ABIN393759
antibody from antibodies-online
Targeting: CHEK2
bA444G7, CDS1, CHK2, HuCds1, PP1425, RAD53
Antibody data
- Antibody Data
- Antigen structure
- References [5]
- Comments [0]
- Validations
- Western blot [4]
- ELISA [1]
- Immunohistochemistry [1]
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- Product number
- ABIN393759 - Provider product page
- Provider
- antibodies-online
- Product name
- anti-Checkpoint Kinase 2 (CHEK2) (AA 1-544) antibody
- Antibody type
- Monoclonal
- Description
- This antibody is purified through a protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS.
- Reactivity
- Human
- Host
- Mouse
- Epitope
- AA 1-544
- Isotype
- IgG
- Antibody clone number
- 4B7
- Vial size
- 100 μg
- Storage
- Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles
Submitted references Comprehensive screen of genetic variation in DNA repair pathway genes and postmenopausal breast cancer risk.
A large-scale candidate gene approach identifies SNPs in SOD2 and IL13 as predictive markers of response to preoperative chemoradiation in rectal cancer.
BRCA1, BRCA2 and CHEK2 c.1100 delC mutations in patients with double primaries of the breasts and/or ovaries.
Evaluation of the contribution of the three breast cancer susceptibility genes CHEK2, STK11, and PALB2 in non-BRCA1/2 French Canadian families with high risk of breast cancer.
CHEK2 I157T and colorectal cancer in Bulgaria.
Monsees GM, Kraft P, Chanock SJ, Hunter DJ, Han J
Breast cancer research and treatment 2011 Jan;125(1):207-14
Breast cancer research and treatment 2011 Jan;125(1):207-14
A large-scale candidate gene approach identifies SNPs in SOD2 and IL13 as predictive markers of response to preoperative chemoradiation in rectal cancer.
Ho-Pun-Cheung A, Assenat E, Bascoul-Mollevi C, Bibeau F, Boissière-Michot F, Thezenas S, Cellier D, Azria D, Rouanet P, Senesse P, Ychou M, Lopez-Crapez E
The pharmacogenomics journal 2011 Dec;11(6):437-43
The pharmacogenomics journal 2011 Dec;11(6):437-43
BRCA1, BRCA2 and CHEK2 c.1100 delC mutations in patients with double primaries of the breasts and/or ovaries.
Evans DG, Ahmed M, Bayliss S, Howard E, Lalloo F, Wallace A
Journal of medical genetics 2010 Aug;47(8):561-6
Journal of medical genetics 2010 Aug;47(8):561-6
Evaluation of the contribution of the three breast cancer susceptibility genes CHEK2, STK11, and PALB2 in non-BRCA1/2 French Canadian families with high risk of breast cancer.
Guénard F, Pedneault CS, Ouellette G, Labrie Y, Simard J, INHERIT., Durocher F
Genetic testing and molecular biomarkers 2010 Aug;14(4):515-26
Genetic testing and molecular biomarkers 2010 Aug;14(4):515-26
CHEK2 I157T and colorectal cancer in Bulgaria.
Konstantinova D, Kadiyska T, Sokolova V, Kaneva R, Mirchev M, Savov A, Aleksandrova A, Nedin D, Kostadinov E, Damyanov D, Kremensky I, Mitev V
Journal of B.U.ON. : official journal of the Balkan Union of Oncology 2010 Apr-Jun;15(2):314-7
Journal of B.U.ON. : official journal of the Balkan Union of Oncology 2010 Apr-Jun;15(2):314-7
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Supportive validation
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- ELISA
Supportive validation
- Submitted by
- antibodies-online (provider)
- Main image
- Experimental details
- IHC