20356-1-AP

antibody from Proteintech Group

Targeting: TRIM2 CMT2R, KIAA0517, RNF86

Western blot (Supportive data in Antibodypedia)

ELISA (Data presented on provider website)

Immunocytochemistry (Supportive data in Antibodypedia)

Immunoprecipitation (Data presented on provider website)

Immunohistochemistry (Data presented on provider website)

Antibody Data

Product number

20356-1-AP

Provider

Proteintech Group

Proper citation

Proteintech Cat#20356-1-AP, RRID:AB_10734319

Product name

TRIM2 antibody

Antibody type

Polyclonal

Description

KD/KO validated TRIM2 antibody (Cat. #20356-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse, rat and has been validated for the following applications: IF, IHC, IP, WB,ELISA.

Reactivity

Human, Mouse, Rat

Host

Rabbit

Conjugate

Unconjugated

Isotype

IgG

Vial size

20ul, 150ul

References

Submitted references

OSMR coordinates a self-perpetuating circuit linking chemoresistance and neutrophil-driven immunosuppression in gastric cancer.

Wei D, Chen J, Bai F, Li D, Liu J, Dou H, Lei Y, Zhang Y, Zhang B, Pang Y, Cao C, Yang T, Han J, Cao T
Neoplasia (New York, N.Y.) 2026 Mar;73:101279

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YTHDF3-TRIM2-P53 axis promotes malignant progression in uveal melanoma (UVM).

Li H, Chen Y, Chen W, Li D, Hao R, Zhang W
Cellular signalling 2026 Mar;139:112316

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Integrated multi-omics analysis and functional validation reveal the role of TRIM2 as a potential novel biomarker in breast cancer.

Deng R, Ren Y, Hu K, Zhang Y, Xu Y, Zhang Q, Li Y, Huang X, Zhang F
Breast cancer research : BCR 2026 Mar 31;28(1)

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TRIM2 promotes metabolic adaptation to glutamine deprivation via enhancement of CPT1A activity.

Liao K, Liu K, Wang Z, Zhao K, Mei Y
The FEBS journal 2025 Jan;292(2):275-293

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TRIM2 inhibits apoptosis by ubiquitinating BNIP3 to protect the intestine against ischemia-reperfusion injury in mice.

Nie J, Mei C, Wei A, Wang Y, Fan C, Huang Y, Jiang M, Che H, Chen T, Tian J, Li Y, Huang X, Zhang X
Communications biology 2025 Aug 29;8(1):1308

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E3 ubiquitin ligase TRIM2 identified as a novel suppressor of CYP11B2 and aldosterone production.

Chen L, Hu X, Wang G, Yu F, Dai Z, Jian X, Li Y, Xiang W, Meng Z
Cellular and molecular life sciences : CMLS 2024 Dec 27;82(1):27

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Stress-induced epinephrine promotes epithelial-to-mesenchymal transition and stemness of CRC through the CEBPB/TRIM2/P53 axis.

Zhou Z, Shu Y, Bao H, Han S, Liu Z, Zhao N, Yuan W, Jian C, Shu X
Journal of translational medicine 2022 Jun 7;20(1):262

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Divergent self-association properties of paralogous proteins TRIM2 and TRIM3 regulate their E3 ligase activity.

Esposito D, Dudley-Fraser J, Garza-Garcia A, Rittinger K
Nature communications 2022 Dec 8;13(1):7583

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TRIM2 directly deubiquitinates and stabilizes Snail1 protein, mediating proliferation and metastasis of lung adenocarcinoma.

Lin Z, Lin X, Zhu L, Huang J, Huang Y
Cancer cell international 2020;20:228

Western blot

Supportive validation

Submitted by

Proteintech Group (provider)

Main image

Experimental details

mouse small intestine tissue were subjected to SDS PAGE followed by western blot with 20356-1-AP(TRIM2 antibody) at dilution of 1:500

Sample type

tissue

Immunocytochemistry

Supportive validation

Submitted by

Proteintech Group (provider)

Main image

Experimental details

Immunofluorescent analysis of Hela cells, using TRIM2 antibody 20356-1-AP at 1:25 dilution and Rhodamine-labeled goat anti-rabbit IgG (red).

Sample type

cell line