CHIC1

This gene encodes a cysteine-rich hydrophobic (CHIC) domain-containing protein, and is one of the few protein-coding genes found near the X-inactivation center. Studies in mouse indicate that the mouse ortholog of this gene is subject to X-inactivation in mouse. Experiments with other CHIC domain-containing family members show that the cysteine residues are palmitoylated post-translationally, resulting in membrane association. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, May 2017]

Description

Cysteine rich hydrophobic domain 1

Tissue specificity

Low tissue specificity

Subcell location

Nuclear speckles, Vesicles, Cytosol

Predicted location

Membrane

Protein family

Mapped to neXtProt
Mapped to UniProt SWISS-PROT
Predicted membrane proteins

Chromosome

X (73563200 - 73687102)

Ensembl ID

ENSG00000204116  (ver. 103.38)

Orthologs

Mouse Chic1: ENSMUSG00000031327

UniProt

Q5VXU3

neXtProt

NX_Q5VXU3

Human splice variants
Mouse splice variants

Protein structure