ABIN499619
antibody from antibodies-online
Targeting: CHEK2
bA444G7, CDS1, CHK2, HuCds1, PP1425, RAD53
Antibody data
- Antibody Data
- Antigen structure
- References [4]
- Comments [0]
- Validations
- Western blot [1]
- Immunocytochemistry [1]
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Validation data
Reference
Comment
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- Product number
- ABIN499619 - Provider product page
- Provider
- antibodies-online
- Product name
- anti-Checkpoint Kinase 2 (CHEK2) (N-Term) antibody
- Antibody type
- Polyclonal
- Antigen
- Human Chk2 (N-Terminus) Peptide (AP30226CP-N)
- Description
- Affinity chromatography purified via peptide column
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Epitope
- N-Term
- Isotype
- IgG
- Vial size
- 0.1 mg
- Concentration
- 1 mg/mL
- Storage
- Store the antibody undiluted at 2-8°C.
Submitted references p53AIP1, a potential mediator of p53-dependent apoptosis, and its regulation by Ser-46-phosphorylated p53.
Noxa, a BH3-only member of the Bcl-2 family and candidate mediator of p53-induced apoptosis.
A ribonucleotide reductase gene involved in a p53-dependent cell-cycle checkpoint for DNA damage.
Linkage of ATM to cell cycle regulation by the Chk2 protein kinase.
Oda K, Arakawa H, Tanaka T, Matsuda K, Tanikawa C, Mori T, Nishimori H, Tamai K, Tokino T, Nakamura Y, Taya Y
Cell 2000 Sep 15;102(6):849-62
Cell 2000 Sep 15;102(6):849-62
Noxa, a BH3-only member of the Bcl-2 family and candidate mediator of p53-induced apoptosis.
Oda E, Ohki R, Murasawa H, Nemoto J, Shibue T, Yamashita T, Tokino T, Taniguchi T, Tanaka N
Science (New York, N.Y.) 2000 May 12;288(5468):1053-8
Science (New York, N.Y.) 2000 May 12;288(5468):1053-8
A ribonucleotide reductase gene involved in a p53-dependent cell-cycle checkpoint for DNA damage.
Tanaka H, Arakawa H, Yamaguchi T, Shiraishi K, Fukuda S, Matsui K, Takei Y, Nakamura Y
Nature 2000 Mar 2;404(6773):42-9
Nature 2000 Mar 2;404(6773):42-9
Linkage of ATM to cell cycle regulation by the Chk2 protein kinase.
Matsuoka S, Huang M, Elledge SJ
Science (New York, N.Y.) 1998 Dec 4;282(5395):1893-7
Science (New York, N.Y.) 1998 Dec 4;282(5395):1893-7
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Supportive validation
- Submitted by
- antibodies-online (provider)
- Main image
- Experimental details
- Western blot analysis of Chk2 expression in K562 (A), Jurkat (B), and HL-60 (C) whole cell lysates with AP30226PU-N Chk2 antibody at 1 ?g /ml.
Supportive validation
- Submitted by
- antibodies-online (provider)
- Main image
- Experimental details
- Immunocytochemistry of Chk2 in Jurkat cells with AP30226PU-N Chk2 antibody at 1 ?g/ml.