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- References [6]
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- Validations
- Western blot [1]
- Immunocytochemistry [1]
- Flow cytometry [1]
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- Product number
- 15557-1-AP - Provider product page
- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#15557-1-AP, RRID:AB_2261563
- Product name
- DIRAS2 antibody
- Antibody type
- Polyclonal
- Description
- DIRAS2 antibody (Cat. #15557-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse, rat and has been validated for the following applications: FC, IF, IP, WB,ELISA.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references eNAMPT/Ac-STAT3/DIRAS2 Axis Promotes Development and Cancer Stemness in Triple-Negative Breast Cancer by Enhancing Cytokine Crosstalk Between Tumor-Associated Macrophages and Cancer Cells.
Structural Domain Analysis of Heparin and Heparan Sulfate Combined With Label-Free Quantitative Proteomics to Elucidate Their Functional Diversity in Liver Cancer and APAP-Induced Liver Injury.
The UBE2F-CRL5(ASB11)-DIRAS2 axis is an oncogene and tumor suppressor cascade in pancreatic cancer cells.
Frequent Epigenetic Inactivation of DIRAS-1 and DIRAS-2 Contributes to Chemo-Resistance in Gliomas.
Di-Ras2 promotes renal cell carcinoma formation by activating the mitogen-activated protein kinase pathway in the absence of von Hippel-Lindau protein.
Expression of the ADHD candidate gene Diras2 in the brain.
Zhang L, Wang L, Xu Z, Zhang X, Guan S, Liu Z, Gu S, Zhao L, Bai W, Li T, Zhao X
International journal of biological sciences 2025;21(5):2027-2047
International journal of biological sciences 2025;21(5):2027-2047
Structural Domain Analysis of Heparin and Heparan Sulfate Combined With Label-Free Quantitative Proteomics to Elucidate Their Functional Diversity in Liver Cancer and APAP-Induced Liver Injury.
An Z, Chen Q, Bu C, Chen L, Shi D, Zhang B, Jin L, Chi L
Molecular & cellular proteomics : MCP 2025 Nov;24(11):101090
Molecular & cellular proteomics : MCP 2025 Nov;24(11):101090
The UBE2F-CRL5(ASB11)-DIRAS2 axis is an oncogene and tumor suppressor cascade in pancreatic cancer cells.
Chang Y, Chen Q, Li H, Xu J, Tan M, Xiong X, Sun Y
Developmental cell 2024 May 20;59(10):1317-1332.e5
Developmental cell 2024 May 20;59(10):1317-1332.e5
Frequent Epigenetic Inactivation of DIRAS-1 and DIRAS-2 Contributes to Chemo-Resistance in Gliomas.
Rothhammer-Hampl T, Liesenberg F, Hansen N, Hoja S, Delic S, Reifenberger G, Riemenschneider MJ
Cancers 2021 Oct 12;13(20)
Cancers 2021 Oct 12;13(20)
Di-Ras2 promotes renal cell carcinoma formation by activating the mitogen-activated protein kinase pathway in the absence of von Hippel-Lindau protein.
Rao H, Li X, Liu M, Liu J, Li X, Xu J, Li L, Gao WQ
Oncogene 2020 May;39(19):3853-3866
Oncogene 2020 May;39(19):3853-3866
Expression of the ADHD candidate gene Diras2 in the brain.
Grünewald L, Becker N, Camphausen A, O'Leary A, Lesch KP, Freudenberg F, Reif A
Journal of neural transmission (Vienna, Austria : 1996) 2018 Jun;125(6):913-923
Journal of neural transmission (Vienna, Austria : 1996) 2018 Jun;125(6):913-923
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Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- human brain tissue were subjected to SDS PAGE followed by western blot with 15557-1-AP(DIRAS2 antibody) at dilution of 1:500
- Sample type
- tissue
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- Immunofluorescent analysis of Hela cells, using DIRAS2 antibody 15557-1-AP at 1:25 dilution and Rhodamine-labeled goat anti-rabbit IgG (red).
- Sample type
- cell line
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- The DIRAS2 antibody from Proteintech is a rabbit polyclonal antibody to a recombinant protein of human DIRAS2. This antibody recognizes human,mouse,rat antigen. The DIRAS2 antibody has been validated for the following applications: ELISA, WB, IF, FC analysis.
