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Western blot
ELISAAntibody data
- Antibody Data
- Antigen structure
- References [10]
- Comments [0]
- Validations
- Western blot [1]
- Immunocytochemistry [1]
- Immunohistochemistry [1]
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- Product number
- 11003-1-AP - Provider product page
- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#11003-1-AP, RRID:AB_2202516
- Product name
- TCOF1 antibody
- Antibody type
- Polyclonal
- Description
- KD/KO validated TCOF1 antibody (Cat. #11003-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse and has been validated for the following applications: IF, IHC, WB, ELISA.
- Reactivity
- Human, Mouse
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references TCOF1 promotes the colorectal cancer progression by stabilizing β-catenin.
Henipaviruses and lyssaviruses target nucleolar treacle protein and regulate ribosomal RNA synthesis.
An evolutionarily nascent architecture underlying the formation and emergence of biomolecular condensates.
TCOF1 coordinates oncogenic activation and rRNA production and promotes tumorigenesis in HCC.
TRPV1 Activation Promotes β-arrestin2 Interaction with the Ribosomal Biogenesis Machinery in the Nucleolus:Implications for p53 Regulation and Neurite Outgrowth.
Multisite dependency of an E3 ligase controls monoubiquitylation-dependent cell fate decisions.
Viral regulation of host cell biology by hijacking of the nucleolar DNA-damage response.
Cell-fate determination by ubiquitin-dependent regulation of translation.
CRISPR/Cas9 allows efficient and complete knock-in of a destabilization domain-tagged essential protein in a human cell line, allowing rapid knockdown of protein function.
Treacher Collins syndrome TCOF1 protein cooperates with NBS1 in the DNA damage response.
Yun H, You JE, Hong JK, Kim DY, Lee JU, Kang DH, Ryu YS, Koh DI, Jin DH
Medical oncology (Northwood, London, England) 2023 Nov 7;40(12):348
Medical oncology (Northwood, London, England) 2023 Nov 7;40(12):348
Henipaviruses and lyssaviruses target nucleolar treacle protein and regulate ribosomal RNA synthesis.
Rawlinson SM, Zhao T, Ardipradja K, Zhang Y, Veugelers PF, Harper JA, David CT, Sundaramoorthy V, Moseley GW
Traffic (Copenhagen, Denmark) 2023 Mar;24(3):146-157
Traffic (Copenhagen, Denmark) 2023 Mar;24(3):146-157
An evolutionarily nascent architecture underlying the formation and emergence of biomolecular condensates.
Jaberi-Lashkari N, Lee B, Aryan F, Calo E
Cell reports 2023 Aug 29;42(8):112955
Cell reports 2023 Aug 29;42(8):112955
TCOF1 coordinates oncogenic activation and rRNA production and promotes tumorigenesis in HCC.
Wu C, Xia D, Wang D, Wang S, Sun Z, Xu B, Zhang D
Cancer science 2022 Feb;113(2):553-564
Cancer science 2022 Feb;113(2):553-564
TRPV1 Activation Promotes β-arrestin2 Interaction with the Ribosomal Biogenesis Machinery in the Nucleolus:Implications for p53 Regulation and Neurite Outgrowth.
Hassan A, Iftinca M, Young D, Flynn R, Agosti F, Abdullah N, Defaye M, Scott MGH, Dufour A, Altier C
International journal of molecular sciences 2021 Feb 25;22(5)
International journal of molecular sciences 2021 Feb 25;22(5)
Multisite dependency of an E3 ligase controls monoubiquitylation-dependent cell fate decisions.
Werner A, Baur R, Teerikorpi N, Kaya DU, Rape M
eLife 2018 Jul 12;7
eLife 2018 Jul 12;7
Viral regulation of host cell biology by hijacking of the nucleolar DNA-damage response.
Rawlinson SM, Zhao T, Rozario AM, Rootes CL, McMillan PJ, Purcell AW, Woon A, Marsh GA, Lieu KG, Wang LF, Netter HJ, Bell TDM, Stewart CR, Moseley GW
Nature communications 2018 Aug 3;9(1):3057
Nature communications 2018 Aug 3;9(1):3057
Cell-fate determination by ubiquitin-dependent regulation of translation.
Werner A, Iwasaki S, McGourty CA, Medina-Ruiz S, Teerikorpi N, Fedrigo I, Ingolia NT, Rape M
Nature 2015 Sep 24;525(7570):523-7
Nature 2015 Sep 24;525(7570):523-7
CRISPR/Cas9 allows efficient and complete knock-in of a destabilization domain-tagged essential protein in a human cell line, allowing rapid knockdown of protein function.
Park A, Won ST, Pentecost M, Bartkowski W, Lee B
PloS one 2014;9(4):e95101
PloS one 2014;9(4):e95101
Treacher Collins syndrome TCOF1 protein cooperates with NBS1 in the DNA damage response.
Ciccia A, Huang JW, Izhar L, Sowa ME, Harper JW, Elledge SJ
Proceedings of the National Academy of Sciences of the United States of America 2014 Dec 30;111(52):18631-6
Proceedings of the National Academy of Sciences of the United States of America 2014 Dec 30;111(52):18631-6
No comments: Submit comment
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- HeLa cells were subjected to SDS PAGE followed by western blot with 11003-1-AP(TCOF1 antibody) at dilution of 1:1000
- Sample type
- cell line
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- Immunofluorescent analysis of MCF-7 cells, using TCOF1 antibody 11003-1-AP at 1:50 dilution and FITC-labeled donkey anti-rabbit IgG(green). Blue pseudocolor = DAPI (fluorescent DNA dye).
- Sample type
- cell line
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- Immunohistochemical of paraffin-embedded human lymphoma using 11003-1-AP(TCOF1 antibody) at dilution of 1:50 (under 10x lens)
- Sample type
- tissue
