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LearnABIN871442
antibody from antibodies-online
Targeting: CHEK2
bA444G7, CDS1, CHK2, HuCds1, PP1425, RAD53
Western blotAntibody data
- Antibody Data
- Antigen structure
- References [3]
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- Product number
- ABIN871442 - Provider product page
- Provider
- antibodies-online
- Product name
- anti-Checkpoint Kinase 2 (CHEK2) (AA 514-518) antibody
- Antibody type
- Polyclonal
- Description
- Affinity purified
- Reactivity
- Human
- Host
- Rabbit
- Epitope
- AA 514-518
- Vial size
- 50 μL
- Storage
- Store at -20°C for long term preservation (recommended). Store at 4°C for short term use.
Submitted references The hCds1 (Chk2)-FHA domain is essential for a chain of phosphorylation events on hCds1 that is induced by ionizing radiation.
Threonine 68 is required for radiation-induced phosphorylation and activation of Cds1.
Threonine 68 phosphorylation by ataxia telangiectasia mutated is required for efficient activation of Chk2 in response to ionizing radiation.
Lee CH, Chung JH
The Journal of biological chemistry 2001 Aug 10;276(32):30537-41
The Journal of biological chemistry 2001 Aug 10;276(32):30537-41
Threonine 68 is required for radiation-induced phosphorylation and activation of Cds1.
Melchionna R, Chen XB, Blasina A, McGowan CH
Nature cell biology 2000 Oct;2(10):762-5
Nature cell biology 2000 Oct;2(10):762-5
Threonine 68 phosphorylation by ataxia telangiectasia mutated is required for efficient activation of Chk2 in response to ionizing radiation.
Ahn JY, Schwarz JK, Piwnica-Worms H, Canman CE
Cancer research 2000 Nov 1;60(21):5934-6
Cancer research 2000 Nov 1;60(21):5934-6
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