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- References [20]
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- Product number
- 10236-1-AP - Provider product page
- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#10236-1-AP, RRID:AB_2215216
- Product name
- VPS35 antibody
- Antibody type
- Polyclonal
- Description
- VPS35 antibody (Cat. #10236-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse, rat and has been validated for the following applications: IF, IP, WB,ELISA.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references Loss of VMP1 Impairs Tight Junction Recycling and Aggravates Intestinal Barrier Dysfunction in Inflammatory Bowel Disease.
Targeting sorting nexin 3 to treat pulmonary fibrosis by dual modulating Wnt/β-catenin signaling.
EHBP1 suppresses liver fibrosis in metabolic dysfunction-associated steatohepatitis.
Leucine-Rich Repeat Kinase 1 Signaling Targets Proteins Critical for Endosome/Lysosome Sorting and Trafficking in Osteoclasts.
Noncanonical roles of ATG5 and membrane atg8ylation in retromer assembly and function.
Exploring the role of mitochondrial dysfunction-related genes in osteoporosis using weighted gene co-expression network analysis and machine learning.
Negative interplay between HIV-1 Gag and amyloid precursor protein centers around competition for VPS4A and TSG101.
SNX3 mediates heart failure by interacting with HMGB1 and subsequently facilitating its nuclear-cytoplasmic translocation.
Noncanonical roles of ATG5 and membrane atg8ylation in retromer assembly and function.
Absence of motor impairments or pathological changes in TMEM230 knockout rats.
Identification of high-performing antibodies for Vacuolar protein sorting-associated protein 35 (hVPS35) for use in Western Blot, immunoprecipitation and immunofluorescence.
Diabetes is accompanied by changes in the levels of proteins involved in endosomal GLUT4 trafficking in obese human skeletal muscle.
SNX27 suppresses SARS-CoV-2 infection by inhibiting viral lysosome/late endosome entry.
Sorting nexin 3 induces heart failure via promoting retromer-dependent nuclear trafficking of STAT3.
Regulation of NMDA receptor trafficking and gating by activity-dependent CaMKIIα phosphorylation of the GluN2A subunit.
A genome-wide CRISPR screen identifies host factors that regulate SARS-CoV-2 entry.
Retromer and Rab2-dependent trafficking mediate PS1 degradation by proteasomes in endocytic disturbance.
Dynein Dysfunction Reproduces Age-Dependent Retromer Deficiency: Concomitant Disruption of Retrograde Trafficking Is Required for Alteration in β-Amyloid Precursor Protein Metabolism.
VPS35 pathogenic mutations confer no dominant toxicity but partial loss of function in Drosophila and genetically interact with parkin.
Schisandrin B protects PC12 cells by decreasing the expression of amyloid precursor protein and vacuolar protein sorting 35.
Zhao J, Zou J, Zhou C, Wang Y, Liu Y, Zhou Y, Wang Y, Zhang X, Yang H, Yin H, Bai D, Zhao Y, Lu N
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2026 May;13(25):e21681
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2026 May;13(25):e21681
Targeting sorting nexin 3 to treat pulmonary fibrosis by dual modulating Wnt/β-catenin signaling.
Ma D, Yu W, Zhou H, Lin R, Sun X, Peng M, Lin C, Du H, Li Y, Liang H, Sun D, Liu P, Lu J
Cell death & disease 2026 Jan 15;17(1):43
Cell death & disease 2026 Jan 15;17(1):43
EHBP1 suppresses liver fibrosis in metabolic dysfunction-associated steatohepatitis.
Ma F, Longo M, Meroni M, Bhattacharya D, Paolini E, Mughal S, Hussain S, Anand SK, Gupta N, Zhu Y, Navarro-Corcuera A, Li K, Prakash S, Cogliati B, Wang S, Huang X, Wang X, Yurdagul A Jr, Rom O, Wang L, Fried SK, Dongiovanni P, Friedman SL, Cai B
Cell metabolism 2025 May 6;37(5):1152-1170.e7
Cell metabolism 2025 May 6;37(5):1152-1170.e7
Leucine-Rich Repeat Kinase 1 Signaling Targets Proteins Critical for Endosome/Lysosome Sorting and Trafficking in Osteoclasts.
Xing W, Chen Y, Udayakumar A, Zhao H, Mohan S
Biology 2025 Mar 24;14(4)
Biology 2025 Mar 24;14(4)
Noncanonical roles of ATG5 and membrane atg8ylation in retromer assembly and function.
Paddar MA, Wang F, Trosdal ES, Hendrix E, He Y, Salemi MR, Mudd M, Jia J, Duque T, Javed R, Phinney BS, Deretic V
eLife 2025 Jan 7;13
eLife 2025 Jan 7;13
Exploring the role of mitochondrial dysfunction-related genes in osteoporosis using weighted gene co-expression network analysis and machine learning.
Zeng HB, Yuan XT, Wu LG, Zhang RK, Yan K, Lai XB, Xu P, Yao XM
European journal of medical research 2025 Dec 16;31(1):103
European journal of medical research 2025 Dec 16;31(1):103
Negative interplay between HIV-1 Gag and amyloid precursor protein centers around competition for VPS4A and TSG101.
Gu F, Naghavi MH
Proceedings of the National Academy of Sciences of the United States of America 2025 Aug 26;122(34):e2503988122
Proceedings of the National Academy of Sciences of the United States of America 2025 Aug 26;122(34):e2503988122
SNX3 mediates heart failure by interacting with HMGB1 and subsequently facilitating its nuclear-cytoplasmic translocation.
Li H, Peng MX, Yang RX, Chen JX, Wang YM, Wang PX, Hu YH, Pan DY, Liu PQ, Lu J
Acta pharmacologica Sinica 2025 Apr;46(4):964-975
Acta pharmacologica Sinica 2025 Apr;46(4):964-975
Noncanonical roles of ATG5 and membrane atg8ylation in retromer assembly and function.
Paddar MA, Wang F, Trosdal ES, Hendrix E, He Y, Salemi M, Mudd M, Jia J, Duque TLA, Javed R, Phinney B, Deretic V
bioRxiv : the preprint server for biology 2024 Oct 14;
bioRxiv : the preprint server for biology 2024 Oct 14;
Absence of motor impairments or pathological changes in TMEM230 knockout rats.
Zhang W, Peng H, Yang D, Song G, He J, Zhou Y, Huang C, Huang B
Neuroscience letters 2024 Aug 10;837:137921
Neuroscience letters 2024 Aug 10;837:137921
Identification of high-performing antibodies for Vacuolar protein sorting-associated protein 35 (hVPS35) for use in Western Blot, immunoprecipitation and immunofluorescence.
Ayoubi R, Fotouhi M, Southern K, McPherson PS, Laflamme C, NeuroSGC/YCharOS/EDDU collaborative group, ABIF consortium
F1000Research 2023;12:452
F1000Research 2023;12:452
Diabetes is accompanied by changes in the levels of proteins involved in endosomal GLUT4 trafficking in obese human skeletal muscle.
Livingstone R, Bryant NJ, Boyle JG, Petrie JR, Gould GW
Endocrinology, diabetes & metabolism 2022 Sep;5(5):e361
Endocrinology, diabetes & metabolism 2022 Sep;5(5):e361
SNX27 suppresses SARS-CoV-2 infection by inhibiting viral lysosome/late endosome entry.
Yang B, Jia Y, Meng Y, Xue Y, Liu K, Li Y, Liu S, Li X, Cui K, Shang L, Cheng T, Zhang Z, Hou Y, Yang X, Yan H, Duan L, Tong Z, Wu C, Liu Z, Gao S, Zhuo S, Huang W, Gao GF, Qi J, Shang G
Proceedings of the National Academy of Sciences of the United States of America 2022 Jan 25;119(4)
Proceedings of the National Academy of Sciences of the United States of America 2022 Jan 25;119(4)
Sorting nexin 3 induces heart failure via promoting retromer-dependent nuclear trafficking of STAT3.
Lu J, Xu S, Huo Y, Sun D, Hu Y, Wang J, Zhang X, Wang P, Li Z, Liang M, Wu Z, Liu P
Cell death and differentiation 2021 Oct;28(10):2871-2887
Cell death and differentiation 2021 Oct;28(10):2871-2887
Regulation of NMDA receptor trafficking and gating by activity-dependent CaMKIIα phosphorylation of the GluN2A subunit.
Yong XLH, Zhang L, Yang L, Chen X, Tan JZA, Yu X, Chandra M, Livingstone E, Widagdo J, Vieira MM, Roche KW, Lynch JW, Keramidas A, Collins BM, Anggono V
Cell reports 2021 Jul 6;36(1):109338
Cell reports 2021 Jul 6;36(1):109338
A genome-wide CRISPR screen identifies host factors that regulate SARS-CoV-2 entry.
Zhu Y, Feng F, Hu G, Wang Y, Yu Y, Zhu Y, Xu W, Cai X, Sun Z, Han W, Ye R, Qu D, Ding Q, Huang X, Chen H, Xu W, Xie Y, Cai Q, Yuan Z, Zhang R
Nature communications 2021 Feb 11;12(1):961
Nature communications 2021 Feb 11;12(1):961
Retromer and Rab2-dependent trafficking mediate PS1 degradation by proteasomes in endocytic disturbance.
Ueda N, Tomita T, Yanagisawa K, Kimura N
Journal of neurochemistry 2016 May;137(4):647-58
Journal of neurochemistry 2016 May;137(4):647-58
Dynein Dysfunction Reproduces Age-Dependent Retromer Deficiency: Concomitant Disruption of Retrograde Trafficking Is Required for Alteration in β-Amyloid Precursor Protein Metabolism.
Kimura N, Samura E, Suzuki K, Okabayashi S, Shimozawa N, Yasutomi Y
The American journal of pathology 2016 Jul;186(7):1952-1966
The American journal of pathology 2016 Jul;186(7):1952-1966
VPS35 pathogenic mutations confer no dominant toxicity but partial loss of function in Drosophila and genetically interact with parkin.
Malik BR, Godena VK, Whitworth AJ
Human molecular genetics 2015 Nov 1;24(21):6106-17
Human molecular genetics 2015 Nov 1;24(21):6106-17
Schisandrin B protects PC12 cells by decreasing the expression of amyloid precursor protein and vacuolar protein sorting 35.
Yan M, Mao S, Dong H, Liu B, Zhang Q, Pan G, Fu Z
Neural regeneration research 2012 Mar 25;7(9):652-8
Neural regeneration research 2012 Mar 25;7(9):652-8
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Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- The VPS35 antibody from Proteintech is a rabbit polyclonal antibody to a recombinant protein of human VPS35. This antibody recognizes human,mouse,rat antigen. The VPS35 antibody has been validated for the following applications: ELISA, WB analysis.
