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Western blot
ImmunocytochemistryAntibody data
- Antibody Data
- Antigen structure
- References [11]
- Comments [0]
- Validations
- Western blot [1]
- Immunohistochemistry [1]
- Other assay [1]
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- Product number
- NB110-60017 - Provider product page
- Provider
- Novus Biologicals
- Proper citation
- Novus Cat#NB110-60017, RRID:AB_2277517
- Product name
- Mouse Monoclonal Dopamine D1R/DRD1 Antibody
- Antibody type
- Monoclonal
- Description
- Protein A purified. This antibody is specific for Dopamine Receptor D1A. There is no cross-reactivity with D1B (D5) receptor.
- Reactivity
- Human, Mouse, Rat, Bovine, Canine, Porcine, Rabbit, Sheep
- Host
- Mouse
- Isotype
- IgG
- Vial size
- 0.1 ml
- Concentration
- 1.0 mg/ml
- Storage
- Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.
Submitted references Nucleus accumbens medium spiny neurons subtypes signal both reward and aversion.
Role of laterodorsal tegmentum projections to nucleus accumbens in reward-related behaviors.
Microglial dopamine receptor elimination defines sex-specific nucleus accumbens development and social behavior in adolescent rats.
Nucleus Accumbens Microcircuit Underlying D2-MSN-Driven Increase in Motivation.
Dopamine-Induced Changes in Gαolf Protein Levels in Striatonigral and Striatopallidal Medium Spiny Neurons Underlie the Genesis of l-DOPA-Induced Dyskinesia in Parkinsonian Mice.
Dopamine enhances duodenal epithelial permeability via the dopamine D5 receptor in rodent.
Activation of D2 dopamine receptor-expressing neurons in the nucleus accumbens increases motivation.
Fixation strategies for retinal immunohistochemistry.
Inhibition of adult rat retinal ganglion cells by D1-type dopamine receptor activation.
Immunoblot and immunohistochemical comparison of murine monoclonal antibodies specific for the rat D1a and D1b dopamine receptor subtypes.
Immunoblot and immunohistochemical comparison of murine monoclonal antibodies specific for the rat D1a and D1b dopamine receptor subtypes.
Soares-Cunha C, de Vasconcelos NAP, Coimbra B, Domingues AV, Silva JM, Loureiro-Campos E, Gaspar R, Sotiropoulos I, Sousa N, Rodrigues AJ
Molecular psychiatry 2020 Dec;25(12):3241-3255
Molecular psychiatry 2020 Dec;25(12):3241-3255
Role of laterodorsal tegmentum projections to nucleus accumbens in reward-related behaviors.
Coimbra B, Soares-Cunha C, Vasconcelos NAP, Domingues AV, Borges S, Sousa N, Rodrigues AJ
Nature communications 2019 Sep 12;10(1):4138
Nature communications 2019 Sep 12;10(1):4138
Microglial dopamine receptor elimination defines sex-specific nucleus accumbens development and social behavior in adolescent rats.
Kopec AM, Smith CJ, Ayre NR, Sweat SC, Bilbo SD
Nature communications 2018 Sep 25;9(1):3769
Nature communications 2018 Sep 25;9(1):3769
Nucleus Accumbens Microcircuit Underlying D2-MSN-Driven Increase in Motivation.
Soares-Cunha C, Coimbra B, Domingues AV, Vasconcelos N, Sousa N, Rodrigues AJ
eNeuro 2018 Mar-Apr;5(2)
eNeuro 2018 Mar-Apr;5(2)
Dopamine-Induced Changes in Gαolf Protein Levels in Striatonigral and Striatopallidal Medium Spiny Neurons Underlie the Genesis of l-DOPA-Induced Dyskinesia in Parkinsonian Mice.
Morigaki R, Okita S, Goto S
Frontiers in cellular neuroscience 2017;11:26
Frontiers in cellular neuroscience 2017;11:26
Dopamine enhances duodenal epithelial permeability via the dopamine D5 receptor in rodent.
Feng XY, Zhang DN, Wang YA, Fan RF, Hong F, Zhang Y, Li Y, Zhu JX
Acta physiologica (Oxford, England) 2017 May;220(1):113-123
Acta physiologica (Oxford, England) 2017 May;220(1):113-123
Activation of D2 dopamine receptor-expressing neurons in the nucleus accumbens increases motivation.
Soares-Cunha C, Coimbra B, David-Pereira A, Borges S, Pinto L, Costa P, Sousa N, Rodrigues AJ
Nature communications 2016 Jun 23;7:11829
Nature communications 2016 Jun 23;7:11829
Fixation strategies for retinal immunohistochemistry.
Stradleigh TW, Ishida AT
Progress in retinal and eye research 2015 Sep;48:181-202
Progress in retinal and eye research 2015 Sep;48:181-202
Inhibition of adult rat retinal ganglion cells by D1-type dopamine receptor activation.
Hayashida Y, Rodríguez CV, Ogata G, Partida GJ, Oi H, Stradleigh TW, Lee SC, Colado AF, Ishida AT
The Journal of neuroscience : the official journal of the Society for Neuroscience 2009 Nov 25;29(47):15001-16
The Journal of neuroscience : the official journal of the Society for Neuroscience 2009 Nov 25;29(47):15001-16
Immunoblot and immunohistochemical comparison of murine monoclonal antibodies specific for the rat D1a and D1b dopamine receptor subtypes.
Luedtke RR, Griffin SA, Conroy SS, Jin X, Pinto A, Sesack SR
Journal of neuroimmunology 1999 Nov 15;101(2):170-87
Journal of neuroimmunology 1999 Nov 15;101(2):170-87
Immunoblot and immunohistochemical comparison of murine monoclonal antibodies specific for the rat D1a and D1b dopamine receptor subtypes.
Luedtke RR, Griffin SA, Conroy SS, Jin X, Pinto A, Sesack SR
Journal of neuroimmunology 1999 Nov 15;101(2):170-87
Journal of neuroimmunology 1999 Nov 15;101(2):170-87
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Supportive validation
- Submitted by
- Novus Biologicals (provider)
- Main image
- Experimental details
- Western Blot: Dopamine D1 R/DRD1 Antibody (SG2-D1a) [NB110-60017] - Analysis of lysates from Sf9 cells which were transfected with rat DR-D1b (Lane 1) or DR-D1a (Lane 2) using DRD1 antibody (clone SG2-D1a). This clone detected D1a receptor only and was not cross-reactive against DR-D1b (Note: these results are similiar to those shown in J. Neuroimmunol. 101:170-187 publication.)
Supportive validation
- Submitted by
- Novus Biologicals (provider)
- Main image
- Experimental details
- Immunohistochemistry: Dopamine D1R/DRD1 Antibody (SG2-D1a) [NB110-60017] - Dopamine D1 R/DRD1 Antibody (SG2-D1a) [NB110-60017] - Analysis of Dopamine Receptor D1 in rat retinal whole mounts and sections. Image from verified customer review.
Supportive validation
- Submitted by
- Novus Biologicals (provider)
- Main image
- Experimental details
- Immunohistochemistry Free-Floating: Dopamine D1 R/DRD1 Antibody (SG2-D1a) [NB110-60017] - Analysis of Dopamine D1 R in free floating rat brain slices using Dopamine D1 R antibody. Image from verified customer review.
