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LearnABIN196867
antibody from antibodies-online
Targeting: CHEK2
bA444G7, CDS1, CHK2, HuCds1, PP1425, RAD53
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- Antibody Data
- Antigen structure
- References [3]
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- Product number
- ABIN196867 - Provider product page
- Provider
- antibodies-online
- Product name
- anti-Checkpoint Kinase 2 (CHEK2) (pSer516) antibody
- Antibody type
- Polyclonal
- Description
- Immunoaffinity chromatography.
- Reactivity
- Human
- Host
- Rabbit
- Epitope
- pSer516
- Vial size
- 50 μL
- Storage
- Store the antibody (in aliquots) at -20°C.
- Handling
- Avoid repeated freezing and thawing.
Submitted references Autophosphorylation of checkpoint kinase 2 at serine 516 is required for radiation-induced apoptosis.
Regulation of the Chk2 protein kinase by oligomerization-mediated cis- and trans-phosphorylation.
MDC1 is coupled to activated CHK2 in mammalian DNA damage response pathways.
Wu X, Chen J
The Journal of biological chemistry 2003 Sep 19;278(38):36163-8
The Journal of biological chemistry 2003 Sep 19;278(38):36163-8
Regulation of the Chk2 protein kinase by oligomerization-mediated cis- and trans-phosphorylation.
Schwarz JK, Lovly CM, Piwnica-Worms H
Molecular cancer research : MCR 2003 Jun;1(8):598-609
Molecular cancer research : MCR 2003 Jun;1(8):598-609
MDC1 is coupled to activated CHK2 in mammalian DNA damage response pathways.
Lou Z, Minter-Dykhouse K, Wu X, Chen J
Nature 2003 Feb 27;421(6926):957-61
Nature 2003 Feb 27;421(6926):957-61
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