Antibody data
- Antibody Data
- Antigen structure
- References [4]
- Comments [0]
- Validations
- Western blot [1]
- Immunohistochemistry [1]
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Validation data
Reference
Comment
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- Product number
- 12436-1-AP - Provider product page

- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#12436-1-AP, RRID:AB_2301798
- Product name
- SHC3 antibody
- Antibody type
- Polyclonal
- Description
- SHC3 antibody (Cat. #12436-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse, rat and has been validated for the following applications: IHC, IP, WB,ELISA.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references Functionally distinct ALK and ROS1 fusions detected in infant-type hemispheric gliomas converge on STAT3 and SHP2 activation.
RETRACTED: Short communication: Upregulation of hypoxia/reoxygenation-induced Shc3 by downregulated miR-455-5p, suppresses trophoblast invasion and is associated with placental inflammation and angiogenesis in preeclampsia.
The Long Non-Coding RNA AC006329.1 Facilitates Hepatocellular Carcinoma Progression and Metastasis by Regulating miR-127-5p/SHC3/ERK Axis.
Lysate microarrays enable high-throughput, quantitative investigations of cellular signaling.
Postlmayr A, Sanchez Bergman A, Torrejon Diaz J, Ciraulo B, Yan S, Hofmann N, Carbajal S, Dobler R, Machaalani C, Schönholzer MT, Priego Gonzalez L, De Micheli AJ, Berenjeno-Correa E, Baroncini L, Grotzer MA, Tabori U, Hawkins C, Ayrault O, Zuckermann M, Baumgartner M, Guerreiro Stücklin AS
Cell reports 2026 Mar 24;45(3):117046
Cell reports 2026 Mar 24;45(3):117046
RETRACTED: Short communication: Upregulation of hypoxia/reoxygenation-induced Shc3 by downregulated miR-455-5p, suppresses trophoblast invasion and is associated with placental inflammation and angiogenesis in preeclampsia.
Gong HZ, Guan J, Pan YZ, Ding HJ, Shi AW, Gu N
PloS one 2025;20(1):e0314544
PloS one 2025;20(1):e0314544
The Long Non-Coding RNA AC006329.1 Facilitates Hepatocellular Carcinoma Progression and Metastasis by Regulating miR-127-5p/SHC3/ERK Axis.
Kong XX, Yang X, Jiang WJ, Zhu M, Kong LB
Journal of hepatocellular carcinoma 2023;10:1085-1103
Journal of hepatocellular carcinoma 2023;10:1085-1103
Lysate microarrays enable high-throughput, quantitative investigations of cellular signaling.
Sevecka M, Wolf-Yadlin A, MacBeath G
Molecular & cellular proteomics : MCP 2011 Apr;10(4):M110.005363
Molecular & cellular proteomics : MCP 2011 Apr;10(4):M110.005363
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Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image

- Experimental details
- BxPC-3 cells were subjected to SDS PAGE followed by western blot with 12436-1-AP(SHC3 antibody) at dilution of 1:400
- Sample type
- cell line
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image

- Experimental details
- The SHC3 antibody from Proteintech is a rabbit polyclonal antibody to a recombinant protein of human SHC3. This antibody recognizes human, mouse, rat antigen. The SHC3 antibody has been validated for the following applications: ELISA, WB, IHC analysis.