Antibody data
- Antibody Data
- Antigen structure
- References [0]
- Comments [0]
- Validations [0]
Submit
Validation data
Reference
Comment
Report error
- Product number
- CABT-B9324 - Provider product page
- Provider
- Creative Diagnostics
- Product name
- Mouse anti-Rat Striatin monoclonal antibody, clone 7
- Antibody type
- Monoclonal
- Description
- Signal transmission between neurons is regulated by the Ca2+-dependent release of neurotransmitters at the synapse. Striatin is a protein identified in the synaptosomal fraction of rat brain. Reports of sequence homology searches have shown that striatin belongs to a family of proteins with the repeated WD motif (the ÉÇ-transducin repeat or the WD-40 repeat) found in regulatory proteins. Striatin also binds calmodulin in a Ca2+-dependent manner. Immunolocalization and mRNA expression found striatin in the central nervous system, particularly enriched in neurons of the striatum and motor neurons. Furthermore, subcellular localization studies indicated that Striatin is tightly associated with the plasma membrane. Thus, striatin may play an important role in the Ca2+-dependent events occurring at the synapse.
- Reactivity
- Human, Mouse, Rat, Canine
- Host
- Mouse
- Conjugate
- Unconjugated
- Isotype
- IgG
- Antibody clone number
- 7
- Vial size
- 50 _g
- Concentration
- 250 Ã×g/ml
- Storage
- Store undiluted at -20°C.
No comments: Submit comment
No validations: Submit validation data