ABIN965891
antibody from antibodies-online
Targeting: CHEK2
bA444G7, CDS1, CHK2, HuCds1, PP1425, RAD53
Antibody data
- Antibody Data
- Antigen structure
- References [5]
- Comments [0]
- Validations [0]
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- Product number
- ABIN965891 - Provider product page
- Provider
- antibodies-online
- Product name
- anti-Checkpoint Kinase 2 (CHEK2) antibody
- Antibody type
- Polyclonal
- Antigen
- The antiserum was produced against synthesized non-phosphopeptide derived from human Chk2 around the phosphorylation site of threonine 68.
- Description
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Vial size
- 100 μg
- Concentration
- 100ug/100ul.
- Storage
- -20°C
Submitted references ATM-dependent phosphorylation of ATF2 is required for the DNA damage response.
Conserved modes of recruitment of ATM, ATR and DNA-PKcs to sites of DNA damage.
Regulation of CHK2 by DNA-dependent protein kinase.
Hematopoietic cytokines enhance Chk1-dependent G2/M checkpoint activation by etoposide through the Akt/GSK3 pathway to inhibit apoptosis.
Activation of the DNA damage checkpoint and genomic instability in human precancerous lesions.
Bhoumik A, Takahashi S, Breitweiser W, Shiloh Y, Jones N, Ronai Z
Molecular cell 2005 May 27;18(5):577-87
Molecular cell 2005 May 27;18(5):577-87
Conserved modes of recruitment of ATM, ATR and DNA-PKcs to sites of DNA damage.
Falck J, Coates J, Jackson SP
Nature 2005 Mar 31;434(7033):605-11
Nature 2005 Mar 31;434(7033):605-11
Regulation of CHK2 by DNA-dependent protein kinase.
Li J, Stern DF
The Journal of biological chemistry 2005 Mar 25;280(12):12041-50
The Journal of biological chemistry 2005 Mar 25;280(12):12041-50
Hematopoietic cytokines enhance Chk1-dependent G2/M checkpoint activation by etoposide through the Akt/GSK3 pathway to inhibit apoptosis.
Jin ZH, Kurosu T, Yamaguchi M, Arai A, Miura O
Oncogene 2005 Mar 17;24(12):1973-81
Oncogene 2005 Mar 17;24(12):1973-81
Activation of the DNA damage checkpoint and genomic instability in human precancerous lesions.
Gorgoulis VG, Vassiliou LV, Karakaidos P, Zacharatos P, Kotsinas A, Liloglou T, Venere M, Ditullio RA Jr, Kastrinakis NG, Levy B, Kletsas D, Yoneta A, Herlyn M, Kittas C, Halazonetis TD
Nature 2005 Apr 14;434(7035):907-13
Nature 2005 Apr 14;434(7035):907-13
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