ABIN117975
antibody from antibodies-online
Targeting: CHEK2
bA444G7, CDS1, CHK2, HuCds1, PP1425, RAD53
Antibody data
- Antibody Data
- Antigen structure
- References [3]
- Comments [0]
- Validations [0]
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- Product number
- ABIN117975 - Provider product page
- Provider
- antibodies-online
- Product name
- anti-Checkpoint Kinase 2 (CHEK2) (AA 64-73), (pThr68) antibody
- Antibody type
- Polyclonal
- Antigen
- This affinity purified antibody was prepared from whole rabbit serum produced by repeated immunizations with a synthetic peptide corresponding aa 64-73 of Human CHK2.
- Description
- Immunoaffinity chromatography.
- Reactivity
- Human
- Host
- Rabbit
- Antigen sequence
Human CHK2, 543 aa, predicted MW 60
.9 kDa 1 msresdveaq qshgssacsq phgs
vtqsqg sssqsqgiss sststmpnss qsshss
sgtl 61 ssletvstqe lysipedqep edqep
eeptp apwarlwalq dgfanlecvn dnywfgr
dks 121 ceycfdepll krtdkyrtys kkhfr
ifrev gpknsyiayi edhsgngtfv ntelvgk
gkr 181 rplnnnseia lslsrnkvfv ffdlt
vddqs vypkalrdey imsktlgsga cgevkla
fer 241 ktckkvaiki iskrkfaigs aread
palnv eteieilkkl nhpciikikn ffdaedy
yiv 301 lelmeggelf dkvvgnkrlk eatck
lyfyq mllavqylhe ngiihrdlkp envllss
qee 361 dclikitdfg hskilgetsl mrtlc
gtpty lapevlvsvg tagynravdc wslgvil
fic 421 lsgyppfseh rtqvslkdqi tsgky
nfipe vwaevsekal dlvkkllvvd pkarftt
eea 481 lrhpwlqded mkrkfqdlls eenes
talpq vlaqpstsrk rpregeaega ettkrpa
vca 541 avl- Epitope
- AA 64-73,pThr68
- Vial size
- 0.1 mg
- Concentration
- 1.0 mg/mL (by UV absorbance at 280 nm)
- Storage
- Store undiluted at 2-8°C. DO NOT FREEZE!
- Handling
- This product is photosensitive and should be protected from light
Submitted references A human Cds1-related kinase that functions downstream of ATM protein in the cellular response to DNA damage.
A human homologue of the checkpoint kinase Cds1 directly inhibits Cdc25 phosphatase.
Linkage of ATM to cell cycle regulation by the Chk2 protein kinase.
Brown AL, Lee CH, Schwarz JK, Mitiku N, Piwnica-Worms H, Chung JH
Proceedings of the National Academy of Sciences of the United States of America 1999 Mar 30;96(7):3745-50
Proceedings of the National Academy of Sciences of the United States of America 1999 Mar 30;96(7):3745-50
A human homologue of the checkpoint kinase Cds1 directly inhibits Cdc25 phosphatase.
Blasina A, de Weyer IV, Laus MC, Luyten WH, Parker AE, McGowan CH
Current biology : CB 1999 Jan 14;9(1):1-10
Current biology : CB 1999 Jan 14;9(1):1-10
Linkage of ATM to cell cycle regulation by the Chk2 protein kinase.
Matsuoka S, Huang M, Elledge SJ
Science (New York, N.Y.) 1998 Dec 4;282(5395):1893-7
Science (New York, N.Y.) 1998 Dec 4;282(5395):1893-7
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