Antibody data
- Antibody Data
- Antigen structure
- References [7]
- Comments [0]
- Validations
- Western blot [1]
- Immunohistochemistry [1]
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Validation data
Reference
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- Product number
- 12211-1-AP - Provider product page
- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#12211-1-AP, RRID:AB_2084233
- Product name
- CPOX antibody
- Antibody type
- Polyclonal
- Description
- KD/KO validated CPOX antibody (Cat. #12211-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse, rat and has been validated for the following applications: IHC, IP, WB,ELISA.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references Heme Biosynthesis Factors and 5-ALA Induced Fluorescence: Analysis of mRNA and Protein Expression in Fluorescing and Non-fluorescing Gliomas.
The mitochondrial carrier SFXN1 is critical for complex III integrity and cellular metabolism.
Parkin-independent mitophagy via Drp1-mediated outer membrane severing and inner membrane ubiquitination.
Cystathionine-γ-lyase (CSE) deficiency increases erythropoiesis and promotes mitochondrial electron transport via the upregulation of coproporphyrinogen III oxidase and consequent stimulation of heme biosynthesis.
Protoporphyrinogen oxidase is involved in the fluorescence intensity of 5-aminolevulinic acid-mediated laser-based photodynamic endoscopic diagnosis for early gastric cancer.
Expression of coproporphyrinogen oxidase is associated with detection of upper gastrointestinal carcinomas by 5-aminolevulinic acid-mediated photodynamic diagnosis.
Enhanced expression of coproporphyrinogen oxidase in malignant brain tumors: CPOX expression and 5-ALA-induced fluorescence.
Mischkulnig M, Roetzer-Pejrimovsky T, Lötsch-Gojo D, Kastner N, Bruckner K, Prihoda R, Lang A, Martinez-Moreno M, Furtner J, Berghoff A, Woehrer A, Berger W, Widhalm G, Kiesel B
Frontiers in medicine 2022;9:907442
Frontiers in medicine 2022;9:907442
The mitochondrial carrier SFXN1 is critical for complex III integrity and cellular metabolism.
Acoba MG, Alpergin ESS, Renuse S, Fernández-Del-Río L, Lu YW, Khalimonchuk O, Clarke CF, Pandey A, Wolfgang MJ, Claypool SM
Cell reports 2021 Mar 16;34(11):108869
Cell reports 2021 Mar 16;34(11):108869
Parkin-independent mitophagy via Drp1-mediated outer membrane severing and inner membrane ubiquitination.
Oshima Y, Cartier E, Boyman L, Verhoeven N, Polster BM, Huang W, Kane M, Lederer WJ, Karbowski M
The Journal of cell biology 2021 Jun 7;220(6)
The Journal of cell biology 2021 Jun 7;220(6)
Cystathionine-γ-lyase (CSE) deficiency increases erythropoiesis and promotes mitochondrial electron transport via the upregulation of coproporphyrinogen III oxidase and consequent stimulation of heme biosynthesis.
Módis K, Ramanujam VS, Govar AA, Lopez E, Anderson KE, Wang R, Szabo C
Biochemical pharmacology 2019 Nov;169:113604
Biochemical pharmacology 2019 Nov;169:113604
Protoporphyrinogen oxidase is involved in the fluorescence intensity of 5-aminolevulinic acid-mediated laser-based photodynamic endoscopic diagnosis for early gastric cancer.
Kurumi H, Kanda T, Kawaguchi K, Yashima K, Koda H, Ogihara K, Matsushima K, Nakao K, Saito H, Fujiwara Y, Osaki M, Okada F, Isomoto H
Photodiagnosis and photodynamic therapy 2018 Jun;22:79-85
Photodiagnosis and photodynamic therapy 2018 Jun;22:79-85
Expression of coproporphyrinogen oxidase is associated with detection of upper gastrointestinal carcinomas by 5-aminolevulinic acid-mediated photodynamic diagnosis.
Ogihara K, Isomoto H, Kurumi H, Kanda T, Hashisako M, Tabata K, Ishii H, Ohnita K, Yamaguchi N, Akazawa Y, Matsushima K, Takeshima F, Kunizaki M, Hidaka S, Nanashima A, Fukuoka J, Nagayasu T, Nakao K
Photodiagnosis and photodynamic therapy 2017 Sep;19:15-21
Photodiagnosis and photodynamic therapy 2017 Sep;19:15-21
Enhanced expression of coproporphyrinogen oxidase in malignant brain tumors: CPOX expression and 5-ALA-induced fluorescence.
Takahashi K, Ikeda N, Nonoguchi N, Kajimoto Y, Miyatake S, Hagiya Y, Ogura S, Nakagawa H, Ishikawa T, Kuroiwa T
Neuro-oncology 2011 Nov;13(11):1234-43
Neuro-oncology 2011 Nov;13(11):1234-43
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Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- human liver tissue were subjected to SDS PAGE followed by western blot with 12211-1-AP(CPOX antibody) at dilution of 1:500
- Sample type
- tissue
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- The Coproporphyrinogen oxidase antibody from Proteintech is a rabbit polyclonal antibody to a recombinant protein of human Coproporphyrinogen oxidase. This antibody recognizes human,mouse,rat antigen. The Coproporphyrinogen oxidase antibody has been validated for the following applications: ELISA, WB, IHC analysis.