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- References [14]
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- Validations
- Western blot [1]
- Immunoprecipitation [1]
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- Product number
- 12798-1-AP - Provider product page
- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#12798-1-AP, RRID:AB_2186555
- Product name
- SECISBP2 antibody
- Antibody type
- Polyclonal
- Description
- KD/KO validated SECISBP2 antibody (Cat. #12798-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse, rat and has been validated for the following applications: IF, IP, WB, ELISA.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references Sbp2l contributes to oligodendrocyte maturation through translational control in Tcf7l2 signaling.
The expression of essential selenoproteins during development requires SECIS-binding protein 2-like.
Ribosome stalling during selenoprotein translation exposes a ferroptosis vulnerability.
Identification of a novel endogenous long non-coding RNA that inhibits selenoprotein P translation.
Selenocysteine insertion sequence binding protein 2 (Sbp2) in the sex-specific regulation of selenoprotein gene expression in mouse pancreatic islets.
Role of the Thyroid Gland in Expression of the Thyroid Phenotype of Sbp2-Deficient Mice.
Selenium-sensitive miRNA-181a-5p targeting SBP2 regulates selenoproteins expression in cartilage.
Loss of selenocysteine insertion sequence binding protein 2 suppresses the proliferation, migration/invasion and hormone secretion of human trophoblast cells via the PI3K/Akt and ERK signaling pathway.
Thyroid Hormone Metabolism Defects in a Mouse Model of SBP2 Deficiency.
The Selenocysteine-Specific Elongation Factor Contains Unique Sequences That Are Required for Both Nuclear Export and Selenocysteine Incorporation.
SELENOPROTEINS. CRL2 aids elimination of truncated selenoproteins produced by failed UGA/Sec decoding.
Selective up-regulation of human selenoproteins in response to oxidative stress.
Selective up-regulation of human selenoproteins in response to oxidative stress.
Interplay between selenium levels, selenoprotein expression, and replicative senescence in WI-38 human fibroblasts.
Yugami M, Hayakawa-Yano Y, Ogasawara T, Yokoyama K, Furukawa T, Hara H, Hashikami K, Tsuji I, Takebayashi H, Araki S, Okano H, Yano M
iScience 2023 Dec 15;26(12):108451
iScience 2023 Dec 15;26(12):108451
The expression of essential selenoproteins during development requires SECIS-binding protein 2-like.
Kiledjian NT, Shah R, Vetick MB, Copeland PR
Life science alliance 2022 May;5(5)
Life science alliance 2022 May;5(5)
Ribosome stalling during selenoprotein translation exposes a ferroptosis vulnerability.
Li Z, Ferguson L, Deol KK, Roberts MA, Magtanong L, Hendricks JM, Mousa GA, Kilinc S, Schaefer K, Wells JA, Bassik MC, Goga A, Dixon SJ, Ingolia NT, Olzmann JA
Nature chemical biology 2022 Jul;18(7):751-761
Nature chemical biology 2022 Jul;18(7):751-761
Identification of a novel endogenous long non-coding RNA that inhibits selenoprotein P translation.
Mita Y, Uchida R, Yasuhara S, Kishi K, Hoshi T, Matsuo Y, Yokooji T, Shirakawa Y, Toyama T, Urano Y, Inada T, Noguchi N, Saito Y
Nucleic acids research 2021 Jul 9;49(12):6893-6907
Nucleic acids research 2021 Jul 9;49(12):6893-6907
Selenocysteine insertion sequence binding protein 2 (Sbp2) in the sex-specific regulation of selenoprotein gene expression in mouse pancreatic islets.
Chellan B, Zhao L, Landeche M, Carmean CM, Dumitrescu AM, Sargis RM
Scientific reports 2020 Oct 29;10(1):18568
Scientific reports 2020 Oct 29;10(1):18568
Role of the Thyroid Gland in Expression of the Thyroid Phenotype of Sbp2-Deficient Mice.
Fujisawa H, Korwutthikulrangsri M, Fu J, Liao XH, Dumitrescu AM
Endocrinology 2020 May 1;161(5)
Endocrinology 2020 May 1;161(5)
Selenium-sensitive miRNA-181a-5p targeting SBP2 regulates selenoproteins expression in cartilage.
Min Z, Guo Y, Sun M, Hussain S, Zhao Y, Guo D, Huang H, Heng L, Zhang F, Ning Q, Han Y, Xu P, Zhong N, Sun J, Lu S
Journal of cellular and molecular medicine 2018 Dec;22(12):5888-5898
Journal of cellular and molecular medicine 2018 Dec;22(12):5888-5898
Loss of selenocysteine insertion sequence binding protein 2 suppresses the proliferation, migration/invasion and hormone secretion of human trophoblast cells via the PI3K/Akt and ERK signaling pathway.
Li M, Cheng W, Luo J, Hu X, Nie T, Lai H, Zheng X, Li F, Li H
Placenta 2017 Jul;55:81-89
Placenta 2017 Jul;55:81-89
Thyroid Hormone Metabolism Defects in a Mouse Model of SBP2 Deficiency.
Fu J, Fujisawa H, Follman B, Liao XH, Dumitrescu AM
Endocrinology 2017 Dec 1;158(12):4317-4330
Endocrinology 2017 Dec 1;158(12):4317-4330
The Selenocysteine-Specific Elongation Factor Contains Unique Sequences That Are Required for Both Nuclear Export and Selenocysteine Incorporation.
Dubey A, Copeland PR
PloS one 2016;11(11):e0165642
PloS one 2016;11(11):e0165642
SELENOPROTEINS. CRL2 aids elimination of truncated selenoproteins produced by failed UGA/Sec decoding.
Lin HC, Ho SC, Chen YY, Khoo KH, Hsu PH, Yen HC
Science (New York, N.Y.) 2015 Jul 3;349(6243):91-5
Science (New York, N.Y.) 2015 Jul 3;349(6243):91-5
Selective up-regulation of human selenoproteins in response to oxidative stress.
Zahia TH, Yona L, Anne-Laure B, Laurent C
Free radical biology & medicine 2014 Oct;75 Suppl 1:S25
Free radical biology & medicine 2014 Oct;75 Suppl 1:S25
Selective up-regulation of human selenoproteins in response to oxidative stress.
Touat-Hamici Z, Legrain Y, Bulteau AL, Chavatte L
The Journal of biological chemistry 2014 May 23;289(21):14750-61
The Journal of biological chemistry 2014 May 23;289(21):14750-61
Interplay between selenium levels, selenoprotein expression, and replicative senescence in WI-38 human fibroblasts.
Legrain Y, Touat-Hamici Z, Chavatte L
The Journal of biological chemistry 2014 Feb 28;289(9):6299-310
The Journal of biological chemistry 2014 Feb 28;289(9):6299-310
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Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- HeLa cells were subjected to SDS PAGE followed by western blot with 12798-1-AP(SECISBP2 antibody) at dilution of 1:400
- Sample type
- cell line
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- The SECISBP2 antibody from Proteintech is a rabbit polyclonal antibody to a recombinant protein of human SECISBP2. This antibody recognizes human,mouse,rat antigen. The SECISBP2 antibody has been validated for the following applications: ELISA, WB, IP analysis.
