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- Product number
- 10995-1-AP - Provider product page
- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#10995-1-AP, RRID:AB_2264230
- Product name
- HSP70 antibody
- Antibody type
- Polyclonal
- Description
- HSP70 antibody (Cat. #10995-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse, rat and has been validated for the following applications: FC, IF, IHC, IP, WB, ELISA.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references Electroacupuncture Alleviates Oxidative Stress and Cuproptosis in Metabolic Dysfunction-Associated Steatotic Liver Disease Mice Through Activation of the NRF2/ARE Pathway.
Characteristics of Exosomes and Microbiota in the Decidua of Patients With Early Pregnancy Loss and Their Impact on Trophoblast Cells.
Seminal plasma extracellular vesicle-derived miR-296-3p targets PLA2G6 to enhance boar sperm motility by lowering Lys Phosphatidylcholine.
Sparc-driven p62-dependent mitochondrial oxidative stress exacerbates myocardial ischemia and is attenuated by ginsenoside CK.
Combination of Hypoxia-Preconditioned ADSCs and Deferoxamine Can Speed Up the Healing of Diabetic Wounds by Promoting Angiogenesis and Regulating Macrophage Polarization.
TEAD1 Enhances Exosome Secretion and Promotes Exosome-Mediated Tissue Regeneration.
Label-free streamlined photoacoustic image guidance facilitates NIR-II photoablation in models of melanoma lung metastases.
O-GlcNAcase promotes dendritic spine morphogenesis while downregulating their GluA2-containing AMPA receptors.
Decreased Glucose Metabolism and Declined Chaperones Are Unique Features Required for the Survival of Senescent Fibroblasts and Pyruvate Dehydrogenase Is a Potent Senolytic Target.
Novel Ce/Cu-modified black ceramics disrupted mitochondrial dysfunction and tricarboxylic acid cycle to induce cuproptosis in osteosarcoma cells.
Extracellular vesicles-derived hybrid biomimetic nanoplatforms camouflaged Golgi apparatus-targeted aggregation induced emission photosensitizer to elicit pyroptosis and immunogenic cell death for efficient antitumor photoimmunotherapy.
Copper-induced duodenal injury: Unveiling the dual role of cuproptosis and ferroptosis via the FDX1/GPX4 axis.
Mn(3)O(4)-potentiated bifunctional hydrogel for mild temperature-controlled tumor ablation and osteogenesis.
Identification of specific molecular markers in severe heatstroke using transcriptomics techniques.
Autocatalytic Signal Amplification via Orthogonal Recognition of Dual Proteins on the Surface of Serum Extracellular Vesicles for Precise Diagnosis of Prostate Cancer.
Neuroprotective Effects of Desert Milk Exosomes in LPS-Induced Cognitive Decline: Role of Microglial M2 Polarization and AMPK Signaling.
Amyloidogenic oligomers derived from TDP-43 LCD promote the condensation and phosphorylation of TDP-43.
The Whole Transcriptome Sequencing Profile of Serum-Derived Exosomes and Potential Pathophysiology of Age-Related Hearing Loss.
Combination of YAP inhibition and photodynamic therapy induces dual DNA damage and activates STING pathway to enhance immunotherapy in uveal melanoma.
O-GlcNAc transferase couples nutrient availability to synaptic plasticity in paraventricular neurons to regulate satiety.
Inhibition of dengue virus type 2 by hypericin mediated through viral envelope protein interaction.
PDHA1-acetylation signaling suppresses cuproptosis to attenuate anti-androgen effect in prostate cancer.
Aryl hydrocarbon receptor-mediated transcriptional regulation of HSP70 exacerbates endoplasmic reticulum stress in lupus nephritis.
Bmscs loaded exosome hydrogel promotes the repair of rotator cuff injury in rats in vivo.
Neonatal inflammation induces ventral hippocampal microglial priming via epigenetic regulation of BAG3 to enhance adult depression susceptibility in mice.
An autonomous siRNA delivery system targeting NLRP3: implications in Parkinson's disease.
Near infrared enhanced palladium loaded siraitia grosvenorii carbon dots amplify mitophagy for acute lung injury immunotherapy.
Dual-responsive PDA-HP hydrogel enables mitochondria-targeted mild photothermal therapy for spinal cord repair.
Light sensing enhances thermotolerance and competitive fitness via serotonergic signaling in an eyeless organism.
Multifunctional exosome-driven tumor immunotherapy sensitization: converting intratumoral bacteria into antitumor fighters.
Ascites circRNA ASCOR Drives Platinum Resistance of High-Grade Serous Ovarian Cancer by Facilitating RPA1 Nuclear Translocation.
Fungal Exosome-Like Nanoparticles from Huaier (Trametes robiniophila Murr.) Exhibit Antibreast Cancer Activity.
Hsp70-Targeting Chimeras Enable Dual Proteasomal and Lysosomal Degradation of Intracellular and Extracellular Proteins.
MiR-423-5p inhibition alleviates podocyte apoptosis in membranous nephropathy by targeting WT1/β-catenin axis.
Identification and Screening of Lactate-Related Genes as Molecular Markers for Early Diagnosis of Steroid-Induced Osteonecrosis of the Femoral Head.
Remote mobilization of gut Tregs exosomes serves as nanoshuttles for targeted cardioprotection against ischemia/reperfusion injury by ginseng polysaccharides.
Hijacking client instability to selectively disrupt HSP90-driven glucocorticoid receptor activation.
STI1 domains coordinate partitioning of UBQLN2 into stress-induced condensates.
Probiotic Bifidobacterium Confers Protection Against Heat Stroke Through Enhancement of Intestinal Barrier Function in Rats.
Pathogenic mechanisms of amyotrophic lateral sclerosis-linked VAPB P56S mutation in the degeneration of corticospinal motor neurons.
Ultrasound-Targeted Nanobubbles Codelivering NKP-1339 and miR-142-5p for Synergistic Mitochondrial Immunogenic Cell Death and PD-L1 Inhibition in Cancer Therapy.
A Liquid Band-Aid with Mesenchymal Stem Cell-derived Exosomes for Wound Healing in Mice.
Hyperthermia Inhibits Growth and Stemness of Esophageal Squamous Cell Carcinoma Cells Through Promoting Degradation of GLI1.
Exosome-Delivered circFOXP1 Upregulates Autophagy and Promotes Hepatocellular Carcinoma Progression Through Its Encoded p196 Protein Targeting the KHDRBS3/ULK1 Axis.
S-Adenosylmethionine Inhibits Plasminogen-Activating Inhibitor-1 and Protects Male Mice From FOLFOX-Induced Liver Injury.
Silk fibroin-collagen hydrogel loaded with IGF1-CESCs attenuates intervertebral disk degeneration by accelerating annulus fibrosus healing in rats.
Hybrid NIR-responsive liposome/hydrogel platform mediating chemo-photothermal therapy of retinoblastoma enhanced by quercetin as an adjuvant.
High salt-induced osmotic stress differentially modulates hepatocellular and renal carcinoma cell proliferation.
Exosomes derived from miR-26a-5p-modified adipose mesenchymal stem cells improve wound healing by targeting MAP2K4.
Injectable exosome-reinforced konjac glucomannan composite hydrogel for repairing cartilage defect: activation of endogenous antioxidant pathways.
Unveiling the role of hexon-associated host proteins in fowl adenovirus serotype 4 replication.
Brown adipocyte-derived exosomes in type 2 diabetes mellitus impair endothelial function via regulating intracellular calcium cycle.
LncRNA PVT1 promotes cuproptosis through transcriptional activation of FDX1 in colorectal cancer.
Glyphosate targets FYN to regulate glycolysis and promote glioblastoma proliferation: A network toxicology study.
Bisphenol A promotes OSCC progression via GABBR1-mediated MAPK signaling and macrophage polarization: A network toxicology based study.
Oncolytic microgels with regulated antibody release augment tumor immunotherapy.
Iron overload exaggerates renal ischemia-reperfusion injury by promoting tubular cuproptosis via interrupting function of LIAS.
Plasma Exosomal circRNAs as Potential Biomarkers for Patients with Septic Shock-Induced Acute Kidney Injury.
Icariside II attenuates renal fibrosis through mTOR signaling modulation: an integrated approach combining network pharmacology, molecular dynamics, and in vitro validation.
Novel E-F ring derivatives of aconitine scaffold as potent Hsp90 inhibitors for the treatment of colorectal cancer.
PDLIM4 drives gastric cancer malignant progression and cisplatin resistance by inhibiting HSP70 ubiquitination and degradation via competitive interaction with STUB1.
Proteasomes suppress anticancer drug-induced cytotoxicity by inhibiting mitochondrial protein import and promoting ROS-BNIP3-mediated mitophagy.
Heat shock protein HSPA1A promotes porcine epidemic diarrhea virus replication by targeting the viral RNA-dependent RNA polymerase.
Multi-modal microcarriers reprogram mitochondrial metabolism and activate efferocytosis in macrophages for osteoporotic bone repair.
Ferrum@albumin assembled nanoclusters inhibit NF-κB signaling pathway for NIR enhanced acute lung injury immunotherapy.
TRIM10β upregulation promotes microtubule destabilization and triggers proteotoxic stress.
Dysregulated oxidative stress and lactate levels in treatment-resistant schizophrenia.
H(2)S-Activated Theranostic Platform for Precise Photoablation of Colorectal Tumors with NIR-II Dual-Modal Phototherapy.
Antihypertension and Improvement Effects of Hexapeptide APPLRP on Exosomes-Mediated Vascular Endothelial Inflammation in Spontaneously Hypertensive Rats.
Overexpression of Hspa1b in the mouse hippocampus may be associated with major depressive disorder.
Multi-cellular phenotypic dynamics during the progression of an immunocompetent breast cancer model.
Brigatinib activates inflammasomes: Implication for immune-related adverse events.
A kinase-independent Bcr-Abl function mediating an Hsp70-Bim protein-protein interaction in chronic myeloid leukemia.
Exosomes enriched with miR-31-3p from keratinocytes under oxidative stress promote vitiligo progression by destructing melanocytes and activating CD8(+) T cells.
The depletion of TFAM and p-β-catenin(S552) in mitochondria in response to BoAHV-1 productive infection leads to decreased mitochondrial biogenesis.
Disruption of BAG3-mediated BACE1 stabilization alleviates neuropathology and memory deficits in a mouse model of Alzheimer's disease.
Asb10 accelerates pathological cardiac remodeling by stabilizing HSP70.
A label-free fluorescence aptasensor for salivary exosomes based on a nano-micro dual-scale signal amplification strategy.
Breast cancer stem cell-derived exosomal lnc-PDGFD induces fibroblast-niche formation and promotes lung metastasis.
Longitudinal single-cell RNA sequencing reveals a heterogeneous response of plasma cells to colonic inflammation.
Tumor-Resident Intracellular Bacteria Scavenger Activated In Situ Vaccines for Potent Cancer Photoimmunotherapy.
Identification of Potential Amblyomma americanum Antigens After Vaccination with Tick Extracellular Vesicles in White-Tailed Deer.
Placental mesenchymal stem cell-derived exosomes treat endometrial injury in a rat model of intrauterine adhesions.
Phenethyl isothiocyanate ameliorates liver injuries secondary to inflammatory bowel disease.
E-jet 3D printed aligned nerve guidance conduits incorporated with decellularized extracellular matrix hydrogel encapsulating extracellular vesicles for peripheral nerve repair.
Role of DLAT in cuproptosis and autophagy in hippocampal tissue of PTSD rats with high-voltage electrical burns.
Optically controllable nanoregulators enable tumor-specific pro-ferroptosis lipometabolic reprogramming for in-situ adjuvant-free vaccination.
Charge-reversed small extracellular vesicles from human adipose-derived mesenchymal stromal cells attenuate renal fibrosis postacute kidney injury by inhibiting epithelial-mesenchymal transition progression in SD rat model.
Hsp70 incompletely disaggregates misfolded K488X-menin to promote tumourigenesis in a family with multiple endocrine neoplasia type 1.
Diallyl Trisulfide From Garlic Regulates RAB18 Phase Separation to Inhibit Lipophagy and Induce Cuproptosis in Hepatic Stellate Cells for Antifibrotic Effects.
Novel insights into human CRISP2: localization in reproductive tissues and sperm, and molecular characterization†.
miR166u -enriched Polygonatum sibiricum exosome-like nanoparticles alleviate colitis by improving intestinal barrier through the TLR4/AKT pathway.
Oxaliplatin accelerates immunogenic cell death by activating the cGAS/STING/TBK1/IRF5 pathway in gastric cancer.
Kasumi-1 exosome plays a major T-cell immune evasion role in TP53-type acute leukemia.
Small and Large Extracellular Vesicles From Human Preovulatory Follicular Fluid Display Distinct ncRNA Cargo Profiles and Differential Effects on KGN Granulosa Cells.
Exosome-Functionalized Hydrogels Improve Cartilage Repair by Modulating BMSCs Migration and Differentiation.
Endothelial cell-secreted bone targeting exosomes promote angiogenesis coupling with osteogenesis via the PERK-ATF4-CRELD2 pathway.
Ribosome association inhibits stress-induced gene mRNA localization to stress granules.
Mechanisms underlying the estradiol mediated protection of yak oviduct epithelial cells against ER-Ca(2+) imbalance.
Adipose tissue macrophages-derived exosomal MiR-500a-5p under high glucose promotes adipocytes inflammation by suppressing Nrf2 expression.
C9ORF72 poly-PR induces TDP-43 nuclear condensation via NEAT1 and is modulated by HSP70 activity.
Mechanism of hsa_circ_0069443 promoting early pregnancy loss through ALKBH5/FN1 axis in trophoblast cells.
The Expression Pattern and Functional Analysis of Extracellular Vesicle Long Non-Coding RNAs from Uterine Fluid During Implantation in Pig.
Enhancing inhibitory effect in SMMC-7721 hepatoma cells through combined treatment of gallic acid and hUC-MSCs-Exos.
The new anti-angiogenesis perspective of rheumatoid arthritis with geniposide: Reducing the extracellular release of HSP70 in HUVECs.
miRNA-21-5p is an important contributor to the promotion of injured peripheral nerve regeneration using hypoxia-pretreated bone marrow-derived neural crest cells.
AAV mediated carboxyl terminus of Hsp70 interacting protein overexpression mitigates the cognitive and pathological phenotypes of APP/PS1 mice.
Angiogenesis-promoting effect of SKP-SC-EVs-derived miRNA-30a-5p in peripheral nerve regeneration by targeting LIF and ANGPT2.
Pyruvate Kinase M2-Responsive Release of Paclitaxel and Indoleamine 2,3-Dioxygenase Inhibitor for Immuno-Chemotherapy of Nonsmall Cell Lung Cancer.
hBMSC-EVs alleviate weightlessness-induced skeletal muscle atrophy by suppressing oxidative stress and inflammation.
Chaihu Shugan San Exerts Antidepressant Effects by Regulating Glucocorticoid Metabolism in CUMS Rats and Network Pharmacology Provides Complementary Mechanistic Insights.
Uterine-derived exosomes induce the M2 polarization of macrophages via miR-210-3p/ATP5D to promote endometriosis progression.
Methionine Modulates the Growth and Development of Heat-Stressed Dermal Papilla Cells via the Wnt/β-Catenin Signaling Pathway.
Low shear stress induces vascular endothelial cells apoptosis via miR-330 /SOD2 /HSP70 signaling pathway.
3D-cultured DFAT spheroid-derived exosomes promote aged wound healing via modulation of the NF-κB/Serpine1 pathway.
Sp3 ameliorated experimental autoimmune encephalomyelitis by triggering Socs3 in Th17 cells.
Immunomodulatory copper-based polyphenol nanozyme for diabetic infectious wound healing via NIR amplified cuproptosis bacteriostat in synergy with ferroptosis inhibition anti-inflammation.
Jahn-Teller distortion-engineered self-propelled nanorobots for mitochondrial targeting and bioenergetic disruption in tumor therapy.
Stage-specific TRIM10 expression regulates erythroid maturation.
Overcoming ELDR-mediated cancer cell survival in vitro and in vivo via sphingomyelin-driven TRPML1 inactivation and TFEB suppression through lysosomal HSP70 targeting.
ERβ/circAHNAK Axis Inhibits USP10-FMR1 Deubiquitination to Prevent m⁶A-Mediated ADAM17 Decay and Promote Angiogenesis in Clear Cell Renal Cell Carcinoma.
TIA1-mediated stress granules promote neurodegeneration by sequestering HSP70 mRNA in C9orf72 mice.
A novel single-cell level evaluation method for corneal endothelial cell function.
Upregulation of E3 ligase UBR2 in acetaldehyde-treated C2C12 myotubes and its potential involvement in fast-twitch muscle atrophy in alcohol-fed rats.
Immunogenic cuproptosis in cancer immunotherapy via an in situ cuproptosis-inducing system.
Multifunctional targeted nanosystem based on aggregation-induced emission: Enhanced synergistic mild-photothermal chemotherapy of prostate cancer via downregulation of heat shock protein 70 under NIR-II imaging.
The BAG3-HSP70-CHIP axis controls the degradation of TGFBR2 in cardiac fibroblasts.
Vascular Smooth Muscle-Secreted Exosomal X26nt Impedes Atherosclerosis Progression via the c-FOS/XBP1/SOD1 Axis.
Episodic transport of protein aggregates achieves a positive size selectivity in aggresome formation.
MRO/HNRNPU/CCL5 feedback loop amplifies M2 macrophage and breast cancer cell crosstalk to drive progression.
A hollow-tube-like hydrospongel for multimodal therapy of advanced colorectal cancer.
Bone marrow mesenchymal stem cell derived exosomal miR-361-5p reversed the effect of bortezomib on multiple myeloma.
Self-propelling intelligent nanomotor: A dual-action photothermal and starvation strategy for targeted deep tumor destruction.
Reprogramming Lung Redox Homeostasis by NIR Driven Ultra-Small Pd Loaded Covalent Organic Framework Inhibits NF-κB Pathway for Acute Lung Injury Immunotherapy.
Targeted Regulation of HSP70 by the ARP2/3 Complex in Mammary Epithelial Cells and Its Impact on Host Cell Apoptosis.
Chlorophyllin exerts synergistic anti-tumor effect with gemcitabine in pancreatic cancer by inducing cuproptosis.
Estradiol Alleviates Elevated Temperature-Induced Damage in Yak Oviductal Epithelial Cells by Maintaining Endoplasmic Reticulum Calcium Homeostasis.
Development of Novel PRMT7 Inhibitors for the Treatment of Prostate Cancer.
Neural-induced human adipose tissue-derived stem cell secretome exerts neuroprotection against rotenone-induced Parkinson's disease in rats.
In vitro study on the promotion of osteogenic differentiation by mitochondrial-derived vesicles through activation of inflammation and reprogramming of metabolic pathways.
Canolol Alleviates Ethanol-Induced Gastric Ulcer by Inhibiting p38 MAPK/NF-κB/NLRP3 Pathway.
An unconventional autophagic pathway that inhibits ATP secretion during apoptotic cell death.
UCH-L1 Inhibitor Alleviates Nerve Damage Caused by Moyamoya Disease.
Immunomodulatory effect of PLGA-encapsulated mesenchymal stem cells-derived exosomes for the treatment of allergic rhinitis.
Heat acclimation with probiotics-based ORS supplementation alleviates heat stroke-induced multiple organ dysfunction via improving intestinal thermotolerance and modulating gut microbiota in rats.
Single cell analyses reveal the PD-1 blockade response-related immune features in hepatocellular carcinoma.
mRNA expression profiles in muscle-derived extracellular vesicles of Large White and wild boar piglets reveal their potential roles in immunity and muscle phenotype.
Polystyrene nanoparticles trigger aberrant condensation of TDP-43 and amyotrophic lateral sclerosis-like symptoms.
Discovery of novel quinoline scaffold selective estrogen receptor degraders (SERDs) for treatment of ER positive breast cancer with enhanced antiproliferative bioactivity through immunogenic cell death (ICD) effects.
Umbilical cord blood-derived exosomes attenuate dopaminergic neuron damage of Parkinson's disease mouse model.
Hypoxic microenvironment promotes diabetic wound healing by polarizing macrophages to the M2 phenotype in vivo.
Biomimetic nanocomplex based corneal neovascularization theranostics.
Novel Insights Into DLAT's Role in Alzheimer's Disease-Related Copper Toxicity Through Microglial Exosome Dynamics.
High temperature ameliorates high-fat diet-induced obesity by promoting ceramide breakdown in skeletal muscle tissue.
CaMKII suppresses proteotoxicity by phosphorylating BAG3 in response to proteasomal dysfunction.
Short Repeat Ribonucleic Acid Reduces Cytotoxicity by Preventing the Aggregation of TDP-43 and Its 25 KDa Carboxy-Terminal Fragment.
S-RBD-modified and miR-486-5p-engineered exosomes derived from mesenchymal stem cells suppress ferroptosis and alleviate radiation-induced lung injury and long-term pulmonary fibrosis.
m6A-modified exosome-derived circHIF1α binding to KH domain of IGF2BP3 mediates DNA damage and arrests G1/S transition phase to resists bacterial infection in bacteremia.
Tumor Microenvironment-Responsive Biodegradable Nanomedicine for Self-Enhanced Synergistic Chemo-, Photothermal, and Chemodynamic Therapy.
Comparative investigation of exosome extraction from rat bone marrow mesenchymal stem cells using three different methodologies.
Caspase-2 is a condensate-mediated deubiquitinase in protein quality control.
Mucosal Exosome Proteomics of Hybrid Grouper Epinephelus fuscoguttatus♀ × E. lanceolatus♂ Infected by Pseudomonas plecoglossicida.
Exosome-derived circ-001422 promotes tumor-associated macrophage M2 polarization to accelerate the progression of glioma.
Analysis of the effects of M2 macrophage-derived PDE4C on the prognosis, metastasis and immunotherapy benefit of osteosarcoma.
Reduction of Filamin C Results in Altered Proteostasis, Cardiomyopathy, and Arrhythmias.
An ATP13A1-assisted topogenesis pathway for folding multi-spanning membrane proteins.
A combination of PD-L1-targeted IL-15 mRNA nanotherapy and ultrasound-targeted microbubble destruction for tumor immunotherapy.
Selenomethionine alleviates chronic heat stress-induced breast muscle injury and poor meat quality in broilers via relieving mitochondrial dysfunction and endoplasmic reticulum stress.
Bi(2)S(3)/Ti(3)C(2)-TPP nano-heterostructures induced by near-infrared for photodynamic therapy combined with photothermal therapy on hypoxic tumors.
L-Theanine alleviates heat stress through modulation of gut microbiota and immunity.
Plasma extracellular vesicle synaptic proteins as biomarkers of clinical progression in patients with Parkinson's disease.
The mitochondrial UPR induced by ATF5 attenuates intervertebral disc degeneration via cooperating with mitophagy.
Ponicidin-induced conformational changes of HSP90 regulates the MAPK pathway to relieve ulcerative colitis.
Reactive metabolite of trovafloxacin activates inflammasomes: Implications for trovafloxacin-induced liver injury.
Exosomes from adipose-derived stem cells regulate macrophage polarization and accelerate diabetic wound healing via the circ-Rps5/miR-124-3p axis.
NIR triggered polydopamine coated cerium dioxide nanozyme for ameliorating acute lung injury via enhanced ROS scavenging.
Deciphering ER stress-unfolded protein response relationship by visualizing unfolded proteins in the ER.
CGG repeats in the human FMR1 gene regulate mRNA localization and cellular stress in developing neurons.
Ultrashort wave diathermy inhibits pulmonary inflammation in mice with acute lung injury in a HSP70 independent way: a pilot study.
Engineered Luminescent Oncolytic Vaccinia Virus Activation of Photodynamic-Immune Combination Therapy for Colorectal Cancer.
Effects of spinal cord injury associated exosomes delivered tRF-41 on the progression of spinal cord injury progression.
Nano-Se exhibits limited protective effect against heat stress induced poor breast muscle meat quality of broilers compared with other selenium sources.
Enhanced therapeutic impact of Shikonin-encapsulated exosomes in the inhibition of colorectal cancer progression.
Exploring and validating heating dynamics in a radio-frequency electromagnetic field-based resonant chamber for mouse hyperthermia research.
Extracellular vesicles separated from goat milk by differential centrifugation coupled with sodium citrate pretreatments.
Protective effects of L-theanine and dihydromyricetin on reproductive function in male mice under heat stress.
FOXA2 activates HIF2α expression to promote tumor progression and is regulated by the E3 ubiquitin ligase VHL in renal cell carcinoma.
Ambra1 in exosomes secreted by HK-2 cells damaged by supersaturated oxalate induce mitophagy and autophagy-ferroptosis in normal HK-2 cells to participate in the occurrence of kidney stones.
Huc-MSC-derived exosomal miR-144 alleviates inflammation in LPS-induced preeclampsia-like pregnant rats via the FosB/Flt-1 pathway.
Deep learning enables the discovery of a novel cuproptosis-inducing molecule for the inhibition of hepatocellular carcinoma.
Differential Proteomic Profiles of Coronary Serum Exosomes in Acute Myocardial Infarction Patients with or Without Diabetes Mellitus: ANGPTL6 Accelerates Regeneration of Endothelial Cells Treated with Rapamycin via MAPK Pathways.
Disrupted HSF1 regulation in normal and exceptional brain aging.
The augmentation of cytotoxic immune cell functionality through physical exertion bolsters the potency of chemotherapy in models of mammary carcinoma.
CircMTA2 Drives Gastric Cancer Progression through Suppressing MTA2 Degradation via Interacting with UCHL3.
Recruitment of BAG2 to DNAJ-PKAc scaffolds promotes cell survival and resistance to drug-induced apoptosis in fibrolamellar carcinoma.
Protein phosphatase 1 regulatory subunit 15 A promotes translation initiation and induces G2M phase arrest during cuproptosis in cancers.
Herpes simplex virus type 1 modifies the protein composition of extracellular vesicles to promote neurite outgrowth and neuroinfection.
Sirtuin 7 ameliorates cuproptosis, myocardial remodeling and heart dysfunction in hypertension through the modulation of YAP/ATP7A signaling.
Skin as outermost immune organ of vertebrates that elicits robust early immune responses after immunization with glycoprotein of spring viraemia of carp virus.
Immunomodulatory effect of mesenchymal stem cells-derived extracellular vesicles to modulate the regulatory T cells and Th1/Th2 imbalance in peripheral blood mononuclear cells of patients with allergic rhinitis.
Exosome-delivered NR2F1-AS1 and NR2F1 drive phenotypic transition from dormancy to proliferation in treatment-resistant prostate cancer via stabilizing hormonal receptors.
Butyrolactone-I from Marine Fungal Metabolites Mitigates Heat-Stress-Induced Apoptosis in IPEC-J2 Cells and Mice Through the ROS/PERK/CHOP Signaling Pathway.
Bongkrekic acid alleviates airway inflammation via breaking the mPTP/mtDAMPs/RAGE feedback loop in a steroid-insensitive asthma model.
N-acetylcysteine stimulates the proliferation and differentiation in heat-stressed skeletal muscle cells.
Exosomal miR-106a-5p derived from intermittently hypoxic non-small-cell lung cancer increases tumor malignancy.
Eupalinolide B suppresses pancreatic cancer by ROS generation and potential cuproptosis.
Data on mitochondrial respiratory function in skeletal muscle of adult male mice in response to 3-weeks heat stress.
Dietary purple potato supplement attenuates DSS-induced colitis in mice: impact on mitochondrial function.
Dual RNA sequencing of Helicobacter pylori and host cell transcriptomes reveals ontologically distinct host-pathogen interaction.
Quantitative Measurement of Transthyretin Mistargeting by Proximity Labeling and Parallel Reaction Monitoring.
DNAJC8: a prognostic marker and potential therapeutic target for hepatocellular carcinoma.
Cuproptosis enhances docetaxel chemosensitivity by inhibiting autophagy via the DLAT/mTOR pathway in prostate cancer.
Exploiting immunostimulatory mechanisms of immunogenic cell death to develop membrane-encapsulated nanoparticles as a potent tumor vaccine.
Fluorescence Tracking of Small Extracellular Vesicles In Vivo.
Quantitative proteomic analysis of local and systemic extracellular vesicles during Eimeria falciformis infectious cycle in the host.
USP14 Positively Modulates Head and Neck Squamous Carcinoma Tumorigenesis and Potentiates Heat Shock Pathway through HSF1 Stabilization.
Evaluation the role of cuproptosis-related genes in the pathogenesis, diagnosis and molecular subtypes identification of atherosclerosis.
Changes in the components of salivary exosomes due to initial periodontal therapy.
Targeting TNFAIP2 induces immunogenic cell death and sensitizes glioblastoma multiforme to anti-PD-1 therapy.
Phenyl dialkynylcarbinols, a Bioinspired Series of Synthetic Antitumor Acetylenic Lipids.
Tumor-repopulating cell-derived microparticles elicit cascade amplification of chemotherapy-induced antitumor immunity to boost anti-PD-1 therapy.
Effective myocardial infarction treatment by targeted accumulation of Sulforaphane using porous magnetic silica nanoparticles.
M2 macrophage exosomal LINC01001 promotes non-small cell lung cancer development by affecting METTL3 and glycolysis pathway.
Nuclear import carrier Hikeshi cooperates with HSP70 to promote murine oligodendrocyte differentiation and CNS myelination.
The proteomics analysis of extracellular vesicles revealed the possible function of heat shock protein 60 in Helicobacter pylori infection.
The HDAC inhibitor HFY-4A improves TUSC2 transcription to induce immunogenic cell death in breast cancer.
Pre-Induced ICD Membrane-Coated Carrier-Free Nanoparticles for the Personalized Lung Cancer Immunotherapy.
SIRT2 regulates extracellular vesicle-mediated liver-bone communication.
miR-27a-3p relieves heat stress-induced mitochondrial damage and aberrant milk protein synthesis through MEK/ERK pathway in BMECs.
Bone mesenchymal stem cell-derived exosomes involved co-delivery and synergism effect with icariin via mussel-inspired multifunctional hydrogel for cartilage protection.
Viral subversion of selective autophagy is critical for biogenesis of virus replication organelles.
Exosomes from tubular epithelial cells undergoing epithelial-to-mesenchymal transition promote renal fibrosis by M1 macrophage activation.
HSPA1A ameliorated spinal cord injury in rats by inhibiting apoptosis to exert neuroprotective effects.
Taxol‑resistant breast cancer cell‑derived exosome‑delivered miR‑187‑5p regulates the growth of breast cancer cells via ABCD2 and Wnt/β‑catenin signaling.
PTEN Deficiency Facilitates Exosome Secretion and Metastasis in Cholangiocarcinoma by Impairing TFEB-mediated Lysosome Biogenesis.
A curcumin analogue GO-Y030 depletes cancer stem cells by inhibiting the interaction between the HSP70/HSP40 complex and its substrates.
Cytokine profiles of plasma extracellular vesicles as progression biomarkers in Parkinson's disease.
Extracellular vesicles from Zika virus-infected cells display viral E protein that binds ZIKV-neutralizing antibodies to prevent infection enhancement.
Near-Infrared Phototheranostic Iron Pyrite Nanocrystals Simultaneously Induce Dual Cell Death Pathways via Enhanced Fenton Reactions in Triple-Negative Breast Cancer.
A cytosolic surveillance mechanism activates the mitochondrial UPR.
Engineered allostery in light-regulated LOV-Turbo enables precise spatiotemporal control of proximity labeling in living cells.
Recruitment of BAG2 to DNAJ-PKAc scaffolds promotes cell survival and resistance to drug-induced apoptosis in fibrolamellar carcinoma.
Albumosomes formed by cytoplasmic pre-folding albumin maintain mitochondrial homeostasis and inhibit nonalcoholic fatty liver disease.
Dextran 40 hybrid biomimetic bismuth-nanoflower designed for NIR II-triggered hypoxic tumor thermoradiotherapy via macrophage escape.
Carnosinase-1 Knock-Out Reduces Kidney Fibrosis in Type-1 Diabetic Mice on High Fat Diet.
Long noncoding RNA HITT coordinates with RGS2 to inhibit PD-L1 translation in T cell immunity.
Control of SOX2 protein stability and tumorigenic activity by E3 ligase CHIP in esophageal cancer cells.
Combination therapy with BMSCs‑exosomes and porous tantalum for the repair of femur supracondylar defects.
Roles of hypoxic environment and M2 macrophage-derived extracellular vesicles on the progression of non-small cell lung cancer.
Cellular Exposure to Chloroacetanilide Herbicides Induces Distinct Protein Destabilization Profiles.
Quantitative Measurement of Secretory Protein Mistargeting by Proximity Labeling and Parallel Reaction Monitoring.
Lysine butyrylation of HSP90 regulated by KAT8 and HDAC11 confers chemoresistance.
Cardiac myofibrillogenesis is spatiotemporally modulated by the molecular chaperone UNC45B.
Extracellular vesicles from mesenchymal stem cells reduce neuroinflammation in hippocampus and restore cognitive function in hyperammonemic rats.
Exosomal microRNAs regulate the heat stress response in sea cucumber Apostichopus japonicus.
iASPP suppression mediates terminal UPR and improves BRAF-inhibitor sensitivity of colon cancers.
Hypoxia aggravates the burden of yellowstripe goby (Mugilogobius chulae) under atorvastatin exposure.
lncRNA SND1-IT1 delivered via intracerebral hemorrhage-derived exosomes affect the growth of human microglia by regulating the miR-124-3p/MTF1 axis.
Exosomes Derived from AT2R-Overexpressing BMSC Prevent Restenosis After Carotid Artery Injury by Attenuating the Injury-Induced Neointimal Hyperplasia.
Distinctive chaperonopathy in skeletal muscle associated with the dominant variant in DNAJB4.
Sex-Inclined Piwi-Interacting RNAs in Serum Exosomes for Sex Determination in the Greater Amberjack (Seriola dumerili).
Negatively charged bladder acellular matrix loaded with positively charged adipose-derived mesenchymal stem cell-derived small extracellular vesicles for bladder tissue engineering.
Tryptophan alleviates intestinal damage through regulating necroptosis and TLR4/NOD signaling pathways in pigs after lipopolysaccharide challenge.
Tryptophan alleviates lipopolysaccharide-induced liver injury and inflammation by modulating necroptosis and pyroptosis signaling pathways in piglets.
MiR-223-3p overexpressed adipose mesenchymal stem cell-derived exosomes promote wound healing via targeting MAPK10.
Caspase-9 inhibition triggers Hsp90-based chemotherapy-mediated tumor intrinsic innate sensing and enhances antitumor immunity.
Betaine ameliorates heat stress-induced apoptosis by affecting oxidative and endoplasmic reticulum stress in mouse Leydig cells.
Dysregulated Autophagy and Sarcomere Dysfunction in Patients With Heart Failure With Co-Occurrence of P63A and P380S BAG3 Variants.
Integrated bioinformatics and experiment revealed that cuproptosis is the potential common pathogenesis of three kinds of primary cardiomyopathy.
Mechanism of non-steroidal anti-androgen-induced liver injury: Reactive metabolites of flutamide and bicalutamide activate inflammasomes.
Exosomal PGAM1 promotes prostate cancer angiogenesis and metastasis by interacting with ACTG1.
Tumor-Associated Extracellular Microvesicles with Fluorine-Modified Carbohydrate Antigens Trigger a Stronger Antitumor Immune Response.
Effects of diazoxide on streptozotocin induced β cell damage via HSP70/HSP90/TLR4/AMPK signaling pathways.
Degradation of neurodegenerative disease-associated TDP-43 aggregates and oligomers via a proteolysis-targeting chimera.
Differentially Expressed microRNAs in Peritoneal Dialysis Effluent-Derived Exosomes from the Patients with Ultrafiltration Failure.
Antimicrobial Effect of Extracellular Vesicles Derived From Human Oral Mucosal Epithelial Cells on Candida albicans.
Exosome-transmitted miR-3124-5p promotes cholangiocarcinoma development via targeting GDF11.
PINK1-Dependent Mitophagy Reduced Endothelial Hyperpermeability and Cell Migration Capacity Under Simulated Microgravity.
HucMSC-Ex carrying miR-203a-3p.2 ameliorates colitis through the suppression of caspase11/4-induced macrophage pyroptosis.
Depletion of serum-derived exosomes aggravates heat stress-induced damage of bovine mammary epithelial cells.
c-Myc Sustains Pancreatic Cancer Cell Survival and mutp53 Stability through the Mevalonate Pathway.
Integrated Analysis of Transcriptome and microRNA Profile Reveals the Toxicity of Euphorbia Factors toward Human Colon Adenocarcinoma Cell Line Caco-2.
Defective Human SRP Induces Protein Quality Control and Triggers Stress Response.
Activation of the Chemokine Receptor CCR1 and Preferential Recruitment of Gαi Suppress RSV Replication: Implications for Developing Novel Respiratory Syncytial Virus Treatment Strategies.
Design, synthesis, and biological evaluation of novel dual inhibitors of heat shock protein 90/mammalian target of rapamycin (Hsp90/mTOR) against bladder cancer cells.
Exosome-derived FGD5-AS1 promotes tumor-associated macrophage M2 polarization-mediated pancreatic cancer cell proliferation and metastasis.
SIRT4 Expression Ameliorates the Detrimental Effect of Heat Stress via AMPK/mTOR Signaling Pathway in BMECs.
BAG3 protects chondrocytes against lumbar facet joint osteoarthritis by regulating autophagy and apoptosis.
Class 3 phosphoinositide 3-kinase promotes hepatic glucocorticoid receptor stability and transcriptional activity.
Triptolide promotes degradation of the unfolded gain-of-function Tp53(R175H/Y220C) mutant protein by initiating heat shock protein 70 transcription in non-small cell lung cancer.
Inhibition of the CDK2 and Cyclin A complex leads to autophagic degradation of CDK2 in cancer cells.
Engineered exosome as targeted lncRNA MEG3 delivery vehicles for osteosarcoma therapy.
In situ injectable hydrogel-loaded drugs induce anti-tumor immune responses in melanoma immunochemotherapy.
LONP1-mediated mitochondrial quality control safeguards metabolic shifts in heart development.
SUMO2-mediated SUMOylation of SH3GLB1 promotes ionizing radiation-induced hypertrophic cardiomyopathy through mitophagy activation.
CircEZH2/miR-133b/IGF2BP2 aggravates colorectal cancer progression via enhancing the stability of m(6)A-modified CREB1 mRNA.
Exosomal tRF-Leu-AAG-001 derived from mast cell as a potential non-invasive diagnostic biomarker for endometriosis.
Comparative transcriptome and Lipidome analyses suggest a lipid droplet-specific response to heat exposure of brown adipose tissue in normal and obese mice.
Single-cell analysis of human basal cell carcinoma reveals novel regulators of tumor growth and the tumor microenvironment.
Targeted Analysis of HSP70 Isoforms in Human Spermatozoa in the Context of Capacitation and Motility.
Mesenchymal Stem Cell-Derived Exosomes Attenuate Epithelial-Mesenchymal Transition of HK-2 Cells.
Eimeria falciformis secretes extracellular vesicles to modulate proinflammatory response during interaction with mouse intestinal epithelial cells.
miR-126-3p containing exosomes derived from human umbilical cord mesenchymal stem cells promote angiogenesis and attenuate ovarian granulosa cell apoptosis in a preclinical rat model of premature ovarian failure.
Magnetic hyperthermia induces effective and genuine immunogenic tumor cell death with respect to exogenous heating.
Monitoring Protein Import into the Endoplasmic Reticulum in Living Cells with Proximity Labeling.
BAG3 Regulation of RAB35 Mediates the Endosomal Sorting Complexes Required for Transport/Endolysosome Pathway and Tau Clearance.
Fine-Tuning of Cholesterol Homeostasis Controls Erythroid Differentiation.
PKM2 compensates for proteasome dysfunction by mediating the formation of the CHIP-HSP70-BAG3 complex and the aggregation of ubiquitinated proteins.
Pharmacological inhibition of BAG3-HSP70 with the proposed cancer therapeutic JG-98 is toxic for cardiomyocytes.
Zinc Protects against Heat Stress-Induced Apoptosis via the Inhibition of Endoplasmic Reticulum Stress in TM3 Leydig Cells.
Exosomes released from Sertoli cells contribute to the survival of Leydig cells through CCL20 in rats.
VPA and TSA Interrupt the Interplay between mutp53 and HSP70, Leading to CHK1 and RAD51 Down-Regulation and Sensitizing Pancreatic Cancer Cells to AZD2461 PARP Inhibitor.
Hypoxia-Preconditioned Extracellular Vesicles from Mesenchymal Stem Cells Improve Cartilage Repair in Osteoarthritis.
Exosomes derived from M2 type tumor-associated macrophages promote osimertinib resistance in non-small cell lung cancer through MSTRG.292666.16-miR-6836-5p-MAPK8IP3 axis.
Regorafenib and reactive metabolite of sunitinib activate inflammasomes: Implications for multi tyrosine kinase inhibitor-Iiduced immune related adverse events.
Exosomes derived from human umbilical cord mesenchymal stem cells protect against papain-induced emphysema by preventing apoptosis through activating VEGF-VEGFR2-mediated AKT and MEK/ERK pathways in rats.
Anserine and Carnosine Induce HSP70-Dependent H(2)S Formation in Endothelial Cells and Murine Kidney.
Effect of miR-143-3p from Extracellular Vesicles of Porcine Uterine Luminal Fluid on Porcine Trophoblast Cells.
Effects of the probiotic, Lactobacillus rhamnosus GG, on ulcer pathogenesis, HSP70 stress protein and nitric oxide levels in stress induced ulcer.
Human breast milk-derived exosomes through inhibiting AT II cell apoptosis to prevent bronchopulmonary dysplasia in rat lung.
Jianpi Huayu decoction inhibits the epithelial-mesenchymal transition of hepatocellular carcinoma cells by suppressing exosomal miR-23a-3p/Smad signaling.
The alleviative effect of thyroid hormone on cold stress-induced apotosis via HSP70 and mitochondrial apoptosis signal pathway in bovine Sertoli cells.
Nicotinamide mononucleotide alleviates heat stress-induced oxidative stress and apoptosis in BMECs through reducing mitochondrial damage and endoplasmic reticulum stress.
Distinct Gene Expression Patterns of Two Heat Shock Protein 70 Members During Development, Diapause, and Temperature Stress in the Freshwater Crustacean Daphnia magna.
Exosomes Isolated From Bone Marrow Mesenchymal Stem Cells Exert a Protective Effect on Osteoarthritis via lncRNA LYRM4-AS1-GRPR-miR-6515-5p.
The Formation of Melanocyte Apoptotic Bodies in Vitiligo and the Relocation of Vitiligo Autoantigens under Oxidative Stress.
Long Noncoding RNA RP11-115N4.1 Promotes Inflammatory Responses by Interacting With HNRNPH3 and Enhancing the Transcription of HSP70 in Unexplained Recurrent Spontaneous Abortion.
LncRNA FOXP4-AS1 Promotes Progression of Ewing Sarcoma and Is Associated With Immune Infiltrates.
Exogenous H(2) S prevents the nuclear translocation of PDC-E1 and inhibits vascular smooth muscle cell proliferation in the diabetic state.
Regulating immune memory and reversing tumor thermotolerance through a step-by-step starving-photothermal therapy.
Differential Expression Pattern of Goat Uterine Fluids Extracellular Vesicles miRNAs during Peri-Implantation.
SIRT3 protects bovine mammary epithelial cells from heat stress damage by activating the AMPK signaling pathway.
Repair of peripheral nerve defects by nerve grafts incorporated with extracellular vesicles from skin-derived precursor Schwann cells.
Melatonin potentiates the cytotoxic effect of Neratinib in HER2(+) breast cancer through promoting endocytosis and lysosomal degradation of HER2.
GADD45β stabilized by direct interaction with HSP72 ameliorates insulin resistance and lipid accumulation.
Dendrobium officinale Polysaccharide Alleviates Intestinal Inflammation by Promoting Small Extracellular Vesicle Packaging of miR-433-3p.
Lipidomic Profiling of Human Milk Derived Exosomes and Their Emerging Roles in the Prevention of Necrotizing Enterocolitis.
Dihydromyricetin attenuates heat stress-induced apoptosis in dairy cow mammary epithelial cells through suppressing mitochondrial dysfunction.
Cardiomyocyte contractile impairment in heart failure results from reduced BAG3-mediated sarcomeric protein turnover.
Cytokine Profile in Plasma Extracellular Vesicles of Parkinson's Disease and the Association with Cognitive Function.
Hypoxic tumor-derived exosomal circular RNA SETDB1 promotes invasive growth and EMT via the miR-7/Sp1 axis in lung adenocarcinoma.
Osteosarcoma-derived exosomal miR-501-3p promotes osteoclastogenesis and aggravates bone loss.
UBQLN2-HSP70 axis reduces poly-Gly-Ala aggregates and alleviates behavioral defects in the C9ORF72 animal model.
Dual roles of HSP70 chaperone HSPA1 in quality control of nascent and newly synthesized proteins.
Seminal exosomal miR-210-3p as a potential marker of Sertoli cell damage in Varicocele.
The Role and Mechanism of Exosomes from Umbilical Cord Mesenchymal Stem Cells in Inducing Osteogenesis and Preventing Osteoporosis.
The EGFR-HSF1 axis accelerates the tumorigenesis of pancreatic cancer.
Hsp90 is involved in pseudorabies virus virion assembly via stabilizing major capsid protein VP5.
Spermine Protects Cardiomyocytes from High Glucose-Induced Energy Disturbance by Targeting the CaSR-gp78-Ubiquitin Proteasome System.
Boron Attenuates Heat Stress-Induced Apoptosis by Inhibiting Endoplasmic Reticulum Stress in Mouse Granulosa Cells.
Small extracellular vesicle-mediated Hsp70 intercellular delivery enhances breast cancer adriamycin resistance.
Exosomes secreted from mesenchymal stem cells mediate the regeneration of endothelial cells treated with rapamycin by delivering pro-angiogenic microRNAs.
SKP-SC-EVs Mitigate Denervated Muscle Atrophy by Inhibiting Oxidative Stress and Inflammation and Improving Microcirculation.
A Modified Nucleoside 6-Thio-2'-Deoxyguanosine Exhibits Antitumor Activity in Gliomas.
Exosomal miR-193b-5p as a regulator of LPS-induced inflammation in dairy cow mammary epithelial cells.
Augmentation of the heat shock axis during exceptional longevity in Ames dwarf mice.
Recovery from heat shock requires the microRNA pathway in Caenorhabditis elegans.
A novel Hsp70 inhibitor specifically targeting the cancer-related Hsp70-Bim protein-protein interaction.
Amiodarone, Unlike Dronedarone, Activates Inflammasomes via Its Reactive Metabolites: Implications for Amiodarone Adverse Reactions.
Tubocapsenolide A targets C-terminal cysteine residues of HSP90 to exert the anti-tumor effect.
Adipose-derived stem cell exosomes facilitate rotator cuff repair by mediating tendon-derived stem cells.
Construction of Smart Nanotheranostic Platform Bi-Ag@PVP: Multimodal CT/PA Imaging-Guided PDT/PTT for Cancer Therapy.
S-allyl cysteine ameliorates heat stress-induced oxidative stress by activating Nrf2/HO-1 signaling pathway in BMECs.
Hepatitis A virus structural protein pX interacts with ALIX and promotes the secretion of virions and foreign proteins through exosome-like vesicles.
TRIM16 Promotes Osteogenic Differentiation of Human Periodontal Ligament Stem Cells by Modulating CHIP-Mediated Degradation of RUNX2.
An Eight-CircRNA Assessment Model for Predicting Biochemical Recurrence in Prostate Cancer.
Reactive metabolite of gefitinib activates inflammasomes: implications for gefitinib-induced idiosyncratic reaction.
Ultraviolet B irradiation enhances the secretion of exosomes by human primary melanocytes and changes their exosomal miRNA profile.
Hsp90 inhibitor HSP990 in very low dose upregulates EAAT2 and exerts potent antiepileptic activity.
Extracellular vesicle-mediated delivery of miR-101 inhibits lung metastasis in osteosarcoma.
circFMN2 Sponges miR-1238 to Promote the Expression of LIM-Homeobox Gene 2 in Prostate Cancer Cells.
Multifactorial Attenuation of the Murine Heat Shock Response With Age.
UBE2T-regulated H2AX monoubiquitination induces hepatocellular carcinoma radioresistance by facilitating CHK1 activation.
CDK5RAP3, a Novel Nucleoplasmic Shuttle, Deeply Regulates HSF1-Mediated Heat Stress Response and Protects Mammary Epithelial Cells from Heat Injury.
Small extracellular vesicle-bound vascular endothelial growth factor secreted by carcinoma-associated fibroblasts promotes angiogenesis in a bevacizumab-resistant manner.
Exogenous spermine attenuates rat diabetic cardiomyopathy via suppressing ROS-p53 mediated downregulation of calcium-sensitive receptor.
Liver-derived exosome-laden lncRNA MT1DP aggravates cadmium-induced nephrotoxicity.
Light-activated oxygen self-supplied starving therapy in near-infrared (NIR) window and adjuvant hyperthermia-induced tumor ablation with an augmented sensitivity.
Heat Stress Impairs the Physiological Responses and Regulates Genes Coding for Extracellular Exosomal Proteins in Rat.
Exosomes carrying ALDOA and ALDH3A1 from irradiated lung cancer cells enhance migration and invasion of recipients by accelerating glycolysis.
Tumor-Derived EV-Encapsulated miR-181b-5p Induces Angiogenesis to Foster Tumorigenesis and Metastasis of ESCC.
Various Anti-HSPA2 Antibodies Yield Different Results in Studies on Cancer-Related Functions of Heat Shock Protein A2.
Rosmarinic acid exerts a neuroprotective effect on spinal cord injury by suppressing oxidative stress and inflammation via modulating the Nrf2/HO-1 and TLR4/NF-κB pathways.
Circulating Exosomes From Lipopolysaccharide-Induced Ards Mice Trigger Endoplasmic Reticulum Stress in Lung Tissue.
CaCBL1 Acts as a Positive Regulator in Pepper Response to Ralstonia solanacearum.
LASP1 promotes proliferation, metastasis, invasion in head and neck squamous cell carcinoma and through direct interaction with HSPA1A.
Selenium Attenuates Chronic Heat Stress-Induced Apoptosis via the Inhibition of Endoplasmic Reticulum Stress in Mouse Granulosa Cells.
Enterovirus A71 capsid protein VP1 increases blood-brain barrier permeability and virus receptor vimentin on the brain endothelial cells.
Extracellular Vesicles from Hyperammonemic Rats Induce Neuroinflammation and Motor Incoordination in Control Rats.
Hepatic DNAJB9 Drives Anabolic Biasing to Reduce Steatosis and Obesity.
Extracellular vesicles from skin precursor-derived Schwann cells promote axonal outgrowth and regeneration of motoneurons via Akt/mTOR/p70S6K pathway.
Heat stress activates YAP/TAZ to induce the heat shock transcriptome.
Antagomirs targeting miR-142-5p attenuate pilocarpine-induced status epilepticus in mice.
Heat stress induces apoptosis through disruption of dynamic mitochondrial networks in dairy cow mammary epithelial cells.
Adipose-derived exosomes protect the pulmonary endothelial barrier in ventilator-induced lung injury by inhibiting the TRPV4/Ca(2+) signaling pathway.
Hypoxia preconditioned renal tubular epithelial cell-derived extracellular vesicles alleviate renal ischaemia-reperfusion injury mediated by the HIF-1α/Rab22 pathway and potentially affected by microRNAs.
(-)-Oleocanthal and (-)-oleocanthal-rich olive oils induce lysosomal membrane permeabilization in cancer cells.
The Capsid Protein VP1 of Coxsackievirus B Induces Cell Cycle Arrest by Up-Regulating Heat Shock Protein 70.
Mapping Interactome Networks of DNAJC11, a Novel Mitochondrial Protein Causing Neuromuscular Pathology in Mice.
Hepatitis B virus-regulated growth of liver cancer cells occurs through the microRNA-340-5p-activating transcription factor 7-heat shock protein A member 1B axis.
An acquired scaffolding function of the DNAJ-PKAc fusion contributes to oncogenic signaling in fibrolamellar carcinoma.
The circRNA circPTPRA suppresses epithelial-mesenchymal transitioning and metastasis of NSCLC cells by sponging miR-96-5p.
Bioinspired extracellular vesicles embedded with black phosphorus for molecular recognition-guided biomineralization.
Elevated levels of circulating ITIH4 are associated with hepatocellular carcinoma with nonalcoholic fatty liver disease: from pig model to human study.
The up-regulation of two identified wound healing specific proteins-HSP70 and lysozyme in regenerated Eisenia fetida through transcriptome analysis.
The exosome-like vesicles from osteoarthritic chondrocyte enhanced mature IL-1β production of macrophages and aggravated synovitis in osteoarthritis.
HMGB1-mediated differential response on hippocampal neurotransmitter disorder and neuroinflammation in adolescent male and female mice following cold exposure.
Exosomes from glioma cells induce a tumor-like phenotype in mesenchymal stem cells by activating glycolysis.
Design, synthesis and molecular mechanisms of novel dual inhibitors of heat shock protein 90/phosphoinositide 3-kinase alpha (Hsp90/PI3Kα) against cutaneous melanoma.
Necroptosis promotes autophagy-dependent upregulation of DAMP and results in immunosurveillance.
Inhibition of Heat Shock Protein 90 by 17-AAG Reduces Inflammation via P2X7 Receptor/NLRP3 Inflammasome Pathway and Increases Neurogenesis After Subarachnoid Hemorrhage in Mice.
Circulating exosomes contain protein biomarkers of metastatic non-small-cell lung cancer.
A proteomic approach reveals the differential protein expression in Drosophila melanogaster treated with red ginseng extract (Panax ginseng).
Curcumin inhibits liver cancer by inhibiting DAMP molecule HSP70 and TLR4 signaling.
Effects of Boron Supplementation on Expression of Hsp70 in the Spleen of African Ostrich.
Uncoupling of Metabolic Health from Longevity through Genetic Alteration of Adipose Tissue Lipid-Binding Proteins.
HSP90 recognizes the N-terminus of huntingtin involved in regulation of huntingtin aggregation by USP19.
Calcium sensing receptor protects high glucose-induced energy metabolism disorder via blocking gp78-ubiquitin proteasome pathway.
A comparative proteomic analysis reveals important proteins for the fertilization and early embryonic development of the oyster Crassostrea gigas.
Multifunctional WS(2) @Poly(ethylene imine) Nanoplatforms for Imaging Guided Gene-Photothermal Synergistic Therapy of Cancer.
Interferon α Induces the Apoptosis of Cervical Cancer HeLa Cells by Activating both the Intrinsic Mitochondrial Pathway and Endoplasmic Reticulum Stress-Induced Pathway.
Modification of the hTERT promoter by heat shock elements enhances the efficiency and specificity of cancer targeted gene therapy.
Changes in gene expression and content of Hsp70 and Hsp90 in striated muscles of mice after 30-day space flight on the biosatellite Bion-M1.
Identification of Hsf1 as a novel androgen receptor-regulated gene in mouse Sertoli cells.
Role of the nucleus tractus solitarii in the protection of pre-moxibustion on gastric mucosal lesions.
Effects of pre-moxibustion at Zusanli (ST36) on heat shock protein 70 expression in rats with gastric mucosal lesions after neurotomy.
Deng J, Liao C, Liu H, Tang X, Yang Y, Yang Y, Guo X, Zhang S, Xing K, Liao M, Tang C
Diabetes, metabolic syndrome and obesity : targets and therapy 2026;19:568066
Diabetes, metabolic syndrome and obesity : targets and therapy 2026;19:568066
Characteristics of Exosomes and Microbiota in the Decidua of Patients With Early Pregnancy Loss and Their Impact on Trophoblast Cells.
He F, Chen L, Lou J, Guo Y, Fan S, Yan T, Zhang Y
Molecular reproduction and development 2026 May;93(5):e70104
Molecular reproduction and development 2026 May;93(5):e70104
Seminal plasma extracellular vesicle-derived miR-296-3p targets PLA2G6 to enhance boar sperm motility by lowering Lys Phosphatidylcholine.
Zhao K, An Y, Zhang Y, Zhang J, Li H, Wang J, Yao Z, Wang T, Chen L, Chen X, Jin Y
Animal reproduction science 2026 May;288:108135
Animal reproduction science 2026 May;288:108135
Sparc-driven p62-dependent mitochondrial oxidative stress exacerbates myocardial ischemia and is attenuated by ginsenoside CK.
Liu Z, Su W, Li X, Guo L, Gao W
Free radical biology & medicine 2026 May;248:127-142
Free radical biology & medicine 2026 May;248:127-142
Combination of Hypoxia-Preconditioned ADSCs and Deferoxamine Can Speed Up the Healing of Diabetic Wounds by Promoting Angiogenesis and Regulating Macrophage Polarization.
Cai F, Chen W, Li Q, Chen S, Xu Y, Ren Y, Liu Y
Stem cell reviews and reports 2026 May;22(4):1811-1826
Stem cell reviews and reports 2026 May;22(4):1811-1826
TEAD1 Enhances Exosome Secretion and Promotes Exosome-Mediated Tissue Regeneration.
Pu Y, Wan Y, Shi W, Li B, Zhang H, Wu J, Li L, Guo W, Ding C, Yang W
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2026 May;13(25):e14104
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2026 May;13(25):e14104
Label-free streamlined photoacoustic image guidance facilitates NIR-II photoablation in models of melanoma lung metastases.
Xing W, Zhou Y, Haedicke K, Wang C, Vazquez-Prada KX, Wu H, Lin Z, Andreou C, Zhang Q, Shang K, Hu R, Kircher M, Ye X, Grimm J, Yang J
The Journal of clinical investigation 2026 May 1;136(9)
The Journal of clinical investigation 2026 May 1;136(9)
O-GlcNAcase promotes dendritic spine morphogenesis while downregulating their GluA2-containing AMPA receptors.
Han L, Galizia S, Pan J, Bhattacharjee M, Lagerlöf O
The Journal of biological chemistry 2026 Mar;302(3):111157
The Journal of biological chemistry 2026 Mar;302(3):111157
Decreased Glucose Metabolism and Declined Chaperones Are Unique Features Required for the Survival of Senescent Fibroblasts and Pyruvate Dehydrogenase Is a Potent Senolytic Target.
Zhang M, Hu Z, Piao S, Song Y, Jia Y, Liu J, Zhao N, Liu A, Fu S, Sun W, Xu H, Yang Y, Gygi SP, Zhou C
Aging cell 2026 Mar;25(3):e70434
Aging cell 2026 Mar;25(3):e70434
Novel Ce/Cu-modified black ceramics disrupted mitochondrial dysfunction and tricarboxylic acid cycle to induce cuproptosis in osteosarcoma cells.
Zhang R, Yin X, Xu Z, Yan Q
Biomaterials advances 2026 Mar;180:214576
Biomaterials advances 2026 Mar;180:214576
Extracellular vesicles-derived hybrid biomimetic nanoplatforms camouflaged Golgi apparatus-targeted aggregation induced emission photosensitizer to elicit pyroptosis and immunogenic cell death for efficient antitumor photoimmunotherapy.
Zhao X, Wu X, Shang R, Dou H, Chen H, Tan N
Acta pharmaceutica Sinica. B 2026 Mar;16(3):1696-1716
Acta pharmaceutica Sinica. B 2026 Mar;16(3):1696-1716
Copper-induced duodenal injury: Unveiling the dual role of cuproptosis and ferroptosis via the FDX1/GPX4 axis.
Zhang T, Dai X, Wang H, Hu Y, Gao X, Shu X, Cao H, Hu G, Xing C, Yang F
The Journal of nutritional biochemistry 2026 Mar;149:110181
The Journal of nutritional biochemistry 2026 Mar;149:110181
Mn(3)O(4)-potentiated bifunctional hydrogel for mild temperature-controlled tumor ablation and osteogenesis.
Zhao Y, Wang W, Liu M, Cai Y, Wang Y, Dong Y, Bai YK, Zhu J, Tay FR, Niu L
Bioactive materials 2026 Jan;55:391-409
Bioactive materials 2026 Jan;55:391-409
Identification of specific molecular markers in severe heatstroke using transcriptomics techniques.
Duan Z, Wang M, Zhou Y, Lu J, Ma Y, Xu Y, Deng J, Liu H, Chen J
International journal of legal medicine 2026 Jan;140(1):137-153
International journal of legal medicine 2026 Jan;140(1):137-153
Autocatalytic Signal Amplification via Orthogonal Recognition of Dual Proteins on the Surface of Serum Extracellular Vesicles for Precise Diagnosis of Prostate Cancer.
Tao J, Yang L, Chen J, Yue S, Song C, Liang C, Zhou J, Wang H
ACS sensors 2026 Jan 23;11(1):181-189
ACS sensors 2026 Jan 23;11(1):181-189
Neuroprotective Effects of Desert Milk Exosomes in LPS-Induced Cognitive Decline: Role of Microglial M2 Polarization and AMPK Signaling.
Li Y, Lu W, Qian W, Liao X, Wang P, Wang Y, Jiao W, Wang M, Zhao J, Yang J, Gao H, Li H
Nutrients 2026 Jan 19;18(2)
Nutrients 2026 Jan 19;18(2)
Amyloidogenic oligomers derived from TDP-43 LCD promote the condensation and phosphorylation of TDP-43.
Chen BP, Lee CC, He RY, Huang AC, Huang JR, Chan JCC, Huang JJ
Chemical science 2026 Jan 14;17(2):1210-1222
Chemical science 2026 Jan 14;17(2):1210-1222
The Whole Transcriptome Sequencing Profile of Serum-Derived Exosomes and Potential Pathophysiology of Age-Related Hearing Loss.
Yang G, Xie Z, Huang Y, Ke J, Tang Z, Chen Z, Kuang S, Li F, Luo H, Lai Q, Wang B, Zhang J, Yuan W
Diagnostics (Basel, Switzerland) 2026 Jan 12;16(2)
Diagnostics (Basel, Switzerland) 2026 Jan 12;16(2)
Combination of YAP inhibition and photodynamic therapy induces dual DNA damage and activates STING pathway to enhance immunotherapy in uveal melanoma.
Zhang S, Song M, Zhang J, Bai J, Cao X, Zhu L, Tian R
Redox biology 2026 Feb;89:103965
Redox biology 2026 Feb;89:103965
O-GlcNAc transferase couples nutrient availability to synaptic plasticity in paraventricular neurons to regulate satiety.
Pérez-Del-Pozo M, Bhattacharjee M, Tripathi A, Boafo T, Galizia S, Medini P, Druzin M, Lagerlöf O
The Journal of biological chemistry 2026 Feb;302(2):111124
The Journal of biological chemistry 2026 Feb;302(2):111124
Inhibition of dengue virus type 2 by hypericin mediated through viral envelope protein interaction.
Qi L, Tang M, Liu L, Cheng J, Xiao Q, Qiu J, Wu J
Virology journal 2026 Feb 6;23(1)
Virology journal 2026 Feb 6;23(1)
PDHA1-acetylation signaling suppresses cuproptosis to attenuate anti-androgen effect in prostate cancer.
Zhuang R, Zhou Q, Cheng B, Peng S, Xiong Z, Xie Z, Lin W, Su T, Li Z, Yao K, Wu Z, Huang H, Li K
Cell death & disease 2026 Feb 23;17(1)
Cell death & disease 2026 Feb 23;17(1)
Aryl hydrocarbon receptor-mediated transcriptional regulation of HSP70 exacerbates endoplasmic reticulum stress in lupus nephritis.
Wen M, Li J, Li Y, Hun M, Yang T, Meng Y, Liu L, Gong H, Yu Y, Zhang Z, Zhang Y, Dang X, Zhao M, He Q
Cell & bioscience 2026 Feb 22;16(1)
Cell & bioscience 2026 Feb 22;16(1)
Bmscs loaded exosome hydrogel promotes the repair of rotator cuff injury in rats in vivo.
Peng K, Wang S, Li J, Zhang J, Gao Y, Liu F, Guan C, Wang Y, Xu C
Scientific reports 2026 Feb 17;16(1)
Scientific reports 2026 Feb 17;16(1)
Neonatal inflammation induces ventral hippocampal microglial priming via epigenetic regulation of BAG3 to enhance adult depression susceptibility in mice.
Yang Y, Rong J, Zhang Y, Zhu Y, Wang X, Sha S, Yao J, Du J, Zhou R
Brain, behavior, and immunity 2026 Feb 16;135:106494
Brain, behavior, and immunity 2026 Feb 16;135:106494
An autonomous siRNA delivery system targeting NLRP3: implications in Parkinson's disease.
Lin L, Li Z, Su F, Huang H, Huang S, Chen W, Zheng J, Yu H, Li FZ, Du X, Li Y, Cai L, You H, Zhang Y, Pei Z
BMC medicine 2026 Feb 12;24(1)
BMC medicine 2026 Feb 12;24(1)
Near infrared enhanced palladium loaded siraitia grosvenorii carbon dots amplify mitophagy for acute lung injury immunotherapy.
Zhang J, Duan K, Liu Q, Chen S, Zheng H, Liu Y, Qian J, Yin M, Liu J, Li J, Li Z, Chen M, Huang X, Lin F, Gao M, Liao L
Bioactive materials 2026 Aug;62:1-16
Bioactive materials 2026 Aug;62:1-16
Dual-responsive PDA-HP hydrogel enables mitochondria-targeted mild photothermal therapy for spinal cord repair.
Li Y, Hu J, Ran B, Zhong H, Zhong N, Zhong Y, Fu X, Liu X, Wu G, Zhong Q, Li J
Materials today. Bio 2026 Apr;37:102783
Materials today. Bio 2026 Apr;37:102783
Light sensing enhances thermotolerance and competitive fitness via serotonergic signaling in an eyeless organism.
Zhou L, Liu Y
Cell research 2026 Apr;36(4):286-299
Cell research 2026 Apr;36(4):286-299
Multifunctional exosome-driven tumor immunotherapy sensitization: converting intratumoral bacteria into antitumor fighters.
Wei X, Zhang Y, Chen Y, Mo Z, Jiang B, Zhao J, Zhou S
Biomaterials 2026 Apr;327:123729
Biomaterials 2026 Apr;327:123729
Ascites circRNA ASCOR Drives Platinum Resistance of High-Grade Serous Ovarian Cancer by Facilitating RPA1 Nuclear Translocation.
Liu H, Zhu C, Yao X, Liu Y, Zhu J, Li Y, Xu H, Peng C, Shan G, Chen L, Zhou Y
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2026 Apr;13(23):e18922
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2026 Apr;13(23):e18922
Fungal Exosome-Like Nanoparticles from Huaier (Trametes robiniophila Murr.) Exhibit Antibreast Cancer Activity.
Zhang H, Liang XY, Yuan J, Kang H
Current developments in nutrition 2026 Apr;10(4):107657
Current developments in nutrition 2026 Apr;10(4):107657
Hsp70-Targeting Chimeras Enable Dual Proteasomal and Lysosomal Degradation of Intracellular and Extracellular Proteins.
Wang Z, Li P, Yin F, Zhang H, Wang S, Teng Y, Fan X, Wang K, Zhang Y, Lun H, Song T, Wang Z, Zhang Z
Journal of medicinal chemistry 2026 Apr 9;69(7):8417-8432
Journal of medicinal chemistry 2026 Apr 9;69(7):8417-8432
MiR-423-5p inhibition alleviates podocyte apoptosis in membranous nephropathy by targeting WT1/β-catenin axis.
Liu H, Zhang S, Zhao XN, Wang ZZ, Song JN, Liu SX
International urology and nephrology 2026 Apr 4;
International urology and nephrology 2026 Apr 4;
Identification and Screening of Lactate-Related Genes as Molecular Markers for Early Diagnosis of Steroid-Induced Osteonecrosis of the Femoral Head.
Wang Z, Dong S, Xu K, Tang X, Guo S, Jiang Y, Zhang Y, Li T
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2026 Apr 30;40(8):e71793
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2026 Apr 30;40(8):e71793
Remote mobilization of gut Tregs exosomes serves as nanoshuttles for targeted cardioprotection against ischemia/reperfusion injury by ginseng polysaccharides.
Li YY, Sun L, Wang Y, Yang HY, Xu DS, Zhong YZ, Zhang JH, Li Y, Pi FC, Li QL, Li ZR, Wang WT, Chen MT, Liu MN, Sun QD, Peng MM, Leung EL, Wu QB, Han YL, Liu L, Xie Y, Zhou YF, Zhou H
Pharmacological research 2026 Apr 28;228:108217
Pharmacological research 2026 Apr 28;228:108217
Hijacking client instability to selectively disrupt HSP90-driven glucocorticoid receptor activation.
Longhi E, Magni A, Torielli L, Lodigiani G, Carlessi E, Borsotti P, Doria F, Pirota V, Serapian SA, Arrigoni C, Lolicato M, Moroni E, Bergamaschi G, Taraboletti G, Colombo G
Pharmacological research 2026 Apr 27;228:108205
Pharmacological research 2026 Apr 27;228:108205
STI1 domains coordinate partitioning of UBQLN2 into stress-induced condensates.
Haws W, Dao TP, Varner B, Jones HB, Brown MP, Castañeda CA
bioRxiv : the preprint server for biology 2026 Apr 15;
bioRxiv : the preprint server for biology 2026 Apr 15;
Probiotic Bifidobacterium Confers Protection Against Heat Stroke Through Enhancement of Intestinal Barrier Function in Rats.
Cai G, Chen Y, Chen J, Zhang J, Cai J, Fan Q, Zhang Y, Tang Y, Huang J, Xia G, Wang C, Feng A, Nie X
Shock (Augusta, Ga.) 2026 Apr 1;65(4):686-699
Shock (Augusta, Ga.) 2026 Apr 1;65(4):686-699
Pathogenic mechanisms of amyotrophic lateral sclerosis-linked VAPB P56S mutation in the degeneration of corticospinal motor neurons.
Yang X, Zheng J, Wang X, Cai H, Yu J
Ageing and neurodegenerative diseases 2025;5(3)
Ageing and neurodegenerative diseases 2025;5(3)
Ultrasound-Targeted Nanobubbles Codelivering NKP-1339 and miR-142-5p for Synergistic Mitochondrial Immunogenic Cell Death and PD-L1 Inhibition in Cancer Therapy.
Zhang Y, Liu C, Jin S, Xie L, Xiao Q, Yao J
Biomaterials research 2025;29:0232
Biomaterials research 2025;29:0232
A Liquid Band-Aid with Mesenchymal Stem Cell-derived Exosomes for Wound Healing in Mice.
Zhang WY, Meng TJ, Hu J, Wen L, Du L, Cheng XC, Wang LS, Xiao FJ, Lu YX
Current pharmaceutical biotechnology 2025;26(6):911-922
Current pharmaceutical biotechnology 2025;26(6):911-922
Hyperthermia Inhibits Growth and Stemness of Esophageal Squamous Cell Carcinoma Cells Through Promoting Degradation of GLI1.
Qin H, Li X, Duan S, Li S, Ren M
Stem cells international 2025;2025:7249890
Stem cells international 2025;2025:7249890
Exosome-Delivered circFOXP1 Upregulates Autophagy and Promotes Hepatocellular Carcinoma Progression Through Its Encoded p196 Protein Targeting the KHDRBS3/ULK1 Axis.
Zhao P, Yin C, Liu R, Shao S, Ke W, Song Z
International journal of nanomedicine 2025;20:5247-5265
International journal of nanomedicine 2025;20:5247-5265
S-Adenosylmethionine Inhibits Plasminogen-Activating Inhibitor-1 and Protects Male Mice From FOLFOX-Induced Liver Injury.
Gangi A, Li TWH, Lim Y, Chandla S, Floris A, Khangholi A, Tomasi ML, Lu SC
Cellular and molecular gastroenterology and hepatology 2025;19(8):101513
Cellular and molecular gastroenterology and hepatology 2025;19(8):101513
Silk fibroin-collagen hydrogel loaded with IGF1-CESCs attenuates intervertebral disk degeneration by accelerating annulus fibrosus healing in rats.
Tian Z, Shen Z, Chen H, Zhao P
Frontiers in pharmacology 2025;16:1552174
Frontiers in pharmacology 2025;16:1552174
Hybrid NIR-responsive liposome/hydrogel platform mediating chemo-photothermal therapy of retinoblastoma enhanced by quercetin as an adjuvant.
Lin M, Liu X, Li J, Zou H, Wang J, Yan Z, Liu Y, Lyu Y, Feng N
Theranostics 2025;15(9):3995-4015
Theranostics 2025;15(9):3995-4015
High salt-induced osmotic stress differentially modulates hepatocellular and renal carcinoma cell proliferation.
Chen X, Rahman A, Kitada K, Wang Y, Nakajima Y, Liu C, Taoka R, Nishiyama A
Frontiers in oncology 2025;15:1693591
Frontiers in oncology 2025;15:1693591
Exosomes derived from miR-26a-5p-modified adipose mesenchymal stem cells improve wound healing by targeting MAP2K4.
Chen K, Ye W, Chi L, Xie S
Frontiers in bioengineering and biotechnology 2025;13:1662095
Frontiers in bioengineering and biotechnology 2025;13:1662095
Injectable exosome-reinforced konjac glucomannan composite hydrogel for repairing cartilage defect: activation of endogenous antioxidant pathways.
Ye C, Xu J, Wang Y, Ji M, Tao R, Han F, Zhou P
Regenerative biomaterials 2025;12:rbaf060
Regenerative biomaterials 2025;12:rbaf060
Unveiling the role of hexon-associated host proteins in fowl adenovirus serotype 4 replication.
Zhang X, Wang X, Zhao Y, Li S, Xu X
Frontiers in veterinary science 2025;12:1562872
Frontiers in veterinary science 2025;12:1562872
Brown adipocyte-derived exosomes in type 2 diabetes mellitus impair endothelial function via regulating intracellular calcium cycle.
Ruan X, Zhao W
Frontiers in cardiovascular medicine 2025;12:1546325
Frontiers in cardiovascular medicine 2025;12:1546325
LncRNA PVT1 promotes cuproptosis through transcriptional activation of FDX1 in colorectal cancer.
Ma J, Zhang Y, Sun Z, Guo H, Li X, Cai J, Zhang M, Chen M, Jiang J, Zhang L
Redox biology 2025 Sep;85:103722
Redox biology 2025 Sep;85:103722
Glyphosate targets FYN to regulate glycolysis and promote glioblastoma proliferation: A network toxicology study.
Ma A, Yang Z, He Q, Wang W, Ren H, Zhai C, Lan J
International journal of biological macromolecules 2025 Sep;321(Pt 3):146486
International journal of biological macromolecules 2025 Sep;321(Pt 3):146486
Bisphenol A promotes OSCC progression via GABBR1-mediated MAPK signaling and macrophage polarization: A network toxicology based study.
He Q, Ma A, Yang Z, Pang X, Li C, Diao J, Liu Y, Liu Q, Zhang Q, Dong Z, Zhang D
Ecotoxicology and environmental safety 2025 Sep 15;303:118835
Ecotoxicology and environmental safety 2025 Sep 15;303:118835
Oncolytic microgels with regulated antibody release augment tumor immunotherapy.
Guo J, Tan H, Chen W, Wang Y, Lin W, Zhong Z, Deng C
Journal of controlled release : official journal of the Controlled Release Society 2025 Sep 10;385:114003
Journal of controlled release : official journal of the Controlled Release Society 2025 Sep 10;385:114003
Iron overload exaggerates renal ischemia-reperfusion injury by promoting tubular cuproptosis via interrupting function of LIAS.
Chen S, Chen T, Xu C, Yu X, Shi J, Yang C, Zhu T
Redox biology 2025 Oct;86:103795
Redox biology 2025 Oct;86:103795
Plasma Exosomal circRNAs as Potential Biomarkers for Patients with Septic Shock-Induced Acute Kidney Injury.
Yang H, Li Y, Qu K, Zhang C, Ding M, Liu Y
Biotechnology and applied biochemistry 2025 Oct;72(5):1274-1283
Biotechnology and applied biochemistry 2025 Oct;72(5):1274-1283
Icariside II attenuates renal fibrosis through mTOR signaling modulation: an integrated approach combining network pharmacology, molecular dynamics, and in vitro validation.
Ding P, Pan JC, Tian WJ, Yang YJ, Feng YH, Gao G, Wu CL, Xin ZC
Translational andrology and urology 2025 Oct 31;14(10):3159-3180
Translational andrology and urology 2025 Oct 31;14(10):3159-3180
Novel E-F ring derivatives of aconitine scaffold as potent Hsp90 inhibitors for the treatment of colorectal cancer.
Zhang Y, Wang YP, Guo S, Li TT, Wang QY, Zhang X, Zheng YM, Wen YQ, Meng FH, Zhang TJ
European journal of medicinal chemistry 2025 Oct 15;296:117895
European journal of medicinal chemistry 2025 Oct 15;296:117895
PDLIM4 drives gastric cancer malignant progression and cisplatin resistance by inhibiting HSP70 ubiquitination and degradation via competitive interaction with STUB1.
Zhu C, Chen M, Fan L, Wang Y, Liu M, Kang G, Yin F, Tang H, He Y, Zhang S, Zeng L, Liu W, Yu K, Le A
Journal of nanobiotechnology 2025 Oct 11;23(1):661
Journal of nanobiotechnology 2025 Oct 11;23(1):661
Proteasomes suppress anticancer drug-induced cytotoxicity by inhibiting mitochondrial protein import and promoting ROS-BNIP3-mediated mitophagy.
Li L, Feng Y, Zhou J, Shao F, Peng Y, Zang S, Lei JH, Sun H, Tang D, Lin S, Chen J, Li H, Chu X, Qiao Y, Guo X, Wu K, Xu X, Deng CX
Drug resistance updates : reviews and commentaries in antimicrobial and anticancer chemotherapy 2025 Nov;83:101294
Drug resistance updates : reviews and commentaries in antimicrobial and anticancer chemotherapy 2025 Nov;83:101294
Heat shock protein HSPA1A promotes porcine epidemic diarrhea virus replication by targeting the viral RNA-dependent RNA polymerase.
Tian H, Hao P, Dong H, Wu B, Liu H, Du H, Wang K, Du Q, Jia S, Zhang M, Caicike A, Zhao Y, Zhao G, Tong D, Huang Y
International journal of biological macromolecules 2025 Nov;330(Pt 3):148267
International journal of biological macromolecules 2025 Nov;330(Pt 3):148267
Multi-modal microcarriers reprogram mitochondrial metabolism and activate efferocytosis in macrophages for osteoporotic bone repair.
Wang X, Liu C, Wang M, Yin B, Ge Y, Shu L, Sun H, Zhang W
Biomaterials 2025 Nov;322:123384
Biomaterials 2025 Nov;322:123384
Ferrum@albumin assembled nanoclusters inhibit NF-κB signaling pathway for NIR enhanced acute lung injury immunotherapy.
Guan X, Zou B, Jin W, Liu Y, Lan Y, Qian J, Luo J, Lei Y, Liang X, Zhang S, Xiao Y, Long Y, Qian C, Huang C, Tian W, Huang J, Lai Y, Gao M, Liao L
Acta pharmaceutica Sinica. B 2025 Nov;15(11):5891-5907
Acta pharmaceutica Sinica. B 2025 Nov;15(11):5891-5907
TRIM10β upregulation promotes microtubule destabilization and triggers proteotoxic stress.
Kim H, Shin W, Jeon B, Lee S, Park B
Cellular signalling 2025 Nov;135:112052
Cellular signalling 2025 Nov;135:112052
Dysregulated oxidative stress and lactate levels in treatment-resistant schizophrenia.
Fang Y, Zhang T, Xu K, Wang L, He J, Liao Y, Yuan N, Tang J
Brain, behavior, and immunity 2025 Nov;130:106111
Brain, behavior, and immunity 2025 Nov;130:106111
H(2)S-Activated Theranostic Platform for Precise Photoablation of Colorectal Tumors with NIR-II Dual-Modal Phototherapy.
Wu K, Sun L, Wu H, Zheng X, Xue Y, Zhang Z, Ma S, Zhao C, Liu Y, Gu X
Journal of medicinal chemistry 2025 Nov 27;68(22):24684-24700
Journal of medicinal chemistry 2025 Nov 27;68(22):24684-24700
Antihypertension and Improvement Effects of Hexapeptide APPLRP on Exosomes-Mediated Vascular Endothelial Inflammation in Spontaneously Hypertensive Rats.
Cai Q, Zhang T, Zhai K, Guo B, Gong Q, Yang Y, Ding YY, Gu Z, Song T
Journal of agricultural and food chemistry 2025 Nov 26;73(47):30458-30472
Journal of agricultural and food chemistry 2025 Nov 26;73(47):30458-30472
Overexpression of Hspa1b in the mouse hippocampus may be associated with major depressive disorder.
Zhao X, Shang Y, Zhu W, Wareesawetsuwan N, Zhu L, Li C, Chen J, Bi Y
Behavioral and brain functions : BBF 2025 Nov 26;21(1):42
Behavioral and brain functions : BBF 2025 Nov 26;21(1):42
Multi-cellular phenotypic dynamics during the progression of an immunocompetent breast cancer model.
Gsell L, Watson SS, Sutevski I, Massara M, Soukup K, Eroglu A, Mold JE, Cougnoux A, Joyce JA, Hausser J
iScience 2025 Nov 21;28(11):113808
iScience 2025 Nov 21;28(11):113808
Brigatinib activates inflammasomes: Implication for immune-related adverse events.
Noda T, Tanaka S, Maruta Y, Haruna M, Mizuguchi S, Fujimoto A, Urashima K, Kohda Y, Kato R
Toxicology and applied pharmacology 2025 May;498:117310
Toxicology and applied pharmacology 2025 May;498:117310
A kinase-independent Bcr-Abl function mediating an Hsp70-Bim protein-protein interaction in chronic myeloid leukemia.
Zhang H, Song T, Song Y, Hu Z, Soliman MES, Jiang M, Yin F, Yang Z, Wang Z, Zhang Z
International journal of biological macromolecules 2025 May;310(Pt 3):143249
International journal of biological macromolecules 2025 May;310(Pt 3):143249
Exosomes enriched with miR-31-3p from keratinocytes under oxidative stress promote vitiligo progression by destructing melanocytes and activating CD8(+) T cells.
Ma J, Zhou Y, Chen J, Guo S, Zhang W, Yi X, Du P, Wang Y, Chen J, Li S, Gao T, Li C, Jian Z
International journal of biological macromolecules 2025 May;310(Pt 1):143070
International journal of biological macromolecules 2025 May;310(Pt 1):143070
The depletion of TFAM and p-β-catenin(S552) in mitochondria in response to BoAHV-1 productive infection leads to decreased mitochondrial biogenesis.
Lin J, Fu X, Li X, Ding X, Li S, Fiorito F, Zhu L
Veterinary microbiology 2025 May;304:110454
Veterinary microbiology 2025 May;304:110454
Disruption of BAG3-mediated BACE1 stabilization alleviates neuropathology and memory deficits in a mouse model of Alzheimer's disease.
Xia L, Li J, Pang Y, Dai C, Xu M, Du Y, Tian Q, Yi L, Wu B, Chen M, Qiu Y, Cheng C, Wang YT, Song W, Dong Z
Science advances 2025 May 23;11(21):eadt7981
Science advances 2025 May 23;11(21):eadt7981
Asb10 accelerates pathological cardiac remodeling by stabilizing HSP70.
Lin K, Wei W, Chen S, Gong Y, Wang X, Wang M, Li R, Zhao Y, Xu S, Jin C, Jiang C, Fu G, Li Q
Cell death & disease 2025 May 22;16(1):409
Cell death & disease 2025 May 22;16(1):409
A label-free fluorescence aptasensor for salivary exosomes based on a nano-micro dual-scale signal amplification strategy.
Li LS, Chen XH, Pei Y, Xie XL, Wu CT, Cai S, Li J, Gong W
Talanta 2025 May 15;287:127638
Talanta 2025 May 15;287:127638
Breast cancer stem cell-derived exosomal lnc-PDGFD induces fibroblast-niche formation and promotes lung metastasis.
Tang T, Yang T, Xue H, Liu X, Yu J, Liang C, Li D, Xiang C, Zheng J, Wei L, Ma B
Oncogene 2025 Mar;44(9):601-617
Oncogene 2025 Mar;44(9):601-617
Longitudinal single-cell RNA sequencing reveals a heterogeneous response of plasma cells to colonic inflammation.
Wen X, Li W, Li S, Chen D, Zheng J, Wang X, Zhang C, Liu Y, Ning Y, Jia R, Li P, Ji M, Ji C, Li J, Guo W
International journal of biological macromolecules 2025 Mar;294:139307
International journal of biological macromolecules 2025 Mar;294:139307
Tumor-Resident Intracellular Bacteria Scavenger Activated In Situ Vaccines for Potent Cancer Photoimmunotherapy.
Lv B, Zhao Y, Li G, Jiang H, Zhang M, Li Z, Cao J
Advanced healthcare materials 2025 Mar;14(7):e2404271
Advanced healthcare materials 2025 Mar;14(7):e2404271
Identification of Potential Amblyomma americanum Antigens After Vaccination with Tick Extracellular Vesicles in White-Tailed Deer.
Oliva Chávez A, Gonzalez J, Harvey C, Ribeiro-Silva CS, Leal-Galvan B, Persinger KA, Durski S, Olafson PU, Johnson TL
Vaccines 2025 Mar 27;13(4)
Vaccines 2025 Mar 27;13(4)
Placental mesenchymal stem cell-derived exosomes treat endometrial injury in a rat model of intrauterine adhesions.
Liang L, Liu H, Wang S
Molecular genetics and genomics : MGG 2025 Mar 25;300(1):36
Molecular genetics and genomics : MGG 2025 Mar 25;300(1):36
Phenethyl isothiocyanate ameliorates liver injuries secondary to inflammatory bowel disease.
Ma C, Zhang L, Huang Q, Deng Q, Huang F, Xu J
Food & function 2025 Mar 17;16(6):2589-2597
Food & function 2025 Mar 17;16(6):2589-2597
E-jet 3D printed aligned nerve guidance conduits incorporated with decellularized extracellular matrix hydrogel encapsulating extracellular vesicles for peripheral nerve repair.
Fan N, Song D, Ding H, Yang H, Xu C, Wang C, Yang Y
Acta biomaterialia 2025 Mar 1;194:122-139
Acta biomaterialia 2025 Mar 1;194:122-139
Role of DLAT in cuproptosis and autophagy in hippocampal tissue of PTSD rats with high-voltage electrical burns.
Ge C, Zhao X, Zhang J, Li P, Hao J, Lu M, Li C, Ge L, Tu L, Zhang Q
Burns : journal of the International Society for Burn Injuries 2025 Jun;51(5):107519
Burns : journal of the International Society for Burn Injuries 2025 Jun;51(5):107519
Optically controllable nanoregulators enable tumor-specific pro-ferroptosis lipometabolic reprogramming for in-situ adjuvant-free vaccination.
Li M, Li Y, Yao X, Liu Y, Cai K, Yang H, Luo Z
Biomaterials 2025 Jun;317:123096
Biomaterials 2025 Jun;317:123096
Charge-reversed small extracellular vesicles from human adipose-derived mesenchymal stromal cells attenuate renal fibrosis postacute kidney injury by inhibiting epithelial-mesenchymal transition progression in SD rat model.
Ping W, Xu X, Jiang Y, Yang R, Xu L
Cytotherapy 2025 Jun;27(6):753-765
Cytotherapy 2025 Jun;27(6):753-765
Hsp70 incompletely disaggregates misfolded K488X-menin to promote tumourigenesis in a family with multiple endocrine neoplasia type 1.
Zeng Z, Zhang Q, Liang T, Xiong Y, Liu Z, Zhang J, Yang P, Yang J, Lu Q, Shen D, Tian H, Zhou Z, Fang W, Zhang M, Liu Q, Gao B, Wei Y, Zhou D
Cellular signalling 2025 Jun;130:111681
Cellular signalling 2025 Jun;130:111681
Diallyl Trisulfide From Garlic Regulates RAB18 Phase Separation to Inhibit Lipophagy and Induce Cuproptosis in Hepatic Stellate Cells for Antifibrotic Effects.
Tian H, Sun S, Qiu X, Wang J, Gao Y, Chen J, Han X, Bao Z, Guo X, Sun Y, Lin Y, Hu M, Zhang F, Zhang Z, Wang F, Zheng S, Shao J
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2025 Jun;12(21):e2415325
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2025 Jun;12(21):e2415325
Novel insights into human CRISP2: localization in reproductive tissues and sperm, and molecular characterization†.
Masai T, Delnatte A, Dendievel M, Nonclercq D, Frau A, Simon JF, Arcolia V, Wattiez R, Leroy B, Cuasnicu PS, Lybaert P, Hennebert E
Biology of reproduction 2025 Jun 15;112(6):1167-1184
Biology of reproduction 2025 Jun 15;112(6):1167-1184
miR166u -enriched Polygonatum sibiricum exosome-like nanoparticles alleviate colitis by improving intestinal barrier through the TLR4/AKT pathway.
Wei C, Chen Y, Chen J, Cao F, Cheng J, Pan C, Wei Y, Liu T, Jin Y, Yang G
International journal of biological macromolecules 2025 Jul;318(Pt 1):144802
International journal of biological macromolecules 2025 Jul;318(Pt 1):144802
Oxaliplatin accelerates immunogenic cell death by activating the cGAS/STING/TBK1/IRF5 pathway in gastric cancer.
Zhao S, Sun D, Yu H, Wang M, Xu B, Wang Y, Hu F, Wang X, Zhang J, Wang Y, Chai J
The FEBS journal 2025 Jul;292(14):3814-3828
The FEBS journal 2025 Jul;292(14):3814-3828
Kasumi-1 exosome plays a major T-cell immune evasion role in TP53-type acute leukemia.
Du Y, Fan Z, Li L, Xue Y, Zhao S
Immunobiology 2025 Jul;230(4):153102
Immunobiology 2025 Jul;230(4):153102
Small and Large Extracellular Vesicles From Human Preovulatory Follicular Fluid Display Distinct ncRNA Cargo Profiles and Differential Effects on KGN Granulosa Cells.
Varik I, Saretok KJ, Rosenberg K, Quintero I, Puhka M, Volkova N, Trošin A, Guazzi P, Velthut-Meikas A
Journal of extracellular vesicles 2025 Jul;14(7):e70119
Journal of extracellular vesicles 2025 Jul;14(7):e70119
Exosome-Functionalized Hydrogels Improve Cartilage Repair by Modulating BMSCs Migration and Differentiation.
Pei L, Wang Y, Ye M, Sun W, Zhang J, Gao P, Tao Z, Liu D, Jing J, Guan J
ACS applied materials & interfaces 2025 Jul 23;17(29):41729-41746
ACS applied materials & interfaces 2025 Jul 23;17(29):41729-41746
Endothelial cell-secreted bone targeting exosomes promote angiogenesis coupling with osteogenesis via the PERK-ATF4-CRELD2 pathway.
Pi Z, Wu Y, Wu J, Zhang T, Li P, Wang R
Stem cell research & therapy 2025 Jul 16;16(1):382
Stem cell research & therapy 2025 Jul 16;16(1):382
Ribosome association inhibits stress-induced gene mRNA localization to stress granules.
Helton NS, Dodd B, Moon SL
Genes & development 2025 Jul 1;39(13-14):826-848
Genes & development 2025 Jul 1;39(13-14):826-848
Mechanisms underlying the estradiol mediated protection of yak oviduct epithelial cells against ER-Ca(2+) imbalance.
Ye X, Wang M, Pan Y, Li T, Wang J, Zhao L, Zhang R, Cui Y, Yu S
BMC genomics 2025 Jul 1;26(1):613
BMC genomics 2025 Jul 1;26(1):613
Adipose tissue macrophages-derived exosomal MiR-500a-5p under high glucose promotes adipocytes inflammation by suppressing Nrf2 expression.
Li YZ, Tian Y, Yang C, Liu YF, Qu SL, Huang L, Zhang C
The international journal of biochemistry & cell biology 2025 Jan;178:106713
The international journal of biochemistry & cell biology 2025 Jan;178:106713
C9ORF72 poly-PR induces TDP-43 nuclear condensation via NEAT1 and is modulated by HSP70 activity.
Agnihotri D, Lee CC, Lu PC, He RY, Huang YA, Kuo HC, Huang JJ
Cell reports 2025 Jan 28;44(1):115173
Cell reports 2025 Jan 28;44(1):115173
Mechanism of hsa_circ_0069443 promoting early pregnancy loss through ALKBH5/FN1 axis in trophoblast cells.
Li BX, Wu MY, Wang ZH, Zhou DM, Li JQ, Lu BF, Lin XL, Zhao Y, Sheng XJ
iScience 2025 Jan 17;28(1):111608
iScience 2025 Jan 17;28(1):111608
The Expression Pattern and Functional Analysis of Extracellular Vesicle Long Non-Coding RNAs from Uterine Fluid During Implantation in Pig.
Shang Y, Zhang Q, Ding Y, Wang Y, Gu S, Zang X, Xu Z, Huang S, Li Z, Wu Z, Gu T, Hong L, Cai G
Animals : an open access journal from MDPI 2025 Jan 16;15(2)
Animals : an open access journal from MDPI 2025 Jan 16;15(2)
Enhancing inhibitory effect in SMMC-7721 hepatoma cells through combined treatment of gallic acid and hUC-MSCs-Exos.
Zhang Q, Han L, Luo X, Bao Y, Wang S, Li T, Huo J, Meng X
International immunopharmacology 2025 Jan 10;144:113704
International immunopharmacology 2025 Jan 10;144:113704
The new anti-angiogenesis perspective of rheumatoid arthritis with geniposide: Reducing the extracellular release of HSP70 in HUVECs.
Wei Y, Li Y, Shu Y, Gan PR, Zhu YL, Xu J, Jiang XM, Xia SL, Wang Y, Wu H
International immunopharmacology 2025 Jan 10;144:113645
International immunopharmacology 2025 Jan 10;144:113645
miRNA-21-5p is an important contributor to the promotion of injured peripheral nerve regeneration using hypoxia-pretreated bone marrow-derived neural crest cells.
Cong M, Hu JJ, Yu Y, Li XL, Sun XT, Wang LT, Wu X, Zhu LJ, Yang XJ, He QR, Ding F, Shi HY
Neural regeneration research 2025 Jan 1;20(1):277-290
Neural regeneration research 2025 Jan 1;20(1):277-290
AAV mediated carboxyl terminus of Hsp70 interacting protein overexpression mitigates the cognitive and pathological phenotypes of APP/PS1 mice.
Hu Z, Yang J, Zhang S, Li M, Zuo C, Mao C, Zhang Z, Tang M, Shi C, Xu Y
Neural regeneration research 2025 Jan 1;20(1):253-264
Neural regeneration research 2025 Jan 1;20(1):253-264
Angiogenesis-promoting effect of SKP-SC-EVs-derived miRNA-30a-5p in peripheral nerve regeneration by targeting LIF and ANGPT2.
Shen M, Ye X, Zhou Q, Zheng M, Du M, Wang L, Cong M, Liu C, Deng C, Xu Z, Wang Y, Li J, Feng M, Ye Y, Zhang S, Xu W, Lu Y, Kong J, Gong J, Xia Y, Gu J, Xie H, He Q, Zhang Q, Sun H, Liu X, Gong L, Yu M, Gu X, Zhao J, Zhang N, Ding F, Zhou S
The Journal of biological chemistry 2025 Feb;301(2):108146
The Journal of biological chemistry 2025 Feb;301(2):108146
Pyruvate Kinase M2-Responsive Release of Paclitaxel and Indoleamine 2,3-Dioxygenase Inhibitor for Immuno-Chemotherapy of Nonsmall Cell Lung Cancer.
Wu H, Sun X, Li K, Li J, Jiang H, Yan D, Lin Y, Ding Y, Lu Y, Zhu X, Chen X, Li X, Liang G, Xu H
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2025 Feb;12(7):e2409790
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2025 Feb;12(7):e2409790
hBMSC-EVs alleviate weightlessness-induced skeletal muscle atrophy by suppressing oxidative stress and inflammation.
Chang M, Liu R, Chen B, Xu J, Wang W, Ji Y, Gao Z, Liu B, Yao X, Sun H, Xu F, Shen Y
Stem cell research & therapy 2025 Feb 4;16(1):46
Stem cell research & therapy 2025 Feb 4;16(1):46
Chaihu Shugan San Exerts Antidepressant Effects by Regulating Glucocorticoid Metabolism in CUMS Rats and Network Pharmacology Provides Complementary Mechanistic Insights.
Xu Y, Han X, Zhu Y, Deng B, Li L, Du Y, Qin Y, Lv Y, Zhai X
ACS omega 2025 Feb 25;10(7):6780-6793
ACS omega 2025 Feb 25;10(7):6780-6793
Uterine-derived exosomes induce the M2 polarization of macrophages via miR-210-3p/ATP5D to promote endometriosis progression.
Chen S, Jiang Y, Chai X, Chen Z, Tian H, Liu M, Zhu T, ShangGuan W, Wu X
Life sciences 2025 Feb 15;363:123383
Life sciences 2025 Feb 15;363:123383
Methionine Modulates the Growth and Development of Heat-Stressed Dermal Papilla Cells via the Wnt/β-Catenin Signaling Pathway.
Li S, Wang X, Liu G, Li F
International journal of molecular sciences 2025 Feb 11;26(4)
International journal of molecular sciences 2025 Feb 11;26(4)
Low shear stress induces vascular endothelial cells apoptosis via miR-330 /SOD2 /HSP70 signaling pathway.
Li K, Wang S, Li J, Wang L, Zhang Q, Hou L, Yu X, Liu Z, Lv T, Shang L
Experimental cell research 2025 Feb 1;445(1):114410
Experimental cell research 2025 Feb 1;445(1):114410
3D-cultured DFAT spheroid-derived exosomes promote aged wound healing via modulation of the NF-κB/Serpine1 pathway.
Ma X, Wei W, Zeng H, Dong M
Tissue & cell 2025 Dec;97:103049
Tissue & cell 2025 Dec;97:103049
Sp3 ameliorated experimental autoimmune encephalomyelitis by triggering Socs3 in Th17 cells.
Li Y, Zhu M, Yang P, Chen D, Zhou D, Ren Y, Zhang Z, Ruan C, Da Y, Zhang R
Journal of advanced research 2025 Dec;78:239-255
Journal of advanced research 2025 Dec;78:239-255
Immunomodulatory copper-based polyphenol nanozyme for diabetic infectious wound healing via NIR amplified cuproptosis bacteriostat in synergy with ferroptosis inhibition anti-inflammation.
Gao H, Luo J, Chen X, Huang Y, Mo M, Luo Q, Liu Y, Zou B, Lei Y, Li Z, Huang L, Huang X, Liang P, Lin M, Huang J, Lu H, Huang H, Gao H, Zhang J, Lu J, Gao M
Bioactive materials 2025 Dec;54:759-776
Bioactive materials 2025 Dec;54:759-776
Jahn-Teller distortion-engineered self-propelled nanorobots for mitochondrial targeting and bioenergetic disruption in tumor therapy.
Luo T, Zhang M, Xu J, Yuan D, Yin B, Zhu Y, Yan S, Pan M, Mo D, Li X, Liang X, Qin Z, Deng H, Qian Z
Bioactive materials 2025 Dec;54:273-290
Bioactive materials 2025 Dec;54:273-290
Stage-specific TRIM10 expression regulates erythroid maturation.
Kim H, Shin W, Lee D, Jeon B, Kim Y, Shin D, Jeong H, Hong JY, Lee S, Park B
EMBO reports 2025 Dec;26(23):5982-6014
EMBO reports 2025 Dec;26(23):5982-6014
Overcoming ELDR-mediated cancer cell survival in vitro and in vivo via sphingomyelin-driven TRPML1 inactivation and TFEB suppression through lysosomal HSP70 targeting.
Chen H, Zhu M, Zhao Z, Jiang Y, Wang H, Liu Y, Chen Y, Li H, Xun C, Hui H
Pharmacological research 2025 Dec;222:108050
Pharmacological research 2025 Dec;222:108050
ERβ/circAHNAK Axis Inhibits USP10-FMR1 Deubiquitination to Prevent m⁶A-Mediated ADAM17 Decay and Promote Angiogenesis in Clear Cell Renal Cell Carcinoma.
Xu C, Zhang S, Liu Y, Lv J, Cao Y, Chen Y, Sun H, Zhang B, Dai S, Li J, Li X, Shi B, Sun Q, Zhu M, Gu J
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2025 Dec;12(48):e09654
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2025 Dec;12(48):e09654
TIA1-mediated stress granules promote neurodegeneration by sequestering HSP70 mRNA in C9orf72 mice.
Wei Y, Li D, Yang R, Liu Y, Luo X, Zhao W, Yang H, Chen Z, Shen C, Wang Y, Huang Z
Brain : a journal of neurology 2025 Dec 4;148(12):4482-4494
Brain : a journal of neurology 2025 Dec 4;148(12):4482-4494
A novel single-cell level evaluation method for corneal endothelial cell function.
Li D, Li Z, Duan H, Wang X, Lin Z, Dai K, Qi Q, Dong Y, Lin P, Su W, Wang S, Hu X, Pan X, Liu X, Zhou Q, Xie L
NPJ digital medicine 2025 Dec 22;8(1):791
NPJ digital medicine 2025 Dec 22;8(1):791
Upregulation of E3 ligase UBR2 in acetaldehyde-treated C2C12 myotubes and its potential involvement in fast-twitch muscle atrophy in alcohol-fed rats.
Shintani-Ishida K, Ikegaya H
Alcohol, clinical & experimental research 2025 Aug;49(8):1667-1677
Alcohol, clinical & experimental research 2025 Aug;49(8):1667-1677
Immunogenic cuproptosis in cancer immunotherapy via an in situ cuproptosis-inducing system.
Li J, Zhang G, Sun Z, Jiang M, Jia G, Liu H, Liu N, Shi L, Zhang L, Nie L, Zhang Y, Fu Y
Biomaterials 2025 Aug;319:123201
Biomaterials 2025 Aug;319:123201
Multifunctional targeted nanosystem based on aggregation-induced emission: Enhanced synergistic mild-photothermal chemotherapy of prostate cancer via downregulation of heat shock protein 70 under NIR-II imaging.
Gui B, Jiang N, Pu H, Zhong F, Huang X, Wang Z, Liu Q, Wang H, Zhou Y, Zhou Q, Deng Q
Colloids and surfaces. B, Biointerfaces 2025 Aug;252:114667
Colloids and surfaces. B, Biointerfaces 2025 Aug;252:114667
The BAG3-HSP70-CHIP axis controls the degradation of TGFBR2 in cardiac fibroblasts.
Morsink MAJ, Watkins JM, Zhu K, Zhang X, Luo LJ, Fine BM, Wang BZ, Vunjak-Novakovic G
Journal of molecular and cellular cardiology 2025 Aug;205:13-23
Journal of molecular and cellular cardiology 2025 Aug;205:13-23
Vascular Smooth Muscle-Secreted Exosomal X26nt Impedes Atherosclerosis Progression via the c-FOS/XBP1/SOD1 Axis.
Zhang Z, Liu D, Zheng Y, Liu Y, Cheng X, Chang Y, Liang X, Hu X, Gao W
Immunity, inflammation and disease 2025 Aug;13(8):e70251
Immunity, inflammation and disease 2025 Aug;13(8):e70251
Episodic transport of protein aggregates achieves a positive size selectivity in aggresome formation.
Fang R, Bai L, Verheijen BM, Li B, Dong K, Paulo JA, Zhou M, Chu YC, Song Y, Sherman MY, Gygi S, Field CM, Mitchison TJ, Lu Y
Nature communications 2025 Aug 22;16(1):7852
Nature communications 2025 Aug 22;16(1):7852
MRO/HNRNPU/CCL5 feedback loop amplifies M2 macrophage and breast cancer cell crosstalk to drive progression.
Zeng Z, Bao X, Lei S, Tang W, Tai H, Wang L, Li D, Liu S, Chen T
Journal of translational medicine 2025 Aug 15;23(1):920
Journal of translational medicine 2025 Aug 15;23(1):920
A hollow-tube-like hydrospongel for multimodal therapy of advanced colorectal cancer.
Wu T, Li T, Zhang C, Tian Y, Li H, He Y, Yan X, Gong T, Zhao J, Wang Z
Nature communications 2025 Aug 12;16(1):7464
Nature communications 2025 Aug 12;16(1):7464
Bone marrow mesenchymal stem cell derived exosomal miR-361-5p reversed the effect of bortezomib on multiple myeloma.
Lin T, Zhang Y, Hu Z, Liu S
Technology and health care : official journal of the European Society for Engineering and Medicine 2025 Aug 1;:9287329251350918
Technology and health care : official journal of the European Society for Engineering and Medicine 2025 Aug 1;:9287329251350918
Self-propelling intelligent nanomotor: A dual-action photothermal and starvation strategy for targeted deep tumor destruction.
Mei L, Ding Q, Xie Y, Liu H, Li H, Kim E, Shen X, Zhang Y, Zhang S, Kim JS
Biomaterials 2025 Apr;315:122968
Biomaterials 2025 Apr;315:122968
Reprogramming Lung Redox Homeostasis by NIR Driven Ultra-Small Pd Loaded Covalent Organic Framework Inhibits NF-κB Pathway for Acute Lung Injury Immunotherapy.
Lei D, Liao L, Qin T, Guan X, Duan K, Gao Z, Jin W, Yin M, Zhang K, Liu Y, Chen Y, Gao H, Li J, Huang F, Liu W, Xia C, Wang B, Huang H, Lv S, Zhi Q, Huang J, Gao M, Lu J
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2025 Apr;12(14):e2413697
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2025 Apr;12(14):e2413697
Targeted Regulation of HSP70 by the ARP2/3 Complex in Mammary Epithelial Cells and Its Impact on Host Cell Apoptosis.
Yang T, Fang B, Chen Y, Bao D, Zhang J, Liu P, Duan Z, He Y, Zhao X, Zhang QW, Dong WT, Zhang Y
Biomolecules 2025 Apr 7;15(4)
Biomolecules 2025 Apr 7;15(4)
Chlorophyllin exerts synergistic anti-tumor effect with gemcitabine in pancreatic cancer by inducing cuproptosis.
Ren J, Su T, Ding J, Chen F, Mo J, Li J, Wang Z, Han L, Wu Z, Wu S
Molecular medicine (Cambridge, Mass.) 2025 Apr 4;31(1):126
Molecular medicine (Cambridge, Mass.) 2025 Apr 4;31(1):126
Estradiol Alleviates Elevated Temperature-Induced Damage in Yak Oviductal Epithelial Cells by Maintaining Endoplasmic Reticulum Calcium Homeostasis.
Ye X, Wang M, Qiu S, Pan Y, Cui Y, Yu S
Animals : an open access journal from MDPI 2025 Apr 30;15(9)
Animals : an open access journal from MDPI 2025 Apr 30;15(9)
Development of Novel PRMT7 Inhibitors for the Treatment of Prostate Cancer.
Li J, Sun C, Zhang Y, Ding J, Yao P, Shen H, Shi Z, Wang W, Zhu Y, Kuang W, Tavus A, Wang L, Yuan K, Wang X, Yang P
Journal of medicinal chemistry 2025 Apr 24;68(8):8244-8268
Journal of medicinal chemistry 2025 Apr 24;68(8):8244-8268
Neural-induced human adipose tissue-derived stem cell secretome exerts neuroprotection against rotenone-induced Parkinson's disease in rats.
Ramalingam M, Jang S, Hwang J, Cho HH, Kim BC, Jeong HS
Stem cell research & therapy 2025 Apr 20;16(1):193
Stem cell research & therapy 2025 Apr 20;16(1):193
In vitro study on the promotion of osteogenic differentiation by mitochondrial-derived vesicles through activation of inflammation and reprogramming of metabolic pathways.
Pan C, Cheng C, Zhong S, Li S, Tan W, Yao Y
Journal of orthopaedic surgery and research 2025 Apr 17;20(1):388
Journal of orthopaedic surgery and research 2025 Apr 17;20(1):388
Canolol Alleviates Ethanol-Induced Gastric Ulcer by Inhibiting p38 MAPK/NF-κB/NLRP3 Pathway.
Ma C, Zhang L, Huang Q, Deng Q, Huang F, Xu J
Journal of agricultural and food chemistry 2025 Apr 16;73(15):9103-9111
Journal of agricultural and food chemistry 2025 Apr 16;73(15):9103-9111
An unconventional autophagic pathway that inhibits ATP secretion during apoptotic cell death.
Terraza-Silvestre E, Villamuera R, Bandera-Linero J, Letek M, Oña-Sánchez D, Ramón-Barros C, Moyano-Jimeno C, Pimentel-Muiños FX
Nature communications 2025 Apr 10;16(1):3409
Nature communications 2025 Apr 10;16(1):3409
UCH-L1 Inhibitor Alleviates Nerve Damage Caused by Moyamoya Disease.
Xu M, Zhao X, Zhao J, Tan Z, Zhang C, Huang Y, Zhong H, Guo M, Zhang C, Ye P, Zheng W
Applied bionics and biomechanics 2024;2024:2550642
Applied bionics and biomechanics 2024;2024:2550642
Immunomodulatory effect of PLGA-encapsulated mesenchymal stem cells-derived exosomes for the treatment of allergic rhinitis.
Shahzad KA, Wang Z, Li X, Li J, Xu M, Tan F
Frontiers in immunology 2024;15:1429442
Frontiers in immunology 2024;15:1429442
Heat acclimation with probiotics-based ORS supplementation alleviates heat stroke-induced multiple organ dysfunction via improving intestinal thermotolerance and modulating gut microbiota in rats.
Li L, Chen J, Wang Y, Pei Y, Ren L, Dai X, Li J, Ma J, Wang M, Chang W, Chen J, Song Q, Xu S
Frontiers in microbiology 2024;15:1385333
Frontiers in microbiology 2024;15:1385333
Single cell analyses reveal the PD-1 blockade response-related immune features in hepatocellular carcinoma.
Li Y, Li F, Xu L, Shi X, Xue H, Liu J, Bai S, Wu Y, Yang Z, Xue F, Xia Y, Dong H, Shen F, Wang K
Theranostics 2024;14(9):3526-3547
Theranostics 2024;14(9):3526-3547
mRNA expression profiles in muscle-derived extracellular vesicles of Large White and wild boar piglets reveal their potential roles in immunity and muscle phenotype.
Yu N, Chang X, Hu J, Li J, Ma J, Huang L
Frontiers in veterinary science 2024;11:1452704
Frontiers in veterinary science 2024;11:1452704
Polystyrene nanoparticles trigger aberrant condensation of TDP-43 and amyotrophic lateral sclerosis-like symptoms.
Sun H, Yang B, Li Q, Zhu X, Song E, Liu C, Song Y, Jiang G
Nature nanotechnology 2024 Sep;19(9):1354-1365
Nature nanotechnology 2024 Sep;19(9):1354-1365
Discovery of novel quinoline scaffold selective estrogen receptor degraders (SERDs) for treatment of ER positive breast cancer with enhanced antiproliferative bioactivity through immunogenic cell death (ICD) effects.
Lu Y, Liang Z, Liu L, Zhou Y, Liu C, Zhao Z, Zheng T, Du Q, Liu W
European journal of medicinal chemistry 2024 Sep 5;275:116534
European journal of medicinal chemistry 2024 Sep 5;275:116534
Umbilical cord blood-derived exosomes attenuate dopaminergic neuron damage of Parkinson's disease mouse model.
Ye J, Sun X, Jiang Q, Gui J, Feng S, Qin B, Xie L, Guo A, Dong J, Sang M
Journal of nanobiotechnology 2024 Sep 14;22(1):567
Journal of nanobiotechnology 2024 Sep 14;22(1):567
Hypoxic microenvironment promotes diabetic wound healing by polarizing macrophages to the M2 phenotype in vivo.
Cai F, Wang P, Yuan M, Chen W, Liu Y
Journal of molecular histology 2024 Oct;55(5):967-976
Journal of molecular histology 2024 Oct;55(5):967-976
Biomimetic nanocomplex based corneal neovascularization theranostics.
Ye J, Cheng Y, Wen X, Han Y, Wei X, Wu Y, Chen C, Su M, Cai S, Pan J, Liu G, Chu C
Journal of controlled release : official journal of the Controlled Release Society 2024 Oct;374:50-60
Journal of controlled release : official journal of the Controlled Release Society 2024 Oct;374:50-60
Novel Insights Into DLAT's Role in Alzheimer's Disease-Related Copper Toxicity Through Microglial Exosome Dynamics.
Ma X, Sun Y, Li C, Wang M, Zang Q, Zhang X, Wang F, Niu Y, Hua J
CNS neuroscience & therapeutics 2024 Oct;30(10):e70064
CNS neuroscience & therapeutics 2024 Oct;30(10):e70064
High temperature ameliorates high-fat diet-induced obesity by promoting ceramide breakdown in skeletal muscle tissue.
Wang Q, Chen L, Zhang J, Liu Y, Jin Y, Wu J, Ren Z
Life metabolism 2024 Oct;3(5):loae012
Life metabolism 2024 Oct;3(5):loae012
CaMKII suppresses proteotoxicity by phosphorylating BAG3 in response to proteasomal dysfunction.
Zhang C, Xu H, Tang Q, Duan Y, Xia H, Huang H, Ye D, Bi F
EMBO reports 2024 Oct;25(10):4488-4514
EMBO reports 2024 Oct;25(10):4488-4514
Short Repeat Ribonucleic Acid Reduces Cytotoxicity by Preventing the Aggregation of TDP-43 and Its 25 KDa Carboxy-Terminal Fragment.
Fujimoto A, Kinjo M, Kitamura A
JACS Au 2024 Oct 28;4(10):3896-3909
JACS Au 2024 Oct 28;4(10):3896-3909
S-RBD-modified and miR-486-5p-engineered exosomes derived from mesenchymal stem cells suppress ferroptosis and alleviate radiation-induced lung injury and long-term pulmonary fibrosis.
Zhang WY, Wen L, Du L, Liu TT, Sun Y, Chen YZ, Lu YX, Cheng XC, Sun HY, Xiao FJ, Wang LS
Journal of nanobiotechnology 2024 Oct 26;22(1):662
Journal of nanobiotechnology 2024 Oct 26;22(1):662
m6A-modified exosome-derived circHIF1α binding to KH domain of IGF2BP3 mediates DNA damage and arrests G1/S transition phase to resists bacterial infection in bacteremia.
Yu J, Gao Y, Liu F, Zhang Y, Li J, Ding L, Ren S, Yang J, Jiao J, Feng G, Chen Z, Sun W, Wu J
Journal of nanobiotechnology 2024 Oct 24;22(1):654
Journal of nanobiotechnology 2024 Oct 24;22(1):654
Tumor Microenvironment-Responsive Biodegradable Nanomedicine for Self-Enhanced Synergistic Chemo-, Photothermal, and Chemodynamic Therapy.
Tang HX, He ZH, Liu CG, Zheng XK, Zhang ZJ
ACS applied materials & interfaces 2024 Oct 2;16(39):52023-52035
ACS applied materials & interfaces 2024 Oct 2;16(39):52023-52035
Comparative investigation of exosome extraction from rat bone marrow mesenchymal stem cells using three different methodologies.
Wang N, Yin M, Yu J, Zhang J, Pan X
Electrophoresis 2024 Nov;45(21-22):2045-2053
Electrophoresis 2024 Nov;45(21-22):2045-2053
Caspase-2 is a condensate-mediated deubiquitinase in protein quality control.
Ge Y, Zhou L, Fu Y, He L, Chen Y, Li D, Xie Y, Yang J, Wu H, Dai H, Peng Z, Zhang Y, Yi S, Wu B, Zhang X, Zhang Y, Ying W, Cui CP, Liu CH, Zhang L
Nature cell biology 2024 Nov;26(11):1943-1957
Nature cell biology 2024 Nov;26(11):1943-1957
Mucosal Exosome Proteomics of Hybrid Grouper Epinephelus fuscoguttatus♀ × E. lanceolatus♂ Infected by Pseudomonas plecoglossicida.
Yang D, Ma X, Zhong S, Guo J, Cheng D, Chen X, Huang T, Huang L, Qiao Y, Pengsakul T
Animals : an open access journal from MDPI 2024 Nov 25;14(23)
Animals : an open access journal from MDPI 2024 Nov 25;14(23)
Exosome-derived circ-001422 promotes tumor-associated macrophage M2 polarization to accelerate the progression of glioma.
Cao W, Zeng Z, Sun J, Chen Y, Kuang F, Luo S, Lan J, Lei S
Communications biology 2024 Nov 13;7(1):1504
Communications biology 2024 Nov 13;7(1):1504
Analysis of the effects of M2 macrophage-derived PDE4C on the prognosis, metastasis and immunotherapy benefit of osteosarcoma.
Pan F, Pan R, Hu R, Zhang H, Lei S, Zhang L, Zhou C, Zeng Z, Tian X, Xie Q
Journal of cellular and molecular medicine 2024 May;28(10):e18395
Journal of cellular and molecular medicine 2024 May;28(10):e18395
Reduction of Filamin C Results in Altered Proteostasis, Cardiomyopathy, and Arrhythmias.
Ohiri JC, Dellefave-Castillo L, Tomar G, Wilsbacher L, Choudhury L, Barefield DY, Fullenkamp D, Gacita AM, Monroe TO, Pesce L, Blancard M, Vaught L, George AL Jr, Demonbreun AR, Puckelwartz MJ, McNally EM
Journal of the American Heart Association 2024 May 21;13(10):e030467
Journal of the American Heart Association 2024 May 21;13(10):e030467
An ATP13A1-assisted topogenesis pathway for folding multi-spanning membrane proteins.
Ji J, Cui MK, Zou R, Wu MZ, Ge MX, Li J, Zhang ZR
Molecular cell 2024 May 16;84(10):1917-1931.e15
Molecular cell 2024 May 16;84(10):1917-1931.e15
A combination of PD-L1-targeted IL-15 mRNA nanotherapy and ultrasound-targeted microbubble destruction for tumor immunotherapy.
Wang X, Li F, Zhang J, Guo L, Shang M, Sun X, Xiao S, Shi D, Meng D, Zhao Y, Jiang C, Li J
Journal of controlled release : official journal of the Controlled Release Society 2024 Mar;367:45-60
Journal of controlled release : official journal of the Controlled Release Society 2024 Mar;367:45-60
Selenomethionine alleviates chronic heat stress-induced breast muscle injury and poor meat quality in broilers via relieving mitochondrial dysfunction and endoplasmic reticulum stress.
Jing J, Wang J, Xiang X, Yin S, Tang J, Wang L, Jia G, Liu G, Chen X, Tian G, Cai J, Kang B, Che L, Zhao H
Animal nutrition (Zhongguo xu mu shou yi xue hui) 2024 Mar;16:363-375
Animal nutrition (Zhongguo xu mu shou yi xue hui) 2024 Mar;16:363-375
Bi(2)S(3)/Ti(3)C(2)-TPP nano-heterostructures induced by near-infrared for photodynamic therapy combined with photothermal therapy on hypoxic tumors.
Jiang H, Sun J, Liu F, Zhao Y, Chen X, Dai C, Wen Z
Journal of nanobiotechnology 2024 Mar 20;22(1):123
Journal of nanobiotechnology 2024 Mar 20;22(1):123
L-Theanine alleviates heat stress through modulation of gut microbiota and immunity.
Liu S, Wang B, Lin L, Xu W, Gong ZH, Xiao WJ
Journal of the science of food and agriculture 2024 Mar 15;104(4):2059-2072
Journal of the science of food and agriculture 2024 Mar 15;104(4):2059-2072
Plasma extracellular vesicle synaptic proteins as biomarkers of clinical progression in patients with Parkinson's disease.
Hong CT, Chung CC, Yu RC, Chan L
eLife 2024 Mar 14;12
eLife 2024 Mar 14;12
The mitochondrial UPR induced by ATF5 attenuates intervertebral disc degeneration via cooperating with mitophagy.
Xu WN, Zheng HL, Yang RZ, Sun YF, Peng BR, Liu C, Song J, Jiang SD, Zhu LX
Cell biology and toxicology 2024 Mar 13;40(1):16
Cell biology and toxicology 2024 Mar 13;40(1):16
Ponicidin-induced conformational changes of HSP90 regulates the MAPK pathway to relieve ulcerative colitis.
Zhang X, Xu Y, Fan M, Lv X, Long J, Yang R, Zhang R, Liu Z, Gu J, Wu P, Wang C
Journal of ethnopharmacology 2024 Mar 1;321:117483
Journal of ethnopharmacology 2024 Mar 1;321:117483
Reactive metabolite of trovafloxacin activates inflammasomes: Implications for trovafloxacin-induced liver injury.
Tanaka S, Noda T, Urashima K, Ijiri Y, Kohda Y, Kato R
Journal of applied toxicology : JAT 2024 Jun;44(6):846-852
Journal of applied toxicology : JAT 2024 Jun;44(6):846-852
Exosomes from adipose-derived stem cells regulate macrophage polarization and accelerate diabetic wound healing via the circ-Rps5/miR-124-3p axis.
Yin D, Shen G
Immunity, inflammation and disease 2024 Jun;12(6):e1274
Immunity, inflammation and disease 2024 Jun;12(6):e1274
NIR triggered polydopamine coated cerium dioxide nanozyme for ameliorating acute lung injury via enhanced ROS scavenging.
Yin M, Lei D, Liu Y, Qin T, Gao H, Lv W, Liu Q, Qin L, Jin W, Chen Y, Liang H, Wang B, Gao M, Zhang J, Lu J
Journal of nanobiotechnology 2024 Jun 8;22(1):321
Journal of nanobiotechnology 2024 Jun 8;22(1):321
Deciphering ER stress-unfolded protein response relationship by visualizing unfolded proteins in the ER.
Xu F, Wang L
Cell reports 2024 Jun 25;43(6):114358
Cell reports 2024 Jun 25;43(6):114358
CGG repeats in the human FMR1 gene regulate mRNA localization and cellular stress in developing neurons.
Sirois CL, Guo Y, Li M, Wolkoff NE, Korabelnikov T, Sandoval S, Lee J, Shen M, Contractor A, Sousa AMM, Bhattacharyya A, Zhao X
Cell reports 2024 Jun 25;43(6):114330
Cell reports 2024 Jun 25;43(6):114330
Ultrashort wave diathermy inhibits pulmonary inflammation in mice with acute lung injury in a HSP70 independent way: a pilot study.
Yang X, Li K, Li M, Chen C, Yang X, Li J, Zhang H
Molecular biology reports 2024 Jun 14;51(1):750
Molecular biology reports 2024 Jun 14;51(1):750
Engineered Luminescent Oncolytic Vaccinia Virus Activation of Photodynamic-Immune Combination Therapy for Colorectal Cancer.
Ye LY, Li YS, Ge T, Liu LC, Si JX, Yang X, Fan WJ, Liu XZ, Zhang YN, Wang JW, Wang SB, Zou H, Zheng YL, Jin KT, Mao ZW, Cai Y, Mou XZ
Advanced healthcare materials 2024 Jul;13(17):e2304136
Advanced healthcare materials 2024 Jul;13(17):e2304136
Effects of spinal cord injury associated exosomes delivered tRF-41 on the progression of spinal cord injury progression.
Cai H, Zhang Y, Meng F, Li Y
Genomics 2024 Jul;116(4):110885
Genomics 2024 Jul;116(4):110885
Nano-Se exhibits limited protective effect against heat stress induced poor breast muscle meat quality of broilers compared with other selenium sources.
Jing J, Wang J, Wu Q, Yin S, He Z, Tang J, Jia G, Liu G, Chen X, Tian G, Cai J, Kang B, Che L, Zhao H
Journal of animal science and biotechnology 2024 Jul 8;15(1):95
Journal of animal science and biotechnology 2024 Jul 8;15(1):95
Enhanced therapeutic impact of Shikonin-encapsulated exosomes in the inhibition of colorectal cancer progression.
Lu Y, Zhou H, Han C, Gong Y, Li Y, Xia Y, Liang B, Yang H, Wang Z
Nanotechnology 2024 Jul 23;35(41)
Nanotechnology 2024 Jul 23;35(41)
Exploring and validating heating dynamics in a radio-frequency electromagnetic field-based resonant chamber for mouse hyperthermia research.
Jiao L, Zhang T, Gao P, Zhou C, Mei X, Zhang W, Lu Y, Zhang L, Zhou Z, Yu Z, He M
Electromagnetic biology and medicine 2024 Jul 2;43(3):164-175
Electromagnetic biology and medicine 2024 Jul 2;43(3):164-175
Extracellular vesicles separated from goat milk by differential centrifugation coupled with sodium citrate pretreatments.
Fu S, Zhu L, Yang X, Jiao Y, Hao G, Liu Y
Food chemistry 2024 Jul 15;446:138807
Food chemistry 2024 Jul 15;446:138807
Protective effects of L-theanine and dihydromyricetin on reproductive function in male mice under heat stress.
Yang D, Xu K, Wang W, Chen P, Liu C, Liu S, Xu W, Xiao W
Food & function 2024 Jul 1;15(13):7093-7107
Food & function 2024 Jul 1;15(13):7093-7107
FOXA2 activates HIF2α expression to promote tumor progression and is regulated by the E3 ubiquitin ligase VHL in renal cell carcinoma.
Yang D, Li Q, Lu P, Wu D, Li W, Meng X, Xing M, Shangguan W, Chen B, Yang J, Zhang Z, Wang Z, Huang DCS, Zhao Q
The Journal of biological chemistry 2024 Jan;300(1):105535
The Journal of biological chemistry 2024 Jan;300(1):105535
Ambra1 in exosomes secreted by HK-2 cells damaged by supersaturated oxalate induce mitophagy and autophagy-ferroptosis in normal HK-2 cells to participate in the occurrence of kidney stones.
Su X, Song C, He Z, Song Q, Meng L, Dong C, Zhou J, Ke H, Xiong Y, Liu J, Liao W, Yang S
Biochimica et biophysica acta. Molecular cell research 2024 Jan;1871(1):119604
Biochimica et biophysica acta. Molecular cell research 2024 Jan;1871(1):119604
Huc-MSC-derived exosomal miR-144 alleviates inflammation in LPS-induced preeclampsia-like pregnant rats via the FosB/Flt-1 pathway.
Sun J, Zhang W
Heliyon 2024 Jan 30;10(2):e24575
Heliyon 2024 Jan 30;10(2):e24575
Deep learning enables the discovery of a novel cuproptosis-inducing molecule for the inhibition of hepatocellular carcinoma.
Yang F, Jia L, Zhou HC, Huang JN, Hou MY, Liu FT, Prabhu N, Li ZJ, Yang CB, Zou C, Nordlund P, Wang JG, Dai LY
Acta pharmacologica Sinica 2024 Feb;45(2):391-404
Acta pharmacologica Sinica 2024 Feb;45(2):391-404
Differential Proteomic Profiles of Coronary Serum Exosomes in Acute Myocardial Infarction Patients with or Without Diabetes Mellitus: ANGPTL6 Accelerates Regeneration of Endothelial Cells Treated with Rapamycin via MAPK Pathways.
Wang W, Zhao Y, Zhu P, Jia X, Wang C, Zhang Q, Li H, Wang J, Hou Y
Cardiovascular drugs and therapy 2024 Feb;38(1):13-29
Cardiovascular drugs and therapy 2024 Feb;38(1):13-29
Disrupted HSF1 regulation in normal and exceptional brain aging.
Trivedi R, Knopf B, Rakoczy S, Manocha GD, Brown-Borg H, Jurivich DA
Biogerontology 2024 Feb;25(1):147-160
Biogerontology 2024 Feb;25(1):147-160
The augmentation of cytotoxic immune cell functionality through physical exertion bolsters the potency of chemotherapy in models of mammary carcinoma.
Qin B, He Z, Xie L, Feng S, Ye J, Gui J, Sun X, Sang M
Cancer medicine 2024 Feb;13(3):e6951
Cancer medicine 2024 Feb;13(3):e6951
CircMTA2 Drives Gastric Cancer Progression through Suppressing MTA2 Degradation via Interacting with UCHL3.
Xie G, Lei B, Yin Z, Xu F, Liu X
International journal of molecular sciences 2024 Feb 29;25(5)
International journal of molecular sciences 2024 Feb 29;25(5)
Recruitment of BAG2 to DNAJ-PKAc scaffolds promotes cell survival and resistance to drug-induced apoptosis in fibrolamellar carcinoma.
Lauer SM, Omar MH, Golkowski MG, Kenerson HL, Lee KS, Pascual BC, Lim HC, Forbush K, Smith FD, Gordan JD, Ong SE, Yeung RS, Scott JD
Cell reports 2024 Feb 27;43(2):113678
Cell reports 2024 Feb 27;43(2):113678
Protein phosphatase 1 regulatory subunit 15 A promotes translation initiation and induces G2M phase arrest during cuproptosis in cancers.
Liu C, Chen L, Cong Y, Cheng L, Shuai Y, Lv F, Chen K, Song Y, Xing Y
Cell death & disease 2024 Feb 16;15(2):149
Cell death & disease 2024 Feb 16;15(2):149
Herpes simplex virus type 1 modifies the protein composition of extracellular vesicles to promote neurite outgrowth and neuroinfection.
Sun G, Kropp KA, Kirchner M, Plückebaum N, Selich A, Serrero M, Dhingra A, Cabrera JR, Ritter B, Bauerfeind R, Wyler E, Landthaler M, Schambach A, Sodeik B, Mertins P, Viejo-Borbolla A
mBio 2024 Feb 14;15(2):e0330823
mBio 2024 Feb 14;15(2):e0330823
Sirtuin 7 ameliorates cuproptosis, myocardial remodeling and heart dysfunction in hypertension through the modulation of YAP/ATP7A signaling.
Chen YF, Qi RQ, Song JW, Wang SY, Dong ZJ, Chen YH, Liu Y, Zhou XY, Li J, Liu XY, Zhong JC
Apoptosis : an international journal on programmed cell death 2024 Dec;29(11-12):2161-2182
Apoptosis : an international journal on programmed cell death 2024 Dec;29(11-12):2161-2182
Skin as outermost immune organ of vertebrates that elicits robust early immune responses after immunization with glycoprotein of spring viraemia of carp virus.
Zhao Z, Zhao L, Wei XF, Jia YJ, Zhu B
PLoS pathogens 2024 Dec;20(12):e1012744
PLoS pathogens 2024 Dec;20(12):e1012744
Immunomodulatory effect of mesenchymal stem cells-derived extracellular vesicles to modulate the regulatory T cells and Th1/Th2 imbalance in peripheral blood mononuclear cells of patients with allergic rhinitis.
Wang Z, Shahzad KA, Li X, Cai B, Xu M, Li J, Tan F
Scandinavian journal of immunology 2024 Dec;100(6):e13416
Scandinavian journal of immunology 2024 Dec;100(6):e13416
Exosome-delivered NR2F1-AS1 and NR2F1 drive phenotypic transition from dormancy to proliferation in treatment-resistant prostate cancer via stabilizing hormonal receptors.
Chen W, Mao Y, Zhan Y, Li W, Wu J, Mao X, Xu B, Shu F
Journal of nanobiotechnology 2024 Dec 18;22(1):761
Journal of nanobiotechnology 2024 Dec 18;22(1):761
Butyrolactone-I from Marine Fungal Metabolites Mitigates Heat-Stress-Induced Apoptosis in IPEC-J2 Cells and Mice Through the ROS/PERK/CHOP Signaling Pathway.
Niu X, Chen S, Wang X, Wen J, Liu X, Yong Y, Yu Z, Ma X, Abd El-Aty AM, Ju X
Marine drugs 2024 Dec 17;22(12)
Marine drugs 2024 Dec 17;22(12)
Bongkrekic acid alleviates airway inflammation via breaking the mPTP/mtDAMPs/RAGE feedback loop in a steroid-insensitive asthma model.
Chen Y, Huang J, Li Y, Chen Y, Gong Z, Xu M, Ma Y, Hu D, Peng X, Xu G, Cai S, Liu L, Zhao W, Zhao H
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2024 Aug;177:117111
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2024 Aug;177:117111
N-acetylcysteine stimulates the proliferation and differentiation in heat-stressed skeletal muscle cells.
Lu J, Zhao P, Ding X, Li H
Journal of thermal biology 2024 Aug;124:103958
Journal of thermal biology 2024 Aug;124:103958
Exosomal miR-106a-5p derived from intermittently hypoxic non-small-cell lung cancer increases tumor malignancy.
Ren J, Jin Z, Huang Y
Physiological reports 2024 Aug;12(15):e16157
Physiological reports 2024 Aug;12(15):e16157
Eupalinolide B suppresses pancreatic cancer by ROS generation and potential cuproptosis.
Huang Q, Yang J, Zhang J, Yao L, Jiang B, Du S, Li F, Peng Q, Qin L, Wang Y, Qi L
iScience 2024 Aug 16;27(8):110496
iScience 2024 Aug 16;27(8):110496
Data on mitochondrial respiratory function in skeletal muscle of adult male mice in response to 3-weeks heat stress.
Koma R, Matsumoto T, Yamazaki A, Shibaguchi T, Jue T, Masuda K
Data in brief 2024 Apr;53:110091
Data in brief 2024 Apr;53:110091
Dietary purple potato supplement attenuates DSS-induced colitis in mice: impact on mitochondrial function.
Sun Q, Bibi S, Xue Y, Du M, Chew B, Zhu MJ
The Journal of nutritional biochemistry 2024 Apr;126:109585
The Journal of nutritional biochemistry 2024 Apr;126:109585
Dual RNA sequencing of Helicobacter pylori and host cell transcriptomes reveals ontologically distinct host-pathogen interaction.
Hu W, Zhai ZY, Huang ZY, Chen ZM, Zhou P, Li XX, Yang GH, Bao CJ, You LJ, Cui XB, Xia GL, Ou Yang MP, Zhang L, Wu WKK, Li LF, Zhang YX, Xiao ZG, Gong W
mSystems 2024 Apr 16;9(4):e0020624
mSystems 2024 Apr 16;9(4):e0020624
Quantitative Measurement of Transthyretin Mistargeting by Proximity Labeling and Parallel Reaction Monitoring.
Lyu Z, Genereux JC
Frontiers in chemical biology 2023;2
Frontiers in chemical biology 2023;2
DNAJC8: a prognostic marker and potential therapeutic target for hepatocellular carcinoma.
Zhang Z, Ju M, Tang Z, He Z, Hua S
Frontiers in immunology 2023;14:1289548
Frontiers in immunology 2023;14:1289548
Cuproptosis enhances docetaxel chemosensitivity by inhibiting autophagy via the DLAT/mTOR pathway in prostate cancer.
Wen H, Qu C, Wang Z, Gao H, Liu W, Wang H, Sun H, Gu J, Yang Z, Wang X
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2023 Sep;37(9):e23145
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2023 Sep;37(9):e23145
Exploiting immunostimulatory mechanisms of immunogenic cell death to develop membrane-encapsulated nanoparticles as a potent tumor vaccine.
Liu Q, Hu Y, Zheng P, Yang Y, Fu Y, Yang Y, Duan B, Wang M, Li D, Li W, He J, Zheng X, Long Q, Ma Y
Journal of nanobiotechnology 2023 Sep 8;21(1):326
Journal of nanobiotechnology 2023 Sep 8;21(1):326
Fluorescence Tracking of Small Extracellular Vesicles In Vivo.
Chen Y, Shi Y, Tao Z
Pharmaceutics 2023 Sep 8;15(9)
Pharmaceutics 2023 Sep 8;15(9)
Quantitative proteomic analysis of local and systemic extracellular vesicles during Eimeria falciformis infectious cycle in the host.
Olajide JS, Qu Z, Yang S, Yang B, Xu X, Wang J, Cai J
Parasites & vectors 2023 Sep 27;16(1):339
Parasites & vectors 2023 Sep 27;16(1):339
USP14 Positively Modulates Head and Neck Squamous Carcinoma Tumorigenesis and Potentiates Heat Shock Pathway through HSF1 Stabilization.
Wang J, Xiang Y, Xie Z, Fan M, Fang S, Wan H, Zhao R, Zeng F, Hua Q
Cancers 2023 Sep 1;15(17)
Cancers 2023 Sep 1;15(17)
Evaluation the role of cuproptosis-related genes in the pathogenesis, diagnosis and molecular subtypes identification of atherosclerosis.
Wang M, Cheng L, Xiang Q, Gao Z, Ding Y, Xie H, Chen X, Yu P, Shen L
Heliyon 2023 Oct;9(10):e21158
Heliyon 2023 Oct;9(10):e21158
Changes in the components of salivary exosomes due to initial periodontal therapy.
Yamaguchi A, Tsuruya Y, Igarashi K, Jin Z, Yamazaki-Takai M, Takai H, Nakayama Y, Ogata Y
Journal of periodontal & implant science 2023 Oct;53(5):347-361
Journal of periodontal & implant science 2023 Oct;53(5):347-361
Targeting TNFAIP2 induces immunogenic cell death and sensitizes glioblastoma multiforme to anti-PD-1 therapy.
Hou C, Shi S, Gao M, Ji J, Ma C, Wang T, Chen T, Liu Y, Zhong J, Zheng Y, Ye J, Ke Y
Journal of neuro-oncology 2023 Oct;165(1):79-90
Journal of neuro-oncology 2023 Oct;165(1):79-90
Phenyl dialkynylcarbinols, a Bioinspired Series of Synthetic Antitumor Acetylenic Lipids.
Bossuat M, Rullière P, Preuilh N, Peixoto A, Joly E, Gomez JG, Bourkhis M, Rodriguez F, Gonçalves F, Fabing I, Gaspard H, Bernardes-Génisson V, Maraval V, Ballereau S, Chauvin R, Britton S, Génisson Y
Journal of medicinal chemistry 2023 Oct 26;66(20):13918-13945
Journal of medicinal chemistry 2023 Oct 26;66(20):13918-13945
Tumor-repopulating cell-derived microparticles elicit cascade amplification of chemotherapy-induced antitumor immunity to boost anti-PD-1 therapy.
Bie N, Yong T, Wei Z, Liang Q, Zhang X, Li S, Li X, Li J, Gan L, Yang X
Signal transduction and targeted therapy 2023 Oct 25;8(1):408
Signal transduction and targeted therapy 2023 Oct 25;8(1):408
Effective myocardial infarction treatment by targeted accumulation of Sulforaphane using porous magnetic silica nanoparticles.
Zhang J, Dong Y, Liu X, Jin H, Wang S, An N, Wang L
International journal of pharmaceutics 2023 Oct 15;645:123389
International journal of pharmaceutics 2023 Oct 15;645:123389
M2 macrophage exosomal LINC01001 promotes non-small cell lung cancer development by affecting METTL3 and glycolysis pathway.
Xu L, Li K, Li J, Xu F, Liang S, Kong Y, Chen B
Cancer gene therapy 2023 Nov;30(11):1569-1580
Cancer gene therapy 2023 Nov;30(11):1569-1580
Nuclear import carrier Hikeshi cooperates with HSP70 to promote murine oligodendrocyte differentiation and CNS myelination.
Li L, Li D, Sun D, Zhang X, Lei W, Wu M, Huang Q, Nian X, Dai W, Lu X, Zhou Z, Zhu Y, Xiao Y, Zhang L, Mo W, Liu Z, Zhang L
Developmental cell 2023 Nov 6;58(21):2275-2291.e6
Developmental cell 2023 Nov 6;58(21):2275-2291.e6
The proteomics analysis of extracellular vesicles revealed the possible function of heat shock protein 60 in Helicobacter pylori infection.
Li Y, Cao H, Qiu D, Wang N, Wang Y, Wen T, Wang J, Zhu H
Cancer cell international 2023 Nov 16;23(1):272
Cancer cell international 2023 Nov 16;23(1):272
The HDAC inhibitor HFY-4A improves TUSC2 transcription to induce immunogenic cell death in breast cancer.
Yin Y, Guan X, Li G, Chen C, Duan Y, Yu Z
Toxicology and applied pharmacology 2023 Nov 1;478:116698
Toxicology and applied pharmacology 2023 Nov 1;478:116698
Pre-Induced ICD Membrane-Coated Carrier-Free Nanoparticles for the Personalized Lung Cancer Immunotherapy.
Li S, Jiang S, Rahman MSU, Mei J, Wang X, Jiang J, Chen Y, Xu S, Liu Y
Small methods 2023 May;7(5):e2201569
Small methods 2023 May;7(5):e2201569
SIRT2 regulates extracellular vesicle-mediated liver-bone communication.
Lin L, Guo Z, He E, Long X, Wang D, Zhang Y, Guo W, Wei Q, He W, Wu W, Li J, Wo L, Hong D, Zheng J, He M, Zhao Q
Nature metabolism 2023 May;5(5):821-841
Nature metabolism 2023 May;5(5):821-841
miR-27a-3p relieves heat stress-induced mitochondrial damage and aberrant milk protein synthesis through MEK/ERK pathway in BMECs.
Wang Y, Wu J, Xia SW, Zhao F, Ding Q, Ye XM, Zhong JF, Chen KL, Wang HL
Cell stress & chaperones 2023 May;28(3):265-274
Cell stress & chaperones 2023 May;28(3):265-274
Bone mesenchymal stem cell-derived exosomes involved co-delivery and synergism effect with icariin via mussel-inspired multifunctional hydrogel for cartilage protection.
Zeng J, Sun P, Zhao Y, Fang X, Wu Z, Qi X
Asian journal of pharmaceutical sciences 2023 May;18(3):100799
Asian journal of pharmaceutical sciences 2023 May;18(3):100799
Viral subversion of selective autophagy is critical for biogenesis of virus replication organelles.
Lan Y, van Leur SW, Fernando JA, Wong HH, Kampmann M, Siu L, Zhang J, Li M, Nicholls JM, Sanyal S
Nature communications 2023 May 10;14(1):2698
Nature communications 2023 May 10;14(1):2698
Exosomes from tubular epithelial cells undergoing epithelial-to-mesenchymal transition promote renal fibrosis by M1 macrophage activation.
Lu Y, Zhang R, Gu X, Wang X, Xi P, Chen X
FASEB bioAdvances 2023 Mar;5(3):101-113
FASEB bioAdvances 2023 Mar;5(3):101-113
HSPA1A ameliorated spinal cord injury in rats by inhibiting apoptosis to exert neuroprotective effects.
He X, Guo X, Deng B, Kang J, Liu W, Zhang G, Wang Y, Yang Y, Kang X
Experimental neurology 2023 Mar;361:114301
Experimental neurology 2023 Mar;361:114301
Taxol‑resistant breast cancer cell‑derived exosome‑delivered miR‑187‑5p regulates the growth of breast cancer cells via ABCD2 and Wnt/β‑catenin signaling.
Wu T, Zhu D, Wu X, Zhang N, Zhang Q
Oncology letters 2023 Mar;25(3):119
Oncology letters 2023 Mar;25(3):119
PTEN Deficiency Facilitates Exosome Secretion and Metastasis in Cholangiocarcinoma by Impairing TFEB-mediated Lysosome Biogenesis.
Jiang TY, Shi YY, Cui XW, Pan YF, Lin YK, Feng XF, Ding ZW, Yang C, Tan YX, Dong LW, Wang HY
Gastroenterology 2023 Mar;164(3):424-438
Gastroenterology 2023 Mar;164(3):424-438
A curcumin analogue GO-Y030 depletes cancer stem cells by inhibiting the interaction between the HSP70/HSP40 complex and its substrates.
Suzuki M, Yamamoto Y, Nishijima-Matsunobu A, Kawasaki Y, Shibata H, Omori Y
FEBS open bio 2023 Mar;13(3):434-446
FEBS open bio 2023 Mar;13(3):434-446
Cytokine profiles of plasma extracellular vesicles as progression biomarkers in Parkinson's disease.
Chan L, Chung CC, Yu RC, Hong CT
Aging 2023 Mar 9;15(5):1603-1614
Aging 2023 Mar 9;15(5):1603-1614
Extracellular vesicles from Zika virus-infected cells display viral E protein that binds ZIKV-neutralizing antibodies to prevent infection enhancement.
Zhao F, Xu Y, Liu N, Lv D, Chen Y, Liu Z, Jin X, Xiao M, Lavillette D, Zhong J, Bartenschlager R, Long G
The EMBO journal 2023 Mar 15;42(6):e112096
The EMBO journal 2023 Mar 15;42(6):e112096
Near-Infrared Phototheranostic Iron Pyrite Nanocrystals Simultaneously Induce Dual Cell Death Pathways via Enhanced Fenton Reactions in Triple-Negative Breast Cancer.
Zhao C, Liu Z, Chang CC, Chen YC, Zhang Q, Zhang XD, Andreou C, Pang J, Liu ZX, Wang DY, Kircher MF, Yang J
ACS nano 2023 Mar 14;17(5):4261-4278
ACS nano 2023 Mar 14;17(5):4261-4278
A cytosolic surveillance mechanism activates the mitochondrial UPR.
Sutandy FXR, Gößner I, Tascher G, Münch C
Nature 2023 Jun;618(7966):849-854
Nature 2023 Jun;618(7966):849-854
Engineered allostery in light-regulated LOV-Turbo enables precise spatiotemporal control of proximity labeling in living cells.
Lee SY, Cheah JS, Zhao B, Xu C, Roh H, Kim CK, Cho KF, Udeshi ND, Carr SA, Ting AY
Nature methods 2023 Jun;20(6):908-917
Nature methods 2023 Jun;20(6):908-917
Recruitment of BAG2 to DNAJ-PKAc scaffolds promotes cell survival and resistance to drug-induced apoptosis in fibrolamellar carcinoma.
Lauer SM, Omar MH, Golkowski MG, Kenerson HL, Pascual BC, Forbush K, Smith FD, Gordan J, Ong SE, Yeung RS, Scott JD
bioRxiv : the preprint server for biology 2023 Jun 28;
bioRxiv : the preprint server for biology 2023 Jun 28;
Albumosomes formed by cytoplasmic pre-folding albumin maintain mitochondrial homeostasis and inhibit nonalcoholic fatty liver disease.
Ma B, Ju A, Zhang S, An Q, Xu S, Liu J, Yu L, Fu Y, Luo Y
Signal transduction and targeted therapy 2023 Jun 16;8(1):229
Signal transduction and targeted therapy 2023 Jun 16;8(1):229
Dextran 40 hybrid biomimetic bismuth-nanoflower designed for NIR II-triggered hypoxic tumor thermoradiotherapy via macrophage escape.
Wen J, Liu C, Liu J, Wang L, Miao S, Chen D, Wang Q, Huo M, Shen Y
Carbohydrate polymers 2023 Jun 15;310:120697
Carbohydrate polymers 2023 Jun 15;310:120697
Carnosinase-1 Knock-Out Reduces Kidney Fibrosis in Type-1 Diabetic Mice on High Fat Diet.
Pfeffer T, Wetzel C, Kirschner P, Bartosova M, Poth T, Schwab C, Poschet G, Zemva J, Bulkescher R, Damgov I, Thiel C, Garbade SF, Klingbeil K, Peters V, Schmitt CP
Antioxidants (Basel, Switzerland) 2023 Jun 14;12(6)
Antioxidants (Basel, Switzerland) 2023 Jun 14;12(6)
Long noncoding RNA HITT coordinates with RGS2 to inhibit PD-L1 translation in T cell immunity.
Lin Q, Liu T, Wang X, Hou G, Xiang Z, Zhang W, Zheng S, Zhao D, Leng Q, Zhang X, Lu M, Guan T, Liu H, Hu Y
The Journal of clinical investigation 2023 Jun 1;133(11)
The Journal of clinical investigation 2023 Jun 1;133(11)
Control of SOX2 protein stability and tumorigenic activity by E3 ligase CHIP in esophageal cancer cells.
Kang L, Zhang H, Wang Y, Chu M, He J, Xue M, Pan L, Zhang Y, Wang Z, Chen Z, Huang Y, Chen Z, Li E, Li J, Xu L, Zhang R, Wong J
Oncogene 2023 Jul;42(30):2315-2328
Oncogene 2023 Jul;42(30):2315-2328
Combination therapy with BMSCs‑exosomes and porous tantalum for the repair of femur supracondylar defects.
Yang F, Wu M, Chen H, Ma S, Liu J, Li C, Li Y, Yang J, Liu B, Zhao D
Molecular medicine reports 2023 Jul;28(1)
Molecular medicine reports 2023 Jul;28(1)
Roles of hypoxic environment and M2 macrophage-derived extracellular vesicles on the progression of non-small cell lung cancer.
Chu X, Wang Z, Wang W, Liu W, Cao Y, Feng L
BMC pulmonary medicine 2023 Jul 3;23(1):239
BMC pulmonary medicine 2023 Jul 3;23(1):239
Cellular Exposure to Chloroacetanilide Herbicides Induces Distinct Protein Destabilization Profiles.
Quanrud GM, Lyu Z, Balamurugan SV, Canizal C, Wu HT, Genereux JC
ACS chemical biology 2023 Jul 21;18(7):1661-1676
ACS chemical biology 2023 Jul 21;18(7):1661-1676
Quantitative Measurement of Secretory Protein Mistargeting by Proximity Labeling and Parallel Reaction Monitoring.
Lyu Z, Genereux JC
bioRxiv : the preprint server for biology 2023 Jul 20;
bioRxiv : the preprint server for biology 2023 Jul 20;
Lysine butyrylation of HSP90 regulated by KAT8 and HDAC11 confers chemoresistance.
He Y, Zheng CC, Yang J, Li SJ, Xu TY, Wei X, Chen WY, Jiang ZL, Xu JJ, Zhang GG, Cheng C, Chen KS, Shi XY, Qin DJ, Liu JB, Li B
Cell discovery 2023 Jul 18;9(1):74
Cell discovery 2023 Jul 18;9(1):74
Cardiac myofibrillogenesis is spatiotemporally modulated by the molecular chaperone UNC45B.
Lu SH, Wu YH, Su LY, Hsu ZT, Weng TH, Wang HY, Yu C, Hsu PW, Tsai SY
Stem cell reports 2023 Jul 11;18(7):1405-1420
Stem cell reports 2023 Jul 11;18(7):1405-1420
Extracellular vesicles from mesenchymal stem cells reduce neuroinflammation in hippocampus and restore cognitive function in hyperammonemic rats.
Izquierdo-Altarejos P, Cabrera-Pastor A, Martínez-García M, Sánchez-Huertas C, Hernández A, Moreno-Manzano V, Felipo V
Journal of neuroinflammation 2023 Jan 2;20(1):1
Journal of neuroinflammation 2023 Jan 2;20(1):1
Exosomal microRNAs regulate the heat stress response in sea cucumber Apostichopus japonicus.
Huo D, Su F, Yang H, Sun L
Ecotoxicology and environmental safety 2023 Jan 1;249:114419
Ecotoxicology and environmental safety 2023 Jan 1;249:114419
iASPP suppression mediates terminal UPR and improves BRAF-inhibitor sensitivity of colon cancers.
Zheng S, Wang X, Liu H, Zhao D, Lin Q, Jiang Q, Li L, Hu Y
Cell death and differentiation 2023 Feb;30(2):327-340
Cell death and differentiation 2023 Feb;30(2):327-340
Hypoxia aggravates the burden of yellowstripe goby (Mugilogobius chulae) under atorvastatin exposure.
Wang Y, Tang T, Ren J, Zhao Y, Hou Y, Nie X
Aquatic toxicology (Amsterdam, Netherlands) 2023 Feb;255:106381
Aquatic toxicology (Amsterdam, Netherlands) 2023 Feb;255:106381
lncRNA SND1-IT1 delivered via intracerebral hemorrhage-derived exosomes affect the growth of human microglia by regulating the miR-124-3p/MTF1 axis.
Wang J, Teng F, Liu S, Pan X, Yang B, Wu W
Journal of cellular physiology 2023 Feb;238(2):366-378
Journal of cellular physiology 2023 Feb;238(2):366-378
Exosomes Derived from AT2R-Overexpressing BMSC Prevent Restenosis After Carotid Artery Injury by Attenuating the Injury-Induced Neointimal Hyperplasia.
Zou X, Liao Y, Liu Z, Xu X, Sun W, Qin H, Wang H, Liu J, Jing T
Journal of cardiovascular translational research 2023 Feb;16(1):112-126
Journal of cardiovascular translational research 2023 Feb;16(1):112-126
Distinctive chaperonopathy in skeletal muscle associated with the dominant variant in DNAJB4.
Inoue M, Noguchi S, Inoue YU, Iida A, Ogawa M, Bengoechea R, Pittman SK, Hayashi S, Watanabe K, Hosoi Y, Sano T, Takao M, Oya Y, Takahashi Y, Miyajima H, Weihl CC, Inoue T, Nishino I
Acta neuropathologica 2023 Feb;145(2):235-255
Acta neuropathologica 2023 Feb;145(2):235-255
Sex-Inclined Piwi-Interacting RNAs in Serum Exosomes for Sex Determination in the Greater Amberjack (Seriola dumerili).
Deng Q, Zhao N, Ru X, Hao R, Zhang B, Zhu C
International journal of molecular sciences 2023 Feb 8;24(4)
International journal of molecular sciences 2023 Feb 8;24(4)
Negatively charged bladder acellular matrix loaded with positively charged adipose-derived mesenchymal stem cell-derived small extracellular vesicles for bladder tissue engineering.
Yang T, Zhao F, Zhao J, Geng J, Shao C, Liu J, Sheng F, Zhou L, Xu H, Jia R
Journal of controlled release : official journal of the Controlled Release Society 2023 Dec;364:718-733
Journal of controlled release : official journal of the Controlled Release Society 2023 Dec;364:718-733
Tryptophan alleviates intestinal damage through regulating necroptosis and TLR4/NOD signaling pathways in pigs after lipopolysaccharide challenge.
Tao J, Liu G, Gu K, Jia G, Zhao H, Chen X, Tian G, Cai J, Wang J
Animal biotechnology 2023 Dec;34(9):4938-4946
Animal biotechnology 2023 Dec;34(9):4938-4946
Tryptophan alleviates lipopolysaccharide-induced liver injury and inflammation by modulating necroptosis and pyroptosis signaling pathways in piglets.
Gu K, Wang F, Sun W, Liu G, Jia G, Zhao H, Chen X, Wu C, Tian G, Cai J, Zhang R, Wang J
Animal biotechnology 2023 Dec;34(8):4069-4080
Animal biotechnology 2023 Dec;34(8):4069-4080
MiR-223-3p overexpressed adipose mesenchymal stem cell-derived exosomes promote wound healing via targeting MAPK10.
Liu X, Jin S, Liu J, Xu X
Acta histochemica 2023 Dec;125(8):152102
Acta histochemica 2023 Dec;125(8):152102
Caspase-9 inhibition triggers Hsp90-based chemotherapy-mediated tumor intrinsic innate sensing and enhances antitumor immunity.
Li J, Han X, Sun M, Li W, Yang G, Chen H, Guo B, Li J, Li X, Wang H
Journal for immunotherapy of cancer 2023 Dec 6;11(12)
Journal for immunotherapy of cancer 2023 Dec 6;11(12)
Betaine ameliorates heat stress-induced apoptosis by affecting oxidative and endoplasmic reticulum stress in mouse Leydig cells.
Xiong Y, Li B, Wang K, Li J, He S
Bioscience, biotechnology, and biochemistry 2023 Dec 19;88(1):53-62
Bioscience, biotechnology, and biochemistry 2023 Dec 19;88(1):53-62
Dysregulated Autophagy and Sarcomere Dysfunction in Patients With Heart Failure With Co-Occurrence of P63A and P380S BAG3 Variants.
Martin TG, Pak H, Gerhard GS, Merali S, Merali C, Lemster B, Dubey P, McTiernan CF, Bristow MR, Feldman AM, Kirk JA
Journal of the American Heart Association 2023 Dec 19;12(24):e029938
Journal of the American Heart Association 2023 Dec 19;12(24):e029938
Integrated bioinformatics and experiment revealed that cuproptosis is the potential common pathogenesis of three kinds of primary cardiomyopathy.
Wang M, Xu X, Li J, Gao Z, Ding Y, Chen X, Xiang Q, Shen L
Aging 2023 Dec 11;15(23):14210-14241
Aging 2023 Dec 11;15(23):14210-14241
Mechanism of non-steroidal anti-androgen-induced liver injury: Reactive metabolites of flutamide and bicalutamide activate inflammasomes.
Kato R, Yamada T, Noda T, Tanaka S, Kohda Y, Ijiri Y
Toxicology in vitro : an international journal published in association with BIBRA 2023 Aug;90:105606
Toxicology in vitro : an international journal published in association with BIBRA 2023 Aug;90:105606
Exosomal PGAM1 promotes prostate cancer angiogenesis and metastasis by interacting with ACTG1.
Luo JQ, Yang TW, Wu J, Lai HH, Zou LB, Chen WB, Zhou XM, Lv DJ, Cen SR, Long ZN, Mao YY, Zheng PX, Su XH, Xian ZY, Shu FP, Mao XM
Cell death & disease 2023 Aug 4;14(8):502
Cell death & disease 2023 Aug 4;14(8):502
Tumor-Associated Extracellular Microvesicles with Fluorine-Modified Carbohydrate Antigens Trigger a Stronger Antitumor Immune Response.
Mo J, Zou Y, Li BH, Li G, Zheng XJ, Liu Y, Ye XS
ACS applied materials & interfaces 2023 Aug 30;15(34):40201-40212
ACS applied materials & interfaces 2023 Aug 30;15(34):40201-40212
Effects of diazoxide on streptozotocin induced β cell damage via HSP70/HSP90/TLR4/AMPK signaling pathways.
Kaya ST
Biotechnic & histochemistry : official publication of the Biological Stain Commission 2023 Apr;98(3):210-219
Biotechnic & histochemistry : official publication of the Biological Stain Commission 2023 Apr;98(3):210-219
Degradation of neurodegenerative disease-associated TDP-43 aggregates and oligomers via a proteolysis-targeting chimera.
Tseng YL, Lu PC, Lee CC, He RY, Huang YA, Tseng YC, Cheng TR, Huang JJ, Fang JM
Journal of biomedical science 2023 Apr 26;30(1):27
Journal of biomedical science 2023 Apr 26;30(1):27
Differentially Expressed microRNAs in Peritoneal Dialysis Effluent-Derived Exosomes from the Patients with Ultrafiltration Failure.
Wu W, Wu X, Cheng Z, Yang Z, Lu M, Cheng J
Genetics research 2022;2022:2276175
Genetics research 2022;2022:2276175
Antimicrobial Effect of Extracellular Vesicles Derived From Human Oral Mucosal Epithelial Cells on Candida albicans.
Zhao M, Zhang M, Xu K, Wu K, Xie R, Li R, Wang Q, Liu W, Wang W, Wang X
Frontiers in immunology 2022;13:777613
Frontiers in immunology 2022;13:777613
Exosome-transmitted miR-3124-5p promotes cholangiocarcinoma development via targeting GDF11.
Gao H, He Z, Gao C, Liu N, Zhang Z, Niu W, Niu J, Peng C
Frontiers in oncology 2022;12:936507
Frontiers in oncology 2022;12:936507
PINK1-Dependent Mitophagy Reduced Endothelial Hyperpermeability and Cell Migration Capacity Under Simulated Microgravity.
Li C, Pan Y, Tan Y, Wang Y, Sun X
Frontiers in cell and developmental biology 2022;10:896014
Frontiers in cell and developmental biology 2022;10:896014
HucMSC-Ex carrying miR-203a-3p.2 ameliorates colitis through the suppression of caspase11/4-induced macrophage pyroptosis.
Xu Y, Tang X, Fang A, Yan J, Kofi Wiredu Ocansey D, Zhang X, Mao F
International immunopharmacology 2022 Sep;110:108925
International immunopharmacology 2022 Sep;110:108925
Depletion of serum-derived exosomes aggravates heat stress-induced damage of bovine mammary epithelial cells.
Wang Y, Wang HL, Lin ZP, Zhong JF, Chen KL, Duan X
Molecular biology reports 2022 Oct;49(10):9297-9305
Molecular biology reports 2022 Oct;49(10):9297-9305
c-Myc Sustains Pancreatic Cancer Cell Survival and mutp53 Stability through the Mevalonate Pathway.
Romeo MA, Gilardini Montani MS, Arena A, Benedetti R, D'Orazi G, Cirone M
Biomedicines 2022 Oct 5;10(10)
Biomedicines 2022 Oct 5;10(10)
Integrated Analysis of Transcriptome and microRNA Profile Reveals the Toxicity of Euphorbia Factors toward Human Colon Adenocarcinoma Cell Line Caco-2.
Zou L, Bao W, Gao Y, Chen M, Wu Y, Wang S, Li C, Zhang J, Zhang D, Wang Q, Zhu A
Molecules (Basel, Switzerland) 2022 Oct 16;27(20)
Molecules (Basel, Switzerland) 2022 Oct 16;27(20)
Defective Human SRP Induces Protein Quality Control and Triggers Stress Response.
Tikhonova EB, Gutierrez Guarnizo SA, Kellogg MK, Karamyshev A, Dozmorov IM, Karamysheva ZN, Karamyshev AL
Journal of molecular biology 2022 Nov 30;434(22):167832
Journal of molecular biology 2022 Nov 30;434(22):167832
Activation of the Chemokine Receptor CCR1 and Preferential Recruitment of Gαi Suppress RSV Replication: Implications for Developing Novel Respiratory Syncytial Virus Treatment Strategies.
Li J, Xue L, Wang J, Meng A, Qiao J, Li M, Wang X, Meng L, Ning J, Gao X, Li W, Ma C, Wei L
Journal of virology 2022 Nov 23;96(22):e0130922
Journal of virology 2022 Nov 23;96(22):e0130922
Design, synthesis, and biological evaluation of novel dual inhibitors of heat shock protein 90/mammalian target of rapamycin (Hsp90/mTOR) against bladder cancer cells.
Pan Z, Chen Y, Pang H, Wang X, Zhang Y, Xie X, He G
European journal of medicinal chemistry 2022 Nov 15;242:114674
European journal of medicinal chemistry 2022 Nov 15;242:114674
Exosome-derived FGD5-AS1 promotes tumor-associated macrophage M2 polarization-mediated pancreatic cancer cell proliferation and metastasis.
He Z, Wang J, Zhu C, Xu J, Chen P, Jiang X, Chen Y, Jiang J, Sun C
Cancer letters 2022 Nov 1;548:215751
Cancer letters 2022 Nov 1;548:215751
SIRT4 Expression Ameliorates the Detrimental Effect of Heat Stress via AMPK/mTOR Signaling Pathway in BMECs.
Ding Q, Wang Y, Xia SW, Zhao F, Zhong JF, Wang HL, Chen KL
International journal of molecular sciences 2022 Nov 1;23(21)
International journal of molecular sciences 2022 Nov 1;23(21)
BAG3 protects chondrocytes against lumbar facet joint osteoarthritis by regulating autophagy and apoptosis.
Lu X, Zhang J, Xue P, Wang Q, Wang X, Sun Y, Cui Z
Journal of physiology and biochemistry 2022 May;78(2):427-437
Journal of physiology and biochemistry 2022 May;78(2):427-437
Class 3 phosphoinositide 3-kinase promotes hepatic glucocorticoid receptor stability and transcriptional activity.
Shibayama Y, Alkhoury C, Nemazanyy I, F Henneman N, Cagnard N, Girard M, Atsumi T, Panasyuk G
Acta physiologica (Oxford, England) 2022 May;235(1):e13793
Acta physiologica (Oxford, England) 2022 May;235(1):e13793
Triptolide promotes degradation of the unfolded gain-of-function Tp53(R175H/Y220C) mutant protein by initiating heat shock protein 70 transcription in non-small cell lung cancer.
Zhou J, Luo J, Li P, Zhou Y, Li P, Wang F, Mallio CA, Rossi G, Jalal AH, Filipovic N, Tian Z, Zhao X
Translational lung cancer research 2022 May;11(5):802-816
Translational lung cancer research 2022 May;11(5):802-816
Inhibition of the CDK2 and Cyclin A complex leads to autophagic degradation of CDK2 in cancer cells.
Zhang J, Gan Y, Li H, Yin J, He X, Lin L, Xu S, Fang Z, Kim BW, Gao L, Ding L, Zhang E, Ma X, Li J, Li L, Xu Y, Horne D, Xu R, Yu H, Gu Y, Huang W
Nature communications 2022 May 20;13(1):2835
Nature communications 2022 May 20;13(1):2835
Engineered exosome as targeted lncRNA MEG3 delivery vehicles for osteosarcoma therapy.
Huang X, Wu W, Jing D, Yang L, Guo H, Wang L, Zhang W, Pu F, Shao Z
Journal of controlled release : official journal of the Controlled Release Society 2022 Mar;343:107-117
Journal of controlled release : official journal of the Controlled Release Society 2022 Mar;343:107-117
In situ injectable hydrogel-loaded drugs induce anti-tumor immune responses in melanoma immunochemotherapy.
Li J, Luo G, Zhang C, Long S, Guo L, Yang G, Wang F, Zhang L, Shi L, Fu Y, Zhang Y
Materials today. Bio 2022 Mar;14:100238
Materials today. Bio 2022 Mar;14:100238
LONP1-mediated mitochondrial quality control safeguards metabolic shifts in heart development.
Zhao K, Huang X, Zhao W, Lu B, Yang Z
Development (Cambridge, England) 2022 Mar 15;149(6)
Development (Cambridge, England) 2022 Mar 15;149(6)
SUMO2-mediated SUMOylation of SH3GLB1 promotes ionizing radiation-induced hypertrophic cardiomyopathy through mitophagy activation.
Gao A, Zou J, Mao Z, Zhou H, Zeng G
European journal of pharmacology 2022 Jun 5;924:174980
European journal of pharmacology 2022 Jun 5;924:174980
CircEZH2/miR-133b/IGF2BP2 aggravates colorectal cancer progression via enhancing the stability of m(6)A-modified CREB1 mRNA.
Yao B, Zhang Q, Yang Z, An F, Nie H, Wang H, Yang C, Sun J, Chen K, Zhou J, Bai B, Gu S, Zhao W, Zhan Q
Molecular cancer 2022 Jun 30;21(1):140
Molecular cancer 2022 Jun 30;21(1):140
Exosomal tRF-Leu-AAG-001 derived from mast cell as a potential non-invasive diagnostic biomarker for endometriosis.
Li Y, Cui S, Xu Z, Zhang Y, Wu T, Zhang J, Chen Y
BMC women's health 2022 Jun 25;22(1):253
BMC women's health 2022 Jun 25;22(1):253
Comparative transcriptome and Lipidome analyses suggest a lipid droplet-specific response to heat exposure of brown adipose tissue in normal and obese mice.
Wang Q, Liu Y, Xu Y, Jin Y, Wu J, Ren Z
Life sciences 2022 Jun 15;299:120540
Life sciences 2022 Jun 15;299:120540
Single-cell analysis of human basal cell carcinoma reveals novel regulators of tumor growth and the tumor microenvironment.
Guerrero-Juarez CF, Lee GH, Liu Y, Wang S, Karikomi M, Sha Y, Chow RY, Nguyen TTL, Iglesias VS, Aasi S, Drummond ML, Nie Q, Sarin K, Atwood SX
Science advances 2022 Jun 10;8(23):eabm7981
Science advances 2022 Jun 10;8(23):eabm7981
Targeted Analysis of HSP70 Isoforms in Human Spermatozoa in the Context of Capacitation and Motility.
Grassi S, Bisconti M, Martinet B, Arcolia V, Simon JF, Wattiez R, Leroy B, Hennebert E
International journal of molecular sciences 2022 Jun 10;23(12)
International journal of molecular sciences 2022 Jun 10;23(12)
Mesenchymal Stem Cell-Derived Exosomes Attenuate Epithelial-Mesenchymal Transition of HK-2 Cells.
Yin S, Zhou S, Ren D, Zhang J, Xin H, He X, Gao H, Hou J, Zeng F, Lu Y, Zhang X, Fan M
Tissue engineering. Part A 2022 Jul;28(13-14):651-659
Tissue engineering. Part A 2022 Jul;28(13-14):651-659
Eimeria falciformis secretes extracellular vesicles to modulate proinflammatory response during interaction with mouse intestinal epithelial cells.
Olajide JS, Xiong L, Yang S, Qu Z, Xu X, Yang B, Wang J, Liu B, Ma X, Cai J
Parasites & vectors 2022 Jul 8;15(1):245
Parasites & vectors 2022 Jul 8;15(1):245
miR-126-3p containing exosomes derived from human umbilical cord mesenchymal stem cells promote angiogenesis and attenuate ovarian granulosa cell apoptosis in a preclinical rat model of premature ovarian failure.
Qu Q, Liu L, Cui Y, Liu H, Yi J, Bing W, Liu C, Jiang D, Bi Y
Stem cell research & therapy 2022 Jul 26;13(1):352
Stem cell research & therapy 2022 Jul 26;13(1):352
Magnetic hyperthermia induces effective and genuine immunogenic tumor cell death with respect to exogenous heating.
Yan B, Liu C, Wang S, Li H, Jiao J, Lee WSV, Zhang S, Hou Y, Hou Y, Ma X, Fan H, Lv Y, Liu X
Journal of materials chemistry. B 2022 Jul 20;10(28):5364-5374
Journal of materials chemistry. B 2022 Jul 20;10(28):5364-5374
Monitoring Protein Import into the Endoplasmic Reticulum in Living Cells with Proximity Labeling.
Lyu Z, Sycks MM, Espinoza MF, Nguyen KK, Montoya MR, Galapate CM, Mei L, Genereux JC
ACS chemical biology 2022 Jul 15;17(7):1963-1977
ACS chemical biology 2022 Jul 15;17(7):1963-1977
BAG3 Regulation of RAB35 Mediates the Endosomal Sorting Complexes Required for Transport/Endolysosome Pathway and Tau Clearance.
Lin H, Tang M, Ji C, Girardi P, Cvetojevic G, Chen D, Koren SA, Johnson GVW
Biological psychiatry 2022 Jul 1;92(1):10-24
Biological psychiatry 2022 Jul 1;92(1):10-24
Fine-Tuning of Cholesterol Homeostasis Controls Erythroid Differentiation.
Lu Z, Huang L, Li Y, Xu Y, Zhang R, Zhou Q, Sun Q, Lu Y, Chen J, Shen Y, Li J, Zhao B
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2022 Jan;9(2):e2102669
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2022 Jan;9(2):e2102669
PKM2 compensates for proteasome dysfunction by mediating the formation of the CHIP-HSP70-BAG3 complex and the aggregation of ubiquitinated proteins.
Zhang C, Tang Q, Xia H, Xu H, Bi F
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2022 Jan;36(1):e22121
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2022 Jan;36(1):e22121
Pharmacological inhibition of BAG3-HSP70 with the proposed cancer therapeutic JG-98 is toxic for cardiomyocytes.
Martin TG, Delligatti CE, Muntu NA, Stachowski-Doll MJ, Kirk JA
Journal of cellular biochemistry 2022 Jan;123(1):128-141
Journal of cellular biochemistry 2022 Jan;123(1):128-141
Zinc Protects against Heat Stress-Induced Apoptosis via the Inhibition of Endoplasmic Reticulum Stress in TM3 Leydig Cells.
Xiong Y, Li J, He S
Biological trace element research 2022 Feb;200(2):728-739
Biological trace element research 2022 Feb;200(2):728-739
Exosomes released from Sertoli cells contribute to the survival of Leydig cells through CCL20 in rats.
Ma Y, Zhou Y, Zou SS, Sun Y, Chen XF
Molecular human reproduction 2022 Feb 4;28(2)
Molecular human reproduction 2022 Feb 4;28(2)
VPA and TSA Interrupt the Interplay between mutp53 and HSP70, Leading to CHK1 and RAD51 Down-Regulation and Sensitizing Pancreatic Cancer Cells to AZD2461 PARP Inhibitor.
Romeo MA, Gilardini Montani MS, Benedetti R, Arena A, D'Orazi G, Cirone M
International journal of molecular sciences 2022 Feb 18;23(4)
International journal of molecular sciences 2022 Feb 18;23(4)
Hypoxia-Preconditioned Extracellular Vesicles from Mesenchymal Stem Cells Improve Cartilage Repair in Osteoarthritis.
Zhang B, Tian X, Qu Z, Hao J, Zhang W
Membranes 2022 Feb 16;12(2)
Membranes 2022 Feb 16;12(2)
Exosomes derived from M2 type tumor-associated macrophages promote osimertinib resistance in non-small cell lung cancer through MSTRG.292666.16-miR-6836-5p-MAPK8IP3 axis.
Wan X, Xie B, Sun H, Gu W, Wang C, Deng Q, Zhou S
Cancer cell international 2022 Feb 15;22(1):83
Cancer cell international 2022 Feb 15;22(1):83
Regorafenib and reactive metabolite of sunitinib activate inflammasomes: Implications for multi tyrosine kinase inhibitor-Iiduced immune related adverse events.
Kato R, Ijiri Y
Die Pharmazie 2022 Feb 1;77(2):54-58
Die Pharmazie 2022 Feb 1;77(2):54-58
Exosomes derived from human umbilical cord mesenchymal stem cells protect against papain-induced emphysema by preventing apoptosis through activating VEGF-VEGFR2-mediated AKT and MEK/ERK pathways in rats.
Chen Q, Lin J, Deng Z, Qian W
Regenerative therapy 2022 Dec;21:216-224
Regenerative therapy 2022 Dec;21:216-224
Anserine and Carnosine Induce HSP70-Dependent H(2)S Formation in Endothelial Cells and Murine Kidney.
Wetzel C, Pfeffer T, Bulkescher R, Zemva J, Modafferi S, Polimeni A, Salinaro AT, Calabrese V, Schmitt CP, Peters V
Antioxidants (Basel, Switzerland) 2022 Dec 28;12(1)
Antioxidants (Basel, Switzerland) 2022 Dec 28;12(1)
Effect of miR-143-3p from Extracellular Vesicles of Porcine Uterine Luminal Fluid on Porcine Trophoblast Cells.
Ding Y, Hu Q, Gan J, Zang X, Gu T, Wu Z, Cai G, Hong L
Animals : an open access journal from MDPI 2022 Dec 2;12(23)
Animals : an open access journal from MDPI 2022 Dec 2;12(23)
Effects of the probiotic, Lactobacillus rhamnosus GG, on ulcer pathogenesis, HSP70 stress protein and nitric oxide levels in stress induced ulcer.
Isik M, Ozbayer C, Donmez DB, Colak E, Ustuner MC, Erol K, Degirmenci I
Biotechnic & histochemistry : official publication of the Biological Stain Commission 2022 Aug;97(6):449-460
Biotechnic & histochemistry : official publication of the Biological Stain Commission 2022 Aug;97(6):449-460
Human breast milk-derived exosomes through inhibiting AT II cell apoptosis to prevent bronchopulmonary dysplasia in rat lung.
Zhou Y, Liu Y, Xu G, Liu L, Li H, Li Y, Yin J, Wang X, Yu Z
Journal of cellular and molecular medicine 2022 Aug;26(15):4169-4182
Journal of cellular and molecular medicine 2022 Aug;26(15):4169-4182
Jianpi Huayu decoction inhibits the epithelial-mesenchymal transition of hepatocellular carcinoma cells by suppressing exosomal miR-23a-3p/Smad signaling.
Xie CF, Feng KL, Wang JN, Luo R, Fang CK, Zhang Y, Shen CP, Zhong C
Journal of ethnopharmacology 2022 Aug 10;294:115360
Journal of ethnopharmacology 2022 Aug 10;294:115360
The alleviative effect of thyroid hormone on cold stress-induced apotosis via HSP70 and mitochondrial apoptosis signal pathway in bovine Sertoli cells.
Zhang H, Huang H, Zheng P, Feng R, Wang X, Huang F, Ma M, Tian Y, Zhang G
Cryobiology 2022 Apr;105:63-70
Cryobiology 2022 Apr;105:63-70
Nicotinamide mononucleotide alleviates heat stress-induced oxidative stress and apoptosis in BMECs through reducing mitochondrial damage and endoplasmic reticulum stress.
Zeng HF, Xu J, Wang XL, Li SJ, Han ZY
Ecotoxicology and environmental safety 2022 Apr 15;235:113441
Ecotoxicology and environmental safety 2022 Apr 15;235:113441
Distinct Gene Expression Patterns of Two Heat Shock Protein 70 Members During Development, Diapause, and Temperature Stress in the Freshwater Crustacean Daphnia magna.
Chen L, Gómez R, Weiss LC
Frontiers in cell and developmental biology 2021;9:692517
Frontiers in cell and developmental biology 2021;9:692517
Exosomes Isolated From Bone Marrow Mesenchymal Stem Cells Exert a Protective Effect on Osteoarthritis via lncRNA LYRM4-AS1-GRPR-miR-6515-5p.
Wang X, Li Z, Cui Y, Cui X, Chen C, Wang Z
Frontiers in cell and developmental biology 2021;9:644380
Frontiers in cell and developmental biology 2021;9:644380
The Formation of Melanocyte Apoptotic Bodies in Vitiligo and the Relocation of Vitiligo Autoantigens under Oxidative Stress.
Tian J, Wang Y, Ding M, Zhang Y, Chi J, Wang T, Jiao B, Jian Z, Yi X, Huang Y, Liu L, Li K, Chen J, Wang G, Gao T, Li C, Li Q
Oxidative medicine and cellular longevity 2021;2021:7617839
Oxidative medicine and cellular longevity 2021;2021:7617839
Long Noncoding RNA RP11-115N4.1 Promotes Inflammatory Responses by Interacting With HNRNPH3 and Enhancing the Transcription of HSP70 in Unexplained Recurrent Spontaneous Abortion.
Liu M, Sun X, Zhu L, Zhu M, Deng K, Nie X, Mo H, Du T, Huang B, Hu L, Liang L, Wang D, Luo Y, Yi J, Zhang J, Zhong X, Cao C, Chen H
Frontiers in immunology 2021;12:717785
Frontiers in immunology 2021;12:717785
LncRNA FOXP4-AS1 Promotes Progression of Ewing Sarcoma and Is Associated With Immune Infiltrates.
Xiong J, Wu L, Huang L, Wu C, Liu Z, Deng W, Ma S, Zhou Z, Yu H, Cao K
Frontiers in oncology 2021;11:718876
Frontiers in oncology 2021;11:718876
Exogenous H(2) S prevents the nuclear translocation of PDC-E1 and inhibits vascular smooth muscle cell proliferation in the diabetic state.
Zhang L, Jiang X, Liu N, Li M, Kang J, Chen L, Tang J, Dong S, Lu F, Zhang W
Journal of cellular and molecular medicine 2021 Sep;25(17):8201-8214
Journal of cellular and molecular medicine 2021 Sep;25(17):8201-8214
Regulating immune memory and reversing tumor thermotolerance through a step-by-step starving-photothermal therapy.
Luo L, Qin B, Jiang M, Xie L, Luo Z, Guo X, Zhang J, Li X, Zhu C, Du Y, Peng L, You J
Journal of nanobiotechnology 2021 Sep 30;19(1):297
Journal of nanobiotechnology 2021 Sep 30;19(1):297
Differential Expression Pattern of Goat Uterine Fluids Extracellular Vesicles miRNAs during Peri-Implantation.
Xie Y, Liu G, Zang X, Hu Q, Zhou C, Li Y, Liu D, Hong L
Cells 2021 Sep 3;10(9)
Cells 2021 Sep 3;10(9)
SIRT3 protects bovine mammary epithelial cells from heat stress damage by activating the AMPK signaling pathway.
Sun XC, Wang Y, Zeng HF, Xi YM, Lin H, Han ZY, Chen KL
Cell death discovery 2021 Oct 21;7(1):304
Cell death discovery 2021 Oct 21;7(1):304
Repair of peripheral nerve defects by nerve grafts incorporated with extracellular vesicles from skin-derived precursor Schwann cells.
Yu M, Gu G, Cong M, Du M, Wang W, Shen M, Zhang Q, Shi H, Gu X, Ding F
Acta biomaterialia 2021 Oct 15;134:190-203
Acta biomaterialia 2021 Oct 15;134:190-203
Melatonin potentiates the cytotoxic effect of Neratinib in HER2(+) breast cancer through promoting endocytosis and lysosomal degradation of HER2.
Liu Z, Sang X, Wang M, Liu Y, Liu J, Wang X, Liu P, Cheng H
Oncogene 2021 Nov;40(44):6273-6283
Oncogene 2021 Nov;40(44):6273-6283
GADD45β stabilized by direct interaction with HSP72 ameliorates insulin resistance and lipid accumulation.
Dong Y, Ma N, Fan L, Yuan L, Wu Q, Gong L, Tao Z, Chen J, Ren J
Pharmacological research 2021 Nov;173:105879
Pharmacological research 2021 Nov;173:105879
Dendrobium officinale Polysaccharide Alleviates Intestinal Inflammation by Promoting Small Extracellular Vesicle Packaging of miR-433-3p.
Liu H, Liang J, Zhong Y, Xiao G, Efferth T, Georgiev MI, Vargas-De-La-Cruz C, Bajpai VK, Caprioli G, Liu J, Lin J, Wu H, Peng L, Li Y, Ma L, Xiao J, Wang Q
Journal of agricultural and food chemistry 2021 Nov 17;69(45):13510-13523
Journal of agricultural and food chemistry 2021 Nov 17;69(45):13510-13523
Lipidomic Profiling of Human Milk Derived Exosomes and Their Emerging Roles in the Prevention of Necrotizing Enterocolitis.
Chen W, Chen X, Qian Y, Wang X, Zhou Y, Yan X, Yu B, Yao S, Yu Z, Zhu J, Han S
Molecular nutrition & food research 2021 May;65(10):e2000845
Molecular nutrition & food research 2021 May;65(10):e2000845
Dihydromyricetin attenuates heat stress-induced apoptosis in dairy cow mammary epithelial cells through suppressing mitochondrial dysfunction.
Wang HL, Xing GD, Qian Y, Sun XF, Zhong JF, Chen KL
Ecotoxicology and environmental safety 2021 May;214:112078
Ecotoxicology and environmental safety 2021 May;214:112078
Cardiomyocyte contractile impairment in heart failure results from reduced BAG3-mediated sarcomeric protein turnover.
Martin TG, Myers VD, Dubey P, Dubey S, Perez E, Moravec CS, Willis MS, Feldman AM, Kirk JA
Nature communications 2021 May 19;12(1):2942
Nature communications 2021 May 19;12(1):2942
Cytokine Profile in Plasma Extracellular Vesicles of Parkinson's Disease and the Association with Cognitive Function.
Chan L, Chung CC, Chen JH, Yu RC, Hong CT
Cells 2021 Mar 9;10(3)
Cells 2021 Mar 9;10(3)
Hypoxic tumor-derived exosomal circular RNA SETDB1 promotes invasive growth and EMT via the miR-7/Sp1 axis in lung adenocarcinoma.
Xu L, Liao WL, Lu QJ, Zhang P, Zhu J, Jiang GN
Molecular therapy. Nucleic acids 2021 Mar 5;23:1078-1092
Molecular therapy. Nucleic acids 2021 Mar 5;23:1078-1092
Osteosarcoma-derived exosomal miR-501-3p promotes osteoclastogenesis and aggravates bone loss.
Lin L, Wang H, Guo W, He E, Huang K, Zhao Q
Cellular signalling 2021 Jun;82:109935
Cellular signalling 2021 Jun;82:109935
UBQLN2-HSP70 axis reduces poly-Gly-Ala aggregates and alleviates behavioral defects in the C9ORF72 animal model.
Zhang K, Wang A, Zhong K, Qi S, Wei C, Shu X, Tu WY, Xu W, Xia C, Xiao Y, Chen A, Bai L, Zhang J, Luo B, Wang W, Shen C
Neuron 2021 Jun 16;109(12):1949-1962.e6
Neuron 2021 Jun 16;109(12):1949-1962.e6
Dual roles of HSP70 chaperone HSPA1 in quality control of nascent and newly synthesized proteins.
Tian G, Hu C, Yun Y, Yang W, Dubiel W, Cheng Y, Wolf DA
The EMBO journal 2021 Jul 1;40(13):e106183
The EMBO journal 2021 Jul 1;40(13):e106183
Seminal exosomal miR-210-3p as a potential marker of Sertoli cell damage in Varicocele.
Ma Y, Zhou Y, Xiao Q, Zou SS, Zhu YC, Ping P, Chen XF
Andrology 2021 Jan;9(1):451-459
Andrology 2021 Jan;9(1):451-459
The Role and Mechanism of Exosomes from Umbilical Cord Mesenchymal Stem Cells in Inducing Osteogenesis and Preventing Osteoporosis.
Yahao G, Xinjia W
Cell transplantation 2021 Jan-Dec;30:9636897211057465
Cell transplantation 2021 Jan-Dec;30:9636897211057465
The EGFR-HSF1 axis accelerates the tumorigenesis of pancreatic cancer.
Qian W, Chen K, Qin T, Xiao Y, Li J, Yue Y, Zhou C, Ma J, Duan W, Lei J, Han L, Li L, Shen X, Wu Z, Ma Q, Wang Z
Journal of experimental & clinical cancer research : CR 2021 Jan 9;40(1):25
Journal of experimental & clinical cancer research : CR 2021 Jan 9;40(1):25
Hsp90 is involved in pseudorabies virus virion assembly via stabilizing major capsid protein VP5.
Zhang WJ, Wang RQ, Li LT, Fu W, Chen HC, Liu ZF
Virology 2021 Jan 15;553:70-80
Virology 2021 Jan 15;553:70-80
Spermine Protects Cardiomyocytes from High Glucose-Induced Energy Disturbance by Targeting the CaSR-gp78-Ubiquitin Proteasome System.
Wang Y, Wang Y, Li F, Zhang X, Li H, Yang G, Xu C, Wei C
Cardiovascular drugs and therapy 2021 Feb;35(1):73-85
Cardiovascular drugs and therapy 2021 Feb;35(1):73-85
Boron Attenuates Heat Stress-Induced Apoptosis by Inhibiting Endoplasmic Reticulum Stress in Mouse Granulosa Cells.
Xiong Y, Jin E, Yin Q, Che C, He S
Biological trace element research 2021 Feb;199(2):611-621
Biological trace element research 2021 Feb;199(2):611-621
Small extracellular vesicle-mediated Hsp70 intercellular delivery enhances breast cancer adriamycin resistance.
Hu W, Xu Z, Zhu S, Sun W, Wang X, Tan C, Zhang Y, Zhang G, Xu Y, Tang J
Free radical biology & medicine 2021 Feb 20;164:85-95
Free radical biology & medicine 2021 Feb 20;164:85-95
Exosomes secreted from mesenchymal stem cells mediate the regeneration of endothelial cells treated with rapamycin by delivering pro-angiogenic microRNAs.
Wang W, Zhao Y, Li H, Zhang Y, Jia X, Wang C, Zhu P, Wang J, Hou Y
Experimental cell research 2021 Feb 1;399(1):112449
Experimental cell research 2021 Feb 1;399(1):112449
SKP-SC-EVs Mitigate Denervated Muscle Atrophy by Inhibiting Oxidative Stress and Inflammation and Improving Microcirculation.
Wang W, Shen D, Zhang L, Ji Y, Xu L, Chen Z, Shen Y, Gong L, Zhang Q, Shen M, Gu X, Sun H
Antioxidants (Basel, Switzerland) 2021 Dec 28;11(1)
Antioxidants (Basel, Switzerland) 2021 Dec 28;11(1)
A Modified Nucleoside 6-Thio-2'-Deoxyguanosine Exhibits Antitumor Activity in Gliomas.
Yu S, Wei S, Savani M, Lin X, Du K, Mender I, Siteni S, Vasilopoulos T, Reitman ZJ, Ku Y, Wu D, Liu H, Tian M, Chen Y, Labrie M, Charbonneau CM, Sugarman E, Bowie M, Hariharan S, Waitkus M, Jiang W, McLendon RE, Pan E, Khasraw M, Walsh KM, Lu Y, Herlyn M, Mills G, Herbig U, Wei Z, Keir ST, Flaherty K, Liu L, Wu K, Shay JW, Abdullah K, Zhang G, Ashley DM
Clinical cancer research : an official journal of the American Association for Cancer Research 2021 Dec 15;27(24):6800-6814
Clinical cancer research : an official journal of the American Association for Cancer Research 2021 Dec 15;27(24):6800-6814
Exosomal miR-193b-5p as a regulator of LPS-induced inflammation in dairy cow mammary epithelial cells.
Xu H, Zhang T, Hu X, Xie Y, Wu R, Lian S, Wang J
In vitro cellular & developmental biology. Animal 2021 Aug;57(7):695-703
In vitro cellular & developmental biology. Animal 2021 Aug;57(7):695-703
Augmentation of the heat shock axis during exceptional longevity in Ames dwarf mice.
Trivedi R, Knopf B, Tripathi JK, Rakoczy S, Manocha GD, Brown-Borg H, Jurivich DA
GeroScience 2021 Aug;43(4):1921-1934
GeroScience 2021 Aug;43(4):1921-1934
Recovery from heat shock requires the microRNA pathway in Caenorhabditis elegans.
Pagliuso DC, Bodas DM, Pasquinelli AE
PLoS genetics 2021 Aug;17(8):e1009734
PLoS genetics 2021 Aug;17(8):e1009734
A novel Hsp70 inhibitor specifically targeting the cancer-related Hsp70-Bim protein-protein interaction.
Wang Z, Song T, Guo Z, Uwituze LB, Guo Y, Zhang H, Wang H, Zhang X, Pan H, Ji T, Yin F, Zhou S, Dai J, Zhang Z
European journal of medicinal chemistry 2021 Aug 5;220:113452
European journal of medicinal chemistry 2021 Aug 5;220:113452
Amiodarone, Unlike Dronedarone, Activates Inflammasomes via Its Reactive Metabolites: Implications for Amiodarone Adverse Reactions.
Kato R, Ijiri Y, Hayashi T
Chemical research in toxicology 2021 Aug 16;34(8):1860-1865
Chemical research in toxicology 2021 Aug 16;34(8):1860-1865
Tubocapsenolide A targets C-terminal cysteine residues of HSP90 to exert the anti-tumor effect.
Zhu D, Li S, Chen C, Wang S, Zhu J, Kong L, Luo J
Pharmacological research 2021 Apr;166:105523
Pharmacological research 2021 Apr;166:105523
Adipose-derived stem cell exosomes facilitate rotator cuff repair by mediating tendon-derived stem cells.
Fu G, Lu L, Pan Z, Fan A, Yin F
Regenerative medicine 2021 Apr;16(4):359-372
Regenerative medicine 2021 Apr;16(4):359-372
Construction of Smart Nanotheranostic Platform Bi-Ag@PVP: Multimodal CT/PA Imaging-Guided PDT/PTT for Cancer Therapy.
Zhou Z, Xie J, Ma S, Luo X, Liu J, Wang S, Chen Y, Yan J, Luo F
ACS omega 2021 Apr 27;6(16):10723-10734
ACS omega 2021 Apr 27;6(16):10723-10734
S-allyl cysteine ameliorates heat stress-induced oxidative stress by activating Nrf2/HO-1 signaling pathway in BMECs.
Wang Y, Wang HL, Xing GD, Qian Y, Zhong JF, Chen KL
Toxicology and applied pharmacology 2021 Apr 1;416:115469
Toxicology and applied pharmacology 2021 Apr 1;416:115469
Hepatitis A virus structural protein pX interacts with ALIX and promotes the secretion of virions and foreign proteins through exosome-like vesicles.
Jiang W, Ma P, Deng L, Liu Z, Wang X, Liu X, Long G
Journal of extracellular vesicles 2020;9(1):1716513
Journal of extracellular vesicles 2020;9(1):1716513
TRIM16 Promotes Osteogenic Differentiation of Human Periodontal Ligament Stem Cells by Modulating CHIP-Mediated Degradation of RUNX2.
Zhao Y, Zhai Q, Liu H, Xi X, Chen S, Liu D
Frontiers in cell and developmental biology 2020;8:625105
Frontiers in cell and developmental biology 2020;8:625105
An Eight-CircRNA Assessment Model for Predicting Biochemical Recurrence in Prostate Cancer.
Wang S, Su W, Zhong C, Yang T, Chen W, Chen G, Liu Z, Wu K, Zhong W, Li B, Mao X, Lu J
Frontiers in cell and developmental biology 2020;8:599494
Frontiers in cell and developmental biology 2020;8:599494
Reactive metabolite of gefitinib activates inflammasomes: implications for gefitinib-induced idiosyncratic reaction.
Kato R, Ijiri Y, Hayashi T, Uetrecht J
The Journal of toxicological sciences 2020;45(11):673-680
The Journal of toxicological sciences 2020;45(11):673-680
Ultraviolet B irradiation enhances the secretion of exosomes by human primary melanocytes and changes their exosomal miRNA profile.
Shen Z, Sun J, Shao J, Xu J
PloS one 2020;15(8):e0237023
PloS one 2020;15(8):e0237023
Hsp90 inhibitor HSP990 in very low dose upregulates EAAT2 and exerts potent antiepileptic activity.
Sha L, Chen T, Deng Y, Du T, Ma K, Zhu W, Shen Y, Xu Q
Theranostics 2020;10(18):8415-8429
Theranostics 2020;10(18):8415-8429
Extracellular vesicle-mediated delivery of miR-101 inhibits lung metastasis in osteosarcoma.
Zhang K, Dong C, Chen M, Yang T, Wang X, Gao Y, Wang L, Wen Y, Chen G, Wang X, Yu X, Zhang Y, Wang P, Shang M, Han K, Zhou Y
Theranostics 2020;10(1):411-425
Theranostics 2020;10(1):411-425
circFMN2 Sponges miR-1238 to Promote the Expression of LIM-Homeobox Gene 2 in Prostate Cancer Cells.
Shan G, Shao B, Liu Q, Zeng Y, Fu C, Chen A, Chen Q
Molecular therapy. Nucleic acids 2020 Sep 4;21:133-146
Molecular therapy. Nucleic acids 2020 Sep 4;21:133-146
Multifactorial Attenuation of the Murine Heat Shock Response With Age.
Jurivich DA, Manocha GD, Trivedi R, Lizakowski M, Rakoczy S, Brown-Borg H
The journals of gerontology. Series A, Biological sciences and medical sciences 2020 Sep 25;75(10):1846-1852
The journals of gerontology. Series A, Biological sciences and medical sciences 2020 Sep 25;75(10):1846-1852
UBE2T-regulated H2AX monoubiquitination induces hepatocellular carcinoma radioresistance by facilitating CHK1 activation.
Sun J, Zhu Z, Li W, Shen M, Cao C, Sun Q, Guo Z, Liu L, Wu D
Journal of experimental & clinical cancer research : CR 2020 Oct 21;39(1):222
Journal of experimental & clinical cancer research : CR 2020 Oct 21;39(1):222
CDK5RAP3, a Novel Nucleoplasmic Shuttle, Deeply Regulates HSF1-Mediated Heat Stress Response and Protects Mammary Epithelial Cells from Heat Injury.
Shen Y, Zou Y, Li J, Chen F, Li H, Cai Y
International journal of molecular sciences 2020 Nov 9;21(21)
International journal of molecular sciences 2020 Nov 9;21(21)
Small extracellular vesicle-bound vascular endothelial growth factor secreted by carcinoma-associated fibroblasts promotes angiogenesis in a bevacizumab-resistant manner.
Li J, Liu X, Zang S, Zhou J, Zhang F, Sun B, Qi D, Li X, Kong J, Jin D, Yang X, Luo Y, Lu Y, Lin B, Niu W, Liu T
Cancer letters 2020 Nov 1;492:71-83
Cancer letters 2020 Nov 1;492:71-83
Exogenous spermine attenuates rat diabetic cardiomyopathy via suppressing ROS-p53 mediated downregulation of calcium-sensitive receptor.
Wang Y, Chen J, Li S, Zhang X, Guo Z, Hu J, Shao X, Song N, Zhao Y, Li H, Yang G, Xu C, Wei C
Redox biology 2020 May;32:101514
Redox biology 2020 May;32:101514
Liver-derived exosome-laden lncRNA MT1DP aggravates cadmium-induced nephrotoxicity.
Gao M, Dong Z, Sun J, Liu W, Xu M, Li C, Zhu P, Yang X, Shang X, Wu Y, Liu S
Environmental pollution (Barking, Essex : 1987) 2020 Mar;258:113717
Environmental pollution (Barking, Essex : 1987) 2020 Mar;258:113717
Light-activated oxygen self-supplied starving therapy in near-infrared (NIR) window and adjuvant hyperthermia-induced tumor ablation with an augmented sensitivity.
Ren J, Zhang L, Zhang J, Zhang W, Cao Y, Xu Z, Cui H, Kang Y, Xue P
Biomaterials 2020 Mar;234:119771
Biomaterials 2020 Mar;234:119771
Heat Stress Impairs the Physiological Responses and Regulates Genes Coding for Extracellular Exosomal Proteins in Rat.
Dou J, Khan A, Khan MZ, Mi S, Wang Y, Yu Y, Wang Y
Genes 2020 Mar 13;11(3)
Genes 2020 Mar 13;11(3)
Exosomes carrying ALDOA and ALDH3A1 from irradiated lung cancer cells enhance migration and invasion of recipients by accelerating glycolysis.
Wang C, Xu J, Yuan D, Bai Y, Pan Y, Zhang J, Shao C
Molecular and cellular biochemistry 2020 Jun;469(1-2):77-87
Molecular and cellular biochemistry 2020 Jun;469(1-2):77-87
Tumor-Derived EV-Encapsulated miR-181b-5p Induces Angiogenesis to Foster Tumorigenesis and Metastasis of ESCC.
Wang Y, Lu J, Chen L, Bian H, Hu J, Li D, Xia C, Xu H
Molecular therapy. Nucleic acids 2020 Jun 5;20:421-437
Molecular therapy. Nucleic acids 2020 Jun 5;20:421-437
Various Anti-HSPA2 Antibodies Yield Different Results in Studies on Cancer-Related Functions of Heat Shock Protein A2.
Scieglinska D, Sojka DR, Gogler-Pigłowska A, Chumak V, Krawczyk Z
International journal of molecular sciences 2020 Jun 16;21(12)
International journal of molecular sciences 2020 Jun 16;21(12)
Rosmarinic acid exerts a neuroprotective effect on spinal cord injury by suppressing oxidative stress and inflammation via modulating the Nrf2/HO-1 and TLR4/NF-κB pathways.
Ma Z, Lu Y, Yang F, Li S, He X, Gao Y, Zhang G, Ren E, Wang Y, Kang X
Toxicology and applied pharmacology 2020 Jun 15;397:115014
Toxicology and applied pharmacology 2020 Jun 15;397:115014
Circulating Exosomes From Lipopolysaccharide-Induced Ards Mice Trigger Endoplasmic Reticulum Stress in Lung Tissue.
Tang X, Yu Q, Wen X, Qi D, Peng J, He J, Deng W, Zhu T, Zhao Y, Wang D
Shock (Augusta, Ga.) 2020 Jul;54(1):110-118
Shock (Augusta, Ga.) 2020 Jul;54(1):110-118
CaCBL1 Acts as a Positive Regulator in Pepper Response to Ralstonia solanacearum.
Shen L, Yang S, Yang F, Guan D, He S
Molecular plant-microbe interactions : MPMI 2020 Jul;33(7):945-957
Molecular plant-microbe interactions : MPMI 2020 Jul;33(7):945-957
LASP1 promotes proliferation, metastasis, invasion in head and neck squamous cell carcinoma and through direct interaction with HSPA1A.
Chen Q, Wu K, Qin X, Yu Y, Wang X, Wei K
Journal of cellular and molecular medicine 2020 Jan;24(2):1626-1639
Journal of cellular and molecular medicine 2020 Jan;24(2):1626-1639
Selenium Attenuates Chronic Heat Stress-Induced Apoptosis via the Inhibition of Endoplasmic Reticulum Stress in Mouse Granulosa Cells.
Xiong Y, Yin Q, Jin E, Chen H, He S
Molecules (Basel, Switzerland) 2020 Jan 28;25(3)
Molecules (Basel, Switzerland) 2020 Jan 28;25(3)
Enterovirus A71 capsid protein VP1 increases blood-brain barrier permeability and virus receptor vimentin on the brain endothelial cells.
Wang W, Sun J, Wang N, Sun Z, Ma Q, Li J, Zhang M, Xu J
Journal of neurovirology 2020 Feb;26(1):84-94
Journal of neurovirology 2020 Feb;26(1):84-94
Extracellular Vesicles from Hyperammonemic Rats Induce Neuroinflammation and Motor Incoordination in Control Rats.
Izquierdo-Altarejos P, Cabrera-Pastor A, Gonzalez-King H, Montoliu C, Felipo V
Cells 2020 Feb 28;9(3)
Cells 2020 Feb 28;9(3)
Hepatic DNAJB9 Drives Anabolic Biasing to Reduce Steatosis and Obesity.
Sun F, Liao Y, Qu X, Xiao X, Hou S, Chen Z, Huang H, Li P, Fu S
Cell reports 2020 Feb 11;30(6):1835-1847.e9
Cell reports 2020 Feb 11;30(6):1835-1847.e9
Extracellular vesicles from skin precursor-derived Schwann cells promote axonal outgrowth and regeneration of motoneurons via Akt/mTOR/p70S6K pathway.
Wu X, Wang L, Cong M, Shen M, He Q, Ding F, Shi H
Annals of translational medicine 2020 Dec;8(24):1640
Annals of translational medicine 2020 Dec;8(24):1640
Heat stress activates YAP/TAZ to induce the heat shock transcriptome.
Luo M, Meng Z, Moroishi T, Lin KC, Shen G, Mo F, Shao B, Wei X, Zhang P, Wei Y, Guan KL
Nature cell biology 2020 Dec;22(12):1447-1459
Nature cell biology 2020 Dec;22(12):1447-1459
Antagomirs targeting miR-142-5p attenuate pilocarpine-induced status epilepticus in mice.
Zhang H, Lian Y, Xie N, Cheng X, Chen C, Xu H, Zheng Y
Experimental cell research 2020 Aug 15;393(2):112089
Experimental cell research 2020 Aug 15;393(2):112089
Heat stress induces apoptosis through disruption of dynamic mitochondrial networks in dairy cow mammary epithelial cells.
Chen KL, Wang HL, Jiang LZ, Qian Y, Yang CX, Chang WW, Zhong JF, Xing GD
In vitro cellular & developmental biology. Animal 2020 Apr;56(4):322-331
In vitro cellular & developmental biology. Animal 2020 Apr;56(4):322-331
Adipose-derived exosomes protect the pulmonary endothelial barrier in ventilator-induced lung injury by inhibiting the TRPV4/Ca(2+) signaling pathway.
Yu Q, Wang D, Wen X, Tang X, Qi D, He J, Zhao Y, Deng W, Zhu T
American journal of physiology. Lung cellular and molecular physiology 2020 Apr 1;318(4):L723-L741
American journal of physiology. Lung cellular and molecular physiology 2020 Apr 1;318(4):L723-L741
Hypoxia preconditioned renal tubular epithelial cell-derived extracellular vesicles alleviate renal ischaemia-reperfusion injury mediated by the HIF-1α/Rab22 pathway and potentially affected by microRNAs.
Zhang L, Liu H, Xu K, Ling Z, Huang Y, Hu Q, Lu K, Liu C, Wang Y, Liu N, Zhang X, Xu B, Wu J, Chen S, Zhang G, Chen M
International journal of biological sciences 2019;15(6):1161-1176
International journal of biological sciences 2019;15(6):1161-1176
(-)-Oleocanthal and (-)-oleocanthal-rich olive oils induce lysosomal membrane permeabilization in cancer cells.
Goren L, Zhang G, Kaushik S, Breslin PAS, Du YN, Foster DA
PloS one 2019;14(8):e0216024
PloS one 2019;14(8):e0216024
The Capsid Protein VP1 of Coxsackievirus B Induces Cell Cycle Arrest by Up-Regulating Heat Shock Protein 70.
Wang Y, Zhao S, Chen Y, Wang T, Dong C, Wo X, Zhang J, Dong Y, Xu W, Feng X, Qu C, Wang Y, Zhong Z, Zhao W
Frontiers in microbiology 2019;10:1633
Frontiers in microbiology 2019;10:1633
Mapping Interactome Networks of DNAJC11, a Novel Mitochondrial Protein Causing Neuromuscular Pathology in Mice.
Violitzi F, Perivolidi VI, Thireou T, Grivas I, Haralambous S, Samiotaki M, Panayotou G, Douni E
Journal of proteome research 2019 Nov 1;18(11):3896-3912
Journal of proteome research 2019 Nov 1;18(11):3896-3912
Hepatitis B virus-regulated growth of liver cancer cells occurs through the microRNA-340-5p-activating transcription factor 7-heat shock protein A member 1B axis.
Song F, Wei M, Wang J, Liu Y, Guo M, Li X, Luo J, Zhou J, Wang M, Guo D, Chen L, Sun G
Cancer science 2019 May;110(5):1633-1643
Cancer science 2019 May;110(5):1633-1643
An acquired scaffolding function of the DNAJ-PKAc fusion contributes to oncogenic signaling in fibrolamellar carcinoma.
Turnham RE, Smith FD, Kenerson HL, Omar MH, Golkowski M, Garcia I, Bauer R, Lau HT, Sullivan KM, Langeberg LK, Ong SE, Riehle KJ, Yeung RS, Scott JD
eLife 2019 May 7;8
eLife 2019 May 7;8
The circRNA circPTPRA suppresses epithelial-mesenchymal transitioning and metastasis of NSCLC cells by sponging miR-96-5p.
Wei S, Zheng Y, Jiang Y, Li X, Geng J, Shen Y, Li Q, Wang X, Zhao C, Chen Y, Qian Z, Zhou J, Li W
EBioMedicine 2019 Jun;44:182-193
EBioMedicine 2019 Jun;44:182-193
Bioinspired extracellular vesicles embedded with black phosphorus for molecular recognition-guided biomineralization.
Wang Y, Hu X, Zhang L, Zhu C, Wang J, Li Y, Wang Y, Wang C, Zhang Y, Yuan Q
Nature communications 2019 Jun 27;10(1):2829
Nature communications 2019 Jun 27;10(1):2829
Elevated levels of circulating ITIH4 are associated with hepatocellular carcinoma with nonalcoholic fatty liver disease: from pig model to human study.
Nakamura N, Hatano E, Iguchi K, Sato M, Kawaguchi H, Ohtsu I, Sakurai T, Aizawa N, Iijima H, Nishiguchi S, Tomono T, Okuda Y, Wada S, Seo S, Taura K, Uemoto S, Ikegawa M
BMC cancer 2019 Jun 25;19(1):621
BMC cancer 2019 Jun 25;19(1):621
The up-regulation of two identified wound healing specific proteins-HSP70 and lysozyme in regenerated Eisenia fetida through transcriptome analysis.
Yang Y, Sun Y, Zhang N, Li J, Zhang C, Duan X, Ding Y, Zhao R, Zheng Z, Geng D, Sun Y
Journal of ethnopharmacology 2019 Jun 12;237:64-73
Journal of ethnopharmacology 2019 Jun 12;237:64-73
The exosome-like vesicles from osteoarthritic chondrocyte enhanced mature IL-1β production of macrophages and aggravated synovitis in osteoarthritis.
Ni Z, Kuang L, Chen H, Xie Y, Zhang B, Ouyang J, Wu J, Zhou S, Chen L, Su N, Tan Q, Luo X, Chen B, Chen S, Yin L, Huang H, Du X, Chen L
Cell death & disease 2019 Jul 8;10(7):522
Cell death & disease 2019 Jul 8;10(7):522
HMGB1-mediated differential response on hippocampal neurotransmitter disorder and neuroinflammation in adolescent male and female mice following cold exposure.
Xu B, Zang SC, Li SZ, Guo JR, Wang JF, Wang D, Zhang LP, Yang HM, Lian S
Brain, behavior, and immunity 2019 Feb;76:223-235
Brain, behavior, and immunity 2019 Feb;76:223-235
Exosomes from glioma cells induce a tumor-like phenotype in mesenchymal stem cells by activating glycolysis.
Ma Z, Cui X, Lu L, Chen G, Yang Y, Hu Y, Lu Y, Cao Z, Wang Y, Wang X
Stem cell research & therapy 2019 Feb 15;10(1):60
Stem cell research & therapy 2019 Feb 15;10(1):60
Design, synthesis and molecular mechanisms of novel dual inhibitors of heat shock protein 90/phosphoinositide 3-kinase alpha (Hsp90/PI3Kα) against cutaneous melanoma.
Qin F, Wang Y, Jiang X, Wang Y, Zhang N, Wen X, Wang L, Jiang Q, He G
Journal of enzyme inhibition and medicinal chemistry 2019 Dec;34(1):909-926
Journal of enzyme inhibition and medicinal chemistry 2019 Dec;34(1):909-926
Necroptosis promotes autophagy-dependent upregulation of DAMP and results in immunosurveillance.
Lin SY, Hsieh SY, Fan YT, Wei WC, Hsiao PW, Tsai DH, Wu TS, Yang NS
Autophagy 2018;14(5):778-795
Autophagy 2018;14(5):778-795
Inhibition of Heat Shock Protein 90 by 17-AAG Reduces Inflammation via P2X7 Receptor/NLRP3 Inflammasome Pathway and Increases Neurogenesis After Subarachnoid Hemorrhage in Mice.
Zuo Y, Wang J, Liao F, Yan X, Li J, Huang L, Liu F
Frontiers in molecular neuroscience 2018;11:401
Frontiers in molecular neuroscience 2018;11:401
Circulating exosomes contain protein biomarkers of metastatic non-small-cell lung cancer.
Wang N, Song X, Liu L, Niu L, Wang X, Song X, Xie L
Cancer science 2018 May;109(5):1701-1709
Cancer science 2018 May;109(5):1701-1709
A proteomic approach reveals the differential protein expression in Drosophila melanogaster treated with red ginseng extract (Panax ginseng).
Liu QX, Zhang W, Wang J, Hou W, Wang YP
Journal of ginseng research 2018 Jul;42(3):343-351
Journal of ginseng research 2018 Jul;42(3):343-351
Curcumin inhibits liver cancer by inhibiting DAMP molecule HSP70 and TLR4 signaling.
Ren B, Luo S, Tian X, Jiang Z, Zou G, Xu F, Yin T, Huang Y, Liu J
Oncology reports 2018 Aug;40(2):895-901
Oncology reports 2018 Aug;40(2):895-901
Effects of Boron Supplementation on Expression of Hsp70 in the Spleen of African Ostrich.
Haseeb K, Wang J, Xiao K, Yang KL, Sun PP, Wu XT, Luo Y, Song H, Liu HZ, Zhong JM, Peng KM
Biological trace element research 2018 Apr;182(2):317-327
Biological trace element research 2018 Apr;182(2):317-327
Uncoupling of Metabolic Health from Longevity through Genetic Alteration of Adipose Tissue Lipid-Binding Proteins.
Charles KN, Li MD, Engin F, Arruda AP, Inouye K, Hotamisligil GS
Cell reports 2017 Oct 10;21(2):393-402
Cell reports 2017 Oct 10;21(2):393-402
HSP90 recognizes the N-terminus of huntingtin involved in regulation of huntingtin aggregation by USP19.
He WT, Xue W, Gao YG, Hong JY, Yue HW, Jiang LL, Hu HY
Scientific reports 2017 Nov 1;7(1):14797
Scientific reports 2017 Nov 1;7(1):14797
Calcium sensing receptor protects high glucose-induced energy metabolism disorder via blocking gp78-ubiquitin proteasome pathway.
Wang Y, Gao P, Wei C, Li H, Zhang L, Zhao Y, Wu B, Tian Y, Zhang W, Wu L, Wang R, Xu C
Cell death & disease 2017 May 18;8(5):e2799
Cell death & disease 2017 May 18;8(5):e2799
A comparative proteomic analysis reveals important proteins for the fertilization and early embryonic development of the oyster Crassostrea gigas.
Huang X, Huan P, Liu B
Proteomics 2017 Jan;17(1-2)
Proteomics 2017 Jan;17(1-2)
Multifunctional WS(2) @Poly(ethylene imine) Nanoplatforms for Imaging Guided Gene-Photothermal Synergistic Therapy of Cancer.
Zhang C, Yong Y, Song L, Dong X, Zhang X, Liu X, Gu Z, Zhao Y, Hu Z
Advanced healthcare materials 2016 Nov;5(21):2776-2787
Advanced healthcare materials 2016 Nov;5(21):2776-2787
Interferon α Induces the Apoptosis of Cervical Cancer HeLa Cells by Activating both the Intrinsic Mitochondrial Pathway and Endoplasmic Reticulum Stress-Induced Pathway.
Shi WY, Cao C, Liu L
International journal of molecular sciences 2016 Nov 2;17(11)
International journal of molecular sciences 2016 Nov 2;17(11)
Modification of the hTERT promoter by heat shock elements enhances the efficiency and specificity of cancer targeted gene therapy.
Wang X, Zhou P, Sun X, Wei G, Zhang L, Wang H, Yao J, Jia P, Zheng J
International journal of hyperthermia : the official journal of European Society for Hyperthermic Oncology, North American Hyperthermia Group 2016 May;32(3):244-53
International journal of hyperthermia : the official journal of European Society for Hyperthermic Oncology, North American Hyperthermia Group 2016 May;32(3):244-53
Changes in gene expression and content of Hsp70 and Hsp90 in striated muscles of mice after 30-day space flight on the biosatellite Bion-M1.
Gritsyna YV, Abdusalamova ZR, Vikhlyantsev IM, Ulanova AD, Shenkman BS, Podlubnaya ZA, Kozlovskaya IB
Doklady. Biochemistry and biophysics 2015;463:199-202
Doklady. Biochemistry and biophysics 2015;463:199-202
Identification of Hsf1 as a novel androgen receptor-regulated gene in mouse Sertoli cells.
Yang L, Wang Y, Zhang Q, Lai Y, Li C, Zhang Q, Huang W, Duan Y, Jiang Z, Li X, Cai Z, Mou L, Gui Y
Molecular reproduction and development 2014 Jun;81(6):514-23
Molecular reproduction and development 2014 Jun;81(6):514-23
Role of the nucleus tractus solitarii in the protection of pre-moxibustion on gastric mucosal lesions.
Peng L, Liu M, Chang X, Yang Z, Yi S, Yan J, Peng Y
Neural regeneration research 2014 Jan 15;9(2):198-204
Neural regeneration research 2014 Jan 15;9(2):198-204
Effects of pre-moxibustion at Zusanli (ST36) on heat shock protein 70 expression in rats with gastric mucosal lesions after neurotomy.
Peng L, Liu M, Chang X, Yang Z, Yi S, Yan J, Peng Y
Neural regeneration research 2012 Oct 25;7(30):2370-6
Neural regeneration research 2012 Oct 25;7(30):2370-6
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Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- The HSP70 antibody from Proteintech is a rabbit polyclonal antibody to a recombinant protein of human HSP70. This antibody recognizes human,mouse,rat antigen. The HSP70 antibody has been validated for the following applications: ELISA, IHC, WB, IF analysis.
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- Immunofluorescent analysis of HepG2 cells, using HSPA1A antibody 10995-1-AP at 1:50 dilution and Rhodamine-labeled goat anti-rabbit IgG (red). Blue pseudocolor = DAPI (fluorescent DNA dye).
- Sample type
- cell line
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- Immunohistochemical of paraffin-embedded human prostate cancer using 10995-1-AP(HSP70 antibody) at dilution of 1:100 (under 10x lens)
- Sample type
- tissue
