21754-1-AP

antibody from Proteintech Group

Targeting: PDE4C DPDE1

Western blot (Data presented on provider website)

ELISA (Data presented on provider website)

Antibody Data

Product number

21754-1-AP

Provider

Proteintech Group

Proper citation

Proteintech Cat#21754-1-AP, RRID:AB_10860265

Product name

PDE4C antibody

Antibody type

Polyclonal

Description

PDE4C antibody (Cat. #21754-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse, rat and has been validated for the following applications: WB,ELISA.

Reactivity

Human, Mouse, Rat

Host

Rabbit

Conjugate

Unconjugated

Isotype

IgG

Vial size

20ul, 150ul

References

Submitted references

Inhibition of phosphodiesterase 4D suppresses mTORC1 signaling and pancreatic cancer growth.

Jeong MH, Urquhart G, Lewis C, Chi Z, Jewell JL
JCI insight 2023 Jul 10;8(13)

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Inhibition of prolyl hydroxylases increases hepatic insulin and decreases glucagon sensitivity by an HIF-2α-dependent mechanism.

Riopel M, Moon JS, Bandyopadhyay GK, You S, Lam K, Liu X, Kisseleva T, Brenner D, Lee YS
Molecular metabolism 2020 Nov;41:101039

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Inhibition of PDE4/PDE4B improves renal function and ameliorates inflammation in cisplatin-induced acute kidney injury.

Xu M, Yu X, Meng X, Huang S, Zhang Y, Zhang A, Jia Z
American journal of physiology. Renal physiology 2020 Mar 1;318(3):F576-F588

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DC591017, a phosphodiesterase-4 (PDE4) inhibitor with robust anti-inflammation through regulating PKA-CREB signaling.

Li H, Li J, Zhang X, Feng C, Fan C, Yang X, Zhang R, Zhu F, Zhou Y, Xu Y, Liu H, Tang W
Biochemical pharmacology 2020 Jul;177:113958