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- Antibody Data
- Antigen structure
- References [8]
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- Validations
- Western blot [1]
- Immunohistochemistry [1]
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- Product number
- 16082-1-AP - Provider product page
- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#16082-1-AP, RRID:AB_2159996
- Product name
- PCIF1 antibody
- Antibody type
- Polyclonal
- Description
- PCIF1 antibody (Cat. #16082-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse and has been validated for the following applications: IHC, WB,ELISA.
- Reactivity
- Human, Mouse
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references The WW domain presents a promising target for the development of PCIF1 agonists in the treatment of glioma.
The pseudorabies virus UL13 protein kinase triggers phosphorylation of the RNA demethylase FTO, which is associated with FTO-dependent suppression of interferon-stimulated gene expression.
PCIF1 drives oesophageal squamous cell carcinoma progression via m6Am-mediated suppression of MTF2 translation.
PCIF1-mediated deposition of 5'-cap N(6),2'-O-dimethyladenosine in ACE2 and TMPRSS2 mRNA regulates susceptibility to SARS-CoV-2 infection.
Role of PCIF1-mediated 5'-cap N6-methyladeonsine mRNA methylation in colorectal cancer and anti-PD-1 immunotherapy.
RNA Pol II preferentially regulates ribosomal protein expression by trapping disassociated subunits.
Alphaherpesvirus US3 protein-mediated inhibition of the m6A mRNA methyltransferase complex.
HIV reprograms host m(6)Am RNA methylome by viral Vpr protein-mediated degradation of PCIF1.
Yin J, Liu G, Zhou Y, Zhou J, Guo M, Hu Z, Musunuru PP, Yu R, Meng Q, Gao S
NPJ precision oncology 2025 Oct 23;9(1):329
NPJ precision oncology 2025 Oct 23;9(1):329
The pseudorabies virus UL13 protein kinase triggers phosphorylation of the RNA demethylase FTO, which is associated with FTO-dependent suppression of interferon-stimulated gene expression.
Verhamme R, Jansens RJJ, Liu J, Van Raemdonck F, Van Waesberghe C, Nicholson L, Jaffrey SR, Favoreel HW
Journal of virology 2025 Feb 25;99(2):e0201924
Journal of virology 2025 Feb 25;99(2):e0201924
PCIF1 drives oesophageal squamous cell carcinoma progression via m6Am-mediated suppression of MTF2 translation.
Li K, Yi Y, Ling R, Zhang C, Zhang Z, Wang Y, Wang G, Chen J, Cheng M, Chen S
Clinical and translational medicine 2025 Apr;15(4):e70286
Clinical and translational medicine 2025 Apr;15(4):e70286
PCIF1-mediated deposition of 5'-cap N(6),2'-O-dimethyladenosine in ACE2 and TMPRSS2 mRNA regulates susceptibility to SARS-CoV-2 infection.
Wang L, Wang S, Wu L, Li W, Bray W, Clark AE, Gonzalez GM, Wang Y, Carlin AF, Rana TM
Proceedings of the National Academy of Sciences of the United States of America 2023 Jan 31;120(5):e2210361120
Proceedings of the National Academy of Sciences of the United States of America 2023 Jan 31;120(5):e2210361120
Role of PCIF1-mediated 5'-cap N6-methyladeonsine mRNA methylation in colorectal cancer and anti-PD-1 immunotherapy.
Wang L, Wu L, Zhu Z, Zhang Q, Li W, Gonzalez GM, Wang Y, Rana TM
The EMBO journal 2023 Jan 16;42(2):e111673
The EMBO journal 2023 Jan 16;42(2):e111673
RNA Pol II preferentially regulates ribosomal protein expression by trapping disassociated subunits.
Li Y, Huang J, Bao L, Zhu J, Duan W, Zheng H, Wang H, Jiang Y, Liu W, Zhang M, Yu Y, Yi C, Ji X
Molecular cell 2023 Apr 20;83(8):1280-1297.e11
Molecular cell 2023 Apr 20;83(8):1280-1297.e11
Alphaherpesvirus US3 protein-mediated inhibition of the m6A mRNA methyltransferase complex.
Jansens RJJ, Verhamme R, Mirza AH, Olarerin-George A, Van Waesberghe C, Jaffrey SR, Favoreel HW
Cell reports 2022 Jul 19;40(3):111107
Cell reports 2022 Jul 19;40(3):111107
HIV reprograms host m(6)Am RNA methylome by viral Vpr protein-mediated degradation of PCIF1.
Zhang Q, Kang Y, Wang S, Gonzalez GM, Li W, Hui H, Wang Y, Rana TM
Nature communications 2021 Sep 20;12(1):5543
Nature communications 2021 Sep 20;12(1):5543
No comments: Submit comment
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- Jurkat cells were subjected to SDS PAGE followed by western blot with 16082-1-AP(PCIF1 antibody) at dilution of 1:800
- Sample type
- cell line
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- The PCIF1 antibody from Proteintech is a rabbit polyclonal antibody to a recombinant protein of human PCIF1. This antibody recognizes human, mouse antigen. The PCIF1 antibody has been validated for the following applications: ELISA, WB, IHC analysis.
