BS8336

antibody from Bioworld Technology, Inc
Targeting: MYLK3 caMLCK, MLCK
Provider product page for BS8336
Western blot
Immunocytochemistry
Immunohistochemistry

Antibody data

Product number
BS8336 - Provider product page
Provider
Bioworld Technology, Inc
Product name
MYLK3 polyclonal antibody
Antibody type
Polyclonal
Antigen
Recombinant full length Human MYLK3.
Description
The Ca2+/calmodulin-dependent protein kinases (CaM kinases) are a structurally related subfamily of serine/threonine kinases that includes CaMKI, CaMKII, CaMKIV and Myosin light chain kinases (MYLKs, also designated MLCKs). The MYLK kinases phosphorylate Myosin regulatory light chains to catalyze Myosin interaction with Actin filaments, resulting in contractile activity. MYLK3 (Myosin light chain kinase 3) is a 795 amino acid cardiac-specific protein that contains one protein kinase domain and belongs to the protein kinase superfamily. Like other MYLK kinases, MYLK3 is thought to play a role in smooth muscle contraction, specifically using magnesium as a cofactor to catalyze the ATP-dependent phosphorylation of Myosin light chain proteins. Additionally, MYLK3 may regulate sarcomere assembly in heart tissue, possibly mediating proper heart function.
Reactivity
Human
Host
Rabbit
Isotype
IgG
Vial size
100ul
Concentration
1 mg/ml
Storage
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
MYLK3 protein structure - BS8336 shown in red.