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Western blot
ImmunocytochemistryAntibody data
- Antibody Data
- Antigen structure
- References [69]
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- Western blot [2]
- Immunohistochemistry [2]
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- Product number
- NB300-143 - Provider product page
- Provider
- Novus Biologicals
- Proper citation
- Novus Cat#NB300-143, RRID:AB_10001196
- Product name
- Rabbit Polyclonal GAP-43 Antibody
- Antibody type
- Polyclonal
- Description
- Immunogen affinity purified.
- Reactivity
- Human, Mouse, Rat, Bovine, Canine, Chicken/Avian, Drosophila, Porcine, Simian
- Host
- Rabbit
- Isotype
- IgG
- Vial size
- 0.1 ml
- Concentration
- 1 mg/ml
- Storage
- Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.
Submitted references Differential Effects of Nasal Inflammation and Odor Deprivation on Layer-Specific Degeneration of the Mouse Olfactory Bulb.
Urokinase-type plasminogen activator (uPA) regulates the expression and function of growth-associated protein 43 (GAP-43) in the synapse.
Neuropathy and neural plasticity in the subcutaneous white adipose depot.
mTORC1 Signaling Is Palmitoylation-Dependent in Hippocampal Neurons and Non-neuronal Cells and Involves Dynamic Palmitoylation of LAMTOR1 and mTOR.
Callosal septa express guidance cues and are paramedian guideposts for human corpus callosum development.
The renin angiotensin system (RAS) mediates bifunctional growth regulation in melanoma and is a novel target for therapeutic intervention.
Parasympathectomy increases resting secretion of the submandibular gland in minipigs in the long term.
Early nerve fibre regeneration in individuals with type 1 diabetes after simultaneous pancreas and kidney transplantation.
The Mechanosensitive Ion Channel Piezo Inhibits Axon Regeneration.
Effects of Renal Denervation via Renal Artery Adventitial Cryoablation on Atrial Fibrillation and Cardiac Neural Remodeling.
Reduction of Proliferating Olfactory Cells and Low Expression of Extracellular Matrix Genes Are Hallmarks of the Aged Olfactory Mucosa.
Dose-Dependent Effects of Insulin-Like Growth Factor 1 in the Aged Olfactory Epithelium.
Cigarette Smoke-Induced Cell Death Causes Persistent Olfactory Dysfunction in Aged Mice.
Transcription factor activating protein 4 is synthetically lethal and a master regulator of MYCN-amplified neuroblastoma.
LncNEN885 inhibits epithelial-mesenchymal transition by partially regulation of Wnt/β-catenin signalling in gastroenteropancreatic neuroendocrine neoplasms.
Regulation of Neuroregeneration by Long Noncoding RNAs.
miR-3074-5p Promotes the Apoptosis but Inhibits the Invasiveness of Human Extravillous Trophoblast-Derived HTR8/SVneo Cells In Vitro.
Functional collagen conduits combined with human mesenchymal stem cells promote regeneration after sciatic nerve transection in dogs.
Cell-autonomous role of GFRα1 in the development of olfactory bulb GABAergic interneurons.
Redefining Perineural Invasion: Integration of Biology With Clinical Outcome.
An Essential Postdevelopmental Role for Lis1 in Mice.
Stroke promotes survival of nearby transplanted neural stem cells by decreasing their activation of caspase 3 while not affecting their differentiation.
A Population of Navigator Neurons Is Essential for Olfactory Map Formation during the Critical Period.
Axonal G3BP1 stress granule protein limits axonal mRNA translation and nerve regeneration.
Alterations in Corneal Sensory Nerves During Homeostasis, Aging, and After Injury in Mice Lacking the Heparan Sulfate Proteoglycan Syndecan-1.
Lack of TRPM5-Expressing Microvillous Cells in Mouse Main Olfactory Epithelium Leads to Impaired Odor-Evoked Responses and Olfactory-Guided Behavior in a Challenging Chemical Environment.
BDNF gene delivery mediated by neuron-targeted nanoparticles is neuroprotective in peripheral nerve injury.
Interaction of reactive astrocytes with type I collagen induces astrocytic scar formation through the integrin-N-cadherin pathway after spinal cord injury.
Axonal ribosomes and mRNAs associate with fragile X granules in adult rodent and human brains.
Deficiency of TREK-1 potassium channel exacerbates secondary injury following spinal cord injury in mice.
Macromolecular markers in normal human retina and applications to human retinal disease.
Discovery, Optimization, and Biological Evaluation of Sulfonamidoacetamides as an Inducer of Axon Regeneration.
Activating transcription factor 5 (ATF5) is essential for the maturation and survival of mouse basal vomeronasal sensory neurons.
Tau hyperphosphorylation in synaptosomes and neuroinflammation are associated with canine cognitive impairment.
APP Overexpression Causes Aβ-Independent Neuronal Death through Intrinsic Apoptosis Pathway.
Cigarette Smoke Delays Regeneration of the Olfactory Epithelium in Mice.
Human Dermal Fibroblasts Demonstrate Positive Immunostaining for Neuron- and Glia- Specific Proteins.
The relationship between changes in the expression of growth associated protein-43 and functional recovery of the injured inferior alveolar nerve following transection without repair in adult rats.
Neuromatous regeneration as a nerve response after catheter-based renal denervation therapy in a large animal model: immunohistochemical study.
Immunohistochemical and lectin histochemical studies on the developing olfactory organs of fetal camel.
Transient appearance of the epithelial invagination in the olfactory pit of chick embryos.
The vomeronasal organ of Lemur catta.
Shotgun proteomics reveals possible mechanisms for cognitive impairment in Mucopolysaccharidosis I mice.
Topographical transcriptome mapping of the mouse medial ganglionic eminence by spatially resolved RNA-seq.
Therapeutic potential of induced neural stem cells for spinal cord injury.
The morphological and molecular changes of brain cells exposed to direct current electric field stimulation.
A loss-of-function screen for phosphatases that regulate neurite outgrowth identifies PTPN12 as a negative regulator of TrkB tyrosine phosphorylation.
The vomeronasal complex of nocturnal strepsirhines and implications for the ancestral condition in primates.
Critical role of GFRα1 in the development and function of the main olfactory system.
IgSF8: a developmentally and functionally regulated cell adhesion molecule in olfactory sensory neuron axons and synapses.
Reproducible mouse sciatic nerve crush and subsequent assessment of regeneration by whole mount muscle analysis.
Creatine transporter immunolocalization in aged human and detached retinas.
Impaired sprouting and axonal atrophy in cerebellar climbing fibres following in vivo silencing of the growth-associated protein GAP-43.
Renal cystic disease proteins play critical roles in the organization of the olfactory epithelium.
In vivo olfactory model of APP-induced neurodegeneration reveals a reversible cell-autonomous function.
Sphingosine kinase 1/S1P pathway involvement in the GDNF-induced GAP43 transcription.
Fas-associated factor 1 as a regulator of olfactory axon guidance.
Composition of the migratory mass during development of the olfactory nerve.
Wnt/Frizzled family members mediate olfactory sensory neuron axon extension.
Interaction of amyloid precursor protein with contactins and NgCAM in the retinotectal system.
Chondroitinase applied to peripheral nerve repair averts retrograde axonal regeneration.
Tumorigenic properties of neurofibromin-deficient Schwann cells in culture and as syngrafts in Nf1 knockout mice.
Specific inhibition of CBP/beta-catenin interaction rescues defects in neuronal differentiation caused by a presenilin-1 mutation.
Loss of a FYN-regulated differentiation and growth arrest pathway in advanced stage neuroblastoma.
Loss of a FYN-regulated differentiation and growth arrest pathway in advanced stage neuroblastoma.
Regeneration of axons after nerve transection repair is enhanced by degradation of chondroitin sulfate proteoglycan.
Regeneration of axons after nerve transection repair is enhanced by degradation of chondroitin sulfate proteoglycan.
Metalloproteinase-dependent predegeneration in vitro enhances axonal regeneration within acellular peripheral nerve grafts.
Axonal regeneration into acellular nerve grafts is enhanced by degradation of chondroitin sulfate proteoglycan.
Hasegawa-Ishii S, Imamura F, Nagayama S, Murata M, Shimada A
eNeuro 2020 Mar Apr;7(2)
eNeuro 2020 Mar Apr;7(2)
Urokinase-type plasminogen activator (uPA) regulates the expression and function of growth-associated protein 43 (GAP-43) in the synapse.
Merino P, Diaz A, Torre ER, Yepes M
The Journal of biological chemistry 2020 Jan 10;295(2):619-630
The Journal of biological chemistry 2020 Jan 10;295(2):619-630
Neuropathy and neural plasticity in the subcutaneous white adipose depot.
Blaszkiewicz M, Willows JW, Dubois AL, Waible S, DiBello K, Lyons LL, Johnson CP, Paradie E, Banks N, Motyl K, Michael M, Harrison B, Townsend KL
PloS one 2019;14(9):e0221766
PloS one 2019;14(9):e0221766
mTORC1 Signaling Is Palmitoylation-Dependent in Hippocampal Neurons and Non-neuronal Cells and Involves Dynamic Palmitoylation of LAMTOR1 and mTOR.
Sanders SS, De Simone FI, Thomas GM
Frontiers in cellular neuroscience 2019;13:115
Frontiers in cellular neuroscience 2019;13:115
Callosal septa express guidance cues and are paramedian guideposts for human corpus callosum development.
Culjat M, Milošević NJ
Journal of anatomy 2019 Sep;235(3):670-686
Journal of anatomy 2019 Sep;235(3):670-686
The renin angiotensin system (RAS) mediates bifunctional growth regulation in melanoma and is a novel target for therapeutic intervention.
Renziehausen A, Wang H, Rao B, Weir L, Nigro CL, Lattanzio L, Merlano M, Vega-Rioja A, Del Carmen Fernandez-Carranco M, Hajji N, Matin R, Harwood C, Li S, Sim VR, O'Neill K, Evans A, Thompson A, Szlosarek P, Fleming C, Stebbing J, Proby C, Tzakos AG, Syed N, Crook T
Oncogene 2019 Mar;38(13):2320-2336
Oncogene 2019 Mar;38(13):2320-2336
Parasympathectomy increases resting secretion of the submandibular gland in minipigs in the long term.
Zhang XM, Huang Y, Cong X, Qu LH, Zhang K, Wu LL, Zhang Y, Yu GY
Journal of cellular physiology 2019 Jun;234(6):9515-9524
Journal of cellular physiology 2019 Jun;234(6):9515-9524
Early nerve fibre regeneration in individuals with type 1 diabetes after simultaneous pancreas and kidney transplantation.
Azmi S, Jeziorska M, Ferdousi M, Petropoulos IN, Ponirakis G, Marshall A, Alam U, Asghar O, Atkinson A, Jones W, Boulton AJM, Brines M, Augustine T, Malik RA
Diabetologia 2019 Aug;62(8):1478-1487
Diabetologia 2019 Aug;62(8):1478-1487
The Mechanosensitive Ion Channel Piezo Inhibits Axon Regeneration.
Song Y, Li D, Farrelly O, Miles L, Li F, Kim SE, Lo TY, Wang F, Li T, Thompson-Peer KL, Gong J, Murthy SE, Coste B, Yakubovich N, Patapoutian A, Xiang Y, Rompolas P, Jan LY, Jan YN
Neuron 2019 Apr 17;102(2):373-389.e6
Neuron 2019 Apr 17;102(2):373-389.e6
Effects of Renal Denervation via Renal Artery Adventitial Cryoablation on Atrial Fibrillation and Cardiac Neural Remodeling.
Wang W, Jiang Z, Lu R, Liu H, Ma N, Cai J, Tang M, Mei J
Cardiology research and practice 2018;2018:2603025
Cardiology research and practice 2018;2018:2603025
Reduction of Proliferating Olfactory Cells and Low Expression of Extracellular Matrix Genes Are Hallmarks of the Aged Olfactory Mucosa.
Ueha R, Shichino S, Ueha S, Kondo K, Kikuta S, Nishijima H, Matsushima K, Yamasoba T
Frontiers in aging neuroscience 2018;10:86
Frontiers in aging neuroscience 2018;10:86
Dose-Dependent Effects of Insulin-Like Growth Factor 1 in the Aged Olfactory Epithelium.
Ueha R, Kondo K, Ueha S, Yamasoba T
Frontiers in aging neuroscience 2018;10:385
Frontiers in aging neuroscience 2018;10:385
Cigarette Smoke-Induced Cell Death Causes Persistent Olfactory Dysfunction in Aged Mice.
Ueha R, Ueha S, Kondo K, Kikuta S, Yamasoba T
Frontiers in aging neuroscience 2018;10:183
Frontiers in aging neuroscience 2018;10:183
Transcription factor activating protein 4 is synthetically lethal and a master regulator of MYCN-amplified neuroblastoma.
Boboila S, Lopez G, Yu J, Banerjee D, Kadenhe-Chiweshe A, Connolly EP, Kandel JJ, Rajbhandari P, Silva JM, Califano A, Yamashiro DJ
Oncogene 2018 Oct;37(40):5451-5465
Oncogene 2018 Oct;37(40):5451-5465
LncNEN885 inhibits epithelial-mesenchymal transition by partially regulation of Wnt/β-catenin signalling in gastroenteropancreatic neuroendocrine neoplasms.
Wei YL, Hua J, Liu XY, Hua XM, Sun C, Bai JA, Tang QY
Cancer science 2018 Oct;109(10):3139-3148
Cancer science 2018 Oct;109(10):3139-3148
Regulation of Neuroregeneration by Long Noncoding RNAs.
Perry RB, Hezroni H, Goldrich MJ, Ulitsky I
Molecular cell 2018 Nov 1;72(3):553-567.e5
Molecular cell 2018 Nov 1;72(3):553-567.e5
miR-3074-5p Promotes the Apoptosis but Inhibits the Invasiveness of Human Extravillous Trophoblast-Derived HTR8/SVneo Cells In Vitro.
Gu Y, Shi Y, Yang Q, Gu WW, He YP, Zheng HJ, Zhang X, Wang JM, Wang J
Reproductive sciences (Thousand Oaks, Calif.) 2018 May;25(5):690-699
Reproductive sciences (Thousand Oaks, Calif.) 2018 May;25(5):690-699
Functional collagen conduits combined with human mesenchymal stem cells promote regeneration after sciatic nerve transection in dogs.
Cui Y, Yao Y, Zhao Y, Xiao Z, Cao Z, Han S, Li X, Huan Y, Pan J, Dai J
Journal of tissue engineering and regenerative medicine 2018 May;12(5):1285-1296
Journal of tissue engineering and regenerative medicine 2018 May;12(5):1285-1296
Cell-autonomous role of GFRα1 in the development of olfactory bulb GABAergic interneurons.
Zechel S, Fernandez-Suarez D, Ibáñez CF
Biology open 2018 May 18;7(5)
Biology open 2018 May 18;7(5)
Redefining Perineural Invasion: Integration of Biology With Clinical Outcome.
Schmitd LB, Beesley LJ, Russo N, Bellile EL, Inglehart RC, Liu M, Romanowicz G, Wolf GT, Taylor JMG, D'Silva NJ
Neoplasia (New York, N.Y.) 2018 Jul;20(7):657-667
Neoplasia (New York, N.Y.) 2018 Jul;20(7):657-667
An Essential Postdevelopmental Role for Lis1 in Mice.
Hines TJ, Gao X, Sahu S, Lange MM, Turner JR, Twiss JL, Smith DS
eNeuro 2018 Jan-Feb;5(1)
eNeuro 2018 Jan-Feb;5(1)
Stroke promotes survival of nearby transplanted neural stem cells by decreasing their activation of caspase 3 while not affecting their differentiation.
Kosi N, Alić I, Salamon I, Mitrečić D
Neuroscience letters 2018 Feb 14;666:111-119
Neuroscience letters 2018 Feb 14;666:111-119
A Population of Navigator Neurons Is Essential for Olfactory Map Formation during the Critical Period.
Wu Y, Ma L, Duyck K, Long CC, Moran A, Scheerer H, Blanck J, Peak A, Box A, Perera A, Yu CR
Neuron 2018 Dec 5;100(5):1066-1082.e6
Neuron 2018 Dec 5;100(5):1066-1082.e6
Axonal G3BP1 stress granule protein limits axonal mRNA translation and nerve regeneration.
Sahoo PK, Lee SJ, Jaiswal PB, Alber S, Kar AN, Miller-Randolph S, Taylor EE, Smith T, Singh B, Ho TS, Urisman A, Chand S, Pena EA, Burlingame AL, Woolf CJ, Fainzilber M, English AW, Twiss JL
Nature communications 2018 Aug 22;9(1):3358
Nature communications 2018 Aug 22;9(1):3358
Alterations in Corneal Sensory Nerves During Homeostasis, Aging, and After Injury in Mice Lacking the Heparan Sulfate Proteoglycan Syndecan-1.
Pal-Ghosh S, Tadvalkar G, Stepp MA
Investigative ophthalmology & visual science 2017 Oct 1;58(12):4959-4975
Investigative ophthalmology & visual science 2017 Oct 1;58(12):4959-4975
Lack of TRPM5-Expressing Microvillous Cells in Mouse Main Olfactory Epithelium Leads to Impaired Odor-Evoked Responses and Olfactory-Guided Behavior in a Challenging Chemical Environment.
Lemons K, Fu Z, Aoudé I, Ogura T, Sun J, Chang J, Mbonu K, Matsumoto I, Arakawa H, Lin W
eNeuro 2017 May-Jun;4(3)
eNeuro 2017 May-Jun;4(3)
BDNF gene delivery mediated by neuron-targeted nanoparticles is neuroprotective in peripheral nerve injury.
Lopes CDF, Gonçalves NP, Gomes CP, Saraiva MJ, Pêgo AP
Biomaterials 2017 Mar;121:83-96
Biomaterials 2017 Mar;121:83-96
Interaction of reactive astrocytes with type I collagen induces astrocytic scar formation through the integrin-N-cadherin pathway after spinal cord injury.
Hara M, Kobayakawa K, Ohkawa Y, Kumamaru H, Yokota K, Saito T, Kijima K, Yoshizaki S, Harimaya K, Nakashima Y, Okada S
Nature medicine 2017 Jul;23(7):818-828
Nature medicine 2017 Jul;23(7):818-828
Axonal ribosomes and mRNAs associate with fragile X granules in adult rodent and human brains.
Akins MR, Berk-Rauch HE, Kwan KY, Mitchell ME, Shepard KA, Korsak LI, Stackpole EE, Warner-Schmidt JL, Sestan N, Cameron HA, Fallon JR
Human molecular genetics 2017 Jan 1;26(1):192-209
Human molecular genetics 2017 Jan 1;26(1):192-209
Deficiency of TREK-1 potassium channel exacerbates secondary injury following spinal cord injury in mice.
Fang Y, Huang X, Wan Y, Tian H, Tian Y, Wang W, Zhu S, Xie M
Journal of neurochemistry 2017 Apr;141(2):236-246
Journal of neurochemistry 2017 Apr;141(2):236-246
Macromolecular markers in normal human retina and applications to human retinal disease.
de Souza CF, Nivison-Smith L, Christie DL, Polkinghorne P, McGhee C, Kalloniatis M, Acosta ML
Experimental eye research 2016 Sep;150:135-48
Experimental eye research 2016 Sep;150:135-48
Discovery, Optimization, and Biological Evaluation of Sulfonamidoacetamides as an Inducer of Axon Regeneration.
Ku JM, Park K, Lee JH, Cho KJ, Nam YJ, Jeong DY, Kim YH, Kwon S, Park JY, Yang J, Nam TG, Yoon SH, Ahn S, Choi Y
Journal of medicinal chemistry 2016 May 26;59(10):4676-87
Journal of medicinal chemistry 2016 May 26;59(10):4676-87
Activating transcription factor 5 (ATF5) is essential for the maturation and survival of mouse basal vomeronasal sensory neurons.
Nakano H, Iida Y, Suzuki M, Aoki M, Umemura M, Takahashi S, Takahashi Y
Cell and tissue research 2016 Mar;363(3):621-33
Cell and tissue research 2016 Mar;363(3):621-33
Tau hyperphosphorylation in synaptosomes and neuroinflammation are associated with canine cognitive impairment.
Smolek T, Madari A, Farbakova J, Kandrac O, Jadhav S, Cente M, Brezovakova V, Novak M, Zilka N
The Journal of comparative neurology 2016 Mar 1;524(4):874-95
The Journal of comparative neurology 2016 Mar 1;524(4):874-95
APP Overexpression Causes Aβ-Independent Neuronal Death through Intrinsic Apoptosis Pathway.
Cheng N, Jiao S, Gumaste A, Bai L, Belluscio L
eNeuro 2016 Jul-Aug;3(4)
eNeuro 2016 Jul-Aug;3(4)
Cigarette Smoke Delays Regeneration of the Olfactory Epithelium in Mice.
Ueha R, Ueha S, Sakamoto T, Kanaya K, Suzukawa K, Nishijima H, Kikuta S, Kondo K, Matsushima K, Yamasoba T
Neurotoxicity research 2016 Aug;30(2):213-24
Neurotoxicity research 2016 Aug;30(2):213-24
Human Dermal Fibroblasts Demonstrate Positive Immunostaining for Neuron- and Glia- Specific Proteins.
Janmaat CJ, de Rooij KE, Locher H, de Groot SC, de Groot JC, Frijns JH, Huisman MA
PloS one 2015;10(12):e0145235
PloS one 2015;10(12):e0145235
The relationship between changes in the expression of growth associated protein-43 and functional recovery of the injured inferior alveolar nerve following transection without repair in adult rats.
Ceber M, Sener U, Mihmanli A, Kilic U, Topcu B, Karakas M
Journal of cranio-maxillo-facial surgery : official publication of the European Association for Cranio-Maxillo-Facial Surgery 2015 Nov;43(9):1906-13
Journal of cranio-maxillo-facial surgery : official publication of the European Association for Cranio-Maxillo-Facial Surgery 2015 Nov;43(9):1906-13
Neuromatous regeneration as a nerve response after catheter-based renal denervation therapy in a large animal model: immunohistochemical study.
Rousselle SD, Brants IK, Sakaoka A, Hubbard B, Jackson ND, Wicks JR, Dillon KN, Naiche LA, Hart R, Garza JA, Tellez A
Circulation. Cardiovascular interventions 2015 May;8(5)
Circulation. Cardiovascular interventions 2015 May;8(5)
Immunohistochemical and lectin histochemical studies on the developing olfactory organs of fetal camel.
Ibrahim D, Taniguchi K, Yamamoto Y, Taniguchi K, Nakamuta N
Microscopy research and technique 2015 Jul;78(7):613-9
Microscopy research and technique 2015 Jul;78(7):613-9
Transient appearance of the epithelial invagination in the olfactory pit of chick embryos.
Nakamuta S, Nakamuta N, Yamamoto Y, Onodera N, Araki I
The Journal of veterinary medical science 2015 Jan;77(1):89-93
The Journal of veterinary medical science 2015 Jan;77(1):89-93
The vomeronasal organ of Lemur catta.
Smith TD, Muchlinski MN, Bhatnagar KP, Durham EL, Bonar CJ, Burrows AM
American journal of primatology 2015 Feb;77(2):229-38
American journal of primatology 2015 Feb;77(2):229-38
Shotgun proteomics reveals possible mechanisms for cognitive impairment in Mucopolysaccharidosis I mice.
Baldo G, Lorenzini DM, Santos DS, Mayer FQ, Vitry S, Bigou S, Heard JM, Matte U, Giugliani R
Molecular genetics and metabolism 2015 Feb;114(2):138-45
Molecular genetics and metabolism 2015 Feb;114(2):138-45
Topographical transcriptome mapping of the mouse medial ganglionic eminence by spatially resolved RNA-seq.
Zechel S, Zajac P, Lönnerberg P, Ibáñez CF, Linnarsson S
Genome biology 2014;15(10):486
Genome biology 2014;15(10):486
Therapeutic potential of induced neural stem cells for spinal cord injury.
Hong JY, Lee SH, Lee SC, Kim JW, Kim KP, Kim SM, Tapia N, Lim KT, Kim J, Ahn HS, Ko K, Shin CY, Lee HT, Schöler HR, Hyun JK, Han DW
The Journal of biological chemistry 2014 Nov 21;289(47):32512-25
The Journal of biological chemistry 2014 Nov 21;289(47):32512-25
The morphological and molecular changes of brain cells exposed to direct current electric field stimulation.
Pelletier SJ, Lagacé M, St-Amour I, Arsenault D, Cisbani G, Chabrat A, Fecteau S, Lévesque M, Cicchetti F
The international journal of neuropsychopharmacology 2014 Dec 7;18(5)
The international journal of neuropsychopharmacology 2014 Dec 7;18(5)
A loss-of-function screen for phosphatases that regulate neurite outgrowth identifies PTPN12 as a negative regulator of TrkB tyrosine phosphorylation.
Ambjørn M, Dubreuil V, Miozzo F, Nigon F, Møller B, Issazadeh-Navikas S, Berg J, Lees M, Sap J
PloS one 2013;8(6):e65371
PloS one 2013;8(6):e65371
The vomeronasal complex of nocturnal strepsirhines and implications for the ancestral condition in primates.
Garrett EC, Dennis JC, Bhatnagar KP, Durham EL, Burrows AM, Bonar CJ, Steckler NK, Morrison EE, Smith TD
Anatomical record (Hoboken, N.J. : 2007) 2013 Dec;296(12):1881-94
Anatomical record (Hoboken, N.J. : 2007) 2013 Dec;296(12):1881-94
Critical role of GFRα1 in the development and function of the main olfactory system.
Marks C, Belluscio L, Ibáñez CF
The Journal of neuroscience : the official journal of the Society for Neuroscience 2012 Nov 28;32(48):17306-20
The Journal of neuroscience : the official journal of the Society for Neuroscience 2012 Nov 28;32(48):17306-20
IgSF8: a developmentally and functionally regulated cell adhesion molecule in olfactory sensory neuron axons and synapses.
Ray A, Treloar HB
Molecular and cellular neurosciences 2012 Jul;50(3-4):238-49
Molecular and cellular neurosciences 2012 Jul;50(3-4):238-49
Reproducible mouse sciatic nerve crush and subsequent assessment of regeneration by whole mount muscle analysis.
Bauder AR, Ferguson TA
Journal of visualized experiments : JoVE 2012 Feb 22;(60)
Journal of visualized experiments : JoVE 2012 Feb 22;(60)
Creatine transporter immunolocalization in aged human and detached retinas.
de Souza CF, Kalloniatis M, Christie DL, Polkinghorne PJ, McGhee CN, Acosta ML
Investigative ophthalmology & visual science 2012 Apr 18;53(4):1936-45
Investigative ophthalmology & visual science 2012 Apr 18;53(4):1936-45
Impaired sprouting and axonal atrophy in cerebellar climbing fibres following in vivo silencing of the growth-associated protein GAP-43.
Grasselli G, Mandolesi G, Strata P, Cesare P
PloS one 2011;6(6):e20791
PloS one 2011;6(6):e20791
Renal cystic disease proteins play critical roles in the organization of the olfactory epithelium.
Pluznick JL, Rodriguez-Gil DJ, Hull M, Mistry K, Gattone V, Johnson CA, Weatherbee S, Greer CA, Caplan MJ
PloS one 2011;6(5):e19694
PloS one 2011;6(5):e19694
In vivo olfactory model of APP-induced neurodegeneration reveals a reversible cell-autonomous function.
Cheng N, Cai H, Belluscio L
The Journal of neuroscience : the official journal of the Society for Neuroscience 2011 Sep 28;31(39):13699-704
The Journal of neuroscience : the official journal of the Society for Neuroscience 2011 Sep 28;31(39):13699-704
Sphingosine kinase 1/S1P pathway involvement in the GDNF-induced GAP43 transcription.
Murakami M, Ito H, Hagiwara K, Kobayashi M, Hoshikawa A, Takagi A, Kojima T, Tamiya-Koizumi K, Sobue S, Ichihara M, Suzuki M, Banno Y, Nozawa Y, Murate T
Journal of cellular biochemistry 2011 Nov;112(11):3449-58
Journal of cellular biochemistry 2011 Nov;112(11):3449-58
Fas-associated factor 1 as a regulator of olfactory axon guidance.
Cheng K, Bai L, Belluscio L
The Journal of neuroscience : the official journal of the Society for Neuroscience 2011 Aug 17;31(33):11905-13
The Journal of neuroscience : the official journal of the Society for Neuroscience 2011 Aug 17;31(33):11905-13
Composition of the migratory mass during development of the olfactory nerve.
Miller AM, Treloar HB, Greer CA
The Journal of comparative neurology 2010 Dec 15;518(24):4825-41
The Journal of comparative neurology 2010 Dec 15;518(24):4825-41
Wnt/Frizzled family members mediate olfactory sensory neuron axon extension.
Rodriguez-Gil DJ, Greer CA
The Journal of comparative neurology 2008 Nov 20;511(3):301-17
The Journal of comparative neurology 2008 Nov 20;511(3):301-17
Interaction of amyloid precursor protein with contactins and NgCAM in the retinotectal system.
Osterfield M, Egelund R, Young LM, Flanagan JG
Development (Cambridge, England) 2008 Mar;135(6):1189-99
Development (Cambridge, England) 2008 Mar;135(6):1189-99
Chondroitinase applied to peripheral nerve repair averts retrograde axonal regeneration.
Graham JB, Neubauer D, Xue QS, Muir D
Experimental neurology 2007 Jan;203(1):185-95
Experimental neurology 2007 Jan;203(1):185-95
Tumorigenic properties of neurofibromin-deficient Schwann cells in culture and as syngrafts in Nf1 knockout mice.
Wu M, Wallace MR, Muir D
Journal of neuroscience research 2005 Nov 1;82(3):357-67
Journal of neuroscience research 2005 Nov 1;82(3):357-67
Specific inhibition of CBP/beta-catenin interaction rescues defects in neuronal differentiation caused by a presenilin-1 mutation.
Teo JL, Ma H, Nguyen C, Lam C, Kahn M
Proceedings of the National Academy of Sciences of the United States of America 2005 Aug 23;102(34):12171-6
Proceedings of the National Academy of Sciences of the United States of America 2005 Aug 23;102(34):12171-6
Loss of a FYN-regulated differentiation and growth arrest pathway in advanced stage neuroblastoma.
Berwanger B, Hartmann O, Bergmann E, Bernard S, Nielsen D, Krause M, Kartal A, Flynn D, Wiedemeyer R, Schwab M, Schäfer H, Christiansen H, Eilers M
Cancer cell 2002 Nov;2(5):377-86
Cancer cell 2002 Nov;2(5):377-86
Loss of a FYN-regulated differentiation and growth arrest pathway in advanced stage neuroblastoma.
Berwanger B, Hartmann O, Bergmann E, Bernard S, Nielsen D, Krause M, Kartal A, Flynn D, Wiedemeyer R, Schwab M, Schäfer H, Christiansen H, Eilers M
Cancer cell 2002 Nov;2(5):377-86
Cancer cell 2002 Nov;2(5):377-86
Regeneration of axons after nerve transection repair is enhanced by degradation of chondroitin sulfate proteoglycan.
Zuo J, Neubauer D, Graham J, Krekoski CA, Ferguson TA, Muir D
Experimental neurology 2002 Jul;176(1):221-8
Experimental neurology 2002 Jul;176(1):221-8
Regeneration of axons after nerve transection repair is enhanced by degradation of chondroitin sulfate proteoglycan.
Zuo J, Neubauer D, Graham J, Krekoski CA, Ferguson TA, Muir D
Experimental neurology 2002 Jul;176(1):221-8
Experimental neurology 2002 Jul;176(1):221-8
Metalloproteinase-dependent predegeneration in vitro enhances axonal regeneration within acellular peripheral nerve grafts.
Krekoski CA, Neubauer D, Graham JB, Muir D
The Journal of neuroscience : the official journal of the Society for Neuroscience 2002 Dec 1;22(23):10408-15
The Journal of neuroscience : the official journal of the Society for Neuroscience 2002 Dec 1;22(23):10408-15
Axonal regeneration into acellular nerve grafts is enhanced by degradation of chondroitin sulfate proteoglycan.
Krekoski CA, Neubauer D, Zuo J, Muir D
The Journal of neuroscience : the official journal of the Society for Neuroscience 2001 Aug 15;21(16):6206-13
The Journal of neuroscience : the official journal of the Society for Neuroscience 2001 Aug 15;21(16):6206-13
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Supportive validation
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- Western Blot: GAP-43 Antibody [NB300-143] - Western blots of homogenate of cow cerebellum stained with RPCA-GAP-43 . A prominent band running at ~43kDa represents the full length GAP-43.
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- Western Blot: GAP-43 Antibody [NB300-143] - Different tissue and cell lysates using rabbit pAb to GAP43, dilution 1:20,000 in green: [1] protein standard (red), [2] rat brain, [3] rat spinal cord, [4] mouse brain, [5] mouse spinal cord, [6] SH-SY5Y cells, [7] C6 cells. Single band at 43 kDa mark corresponds to GAP43 protein. The GAP43 protein is detected only in the lysates of neuronal origin. C6 cells are a rat glioma cell line and do not express GAP43 protein
Supportive validation
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- Novus Biologicals (provider)
- Main image
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- Immunohistochemistry-Paraffin: GAP-43 Antibody [NB300-143] - Review image from confirmed customer on mouse E15.5 paraffin sections.
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- Novus Biologicals (provider)
- Main image
- Experimental details
- Immunohistochemistry-Paraffin: GAP-43 Antibody [NB300-143] - Posterior MOE sections at approximately the same region where EOG was recorded were obtained from control and Skn-1a-/- mice exposed to either water or chemicals for 2 wks. The sections were immunoreacted with antibodies against GAP43 and OMP and stained with DAPI. Confocal images were taken from olfactory turbinate II. Similar morphology and marker expression were found in four groups of mice, indicating there was no obvious tissue damage in both control and Skn-1a-/- mice after chemical exposure in the posterior MOE regions where EOG recordings were performed. Scale bar: 50 um. Image collected and cropped by CiteAb from the following publication (http://eneuro.sfn.org/lookup/doi/10.1523/ENEURO.0135-17.2017), licensed under a CC-BY licence.
