Antibody data
- Antibody Data
- Antigen structure
- References [7]
- Comments [0]
- Validations [0]
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Validation data
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- Product number
- 21754-1-AP - Provider product page

- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#21754-1-AP, RRID:AB_10860265
- Product name
- PDE4C antibody
- Antibody type
- Polyclonal
- Description
- PDE4C antibody (Cat. #21754-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse, rat and has been validated for the following applications: WB,ELISA.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references Aberrant TCF21 upregulation in adenomyosis impairs endometrial decidualization by increasing PDE4C expression.
Analysis of the effects of M2 macrophage-derived PDE4C on the prognosis, metastasis and immunotherapy benefit of osteosarcoma.
A novel protein encoded by circLARP1B promotes the proliferation and migration of vascular smooth muscle cells by suppressing cAMP signaling.
Inhibition of phosphodiesterase 4D suppresses mTORC1 signaling and pancreatic cancer growth.
Inhibition of prolyl hydroxylases increases hepatic insulin and decreases glucagon sensitivity by an HIF-2α-dependent mechanism.
Inhibition of PDE4/PDE4B improves renal function and ameliorates inflammation in cisplatin-induced acute kidney injury.
DC591017, a phosphodiesterase-4 (PDE4) inhibitor with robust anti-inflammation through regulating PKA-CREB signaling.
Yu R, Wei C, Li G, Ouyang J, Liu N, Gu N, Lin Y, Xu H
Biochimica et biophysica acta. Molecular basis of disease 2025 Jan;1871(1):167526
Biochimica et biophysica acta. Molecular basis of disease 2025 Jan;1871(1):167526
Analysis of the effects of M2 macrophage-derived PDE4C on the prognosis, metastasis and immunotherapy benefit of osteosarcoma.
Pan F, Pan R, Hu R, Zhang H, Lei S, Zhang L, Zhou C, Zeng Z, Tian X, Xie Q
Journal of cellular and molecular medicine 2024 May;28(10):e18395
Journal of cellular and molecular medicine 2024 May;28(10):e18395
A novel protein encoded by circLARP1B promotes the proliferation and migration of vascular smooth muscle cells by suppressing cAMP signaling.
Lu P, Fan J, Li B, Wang X, Song M
Atherosclerosis 2024 Aug;395:117575
Atherosclerosis 2024 Aug;395:117575
Inhibition of phosphodiesterase 4D suppresses mTORC1 signaling and pancreatic cancer growth.
Jeong MH, Urquhart G, Lewis C, Chi Z, Jewell JL
JCI insight 2023 Jul 10;8(13)
JCI insight 2023 Jul 10;8(13)
Inhibition of prolyl hydroxylases increases hepatic insulin and decreases glucagon sensitivity by an HIF-2α-dependent mechanism.
Riopel M, Moon JS, Bandyopadhyay GK, You S, Lam K, Liu X, Kisseleva T, Brenner D, Lee YS
Molecular metabolism 2020 Nov;41:101039
Molecular metabolism 2020 Nov;41:101039
Inhibition of PDE4/PDE4B improves renal function and ameliorates inflammation in cisplatin-induced acute kidney injury.
Xu M, Yu X, Meng X, Huang S, Zhang Y, Zhang A, Jia Z
American journal of physiology. Renal physiology 2020 Mar 1;318(3):F576-F588
American journal of physiology. Renal physiology 2020 Mar 1;318(3):F576-F588
DC591017, a phosphodiesterase-4 (PDE4) inhibitor with robust anti-inflammation through regulating PKA-CREB signaling.
Li H, Li J, Zhang X, Feng C, Fan C, Yang X, Zhang R, Zhu F, Zhou Y, Xu Y, Liu H, Tang W
Biochemical pharmacology 2020 Jul;177:113958
Biochemical pharmacology 2020 Jul;177:113958
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