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- Antigen structure
- References [14]
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- Western blot [1]
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- Product number
- 22378-1-AP - Provider product page
- Provider
- Proteintech Group
- Product name
- PPARGC1B antibody
- Antibody type
- Polyclonal
- Description
- KD/KO validated PPARGC1B antibody (Cat. #22378-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse and has been validated for the following applications: WB, ELISA.
- Reactivity
- Human, Mouse
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references miR-484 mediates oxidative stress-induced ovarian dysfunction and promotes granulosa cell apoptosis via SESN2 downregulation.
PGC1α Degradation Suppresses Mitochondrial Biogenesis to Confer Radiation Resistance in Glioma.
Metabolism-Based Molecular Subtyping Endows Effective Ketogenic Therapy in p53-Mutant Colon Cancer.
Muscle satellite cells are impaired in type 2 diabetic mice by elevated extracellular adenosine.
Interactions between dietary carbohydrate and thiamine: implications on the growth performance and intestinal mitochondrial biogenesis and function of Megalobrama amblycephala.
PGC-1β modulates catabolism and fiber atrophy in the fasting-response of specific skeletal muscle beds.
Andrographolide prevents bone loss via targeting estrogen-related receptor-α-regulated metabolic adaption of osteoclastogenesis.
Mitophagy receptor FUNDC1 is regulated by PGC-1α/NRF1 to fine tune mitochondrial homeostasis.
Carbonyl cyanide 3-chlorophenylhydrazone induced the imbalance of mitochondrial homeostasis in the liver of Megalobrama amblycephala: A dynamic study.
Mitochondrial metabolism is inhibited by the HIF1α-MYC-PGC-1β axis in BRAF V600E thyroid cancer.
miR-25 modulates triacylglycerol and lipid accumulation in goat mammary epithelial cells by repressing PGC-1beta.
Benfotiamine, a Lipid-Soluble Analog of Vitamin B(1), Improves the Mitochondrial Biogenesis and Function in Blunt Snout Bream (Megalobrama amblycephala) Fed High-Carbohydrate Diets by Promoting the AMPK/PGC-1β/NRF-1 Axis.
Dietary leucine supplementation alters energy metabolism and induces slow-to-fast transitions in longissimus dorsi muscle of weanling piglets.
Hypolipidemic effect of oleanolic acid is mediated by the miR-98-5p/PGC-1β axis in high-fat diet-induced hyperlipidemic mice.
Wang X, Yang J, Li H, Mu H, Zeng L, Cai S, Su P, Li H, Zhang L, Xiang W
Redox biology 2023 Jun;62:102684
Redox biology 2023 Jun;62:102684
PGC1α Degradation Suppresses Mitochondrial Biogenesis to Confer Radiation Resistance in Glioma.
Zhao M, Li Y, Lu C, Ding F, Xu M, Ge X, Li M, Wang Z, Yin J, Zhang J, Wang X, Ge Z, Xiao H, Xiao Y, Liu H, Liu W, Cao Y, Wang Q, You Y, Wang X, Yang K, Shi Z, Qian X
Cancer research 2023 Apr 4;83(7):1094-1110
Cancer research 2023 Apr 4;83(7):1094-1110
Metabolism-Based Molecular Subtyping Endows Effective Ketogenic Therapy in p53-Mutant Colon Cancer.
Tang M, Xu H, Huang H, Kuang H, Wang C, Li Q, Zhang X, Ge Y, Song M, Zhang X, Wang Z, Ma C, Kang J, Zhang W, Wang Y, Zhang B, Zhang X, Chen Y, Cong M, Melino G, Wang X, Zhou F, Sun Q, Shi H
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2022 Oct;9(29):e2201992
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2022 Oct;9(29):e2201992
Muscle satellite cells are impaired in type 2 diabetic mice by elevated extracellular adenosine.
Han L, Wang G, Zhou S, Situ C, He Z, Li Y, Qiu Y, Huang Y, Xu A, Ong MTY, Wang H, Zhang J, Wu Z
Cell reports 2022 May 31;39(9):110884
Cell reports 2022 May 31;39(9):110884
Interactions between dietary carbohydrate and thiamine: implications on the growth performance and intestinal mitochondrial biogenesis and function of Megalobrama amblycephala.
Xu C, Li YY, Brown PB, Liu WB, Gao LL, Ding ZR, Li XF, Xie DZ
The British journal of nutrition 2022 Feb 14;127(3):321-334
The British journal of nutrition 2022 Feb 14;127(3):321-334
PGC-1β modulates catabolism and fiber atrophy in the fasting-response of specific skeletal muscle beds.
Schmid S, Heim-Kupr B, Pérez-Schindler J, Mansingh S, Beer M, Mittal N, Ehrenfeuchter N, Handschin C
Molecular metabolism 2022 Dec;66:101643
Molecular metabolism 2022 Dec;66:101643
Andrographolide prevents bone loss via targeting estrogen-related receptor-α-regulated metabolic adaption of osteoclastogenesis.
Huang T, Fu X, Wang N, Yang M, Zhang M, Wang B, Chen T, Majaz S, Wang H, Wong CW, Liu J, Guan M
British journal of pharmacology 2021 Nov;178(21):4352-4367
British journal of pharmacology 2021 Nov;178(21):4352-4367
Mitophagy receptor FUNDC1 is regulated by PGC-1α/NRF1 to fine tune mitochondrial homeostasis.
Liu L, Li Y, Wang J, Zhang D, Wu H, Li W, Wei H, Ta N, Fan Y, Liu Y, Wang X, Wang J, Pan X, Liao X, Zhu Y, Chen Q
EMBO reports 2021 Mar 3;22(3):e50629
EMBO reports 2021 Mar 3;22(3):e50629
Carbonyl cyanide 3-chlorophenylhydrazone induced the imbalance of mitochondrial homeostasis in the liver of Megalobrama amblycephala: A dynamic study.
Zhang L, Zheng XC, Huang YY, Ge YP, Sun M, Chen WL, Liu WB, Li XF
Comparative biochemistry and physiology. Toxicology & pharmacology : CBP 2021 Jun;244:109003
Comparative biochemistry and physiology. Toxicology & pharmacology : CBP 2021 Jun;244:109003
Mitochondrial metabolism is inhibited by the HIF1α-MYC-PGC-1β axis in BRAF V600E thyroid cancer.
Gao Y, Yang F, Yang XA, Zhang L, Yu H, Cheng X, Xu S, Pan J, Wang K, Li P
The FEBS journal 2019 Apr;286(7):1420-1436
The FEBS journal 2019 Apr;286(7):1420-1436
miR-25 modulates triacylglycerol and lipid accumulation in goat mammary epithelial cells by repressing PGC-1beta.
Ma L, Qiu H, Chen Z, Li L, Zeng Y, Luo J, Gou D
Journal of animal science and biotechnology 2018;9:48
Journal of animal science and biotechnology 2018;9:48
Benfotiamine, a Lipid-Soluble Analog of Vitamin B(1), Improves the Mitochondrial Biogenesis and Function in Blunt Snout Bream (Megalobrama amblycephala) Fed High-Carbohydrate Diets by Promoting the AMPK/PGC-1β/NRF-1 Axis.
Xu C, Liu WB, Zhang DD, Shi HJ, Zhang L, Li XF
Frontiers in physiology 2018;9:1079
Frontiers in physiology 2018;9:1079
Dietary leucine supplementation alters energy metabolism and induces slow-to-fast transitions in longissimus dorsi muscle of weanling piglets.
Fan Q, Long B, Yan G, Wang Z, Shi M, Bao X, Hu J, Li X, Chen C, Zheng Z, Yan X
The British journal of nutrition 2017 May;117(9):1222-1234
The British journal of nutrition 2017 May;117(9):1222-1234
Hypolipidemic effect of oleanolic acid is mediated by the miR-98-5p/PGC-1β axis in high-fat diet-induced hyperlipidemic mice.
Chen S, Wen X, Zhang W, Wang C, Liu J, Liu C
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2017 Mar;31(3):1085-1096
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2017 Mar;31(3):1085-1096
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Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- mouse liver tissue were subjected to SDS PAGE followed by western blot with 22378-1-AP( PPARGC1B Antibody) at dilution of 1:300
- Other comments
- WB
