The Journal of biological chemistry 2007 Oct 5;282(40):29431-40

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The Wip1 phosphatase (PPM1D) antagonizes activation of the Chk2 tumour suppressor kinase.

Oliva-Trastoy M, Berthonaud V, Chevalier A, Ducrot C, Marsolier-Kergoat MC, Mann C, Leteurtre F
Oncogene 2007 Mar 1;26(10):1449-58

Immunohistochemistry

Supportive validation

Submitted by

Abnova Corporation (provider)

Main image

Experimental details

Immunohistochemical analysis of paraffin-embedded human lung adenocarcinoma tissue using CHEK2 polyclonal antibody (Cat # PAB17002).

Validation comment

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)