Antibody data
- Antibody Data
- Antigen structure
- References [4]
- Comments [0]
- Validations
- Western blot [1]
- Immunohistochemistry [1]
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Validation data
Reference
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- Product number
- HPA017956 - Provider product page
- Provider
- Atlas Antibodies
- Proper citation
- Atlas Antibodies Cat#HPA017956, RRID:AB_1852408
- Product name
- Anti-KIAA1462
- Antibody type
- Polyclonal
- Description
- Polyclonal Antibody against Human KIAA1462, Gene description: KIAA1462, Alternative Gene Names: JCAD, Validated applications: WB, IHC, ICC, Uniprot ID: Q9P266, Storage: Store at +4°C for short term storage. Long time storage is recommended at -20°C.
- Reactivity
- Human
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 100 µl
- Concentration
- 0.1 mg/ml
- Storage
- Store at +4°C for short term storage. Long time storage is recommended at -20°C.
- Handling
- The antibody solution should be gently mixed before use.
Submitted references Protein interaction networks in the vasculature prioritize genes and pathways underlying coronary artery disease
JCAD expression and localization in human blood endothelial cells
A key role for the novel coronary artery disease gene JCAD in atherosclerosis via shear stress mechanotransduction
JCAD , a Gene at the 10p11 Coronary Artery Disease Locus, Regulates Hippo Signaling in Endothelial Cells
Zhu Q, Hsu Y, Lassen F, MacDonald B, Stead S, Malolepsza E, Kim A, Li T, Mizoguchi T, Schenone M, Guzman G, Tanenbaum B, Fornelos N, Carr S, Gupta R, Ellinor P, Lage K
Communications Biology 2024;7(1)
Communications Biology 2024;7(1)
JCAD expression and localization in human blood endothelial cells
Shigeoka M, Arimoto S, Akashi M
Heliyon 2020;6(10):e05121
Heliyon 2020;6(10):e05121
A key role for the novel coronary artery disease gene JCAD in atherosclerosis via shear stress mechanotransduction
Douglas G, Mehta V, Al Haj Zen A, Akoumianakis I, Goel A, Rashbrook V, Trelfa L, Donovan L, Drydale E, Chuaiphichai S, Antoniades C, Watkins H, Kyriakou T, Tzima E, Channon K
Cardiovascular Research 2020;116(11):1863-1874
Cardiovascular Research 2020;116(11):1863-1874
JCAD , a Gene at the 10p11 Coronary Artery Disease Locus, Regulates Hippo Signaling in Endothelial Cells
Jones P, Kaiser M, Ghaderi Najafabadi M, Koplev S, Zhao Y, Douglas G, Kyriakou T, Andrews S, Rajmohan R, Watkins H, Channon K, Ye S, Yang X, Björkegren J, Samani N, Webb T
Arteriosclerosis, Thrombosis, and Vascular Biology 2018;38(8):1711-1722
Arteriosclerosis, Thrombosis, and Vascular Biology 2018;38(8):1711-1722
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Enhanced validation
- Submitted by
- Atlas Antibodies (provider)
- Enhanced method
- Genetic validation
- Main image
- Experimental details
- Western blot analysis in U-138MG cells transfected with control siRNA, target specific siRNA probe #1 and #2, using Anti-KIAA1462 antibody. Remaining relative intensity is presented. Loading control: Anti-GAPDH.
- Sample type
- Human
- Protocol
- Protocol
Supportive validation
- Submitted by
- Atlas Antibodies (provider)
- Enhanced method
- Orthogonal validation
- Main image
- Experimental details
- Immunohistochemistry analysis in human placenta and liver tissues using HPA017956 antibody. Corresponding KIAA1462 RNA-seq data are presented for the same tissues.
- Sample type
- Human
- Protocol
- Protocol