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Learn29012-1-AP
antibody from Proteintech Group
Targeting: CHEK2
bA444G7, CDS1, CHK2, HuCds1, PP1425, RAD53
Western blotAntibody data
- Antibody Data
- Antigen structure
- References [12]
- Comments [0]
- Validations [0]
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- Product number
- 29012-1-AP - Provider product page
- Provider
- Proteintech Group
- Product name
- Phospho-CHEK2 (Thr68) antibody
- Antibody type
- Polyclonal
- Description
- Phospho-CHEK2 (Thr68) antibody (Cat. #29012-1-AP) is a rabbit polyclonal antibody that shows reactivity with Human and has been validated for the following applications: WB,ELISA.
- Reactivity
- Human
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 100ul
Submitted references Synergistic effects of retinol and retinyl palmitate in alleviating UVB-induced DNA damage and promoting the homologous recombination repair in keratinocytes.
Investigating the effects of miR-526b and miR-655 on doxorubicin sensitivity in breast cancer.
Distinct Oxidative Stress Adaptations Driven by the Overexpression of miR-526b, miR-655, and COX-2 in Breast Cancer.
A novel non-nad-based PARP1 inhibitor, Japoflavone B, triggered Caspase-3/GSDME-mediated pyroptosis through ROS/p38/p53 pathway in NSCLC.
Olaparib synergy screen reveals Exemestane induces replication stress in triple-negative breast cancer.
Synergistic antitumor effects and mechanistic insight of hypericin-mediated photodynamic therapy combined with Olaparib in MCF-7 BRCA1 wild-type breast cancer cells.
Kaempferol Induces DNA Damage in Colorectal Cancer Cells by Regulating the MiR-195/miR-497-PFKFB4-Mediated Nonoxidative Pentose Phosphate Pathway.
Nanoengineered Gallium Ion Incorporated Formulation for Safe and Efficient Reversal of PARP Inhibition and Platinum Resistance in Ovarian Cancer.
PI3K/mTOR inhibitors promote G6PD autophagic degradation and exacerbate oxidative stress damage to radiosensitize small cell lung cancer.
Phosphoproteomics reveals that cinobufotalin promotes intrahepatic cholangiocarcinoma cell apoptosis by activating the ATM/CHK2/p53 signaling pathway.
ITGB5 promotes innate radiation resistance in pancreatic adenocarcinoma by promoting DNA damage repair and the MEK/ERK signaling pathway.
eIF3a-PPP2R5A-mediated ATM/ATR dephosphorylation is essential for irinotecan-induced DNA damage response.
Zhong J, Liang L, Zhao N, Wang J, Shu P
Frontiers in pharmacology 2025;16:1562244
Frontiers in pharmacology 2025;16:1562244
Investigating the effects of miR-526b and miR-655 on doxorubicin sensitivity in breast cancer.
Opperman RM, Maiti S, Majumder M
Scientific reports 2025 Sep 29;15(1):33584
Scientific reports 2025 Sep 29;15(1):33584
Distinct Oxidative Stress Adaptations Driven by the Overexpression of miR-526b, miR-655, and COX-2 in Breast Cancer.
Opperman RM, Maiti S, Majumder M
International journal of molecular sciences 2025 Sep 18;26(18)
International journal of molecular sciences 2025 Sep 18;26(18)
A novel non-nad-based PARP1 inhibitor, Japoflavone B, triggered Caspase-3/GSDME-mediated pyroptosis through ROS/p38/p53 pathway in NSCLC.
Wan H, Wei J, Wang Y, Ge L, Hu Q, Li Y, Zhou B, Zeng X
Chemico-biological interactions 2025 Oct 22;420:111693
Chemico-biological interactions 2025 Oct 22;420:111693
Olaparib synergy screen reveals Exemestane induces replication stress in triple-negative breast cancer.
Yusoh NA, Su L, Chia SL, Tian X, Ahmad H, Gill MR
Molecular oncology 2025 Nov;19(11):3387-3408
Molecular oncology 2025 Nov;19(11):3387-3408
Synergistic antitumor effects and mechanistic insight of hypericin-mediated photodynamic therapy combined with Olaparib in MCF-7 BRCA1 wild-type breast cancer cells.
Hu J, Yu Y, Song J
Medical oncology (Northwood, London, England) 2025 Jul 9;42(8):317
Medical oncology (Northwood, London, England) 2025 Jul 9;42(8):317
Kaempferol Induces DNA Damage in Colorectal Cancer Cells by Regulating the MiR-195/miR-497-PFKFB4-Mediated Nonoxidative Pentose Phosphate Pathway.
Wu H, Du J, Hu P, Wang P, Wang Z, Ma J, Li Z
Journal of agricultural and food chemistry 2025 Apr 9;73(14):8312-8322
Journal of agricultural and food chemistry 2025 Apr 9;73(14):8312-8322
Nanoengineered Gallium Ion Incorporated Formulation for Safe and Efficient Reversal of PARP Inhibition and Platinum Resistance in Ovarian Cancer.
Li Y, Cen Y, Tu M, Xiang Z, Tang S, Lu W, Zhang H, Xu J
Research (Washington, D.C.) 2023;6:0070
Research (Washington, D.C.) 2023;6:0070
PI3K/mTOR inhibitors promote G6PD autophagic degradation and exacerbate oxidative stress damage to radiosensitize small cell lung cancer.
Deng H, Chen Y, Wang L, Zhang Y, Hang Q, Li P, Zhang P, Ji J, Song H, Chen M, Jin Y
Cell death & disease 2023 Oct 6;14(10):652
Cell death & disease 2023 Oct 6;14(10):652
Phosphoproteomics reveals that cinobufotalin promotes intrahepatic cholangiocarcinoma cell apoptosis by activating the ATM/CHK2/p53 signaling pathway.
Xia Z, Li M, Hu M, Lin Y, Atteh LL, Fu W, Gao L, Bai M, Huang C, Yue P, Liu Y, Meng W
Frontiers in oncology 2022;12:982961
Frontiers in oncology 2022;12:982961
ITGB5 promotes innate radiation resistance in pancreatic adenocarcinoma by promoting DNA damage repair and the MEK/ERK signaling pathway.
Wen X, Chen S, Chen X, Qiu H, Wang W, Zhang N, Liu W, Wang T, Ding X, Zhang L
Frontiers in oncology 2022;12:887068
Frontiers in oncology 2022;12:887068
eIF3a-PPP2R5A-mediated ATM/ATR dephosphorylation is essential for irinotecan-induced DNA damage response.
Mei C, Sun ZE, Tan LM, Gong JP, Li X, Liu ZQ
Cell proliferation 2022 Apr;55(4):e13208
Cell proliferation 2022 Apr;55(4):e13208
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