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- Product number
- 10594-1-AP - Provider product page
- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#10594-1-AP, RRID:AB_2252194
- Product name
- PEX14 antibody
- Antibody type
- Polyclonal
- Description
- PEX14 antibody (Cat. #10594-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse, rat, monkey and has been validated for the following applications: FC, IF, IHC, IP, WB, ELISA.
- Reactivity
- Human, Mouse, Rat, Simian
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references Unveiling the roles of PEX16 in female reproductive capacity and lifespan of brown planthopper, Nilaparvata lugens (Stål), in relation to PEX14.
Organelles harbour pH gradients.
Aging impairs peroxisome biogenesis in human B cells.
Modeling the cell biology of PEX11β deficiency during human neurogenesis.
MAVS oligomerization drives a faster and more efficient antiviral signaling activation at peroxisomes compared to mitochondria.
PEX14 condensates recruit receptor and cargo pairs for peroxisomal protein import.
Lactobacillus acidophilus promotes cognitive function recovery via regulating microglial peroxisomal function in cerebral ischemia.
SIRT5-mediated desuccinylation of the porcine deltacoronavirus M protein drives pexophagy to enhance viral proliferation.
Cytoskeleton regulates lipid droplet fusion and lipid storage by controlling lipid droplet movement.
Peroxisomes are critical for a unique metabolic demand and survival of alveolar macrophages.
Blebbisomes are large, organelle-rich extracellular vesicles with cell-like properties.
Macrophage peroxisomes guide alveolar regeneration and limit SARS-CoV-2 tissue sequelae.
Peroxisomal ether-glycerophospholipid synthesis is dysregulated after TBI.
Legionella effector LpPIP recruits protein phosphatase 1 to the mitochondria to induce dephosphorylation of outer membrane proteins.
FAF2 is a bifunctional regulator of peroxisomal homeostasis and saturated lipid responses.
Drug-induced metabolic remodeling of immune cell repertoire generates an effective broad-range antimicrobial effect.
Ubiquitin ligase MARCH5 controls the formation of mitochondria-derived pre-peroxisomes.
Genomewide Screen Identifies Peroxisomal Role in APOL1 Podocytopathy.
Organelles harbour pH gradients.
Cholesterol ensures ciliary polycystin-2 localization to prevent polycystic kidney disease.
Using chanarin-dorfman syndrome patient fibroblasts to explore disease mechanisms and new treatment avenues.
Fluorescent fatty acid conjugates for live cell imaging of peroxisomes.
The HRI branch of the integrated stress response selectively triggers mitophagy.
EHHADH deficiency regulates pexophagy and accelerates tubulointerstitial injury in diabetic kidney disease.
Temperature-dependent intracellular crystallization of firefly luciferase in mammalian cells is suppressed by D-luciferin and stabilizing inhibitors.
Allosteric control of dynamin-related protein 1 through a disordered C-terminal Short Linear Motif.
Proteomic analysis reveals that cigarette smoke exposure diminishes ovarian reserve in mice by disrupting the CREB1-mediated ovarian granulosa cell proliferation-apoptosis balance.
Abnormal redox balance at membrane contact sites causes axonopathy in GDAP1-related Charcot-Marie-Tooth disease.
Overexpression of PEX14 results in mistargeting to mitochondria, accompanied by organelle fragmentation and clustering in human embryonic kidney cells.
Super-Resolution Imaging of Peroxisomal Proteins Using STED Nanoscopy.
Assessing Peroxisomal Protein Interaction by Immunoprecipitation.
Proximity-Ligation Assay to Detect Peroxisome-Organelle Interaction.
Hepatitis C virus alters the morphology and function of peroxisomes.
A Heterozygous Mutation in MFF Associated with a Mild Mitochondrial Phenotype.
Prosaposin maintains lipid homeostasis in dopamine neurons and counteracts experimental parkinsonism in rodents.
Transmembrane protein 135 regulates lipid homeostasis through its role in peroxisomal DHA metabolism.
TTBK2 mutations associated with spinocerebellar ataxia type 11 disrupt peroxisome dynamics and ciliary localization of SHH signaling proteins.
Germ cell-specific deletion of Pex3 reveals essential roles of PEX3-dependent peroxisomes in spermiogenesis.
The Key Role of Peroxisomes in Follicular Growth, Oocyte Maturation, Ovulation, and Steroid Biosynthesis.
TMEM63C mutations cause mitochondrial morphology defects and underlie hereditary spastic paraplegia.
ATP13A1 prevents ERAD of folding-competent mislocalized and misoriented proteins.
An AMPKα2-specific phospho-switch controls lysosomal targeting for activation.
Mitochondrial remodeling and ischemic protection by G protein-coupled receptor 35 agonists.
Proteomic Identification of Coxiella burnetii Effector Proteins Targeted to the Host Cell Mitochondria During Infection.
Peroxisomes contribute to intracellular calcium dynamics in cardiomyocytes and non-excitable cells.
HIV-1 Env induces pexophagy and an oxidative stress leading to uninfected CD4(+) T cell death.
Labeling and measuring stressed mitochondria using a PINK1-based ratiometric fluorescent sensor.
Peroxisomal-derived ether phospholipids link nucleotides to respirasome assembly.
Limited survival and impaired hepatic fasting metabolism in mice with constitutive Rag GTPase signaling.
USP19 promotes hypoxia-induced mitochondrial division via FUNDC1 at ER-mitochondria contact sites.
Establishment and analysis of conditional Rab1- and Rab5-knockout cells using the auxin-inducible degron system.
An engineered transcriptional reporter of protein localization identifies regulators of mitochondrial and ER membrane protein trafficking in high-throughput CRISPRi screens.
A Network of Macrophages Supports Mitochondrial Homeostasis in the Heart.
Drp1 Tubulates the ER in a GTPase-Independent Manner.
Golgi-derived PI(4)P-containing vesicles drive late steps of mitochondrial division.
Insufficiency of ciliary cholesterol in hereditary Zellweger syndrome.
A cross-talk between epithelium and endothelium mediates human alveolar-capillary injury during SARS-CoV-2 infection.
Peroxisomes control mitochondrial dynamics and the mitochondrion-dependent apoptosis pathway.
Peroxisome turnover and diurnal modulation of antioxidant activity in retinal pigment epithelia utilizes microtubule-associated protein 1 light chain 3B (LC3B).
F-actin patches associated with glutamatergic synapses control positioning of dendritic lysosomes.
In Vivo Deletion of β-Cell Drp1 Impairs Insulin Secretion Without Affecting Islet Oxygen Consumption.
Super-resolution imaging reveals the sub-diffraction phenotype of Zellweger Syndrome ghosts and wild-type peroxisomes.
Autophagy defects and related genetic variations in renal cell carcinoma with eosinophilic cytoplasmic inclusions.
Isolation of Peroxisomes from Mouse Brain Using a Continuous Nycodenz Gradient: A Comparison to the Isolation of Liver and Kidney Peroxisomes.
Dysferlin mediates membrane tubulation and links T-tubule biogenesis to muscular dystrophy.
Novel regulatory roles of Mff and Drp1 in E3 ubiquitin ligase MARCH5-dependent degradation of MiD49 and Mcl1 and control of mitochondrial dynamics.
The functional readthrough extension of malate dehydrogenase reveals a modification of the genetic code.
Spectrum of PEX1 and PEX6 variants in Heimler syndrome.
A Dendritic Golgi Satellite between ERGIC and Retromer.
Titration of mitochondrial fusion rescues Mff-deficient cardiomyopathy.
Conserved targeting information in mammalian and fungal peroxisomal tail-anchored proteins.
Peroxisomal lactate dehydrogenase is generated by translational readthrough in mammals.
Hif-2α promotes degradation of mammalian peroxisomes by selective autophagy.
Peroxisomes are juxtaposed to strategic sites on mitochondria.
Functional analysis of PEX13 mutation in a Zellweger syndrome spectrum patient reveals novel homooligomerization of PEX13 and its role in human peroxisome biogenesis.
Charcot-Marie-Tooth disease-associated mutants of GDAP1 dissociate its roles in peroxisomal and mitochondrial fission.
Peroxisome deficiency-induced ER stress and SREBP-2 pathway activation in the liver of newborn PEX2 knock-out mice.
Loss of ceramide synthase 3 causes lethal skin barrier disruption.
Lymphoblastoid cell lines for diagnosis of peroxisome biogenesis disorders.
The unusual extended C-terminal helix of the peroxisomal α/β-hydrolase Lpx1 is involved in dimer contacts but dispensable for dimerization.
A role for myelin-associated peroxisomes in maintaining paranodal loops and axonal integrity.
Typical cMRI pattern as diagnostic clue for D-bifunctional protein deficiency without apparent biochemical abnormalities in plasma.
Liu Y, Zhang Q, Mao Y, Qiu Z, Lin X
Pest management science 2026 Jan;82(1):500-510
Pest management science 2026 Jan;82(1):500-510
Organelles harbour pH gradients.
Lee S, Chakraborty S, Kim S, Ali A, Mitra K, Zajac M, Brown A, Pincus D, Krishnan Y
Research square 2026 Jan 20;
Research square 2026 Jan 20;
Aging impairs peroxisome biogenesis in human B cells.
Correia J, Roy PS, Holden KG, Kohut ML, Bai H
The journals of gerontology. Series A, Biological sciences and medical sciences 2026 Jan 12;81(2)
The journals of gerontology. Series A, Biological sciences and medical sciences 2026 Jan 12;81(2)
Modeling the cell biology of PEX11β deficiency during human neurogenesis.
Bodnya C, Theart RP, Gama V
bioRxiv : the preprint server for biology 2026 Feb 16;
bioRxiv : the preprint server for biology 2026 Feb 16;
MAVS oligomerization drives a faster and more efficient antiviral signaling activation at peroxisomes compared to mitochondria.
Ramos B, Sarabando J, Marques M, Kagan JC, Ribeiro D
The FEBS journal 2026 Apr;293(7):2086-2097
The FEBS journal 2026 Apr;293(7):2086-2097
PEX14 condensates recruit receptor and cargo pairs for peroxisomal protein import.
Wu J, Lv S, Xu P, Yue S, Zhuang M
Nature structural & molecular biology 2025 Sep;32(9):1644-1656
Nature structural & molecular biology 2025 Sep;32(9):1644-1656
Lactobacillus acidophilus promotes cognitive function recovery via regulating microglial peroxisomal function in cerebral ischemia.
Huang Y, Zhang X, Yu C, Liu Y, Kang H, Liu Y, Ni Y, Xia Y, Jiang Z, Chen J, Zhao K, Han L, Zou X, Wang J, Lei T, Gan C, Zhang H
Cell host & microbe 2025 Sep 10;33(9):1484-1501.e12
Cell host & microbe 2025 Sep 10;33(9):1484-1501.e12
SIRT5-mediated desuccinylation of the porcine deltacoronavirus M protein drives pexophagy to enhance viral proliferation.
Li Z, Tang W, Lai Y, Chen C, Fang P, Zhou Y, Fang L, Xiao S
PLoS pathogens 2025 May;21(5):e1013163
PLoS pathogens 2025 May;21(5):e1013163
Cytoskeleton regulates lipid droplet fusion and lipid storage by controlling lipid droplet movement.
Liang Y, Zhu Z, Lu Y, Ma C, Li J, Yu K, Wu J, Che X, Liu X, Huang X, Li P, Chen FJ
Biochimica et biophysica acta. Molecular and cell biology of lipids 2025 May;1870(4):159610
Biochimica et biophysica acta. Molecular and cell biology of lipids 2025 May;1870(4):159610
Peroxisomes are critical for a unique metabolic demand and survival of alveolar macrophages.
Matsushita M, Muri J, Berest I, Li F, Liu H, Corak B, Zamboni N, Buescher J, Othman A, Corrado M, Cupovic J, Werner S, Kovacs W, Kopf M
Cell reports 2025 May 27;44(5):115623
Cell reports 2025 May 27;44(5):115623
Blebbisomes are large, organelle-rich extracellular vesicles with cell-like properties.
Jeppesen DK, Sanchez ZC, Kelley NM, Hayes JB, Ambroise J, Koory EN, Krystofiak E, Taneja N, Zhang Q, Dungan MM, Perkins OL, Tyska MJ, Knapik EW, Dean KM, Doran AC, Coffey RJ, Burnette DT
Nature cell biology 2025 Mar;27(3):438-448
Nature cell biology 2025 Mar;27(3):438-448
Macrophage peroxisomes guide alveolar regeneration and limit SARS-CoV-2 tissue sequelae.
Wei X, Qian W, Narasimhan H, Chan T, Liu X, Arish M, Young S, Li C, Cheon IS, Yu Q, Almeida-Santos G, Zhao XY, Yeatts EV, Spear OJ, Yi M, Parimon T, Fang Y, Hahn YS, Bullock TNJ, Somerville LA, Kaplan MH, Sperling AI, Shim YM, Vassallo R, Chen P, Ewald SE, Roden AC, Que J, Jiang D, Sun J
Science (New York, N.Y.) 2025 Mar 7;387(6738):eadq2509
Science (New York, N.Y.) 2025 Mar 7;387(6738):eadq2509
Peroxisomal ether-glycerophospholipid synthesis is dysregulated after TBI.
Mehrabani-Tabari AA, Hegdekar N, Bustos S, Morel Y, Ji Y, Kachi SA, Pettyjohn-Robin O, Thapa S, Bhattiprolu M, Lipinski MM, Jones JW, Sarkar C
Journal of lipid research 2025 Jun;66(6):100821
Journal of lipid research 2025 Jun;66(6):100821
Legionella effector LpPIP recruits protein phosphatase 1 to the mitochondria to induce dephosphorylation of outer membrane proteins.
Yek KQ, Hodgson ER, Ang CS, Palmer CS, Frazier AE, Newton HJ, Stojanovski D
PLoS biology 2025 Jul;23(7):e3003261
PLoS biology 2025 Jul;23(7):e3003261
FAF2 is a bifunctional regulator of peroxisomal homeostasis and saturated lipid responses.
Kim C, Gabriel KR, Boone D, Brown MR, Oppenheimer K, Kost-Alimova M, Pablo JLB, Greka A
Science advances 2025 Jul 4;11(27):eadu9104
Science advances 2025 Jul 4;11(27):eadu9104
Drug-induced metabolic remodeling of immune cell repertoire generates an effective broad-range antimicrobial effect.
Prusty BK, Hollmann C, Park EC, Liu Z, Nourollahi F, Nikolayshvili G, Dietz J, Bašēns E, Vora M, Waghmare T, Li T, Imdahl F, Rongo C
Research square 2025 Jul 29;
Research square 2025 Jul 29;
Ubiquitin ligase MARCH5 controls the formation of mitochondria-derived pre-peroxisomes.
Zheng J, Chen J, Cao Z, Wu K, Wang J, Guo Y, Zhuang M
Developmental cell 2025 Jan 6;60(1):30-39.e3
Developmental cell 2025 Jan 6;60(1):30-39.e3
Genomewide Screen Identifies Peroxisomal Role in APOL1 Podocytopathy.
Kim J, Karel IZ, Song H, Dewalt M, Orwick S, Buelow DR, Lee K, Brodsky SV, Blissett A, Cocucci E, Baker SD, Lin PH, Pabla NS, Madhavan SM
medRxiv : the preprint server for health sciences 2025 Feb 18;
medRxiv : the preprint server for health sciences 2025 Feb 18;
Organelles harbour pH gradients.
Lee S, Chakraborty S, Kim S, Ali A, Mitra K, Zajac M, Brown A, Pincus D, Krishnan Y
bioRxiv : the preprint server for biology 2025 Dec 16;
bioRxiv : the preprint server for biology 2025 Dec 16;
Cholesterol ensures ciliary polycystin-2 localization to prevent polycystic kidney disease.
Itabashi T, Hosoba K, Morita T, Kimura S, Yamaoka K, Hirosawa M, Kobayashi D, Kishi H, Kume K, Itoh H, Kawakami H, Hashimoto K, Yamamoto T, Miyamoto T
Life science alliance 2025 Apr;8(4)
Life science alliance 2025 Apr;8(4)
Using chanarin-dorfman syndrome patient fibroblasts to explore disease mechanisms and new treatment avenues.
Angel M, Kleinberg Y, Newaz T, Li V, Zaid R, Oved K, Dorot O, Pichinuk E, Avitan-Hersh E, Saada A, Weiss K, Zaremberg V, Tal G, Zalckvar E
Orphanet journal of rare diseases 2025 Apr 24;20(1):195
Orphanet journal of rare diseases 2025 Apr 24;20(1):195
Fluorescent fatty acid conjugates for live cell imaging of peroxisomes.
Korotkova D, Borisyuk A, Guihur A, Bardyn M, Kuttler F, Reymond L, Schuhmacher M, Amen T
Nature communications 2024 May 21;15(1):4314
Nature communications 2024 May 21;15(1):4314
The HRI branch of the integrated stress response selectively triggers mitophagy.
Chakrabarty Y, Yang Z, Chen H, Chan DC
Molecular cell 2024 Mar 21;84(6):1090-1100.e6
Molecular cell 2024 Mar 21;84(6):1090-1100.e6
EHHADH deficiency regulates pexophagy and accelerates tubulointerstitial injury in diabetic kidney disease.
Kan S, Hou Q, Shi J, Zhang M, Xu F, Liu Z, Jiang S
Cell death discovery 2024 Jun 15;10(1):289
Cell death discovery 2024 Jun 15;10(1):289
Temperature-dependent intracellular crystallization of firefly luciferase in mammalian cells is suppressed by D-luciferin and stabilizing inhibitors.
Hasegawa H
Experimental cell research 2024 Jul 1;440(1):114131
Experimental cell research 2024 Jul 1;440(1):114131
Allosteric control of dynamin-related protein 1 through a disordered C-terminal Short Linear Motif.
Pérez-Jover I, Rochon K, Hu D, Mahajan M, Madan Mohan P, Santos-Pérez I, Ormaetxea Gisasola J, Martinez Galvez JM, Agirre J, Qi X, Mears JA, Shnyrova AV, Ramachandran R
Nature communications 2024 Jan 2;15(1):52
Nature communications 2024 Jan 2;15(1):52
Proteomic analysis reveals that cigarette smoke exposure diminishes ovarian reserve in mice by disrupting the CREB1-mediated ovarian granulosa cell proliferation-apoptosis balance.
Xu M, Li F, Xu X, Hu N, Miao J, Zhao Y, Ji S, Wang Y, Wang L
Ecotoxicology and environmental safety 2024 Feb;271:115989
Ecotoxicology and environmental safety 2024 Feb;271:115989
Abnormal redox balance at membrane contact sites causes axonopathy in GDAP1-related Charcot-Marie-Tooth disease.
Cantarero L, Roldán M, Rodríguez-Sanz M, Mathison AJ, Díaz-Osorio Y, Pijuan J, Frías M, Urrutia R, Hoenicka J, Palau F
Research square 2024 Dec 31;
Research square 2024 Dec 31;
Overexpression of PEX14 results in mistargeting to mitochondria, accompanied by organelle fragmentation and clustering in human embryonic kidney cells.
Jansen RLM, de Boer R, de Lange EMF, Koster J, Vlijm R, Waterham HR, van der Klei IJ
Biochimica et biophysica acta. Molecular cell research 2024 Aug;1871(6):119754
Biochimica et biophysica acta. Molecular cell research 2024 Aug;1871(6):119754
Super-Resolution Imaging of Peroxisomal Proteins Using STED Nanoscopy.
de Lange EMF, Vlijm R
Methods in molecular biology (Clifton, N.J.) 2023;2643:65-84
Methods in molecular biology (Clifton, N.J.) 2023;2643:65-84
Assessing Peroxisomal Protein Interaction by Immunoprecipitation.
Kors S, Schrader M
Methods in molecular biology (Clifton, N.J.) 2023;2643:345-357
Methods in molecular biology (Clifton, N.J.) 2023;2643:345-357
Proximity-Ligation Assay to Detect Peroxisome-Organelle Interaction.
Kamoshita M, Schrader M
Methods in molecular biology (Clifton, N.J.) 2023;2643:135-148
Methods in molecular biology (Clifton, N.J.) 2023;2643:135-148
Hepatitis C virus alters the morphology and function of peroxisomes.
Martin de Fourchambault E, Callens N, Saliou JM, Fourcot M, Delos O, Barois N, Thorel Q, Ramirez S, Bukh J, Cocquerel L, Bertrand-Michel J, Marot G, Sebti Y, Dubuisson J, Rouillé Y
Frontiers in microbiology 2023;14:1254728
Frontiers in microbiology 2023;14:1254728
A Heterozygous Mutation in MFF Associated with a Mild Mitochondrial Phenotype.
Murata D, Grunseich C, Iijima M, Chan D, Corse A, Hoke A, Schindler A, Sesaki H, Roda RH
Journal of neuromuscular diseases 2023;10(1):107-118
Journal of neuromuscular diseases 2023;10(1):107-118
Prosaposin maintains lipid homeostasis in dopamine neurons and counteracts experimental parkinsonism in rodents.
He Y, Kaya I, Shariatgorji R, Lundkvist J, Wahlberg LU, Nilsson A, Mamula D, Kehr J, Zareba-Paslawska J, Biverstål H, Chergui K, Zhang X, Andren PE, Svenningsson P
Nature communications 2023 Sep 19;14(1):5804
Nature communications 2023 Sep 19;14(1):5804
Transmembrane protein 135 regulates lipid homeostasis through its role in peroxisomal DHA metabolism.
Landowski M, Bhute VJ, Grindel S, Haugstad Z, Gyening YK, Tytanic M, Brush RS, Moyer LJ, Nelson DW, Davis CR, Yen CE, Ikeda S, Agbaga MP, Ikeda A
Communications biology 2023 Jan 4;6(1):8
Communications biology 2023 Jan 4;6(1):8
TTBK2 mutations associated with spinocerebellar ataxia type 11 disrupt peroxisome dynamics and ciliary localization of SHH signaling proteins.
Muñoz-Estrada J, Nguyen AV, Goetz SC
bioRxiv : the preprint server for biology 2023 Feb 1;
bioRxiv : the preprint server for biology 2023 Feb 1;
Germ cell-specific deletion of Pex3 reveals essential roles of PEX3-dependent peroxisomes in spermiogenesis.
Yao Y, Shi B, Zhang X, Wang X, Li S, Yao Y, Guo Y, Chen D, Wang B, Yuan Y, Sha J, Guo X
Journal of biomedical research 2023 Dec 8;38(1):24-36
Journal of biomedical research 2023 Dec 8;38(1):24-36
The Key Role of Peroxisomes in Follicular Growth, Oocyte Maturation, Ovulation, and Steroid Biosynthesis.
Wang S, Yang H, Fu Y, Teng X, Wang C, Xu W
Oxidative medicine and cellular longevity 2022;2022:7982344
Oxidative medicine and cellular longevity 2022;2022:7982344
TMEM63C mutations cause mitochondrial morphology defects and underlie hereditary spastic paraplegia.
Tábara LC, Al-Salmi F, Maroofian R, Al-Futaisi AM, Al-Murshedi F, Kennedy J, Day JO, Courtin T, Al-Khayat A, Galedari H, Mazaheri N, Protasoni M, Johnson M, Leslie JS, Salter CG, Rawlins LE, Fasham J, Al-Maawali A, Voutsina N, Charles P, Harrold L, Keren B, Kunji ERS, Vona B, Jelodar G, Sedaghat A, Shariati G, Houlden H, Crosby AH, Prudent J, Baple EL
Brain : a journal of neurology 2022 Sep 14;145(9):3095-3107
Brain : a journal of neurology 2022 Sep 14;145(9):3095-3107
ATP13A1 prevents ERAD of folding-competent mislocalized and misoriented proteins.
McKenna MJ, Adams BM, Chu V, Paulo JA, Shao S
Molecular cell 2022 Nov 17;82(22):4277-4289.e10
Molecular cell 2022 Nov 17;82(22):4277-4289.e10
An AMPKα2-specific phospho-switch controls lysosomal targeting for activation.
Morrison KR, Smiles WJ, Ling NXY, Hoque A, Shea G, Ngoei KRW, Yu D, Murray-Segal L, Scott JW, Galic S, Kemp BE, Petersen J, Oakhill JS
Cell reports 2022 Feb 15;38(7):110365
Cell reports 2022 Feb 15;38(7):110365
Mitochondrial remodeling and ischemic protection by G protein-coupled receptor 35 agonists.
Wyant GA, Yu W, Doulamis IP, Nomoto RS, Saeed MY, Duignan T, McCully JD, Kaelin WG Jr
Science (New York, N.Y.) 2022 Aug 5;377(6606):621-629
Science (New York, N.Y.) 2022 Aug 5;377(6606):621-629
Proteomic Identification of Coxiella burnetii Effector Proteins Targeted to the Host Cell Mitochondria During Infection.
Fielden LF, Scott NE, Palmer CS, Khoo CA, Newton HJ, Stojanovski D
Molecular & cellular proteomics : MCP 2021;20:100005
Molecular & cellular proteomics : MCP 2021;20:100005
Peroxisomes contribute to intracellular calcium dynamics in cardiomyocytes and non-excitable cells.
Sargsyan Y, Bickmeyer U, Gibhardt CS, Streckfuss-Bömeke K, Bogeski I, Thoms S
Life science alliance 2021 Sep;4(9)
Life science alliance 2021 Sep;4(9)
HIV-1 Env induces pexophagy and an oxidative stress leading to uninfected CD4(+) T cell death.
Daussy CF, Galais M, Pradel B, Robert-Hebmann V, Sagnier S, Pattingre S, Biard-Piechaczyk M, Espert L
Autophagy 2021 Sep;17(9):2465-2474
Autophagy 2021 Sep;17(9):2465-2474
Labeling and measuring stressed mitochondria using a PINK1-based ratiometric fluorescent sensor.
Uesugi R, Ishii S, Matsuura A, Itakura E
The Journal of biological chemistry 2021 Nov;297(5):101279
The Journal of biological chemistry 2021 Nov;297(5):101279
Peroxisomal-derived ether phospholipids link nucleotides to respirasome assembly.
Bennett CF, O'Malley KE, Perry EA, Balsa E, Latorre-Muro P, Riley CL, Luo C, Jedrychowski M, Gygi SP, Puigserver P
Nature chemical biology 2021 Jun;17(6):703-710
Nature chemical biology 2021 Jun;17(6):703-710
Limited survival and impaired hepatic fasting metabolism in mice with constitutive Rag GTPase signaling.
de la Calle Arregui C, Plata-Gómez AB, Deleyto-Seldas N, García F, Ortega-Molina A, Abril-Garrido J, Rodriguez E, Nemazanyy I, Tribouillard L, de Martino A, Caleiras E, Campos-Olivas R, Mulero F, Laplante M, Muñoz J, Pende M, Sabio G, Sabatini DM, Efeyan A
Nature communications 2021 Jun 16;12(1):3660
Nature communications 2021 Jun 16;12(1):3660
USP19 promotes hypoxia-induced mitochondrial division via FUNDC1 at ER-mitochondria contact sites.
Chai P, Cheng Y, Hou C, Yin L, Zhang D, Hu Y, Chen Q, Zheng P, Teng J, Chen J
The Journal of cell biology 2021 Jul 5;220(7)
The Journal of cell biology 2021 Jul 5;220(7)
Establishment and analysis of conditional Rab1- and Rab5-knockout cells using the auxin-inducible degron system.
Hatoyama Y, Homma Y, Hiragi S, Fukuda M
Journal of cell science 2021 Dec 15;134(24)
Journal of cell science 2021 Dec 15;134(24)
An engineered transcriptional reporter of protein localization identifies regulators of mitochondrial and ER membrane protein trafficking in high-throughput CRISPRi screens.
Coukos R, Yao D, Sanchez MI, Strand ET, Olive ME, Udeshi ND, Weissman JS, Carr SA, Bassik MC, Ting AY
eLife 2021 Aug 20;10
eLife 2021 Aug 20;10
A Network of Macrophages Supports Mitochondrial Homeostasis in the Heart.
Nicolás-Ávila JA, Lechuga-Vieco AV, Esteban-Martínez L, Sánchez-Díaz M, Díaz-García E, Santiago DJ, Rubio-Ponce A, Li JL, Balachander A, Quintana JA, Martínez-de-Mena R, Castejón-Vega B, Pun-García A, Través PG, Bonzón-Kulichenko E, García-Marqués F, Cussó L, A-González N, González-Guerra A, Roche-Molina M, Martin-Salamanca S, Crainiciuc G, Guzmán G, Larrazabal J, Herrero-Galán E, Alegre-Cebollada J, Lemke G, Rothlin CV, Jimenez-Borreguero LJ, Reyes G, Castrillo A, Desco M, Muñoz-Cánoves P, Ibáñez B, Torres M, Ng LG, Priori SG, Bueno H, Vázquez J, Cordero MD, Bernal JA, Enríquez JA, Hidalgo A
Cell 2020 Oct 1;183(1):94-109.e23
Cell 2020 Oct 1;183(1):94-109.e23
Drp1 Tubulates the ER in a GTPase-Independent Manner.
Adachi Y, Kato T, Yamada T, Murata D, Arai K, Stahelin RV, Chan DC, Iijima M, Sesaki H
Molecular cell 2020 Nov 19;80(4):621-632.e6
Molecular cell 2020 Nov 19;80(4):621-632.e6
Golgi-derived PI(4)P-containing vesicles drive late steps of mitochondrial division.
Nagashima S, Tábara LC, Tilokani L, Paupe V, Anand H, Pogson JH, Zunino R, McBride HM, Prudent J
Science (New York, N.Y.) 2020 Mar 20;367(6484):1366-1371
Science (New York, N.Y.) 2020 Mar 20;367(6484):1366-1371
Insufficiency of ciliary cholesterol in hereditary Zellweger syndrome.
Miyamoto T, Hosoba K, Itabashi T, Iwane AH, Akutsu SN, Ochiai H, Saito Y, Yamamoto T, Matsuura S
The EMBO journal 2020 Jun 17;39(12):e103499
The EMBO journal 2020 Jun 17;39(12):e103499
A cross-talk between epithelium and endothelium mediates human alveolar-capillary injury during SARS-CoV-2 infection.
Wang P, Luo R, Zhang M, Wang Y, Song T, Tao T, Li Z, Jin L, Zheng H, Chen W, Zhao M, Zheng Y, Qin J
Cell death & disease 2020 Dec 8;11(12):1042
Cell death & disease 2020 Dec 8;11(12):1042
Peroxisomes control mitochondrial dynamics and the mitochondrion-dependent apoptosis pathway.
Tanaka H, Okazaki T, Aoyama S, Yokota M, Koike M, Okada Y, Fujiki Y, Gotoh Y
Journal of cell science 2019 May 31;132(11)
Journal of cell science 2019 May 31;132(11)
Peroxisome turnover and diurnal modulation of antioxidant activity in retinal pigment epithelia utilizes microtubule-associated protein 1 light chain 3B (LC3B).
Daniele LL, Caughey J, Volland S, Sharp RC, Dhingra A, Williams DS, Philp NJ, Boesze-Battaglia K
American journal of physiology. Cell physiology 2019 Dec 1;317(6):C1194-C1204
American journal of physiology. Cell physiology 2019 Dec 1;317(6):C1194-C1204
F-actin patches associated with glutamatergic synapses control positioning of dendritic lysosomes.
van Bommel B, Konietzny A, Kobler O, Bär J, Mikhaylova M
The EMBO journal 2019 Aug 1;38(15):e101183
The EMBO journal 2019 Aug 1;38(15):e101183
In Vivo Deletion of β-Cell Drp1 Impairs Insulin Secretion Without Affecting Islet Oxygen Consumption.
Hennings TG, Chopra DG, DeLeon ER, VanDeusen HR, Sesaki H, Merrins MJ, Ku GM
Endocrinology 2018 Sep 1;159(9):3245-3256
Endocrinology 2018 Sep 1;159(9):3245-3256
Super-resolution imaging reveals the sub-diffraction phenotype of Zellweger Syndrome ghosts and wild-type peroxisomes.
Soliman K, Göttfert F, Rosewich H, Thoms S, Gärtner J
Scientific reports 2018 May 17;8(1):7809
Scientific reports 2018 May 17;8(1):7809
Autophagy defects and related genetic variations in renal cell carcinoma with eosinophilic cytoplasmic inclusions.
Yu Z, Ma J, Li X, Liu Y, Li M, Wang L, Zhao M, He H, Zhang Y, Rao Q, Zhao D, Wang Y, Fan L, Li P, Liu Y, Liu F, Zhang F, Ye J, Yan Q, Guo S, Wang Z
Scientific reports 2018 Jul 2;8(1):9972
Scientific reports 2018 Jul 2;8(1):9972
Isolation of Peroxisomes from Mouse Brain Using a Continuous Nycodenz Gradient: A Comparison to the Isolation of Liver and Kidney Peroxisomes.
Schönenberger MJ, Kovacs WJ
Methods in molecular biology (Clifton, N.J.) 2017;1595:13-26
Methods in molecular biology (Clifton, N.J.) 2017;1595:13-26
Dysferlin mediates membrane tubulation and links T-tubule biogenesis to muscular dystrophy.
Hofhuis J, Bersch K, Büssenschütt R, Drzymalski M, Liebetanz D, Nikolaev VO, Wagner S, Maier LS, Gärtner J, Klinge L, Thoms S
Journal of cell science 2017 Mar 1;130(5):841-852
Journal of cell science 2017 Mar 1;130(5):841-852
Novel regulatory roles of Mff and Drp1 in E3 ubiquitin ligase MARCH5-dependent degradation of MiD49 and Mcl1 and control of mitochondrial dynamics.
Cherok E, Xu S, Li S, Das S, Meltzer WA, Zalzman M, Wang C, Karbowski M
Molecular biology of the cell 2017 Feb 1;28(3):396-410
Molecular biology of the cell 2017 Feb 1;28(3):396-410
The functional readthrough extension of malate dehydrogenase reveals a modification of the genetic code.
Hofhuis J, Schueren F, Nötzel C, Lingner T, Gärtner J, Jahn O, Thoms S
Open biology 2016 Nov;6(11)
Open biology 2016 Nov;6(11)
Spectrum of PEX1 and PEX6 variants in Heimler syndrome.
Smith CE, Poulter JA, Levin AV, Capasso JE, Price S, Ben-Yosef T, Sharony R, Newman WG, Shore RC, Brookes SJ, Mighell AJ, Inglehearn CF
European journal of human genetics : EJHG 2016 Nov;24(11):1565-1571
European journal of human genetics : EJHG 2016 Nov;24(11):1565-1571
A Dendritic Golgi Satellite between ERGIC and Retromer.
Mikhaylova M, Bera S, Kobler O, Frischknecht R, Kreutz MR
Cell reports 2016 Jan 12;14(2):189-99
Cell reports 2016 Jan 12;14(2):189-99
Titration of mitochondrial fusion rescues Mff-deficient cardiomyopathy.
Chen H, Ren S, Clish C, Jain M, Mootha V, McCaffery JM, Chan DC
The Journal of cell biology 2015 Nov 23;211(4):795-805
The Journal of cell biology 2015 Nov 23;211(4):795-805
Conserved targeting information in mammalian and fungal peroxisomal tail-anchored proteins.
Buentzel J, Vilardi F, Lotz-Havla A, Gärtner J, Thoms S
Scientific reports 2015 Dec 2;5:17420
Scientific reports 2015 Dec 2;5:17420
Peroxisomal lactate dehydrogenase is generated by translational readthrough in mammals.
Schueren F, Lingner T, George R, Hofhuis J, Dickel C, Gärtner J, Thoms S
eLife 2014 Sep 23;3:e03640
eLife 2014 Sep 23;3:e03640
Hif-2α promotes degradation of mammalian peroxisomes by selective autophagy.
Walter KM, Schönenberger MJ, Trötzmüller M, Horn M, Elsässer HP, Moser AB, Lucas MS, Schwarz T, Gerber PA, Faust PL, Moch H, Köfeler HC, Krek W, Kovacs WJ
Cell metabolism 2014 Nov 4;20(5):882-897
Cell metabolism 2014 Nov 4;20(5):882-897
Peroxisomes are juxtaposed to strategic sites on mitochondria.
Cohen Y, Klug YA, Dimitrov L, Erez Z, Chuartzman SG, Elinger D, Yofe I, Soliman K, Gärtner J, Thoms S, Schekman R, Elbaz-Alon Y, Zalckvar E, Schuldiner M
Molecular bioSystems 2014 Jul;10(7):1742-8
Molecular bioSystems 2014 Jul;10(7):1742-8
Functional analysis of PEX13 mutation in a Zellweger syndrome spectrum patient reveals novel homooligomerization of PEX13 and its role in human peroxisome biogenesis.
Krause C, Rosewich H, Woehler A, Gärtner J
Human molecular genetics 2013 Oct 1;22(19):3844-57
Human molecular genetics 2013 Oct 1;22(19):3844-57
Charcot-Marie-Tooth disease-associated mutants of GDAP1 dissociate its roles in peroxisomal and mitochondrial fission.
Huber N, Guimaraes S, Schrader M, Suter U, Niemann A
EMBO reports 2013 Jun;14(6):545-52
EMBO reports 2013 Jun;14(6):545-52
Peroxisome deficiency-induced ER stress and SREBP-2 pathway activation in the liver of newborn PEX2 knock-out mice.
Kovacs WJ, Charles KN, Walter KM, Shackelford JE, Wikander TM, Richards MJ, Fliesler SJ, Krisans SK, Faust PL
Biochimica et biophysica acta 2012 Jun;1821(6):895-907
Biochimica et biophysica acta 2012 Jun;1821(6):895-907
Loss of ceramide synthase 3 causes lethal skin barrier disruption.
Jennemann R, Rabionet M, Gorgas K, Epstein S, Dalpke A, Rothermel U, Bayerle A, van der Hoeven F, Imgrund S, Kirsch J, Nickel W, Willecke K, Riezman H, Gröne HJ, Sandhoff R
Human molecular genetics 2012 Feb 1;21(3):586-608
Human molecular genetics 2012 Feb 1;21(3):586-608
Lymphoblastoid cell lines for diagnosis of peroxisome biogenesis disorders.
Grønborg S, Krätzner R, Rosewich H, Gärtner J
JIMD reports 2011;1:29-36
JIMD reports 2011;1:29-36
The unusual extended C-terminal helix of the peroxisomal α/β-hydrolase Lpx1 is involved in dimer contacts but dispensable for dimerization.
Thoms S, Hofhuis J, Thöing C, Gärtner J, Niemann HH
Journal of structural biology 2011 Sep;175(3):362-71
Journal of structural biology 2011 Sep;175(3):362-71
A role for myelin-associated peroxisomes in maintaining paranodal loops and axonal integrity.
Kassmann CM, Quintes S, Rietdorf J, Möbius W, Sereda MW, Nientiedt T, Saher G, Baes M, Nave KA
FEBS letters 2011 Jul 21;585(14):2205-11
FEBS letters 2011 Jul 21;585(14):2205-11
Typical cMRI pattern as diagnostic clue for D-bifunctional protein deficiency without apparent biochemical abnormalities in plasma.
Grønborg S, Krätzner R, Spiegler J, Ferdinandusse S, Wanders RJ, Waterham HR, Gärtner J
American journal of medical genetics. Part A 2010 Nov;152A(11):2845-9
American journal of medical genetics. Part A 2010 Nov;152A(11):2845-9
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Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- human liver tissue were subjected to SDS PAGE followed by western blot with 10594-1-AP(PEX14 antibody) at dilution of 1:500
- Sample type
- tissue
