MA5-11940

antibody from Invitrogen Antibodies

Targeting: CHEK2 bA444G7, CDS1, CHK2, HuCds1, PP1425, RAD53

Western blot (Data presented on provider website)

Immunoprecipitation (Recommended by provider)

Antibody Data

Product number

MA5-11940

Provider

Invitrogen Antibodies

Product name

CHK2 Monoclonal Antibody (2CHK01 (DCS-293))

Antibody type

Monoclonal

Antigen

Recombinant full-length protein

Description

MA5-11940 targets Chk2 in immunofluorescence, immunoprecipiation, and Western blot applications and shows reactivity with Human samples. The antibody does not react with Chk1. The MA5-11940 immunogen is recombinant Chk2 protein.

Reactivity

Human

Host

Mouse

Isotype

IgG

Antibody clone number

2CHK01 (DCS-293)

Vial size

500 μL

Concentration

0.2 mg/mL

Storage

4°C

References

Submitted references

Ionizing radiation-dependent and independent phosphorylation of the 32-kDa subunit of replication protein A during mitosis.

Stephan H, Concannon C, Kremmer E, Carty MP, Nasheuer HP
Nucleic acids research 2009 Oct;37(18):6028-41

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Tumor suppressor protein C53 antagonizes checkpoint kinases to promote cyclin-dependent kinase 1 activation.

Jiang H, Wu J, He C, Yang W, Li H
Cell research 2009 Apr;19(4):458-68

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Polo-like kinase 1 and Chk2 interact and co-localize to centrosomes and the midbody.

Tsvetkov L, Xu X, Li J, Stern DF
The Journal of biological chemistry 2003 Mar 7;278(10):8468-75

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CHK2-decreased protein expression and infrequent genetic alterations mainly occur in aggressive types of non-Hodgkin lymphomas.

Tort F, Hernàndez S, Beà S, Martínez A, Esteller M, Herman JG, Puig X, Camacho E, Sánchez M, Nayach I, Lopez-Guillermo A, Fernández PL, Colomer D, Hernàndez L, Campo E
Blood 2002 Dec 15;100(13):4602-8