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LearnABIN302248
antibody from antibodies-online
Targeting: CHEK2
bA444G7, CDS1, CHK2, HuCds1, PP1425, RAD53
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ImmunohistochemistryAntibody data
- Antibody Data
- Antigen structure
- References [6]
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- Validations
- Immunohistochemistry [1]
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- Product number
- ABIN302248 - Provider product page
- Provider
- antibodies-online
- Product name
- anti-Checkpoint Kinase 2 (CHEK2) antibody
- Antibody type
- Monoclonal
- Description
- Protein G Chromatography
- Reactivity
- Human
- Host
- Mouse
- Isotype
- IgG
- Antibody clone number
- 73C175-1-1
- Vial size
- 50 μg
- Storage
- Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C to -70°C forlonger. Avoid repeated freezing and thawing.Shelf life: one year from despatch.
Submitted references Reduced expression and impaired kinase activity of a Chk2 mutant identified in human lung cancer.
DNA damage-activated kinase Chk2 is independent of proliferation or differentiation yet correlates with tissue biology.
The ATM-Chk2-Cdc25A checkpoint pathway guards against radioresistant DNA synthesis.
DNA damage-induced activation of p53 by the checkpoint kinase Chk2.
The human homologs of checkpoint kinases Chk1 and Cds1 (Chk2) phosphorylate p53 at multiple DNA damage-inducible sites.
Linkage of ATM to cell cycle regulation by the Chk2 protein kinase.
Matsuoka S, Nakagawa T, Masuda A, Haruki N, Elledge SJ, Takahashi T
Cancer research 2001 Jul 15;61(14):5362-5
Cancer research 2001 Jul 15;61(14):5362-5
DNA damage-activated kinase Chk2 is independent of proliferation or differentiation yet correlates with tissue biology.
Lukas C, Bartkova J, Latella L, Falck J, Mailand N, Schroeder T, Sehested M, Lukas J, Bartek J
Cancer research 2001 Jul 1;61(13):4990-3
Cancer research 2001 Jul 1;61(13):4990-3
The ATM-Chk2-Cdc25A checkpoint pathway guards against radioresistant DNA synthesis.
Falck J, Mailand N, Syljuåsen RG, Bartek J, Lukas J
Nature 2001 Apr 12;410(6830):842-7
Nature 2001 Apr 12;410(6830):842-7
DNA damage-induced activation of p53 by the checkpoint kinase Chk2.
Hirao A, Kong YY, Matsuoka S, Wakeham A, Ruland J, Yoshida H, Liu D, Elledge SJ, Mak TW
Science (New York, N.Y.) 2000 Mar 10;287(5459):1824-7
Science (New York, N.Y.) 2000 Mar 10;287(5459):1824-7
The human homologs of checkpoint kinases Chk1 and Cds1 (Chk2) phosphorylate p53 at multiple DNA damage-inducible sites.
Shieh SY, Ahn J, Tamai K, Taya Y, Prives C
Genes & development 2000 Feb 1;14(3):289-300
Genes & development 2000 Feb 1;14(3):289-300
Linkage of ATM to cell cycle regulation by the Chk2 protein kinase.
Matsuoka S, Huang M, Elledge SJ
Science (New York, N.Y.) 1998 Dec 4;282(5395):1893-7
Science (New York, N.Y.) 1998 Dec 4;282(5395):1893-7
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