Antibody data
- Antibody Data
- Antigen structure
- References [23]
- Comments [0]
- Validations
- Western blot [1]
- Immunoprecipitation [1]
- Immunohistochemistry [1]
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Validation data
Reference
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- Product number
- 16971-1-AP - Provider product page
- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#16971-1-AP, RRID:AB_2278881
- Product name
- GAP43 antibody
- Antibody type
- Polyclonal
- Description
- GAP43 antibody (Cat. #16971-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse, rat and has been validated for the following applications: IHC, IP, WB,ELISA.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references Vagus Nerve Stimulation in Early Stage of Acute Myocardial Infarction Prevent Ventricular Arrhythmias and Cardiac Remodeling.
Combined Use of Chitosan and Olfactory Mucosa Mesenchymal Stem/Stromal Cells to Promote Peripheral Nerve Regeneration In Vivo.
L-leucine promotes axonal outgrowth and regeneration via mTOR activation.
Brief inhalation of sevoflurane can reduce glial scar formation after hypoxic-ischemic brain injury in neonatal rats.
A Novel Rat Model with Long Range Optic Nerve Injury to Study Retinal Ganglion Cells Endogenous Regeneration.
The vascularization, innervation and myogenesis of early regenerated tail in Gekko japonicus.
Repair of spinal cord injury in rats via exosomes from bone mesenchymal stem cells requires sonic hedgehog.
Enriched environment remedies cognitive dysfunctions and synaptic plasticity through NMDAR-Ca2+-Activin A circuit in chronic cerebral hypoperfusion rats.
Tanshinone IIA Promotes Axonal Regeneration in Rats with Focal Cerebral Ischemia Through the Inhibition of Nogo-A/NgR1/RhoA/ROCKII/MLC Signaling.
Sevoflurane leads to learning and memory dysfunction via breaking the balance of tPA/PAI-1.
Ligusticum chuanxiong exerts neuroprotection by promoting adult neurogenesis and inhibiting inflammation in the hippocampus of ME cerebral ischemia rats.
Neurotoxicity and biomarkers of zinc oxide nanoparticles in main functional brain regions and dopaminergic neurons.
Human recombinant erythropoietin improves motor function in rats with spinal cord compression-induced cervical myelopathy.
Catalpol Exerts a Neuroprotective Effect in the MPTP Mouse Model of Parkinson's Disease.
Combinatory FK506 and Minocycline Treatment Alleviates Prion-Induced Neurodegenerative Events via Caspase-Mediated MAPK-NRF2 Pathway.
Protective effects of astaxanthin on subarachnoid hemorrhage-induced early brain injury: Reduction of cerebral vasospasm and improvement of neuron survival and mitochondrial function.
Catalpol induces cell activity to promote axonal regeneration via the PI3K/AKT/mTOR pathway in vivo and in vitro stroke model.
Effects of Sevoflurane Exposure During Mid-Pregnancy on Learning and Memory in Offspring Rats: Beneficial Effects of Maternal Exercise.
Runx2 was Correlated with Neurite Outgrowth and Schwann Cell Differentiation, Migration After Sciatic Nerve Crush.
An Important Function of Petrosiol E in Inducing the Differentiation of Neuronal Progenitors and in Protecting Them against Oxidative Stress.
Metastasis suppressor 1 regulates neurite outgrowth in primary neuron cultures.
β-Caryophyllene protects in vitro neurovascular unit against oxygen-glucose deprivation and re-oxygenation-induced injury.
Bone marrow mesenchymal stem cells repair spinal cord ischemia/reperfusion injury by promoting axonal growth and anti-autophagy.
Zhao S, Dai Y, Ning X, Tang M, Zhao Y, Li Z, Zhang S
Frontiers in cardiovascular medicine 2021;8:648910
Frontiers in cardiovascular medicine 2021;8:648910
Combined Use of Chitosan and Olfactory Mucosa Mesenchymal Stem/Stromal Cells to Promote Peripheral Nerve Regeneration In Vivo.
Alvites RD, Branquinho MV, Sousa AC, Amorim I, Magalhães R, João F, Almeida D, Amado S, Prada J, Pires I, Zen F, Raimondo S, Luís AL, Geuna S, Varejão ASP, Maurício AC
Stem cells international 2021;2021:6613029
Stem cells international 2021;2021:6613029
L-leucine promotes axonal outgrowth and regeneration via mTOR activation.
Ma C, Teng L, Lin G, Guo B, Zhuo R, Qian X, Guan T, Wu R, Liu Y, Liu M
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2021 May;35(5):e21526
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2021 May;35(5):e21526
Brief inhalation of sevoflurane can reduce glial scar formation after hypoxic-ischemic brain injury in neonatal rats.
Gao QS, Zhang YH, Xue H, Wu ZY, Li C, Zhao P
Neural regeneration research 2021 Jun;16(6):1052-1061
Neural regeneration research 2021 Jun;16(6):1052-1061
A Novel Rat Model with Long Range Optic Nerve Injury to Study Retinal Ganglion Cells Endogenous Regeneration.
Zhang S, Liu B, Zhu H, Jin H, Gong Z, Qiu H, Xu M, Chen M, Nan K, Wu W
Neuroscience 2021 Jun 15;465:71-84
Neuroscience 2021 Jun 15;465:71-84
The vascularization, innervation and myogenesis of early regenerated tail in Gekko japonicus.
Liu Z, Huang S, Xu M, Zhang W, Guan T, Wang Q, Liu M, Yao J, Liu Y
Journal of molecular histology 2021 Dec;52(6):1189-1204
Journal of molecular histology 2021 Dec;52(6):1189-1204
Repair of spinal cord injury in rats via exosomes from bone mesenchymal stem cells requires sonic hedgehog.
Jia Y, Yang J, Lu T, Pu X, Chen Q, Ji L, Luo C
Regenerative therapy 2021 Dec;18:309-315
Regenerative therapy 2021 Dec;18:309-315
Enriched environment remedies cognitive dysfunctions and synaptic plasticity through NMDAR-Ca2+-Activin A circuit in chronic cerebral hypoperfusion rats.
Zhang X, Shi X, Wang J, Xu Z, He J
Aging 2021 Aug 30;13(16):20748-20761
Aging 2021 Aug 30;13(16):20748-20761
Tanshinone IIA Promotes Axonal Regeneration in Rats with Focal Cerebral Ischemia Through the Inhibition of Nogo-A/NgR1/RhoA/ROCKII/MLC Signaling.
Wang J, Ni G, Liu Y, Han Y, Jia L, Wang Y
Drug design, development and therapy 2020;14:2775-2787
Drug design, development and therapy 2020;14:2775-2787
Sevoflurane leads to learning and memory dysfunction via breaking the balance of tPA/PAI-1.
Dong Y, Hong W, Tang Z, Gao Y, Wu X, Liu H
Neurochemistry international 2020 Oct;139:104789
Neurochemistry international 2020 Oct;139:104789
Ligusticum chuanxiong exerts neuroprotection by promoting adult neurogenesis and inhibiting inflammation in the hippocampus of ME cerebral ischemia rats.
Wang M, Yao M, Liu J, Takagi N, Yang B, Zhang M, Xu L, Ren J, Fan X, Tian F
Journal of ethnopharmacology 2020 Mar 1;249:112385
Journal of ethnopharmacology 2020 Mar 1;249:112385
Neurotoxicity and biomarkers of zinc oxide nanoparticles in main functional brain regions and dopaminergic neurons.
Liu H, Yang H, Fang Y, Li K, Tian L, Liu X, Zhang W, Tan Y, Lai W, Bian L, Lin B, Xi Z
The Science of the total environment 2020 Feb 25;705:135809
The Science of the total environment 2020 Feb 25;705:135809
Human recombinant erythropoietin improves motor function in rats with spinal cord compression-induced cervical myelopathy.
Tanaka T, Murata H, Miyazaki R, Yoshizumi T, Sato M, Ohtake M, Tateishi K, Kim P, Yamamoto T
PloS one 2019;14(12):e0214351
PloS one 2019;14(12):e0214351
Catalpol Exerts a Neuroprotective Effect in the MPTP Mouse Model of Parkinson's Disease.
Wang LY, Yu X, Li XX, Zhao YN, Wang CY, Wang ZY, He ZY
Frontiers in aging neuroscience 2019;11:316
Frontiers in aging neuroscience 2019;11:316
Combinatory FK506 and Minocycline Treatment Alleviates Prion-Induced Neurodegenerative Events via Caspase-Mediated MAPK-NRF2 Pathway.
Shah SZA, Zhao D, Taglialatela G, Hussain T, Dong H, Sabir N, Mangi MH, Wu W, Lai M, Zhang X, Duan Y, Wang L, Zhou X, Yang L
International journal of molecular sciences 2019 Mar 6;20(5)
International journal of molecular sciences 2019 Mar 6;20(5)
Protective effects of astaxanthin on subarachnoid hemorrhage-induced early brain injury: Reduction of cerebral vasospasm and improvement of neuron survival and mitochondrial function.
Wang Y, Liu Y, Li Y, Liu B, Wu P, Xu S, Shi H
Acta histochemica 2019 Jan;121(1):56-63
Acta histochemica 2019 Jan;121(1):56-63
Catalpol induces cell activity to promote axonal regeneration via the PI3K/AKT/mTOR pathway in vivo and in vitro stroke model.
Wang J, Wan D, Wan G, Wang J, Zhang J, Zhu H
Annals of translational medicine 2019 Dec;7(23):756
Annals of translational medicine 2019 Dec;7(23):756
Effects of Sevoflurane Exposure During Mid-Pregnancy on Learning and Memory in Offspring Rats: Beneficial Effects of Maternal Exercise.
Wu Z, Li X, Zhang Y, Tong D, Wang L, Zhao P
Frontiers in cellular neuroscience 2018;12:122
Frontiers in cellular neuroscience 2018;12:122
Runx2 was Correlated with Neurite Outgrowth and Schwann Cell Differentiation, Migration After Sciatic Nerve Crush.
Ding D, Zhang P, Liu Y, Wang Y, Sun W, Yu Z, Cheng Z, Wang Y
Neurochemical research 2018 Dec;43(12):2423-2434
Neurochemical research 2018 Dec;43(12):2423-2434
An Important Function of Petrosiol E in Inducing the Differentiation of Neuronal Progenitors and in Protecting Them against Oxidative Stress.
Liu J, Wang L, Du Y, Liu S
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2017 Oct;4(10):1700089
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2017 Oct;4(10):1700089
Metastasis suppressor 1 regulates neurite outgrowth in primary neuron cultures.
Yu J, Lin S, Wang M, Liang L, Zou Z, Zhou X, Wang M, Chen P, Wang Y
Neuroscience 2016 Oct 1;333:123-31
Neuroscience 2016 Oct 1;333:123-31
β-Caryophyllene protects in vitro neurovascular unit against oxygen-glucose deprivation and re-oxygenation-induced injury.
Tian X, Peng J, Zhong J, Yang M, Pang J, Lou J, Li M, An R, Zhang Q, Xu L, Dong Z
Journal of neurochemistry 2016 Dec;139(5):757-768
Journal of neurochemistry 2016 Dec;139(5):757-768
Bone marrow mesenchymal stem cells repair spinal cord ischemia/reperfusion injury by promoting axonal growth and anti-autophagy.
Yin F, Meng C, Lu R, Li L, Zhang Y, Chen H, Qin Y, Guo L
Neural regeneration research 2014 Sep 15;9(18):1665-71
Neural regeneration research 2014 Sep 15;9(18):1665-71
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Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- mouse brain tissue were subjected to SDS PAGE followed by western blot with 16971-1-AP(GAP43 antibody) at dilution of 1:1200
- Sample type
- tissue
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- IP Result of anti-GAP43 (IP:16971-1-AP, 4ug; Detection:16971-1-AP 1:500) with mouse brain tissue lysate 6000ug.
- Sample type
- tissue
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- The GAP43 antibody from Proteintech is a rabbit polyclonal antibody to a recombinant protein of human GAP43. This antibody recognizes human,mouse,rat antigen. The GAP43 antibody has been validated for the following applications: ELISA, WB, IHC, IP analysis.