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- References [233]
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- Product number
- 10995-1-AP - Provider product page
- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#10995-1-AP, RRID:AB_2264230
- Product name
- HSP70 antibody
- Antibody type
- Polyclonal
- Description
- HSP70 antibody (Cat. #10995-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse, rat and has been validated for the following applications: FC, IF, IHC, IP, WB, ELISA.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references An ATP13A1-assisted topogenesis pathway for folding multi-spanning membrane proteins.
A combination of PD-L1-targeted IL-15 mRNA nanotherapy and ultrasound-targeted microbubble destruction for tumor immunotherapy.
Selenomethionine alleviates chronic heat stress-induced breast muscle injury and poor meat quality in broilers via relieving mitochondrial dysfunction and endoplasmic reticulum stress.
Bi(2)S(3)/Ti(3)C(2)-TPP nano-heterostructures induced by near-infrared for photodynamic therapy combined with photothermal therapy on hypoxic tumors.
L-Theanine alleviates heat stress through modulation of gut microbiota and immunity.
Plasma extracellular vesicle synaptic proteins as biomarkers of clinical progression in patients with Parkinson's disease.
The mitochondrial UPR induced by ATF5 attenuates intervertebral disc degeneration via cooperating with mitophagy.
Ponicidin-induced conformational changes of HSP90 regulates the MAPK pathway to relieve ulcerative colitis.
Reactive metabolite of trovafloxacin activates inflammasomes: Implications for trovafloxacin-induced liver injury.
Engineered Luminescent Oncolytic Vaccinia Virus Activation of Photodynamic-Immune Combination Therapy for Colorectal Cancer.
Effects of spinal cord injury associated exosomes delivered tRF-41 on the progression of spinal cord injury progression.
Extracellular vesicles separated from goat milk by differential centrifugation coupled with sodium citrate pretreatments.
Ambra1 in exosomes secreted by HK-2 cells damaged by supersaturated oxalate induce mitophagy and autophagy-ferroptosis in normal HK-2 cells to participate in the occurrence of kidney stones.
Huc-MSC-derived exosomal miR-144 alleviates inflammation in LPS-induced preeclampsia-like pregnant rats via the FosB/Flt-1 pathway.
Deep learning enables the discovery of a novel cuproptosis-inducing molecule for the inhibition of hepatocellular carcinoma.
Differential Proteomic Profiles of Coronary Serum Exosomes in Acute Myocardial Infarction Patients with or Without Diabetes Mellitus: ANGPTL6 Accelerates Regeneration of Endothelial Cells Treated with Rapamycin via MAPK Pathways.
Disrupted HSF1 regulation in normal and exceptional brain aging.
CircMTA2 Drives Gastric Cancer Progression through Suppressing MTA2 Degradation via Interacting with UCHL3.
Recruitment of BAG2 to DNAJ-PKAc scaffolds promotes cell survival and resistance to drug-induced apoptosis in fibrolamellar carcinoma.
Protein phosphatase 1 regulatory subunit 15 A promotes translation initiation and induces G2M phase arrest during cuproptosis in cancers.
Data on mitochondrial respiratory function in skeletal muscle of adult male mice in response to 3-weeks heat stress.
Dual RNA sequencing of Helicobacter pylori and host cell transcriptomes reveals ontologically distinct host-pathogen interaction.
Quantitative Measurement of Transthyretin Mistargeting by Proximity Labeling and Parallel Reaction Monitoring.
Cuproptosis enhances docetaxel chemosensitivity by inhibiting autophagy via the DLAT/mTOR pathway in prostate cancer.
Exploiting immunostimulatory mechanisms of immunogenic cell death to develop membrane-encapsulated nanoparticles as a potent tumor vaccine.
Fluorescence Tracking of Small Extracellular Vesicles In Vivo.
Quantitative proteomic analysis of local and systemic extracellular vesicles during Eimeria falciformis infectious cycle in the host.
USP14 Positively Modulates Head and Neck Squamous Carcinoma Tumorigenesis and Potentiates Heat Shock Pathway through HSF1 Stabilization.
Evaluation the role of cuproptosis-related genes in the pathogenesis, diagnosis and molecular subtypes identification of atherosclerosis.
Changes in the components of salivary exosomes due to initial periodontal therapy.
Targeting TNFAIP2 induces immunogenic cell death and sensitizes glioblastoma multiforme to anti-PD-1 therapy.
Phenyl dialkynylcarbinols, a Bioinspired Series of Synthetic Antitumor Acetylenic Lipids.
Tumor-repopulating cell-derived microparticles elicit cascade amplification of chemotherapy-induced antitumor immunity to boost anti-PD-1 therapy.
Effective myocardial infarction treatment by targeted accumulation of Sulforaphane using porous magnetic silica nanoparticles.
M2 macrophage exosomal LINC01001 promotes non-small cell lung cancer development by affecting METTL3 and glycolysis pathway.
Nuclear import carrier Hikeshi cooperates with HSP70 to promote murine oligodendrocyte differentiation and CNS myelination.
The proteomics analysis of extracellular vesicles revealed the possible function of heat shock protein 60 in Helicobacter pylori infection.
The HDAC inhibitor HFY-4A improves TUSC2 transcription to induce immunogenic cell death in breast cancer.
Pre-Induced ICD Membrane-Coated Carrier-Free Nanoparticles for the Personalized Lung Cancer Immunotherapy.
SIRT2 regulates extracellular vesicle-mediated liver-bone communication.
miR-27a-3p relieves heat stress-induced mitochondrial damage and aberrant milk protein synthesis through MEK/ERK pathway in BMECs.
Bone mesenchymal stem cell-derived exosomes involved co-delivery and synergism effect with icariin via mussel-inspired multifunctional hydrogel for cartilage protection.
Viral subversion of selective autophagy is critical for biogenesis of virus replication organelles.
Exosomes from tubular epithelial cells undergoing epithelial-to-mesenchymal transition promote renal fibrosis by M1 macrophage activation.
HSPA1A ameliorated spinal cord injury in rats by inhibiting apoptosis to exert neuroprotective effects.
Taxol‑resistant breast cancer cell‑derived exosome‑delivered miR‑187‑5p regulates the growth of breast cancer cells via ABCD2 and Wnt/β‑catenin signaling.
PTEN Deficiency Facilitates Exosome Secretion and Metastasis in Cholangiocarcinoma by Impairing TFEB-mediated Lysosome Biogenesis.
A curcumin analogue GO-Y030 depletes cancer stem cells by inhibiting the interaction between the HSP70/HSP40 complex and its substrates.
Cytokine profiles of plasma extracellular vesicles as progression biomarkers in Parkinson's disease.
Extracellular vesicles from Zika virus-infected cells display viral E protein that binds ZIKV-neutralizing antibodies to prevent infection enhancement.
Near-Infrared Phototheranostic Iron Pyrite Nanocrystals Simultaneously Induce Dual Cell Death Pathways via Enhanced Fenton Reactions in Triple-Negative Breast Cancer.
A cytosolic surveillance mechanism activates the mitochondrial UPR.
Recruitment of BAG2 to DNAJ-PKAc scaffolds promotes cell survival and resistance to drug-induced apoptosis in fibrolamellar carcinoma.
Albumosomes formed by cytoplasmic pre-folding albumin maintain mitochondrial homeostasis and inhibit nonalcoholic fatty liver disease.
Dextran 40 hybrid biomimetic bismuth-nanoflower designed for NIR II-triggered hypoxic tumor thermoradiotherapy via macrophage escape.
Carnosinase-1 Knock-Out Reduces Kidney Fibrosis in Type-1 Diabetic Mice on High Fat Diet.
Long noncoding RNA HITT coordinates with RGS2 to inhibit PD-L1 translation in T cell immunity.
Control of SOX2 protein stability and tumorigenic activity by E3 ligase CHIP in esophageal cancer cells.
Combination therapy with BMSCs‑exosomes and porous tantalum for the repair of femur supracondylar defects.
Roles of hypoxic environment and M2 macrophage-derived extracellular vesicles on the progression of non-small cell lung cancer.
Cellular Exposure to Chloroacetanilide Herbicides Induces Distinct Protein Destabilization Profiles.
Quantitative Measurement of Secretory Protein Mistargeting by Proximity Labeling and Parallel Reaction Monitoring.
Lysine butyrylation of HSP90 regulated by KAT8 and HDAC11 confers chemoresistance.
Cardiac myofibrillogenesis is spatiotemporally modulated by the molecular chaperone UNC45B.
Extracellular vesicles from mesenchymal stem cells reduce neuroinflammation in hippocampus and restore cognitive function in hyperammonemic rats.
Exosomal microRNAs regulate the heat stress response in sea cucumber Apostichopus japonicus.
iASPP suppression mediates terminal UPR and improves BRAF-inhibitor sensitivity of colon cancers.
Hypoxia aggravates the burden of yellowstripe goby (Mugilogobius chulae) under atorvastatin exposure.
lncRNA SND1-IT1 delivered via intracerebral hemorrhage-derived exosomes affect the growth of human microglia by regulating the miR-124-3p/MTF1 axis.
Exosomes Derived from AT2R-Overexpressing BMSC Prevent Restenosis After Carotid Artery Injury by Attenuating the Injury-Induced Neointimal Hyperplasia.
Distinctive chaperonopathy in skeletal muscle associated with the dominant variant in DNAJB4.
Sex-Inclined Piwi-Interacting RNAs in Serum Exosomes for Sex Determination in the Greater Amberjack (Seriola dumerili).
Negatively charged bladder acellular matrix loaded with positively charged adipose-derived mesenchymal stem cell-derived small extracellular vesicles for bladder tissue engineering.
Tryptophan alleviates intestinal damage through regulating necroptosis and TLR4/NOD signaling pathways in pigs after lipopolysaccharide challenge.
Tryptophan alleviates lipopolysaccharide-induced liver injury and inflammation by modulating necroptosis and pyroptosis signaling pathways in piglets.
MiR-223-3p overexpressed adipose mesenchymal stem cell-derived exosomes promote wound healing via targeting MAPK10.
Caspase-9 inhibition triggers Hsp90-based chemotherapy-mediated tumor intrinsic innate sensing and enhances antitumor immunity.
Betaine ameliorates heat stress-induced apoptosis by affecting oxidative and endoplasmic reticulum stress in mouse Leydig cells.
Dysregulated Autophagy and Sarcomere Dysfunction in Patients With Heart Failure With Co-Occurrence of P63A and P380S BAG3 Variants.
Integrated bioinformatics and experiment revealed that cuproptosis is the potential common pathogenesis of three kinds of primary cardiomyopathy.
Mechanism of non-steroidal anti-androgen-induced liver injury: Reactive metabolites of flutamide and bicalutamide activate inflammasomes.
Exosomal PGAM1 promotes prostate cancer angiogenesis and metastasis by interacting with ACTG1.
Tumor-Associated Extracellular Microvesicles with Fluorine-Modified Carbohydrate Antigens Trigger a Stronger Antitumor Immune Response.
Effects of diazoxide on streptozotocin induced β cell damage via HSP70/HSP90/TLR4/AMPK signaling pathways.
Degradation of neurodegenerative disease-associated TDP-43 aggregates and oligomers via a proteolysis-targeting chimera.
Differentially Expressed microRNAs in Peritoneal Dialysis Effluent-Derived Exosomes from the Patients with Ultrafiltration Failure.
Antimicrobial Effect of Extracellular Vesicles Derived From Human Oral Mucosal Epithelial Cells on Candida albicans.
Exosome-transmitted miR-3124-5p promotes cholangiocarcinoma development via targeting GDF11.
PINK1-Dependent Mitophagy Reduced Endothelial Hyperpermeability and Cell Migration Capacity Under Simulated Microgravity.
HucMSC-Ex carrying miR-203a-3p.2 ameliorates colitis through the suppression of caspase11/4-induced macrophage pyroptosis.
Depletion of serum-derived exosomes aggravates heat stress-induced damage of bovine mammary epithelial cells.
c-Myc Sustains Pancreatic Cancer Cell Survival and mutp53 Stability through the Mevalonate Pathway.
Integrated Analysis of Transcriptome and microRNA Profile Reveals the Toxicity of Euphorbia Factors toward Human Colon Adenocarcinoma Cell Line Caco-2.
Defective Human SRP Induces Protein Quality Control and Triggers Stress Response.
Activation of the Chemokine Receptor CCR1 and Preferential Recruitment of Gαi Suppress RSV Replication: Implications for Developing Novel Respiratory Syncytial Virus Treatment Strategies.
Design, synthesis, and biological evaluation of novel dual inhibitors of heat shock protein 90/mammalian target of rapamycin (Hsp90/mTOR) against bladder cancer cells.
Exosome-derived FGD5-AS1 promotes tumor-associated macrophage M2 polarization-mediated pancreatic cancer cell proliferation and metastasis.
SIRT4 Expression Ameliorates the Detrimental Effect of Heat Stress via AMPK/mTOR Signaling Pathway in BMECs.
BAG3 protects chondrocytes against lumbar facet joint osteoarthritis by regulating autophagy and apoptosis.
Class 3 phosphoinositide 3-kinase promotes hepatic glucocorticoid receptor stability and transcriptional activity.
Triptolide promotes degradation of the unfolded gain-of-function Tp53(R175H/Y220C) mutant protein by initiating heat shock protein 70 transcription in non-small cell lung cancer.
Inhibition of the CDK2 and Cyclin A complex leads to autophagic degradation of CDK2 in cancer cells.
Engineered exosome as targeted lncRNA MEG3 delivery vehicles for osteosarcoma therapy.
In situ injectable hydrogel-loaded drugs induce anti-tumor immune responses in melanoma immunochemotherapy.
LONP1-mediated mitochondrial quality control safeguards metabolic shifts in heart development.
SUMO2-mediated SUMOylation of SH3GLB1 promotes ionizing radiation-induced hypertrophic cardiomyopathy through mitophagy activation.
CircEZH2/miR-133b/IGF2BP2 aggravates colorectal cancer progression via enhancing the stability of m(6)A-modified CREB1 mRNA.
Exosomal tRF-Leu-AAG-001 derived from mast cell as a potential non-invasive diagnostic biomarker for endometriosis.
Comparative transcriptome and Lipidome analyses suggest a lipid droplet-specific response to heat exposure of brown adipose tissue in normal and obese mice.
Single-cell analysis of human basal cell carcinoma reveals novel regulators of tumor growth and the tumor microenvironment.
Targeted Analysis of HSP70 Isoforms in Human Spermatozoa in the Context of Capacitation and Motility.
Eimeria falciformis secretes extracellular vesicles to modulate proinflammatory response during interaction with mouse intestinal epithelial cells.
miR-126-3p containing exosomes derived from human umbilical cord mesenchymal stem cells promote angiogenesis and attenuate ovarian granulosa cell apoptosis in a preclinical rat model of premature ovarian failure.
Magnetic hyperthermia induces effective and genuine immunogenic tumor cell death with respect to exogenous heating.
Monitoring Protein Import into the Endoplasmic Reticulum in Living Cells with Proximity Labeling.
Fine-Tuning of Cholesterol Homeostasis Controls Erythroid Differentiation.
PKM2 compensates for proteasome dysfunction by mediating the formation of the CHIP-HSP70-BAG3 complex and the aggregation of ubiquitinated proteins.
Pharmacological inhibition of BAG3-HSP70 with the proposed cancer therapeutic JG-98 is toxic for cardiomyocytes.
Zinc Protects against Heat Stress-Induced Apoptosis via the Inhibition of Endoplasmic Reticulum Stress in TM3 Leydig Cells.
Exosomes released from Sertoli cells contribute to the survival of Leydig cells through CCL20 in rats.
VPA and TSA Interrupt the Interplay between mutp53 and HSP70, Leading to CHK1 and RAD51 Down-Regulation and Sensitizing Pancreatic Cancer Cells to AZD2461 PARP Inhibitor.
Hypoxia-Preconditioned Extracellular Vesicles from Mesenchymal Stem Cells Improve Cartilage Repair in Osteoarthritis.
Exosomes derived from M2 type tumor-associated macrophages promote osimertinib resistance in non-small cell lung cancer through MSTRG.292666.16-miR-6836-5p-MAPK8IP3 axis.
Regorafenib and reactive metabolite of sunitinib activate inflammasomes: Implications for multi tyrosine kinase inhibitor-Iiduced immune related adverse events.
Exosomes derived from human umbilical cord mesenchymal stem cells protect against papain-induced emphysema by preventing apoptosis through activating VEGF-VEGFR2-mediated AKT and MEK/ERK pathways in rats.
Anserine and Carnosine Induce HSP70-Dependent H(2)S Formation in Endothelial Cells and Murine Kidney.
Effect of miR-143-3p from Extracellular Vesicles of Porcine Uterine Luminal Fluid on Porcine Trophoblast Cells.
Effects of the probiotic, Lactobacillus rhamnosus GG, on ulcer pathogenesis, HSP70 stress protein and nitric oxide levels in stress induced ulcer.
Human breast milk-derived exosomes through inhibiting AT II cell apoptosis to prevent bronchopulmonary dysplasia in rat lung.
Jianpi Huayu decoction inhibits the epithelial-mesenchymal transition of hepatocellular carcinoma cells by suppressing exosomal miR-23a-3p/Smad signaling.
The alleviative effect of thyroid hormone on cold stress-induced apotosis via HSP70 and mitochondrial apoptosis signal pathway in bovine Sertoli cells.
Nicotinamide mononucleotide alleviates heat stress-induced oxidative stress and apoptosis in BMECs through reducing mitochondrial damage and endoplasmic reticulum stress.
Distinct Gene Expression Patterns of Two Heat Shock Protein 70 Members During Development, Diapause, and Temperature Stress in the Freshwater Crustacean Daphnia magna.
Exosomes Isolated From Bone Marrow Mesenchymal Stem Cells Exert a Protective Effect on Osteoarthritis via lncRNA LYRM4-AS1-GRPR-miR-6515-5p.
The Formation of Melanocyte Apoptotic Bodies in Vitiligo and the Relocation of Vitiligo Autoantigens under Oxidative Stress.
Long Noncoding RNA RP11-115N4.1 Promotes Inflammatory Responses by Interacting With HNRNPH3 and Enhancing the Transcription of HSP70 in Unexplained Recurrent Spontaneous Abortion.
LncRNA FOXP4-AS1 Promotes Progression of Ewing Sarcoma and Is Associated With Immune Infiltrates.
Exogenous H(2) S prevents the nuclear translocation of PDC-E1 and inhibits vascular smooth muscle cell proliferation in the diabetic state.
Regulating immune memory and reversing tumor thermotolerance through a step-by-step starving-photothermal therapy.
Differential Expression Pattern of Goat Uterine Fluids Extracellular Vesicles miRNAs during Peri-Implantation.
SIRT3 protects bovine mammary epithelial cells from heat stress damage by activating the AMPK signaling pathway.
Repair of peripheral nerve defects by nerve grafts incorporated with extracellular vesicles from skin-derived precursor Schwann cells.
Melatonin potentiates the cytotoxic effect of Neratinib in HER2(+) breast cancer through promoting endocytosis and lysosomal degradation of HER2.
GADD45β stabilized by direct interaction with HSP72 ameliorates insulin resistance and lipid accumulation.
Dendrobium officinale Polysaccharide Alleviates Intestinal Inflammation by Promoting Small Extracellular Vesicle Packaging of miR-433-3p.
Lipidomic Profiling of Human Milk Derived Exosomes and Their Emerging Roles in the Prevention of Necrotizing Enterocolitis.
Dihydromyricetin attenuates heat stress-induced apoptosis in dairy cow mammary epithelial cells through suppressing mitochondrial dysfunction.
Cardiomyocyte contractile impairment in heart failure results from reduced BAG3-mediated sarcomeric protein turnover.
Cytokine Profile in Plasma Extracellular Vesicles of Parkinson's Disease and the Association with Cognitive Function.
Hypoxic tumor-derived exosomal circular RNA SETDB1 promotes invasive growth and EMT via the miR-7/Sp1 axis in lung adenocarcinoma.
Osteosarcoma-derived exosomal miR-501-3p promotes osteoclastogenesis and aggravates bone loss.
UBQLN2-HSP70 axis reduces poly-Gly-Ala aggregates and alleviates behavioral defects in the C9ORF72 animal model.
Dual roles of HSP70 chaperone HSPA1 in quality control of nascent and newly synthesized proteins.
Seminal exosomal miR-210-3p as a potential marker of Sertoli cell damage in Varicocele.
The Role and Mechanism of Exosomes from Umbilical Cord Mesenchymal Stem Cells in Inducing Osteogenesis and Preventing Osteoporosis.
The EGFR-HSF1 axis accelerates the tumorigenesis of pancreatic cancer.
Hsp90 is involved in pseudorabies virus virion assembly via stabilizing major capsid protein VP5.
Spermine Protects Cardiomyocytes from High Glucose-Induced Energy Disturbance by Targeting the CaSR-gp78-Ubiquitin Proteasome System.
Boron Attenuates Heat Stress-Induced Apoptosis by Inhibiting Endoplasmic Reticulum Stress in Mouse Granulosa Cells.
Small extracellular vesicle-mediated Hsp70 intercellular delivery enhances breast cancer adriamycin resistance.
Exosomes secreted from mesenchymal stem cells mediate the regeneration of endothelial cells treated with rapamycin by delivering pro-angiogenic microRNAs.
SKP-SC-EVs Mitigate Denervated Muscle Atrophy by Inhibiting Oxidative Stress and Inflammation and Improving Microcirculation.
Exosomal miR-193b-5p as a regulator of LPS-induced inflammation in dairy cow mammary epithelial cells.
Augmentation of the heat shock axis during exceptional longevity in Ames dwarf mice.
Recovery from heat shock requires the microRNA pathway in Caenorhabditis elegans.
A novel Hsp70 inhibitor specifically targeting the cancer-related Hsp70-Bim protein-protein interaction.
Amiodarone, Unlike Dronedarone, Activates Inflammasomes via Its Reactive Metabolites: Implications for Amiodarone Adverse Reactions.
Tubocapsenolide A targets C-terminal cysteine residues of HSP90 to exert the anti-tumor effect.
Adipose-derived stem cell exosomes facilitate rotator cuff repair by mediating tendon-derived stem cells.
Construction of Smart Nanotheranostic Platform Bi-Ag@PVP: Multimodal CT/PA Imaging-Guided PDT/PTT for Cancer Therapy.
S-allyl cysteine ameliorates heat stress-induced oxidative stress by activating Nrf2/HO-1 signaling pathway in BMECs.
Hepatitis A virus structural protein pX interacts with ALIX and promotes the secretion of virions and foreign proteins through exosome-like vesicles.
TRIM16 Promotes Osteogenic Differentiation of Human Periodontal Ligament Stem Cells by Modulating CHIP-Mediated Degradation of RUNX2.
An Eight-CircRNA Assessment Model for Predicting Biochemical Recurrence in Prostate Cancer.
Reactive metabolite of gefitinib activates inflammasomes: implications for gefitinib-induced idiosyncratic reaction.
Ultraviolet B irradiation enhances the secretion of exosomes by human primary melanocytes and changes their exosomal miRNA profile.
Hsp90 inhibitor HSP990 in very low dose upregulates EAAT2 and exerts potent antiepileptic activity.
Extracellular vesicle-mediated delivery of miR-101 inhibits lung metastasis in osteosarcoma.
circFMN2 Sponges miR-1238 to Promote the Expression of LIM-Homeobox Gene 2 in Prostate Cancer Cells.
Multifactorial Attenuation of the Murine Heat Shock Response With Age.
UBE2T-regulated H2AX monoubiquitination induces hepatocellular carcinoma radioresistance by facilitating CHK1 activation.
CDK5RAP3, a Novel Nucleoplasmic Shuttle, Deeply Regulates HSF1-Mediated Heat Stress Response and Protects Mammary Epithelial Cells from Heat Injury.
Small extracellular vesicle-bound vascular endothelial growth factor secreted by carcinoma-associated fibroblasts promotes angiogenesis in a bevacizumab-resistant manner.
Exogenous spermine attenuates rat diabetic cardiomyopathy via suppressing ROS-p53 mediated downregulation of calcium-sensitive receptor.
Liver-derived exosome-laden lncRNA MT1DP aggravates cadmium-induced nephrotoxicity.
Light-activated oxygen self-supplied starving therapy in near-infrared (NIR) window and adjuvant hyperthermia-induced tumor ablation with an augmented sensitivity.
Heat Stress Impairs the Physiological Responses and Regulates Genes Coding for Extracellular Exosomal Proteins in Rat.
Exosomes carrying ALDOA and ALDH3A1 from irradiated lung cancer cells enhance migration and invasion of recipients by accelerating glycolysis.
Tumor-Derived EV-Encapsulated miR-181b-5p Induces Angiogenesis to Foster Tumorigenesis and Metastasis of ESCC.
Circulating Exosomes From Lipopolysaccharide-Induced Ards Mice Trigger Endoplasmic Reticulum Stress in Lung Tissue.
CaCBL1 Acts as a Positive Regulator in Pepper Response to Ralstonia solanacearum.
LASP1 promotes proliferation, metastasis, invasion in head and neck squamous cell carcinoma and through direct interaction with HSPA1A.
Selenium Attenuates Chronic Heat Stress-Induced Apoptosis via the Inhibition of Endoplasmic Reticulum Stress in Mouse Granulosa Cells.
Enterovirus A71 capsid protein VP1 increases blood-brain barrier permeability and virus receptor vimentin on the brain endothelial cells.
Extracellular Vesicles from Hyperammonemic Rats Induce Neuroinflammation and Motor Incoordination in Control Rats.
Hepatic DNAJB9 Drives Anabolic Biasing to Reduce Steatosis and Obesity.
Extracellular vesicles from skin precursor-derived Schwann cells promote axonal outgrowth and regeneration of motoneurons via Akt/mTOR/p70S6K pathway.
Heat stress activates YAP/TAZ to induce the heat shock transcriptome.
Antagomirs targeting miR-142-5p attenuate pilocarpine-induced status epilepticus in mice.
Heat stress induces apoptosis through disruption of dynamic mitochondrial networks in dairy cow mammary epithelial cells.
Rosmarinic acid exerts a neuroprotective effect on spinal cord injury by suppressing oxidative stress and inflammation via modulating the Nrf2/HO-1 and TLR4/NF-κB pathways.
Adipose-derived exosomes protect the pulmonary endothelial barrier in ventilator-induced lung injury by inhibiting the TRPV4/Ca(2+) signaling pathway.
Hypoxia preconditioned renal tubular epithelial cell-derived extracellular vesicles alleviate renal ischaemia-reperfusion injury mediated by the HIF-1α/Rab22 pathway and potentially affected by microRNAs.
(-)-Oleocanthal and (-)-oleocanthal-rich olive oils induce lysosomal membrane permeabilization in cancer cells.
The Capsid Protein VP1 of Coxsackievirus B Induces Cell Cycle Arrest by Up-Regulating Heat Shock Protein 70.
Mapping Interactome Networks of DNAJC11, a Novel Mitochondrial Protein Causing Neuromuscular Pathology in Mice.
Hepatitis B virus-regulated growth of liver cancer cells occurs through the microRNA-340-5p-activating transcription factor 7-heat shock protein A member 1B axis.
An acquired scaffolding function of the DNAJ-PKAc fusion contributes to oncogenic signaling in fibrolamellar carcinoma.
The circRNA circPTPRA suppresses epithelial-mesenchymal transitioning and metastasis of NSCLC cells by sponging miR-96-5p.
Bioinspired extracellular vesicles embedded with black phosphorus for molecular recognition-guided biomineralization.
Elevated levels of circulating ITIH4 are associated with hepatocellular carcinoma with nonalcoholic fatty liver disease: from pig model to human study.
The up-regulation of two identified wound healing specific proteins-HSP70 and lysozyme in regenerated Eisenia fetida through transcriptome analysis.
The exosome-like vesicles from osteoarthritic chondrocyte enhanced mature IL-1β production of macrophages and aggravated synovitis in osteoarthritis.
HMGB1-mediated differential response on hippocampal neurotransmitter disorder and neuroinflammation in adolescent male and female mice following cold exposure.
Exosomes from glioma cells induce a tumor-like phenotype in mesenchymal stem cells by activating glycolysis.
Design, synthesis and molecular mechanisms of novel dual inhibitors of heat shock protein 90/phosphoinositide 3-kinase alpha (Hsp90/PI3Kα) against cutaneous melanoma.
Necroptosis promotes autophagy-dependent upregulation of DAMP and results in immunosurveillance.
Inhibition of Heat Shock Protein 90 by 17-AAG Reduces Inflammation via P2X7 Receptor/NLRP3 Inflammasome Pathway and Increases Neurogenesis After Subarachnoid Hemorrhage in Mice.
Circulating exosomes contain protein biomarkers of metastatic non-small-cell lung cancer.
A proteomic approach reveals the differential protein expression in Drosophila melanogaster treated with red ginseng extract (Panax ginseng).
Curcumin inhibits liver cancer by inhibiting DAMP molecule HSP70 and TLR4 signaling.
Effects of Boron Supplementation on Expression of Hsp70 in the Spleen of African Ostrich.
Uncoupling of Metabolic Health from Longevity through Genetic Alteration of Adipose Tissue Lipid-Binding Proteins.
HSP90 recognizes the N-terminus of huntingtin involved in regulation of huntingtin aggregation by USP19.
Calcium sensing receptor protects high glucose-induced energy metabolism disorder via blocking gp78-ubiquitin proteasome pathway.
A comparative proteomic analysis reveals important proteins for the fertilization and early embryonic development of the oyster Crassostrea gigas.
Multifunctional WS(2) @Poly(ethylene imine) Nanoplatforms for Imaging Guided Gene-Photothermal Synergistic Therapy of Cancer.
Interferon α Induces the Apoptosis of Cervical Cancer HeLa Cells by Activating both the Intrinsic Mitochondrial Pathway and Endoplasmic Reticulum Stress-Induced Pathway.
Modification of the hTERT promoter by heat shock elements enhances the efficiency and specificity of cancer targeted gene therapy.
Changes in gene expression and content of Hsp70 and Hsp90 in striated muscles of mice after 30-day space flight on the biosatellite Bion-M1.
Identification of Hsf1 as a novel androgen receptor-regulated gene in mouse Sertoli cells.
Role of the nucleus tractus solitarii in the protection of pre-moxibustion on gastric mucosal lesions.
Effects of pre-moxibustion at Zusanli (ST36) on heat shock protein 70 expression in rats with gastric mucosal lesions after neurotomy.
Ji J, Cui MK, Zou R, Wu MZ, Ge MX, Li J, Zhang ZR
Molecular cell 2024 May 16;84(10):1917-1931.e15
Molecular cell 2024 May 16;84(10):1917-1931.e15
A combination of PD-L1-targeted IL-15 mRNA nanotherapy and ultrasound-targeted microbubble destruction for tumor immunotherapy.
Wang X, Li F, Zhang J, Guo L, Shang M, Sun X, Xiao S, Shi D, Meng D, Zhao Y, Jiang C, Li J
Journal of controlled release : official journal of the Controlled Release Society 2024 Mar;367:45-60
Journal of controlled release : official journal of the Controlled Release Society 2024 Mar;367:45-60
Selenomethionine alleviates chronic heat stress-induced breast muscle injury and poor meat quality in broilers via relieving mitochondrial dysfunction and endoplasmic reticulum stress.
Jing J, Wang J, Xiang X, Yin S, Tang J, Wang L, Jia G, Liu G, Chen X, Tian G, Cai J, Kang B, Che L, Zhao H
Animal nutrition (Zhongguo xu mu shou yi xue hui) 2024 Mar;16:363-375
Animal nutrition (Zhongguo xu mu shou yi xue hui) 2024 Mar;16:363-375
Bi(2)S(3)/Ti(3)C(2)-TPP nano-heterostructures induced by near-infrared for photodynamic therapy combined with photothermal therapy on hypoxic tumors.
Jiang H, Sun J, Liu F, Zhao Y, Chen X, Dai C, Wen Z
Journal of nanobiotechnology 2024 Mar 20;22(1):123
Journal of nanobiotechnology 2024 Mar 20;22(1):123
L-Theanine alleviates heat stress through modulation of gut microbiota and immunity.
Liu S, Wang B, Lin L, Xu W, Gong ZH, Xiao WJ
Journal of the science of food and agriculture 2024 Mar 15;104(4):2059-2072
Journal of the science of food and agriculture 2024 Mar 15;104(4):2059-2072
Plasma extracellular vesicle synaptic proteins as biomarkers of clinical progression in patients with Parkinson's disease.
Hong CT, Chung CC, Yu RC, Chan L
eLife 2024 Mar 14;12
eLife 2024 Mar 14;12
The mitochondrial UPR induced by ATF5 attenuates intervertebral disc degeneration via cooperating with mitophagy.
Xu WN, Zheng HL, Yang RZ, Sun YF, Peng BR, Liu C, Song J, Jiang SD, Zhu LX
Cell biology and toxicology 2024 Mar 13;40(1):16
Cell biology and toxicology 2024 Mar 13;40(1):16
Ponicidin-induced conformational changes of HSP90 regulates the MAPK pathway to relieve ulcerative colitis.
Zhang X, Xu Y, Fan M, Lv X, Long J, Yang R, Zhang R, Liu Z, Gu J, Wu P, Wang C
Journal of ethnopharmacology 2024 Mar 1;321:117483
Journal of ethnopharmacology 2024 Mar 1;321:117483
Reactive metabolite of trovafloxacin activates inflammasomes: Implications for trovafloxacin-induced liver injury.
Tanaka S, Noda T, Urashima K, Ijiri Y, Kohda Y, Kato R
Journal of applied toxicology : JAT 2024 Jun;44(6):846-852
Journal of applied toxicology : JAT 2024 Jun;44(6):846-852
Engineered Luminescent Oncolytic Vaccinia Virus Activation of Photodynamic-Immune Combination Therapy for Colorectal Cancer.
Ye LY, Li YS, Ge T, Liu LC, Si JX, Yang X, Fan WJ, Liu XZ, Zhang YN, Wang JW, Wang SB, Zou H, Zheng YL, Jin KT, Mao ZW, Cai Y, Mou XZ
Advanced healthcare materials 2024 Jul;13(17):e2304136
Advanced healthcare materials 2024 Jul;13(17):e2304136
Effects of spinal cord injury associated exosomes delivered tRF-41 on the progression of spinal cord injury progression.
Cai H, Zhang Y, Meng F, Li Y
Genomics 2024 Jul;116(4):110885
Genomics 2024 Jul;116(4):110885
Extracellular vesicles separated from goat milk by differential centrifugation coupled with sodium citrate pretreatments.
Fu S, Zhu L, Yang X, Jiao Y, Hao G, Liu Y
Food chemistry 2024 Jul 15;446:138807
Food chemistry 2024 Jul 15;446:138807
Ambra1 in exosomes secreted by HK-2 cells damaged by supersaturated oxalate induce mitophagy and autophagy-ferroptosis in normal HK-2 cells to participate in the occurrence of kidney stones.
Su X, Song C, He Z, Song Q, Meng L, Dong C, Zhou J, Ke H, Xiong Y, Liu J, Liao W, Yang S
Biochimica et biophysica acta. Molecular cell research 2024 Jan;1871(1):119604
Biochimica et biophysica acta. Molecular cell research 2024 Jan;1871(1):119604
Huc-MSC-derived exosomal miR-144 alleviates inflammation in LPS-induced preeclampsia-like pregnant rats via the FosB/Flt-1 pathway.
Sun J, Zhang W
Heliyon 2024 Jan 30;10(2):e24575
Heliyon 2024 Jan 30;10(2):e24575
Deep learning enables the discovery of a novel cuproptosis-inducing molecule for the inhibition of hepatocellular carcinoma.
Yang F, Jia L, Zhou HC, Huang JN, Hou MY, Liu FT, Prabhu N, Li ZJ, Yang CB, Zou C, Nordlund P, Wang JG, Dai LY
Acta pharmacologica Sinica 2024 Feb;45(2):391-404
Acta pharmacologica Sinica 2024 Feb;45(2):391-404
Differential Proteomic Profiles of Coronary Serum Exosomes in Acute Myocardial Infarction Patients with or Without Diabetes Mellitus: ANGPTL6 Accelerates Regeneration of Endothelial Cells Treated with Rapamycin via MAPK Pathways.
Wang W, Zhao Y, Zhu P, Jia X, Wang C, Zhang Q, Li H, Wang J, Hou Y
Cardiovascular drugs and therapy 2024 Feb;38(1):13-29
Cardiovascular drugs and therapy 2024 Feb;38(1):13-29
Disrupted HSF1 regulation in normal and exceptional brain aging.
Trivedi R, Knopf B, Rakoczy S, Manocha GD, Brown-Borg H, Jurivich DA
Biogerontology 2024 Feb;25(1):147-160
Biogerontology 2024 Feb;25(1):147-160
CircMTA2 Drives Gastric Cancer Progression through Suppressing MTA2 Degradation via Interacting with UCHL3.
Xie G, Lei B, Yin Z, Xu F, Liu X
International journal of molecular sciences 2024 Feb 29;25(5)
International journal of molecular sciences 2024 Feb 29;25(5)
Recruitment of BAG2 to DNAJ-PKAc scaffolds promotes cell survival and resistance to drug-induced apoptosis in fibrolamellar carcinoma.
Lauer SM, Omar MH, Golkowski MG, Kenerson HL, Lee KS, Pascual BC, Lim HC, Forbush K, Smith FD, Gordan JD, Ong SE, Yeung RS, Scott JD
Cell reports 2024 Feb 27;43(2):113678
Cell reports 2024 Feb 27;43(2):113678
Protein phosphatase 1 regulatory subunit 15 A promotes translation initiation and induces G2M phase arrest during cuproptosis in cancers.
Liu C, Chen L, Cong Y, Cheng L, Shuai Y, Lv F, Chen K, Song Y, Xing Y
Cell death & disease 2024 Feb 16;15(2):149
Cell death & disease 2024 Feb 16;15(2):149
Data on mitochondrial respiratory function in skeletal muscle of adult male mice in response to 3-weeks heat stress.
Koma R, Matsumoto T, Yamazaki A, Shibaguchi T, Jue T, Masuda K
Data in brief 2024 Apr;53:110091
Data in brief 2024 Apr;53:110091
Dual RNA sequencing of Helicobacter pylori and host cell transcriptomes reveals ontologically distinct host-pathogen interaction.
Hu W, Zhai ZY, Huang ZY, Chen ZM, Zhou P, Li XX, Yang GH, Bao CJ, You LJ, Cui XB, Xia GL, Ou Yang MP, Zhang L, Wu WKK, Li LF, Zhang YX, Xiao ZG, Gong W
mSystems 2024 Apr 16;9(4):e0020624
mSystems 2024 Apr 16;9(4):e0020624
Quantitative Measurement of Transthyretin Mistargeting by Proximity Labeling and Parallel Reaction Monitoring.
Lyu Z, Genereux JC
Frontiers in chemical biology 2023;2
Frontiers in chemical biology 2023;2
Cuproptosis enhances docetaxel chemosensitivity by inhibiting autophagy via the DLAT/mTOR pathway in prostate cancer.
Wen H, Qu C, Wang Z, Gao H, Liu W, Wang H, Sun H, Gu J, Yang Z, Wang X
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2023 Sep;37(9):e23145
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2023 Sep;37(9):e23145
Exploiting immunostimulatory mechanisms of immunogenic cell death to develop membrane-encapsulated nanoparticles as a potent tumor vaccine.
Liu Q, Hu Y, Zheng P, Yang Y, Fu Y, Yang Y, Duan B, Wang M, Li D, Li W, He J, Zheng X, Long Q, Ma Y
Journal of nanobiotechnology 2023 Sep 8;21(1):326
Journal of nanobiotechnology 2023 Sep 8;21(1):326
Fluorescence Tracking of Small Extracellular Vesicles In Vivo.
Chen Y, Shi Y, Tao Z
Pharmaceutics 2023 Sep 8;15(9)
Pharmaceutics 2023 Sep 8;15(9)
Quantitative proteomic analysis of local and systemic extracellular vesicles during Eimeria falciformis infectious cycle in the host.
Olajide JS, Qu Z, Yang S, Yang B, Xu X, Wang J, Cai J
Parasites & vectors 2023 Sep 27;16(1):339
Parasites & vectors 2023 Sep 27;16(1):339
USP14 Positively Modulates Head and Neck Squamous Carcinoma Tumorigenesis and Potentiates Heat Shock Pathway through HSF1 Stabilization.
Wang J, Xiang Y, Xie Z, Fan M, Fang S, Wan H, Zhao R, Zeng F, Hua Q
Cancers 2023 Sep 1;15(17)
Cancers 2023 Sep 1;15(17)
Evaluation the role of cuproptosis-related genes in the pathogenesis, diagnosis and molecular subtypes identification of atherosclerosis.
Wang M, Cheng L, Xiang Q, Gao Z, Ding Y, Xie H, Chen X, Yu P, Shen L
Heliyon 2023 Oct;9(10):e21158
Heliyon 2023 Oct;9(10):e21158
Changes in the components of salivary exosomes due to initial periodontal therapy.
Yamaguchi A, Tsuruya Y, Igarashi K, Jin Z, Yamazaki-Takai M, Takai H, Nakayama Y, Ogata Y
Journal of periodontal & implant science 2023 Oct;53(5):347-361
Journal of periodontal & implant science 2023 Oct;53(5):347-361
Targeting TNFAIP2 induces immunogenic cell death and sensitizes glioblastoma multiforme to anti-PD-1 therapy.
Hou C, Shi S, Gao M, Ji J, Ma C, Wang T, Chen T, Liu Y, Zhong J, Zheng Y, Ye J, Ke Y
Journal of neuro-oncology 2023 Oct;165(1):79-90
Journal of neuro-oncology 2023 Oct;165(1):79-90
Phenyl dialkynylcarbinols, a Bioinspired Series of Synthetic Antitumor Acetylenic Lipids.
Bossuat M, Rullière P, Preuilh N, Peixoto A, Joly E, Gomez JG, Bourkhis M, Rodriguez F, Gonçalves F, Fabing I, Gaspard H, Bernardes-Génisson V, Maraval V, Ballereau S, Chauvin R, Britton S, Génisson Y
Journal of medicinal chemistry 2023 Oct 26;66(20):13918-13945
Journal of medicinal chemistry 2023 Oct 26;66(20):13918-13945
Tumor-repopulating cell-derived microparticles elicit cascade amplification of chemotherapy-induced antitumor immunity to boost anti-PD-1 therapy.
Bie N, Yong T, Wei Z, Liang Q, Zhang X, Li S, Li X, Li J, Gan L, Yang X
Signal transduction and targeted therapy 2023 Oct 25;8(1):408
Signal transduction and targeted therapy 2023 Oct 25;8(1):408
Effective myocardial infarction treatment by targeted accumulation of Sulforaphane using porous magnetic silica nanoparticles.
Zhang J, Dong Y, Liu X, Jin H, Wang S, An N, Wang L
International journal of pharmaceutics 2023 Oct 15;645:123389
International journal of pharmaceutics 2023 Oct 15;645:123389
M2 macrophage exosomal LINC01001 promotes non-small cell lung cancer development by affecting METTL3 and glycolysis pathway.
Xu L, Li K, Li J, Xu F, Liang S, Kong Y, Chen B
Cancer gene therapy 2023 Nov;30(11):1569-1580
Cancer gene therapy 2023 Nov;30(11):1569-1580
Nuclear import carrier Hikeshi cooperates with HSP70 to promote murine oligodendrocyte differentiation and CNS myelination.
Li L, Li D, Sun D, Zhang X, Lei W, Wu M, Huang Q, Nian X, Dai W, Lu X, Zhou Z, Zhu Y, Xiao Y, Zhang L, Mo W, Liu Z, Zhang L
Developmental cell 2023 Nov 6;58(21):2275-2291.e6
Developmental cell 2023 Nov 6;58(21):2275-2291.e6
The proteomics analysis of extracellular vesicles revealed the possible function of heat shock protein 60 in Helicobacter pylori infection.
Li Y, Cao H, Qiu D, Wang N, Wang Y, Wen T, Wang J, Zhu H
Cancer cell international 2023 Nov 16;23(1):272
Cancer cell international 2023 Nov 16;23(1):272
The HDAC inhibitor HFY-4A improves TUSC2 transcription to induce immunogenic cell death in breast cancer.
Yin Y, Guan X, Li G, Chen C, Duan Y, Yu Z
Toxicology and applied pharmacology 2023 Nov 1;478:116698
Toxicology and applied pharmacology 2023 Nov 1;478:116698
Pre-Induced ICD Membrane-Coated Carrier-Free Nanoparticles for the Personalized Lung Cancer Immunotherapy.
Li S, Jiang S, Rahman MSU, Mei J, Wang X, Jiang J, Chen Y, Xu S, Liu Y
Small methods 2023 May;7(5):e2201569
Small methods 2023 May;7(5):e2201569
SIRT2 regulates extracellular vesicle-mediated liver-bone communication.
Lin L, Guo Z, He E, Long X, Wang D, Zhang Y, Guo W, Wei Q, He W, Wu W, Li J, Wo L, Hong D, Zheng J, He M, Zhao Q
Nature metabolism 2023 May;5(5):821-841
Nature metabolism 2023 May;5(5):821-841
miR-27a-3p relieves heat stress-induced mitochondrial damage and aberrant milk protein synthesis through MEK/ERK pathway in BMECs.
Wang Y, Wu J, Xia SW, Zhao F, Ding Q, Ye XM, Zhong JF, Chen KL, Wang HL
Cell stress & chaperones 2023 May;28(3):265-274
Cell stress & chaperones 2023 May;28(3):265-274
Bone mesenchymal stem cell-derived exosomes involved co-delivery and synergism effect with icariin via mussel-inspired multifunctional hydrogel for cartilage protection.
Zeng J, Sun P, Zhao Y, Fang X, Wu Z, Qi X
Asian journal of pharmaceutical sciences 2023 May;18(3):100799
Asian journal of pharmaceutical sciences 2023 May;18(3):100799
Viral subversion of selective autophagy is critical for biogenesis of virus replication organelles.
Lan Y, van Leur SW, Fernando JA, Wong HH, Kampmann M, Siu L, Zhang J, Li M, Nicholls JM, Sanyal S
Nature communications 2023 May 10;14(1):2698
Nature communications 2023 May 10;14(1):2698
Exosomes from tubular epithelial cells undergoing epithelial-to-mesenchymal transition promote renal fibrosis by M1 macrophage activation.
Lu Y, Zhang R, Gu X, Wang X, Xi P, Chen X
FASEB bioAdvances 2023 Mar;5(3):101-113
FASEB bioAdvances 2023 Mar;5(3):101-113
HSPA1A ameliorated spinal cord injury in rats by inhibiting apoptosis to exert neuroprotective effects.
He X, Guo X, Deng B, Kang J, Liu W, Zhang G, Wang Y, Yang Y, Kang X
Experimental neurology 2023 Mar;361:114301
Experimental neurology 2023 Mar;361:114301
Taxol‑resistant breast cancer cell‑derived exosome‑delivered miR‑187‑5p regulates the growth of breast cancer cells via ABCD2 and Wnt/β‑catenin signaling.
Wu T, Zhu D, Wu X, Zhang N, Zhang Q
Oncology letters 2023 Mar;25(3):119
Oncology letters 2023 Mar;25(3):119
PTEN Deficiency Facilitates Exosome Secretion and Metastasis in Cholangiocarcinoma by Impairing TFEB-mediated Lysosome Biogenesis.
Jiang TY, Shi YY, Cui XW, Pan YF, Lin YK, Feng XF, Ding ZW, Yang C, Tan YX, Dong LW, Wang HY
Gastroenterology 2023 Mar;164(3):424-438
Gastroenterology 2023 Mar;164(3):424-438
A curcumin analogue GO-Y030 depletes cancer stem cells by inhibiting the interaction between the HSP70/HSP40 complex and its substrates.
Suzuki M, Yamamoto Y, Nishijima-Matsunobu A, Kawasaki Y, Shibata H, Omori Y
FEBS open bio 2023 Mar;13(3):434-446
FEBS open bio 2023 Mar;13(3):434-446
Cytokine profiles of plasma extracellular vesicles as progression biomarkers in Parkinson's disease.
Chan L, Chung CC, Yu RC, Hong CT
Aging 2023 Mar 9;15(5):1603-1614
Aging 2023 Mar 9;15(5):1603-1614
Extracellular vesicles from Zika virus-infected cells display viral E protein that binds ZIKV-neutralizing antibodies to prevent infection enhancement.
Zhao F, Xu Y, Liu N, Lv D, Chen Y, Liu Z, Jin X, Xiao M, Lavillette D, Zhong J, Bartenschlager R, Long G
The EMBO journal 2023 Mar 15;42(6):e112096
The EMBO journal 2023 Mar 15;42(6):e112096
Near-Infrared Phototheranostic Iron Pyrite Nanocrystals Simultaneously Induce Dual Cell Death Pathways via Enhanced Fenton Reactions in Triple-Negative Breast Cancer.
Zhao C, Liu Z, Chang CC, Chen YC, Zhang Q, Zhang XD, Andreou C, Pang J, Liu ZX, Wang DY, Kircher MF, Yang J
ACS nano 2023 Mar 14;17(5):4261-4278
ACS nano 2023 Mar 14;17(5):4261-4278
A cytosolic surveillance mechanism activates the mitochondrial UPR.
Sutandy FXR, Gößner I, Tascher G, Münch C
Nature 2023 Jun;618(7966):849-854
Nature 2023 Jun;618(7966):849-854
Recruitment of BAG2 to DNAJ-PKAc scaffolds promotes cell survival and resistance to drug-induced apoptosis in fibrolamellar carcinoma.
Lauer SM, Omar MH, Golkowski MG, Kenerson HL, Pascual BC, Forbush K, Smith FD, Gordan J, Ong SE, Yeung RS, Scott JD
bioRxiv : the preprint server for biology 2023 Jun 28;
bioRxiv : the preprint server for biology 2023 Jun 28;
Albumosomes formed by cytoplasmic pre-folding albumin maintain mitochondrial homeostasis and inhibit nonalcoholic fatty liver disease.
Ma B, Ju A, Zhang S, An Q, Xu S, Liu J, Yu L, Fu Y, Luo Y
Signal transduction and targeted therapy 2023 Jun 16;8(1):229
Signal transduction and targeted therapy 2023 Jun 16;8(1):229
Dextran 40 hybrid biomimetic bismuth-nanoflower designed for NIR II-triggered hypoxic tumor thermoradiotherapy via macrophage escape.
Wen J, Liu C, Liu J, Wang L, Miao S, Chen D, Wang Q, Huo M, Shen Y
Carbohydrate polymers 2023 Jun 15;310:120697
Carbohydrate polymers 2023 Jun 15;310:120697
Carnosinase-1 Knock-Out Reduces Kidney Fibrosis in Type-1 Diabetic Mice on High Fat Diet.
Pfeffer T, Wetzel C, Kirschner P, Bartosova M, Poth T, Schwab C, Poschet G, Zemva J, Bulkescher R, Damgov I, Thiel C, Garbade SF, Klingbeil K, Peters V, Schmitt CP
Antioxidants (Basel, Switzerland) 2023 Jun 14;12(6)
Antioxidants (Basel, Switzerland) 2023 Jun 14;12(6)
Long noncoding RNA HITT coordinates with RGS2 to inhibit PD-L1 translation in T cell immunity.
Lin Q, Liu T, Wang X, Hou G, Xiang Z, Zhang W, Zheng S, Zhao D, Leng Q, Zhang X, Lu M, Guan T, Liu H, Hu Y
The Journal of clinical investigation 2023 Jun 1;133(11)
The Journal of clinical investigation 2023 Jun 1;133(11)
Control of SOX2 protein stability and tumorigenic activity by E3 ligase CHIP in esophageal cancer cells.
Kang L, Zhang H, Wang Y, Chu M, He J, Xue M, Pan L, Zhang Y, Wang Z, Chen Z, Huang Y, Chen Z, Li E, Li J, Xu L, Zhang R, Wong J
Oncogene 2023 Jul;42(30):2315-2328
Oncogene 2023 Jul;42(30):2315-2328
Combination therapy with BMSCs‑exosomes and porous tantalum for the repair of femur supracondylar defects.
Yang F, Wu M, Chen H, Ma S, Liu J, Li C, Li Y, Yang J, Liu B, Zhao D
Molecular medicine reports 2023 Jul;28(1)
Molecular medicine reports 2023 Jul;28(1)
Roles of hypoxic environment and M2 macrophage-derived extracellular vesicles on the progression of non-small cell lung cancer.
Chu X, Wang Z, Wang W, Liu W, Cao Y, Feng L
BMC pulmonary medicine 2023 Jul 3;23(1):239
BMC pulmonary medicine 2023 Jul 3;23(1):239
Cellular Exposure to Chloroacetanilide Herbicides Induces Distinct Protein Destabilization Profiles.
Quanrud GM, Lyu Z, Balamurugan SV, Canizal C, Wu HT, Genereux JC
ACS chemical biology 2023 Jul 21;18(7):1661-1676
ACS chemical biology 2023 Jul 21;18(7):1661-1676
Quantitative Measurement of Secretory Protein Mistargeting by Proximity Labeling and Parallel Reaction Monitoring.
Lyu Z, Genereux JC
bioRxiv : the preprint server for biology 2023 Jul 20;
bioRxiv : the preprint server for biology 2023 Jul 20;
Lysine butyrylation of HSP90 regulated by KAT8 and HDAC11 confers chemoresistance.
He Y, Zheng CC, Yang J, Li SJ, Xu TY, Wei X, Chen WY, Jiang ZL, Xu JJ, Zhang GG, Cheng C, Chen KS, Shi XY, Qin DJ, Liu JB, Li B
Cell discovery 2023 Jul 18;9(1):74
Cell discovery 2023 Jul 18;9(1):74
Cardiac myofibrillogenesis is spatiotemporally modulated by the molecular chaperone UNC45B.
Lu SH, Wu YH, Su LY, Hsu ZT, Weng TH, Wang HY, Yu C, Hsu PW, Tsai SY
Stem cell reports 2023 Jul 11;18(7):1405-1420
Stem cell reports 2023 Jul 11;18(7):1405-1420
Extracellular vesicles from mesenchymal stem cells reduce neuroinflammation in hippocampus and restore cognitive function in hyperammonemic rats.
Izquierdo-Altarejos P, Cabrera-Pastor A, Martínez-García M, Sánchez-Huertas C, Hernández A, Moreno-Manzano V, Felipo V
Journal of neuroinflammation 2023 Jan 2;20(1):1
Journal of neuroinflammation 2023 Jan 2;20(1):1
Exosomal microRNAs regulate the heat stress response in sea cucumber Apostichopus japonicus.
Huo D, Su F, Yang H, Sun L
Ecotoxicology and environmental safety 2023 Jan 1;249:114419
Ecotoxicology and environmental safety 2023 Jan 1;249:114419
iASPP suppression mediates terminal UPR and improves BRAF-inhibitor sensitivity of colon cancers.
Zheng S, Wang X, Liu H, Zhao D, Lin Q, Jiang Q, Li L, Hu Y
Cell death and differentiation 2023 Feb;30(2):327-340
Cell death and differentiation 2023 Feb;30(2):327-340
Hypoxia aggravates the burden of yellowstripe goby (Mugilogobius chulae) under atorvastatin exposure.
Wang Y, Tang T, Ren J, Zhao Y, Hou Y, Nie X
Aquatic toxicology (Amsterdam, Netherlands) 2023 Feb;255:106381
Aquatic toxicology (Amsterdam, Netherlands) 2023 Feb;255:106381
lncRNA SND1-IT1 delivered via intracerebral hemorrhage-derived exosomes affect the growth of human microglia by regulating the miR-124-3p/MTF1 axis.
Wang J, Teng F, Liu S, Pan X, Yang B, Wu W
Journal of cellular physiology 2023 Feb;238(2):366-378
Journal of cellular physiology 2023 Feb;238(2):366-378
Exosomes Derived from AT2R-Overexpressing BMSC Prevent Restenosis After Carotid Artery Injury by Attenuating the Injury-Induced Neointimal Hyperplasia.
Zou X, Liao Y, Liu Z, Xu X, Sun W, Qin H, Wang H, Liu J, Jing T
Journal of cardiovascular translational research 2023 Feb;16(1):112-126
Journal of cardiovascular translational research 2023 Feb;16(1):112-126
Distinctive chaperonopathy in skeletal muscle associated with the dominant variant in DNAJB4.
Inoue M, Noguchi S, Inoue YU, Iida A, Ogawa M, Bengoechea R, Pittman SK, Hayashi S, Watanabe K, Hosoi Y, Sano T, Takao M, Oya Y, Takahashi Y, Miyajima H, Weihl CC, Inoue T, Nishino I
Acta neuropathologica 2023 Feb;145(2):235-255
Acta neuropathologica 2023 Feb;145(2):235-255
Sex-Inclined Piwi-Interacting RNAs in Serum Exosomes for Sex Determination in the Greater Amberjack (Seriola dumerili).
Deng Q, Zhao N, Ru X, Hao R, Zhang B, Zhu C
International journal of molecular sciences 2023 Feb 8;24(4)
International journal of molecular sciences 2023 Feb 8;24(4)
Negatively charged bladder acellular matrix loaded with positively charged adipose-derived mesenchymal stem cell-derived small extracellular vesicles for bladder tissue engineering.
Yang T, Zhao F, Zhao J, Geng J, Shao C, Liu J, Sheng F, Zhou L, Xu H, Jia R
Journal of controlled release : official journal of the Controlled Release Society 2023 Dec;364:718-733
Journal of controlled release : official journal of the Controlled Release Society 2023 Dec;364:718-733
Tryptophan alleviates intestinal damage through regulating necroptosis and TLR4/NOD signaling pathways in pigs after lipopolysaccharide challenge.
Tao J, Liu G, Gu K, Jia G, Zhao H, Chen X, Tian G, Cai J, Wang J
Animal biotechnology 2023 Dec;34(9):4938-4946
Animal biotechnology 2023 Dec;34(9):4938-4946
Tryptophan alleviates lipopolysaccharide-induced liver injury and inflammation by modulating necroptosis and pyroptosis signaling pathways in piglets.
Gu K, Wang F, Sun W, Liu G, Jia G, Zhao H, Chen X, Wu C, Tian G, Cai J, Zhang R, Wang J
Animal biotechnology 2023 Dec;34(8):4069-4080
Animal biotechnology 2023 Dec;34(8):4069-4080
MiR-223-3p overexpressed adipose mesenchymal stem cell-derived exosomes promote wound healing via targeting MAPK10.
Liu X, Jin S, Liu J, Xu X
Acta histochemica 2023 Dec;125(8):152102
Acta histochemica 2023 Dec;125(8):152102
Caspase-9 inhibition triggers Hsp90-based chemotherapy-mediated tumor intrinsic innate sensing and enhances antitumor immunity.
Li J, Han X, Sun M, Li W, Yang G, Chen H, Guo B, Li J, Li X, Wang H
Journal for immunotherapy of cancer 2023 Dec 6;11(12)
Journal for immunotherapy of cancer 2023 Dec 6;11(12)
Betaine ameliorates heat stress-induced apoptosis by affecting oxidative and endoplasmic reticulum stress in mouse Leydig cells.
Xiong Y, Li B, Wang K, Li J, He S
Bioscience, biotechnology, and biochemistry 2023 Dec 19;88(1):53-62
Bioscience, biotechnology, and biochemistry 2023 Dec 19;88(1):53-62
Dysregulated Autophagy and Sarcomere Dysfunction in Patients With Heart Failure With Co-Occurrence of P63A and P380S BAG3 Variants.
Martin TG, Pak H, Gerhard GS, Merali S, Merali C, Lemster B, Dubey P, McTiernan CF, Bristow MR, Feldman AM, Kirk JA
Journal of the American Heart Association 2023 Dec 19;12(24):e029938
Journal of the American Heart Association 2023 Dec 19;12(24):e029938
Integrated bioinformatics and experiment revealed that cuproptosis is the potential common pathogenesis of three kinds of primary cardiomyopathy.
Wang M, Xu X, Li J, Gao Z, Ding Y, Chen X, Xiang Q, Shen L
Aging 2023 Dec 11;15(23):14210-14241
Aging 2023 Dec 11;15(23):14210-14241
Mechanism of non-steroidal anti-androgen-induced liver injury: Reactive metabolites of flutamide and bicalutamide activate inflammasomes.
Kato R, Yamada T, Noda T, Tanaka S, Kohda Y, Ijiri Y
Toxicology in vitro : an international journal published in association with BIBRA 2023 Aug;90:105606
Toxicology in vitro : an international journal published in association with BIBRA 2023 Aug;90:105606
Exosomal PGAM1 promotes prostate cancer angiogenesis and metastasis by interacting with ACTG1.
Luo JQ, Yang TW, Wu J, Lai HH, Zou LB, Chen WB, Zhou XM, Lv DJ, Cen SR, Long ZN, Mao YY, Zheng PX, Su XH, Xian ZY, Shu FP, Mao XM
Cell death & disease 2023 Aug 4;14(8):502
Cell death & disease 2023 Aug 4;14(8):502
Tumor-Associated Extracellular Microvesicles with Fluorine-Modified Carbohydrate Antigens Trigger a Stronger Antitumor Immune Response.
Mo J, Zou Y, Li BH, Li G, Zheng XJ, Liu Y, Ye XS
ACS applied materials & interfaces 2023 Aug 30;15(34):40201-40212
ACS applied materials & interfaces 2023 Aug 30;15(34):40201-40212
Effects of diazoxide on streptozotocin induced β cell damage via HSP70/HSP90/TLR4/AMPK signaling pathways.
Kaya ST
Biotechnic & histochemistry : official publication of the Biological Stain Commission 2023 Apr;98(3):210-219
Biotechnic & histochemistry : official publication of the Biological Stain Commission 2023 Apr;98(3):210-219
Degradation of neurodegenerative disease-associated TDP-43 aggregates and oligomers via a proteolysis-targeting chimera.
Tseng YL, Lu PC, Lee CC, He RY, Huang YA, Tseng YC, Cheng TR, Huang JJ, Fang JM
Journal of biomedical science 2023 Apr 26;30(1):27
Journal of biomedical science 2023 Apr 26;30(1):27
Differentially Expressed microRNAs in Peritoneal Dialysis Effluent-Derived Exosomes from the Patients with Ultrafiltration Failure.
Wu W, Wu X, Cheng Z, Yang Z, Lu M, Cheng J
Genetics research 2022;2022:2276175
Genetics research 2022;2022:2276175
Antimicrobial Effect of Extracellular Vesicles Derived From Human Oral Mucosal Epithelial Cells on Candida albicans.
Zhao M, Zhang M, Xu K, Wu K, Xie R, Li R, Wang Q, Liu W, Wang W, Wang X
Frontiers in immunology 2022;13:777613
Frontiers in immunology 2022;13:777613
Exosome-transmitted miR-3124-5p promotes cholangiocarcinoma development via targeting GDF11.
Gao H, He Z, Gao C, Liu N, Zhang Z, Niu W, Niu J, Peng C
Frontiers in oncology 2022;12:936507
Frontiers in oncology 2022;12:936507
PINK1-Dependent Mitophagy Reduced Endothelial Hyperpermeability and Cell Migration Capacity Under Simulated Microgravity.
Li C, Pan Y, Tan Y, Wang Y, Sun X
Frontiers in cell and developmental biology 2022;10:896014
Frontiers in cell and developmental biology 2022;10:896014
HucMSC-Ex carrying miR-203a-3p.2 ameliorates colitis through the suppression of caspase11/4-induced macrophage pyroptosis.
Xu Y, Tang X, Fang A, Yan J, Kofi Wiredu Ocansey D, Zhang X, Mao F
International immunopharmacology 2022 Sep;110:108925
International immunopharmacology 2022 Sep;110:108925
Depletion of serum-derived exosomes aggravates heat stress-induced damage of bovine mammary epithelial cells.
Wang Y, Wang HL, Lin ZP, Zhong JF, Chen KL, Duan X
Molecular biology reports 2022 Oct;49(10):9297-9305
Molecular biology reports 2022 Oct;49(10):9297-9305
c-Myc Sustains Pancreatic Cancer Cell Survival and mutp53 Stability through the Mevalonate Pathway.
Romeo MA, Gilardini Montani MS, Arena A, Benedetti R, D'Orazi G, Cirone M
Biomedicines 2022 Oct 5;10(10)
Biomedicines 2022 Oct 5;10(10)
Integrated Analysis of Transcriptome and microRNA Profile Reveals the Toxicity of Euphorbia Factors toward Human Colon Adenocarcinoma Cell Line Caco-2.
Zou L, Bao W, Gao Y, Chen M, Wu Y, Wang S, Li C, Zhang J, Zhang D, Wang Q, Zhu A
Molecules (Basel, Switzerland) 2022 Oct 16;27(20)
Molecules (Basel, Switzerland) 2022 Oct 16;27(20)
Defective Human SRP Induces Protein Quality Control and Triggers Stress Response.
Tikhonova EB, Gutierrez Guarnizo SA, Kellogg MK, Karamyshev A, Dozmorov IM, Karamysheva ZN, Karamyshev AL
Journal of molecular biology 2022 Nov 30;434(22):167832
Journal of molecular biology 2022 Nov 30;434(22):167832
Activation of the Chemokine Receptor CCR1 and Preferential Recruitment of Gαi Suppress RSV Replication: Implications for Developing Novel Respiratory Syncytial Virus Treatment Strategies.
Li J, Xue L, Wang J, Meng A, Qiao J, Li M, Wang X, Meng L, Ning J, Gao X, Li W, Ma C, Wei L
Journal of virology 2022 Nov 23;96(22):e0130922
Journal of virology 2022 Nov 23;96(22):e0130922
Design, synthesis, and biological evaluation of novel dual inhibitors of heat shock protein 90/mammalian target of rapamycin (Hsp90/mTOR) against bladder cancer cells.
Pan Z, Chen Y, Pang H, Wang X, Zhang Y, Xie X, He G
European journal of medicinal chemistry 2022 Nov 15;242:114674
European journal of medicinal chemistry 2022 Nov 15;242:114674
Exosome-derived FGD5-AS1 promotes tumor-associated macrophage M2 polarization-mediated pancreatic cancer cell proliferation and metastasis.
He Z, Wang J, Zhu C, Xu J, Chen P, Jiang X, Chen Y, Jiang J, Sun C
Cancer letters 2022 Nov 1;548:215751
Cancer letters 2022 Nov 1;548:215751
SIRT4 Expression Ameliorates the Detrimental Effect of Heat Stress via AMPK/mTOR Signaling Pathway in BMECs.
Ding Q, Wang Y, Xia SW, Zhao F, Zhong JF, Wang HL, Chen KL
International journal of molecular sciences 2022 Nov 1;23(21)
International journal of molecular sciences 2022 Nov 1;23(21)
BAG3 protects chondrocytes against lumbar facet joint osteoarthritis by regulating autophagy and apoptosis.
Lu X, Zhang J, Xue P, Wang Q, Wang X, Sun Y, Cui Z
Journal of physiology and biochemistry 2022 May;78(2):427-437
Journal of physiology and biochemistry 2022 May;78(2):427-437
Class 3 phosphoinositide 3-kinase promotes hepatic glucocorticoid receptor stability and transcriptional activity.
Shibayama Y, Alkhoury C, Nemazanyy I, F Henneman N, Cagnard N, Girard M, Atsumi T, Panasyuk G
Acta physiologica (Oxford, England) 2022 May;235(1):e13793
Acta physiologica (Oxford, England) 2022 May;235(1):e13793
Triptolide promotes degradation of the unfolded gain-of-function Tp53(R175H/Y220C) mutant protein by initiating heat shock protein 70 transcription in non-small cell lung cancer.
Zhou J, Luo J, Li P, Zhou Y, Li P, Wang F, Mallio CA, Rossi G, Jalal AH, Filipovic N, Tian Z, Zhao X
Translational lung cancer research 2022 May;11(5):802-816
Translational lung cancer research 2022 May;11(5):802-816
Inhibition of the CDK2 and Cyclin A complex leads to autophagic degradation of CDK2 in cancer cells.
Zhang J, Gan Y, Li H, Yin J, He X, Lin L, Xu S, Fang Z, Kim BW, Gao L, Ding L, Zhang E, Ma X, Li J, Li L, Xu Y, Horne D, Xu R, Yu H, Gu Y, Huang W
Nature communications 2022 May 20;13(1):2835
Nature communications 2022 May 20;13(1):2835
Engineered exosome as targeted lncRNA MEG3 delivery vehicles for osteosarcoma therapy.
Huang X, Wu W, Jing D, Yang L, Guo H, Wang L, Zhang W, Pu F, Shao Z
Journal of controlled release : official journal of the Controlled Release Society 2022 Mar;343:107-117
Journal of controlled release : official journal of the Controlled Release Society 2022 Mar;343:107-117
In situ injectable hydrogel-loaded drugs induce anti-tumor immune responses in melanoma immunochemotherapy.
Li J, Luo G, Zhang C, Long S, Guo L, Yang G, Wang F, Zhang L, Shi L, Fu Y, Zhang Y
Materials today. Bio 2022 Mar;14:100238
Materials today. Bio 2022 Mar;14:100238
LONP1-mediated mitochondrial quality control safeguards metabolic shifts in heart development.
Zhao K, Huang X, Zhao W, Lu B, Yang Z
Development (Cambridge, England) 2022 Mar 15;149(6)
Development (Cambridge, England) 2022 Mar 15;149(6)
SUMO2-mediated SUMOylation of SH3GLB1 promotes ionizing radiation-induced hypertrophic cardiomyopathy through mitophagy activation.
Gao A, Zou J, Mao Z, Zhou H, Zeng G
European journal of pharmacology 2022 Jun 5;924:174980
European journal of pharmacology 2022 Jun 5;924:174980
CircEZH2/miR-133b/IGF2BP2 aggravates colorectal cancer progression via enhancing the stability of m(6)A-modified CREB1 mRNA.
Yao B, Zhang Q, Yang Z, An F, Nie H, Wang H, Yang C, Sun J, Chen K, Zhou J, Bai B, Gu S, Zhao W, Zhan Q
Molecular cancer 2022 Jun 30;21(1):140
Molecular cancer 2022 Jun 30;21(1):140
Exosomal tRF-Leu-AAG-001 derived from mast cell as a potential non-invasive diagnostic biomarker for endometriosis.
Li Y, Cui S, Xu Z, Zhang Y, Wu T, Zhang J, Chen Y
BMC women's health 2022 Jun 25;22(1):253
BMC women's health 2022 Jun 25;22(1):253
Comparative transcriptome and Lipidome analyses suggest a lipid droplet-specific response to heat exposure of brown adipose tissue in normal and obese mice.
Wang Q, Liu Y, Xu Y, Jin Y, Wu J, Ren Z
Life sciences 2022 Jun 15;299:120540
Life sciences 2022 Jun 15;299:120540
Single-cell analysis of human basal cell carcinoma reveals novel regulators of tumor growth and the tumor microenvironment.
Guerrero-Juarez CF, Lee GH, Liu Y, Wang S, Karikomi M, Sha Y, Chow RY, Nguyen TTL, Iglesias VS, Aasi S, Drummond ML, Nie Q, Sarin K, Atwood SX
Science advances 2022 Jun 10;8(23):eabm7981
Science advances 2022 Jun 10;8(23):eabm7981
Targeted Analysis of HSP70 Isoforms in Human Spermatozoa in the Context of Capacitation and Motility.
Grassi S, Bisconti M, Martinet B, Arcolia V, Simon JF, Wattiez R, Leroy B, Hennebert E
International journal of molecular sciences 2022 Jun 10;23(12)
International journal of molecular sciences 2022 Jun 10;23(12)
Eimeria falciformis secretes extracellular vesicles to modulate proinflammatory response during interaction with mouse intestinal epithelial cells.
Olajide JS, Xiong L, Yang S, Qu Z, Xu X, Yang B, Wang J, Liu B, Ma X, Cai J
Parasites & vectors 2022 Jul 8;15(1):245
Parasites & vectors 2022 Jul 8;15(1):245
miR-126-3p containing exosomes derived from human umbilical cord mesenchymal stem cells promote angiogenesis and attenuate ovarian granulosa cell apoptosis in a preclinical rat model of premature ovarian failure.
Qu Q, Liu L, Cui Y, Liu H, Yi J, Bing W, Liu C, Jiang D, Bi Y
Stem cell research & therapy 2022 Jul 26;13(1):352
Stem cell research & therapy 2022 Jul 26;13(1):352
Magnetic hyperthermia induces effective and genuine immunogenic tumor cell death with respect to exogenous heating.
Yan B, Liu C, Wang S, Li H, Jiao J, Lee WSV, Zhang S, Hou Y, Hou Y, Ma X, Fan H, Lv Y, Liu X
Journal of materials chemistry. B 2022 Jul 20;10(28):5364-5374
Journal of materials chemistry. B 2022 Jul 20;10(28):5364-5374
Monitoring Protein Import into the Endoplasmic Reticulum in Living Cells with Proximity Labeling.
Lyu Z, Sycks MM, Espinoza MF, Nguyen KK, Montoya MR, Galapate CM, Mei L, Genereux JC
ACS chemical biology 2022 Jul 15;17(7):1963-1977
ACS chemical biology 2022 Jul 15;17(7):1963-1977
Fine-Tuning of Cholesterol Homeostasis Controls Erythroid Differentiation.
Lu Z, Huang L, Li Y, Xu Y, Zhang R, Zhou Q, Sun Q, Lu Y, Chen J, Shen Y, Li J, Zhao B
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2022 Jan;9(2):e2102669
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2022 Jan;9(2):e2102669
PKM2 compensates for proteasome dysfunction by mediating the formation of the CHIP-HSP70-BAG3 complex and the aggregation of ubiquitinated proteins.
Zhang C, Tang Q, Xia H, Xu H, Bi F
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2022 Jan;36(1):e22121
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2022 Jan;36(1):e22121
Pharmacological inhibition of BAG3-HSP70 with the proposed cancer therapeutic JG-98 is toxic for cardiomyocytes.
Martin TG, Delligatti CE, Muntu NA, Stachowski-Doll MJ, Kirk JA
Journal of cellular biochemistry 2022 Jan;123(1):128-141
Journal of cellular biochemistry 2022 Jan;123(1):128-141
Zinc Protects against Heat Stress-Induced Apoptosis via the Inhibition of Endoplasmic Reticulum Stress in TM3 Leydig Cells.
Xiong Y, Li J, He S
Biological trace element research 2022 Feb;200(2):728-739
Biological trace element research 2022 Feb;200(2):728-739
Exosomes released from Sertoli cells contribute to the survival of Leydig cells through CCL20 in rats.
Ma Y, Zhou Y, Zou SS, Sun Y, Chen XF
Molecular human reproduction 2022 Feb 4;28(2)
Molecular human reproduction 2022 Feb 4;28(2)
VPA and TSA Interrupt the Interplay between mutp53 and HSP70, Leading to CHK1 and RAD51 Down-Regulation and Sensitizing Pancreatic Cancer Cells to AZD2461 PARP Inhibitor.
Romeo MA, Gilardini Montani MS, Benedetti R, Arena A, D'Orazi G, Cirone M
International journal of molecular sciences 2022 Feb 18;23(4)
International journal of molecular sciences 2022 Feb 18;23(4)
Hypoxia-Preconditioned Extracellular Vesicles from Mesenchymal Stem Cells Improve Cartilage Repair in Osteoarthritis.
Zhang B, Tian X, Qu Z, Hao J, Zhang W
Membranes 2022 Feb 16;12(2)
Membranes 2022 Feb 16;12(2)
Exosomes derived from M2 type tumor-associated macrophages promote osimertinib resistance in non-small cell lung cancer through MSTRG.292666.16-miR-6836-5p-MAPK8IP3 axis.
Wan X, Xie B, Sun H, Gu W, Wang C, Deng Q, Zhou S
Cancer cell international 2022 Feb 15;22(1):83
Cancer cell international 2022 Feb 15;22(1):83
Regorafenib and reactive metabolite of sunitinib activate inflammasomes: Implications for multi tyrosine kinase inhibitor-Iiduced immune related adverse events.
Kato R, Ijiri Y
Die Pharmazie 2022 Feb 1;77(2):54-58
Die Pharmazie 2022 Feb 1;77(2):54-58
Exosomes derived from human umbilical cord mesenchymal stem cells protect against papain-induced emphysema by preventing apoptosis through activating VEGF-VEGFR2-mediated AKT and MEK/ERK pathways in rats.
Chen Q, Lin J, Deng Z, Qian W
Regenerative therapy 2022 Dec;21:216-224
Regenerative therapy 2022 Dec;21:216-224
Anserine and Carnosine Induce HSP70-Dependent H(2)S Formation in Endothelial Cells and Murine Kidney.
Wetzel C, Pfeffer T, Bulkescher R, Zemva J, Modafferi S, Polimeni A, Salinaro AT, Calabrese V, Schmitt CP, Peters V
Antioxidants (Basel, Switzerland) 2022 Dec 28;12(1)
Antioxidants (Basel, Switzerland) 2022 Dec 28;12(1)
Effect of miR-143-3p from Extracellular Vesicles of Porcine Uterine Luminal Fluid on Porcine Trophoblast Cells.
Ding Y, Hu Q, Gan J, Zang X, Gu T, Wu Z, Cai G, Hong L
Animals : an open access journal from MDPI 2022 Dec 2;12(23)
Animals : an open access journal from MDPI 2022 Dec 2;12(23)
Effects of the probiotic, Lactobacillus rhamnosus GG, on ulcer pathogenesis, HSP70 stress protein and nitric oxide levels in stress induced ulcer.
Isik M, Ozbayer C, Donmez DB, Colak E, Ustuner MC, Erol K, Degirmenci I
Biotechnic & histochemistry : official publication of the Biological Stain Commission 2022 Aug;97(6):449-460
Biotechnic & histochemistry : official publication of the Biological Stain Commission 2022 Aug;97(6):449-460
Human breast milk-derived exosomes through inhibiting AT II cell apoptosis to prevent bronchopulmonary dysplasia in rat lung.
Zhou Y, Liu Y, Xu G, Liu L, Li H, Li Y, Yin J, Wang X, Yu Z
Journal of cellular and molecular medicine 2022 Aug;26(15):4169-4182
Journal of cellular and molecular medicine 2022 Aug;26(15):4169-4182
Jianpi Huayu decoction inhibits the epithelial-mesenchymal transition of hepatocellular carcinoma cells by suppressing exosomal miR-23a-3p/Smad signaling.
Xie CF, Feng KL, Wang JN, Luo R, Fang CK, Zhang Y, Shen CP, Zhong C
Journal of ethnopharmacology 2022 Aug 10;294:115360
Journal of ethnopharmacology 2022 Aug 10;294:115360
The alleviative effect of thyroid hormone on cold stress-induced apotosis via HSP70 and mitochondrial apoptosis signal pathway in bovine Sertoli cells.
Zhang H, Huang H, Zheng P, Feng R, Wang X, Huang F, Ma M, Tian Y, Zhang G
Cryobiology 2022 Apr;105:63-70
Cryobiology 2022 Apr;105:63-70
Nicotinamide mononucleotide alleviates heat stress-induced oxidative stress and apoptosis in BMECs through reducing mitochondrial damage and endoplasmic reticulum stress.
Zeng HF, Xu J, Wang XL, Li SJ, Han ZY
Ecotoxicology and environmental safety 2022 Apr 15;235:113441
Ecotoxicology and environmental safety 2022 Apr 15;235:113441
Distinct Gene Expression Patterns of Two Heat Shock Protein 70 Members During Development, Diapause, and Temperature Stress in the Freshwater Crustacean Daphnia magna.
Chen L, Gómez R, Weiss LC
Frontiers in cell and developmental biology 2021;9:692517
Frontiers in cell and developmental biology 2021;9:692517
Exosomes Isolated From Bone Marrow Mesenchymal Stem Cells Exert a Protective Effect on Osteoarthritis via lncRNA LYRM4-AS1-GRPR-miR-6515-5p.
Wang X, Li Z, Cui Y, Cui X, Chen C, Wang Z
Frontiers in cell and developmental biology 2021;9:644380
Frontiers in cell and developmental biology 2021;9:644380
The Formation of Melanocyte Apoptotic Bodies in Vitiligo and the Relocation of Vitiligo Autoantigens under Oxidative Stress.
Tian J, Wang Y, Ding M, Zhang Y, Chi J, Wang T, Jiao B, Jian Z, Yi X, Huang Y, Liu L, Li K, Chen J, Wang G, Gao T, Li C, Li Q
Oxidative medicine and cellular longevity 2021;2021:7617839
Oxidative medicine and cellular longevity 2021;2021:7617839
Long Noncoding RNA RP11-115N4.1 Promotes Inflammatory Responses by Interacting With HNRNPH3 and Enhancing the Transcription of HSP70 in Unexplained Recurrent Spontaneous Abortion.
Liu M, Sun X, Zhu L, Zhu M, Deng K, Nie X, Mo H, Du T, Huang B, Hu L, Liang L, Wang D, Luo Y, Yi J, Zhang J, Zhong X, Cao C, Chen H
Frontiers in immunology 2021;12:717785
Frontiers in immunology 2021;12:717785
LncRNA FOXP4-AS1 Promotes Progression of Ewing Sarcoma and Is Associated With Immune Infiltrates.
Xiong J, Wu L, Huang L, Wu C, Liu Z, Deng W, Ma S, Zhou Z, Yu H, Cao K
Frontiers in oncology 2021;11:718876
Frontiers in oncology 2021;11:718876
Exogenous H(2) S prevents the nuclear translocation of PDC-E1 and inhibits vascular smooth muscle cell proliferation in the diabetic state.
Zhang L, Jiang X, Liu N, Li M, Kang J, Chen L, Tang J, Dong S, Lu F, Zhang W
Journal of cellular and molecular medicine 2021 Sep;25(17):8201-8214
Journal of cellular and molecular medicine 2021 Sep;25(17):8201-8214
Regulating immune memory and reversing tumor thermotolerance through a step-by-step starving-photothermal therapy.
Luo L, Qin B, Jiang M, Xie L, Luo Z, Guo X, Zhang J, Li X, Zhu C, Du Y, Peng L, You J
Journal of nanobiotechnology 2021 Sep 30;19(1):297
Journal of nanobiotechnology 2021 Sep 30;19(1):297
Differential Expression Pattern of Goat Uterine Fluids Extracellular Vesicles miRNAs during Peri-Implantation.
Xie Y, Liu G, Zang X, Hu Q, Zhou C, Li Y, Liu D, Hong L
Cells 2021 Sep 3;10(9)
Cells 2021 Sep 3;10(9)
SIRT3 protects bovine mammary epithelial cells from heat stress damage by activating the AMPK signaling pathway.
Sun XC, Wang Y, Zeng HF, Xi YM, Lin H, Han ZY, Chen KL
Cell death discovery 2021 Oct 21;7(1):304
Cell death discovery 2021 Oct 21;7(1):304
Repair of peripheral nerve defects by nerve grafts incorporated with extracellular vesicles from skin-derived precursor Schwann cells.
Yu M, Gu G, Cong M, Du M, Wang W, Shen M, Zhang Q, Shi H, Gu X, Ding F
Acta biomaterialia 2021 Oct 15;134:190-203
Acta biomaterialia 2021 Oct 15;134:190-203
Melatonin potentiates the cytotoxic effect of Neratinib in HER2(+) breast cancer through promoting endocytosis and lysosomal degradation of HER2.
Liu Z, Sang X, Wang M, Liu Y, Liu J, Wang X, Liu P, Cheng H
Oncogene 2021 Nov;40(44):6273-6283
Oncogene 2021 Nov;40(44):6273-6283
GADD45β stabilized by direct interaction with HSP72 ameliorates insulin resistance and lipid accumulation.
Dong Y, Ma N, Fan L, Yuan L, Wu Q, Gong L, Tao Z, Chen J, Ren J
Pharmacological research 2021 Nov;173:105879
Pharmacological research 2021 Nov;173:105879
Dendrobium officinale Polysaccharide Alleviates Intestinal Inflammation by Promoting Small Extracellular Vesicle Packaging of miR-433-3p.
Liu H, Liang J, Zhong Y, Xiao G, Efferth T, Georgiev MI, Vargas-De-La-Cruz C, Bajpai VK, Caprioli G, Liu J, Lin J, Wu H, Peng L, Li Y, Ma L, Xiao J, Wang Q
Journal of agricultural and food chemistry 2021 Nov 17;69(45):13510-13523
Journal of agricultural and food chemistry 2021 Nov 17;69(45):13510-13523
Lipidomic Profiling of Human Milk Derived Exosomes and Their Emerging Roles in the Prevention of Necrotizing Enterocolitis.
Chen W, Chen X, Qian Y, Wang X, Zhou Y, Yan X, Yu B, Yao S, Yu Z, Zhu J, Han S
Molecular nutrition & food research 2021 May;65(10):e2000845
Molecular nutrition & food research 2021 May;65(10):e2000845
Dihydromyricetin attenuates heat stress-induced apoptosis in dairy cow mammary epithelial cells through suppressing mitochondrial dysfunction.
Wang HL, Xing GD, Qian Y, Sun XF, Zhong JF, Chen KL
Ecotoxicology and environmental safety 2021 May;214:112078
Ecotoxicology and environmental safety 2021 May;214:112078
Cardiomyocyte contractile impairment in heart failure results from reduced BAG3-mediated sarcomeric protein turnover.
Martin TG, Myers VD, Dubey P, Dubey S, Perez E, Moravec CS, Willis MS, Feldman AM, Kirk JA
Nature communications 2021 May 19;12(1):2942
Nature communications 2021 May 19;12(1):2942
Cytokine Profile in Plasma Extracellular Vesicles of Parkinson's Disease and the Association with Cognitive Function.
Chan L, Chung CC, Chen JH, Yu RC, Hong CT
Cells 2021 Mar 9;10(3)
Cells 2021 Mar 9;10(3)
Hypoxic tumor-derived exosomal circular RNA SETDB1 promotes invasive growth and EMT via the miR-7/Sp1 axis in lung adenocarcinoma.
Xu L, Liao WL, Lu QJ, Zhang P, Zhu J, Jiang GN
Molecular therapy. Nucleic acids 2021 Mar 5;23:1078-1092
Molecular therapy. Nucleic acids 2021 Mar 5;23:1078-1092
Osteosarcoma-derived exosomal miR-501-3p promotes osteoclastogenesis and aggravates bone loss.
Lin L, Wang H, Guo W, He E, Huang K, Zhao Q
Cellular signalling 2021 Jun;82:109935
Cellular signalling 2021 Jun;82:109935
UBQLN2-HSP70 axis reduces poly-Gly-Ala aggregates and alleviates behavioral defects in the C9ORF72 animal model.
Zhang K, Wang A, Zhong K, Qi S, Wei C, Shu X, Tu WY, Xu W, Xia C, Xiao Y, Chen A, Bai L, Zhang J, Luo B, Wang W, Shen C
Neuron 2021 Jun 16;109(12):1949-1962.e6
Neuron 2021 Jun 16;109(12):1949-1962.e6
Dual roles of HSP70 chaperone HSPA1 in quality control of nascent and newly synthesized proteins.
Tian G, Hu C, Yun Y, Yang W, Dubiel W, Cheng Y, Wolf DA
The EMBO journal 2021 Jul 1;40(13):e106183
The EMBO journal 2021 Jul 1;40(13):e106183
Seminal exosomal miR-210-3p as a potential marker of Sertoli cell damage in Varicocele.
Ma Y, Zhou Y, Xiao Q, Zou SS, Zhu YC, Ping P, Chen XF
Andrology 2021 Jan;9(1):451-459
Andrology 2021 Jan;9(1):451-459
The Role and Mechanism of Exosomes from Umbilical Cord Mesenchymal Stem Cells in Inducing Osteogenesis and Preventing Osteoporosis.
Yahao G, Xinjia W
Cell transplantation 2021 Jan-Dec;30:9636897211057465
Cell transplantation 2021 Jan-Dec;30:9636897211057465
The EGFR-HSF1 axis accelerates the tumorigenesis of pancreatic cancer.
Qian W, Chen K, Qin T, Xiao Y, Li J, Yue Y, Zhou C, Ma J, Duan W, Lei J, Han L, Li L, Shen X, Wu Z, Ma Q, Wang Z
Journal of experimental & clinical cancer research : CR 2021 Jan 9;40(1):25
Journal of experimental & clinical cancer research : CR 2021 Jan 9;40(1):25
Hsp90 is involved in pseudorabies virus virion assembly via stabilizing major capsid protein VP5.
Zhang WJ, Wang RQ, Li LT, Fu W, Chen HC, Liu ZF
Virology 2021 Jan 15;553:70-80
Virology 2021 Jan 15;553:70-80
Spermine Protects Cardiomyocytes from High Glucose-Induced Energy Disturbance by Targeting the CaSR-gp78-Ubiquitin Proteasome System.
Wang Y, Wang Y, Li F, Zhang X, Li H, Yang G, Xu C, Wei C
Cardiovascular drugs and therapy 2021 Feb;35(1):73-85
Cardiovascular drugs and therapy 2021 Feb;35(1):73-85
Boron Attenuates Heat Stress-Induced Apoptosis by Inhibiting Endoplasmic Reticulum Stress in Mouse Granulosa Cells.
Xiong Y, Jin E, Yin Q, Che C, He S
Biological trace element research 2021 Feb;199(2):611-621
Biological trace element research 2021 Feb;199(2):611-621
Small extracellular vesicle-mediated Hsp70 intercellular delivery enhances breast cancer adriamycin resistance.
Hu W, Xu Z, Zhu S, Sun W, Wang X, Tan C, Zhang Y, Zhang G, Xu Y, Tang J
Free radical biology & medicine 2021 Feb 20;164:85-95
Free radical biology & medicine 2021 Feb 20;164:85-95
Exosomes secreted from mesenchymal stem cells mediate the regeneration of endothelial cells treated with rapamycin by delivering pro-angiogenic microRNAs.
Wang W, Zhao Y, Li H, Zhang Y, Jia X, Wang C, Zhu P, Wang J, Hou Y
Experimental cell research 2021 Feb 1;399(1):112449
Experimental cell research 2021 Feb 1;399(1):112449
SKP-SC-EVs Mitigate Denervated Muscle Atrophy by Inhibiting Oxidative Stress and Inflammation and Improving Microcirculation.
Wang W, Shen D, Zhang L, Ji Y, Xu L, Chen Z, Shen Y, Gong L, Zhang Q, Shen M, Gu X, Sun H
Antioxidants (Basel, Switzerland) 2021 Dec 28;11(1)
Antioxidants (Basel, Switzerland) 2021 Dec 28;11(1)
Exosomal miR-193b-5p as a regulator of LPS-induced inflammation in dairy cow mammary epithelial cells.
Xu H, Zhang T, Hu X, Xie Y, Wu R, Lian S, Wang J
In vitro cellular & developmental biology. Animal 2021 Aug;57(7):695-703
In vitro cellular & developmental biology. Animal 2021 Aug;57(7):695-703
Augmentation of the heat shock axis during exceptional longevity in Ames dwarf mice.
Trivedi R, Knopf B, Tripathi JK, Rakoczy S, Manocha GD, Brown-Borg H, Jurivich DA
GeroScience 2021 Aug;43(4):1921-1934
GeroScience 2021 Aug;43(4):1921-1934
Recovery from heat shock requires the microRNA pathway in Caenorhabditis elegans.
Pagliuso DC, Bodas DM, Pasquinelli AE
PLoS genetics 2021 Aug;17(8):e1009734
PLoS genetics 2021 Aug;17(8):e1009734
A novel Hsp70 inhibitor specifically targeting the cancer-related Hsp70-Bim protein-protein interaction.
Wang Z, Song T, Guo Z, Uwituze LB, Guo Y, Zhang H, Wang H, Zhang X, Pan H, Ji T, Yin F, Zhou S, Dai J, Zhang Z
European journal of medicinal chemistry 2021 Aug 5;220:113452
European journal of medicinal chemistry 2021 Aug 5;220:113452
Amiodarone, Unlike Dronedarone, Activates Inflammasomes via Its Reactive Metabolites: Implications for Amiodarone Adverse Reactions.
Kato R, Ijiri Y, Hayashi T
Chemical research in toxicology 2021 Aug 16;34(8):1860-1865
Chemical research in toxicology 2021 Aug 16;34(8):1860-1865
Tubocapsenolide A targets C-terminal cysteine residues of HSP90 to exert the anti-tumor effect.
Zhu D, Li S, Chen C, Wang S, Zhu J, Kong L, Luo J
Pharmacological research 2021 Apr;166:105523
Pharmacological research 2021 Apr;166:105523
Adipose-derived stem cell exosomes facilitate rotator cuff repair by mediating tendon-derived stem cells.
Fu G, Lu L, Pan Z, Fan A, Yin F
Regenerative medicine 2021 Apr;16(4):359-372
Regenerative medicine 2021 Apr;16(4):359-372
Construction of Smart Nanotheranostic Platform Bi-Ag@PVP: Multimodal CT/PA Imaging-Guided PDT/PTT for Cancer Therapy.
Zhou Z, Xie J, Ma S, Luo X, Liu J, Wang S, Chen Y, Yan J, Luo F
ACS omega 2021 Apr 27;6(16):10723-10734
ACS omega 2021 Apr 27;6(16):10723-10734
S-allyl cysteine ameliorates heat stress-induced oxidative stress by activating Nrf2/HO-1 signaling pathway in BMECs.
Wang Y, Wang HL, Xing GD, Qian Y, Zhong JF, Chen KL
Toxicology and applied pharmacology 2021 Apr 1;416:115469
Toxicology and applied pharmacology 2021 Apr 1;416:115469
Hepatitis A virus structural protein pX interacts with ALIX and promotes the secretion of virions and foreign proteins through exosome-like vesicles.
Jiang W, Ma P, Deng L, Liu Z, Wang X, Liu X, Long G
Journal of extracellular vesicles 2020;9(1):1716513
Journal of extracellular vesicles 2020;9(1):1716513
TRIM16 Promotes Osteogenic Differentiation of Human Periodontal Ligament Stem Cells by Modulating CHIP-Mediated Degradation of RUNX2.
Zhao Y, Zhai Q, Liu H, Xi X, Chen S, Liu D
Frontiers in cell and developmental biology 2020;8:625105
Frontiers in cell and developmental biology 2020;8:625105
An Eight-CircRNA Assessment Model for Predicting Biochemical Recurrence in Prostate Cancer.
Wang S, Su W, Zhong C, Yang T, Chen W, Chen G, Liu Z, Wu K, Zhong W, Li B, Mao X, Lu J
Frontiers in cell and developmental biology 2020;8:599494
Frontiers in cell and developmental biology 2020;8:599494
Reactive metabolite of gefitinib activates inflammasomes: implications for gefitinib-induced idiosyncratic reaction.
Kato R, Ijiri Y, Hayashi T, Uetrecht J
The Journal of toxicological sciences 2020;45(11):673-680
The Journal of toxicological sciences 2020;45(11):673-680
Ultraviolet B irradiation enhances the secretion of exosomes by human primary melanocytes and changes their exosomal miRNA profile.
Shen Z, Sun J, Shao J, Xu J
PloS one 2020;15(8):e0237023
PloS one 2020;15(8):e0237023
Hsp90 inhibitor HSP990 in very low dose upregulates EAAT2 and exerts potent antiepileptic activity.
Sha L, Chen T, Deng Y, Du T, Ma K, Zhu W, Shen Y, Xu Q
Theranostics 2020;10(18):8415-8429
Theranostics 2020;10(18):8415-8429
Extracellular vesicle-mediated delivery of miR-101 inhibits lung metastasis in osteosarcoma.
Zhang K, Dong C, Chen M, Yang T, Wang X, Gao Y, Wang L, Wen Y, Chen G, Wang X, Yu X, Zhang Y, Wang P, Shang M, Han K, Zhou Y
Theranostics 2020;10(1):411-425
Theranostics 2020;10(1):411-425
circFMN2 Sponges miR-1238 to Promote the Expression of LIM-Homeobox Gene 2 in Prostate Cancer Cells.
Shan G, Shao B, Liu Q, Zeng Y, Fu C, Chen A, Chen Q
Molecular therapy. Nucleic acids 2020 Sep 4;21:133-146
Molecular therapy. Nucleic acids 2020 Sep 4;21:133-146
Multifactorial Attenuation of the Murine Heat Shock Response With Age.
Jurivich DA, Manocha GD, Trivedi R, Lizakowski M, Rakoczy S, Brown-Borg H
The journals of gerontology. Series A, Biological sciences and medical sciences 2020 Sep 25;75(10):1846-1852
The journals of gerontology. Series A, Biological sciences and medical sciences 2020 Sep 25;75(10):1846-1852
UBE2T-regulated H2AX monoubiquitination induces hepatocellular carcinoma radioresistance by facilitating CHK1 activation.
Sun J, Zhu Z, Li W, Shen M, Cao C, Sun Q, Guo Z, Liu L, Wu D
Journal of experimental & clinical cancer research : CR 2020 Oct 21;39(1):222
Journal of experimental & clinical cancer research : CR 2020 Oct 21;39(1):222
CDK5RAP3, a Novel Nucleoplasmic Shuttle, Deeply Regulates HSF1-Mediated Heat Stress Response and Protects Mammary Epithelial Cells from Heat Injury.
Shen Y, Zou Y, Li J, Chen F, Li H, Cai Y
International journal of molecular sciences 2020 Nov 9;21(21)
International journal of molecular sciences 2020 Nov 9;21(21)
Small extracellular vesicle-bound vascular endothelial growth factor secreted by carcinoma-associated fibroblasts promotes angiogenesis in a bevacizumab-resistant manner.
Li J, Liu X, Zang S, Zhou J, Zhang F, Sun B, Qi D, Li X, Kong J, Jin D, Yang X, Luo Y, Lu Y, Lin B, Niu W, Liu T
Cancer letters 2020 Nov 1;492:71-83
Cancer letters 2020 Nov 1;492:71-83
Exogenous spermine attenuates rat diabetic cardiomyopathy via suppressing ROS-p53 mediated downregulation of calcium-sensitive receptor.
Wang Y, Chen J, Li S, Zhang X, Guo Z, Hu J, Shao X, Song N, Zhao Y, Li H, Yang G, Xu C, Wei C
Redox biology 2020 May;32:101514
Redox biology 2020 May;32:101514
Liver-derived exosome-laden lncRNA MT1DP aggravates cadmium-induced nephrotoxicity.
Gao M, Dong Z, Sun J, Liu W, Xu M, Li C, Zhu P, Yang X, Shang X, Wu Y, Liu S
Environmental pollution (Barking, Essex : 1987) 2020 Mar;258:113717
Environmental pollution (Barking, Essex : 1987) 2020 Mar;258:113717
Light-activated oxygen self-supplied starving therapy in near-infrared (NIR) window and adjuvant hyperthermia-induced tumor ablation with an augmented sensitivity.
Ren J, Zhang L, Zhang J, Zhang W, Cao Y, Xu Z, Cui H, Kang Y, Xue P
Biomaterials 2020 Mar;234:119771
Biomaterials 2020 Mar;234:119771
Heat Stress Impairs the Physiological Responses and Regulates Genes Coding for Extracellular Exosomal Proteins in Rat.
Dou J, Khan A, Khan MZ, Mi S, Wang Y, Yu Y, Wang Y
Genes 2020 Mar 13;11(3)
Genes 2020 Mar 13;11(3)
Exosomes carrying ALDOA and ALDH3A1 from irradiated lung cancer cells enhance migration and invasion of recipients by accelerating glycolysis.
Wang C, Xu J, Yuan D, Bai Y, Pan Y, Zhang J, Shao C
Molecular and cellular biochemistry 2020 Jun;469(1-2):77-87
Molecular and cellular biochemistry 2020 Jun;469(1-2):77-87
Tumor-Derived EV-Encapsulated miR-181b-5p Induces Angiogenesis to Foster Tumorigenesis and Metastasis of ESCC.
Wang Y, Lu J, Chen L, Bian H, Hu J, Li D, Xia C, Xu H
Molecular therapy. Nucleic acids 2020 Jun 5;20:421-437
Molecular therapy. Nucleic acids 2020 Jun 5;20:421-437
Circulating Exosomes From Lipopolysaccharide-Induced Ards Mice Trigger Endoplasmic Reticulum Stress in Lung Tissue.
Tang X, Yu Q, Wen X, Qi D, Peng J, He J, Deng W, Zhu T, Zhao Y, Wang D
Shock (Augusta, Ga.) 2020 Jul;54(1):110-118
Shock (Augusta, Ga.) 2020 Jul;54(1):110-118
CaCBL1 Acts as a Positive Regulator in Pepper Response to Ralstonia solanacearum.
Shen L, Yang S, Yang F, Guan D, He S
Molecular plant-microbe interactions : MPMI 2020 Jul;33(7):945-957
Molecular plant-microbe interactions : MPMI 2020 Jul;33(7):945-957
LASP1 promotes proliferation, metastasis, invasion in head and neck squamous cell carcinoma and through direct interaction with HSPA1A.
Chen Q, Wu K, Qin X, Yu Y, Wang X, Wei K
Journal of cellular and molecular medicine 2020 Jan;24(2):1626-1639
Journal of cellular and molecular medicine 2020 Jan;24(2):1626-1639
Selenium Attenuates Chronic Heat Stress-Induced Apoptosis via the Inhibition of Endoplasmic Reticulum Stress in Mouse Granulosa Cells.
Xiong Y, Yin Q, Jin E, Chen H, He S
Molecules (Basel, Switzerland) 2020 Jan 28;25(3)
Molecules (Basel, Switzerland) 2020 Jan 28;25(3)
Enterovirus A71 capsid protein VP1 increases blood-brain barrier permeability and virus receptor vimentin on the brain endothelial cells.
Wang W, Sun J, Wang N, Sun Z, Ma Q, Li J, Zhang M, Xu J
Journal of neurovirology 2020 Feb;26(1):84-94
Journal of neurovirology 2020 Feb;26(1):84-94
Extracellular Vesicles from Hyperammonemic Rats Induce Neuroinflammation and Motor Incoordination in Control Rats.
Izquierdo-Altarejos P, Cabrera-Pastor A, Gonzalez-King H, Montoliu C, Felipo V
Cells 2020 Feb 28;9(3)
Cells 2020 Feb 28;9(3)
Hepatic DNAJB9 Drives Anabolic Biasing to Reduce Steatosis and Obesity.
Sun F, Liao Y, Qu X, Xiao X, Hou S, Chen Z, Huang H, Li P, Fu S
Cell reports 2020 Feb 11;30(6):1835-1847.e9
Cell reports 2020 Feb 11;30(6):1835-1847.e9
Extracellular vesicles from skin precursor-derived Schwann cells promote axonal outgrowth and regeneration of motoneurons via Akt/mTOR/p70S6K pathway.
Wu X, Wang L, Cong M, Shen M, He Q, Ding F, Shi H
Annals of translational medicine 2020 Dec;8(24):1640
Annals of translational medicine 2020 Dec;8(24):1640
Heat stress activates YAP/TAZ to induce the heat shock transcriptome.
Luo M, Meng Z, Moroishi T, Lin KC, Shen G, Mo F, Shao B, Wei X, Zhang P, Wei Y, Guan KL
Nature cell biology 2020 Dec;22(12):1447-1459
Nature cell biology 2020 Dec;22(12):1447-1459
Antagomirs targeting miR-142-5p attenuate pilocarpine-induced status epilepticus in mice.
Zhang H, Lian Y, Xie N, Cheng X, Chen C, Xu H, Zheng Y
Experimental cell research 2020 Aug 15;393(2):112089
Experimental cell research 2020 Aug 15;393(2):112089
Heat stress induces apoptosis through disruption of dynamic mitochondrial networks in dairy cow mammary epithelial cells.
Chen KL, Wang HL, Jiang LZ, Qian Y, Yang CX, Chang WW, Zhong JF, Xing GD
In vitro cellular & developmental biology. Animal 2020 Apr;56(4):322-331
In vitro cellular & developmental biology. Animal 2020 Apr;56(4):322-331
Rosmarinic acid exerts a neuroprotective effect on spinal cord injury by suppressing oxidative stress and inflammation via modulating the Nrf2/HO-1 and TLR4/NF-κB pathways.
Ma Z, Lu Y, Yang F, Li S, He X, Gao Y, Zhang G, Ren E, Wang Y, Kang X
Toxicology and applied pharmacology 2020 Apr 19;397:115014
Toxicology and applied pharmacology 2020 Apr 19;397:115014
Adipose-derived exosomes protect the pulmonary endothelial barrier in ventilator-induced lung injury by inhibiting the TRPV4/Ca(2+) signaling pathway.
Yu Q, Wang D, Wen X, Tang X, Qi D, He J, Zhao Y, Deng W, Zhu T
American journal of physiology. Lung cellular and molecular physiology 2020 Apr 1;318(4):L723-L741
American journal of physiology. Lung cellular and molecular physiology 2020 Apr 1;318(4):L723-L741
Hypoxia preconditioned renal tubular epithelial cell-derived extracellular vesicles alleviate renal ischaemia-reperfusion injury mediated by the HIF-1α/Rab22 pathway and potentially affected by microRNAs.
Zhang L, Liu H, Xu K, Ling Z, Huang Y, Hu Q, Lu K, Liu C, Wang Y, Liu N, Zhang X, Xu B, Wu J, Chen S, Zhang G, Chen M
International journal of biological sciences 2019;15(6):1161-1176
International journal of biological sciences 2019;15(6):1161-1176
(-)-Oleocanthal and (-)-oleocanthal-rich olive oils induce lysosomal membrane permeabilization in cancer cells.
Goren L, Zhang G, Kaushik S, Breslin PAS, Du YN, Foster DA
PloS one 2019;14(8):e0216024
PloS one 2019;14(8):e0216024
The Capsid Protein VP1 of Coxsackievirus B Induces Cell Cycle Arrest by Up-Regulating Heat Shock Protein 70.
Wang Y, Zhao S, Chen Y, Wang T, Dong C, Wo X, Zhang J, Dong Y, Xu W, Feng X, Qu C, Wang Y, Zhong Z, Zhao W
Frontiers in microbiology 2019;10:1633
Frontiers in microbiology 2019;10:1633
Mapping Interactome Networks of DNAJC11, a Novel Mitochondrial Protein Causing Neuromuscular Pathology in Mice.
Violitzi F, Perivolidi VI, Thireou T, Grivas I, Haralambous S, Samiotaki M, Panayotou G, Douni E
Journal of proteome research 2019 Nov 1;18(11):3896-3912
Journal of proteome research 2019 Nov 1;18(11):3896-3912
Hepatitis B virus-regulated growth of liver cancer cells occurs through the microRNA-340-5p-activating transcription factor 7-heat shock protein A member 1B axis.
Song F, Wei M, Wang J, Liu Y, Guo M, Li X, Luo J, Zhou J, Wang M, Guo D, Chen L, Sun G
Cancer science 2019 May;110(5):1633-1643
Cancer science 2019 May;110(5):1633-1643
An acquired scaffolding function of the DNAJ-PKAc fusion contributes to oncogenic signaling in fibrolamellar carcinoma.
Turnham RE, Smith FD, Kenerson HL, Omar MH, Golkowski M, Garcia I, Bauer R, Lau HT, Sullivan KM, Langeberg LK, Ong SE, Riehle KJ, Yeung RS, Scott JD
eLife 2019 May 7;8
eLife 2019 May 7;8
The circRNA circPTPRA suppresses epithelial-mesenchymal transitioning and metastasis of NSCLC cells by sponging miR-96-5p.
Wei S, Zheng Y, Jiang Y, Li X, Geng J, Shen Y, Li Q, Wang X, Zhao C, Chen Y, Qian Z, Zhou J, Li W
EBioMedicine 2019 Jun;44:182-193
EBioMedicine 2019 Jun;44:182-193
Bioinspired extracellular vesicles embedded with black phosphorus for molecular recognition-guided biomineralization.
Wang Y, Hu X, Zhang L, Zhu C, Wang J, Li Y, Wang Y, Wang C, Zhang Y, Yuan Q
Nature communications 2019 Jun 27;10(1):2829
Nature communications 2019 Jun 27;10(1):2829
Elevated levels of circulating ITIH4 are associated with hepatocellular carcinoma with nonalcoholic fatty liver disease: from pig model to human study.
Nakamura N, Hatano E, Iguchi K, Sato M, Kawaguchi H, Ohtsu I, Sakurai T, Aizawa N, Iijima H, Nishiguchi S, Tomono T, Okuda Y, Wada S, Seo S, Taura K, Uemoto S, Ikegawa M
BMC cancer 2019 Jun 25;19(1):621
BMC cancer 2019 Jun 25;19(1):621
The up-regulation of two identified wound healing specific proteins-HSP70 and lysozyme in regenerated Eisenia fetida through transcriptome analysis.
Yang Y, Sun Y, Zhang N, Li J, Zhang C, Duan X, Ding Y, Zhao R, Zheng Z, Geng D, Sun Y
Journal of ethnopharmacology 2019 Jun 12;237:64-73
Journal of ethnopharmacology 2019 Jun 12;237:64-73
The exosome-like vesicles from osteoarthritic chondrocyte enhanced mature IL-1β production of macrophages and aggravated synovitis in osteoarthritis.
Ni Z, Kuang L, Chen H, Xie Y, Zhang B, Ouyang J, Wu J, Zhou S, Chen L, Su N, Tan Q, Luo X, Chen B, Chen S, Yin L, Huang H, Du X, Chen L
Cell death & disease 2019 Jul 8;10(7):522
Cell death & disease 2019 Jul 8;10(7):522
HMGB1-mediated differential response on hippocampal neurotransmitter disorder and neuroinflammation in adolescent male and female mice following cold exposure.
Xu B, Zang SC, Li SZ, Guo JR, Wang JF, Wang D, Zhang LP, Yang HM, Lian S
Brain, behavior, and immunity 2019 Feb;76:223-235
Brain, behavior, and immunity 2019 Feb;76:223-235
Exosomes from glioma cells induce a tumor-like phenotype in mesenchymal stem cells by activating glycolysis.
Ma Z, Cui X, Lu L, Chen G, Yang Y, Hu Y, Lu Y, Cao Z, Wang Y, Wang X
Stem cell research & therapy 2019 Feb 15;10(1):60
Stem cell research & therapy 2019 Feb 15;10(1):60
Design, synthesis and molecular mechanisms of novel dual inhibitors of heat shock protein 90/phosphoinositide 3-kinase alpha (Hsp90/PI3Kα) against cutaneous melanoma.
Qin F, Wang Y, Jiang X, Wang Y, Zhang N, Wen X, Wang L, Jiang Q, He G
Journal of enzyme inhibition and medicinal chemistry 2019 Dec;34(1):909-926
Journal of enzyme inhibition and medicinal chemistry 2019 Dec;34(1):909-926
Necroptosis promotes autophagy-dependent upregulation of DAMP and results in immunosurveillance.
Lin SY, Hsieh SY, Fan YT, Wei WC, Hsiao PW, Tsai DH, Wu TS, Yang NS
Autophagy 2018;14(5):778-795
Autophagy 2018;14(5):778-795
Inhibition of Heat Shock Protein 90 by 17-AAG Reduces Inflammation via P2X7 Receptor/NLRP3 Inflammasome Pathway and Increases Neurogenesis After Subarachnoid Hemorrhage in Mice.
Zuo Y, Wang J, Liao F, Yan X, Li J, Huang L, Liu F
Frontiers in molecular neuroscience 2018;11:401
Frontiers in molecular neuroscience 2018;11:401
Circulating exosomes contain protein biomarkers of metastatic non-small-cell lung cancer.
Wang N, Song X, Liu L, Niu L, Wang X, Song X, Xie L
Cancer science 2018 May;109(5):1701-1709
Cancer science 2018 May;109(5):1701-1709
A proteomic approach reveals the differential protein expression in Drosophila melanogaster treated with red ginseng extract (Panax ginseng).
Liu QX, Zhang W, Wang J, Hou W, Wang YP
Journal of ginseng research 2018 Jul;42(3):343-351
Journal of ginseng research 2018 Jul;42(3):343-351
Curcumin inhibits liver cancer by inhibiting DAMP molecule HSP70 and TLR4 signaling.
Ren B, Luo S, Tian X, Jiang Z, Zou G, Xu F, Yin T, Huang Y, Liu J
Oncology reports 2018 Aug;40(2):895-901
Oncology reports 2018 Aug;40(2):895-901
Effects of Boron Supplementation on Expression of Hsp70 in the Spleen of African Ostrich.
Haseeb K, Wang J, Xiao K, Yang KL, Sun PP, Wu XT, Luo Y, Song H, Liu HZ, Zhong JM, Peng KM
Biological trace element research 2018 Apr;182(2):317-327
Biological trace element research 2018 Apr;182(2):317-327
Uncoupling of Metabolic Health from Longevity through Genetic Alteration of Adipose Tissue Lipid-Binding Proteins.
Charles KN, Li MD, Engin F, Arruda AP, Inouye K, Hotamisligil GS
Cell reports 2017 Oct 10;21(2):393-402
Cell reports 2017 Oct 10;21(2):393-402
HSP90 recognizes the N-terminus of huntingtin involved in regulation of huntingtin aggregation by USP19.
He WT, Xue W, Gao YG, Hong JY, Yue HW, Jiang LL, Hu HY
Scientific reports 2017 Nov 1;7(1):14797
Scientific reports 2017 Nov 1;7(1):14797
Calcium sensing receptor protects high glucose-induced energy metabolism disorder via blocking gp78-ubiquitin proteasome pathway.
Wang Y, Gao P, Wei C, Li H, Zhang L, Zhao Y, Wu B, Tian Y, Zhang W, Wu L, Wang R, Xu C
Cell death & disease 2017 May 18;8(5):e2799
Cell death & disease 2017 May 18;8(5):e2799
A comparative proteomic analysis reveals important proteins for the fertilization and early embryonic development of the oyster Crassostrea gigas.
Huang X, Huan P, Liu B
Proteomics 2017 Jan;17(1-2)
Proteomics 2017 Jan;17(1-2)
Multifunctional WS(2) @Poly(ethylene imine) Nanoplatforms for Imaging Guided Gene-Photothermal Synergistic Therapy of Cancer.
Zhang C, Yong Y, Song L, Dong X, Zhang X, Liu X, Gu Z, Zhao Y, Hu Z
Advanced healthcare materials 2016 Nov;5(21):2776-2787
Advanced healthcare materials 2016 Nov;5(21):2776-2787
Interferon α Induces the Apoptosis of Cervical Cancer HeLa Cells by Activating both the Intrinsic Mitochondrial Pathway and Endoplasmic Reticulum Stress-Induced Pathway.
Shi WY, Cao C, Liu L
International journal of molecular sciences 2016 Nov 2;17(11)
International journal of molecular sciences 2016 Nov 2;17(11)
Modification of the hTERT promoter by heat shock elements enhances the efficiency and specificity of cancer targeted gene therapy.
Wang X, Zhou P, Sun X, Wei G, Zhang L, Wang H, Yao J, Jia P, Zheng J
International journal of hyperthermia : the official journal of European Society for Hyperthermic Oncology, North American Hyperthermia Group 2016 May;32(3):244-53
International journal of hyperthermia : the official journal of European Society for Hyperthermic Oncology, North American Hyperthermia Group 2016 May;32(3):244-53
Changes in gene expression and content of Hsp70 and Hsp90 in striated muscles of mice after 30-day space flight on the biosatellite Bion-M1.
Gritsyna YV, Abdusalamova ZR, Vikhlyantsev IM, Ulanova AD, Shenkman BS, Podlubnaya ZA, Kozlovskaya IB
Doklady. Biochemistry and biophysics 2015;463:199-202
Doklady. Biochemistry and biophysics 2015;463:199-202
Identification of Hsf1 as a novel androgen receptor-regulated gene in mouse Sertoli cells.
Yang L, Wang Y, Zhang Q, Lai Y, Li C, Zhang Q, Huang W, Duan Y, Jiang Z, Li X, Cai Z, Mou L, Gui Y
Molecular reproduction and development 2014 Jun;81(6):514-23
Molecular reproduction and development 2014 Jun;81(6):514-23
Role of the nucleus tractus solitarii in the protection of pre-moxibustion on gastric mucosal lesions.
Peng L, Liu M, Chang X, Yang Z, Yi S, Yan J, Peng Y
Neural regeneration research 2014 Jan 15;9(2):198-204
Neural regeneration research 2014 Jan 15;9(2):198-204
Effects of pre-moxibustion at Zusanli (ST36) on heat shock protein 70 expression in rats with gastric mucosal lesions after neurotomy.
Peng L, Liu M, Chang X, Yang Z, Yi S, Yan J, Peng Y
Neural regeneration research 2012 Oct 25;7(30):2370-6
Neural regeneration research 2012 Oct 25;7(30):2370-6
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Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- The HSP70 antibody from Proteintech is a rabbit polyclonal antibody to a recombinant protein of human HSP70. This antibody recognizes human,mouse,rat antigen. The HSP70 antibody has been validated for the following applications: ELISA, IHC, WB, IF analysis.
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- Immunofluorescent analysis of HepG2 cells, using HSPA1A antibody 10995-1-AP at 1:50 dilution and Rhodamine-labeled goat anti-rabbit IgG (red). Blue pseudocolor = DAPI (fluorescent DNA dye).
- Sample type
- cell line
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- Immunohistochemical of paraffin-embedded human prostate cancer using 10995-1-AP(HSP70 antibody) at dilution of 1:100 (under 10x lens)
- Sample type
- tissue
