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- Antigen structure
- References [13]
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- Validations
- Immunohistochemistry [2]
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- Product number
- 13876-1-AP - Provider product page
- Provider
- Proteintech Group
- Product name
- Desmocollin 2 antibody
- Antibody type
- Polyclonal
- Description
- Desmocollin 2 antibody (Cat. #13876-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse and has been validated for the following applications: IF, IHC, WB, ELISA.
- Reactivity
- Human, Mouse
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references Proteomic analysis across Healthy-NAT-Tumor tissues uncovers clinically relevant biological events in esophageal squamous cell carcinoma.
Empagliflozin Preserves Cardiomyocyte Structural Homeostasis via the Stabilization of the Integrin α5-Desmocollin-2 Adhesion Axis in Sepsis-Induced Cardiomyopathy.
ATG5-dependent autophagy in Sertoli cells protects against cadmium-disrupted blood-testis barrier via perturbing CXCL2/CXCR2 axis.
Mitochondrial ROS-associated integrated stress response is involved in arsenic-induced blood-testis barrier disruption and protective effect of melatonin.
Excessive MYC Orchestrates Macrophages induced Chromatin Remodeling to Sustain Micropapillary-Patterned Malignancy in Lung Adenocarcinoma.
Protein arginine methyltransferase 1 stimulates basal cell proliferation and migration to maintain corneal epithelial homeostasis.
Suppressed testicular macrophage M1 polarization by HDAC5 enforces insensitivity to LPS-elicited blood-testis barrier damage.
Desmoglein 2 and desmocollin 2 depletions promote malignancy through distinct mechanisms in triple-negative and luminal breast cancer.
Transforms of Cell Surface Glycoproteins Charge Influences Tumor Cell Metastasis via Atypically Inhibiting Epithelial-Mesenchymal Transition Including Matrix Metalloproteinases and Cell Junctions.
Exosomal miR-205-5p enhances angiogenesis and nasopharyngeal carcinoma metastasis by targeting desmocollin-2.
Environmental cadmium impairs blood-testis barrier via activating HRI-responsive mitochondrial stress in mice.
Mapping of truncated O-glycans in cancers of epithelial and non-epithelial origin.
Essential Functions of Glycans in Human Epithelia Dissected by a CRISPR-Cas9-Engineered Human Organotypic Skin Model.
Liu W, Wang W, Zheng DW, Ran YQ, Feng MX, Deng DX, Xu XE, Xu LY, Huang HH, Li EM
Briefings in bioinformatics 2026 Mar 1;27(2)
Briefings in bioinformatics 2026 Mar 1;27(2)
Empagliflozin Preserves Cardiomyocyte Structural Homeostasis via the Stabilization of the Integrin α5-Desmocollin-2 Adhesion Axis in Sepsis-Induced Cardiomyopathy.
Qiao G, Lu Y, Wu J, Ren C, Liu M, Liang S, Zhang C
Cells 2025 Sep 16;14(18)
Cells 2025 Sep 16;14(18)
ATG5-dependent autophagy in Sertoli cells protects against cadmium-disrupted blood-testis barrier via perturbing CXCL2/CXCR2 axis.
Li H, Hu YF, Wang XR, Hong JW, Zhang ZY, Zou YH, Cheng XY, Luo YX, Zhang XD, Zhu HL, Xiong YW, Chang W, Wang H, Yang L
Cell biology and toxicology 2025 Oct 24;41(1):143
Cell biology and toxicology 2025 Oct 24;41(1):143
Mitochondrial ROS-associated integrated stress response is involved in arsenic-induced blood-testis barrier disruption and protective effect of melatonin.
Niu FW, Liu MD, Yao K, Yang R, Gao L, Zhai JX, Wang C, Zhang SH, Xu DX, Zhang ZH
Environment international 2025 Mar;197:109346
Environment international 2025 Mar;197:109346
Excessive MYC Orchestrates Macrophages induced Chromatin Remodeling to Sustain Micropapillary-Patterned Malignancy in Lung Adenocarcinoma.
Song X, Pan Z, Zhang Y, Yang W, Zhang T, Wang H, Chen Y, Yu X, Ding H, Li R, Ge P, Xu L, Dong G, Jiang F
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2025 Mar;12(12):e2403851
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2025 Mar;12(12):e2403851
Protein arginine methyltransferase 1 stimulates basal cell proliferation and migration to maintain corneal epithelial homeostasis.
Yang J, Hu M, Yang M, Ni H, Zhou J, Li D, Ran J, Liu M
Cell death discovery 2025 Aug 15;11(1):385
Cell death discovery 2025 Aug 15;11(1):385
Suppressed testicular macrophage M1 polarization by HDAC5 enforces insensitivity to LPS-elicited blood-testis barrier damage.
Li H, Hu YF, Wang XR, Ouyang KW, Wang H, Wang KW, Chang W, Zhang J, Yuan Z, Xiong YW, Zhu HL, Yang L, Wang H
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 2024 Oct;192:114940
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 2024 Oct;192:114940
Desmoglein 2 and desmocollin 2 depletions promote malignancy through distinct mechanisms in triple-negative and luminal breast cancer.
Han JY, Che N, Mo J, Zhang DF, Liang XH, Dong XY, Zhao XL, Sun BC
BMC cancer 2024 Apr 26;24(1):532
BMC cancer 2024 Apr 26;24(1):532
Transforms of Cell Surface Glycoproteins Charge Influences Tumor Cell Metastasis via Atypically Inhibiting Epithelial-Mesenchymal Transition Including Matrix Metalloproteinases and Cell Junctions.
Wang M, Kejian S, Ye L, Chen J, Ma L
Bioconjugate chemistry 2023 Aug 16;34(8):1498-1507
Bioconjugate chemistry 2023 Aug 16;34(8):1498-1507
Exosomal miR-205-5p enhances angiogenesis and nasopharyngeal carcinoma metastasis by targeting desmocollin-2.
Yang W, Tan S, Yang L, Chen X, Yang R, Oyang L, Lin J, Xia L, Wu N, Han Y, Tang Y, Su M, Luo X, Yang Y, Huang L, Hu Z, Tao Y, Liu L, Jin Y, Wang H, Liao Q, Zhou Y
Molecular therapy oncolytics 2022 Mar 17;24:612-623
Molecular therapy oncolytics 2022 Mar 17;24:612-623
Environmental cadmium impairs blood-testis barrier via activating HRI-responsive mitochondrial stress in mice.
Zhou GX, Liu WB, Dai LM, Zhu HL, Xiong YW, Li DX, Xu DX, Wang H
The Science of the total environment 2022 Mar 1;810:152247
The Science of the total environment 2022 Mar 1;810:152247
Mapping of truncated O-glycans in cancers of epithelial and non-epithelial origin.
Rømer TB, Aasted MKM, Dabelsteen S, Groen A, Schnabel J, Tan E, Pedersen JW, Haue AD, Wandall HH
British journal of cancer 2021 Oct;125(9):1239-1250
British journal of cancer 2021 Oct;125(9):1239-1250
Essential Functions of Glycans in Human Epithelia Dissected by a CRISPR-Cas9-Engineered Human Organotypic Skin Model.
Dabelsteen S, Pallesen EMH, Marinova IN, Nielsen MI, Adamopoulou M, Rømer TB, Levann A, Andersen MM, Ye Z, Thein D, Bennett EP, Büll C, Moons SJ, Boltje T, Clausen H, Vakhrushev SY, Bagdonaite I, Wandall HH
Developmental cell 2020 Sep 14;54(5):669-684.e7
Developmental cell 2020 Sep 14;54(5):669-684.e7
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Supportive validation
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- The Desmocollin 2 antibody from Proteintech is a rabbit polyclonal antibody to a recombinant protein of human Desmocollin 2. This antibody recognizes human antigen. The Desmocollin 2 antibody has been validated for the following applications: ELISA, IHC analysis.
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- Immunohistochemistry of paraffin-embedded human oesophagus tissue slide using 13876-1-AP( DSC2 Antibody) at dilution of 1:50 (under 10x lens)
- Other comments
- IHC
