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LearnABIN343395
antibody from antibodies-online
Targeting: CHEK2
bA444G7, CDS1, CHK2, HuCds1, PP1425, RAD53
Western blotAntibody data
- Antibody Data
- Antigen structure
- References [3]
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- Validations [0]
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- Product number
- ABIN343395 - Provider product page
- Provider
- antibodies-online
- Proper citation
- Antibodies-Online Cat#ABIN343395, RRID:AB_10786811
- Product name
- anti-Checkpoint Kinase 2 (CHEK2) antibody
- Antibody type
- Polyclonal
- Antigen
- A synthetic peptide corresponding to a sequence at the C-terminal of human CHK2, different to the related rat sequence by a single amino acid.
- Description
- Affinity-purified
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Isotype
- IgG
- Vial size
- 100 μg
- Storage
- -20°C
Submitted references Phosphorylation of threonine 68 promotes oligomerization and autophosphorylation of the Chk2 protein kinase via the forkhead-associated domain.
hCds1-mediated phosphorylation of BRCA1 regulates the DNA damage response.
Heterozygous germ line hCHK2 mutations in Li-Fraumeni syndrome.
Ahn JY, Li X, Davis HL, Canman CE
The Journal of biological chemistry 2002 May 31;277(22):19389-95
The Journal of biological chemistry 2002 May 31;277(22):19389-95
hCds1-mediated phosphorylation of BRCA1 regulates the DNA damage response.
Lee JS, Collins KM, Brown AL, Lee CH, Chung JH
Nature 2000 Mar 9;404(6774):201-4
Nature 2000 Mar 9;404(6774):201-4
Heterozygous germ line hCHK2 mutations in Li-Fraumeni syndrome.
Bell DW, Varley JM, Szydlo TE, Kang DH, Wahrer DC, Shannon KE, Lubratovich M, Verselis SJ, Isselbacher KJ, Fraumeni JF, Birch JM, Li FP, Garber JE, Haber DA
Science (New York, N.Y.) 1999 Dec 24;286(5449):2528-31
Science (New York, N.Y.) 1999 Dec 24;286(5449):2528-31
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