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- Antigen structure
- References [92]
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- Immunoprecipitation [1]
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- Product number
- 16971-1-AP - Provider product page
- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#16971-1-AP, RRID:AB_2278881
- Product name
- GAP43 antibody
- Antibody type
- Polyclonal
- Description
- GAP43 antibody (Cat. #16971-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse, rat and has been validated for the following applications: IHC, IP, WB,ELISA.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references Obacunone Promotes Functional Recovery After Spinal Cord Injury by Attenuating Neuroinflammation by Targeting the TLR4/MyD88/p38 MAPK Pathway.
Lactate drive M2 polarization via OXPHOS and Cebpb and accelerate peripheral nerve regeneration.
Bioprinting of live platelet-loaded nerve conduit using energy-dissipative hydrogel.
Discovery of Novel Pyrano[3,2-a]carbazole Alkaloid Derivatives against Ischemic Stroke by Targeting ADGRL3.
Inhibition of USP7 destabilizes the noncanonical PRC1.1 complex and induces neuroblastoma differentiation.
The GAP43/RAC1 axis drives glycolytic reprogramming and progression in lung adenocarcinoma.
Copper depletion ameliorates neuronal damage after intracerebral hemorrhage.
ROCK inhibition promotes axon and myelin regeneration via PI3K/Akt/GSK3β in a mouse sciatic nerve injury model.
Simulated microgravity affects neuronal synaptic plasticity by regulating microglial pro-inflammatory activation.
Multidimensional Oriented Piezoelectric Conduits for Peripheral Nerve Defect Regeneration.
Improving neuronal recovery in spinal cord injury with NEP1-40-modified neural stem cells through RhoA/ROCK signaling pathway modulation.
Inhibition of SIRT1/PGC-1α Axis Exacerbates Fluorine and Aluminium Induced Neurotoxicity via Drp1-dependent Aggravated Mitochondrial Fission.
Glycoprotein 130 improves repressor element‑1 silencing transcription factor‑related axon regenerative capacity in peripheral nerves with aging.
Distinct In Vitro Differentiation Protocols Differentially Affect Cytotoxicity Induced by Heavy Metals in Human Neuroblastoma SH-SY5Y Cells.
Muscone enhances synaptic function in vascular dementia through activating BDNF-TrkB-NP2 signaling pathway.
Hydrogel system with growth cone-targeted hydroxyapatite nanorods: Regulating calcium signals for peripheral nerve injury repair.
Lipidomics Analysis Reveals the Effects of Docosahexaenoic Acid from Different Sources on Prefrontal-Cortex Synaptic Plasticity.
Hydrogel loaded with cerium-manganese nanoparticles and nerve growth factor enhances spinal cord injury repair by modulating immune microenvironment and promoting neuronal regeneration.
Hyaluronidase-responsive hydrogel loaded with magnetic nanoparticles combined with external magnetic stimulation for spinal cord injury repair.
Stellate Ganglionectomy Attenuates Pressure Overload-Induced Cardiac Hypertrophy and Dysfunction.
Transcranial alternating current stimulation inhibits ferroptosis and promotes functional recovery in spinal cord injury via the cGMP-PKG signalling pathway.
Engineered BMSC-derived exosomes deliver miR-17-5p inhibitor to restore sensory conduction via the IL-11/GP130/STAT3/GAP-43 axis in dorsal column lesion.
Regulation of nuclear transport of the transcriptional factor REST improves axon regeneration in peripheral nerves.
Clinically Inspired Multimodal Treatment Using Induced Neural Stem Cells-Derived Exosomes Promotes Recovery of Traumatic Brain Injury through Microglial Modulation.
TAK-242 attenuates NLRP3-ASC inflammasome-mediated neuroinflammation via TLR4/NF-κB pathway in rat experimental autoimmune neuritis.
Irisflorentin improves functional recovery after spinal cord injury by protecting the blood-spinal cord barrier and promoting axonal growth.
Occlusal disharmony promotes anxiety-like behaviours by suppressing Sirt1.
Advanced paternal age exacerbates neuroinflammation in offspring via m6A modification-mediated intergenerational inheritance.
Effects of transcranial magnetic stimulation on axonal regeneration in the corticospinal tract of female rats with spinal cord injury.
Inhibition of sympathetic tone via hypothalamic descending pathway propagates glucocorticoid-induced endothelial impairment and osteonecrosis of the femoral head.
Lentivirus-mediated Knockdown of Ski Improves Neurological Function After Spinal Cord Injury in Rats.
Effects on Synaptic Plasticity Markers in Fetal Mice and HT22 Neurons upon F-53B Exposure: The Role of PKA Cytoplasmic Retention.
A peptide against the N-terminus of myristoylated alanine-rich C kinase substrate promotes neuronal differentiation in SH-SY5Y human neuroblastoma cells.
Pulsed electromagnetic field-assisted reduced graphene oxide composite 3D printed nerve scaffold promotes sciatic nerve regeneration in rats.
The role of the sensory input intervention in recovery of the motor function in hypoxic ischemic encephalopathy rat model.
Ginsenoside Rg1 promotes neurite growth of retinal ganglion cells through cAMP/PKA/CREB pathways.
Volatile oil of Angelica sinensis Radix improves cognitive function by inhibiting miR-301a-3p targeting Ppp2ca in cerebral ischemia mice.
GIP attenuates neuronal oxidative stress by regulating glucose uptake in spinal cord injury of rat.
Local Delivery of Dual Stem Cell-Derived Exosomes Using an Electrospun Nanofibrous Platform for the Treatment of Traumatic Brain Injury.
Identification of key regulatory genes involved in myelination after spinal cord injury by GSEA analysis.
Tong-Qiao-Huo-Xue Decoction promotes synaptic remodeling via cAMP/PKA/CREB pathway in vascular dementia rats.
Protective role of TRPV2 in synaptic plasticity through the ERK1/2-CREB-BDNF pathway in chronic unpredictable mild stress rats.
Natural product P57 induces hypothermia through targeting pyridoxal kinase.
Long-term iTBS Improves Neural Functional Recovery by Reducing the Inflammatory Response and Inhibiting Neuronal Apoptosis Via miR-34c-5p/p53/Bax Signaling Pathway in Cerebral Ischemic Rats.
Ketamine counteracts sevoflurane-induced depressive-like behavior and synaptic plasticity impairments through the adenosine A2A receptor/ERK pathway in rats.
Early life exposure to F-53B induces neurobehavioral changes in developing children and disturbs dopamine-dependent synaptic signaling in weaning mice.
Hypoxic preconditioned MSCs-derived small extracellular vesicles for photoreceptor protection in retinal degeneration.
Fidgetin impacts axonal growth and branching in a local mTOR signal dependent manner.
SCG10 is required for peripheral axon maintenance and regeneration in mice.
Tocilizumab promotes repair of spinal cord injury by facilitating the restoration of tight junctions between vascular endothelial cells.
MiR-29c Inhibits TNF-α-Induced ROS Production and Apoptosis in Mouse Hippocampal HT22 Cell Line.
Ginsenoside Rb1 protects hippocampal neurons in depressed rats based on mitophagy-regulated astrocytic pyroptosis.
Oncostatin M's Involvement in the Pathogenesis of Chronic Rhinosinusitis: Focus on Type 1 and 2 Inflammation.
Biodegradable nano black phosphorus based SDF1-α delivery system ameliorates Erectile Dysfunction in a cavernous nerve injury rat model by recruiting endogenous stem/progenitor cells.
Sirt1 Overexpression Inhibits Fibrous Scar Formation and Improves Functional Recovery After Cerebral Ischemic Injury Through the Deacetylation of 14-3-3ζ.
Exosomes-loaded electroconductive nerve dressing for nerve regeneration and pain relief against diabetic peripheral nerve injury.
Ropivacaine microsphere-loaded electroconductive nerve dressings for long-acting analgesia and functional recovery following diabetic peripheral nerve injury.
Evaluation of BDE-47-induced neurodevelopmental toxicity in zebrafish embryos.
A comprehensive mouse brain acetylome-the cellular-specific distribution of acetylated brain proteins.
Hypoxia-pretreated mesenchymal stem cell-derived exosomes-loaded low-temperature extrusion 3D-printed implants for neural regeneration after traumatic brain injury in canines.
Imatinib inhibits pericyte-fibroblast transition and inflammation and promotes axon regeneration by blocking the PDGF-BB/PDGFRβ pathway in spinal cord injury.
Combined cell grafting and VPA administration facilitates neural repair through axonal regeneration and synaptogenesis in traumatic brain injury.
A Class I HDAC Inhibitor BG45 Alleviates Cognitive Impairment through the CaMKII/ITPKA/Ca(2+) Signaling Pathway.
The Cytoskeleton Effectors Rho-Kinase (ROCK) and Mammalian Diaphanous-Related (mDia) Formin Have Dynamic Roles in Tumor Microtube Formation in Invasive Glioblastoma Cells.
Overexpression of NNMT in Glioma Aggravates Tumor Cell Progression: An Emerging Therapeutic Target.
Combined exposure of lead and high-fat diet enhanced cognitive decline via interacting with CREB-BDNF signaling in male rats.
Neuroprotective Effects of Omentin-1 Against Cerebral Hypoxia/Reoxygenation Injury via Activating GAS6/Axl Signaling Pathway in Neuroblastoma Cells.
Vagus Nerve Stimulation in Early Stage of Acute Myocardial Infarction Prevent Ventricular Arrhythmias and Cardiac Remodeling.
Combined Use of Chitosan and Olfactory Mucosa Mesenchymal Stem/Stromal Cells to Promote Peripheral Nerve Regeneration In Vivo.
L-leucine promotes axonal outgrowth and regeneration via mTOR activation.
Brief inhalation of sevoflurane can reduce glial scar formation after hypoxic-ischemic brain injury in neonatal rats.
A Novel Rat Model with Long Range Optic Nerve Injury to Study Retinal Ganglion Cells Endogenous Regeneration.
The vascularization, innervation and myogenesis of early regenerated tail in Gekko japonicus.
Repair of spinal cord injury in rats via exosomes from bone mesenchymal stem cells requires sonic hedgehog.
Enriched environment remedies cognitive dysfunctions and synaptic plasticity through NMDAR-Ca(2+)-Activin A circuit in chronic cerebral hypoperfusion rats.
Tanshinone IIA Promotes Axonal Regeneration in Rats with Focal Cerebral Ischemia Through the Inhibition of Nogo-A/NgR1/RhoA/ROCKII/MLC Signaling.
Sevoflurane leads to learning and memory dysfunction via breaking the balance of tPA/PAI-1.
Ligusticum chuanxiong exerts neuroprotection by promoting adult neurogenesis and inhibiting inflammation in the hippocampus of ME cerebral ischemia rats.
Maternal Treadmill Exercise Reduces the Neurotoxicity of Prenatal Sevoflurane Exposure in Rats via Activation of p300 Histone Acetyltransferase.
Neurotoxicity and biomarkers of zinc oxide nanoparticles in main functional brain regions and dopaminergic neurons.
Human recombinant erythropoietin improves motor function in rats with spinal cord compression-induced cervical myelopathy.
Catalpol improves axonal outgrowth and reinnervation of injured sciatic nerve by activating Akt/mTOR pathway and regulating BDNF and PTEN expression.
Catalpol Exerts a Neuroprotective Effect in the MPTP Mouse Model of Parkinson's Disease.
Combinatory FK506 and Minocycline Treatment Alleviates Prion-Induced Neurodegenerative Events via Caspase-Mediated MAPK-NRF2 Pathway.
Protective effects of astaxanthin on subarachnoid hemorrhage-induced early brain injury: Reduction of cerebral vasospasm and improvement of neuron survival and mitochondrial function.
Catalpol induces cell activity to promote axonal regeneration via the PI3K/AKT/mTOR pathway in vivo and in vitro stroke model.
Effects of Sevoflurane Exposure During Mid-Pregnancy on Learning and Memory in Offspring Rats: Beneficial Effects of Maternal Exercise.
Runx2 was Correlated with Neurite Outgrowth and Schwann Cell Differentiation, Migration After Sciatic Nerve Crush.
An Important Function of Petrosiol E in Inducing the Differentiation of Neuronal Progenitors and in Protecting Them against Oxidative Stress.
Metastasis suppressor 1 regulates neurite outgrowth in primary neuron cultures.
β-Caryophyllene protects in vitro neurovascular unit against oxygen-glucose deprivation and re-oxygenation-induced injury.
Bone marrow mesenchymal stem cells repair spinal cord ischemia/reperfusion injury by promoting axonal growth and anti-autophagy.
Kuang W, Zhang M, Zhang J, Huang H, Chen Q, Yu C, Peng B, Sun W, Lin J, Cheng J, Zhu L
Drug design, development and therapy 2026;20:577707
Drug design, development and therapy 2026;20:577707
Lactate drive M2 polarization via OXPHOS and Cebpb and accelerate peripheral nerve regeneration.
Li W, Wang X, Liu X, Wang L, Liang J, Cui Y, Liu Y, Zhou M, Yang Z, Song M, Yang Y, Zhang L, Zhang B
International immunopharmacology 2026 May 1;176:116474
International immunopharmacology 2026 May 1;176:116474
Bioprinting of live platelet-loaded nerve conduit using energy-dissipative hydrogel.
Zhang J, Wu W, Ren Y, Dai X, Ye S, Zhao W, Liu H, He L, Li B, Zhang L, Luo X, Li W, Zhang X, Yang S, Gou M
Bioactive materials 2026 Mar;57:616-631
Bioactive materials 2026 Mar;57:616-631
Discovery of Novel Pyrano[3,2-a]carbazole Alkaloid Derivatives against Ischemic Stroke by Targeting ADGRL3.
Tao A, Lin Y, Feng J, Luo H, Qu K, Kang Y, Yu H, Chuangjun L, Ma J, Huang W, Sheng L, Zhang D, Zang Y, Peng Y
Journal of medicinal chemistry 2026 Mar 26;69(6):7012-7031
Journal of medicinal chemistry 2026 Mar 26;69(6):7012-7031
Inhibition of USP7 destabilizes the noncanonical PRC1.1 complex and induces neuroblastoma differentiation.
Cmarik EA, Wahi A, Chandekar SS, Otchere SK, Sturgis JE, Salhotra S, Basanthakumar AT, Boyd NX, DiGiovanni G, Zhu H, Alexe G, Schaefer DA, Liu X, Marto JA, Buhrlage SJ, Stegmaier K, Mabe NW
Molecular cancer research : MCR 2026 Mar 19;
Molecular cancer research : MCR 2026 Mar 19;
The GAP43/RAC1 axis drives glycolytic reprogramming and progression in lung adenocarcinoma.
Li K, Shen C, Li Y, Zhang Q, Guo J
Respiratory research 2026 Mar 18;27(1)
Respiratory research 2026 Mar 18;27(1)
Copper depletion ameliorates neuronal damage after intracerebral hemorrhage.
Zhang W, Wu G, Wang L, Ren S
Neurochemistry international 2026 Jun;196:106150
Neurochemistry international 2026 Jun;196:106150
ROCK inhibition promotes axon and myelin regeneration via PI3K/Akt/GSK3β in a mouse sciatic nerve injury model.
Dou S, Li Z, Zheng B, Ren Z, Wang H, Zuo Q, Fang F, Zhuang Y
International journal of molecular medicine 2026 Jan;57(1)
International journal of molecular medicine 2026 Jan;57(1)
Simulated microgravity affects neuronal synaptic plasticity by regulating microglial pro-inflammatory activation.
Chen X, Yuan C, Li Z, Zhao T, Yang Y, Wang Y, Qiao C, Liu Z, Li X
NPJ microgravity 2026 Feb 26;12(1)
NPJ microgravity 2026 Feb 26;12(1)
Multidimensional Oriented Piezoelectric Conduits for Peripheral Nerve Defect Regeneration.
Qi T, Wang X, Wu L, Han M, Zhou C, Wu B, Pei X, He C
Small (Weinheim an der Bergstrasse, Germany) 2026 Apr;22(22):e14376
Small (Weinheim an der Bergstrasse, Germany) 2026 Apr;22(22):e14376
Improving neuronal recovery in spinal cord injury with NEP1-40-modified neural stem cells through RhoA/ROCK signaling pathway modulation.
Gu W, Zhang X, Yuan X, Cao D, Zhao H, Hu J, Yuan H
Biochimica et biophysica acta. Molecular basis of disease 2025 Oct;1871(7):167929
Biochimica et biophysica acta. Molecular basis of disease 2025 Oct;1871(7):167929
Inhibition of SIRT1/PGC-1α Axis Exacerbates Fluorine and Aluminium Induced Neurotoxicity via Drp1-dependent Aggravated Mitochondrial Fission.
Yang L, Qian X, Jiang H, Xie C
Molecular neurobiology 2025 Nov 26;63(1):177
Molecular neurobiology 2025 Nov 26;63(1):177
Glycoprotein 130 improves repressor element‑1 silencing transcription factor‑related axon regenerative capacity in peripheral nerves with aging.
Kawakita S, Naito K, Kubota D, Ueno Y, Negishi-Koga T, Yamamoto Y, Suzuki T, Imazu N, Kawamura K, Hattori N, Ishijima M
Molecular medicine reports 2025 May;31(5)
Molecular medicine reports 2025 May;31(5)
Distinct In Vitro Differentiation Protocols Differentially Affect Cytotoxicity Induced by Heavy Metals in Human Neuroblastoma SH-SY5Y Cells.
Ferdous J, Naitou K, Shiraishi M
Biological trace element research 2025 May;203(5):2595-2605
Biological trace element research 2025 May;203(5):2595-2605
Muscone enhances synaptic function in vascular dementia through activating BDNF-TrkB-NP2 signaling pathway.
Huang P, Sun H, Chen Y, Li J, Peng Y, Ge C, Zhu K, Zhou X, Chang D, Wang N
International immunopharmacology 2025 Mar 6;149:114232
International immunopharmacology 2025 Mar 6;149:114232
Hydrogel system with growth cone-targeted hydroxyapatite nanorods: Regulating calcium signals for peripheral nerve injury repair.
Li Z, Tang X, Yang H, Lu L, Zhang J, Liu Y
Acta biomaterialia 2025 Jul 1;201:171-186
Acta biomaterialia 2025 Jul 1;201:171-186
Lipidomics Analysis Reveals the Effects of Docosahexaenoic Acid from Different Sources on Prefrontal-Cortex Synaptic Plasticity.
He Z, Xiong W, Yang Y, Zhang Y, Li B, Wang F, Li Y, Wang R, Sun Y
Nutrients 2025 Jan 27;17(3)
Nutrients 2025 Jan 27;17(3)
Hydrogel loaded with cerium-manganese nanoparticles and nerve growth factor enhances spinal cord injury repair by modulating immune microenvironment and promoting neuronal regeneration.
Gong Z, Chen Z, Li D, Lu X, Wu J, Sun H, Wang X, Liu S, Xia X, Lu F, Jiang J, Sun C, Wang H, Zeng F, Ma X
Journal of nanobiotechnology 2025 Jan 20;23(1):29
Journal of nanobiotechnology 2025 Jan 20;23(1):29
Hyaluronidase-responsive hydrogel loaded with magnetic nanoparticles combined with external magnetic stimulation for spinal cord injury repair.
Fan Z, Zhang G, Zhan W, Wang J, Wang C, Yue Q, Huang Z, Wang Y
Materials today. Bio 2025 Feb;30:101378
Materials today. Bio 2025 Feb;30:101378
Stellate Ganglionectomy Attenuates Pressure Overload-Induced Cardiac Hypertrophy and Dysfunction.
Yan H, Li X, Liu B, Wu B, Chen C, He L, Wu G
Frontiers in bioscience (Landmark edition) 2025 Feb 19;30(2):26268
Frontiers in bioscience (Landmark edition) 2025 Feb 19;30(2):26268
Transcranial alternating current stimulation inhibits ferroptosis and promotes functional recovery in spinal cord injury via the cGMP-PKG signalling pathway.
Huang K, Fang J, Xiao S, Wang W, Zhang G, Sun W, Shuai L, Bi H
Life sciences 2025 Feb 1;362:123341
Life sciences 2025 Feb 1;362:123341
Engineered BMSC-derived exosomes deliver miR-17-5p inhibitor to restore sensory conduction via the IL-11/GP130/STAT3/GAP-43 axis in dorsal column lesion.
Wang Z, Zhang M, Wang F, Wang X, Song X, Wang X, Zhang L, Ren L, Jing X, Yang L, Wang T
International journal of biological macromolecules 2025 Dec;334(Pt 1):148958
International journal of biological macromolecules 2025 Dec;334(Pt 1):148958
Regulation of nuclear transport of the transcriptional factor REST improves axon regeneration in peripheral nerves.
Suzuki T, Naito K, Kubota D, Ueno Y, Negishi-Koga T, Yamamoto Y, Kawakita S, Imazu N, Kawamura K, Hattori N, Ishijima M
Molecular medicine reports 2025 Dec;32(6)
Molecular medicine reports 2025 Dec;32(6)
Clinically Inspired Multimodal Treatment Using Induced Neural Stem Cells-Derived Exosomes Promotes Recovery of Traumatic Brain Injury through Microglial Modulation.
Li J, Xu M, Cai B, Li X, Liang Z, Xia X, Zhang H, Zhang Z, Tan F, Zheng JC
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2025 Dec;12(46):e08574
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2025 Dec;12(46):e08574
TAK-242 attenuates NLRP3-ASC inflammasome-mediated neuroinflammation via TLR4/NF-κB pathway in rat experimental autoimmune neuritis.
Li X, Yang L, Kang X, Wang G, Yuan Y, Yang H, Yang T, Wang Z
International immunopharmacology 2025 Apr 24;153:114429
International immunopharmacology 2025 Apr 24;153:114429
Irisflorentin improves functional recovery after spinal cord injury by protecting the blood-spinal cord barrier and promoting axonal growth.
Hu Z, Tan H, Zhang Y, Qi T, Li Y, Li N, Zhou Z, Wang Y, Wang H, Zhang H, Wang Q
Experimental neurology 2024 Sep;379:114886
Experimental neurology 2024 Sep;379:114886
Occlusal disharmony promotes anxiety-like behaviours by suppressing Sirt1.
Wu L, Zhang S, Zhang M, Ou Y, Chen J
Clinical oral investigations 2024 Sep 14;28(10):526
Clinical oral investigations 2024 Sep 14;28(10):526
Advanced paternal age exacerbates neuroinflammation in offspring via m6A modification-mediated intergenerational inheritance.
Mao Y, Meng Y, Zou K, Qin N, Wang Y, Yan J, Chen P, Cheng Y, Shi W, Zhou C, Chen H, Sheng J, Liu X, Pan J, Huang H
Journal of neuroinflammation 2024 Oct 4;21(1):249
Journal of neuroinflammation 2024 Oct 4;21(1):249
Effects of transcranial magnetic stimulation on axonal regeneration in the corticospinal tract of female rats with spinal cord injury.
Hu M, Tang Z, Li H, Lei Q, Xu Q, Su J, Huang Y, Chen S, Chen H
Journal of neuroscience methods 2024 Nov;411:110267
Journal of neuroscience methods 2024 Nov;411:110267
Inhibition of sympathetic tone via hypothalamic descending pathway propagates glucocorticoid-induced endothelial impairment and osteonecrosis of the femoral head.
Shao W, Wang B, Wang P, Zhang S, Gong S, Guo X, Duan D, Shao Z, Liu W, He L, Gao F, Lv X, Feng Y
Bone research 2024 Nov 8;12(1):64
Bone research 2024 Nov 8;12(1):64
Lentivirus-mediated Knockdown of Ski Improves Neurological Function After Spinal Cord Injury in Rats.
Wang ZQ, Ran R, Ma CW, Zhao GH, Zhou KS, Zhang HH
Neurochemical research 2024 Nov 16;50(1):15
Neurochemical research 2024 Nov 16;50(1):15
Effects on Synaptic Plasticity Markers in Fetal Mice and HT22 Neurons upon F-53B Exposure: The Role of PKA Cytoplasmic Retention.
Li SP, Zeng HX, Qin SJ, Li QQ, Wu LY, Wu QZ, Lin LZ, Dong GH, Zeng XW
Environment & health (Washington, D.C.) 2024 Nov 15;2(11):776-785
Environment & health (Washington, D.C.) 2024 Nov 15;2(11):776-785
A peptide against the N-terminus of myristoylated alanine-rich C kinase substrate promotes neuronal differentiation in SH-SY5Y human neuroblastoma cells.
Ferdous J, Naitou K, Shiraishi M
The Journal of veterinary medical science 2024 Nov 1;86(11):1136-1144
The Journal of veterinary medical science 2024 Nov 1;86(11):1136-1144
Pulsed electromagnetic field-assisted reduced graphene oxide composite 3D printed nerve scaffold promotes sciatic nerve regeneration in rats.
Wang Z, Li S, Wu Z, Kang Y, Xie S, Cai Z, Shan X, Li Q
Biofabrication 2024 May 7;16(3)
Biofabrication 2024 May 7;16(3)
The role of the sensory input intervention in recovery of the motor function in hypoxic ischemic encephalopathy rat model.
Dong J, Dong Y, An L, Wang Y, Li Y, Jin L
Journal of neurophysiology 2024 May 1;131(5):865-871
Journal of neurophysiology 2024 May 1;131(5):865-871
Ginsenoside Rg1 promotes neurite growth of retinal ganglion cells through cAMP/PKA/CREB pathways.
Jiang YY, Wei RY, Tang K, Wang Z, Tan NH
Journal of ginseng research 2024 Mar;48(2):163-170
Journal of ginseng research 2024 Mar;48(2):163-170
Volatile oil of Angelica sinensis Radix improves cognitive function by inhibiting miR-301a-3p targeting Ppp2ca in cerebral ischemia mice.
Zhao J, Luo J, Deng C, Fan Y, Liu N, Cao J, Chen D, Diao Y
Journal of ethnopharmacology 2024 Mar 25;322:117621
Journal of ethnopharmacology 2024 Mar 25;322:117621
GIP attenuates neuronal oxidative stress by regulating glucose uptake in spinal cord injury of rat.
Guo B, Qi M, Luo X, Guo L, Xu M, Zhang Y, Li Z, Li M, Wu R, Guan T, Liu M, Liu Y
CNS neuroscience & therapeutics 2024 Jun;30(6):e14806
CNS neuroscience & therapeutics 2024 Jun;30(6):e14806
Local Delivery of Dual Stem Cell-Derived Exosomes Using an Electrospun Nanofibrous Platform for the Treatment of Traumatic Brain Injury.
Li J, Li X, Li X, Liang Z, Wang Z, Shahzad KA, Xu M, Tan F
ACS applied materials & interfaces 2024 Jul 24;16(29):37497-37512
ACS applied materials & interfaces 2024 Jul 24;16(29):37497-37512
Identification of key regulatory genes involved in myelination after spinal cord injury by GSEA analysis.
Lv Y, Ji L, Dai H, Qiu S, Wang Y, Teng C, Yu B, Mi D, Yao C
Experimental neurology 2024 Dec;382:114966
Experimental neurology 2024 Dec;382:114966
Tong-Qiao-Huo-Xue Decoction promotes synaptic remodeling via cAMP/PKA/CREB pathway in vascular dementia rats.
Li J, Ye H, Xu F, Yang Y, Ge C, Yao M, Huang P, Wang L, Wang N, Zhou X, Chang D
Phytomedicine : international journal of phytotherapy and phytopharmacology 2024 Dec;135:156166
Phytomedicine : international journal of phytotherapy and phytopharmacology 2024 Dec;135:156166
Protective role of TRPV2 in synaptic plasticity through the ERK1/2-CREB-BDNF pathway in chronic unpredictable mild stress rats.
Zhou Y, Cong T, Chen J, Chu Z, Sun Y, Zhao D, Chen X, Li L, Liu Y, Cheng J, Li Q, Yin S, Xiao Z
Biochemical and biophysical research communications 2024 Aug 20;721:150128
Biochemical and biophysical research communications 2024 Aug 20;721:150128
Natural product P57 induces hypothermia through targeting pyridoxal kinase.
Wang R, Xiao L, Pan J, Bao G, Zhu Y, Zhu D, Wang J, Pei C, Ma Q, Fu X, Wang Z, Zhu M, Wang G, Gong L, Tong Q, Jiang M, Hu J, He M, Wang Y, Li T, Liang C, Li W, Xia C, Li Z, Ma DK, Tan M, Liu JY, Jiang W, Luo C, Yu B, Dang Y
Nature communications 2023 Sep 26;14(1):5984
Nature communications 2023 Sep 26;14(1):5984
Long-term iTBS Improves Neural Functional Recovery by Reducing the Inflammatory Response and Inhibiting Neuronal Apoptosis Via miR-34c-5p/p53/Bax Signaling Pathway in Cerebral Ischemic Rats.
Hu S, Wang X, Yang X, Ouyang S, Pan X, Fu Y, Wu S
Neuroscience 2023 Sep 1;527:37-51
Neuroscience 2023 Sep 1;527:37-51
Ketamine counteracts sevoflurane-induced depressive-like behavior and synaptic plasticity impairments through the adenosine A2A receptor/ERK pathway in rats.
Yu W, Wu Z, Li X, Ding M, Xu Y, Zhao P
Molecular neurobiology 2023 Nov;60(11):6160-6175
Molecular neurobiology 2023 Nov;60(11):6160-6175
Early life exposure to F-53B induces neurobehavioral changes in developing children and disturbs dopamine-dependent synaptic signaling in weaning mice.
Liang LX, Liang J, Li QQ, Zeeshan M, Zhang Z, Jin N, Lin LZ, Wu LY, Sun MK, Tan WH, Zhou Y, Chu C, Hu LW, Liu RQ, Zeng XW, Yu Y, Dong GH
Environment international 2023 Nov;181:108272
Environment international 2023 Nov;181:108272
Hypoxic preconditioned MSCs-derived small extracellular vesicles for photoreceptor protection in retinal degeneration.
Sun Y, Sun Y, Chen S, Yu Y, Ma Y, Sun F
Journal of nanobiotechnology 2023 Nov 25;21(1):449
Journal of nanobiotechnology 2023 Nov 25;21(1):449
Fidgetin impacts axonal growth and branching in a local mTOR signal dependent manner.
Ma C, Wang J, Tu Q, Wu R, Lai X, Lin G, Dong Z, Guan T, Qiang L, Liu Y, Liu M
Experimental neurology 2023 Mar;361:114315
Experimental neurology 2023 Mar;361:114315
SCG10 is required for peripheral axon maintenance and regeneration in mice.
Li Y, Tian Y, Pei X, Zheng P, Miao L, Li L, Luo C, Zhang P, Jiang B, Teng J, Huang N, Chen J
Journal of cell science 2023 Jun 15;136(12)
Journal of cell science 2023 Jun 15;136(12)
Tocilizumab promotes repair of spinal cord injury by facilitating the restoration of tight junctions between vascular endothelial cells.
Luo Y, Yao F, Shi Y, Zhu Z, Xiao Z, You X, Liu Y, Yu S, Tian D, Cheng L, Zheng M, Jing J
Fluids and barriers of the CNS 2023 Jan 9;20(1):1
Fluids and barriers of the CNS 2023 Jan 9;20(1):1
MiR-29c Inhibits TNF-α-Induced ROS Production and Apoptosis in Mouse Hippocampal HT22 Cell Line.
Li B, Lu Y, Wang R, Xu T, Lei X, Jin H, Gao X, Xie Y, Liu X, Zeng J
Neurochemical research 2023 Feb;48(2):519-536
Neurochemical research 2023 Feb;48(2):519-536
Ginsenoside Rb1 protects hippocampal neurons in depressed rats based on mitophagy-regulated astrocytic pyroptosis.
Li Y, Li J, Yang L, Ren F, Dong K, Zhao Z, Duan W, Wei W, Guo R
Phytomedicine : international journal of phytotherapy and phytopharmacology 2023 Dec;121:155083
Phytomedicine : international journal of phytotherapy and phytopharmacology 2023 Dec;121:155083
Oncostatin M's Involvement in the Pathogenesis of Chronic Rhinosinusitis: Focus on Type 1 and 2 Inflammation.
Ishikawa C, Takeno S, Okamoto Y, Kawasumi T, Kakimoto T, Takemoto K, Nishida M, Ishino T, Hamamoto T, Ueda T, Tanaka A
Biomedicines 2023 Dec 5;11(12)
Biomedicines 2023 Dec 5;11(12)
Biodegradable nano black phosphorus based SDF1-α delivery system ameliorates Erectile Dysfunction in a cavernous nerve injury rat model by recruiting endogenous stem/progenitor cells.
Fu Q, Song L, Li J, Yi B, Huang Y, Zhang Z, Xin Z, Zhu J
Journal of nanobiotechnology 2023 Dec 18;21(1):487
Journal of nanobiotechnology 2023 Dec 18;21(1):487
Sirt1 Overexpression Inhibits Fibrous Scar Formation and Improves Functional Recovery After Cerebral Ischemic Injury Through the Deacetylation of 14-3-3ζ.
Chen Y, Huang J, Liu J, Zhu H, Li X, Wen J, Tian M, Ren J, Zhou L, Yang Q
Molecular neurobiology 2023 Aug;60(8):4795-4810
Molecular neurobiology 2023 Aug;60(8):4795-4810
Exosomes-loaded electroconductive nerve dressing for nerve regeneration and pain relief against diabetic peripheral nerve injury.
Yang Q, Su S, Liu S, Yang S, Xu J, Zhong Y, Yang Y, Tian L, Tan Z, Wang J, Yu Z, Shi Z, Liang F
Bioactive materials 2023 Aug;26:194-215
Bioactive materials 2023 Aug;26:194-215
Ropivacaine microsphere-loaded electroconductive nerve dressings for long-acting analgesia and functional recovery following diabetic peripheral nerve injury.
Liang F, Yang Y, Chen Y, Xie J, Liu S, Tan Z, Tian L, Yu Z, Shi Z, Xie P, Ding H, Yang Q
Materials today. Bio 2023 Aug;21:100712
Materials today. Bio 2023 Aug;21:100712
Evaluation of BDE-47-induced neurodevelopmental toxicity in zebrafish embryos.
Zhuang J, Pan ZJ, Qin Y, Liang H, Zhang WF, Sun ZY, Shi HB
Environmental science and pollution research international 2023 Apr;30(18):54022-54034
Environmental science and pollution research international 2023 Apr;30(18):54022-54034
A comprehensive mouse brain acetylome-the cellular-specific distribution of acetylated brain proteins.
Ji Y, Chen Z, Cen Z, Ye Y, Li S, Lu X, Shao Q, Wang D, Ji J, Ji Q
Frontiers in cellular neuroscience 2022;16:980815
Frontiers in cellular neuroscience 2022;16:980815
Hypoxia-pretreated mesenchymal stem cell-derived exosomes-loaded low-temperature extrusion 3D-printed implants for neural regeneration after traumatic brain injury in canines.
Liu X, Wang J, Wang P, Zhong L, Wang S, Feng Q, Wei X, Zhou L
Frontiers in bioengineering and biotechnology 2022;10:1025138
Frontiers in bioengineering and biotechnology 2022;10:1025138
Imatinib inhibits pericyte-fibroblast transition and inflammation and promotes axon regeneration by blocking the PDGF-BB/PDGFRβ pathway in spinal cord injury.
Yao F, Luo Y, Liu YC, Chen YH, Li YT, Hu XY, You XY, Yu SS, Li ZY, Chen L, Tian DS, Zheng MG, Cheng L, Jing JH
Inflammation and regeneration 2022 Sep 26;42(1):44
Inflammation and regeneration 2022 Sep 26;42(1):44
Combined cell grafting and VPA administration facilitates neural repair through axonal regeneration and synaptogenesis in traumatic brain injury.
Liu S, Tian H, Niu Y, Yu C, Xie L, Jin Z, Niu W, Ren J, Fu L, Yao Z
Acta biochimica et biophysica Sinica 2022 Sep 25;54(9):1289-1300
Acta biochimica et biophysica Sinica 2022 Sep 25;54(9):1289-1300
A Class I HDAC Inhibitor BG45 Alleviates Cognitive Impairment through the CaMKII/ITPKA/Ca(2+) Signaling Pathway.
Liu J, Zhang C, Wang J, Huang Y, Shen D, Hu Y, Chu H, Yu X, Zhang L, Ma H
Pharmaceuticals (Basel, Switzerland) 2022 Nov 28;15(12)
Pharmaceuticals (Basel, Switzerland) 2022 Nov 28;15(12)
The Cytoskeleton Effectors Rho-Kinase (ROCK) and Mammalian Diaphanous-Related (mDia) Formin Have Dynamic Roles in Tumor Microtube Formation in Invasive Glioblastoma Cells.
Becker KN, Pettee KM, Sugrue A, Reinard KA, Schroeder JL, Eisenmann KM
Cells 2022 May 5;11(9)
Cells 2022 May 5;11(9)
Overexpression of NNMT in Glioma Aggravates Tumor Cell Progression: An Emerging Therapeutic Target.
Sun W, Zou Y, Cai Z, Huang J, Hong X, Liang Q, Jin W
Cancers 2022 Jul 21;14(14)
Cancers 2022 Jul 21;14(14)
Combined exposure of lead and high-fat diet enhanced cognitive decline via interacting with CREB-BDNF signaling in male rats.
Liu R, Bai L, Liu M, Wang R, Wu Y, Li Q, Ba Y, Zhang H, Zhou G, Yu F, Huang H
Environmental pollution (Barking, Essex : 1987) 2022 Jul 1;304:119200
Environmental pollution (Barking, Essex : 1987) 2022 Jul 1;304:119200
Neuroprotective Effects of Omentin-1 Against Cerebral Hypoxia/Reoxygenation Injury via Activating GAS6/Axl Signaling Pathway in Neuroblastoma Cells.
Niu X, Cheng Y, Zhang M, Du L, Wu X, Lu C, Li X, Liu S, Zhao A, Zhang S, Wu Z, Ding B, Shi W, Wang C, Yang Y, Tian Y
Frontiers in cell and developmental biology 2021;9:784035
Frontiers in cell and developmental biology 2021;9:784035
Vagus Nerve Stimulation in Early Stage of Acute Myocardial Infarction Prevent Ventricular Arrhythmias and Cardiac Remodeling.
Zhao S, Dai Y, Ning X, Tang M, Zhao Y, Li Z, Zhang S
Frontiers in cardiovascular medicine 2021;8:648910
Frontiers in cardiovascular medicine 2021;8:648910
Combined Use of Chitosan and Olfactory Mucosa Mesenchymal Stem/Stromal Cells to Promote Peripheral Nerve Regeneration In Vivo.
Alvites RD, Branquinho MV, Sousa AC, Amorim I, Magalhães R, João F, Almeida D, Amado S, Prada J, Pires I, Zen F, Raimondo S, Luís AL, Geuna S, Varejão ASP, Maurício AC
Stem cells international 2021;2021:6613029
Stem cells international 2021;2021:6613029
L-leucine promotes axonal outgrowth and regeneration via mTOR activation.
Ma C, Teng L, Lin G, Guo B, Zhuo R, Qian X, Guan T, Wu R, Liu Y, Liu M
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2021 May;35(5):e21526
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2021 May;35(5):e21526
Brief inhalation of sevoflurane can reduce glial scar formation after hypoxic-ischemic brain injury in neonatal rats.
Gao QS, Zhang YH, Xue H, Wu ZY, Li C, Zhao P
Neural regeneration research 2021 Jun;16(6):1052-1061
Neural regeneration research 2021 Jun;16(6):1052-1061
A Novel Rat Model with Long Range Optic Nerve Injury to Study Retinal Ganglion Cells Endogenous Regeneration.
Zhang S, Liu B, Zhu H, Jin H, Gong Z, Qiu H, Xu M, Chen M, Nan K, Wu W
Neuroscience 2021 Jun 15;465:71-84
Neuroscience 2021 Jun 15;465:71-84
The vascularization, innervation and myogenesis of early regenerated tail in Gekko japonicus.
Liu Z, Huang S, Xu M, Zhang W, Guan T, Wang Q, Liu M, Yao J, Liu Y
Journal of molecular histology 2021 Dec;52(6):1189-1204
Journal of molecular histology 2021 Dec;52(6):1189-1204
Repair of spinal cord injury in rats via exosomes from bone mesenchymal stem cells requires sonic hedgehog.
Jia Y, Yang J, Lu T, Pu X, Chen Q, Ji L, Luo C
Regenerative therapy 2021 Dec;18:309-315
Regenerative therapy 2021 Dec;18:309-315
Enriched environment remedies cognitive dysfunctions and synaptic plasticity through NMDAR-Ca(2+)-Activin A circuit in chronic cerebral hypoperfusion rats.
Zhang X, Shi X, Wang J, Xu Z, He J
Aging 2021 Aug 30;13(16):20748-20761
Aging 2021 Aug 30;13(16):20748-20761
Tanshinone IIA Promotes Axonal Regeneration in Rats with Focal Cerebral Ischemia Through the Inhibition of Nogo-A/NgR1/RhoA/ROCKII/MLC Signaling.
Wang J, Ni G, Liu Y, Han Y, Jia L, Wang Y
Drug design, development and therapy 2020;14:2775-2787
Drug design, development and therapy 2020;14:2775-2787
Sevoflurane leads to learning and memory dysfunction via breaking the balance of tPA/PAI-1.
Dong Y, Hong W, Tang Z, Gao Y, Wu X, Liu H
Neurochemistry international 2020 Oct;139:104789
Neurochemistry international 2020 Oct;139:104789
Ligusticum chuanxiong exerts neuroprotection by promoting adult neurogenesis and inhibiting inflammation in the hippocampus of ME cerebral ischemia rats.
Wang M, Yao M, Liu J, Takagi N, Yang B, Zhang M, Xu L, Ren J, Fan X, Tian F
Journal of ethnopharmacology 2020 Mar 1;249:112385
Journal of ethnopharmacology 2020 Mar 1;249:112385
Maternal Treadmill Exercise Reduces the Neurotoxicity of Prenatal Sevoflurane Exposure in Rats via Activation of p300 Histone Acetyltransferase.
Wu Z, Zhang Y, Yang X, Zhao P
Neurochemical research 2020 Jul;45(7):1626-1635
Neurochemical research 2020 Jul;45(7):1626-1635
Neurotoxicity and biomarkers of zinc oxide nanoparticles in main functional brain regions and dopaminergic neurons.
Liu H, Yang H, Fang Y, Li K, Tian L, Liu X, Zhang W, Tan Y, Lai W, Bian L, Lin B, Xi Z
The Science of the total environment 2020 Feb 25;705:135809
The Science of the total environment 2020 Feb 25;705:135809
Human recombinant erythropoietin improves motor function in rats with spinal cord compression-induced cervical myelopathy.
Tanaka T, Murata H, Miyazaki R, Yoshizumi T, Sato M, Ohtake M, Tateishi K, Kim P, Yamamoto T
PloS one 2019;14(12):e0214351
PloS one 2019;14(12):e0214351
Catalpol improves axonal outgrowth and reinnervation of injured sciatic nerve by activating Akt/mTOR pathway and regulating BDNF and PTEN expression.
Zhu H, Wang Y, Yang X, Wan G, Qiu Y, Ye X, Gao Y, Wan D
American journal of translational research 2019;11(3):1311-1326
American journal of translational research 2019;11(3):1311-1326
Catalpol Exerts a Neuroprotective Effect in the MPTP Mouse Model of Parkinson's Disease.
Wang LY, Yu X, Li XX, Zhao YN, Wang CY, Wang ZY, He ZY
Frontiers in aging neuroscience 2019;11:316
Frontiers in aging neuroscience 2019;11:316
Combinatory FK506 and Minocycline Treatment Alleviates Prion-Induced Neurodegenerative Events via Caspase-Mediated MAPK-NRF2 Pathway.
Shah SZA, Zhao D, Taglialatela G, Hussain T, Dong H, Sabir N, Mangi MH, Wu W, Lai M, Zhang X, Duan Y, Wang L, Zhou X, Yang L
International journal of molecular sciences 2019 Mar 6;20(5)
International journal of molecular sciences 2019 Mar 6;20(5)
Protective effects of astaxanthin on subarachnoid hemorrhage-induced early brain injury: Reduction of cerebral vasospasm and improvement of neuron survival and mitochondrial function.
Wang Y, Liu Y, Li Y, Liu B, Wu P, Xu S, Shi H
Acta histochemica 2019 Jan;121(1):56-63
Acta histochemica 2019 Jan;121(1):56-63
Catalpol induces cell activity to promote axonal regeneration via the PI3K/AKT/mTOR pathway in vivo and in vitro stroke model.
Wang J, Wan D, Wan G, Wang J, Zhang J, Zhu H
Annals of translational medicine 2019 Dec;7(23):756
Annals of translational medicine 2019 Dec;7(23):756
Effects of Sevoflurane Exposure During Mid-Pregnancy on Learning and Memory in Offspring Rats: Beneficial Effects of Maternal Exercise.
Wu Z, Li X, Zhang Y, Tong D, Wang L, Zhao P
Frontiers in cellular neuroscience 2018;12:122
Frontiers in cellular neuroscience 2018;12:122
Runx2 was Correlated with Neurite Outgrowth and Schwann Cell Differentiation, Migration After Sciatic Nerve Crush.
Ding D, Zhang P, Liu Y, Wang Y, Sun W, Yu Z, Cheng Z, Wang Y
Neurochemical research 2018 Dec;43(12):2423-2434
Neurochemical research 2018 Dec;43(12):2423-2434
An Important Function of Petrosiol E in Inducing the Differentiation of Neuronal Progenitors and in Protecting Them against Oxidative Stress.
Liu J, Wang L, Du Y, Liu S
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2017 Oct;4(10):1700089
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2017 Oct;4(10):1700089
Metastasis suppressor 1 regulates neurite outgrowth in primary neuron cultures.
Yu J, Lin S, Wang M, Liang L, Zou Z, Zhou X, Wang M, Chen P, Wang Y
Neuroscience 2016 Oct 1;333:123-31
Neuroscience 2016 Oct 1;333:123-31
β-Caryophyllene protects in vitro neurovascular unit against oxygen-glucose deprivation and re-oxygenation-induced injury.
Tian X, Peng J, Zhong J, Yang M, Pang J, Lou J, Li M, An R, Zhang Q, Xu L, Dong Z
Journal of neurochemistry 2016 Dec;139(5):757-768
Journal of neurochemistry 2016 Dec;139(5):757-768
Bone marrow mesenchymal stem cells repair spinal cord ischemia/reperfusion injury by promoting axonal growth and anti-autophagy.
Yin F, Meng C, Lu R, Li L, Zhang Y, Chen H, Qin Y, Guo L
Neural regeneration research 2014 Sep 15;9(18):1665-71
Neural regeneration research 2014 Sep 15;9(18):1665-71
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Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- mouse brain tissue were subjected to SDS PAGE followed by western blot with 16971-1-AP(GAP43 antibody) at dilution of 1:1200
- Sample type
- tissue
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- IP Result of anti-GAP43 (IP:16971-1-AP, 4ug; Detection:16971-1-AP 1:500) with mouse brain tissue lysate 6000ug.
- Sample type
- tissue
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- The GAP43 antibody from Proteintech is a rabbit polyclonal antibody to a recombinant protein of human GAP43. This antibody recognizes human,mouse,rat antigen. The GAP43 antibody has been validated for the following applications: ELISA, WB, IHC, IP analysis.
