BS9253

antibody from Bioworld Technology, Inc

Targeting: IKZF4 Eos, ZNFN1A4

Western blot (Data presented on provider website)

Antibody Data

Product number

BS9253

Provider

Bioworld Technology, Inc

Product name

Eos (R507) polyclonal antibody

Antibody type

Polyclonal

Antigen

Synthetic peptide, corresponding to amino acids 468-516 of Human Eos.

Description

Members of the Ikaros family contain zinc-finger domains that are involved in DNA-binding and in the formation of homodimers and heterodimers between Ikaros family members. Eos, also known as zinc finger protein Ikaros 4, is a 585 amino acid transcriptional repressor. Localized to the nucleus, Eos may play a role in the development of the central and peripheral nervous systems. Eos self-associates, forms heterodimers with Ikaros family members and interacts with CtBP2, PU.1 and MITF to repress transcription of cathepsin K and TRAP promoters. Eos is expressed at low levels in kidney, thymus, liver and heart, and at high levels in skeletal muscle.

Reactivity

Human, Mouse, Rat

Host

Rabbit

Isotype

IgG

Vial size

100ul

Concentration

1 mg/ml

Storage

Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.