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- Antibody Data
- Antigen structure
- References [11]
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- Validations
- Western blot [1]
- Immunocytochemistry [1]
- Immunohistochemistry [2]
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- Product number
- 15104-1-AP - Provider product page
- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#15104-1-AP, RRID:AB_2207757
- Product name
- TNIP1 antibody
- Antibody type
- Polyclonal
- Description
- KD/KO validated TNIP1 antibody (Cat. #15104-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse and has been validated for the following applications: IF, IHC, IP, WB,ELISA.
- Reactivity
- Human, Mouse
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references ABIN1 (Q478) is Required to Prevent Hematopoietic Deficiencies through Regulating Type I IFNs Expression.
TNIP1 inhibits selective autophagy via bipartite interaction with LC3/GABARAP and TAX1BP1.
A20 binding and inhibitor of nuclear factor kappa B (NF-κB)-1 (ABIN-1): a novel modulator of mitochondrial autophagy.
Ubiquitin-binding domain in ABIN1 is critical for regulating cell death and inflammation during development.
ABIN-1 is a key regulator in RIPK1-dependent apoptosis (RDA) and necroptosis, and ABIN-1 deficiency potentiates necroptosis-based cancer therapy in colorectal cancer.
S100A6 promotes proliferation and migration of HepG2 cells via increased ubiquitin-dependent degradation of p53.
ABIN-1 protects chondrocytes from lipopolysaccharide-induced inflammatory injury through the inactivation of NF-κB signalling.
A20 and ABIN1 Suppression of a Keratinocyte Inflammatory Program with a Shared Single-Cell Expression Signature in Diverse Human Rashes.
ABIN1 inhibits HDAC1 ubiquitination and protects it from both proteasome- and lysozyme-dependent degradation.
Immune regulator ABIN1 suppresses HIV-1 transcription by negatively regulating the ubiquitination of Tat.
A functional genomics screen for microRNA regulators of NF-kappaB signaling.
Wu X, Wang Y, Chen B, Liu Y, Li F, Ou Y, Zhang H, Wu X, Li X, Wang L, Rong W, Liu J, Xing M, Zhao X, Liu H, Ge L, Lv A, Wang L, Wang Z, Li M, Zhang H
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2024 Jan;11(3):e2303555
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2024 Jan;11(3):e2303555
TNIP1 inhibits selective autophagy via bipartite interaction with LC3/GABARAP and TAX1BP1.
Le Guerroué F, Bunker EN, Rosencrans WM, Nguyen JT, Basar MA, Werner A, Chou TF, Wang C, Youle RJ
Molecular cell 2023 Mar 16;83(6):927-941.e8
Molecular cell 2023 Mar 16;83(6):927-941.e8
A20 binding and inhibitor of nuclear factor kappa B (NF-κB)-1 (ABIN-1): a novel modulator of mitochondrial autophagy.
Merline R, Rödig H, Zeng-Brouwers J, Poluzzi C, Tascher G, Michaelis J, Lopez-Mosqueda J, Rhiner A, Huber LS, Diehl V, Dikic I, Kögel D, Münch C, Wygrecka M, Schaefer L
American journal of physiology. Cell physiology 2023 Feb 1;324(2):C339-C352
American journal of physiology. Cell physiology 2023 Feb 1;324(2):C339-C352
Ubiquitin-binding domain in ABIN1 is critical for regulating cell death and inflammation during development.
Li M, Liu Y, Xu C, Zhao Q, Liu J, Xing M, Li X, Zhang H, Wu X, Wang L, Ou Y, Wu X, Zhao X, Liu H, Qiu L, Li F, Li J, Rong W, Luo Y, Deng J, Wang X, Wang Z, Zhao Y, Lv A, Li Q, Zhang H
Cell death and differentiation 2022 Oct;29(10):2034-2045
Cell death and differentiation 2022 Oct;29(10):2034-2045
ABIN-1 is a key regulator in RIPK1-dependent apoptosis (RDA) and necroptosis, and ABIN-1 deficiency potentiates necroptosis-based cancer therapy in colorectal cancer.
Cai J, Hu D, Sakya J, Sun T, Wang D, Wang L, Mao X, Su Z
Cell death & disease 2021 Feb 1;12(2):140
Cell death & disease 2021 Feb 1;12(2):140
S100A6 promotes proliferation and migration of HepG2 cells via increased ubiquitin-dependent degradation of p53.
Song D, Xu B, Shi D, Li S, Cai Y
Open medicine (Warsaw, Poland) 2020;15(1):317-326
Open medicine (Warsaw, Poland) 2020;15(1):317-326
ABIN-1 protects chondrocytes from lipopolysaccharide-induced inflammatory injury through the inactivation of NF-κB signalling.
Peng K, Li Y, Lu C, Hu S
Clinical and experimental pharmacology & physiology 2020 Jul;47(7):1212-1220
Clinical and experimental pharmacology & physiology 2020 Jul;47(7):1212-1220
A20 and ABIN1 Suppression of a Keratinocyte Inflammatory Program with a Shared Single-Cell Expression Signature in Diverse Human Rashes.
Harirchian P, Lee J, Hilz S, Sedgewick AJ, Perez White BE, Kesling MJ, Mully T, Golovato J, Gray M, Mauro TM, Purdom E, Kim EA, Sbitany H, Bhutani T, Vaske CJ, Benz SC, Cho RJ, Cheng JB
The Journal of investigative dermatology 2019 Jun;139(6):1264-1273
The Journal of investigative dermatology 2019 Jun;139(6):1264-1273
ABIN1 inhibits HDAC1 ubiquitination and protects it from both proteasome- and lysozyme-dependent degradation.
Ma Y, Yuan S, Tian X, Lin S, Wei S, Hu T, Chen S, Li X, Chen S, Wu D, Wang M, Guo D
Journal of cellular biochemistry 2018 Apr;119(4):3030-3043
Journal of cellular biochemistry 2018 Apr;119(4):3030-3043
Immune regulator ABIN1 suppresses HIV-1 transcription by negatively regulating the ubiquitination of Tat.
Chen S, Yang X, Cheng W, Ma Y, Shang Y, Cao L, Chen S, Chen Y, Wang M, Guo D
Retrovirology 2017 Feb 13;14(1):12
Retrovirology 2017 Feb 13;14(1):12
A functional genomics screen for microRNA regulators of NF-kappaB signaling.
Olarerin-George AO, Anton L, Hwang YC, Elovitz MA, Hogenesch JB
BMC biology 2013 Feb 28;11:19
BMC biology 2013 Feb 28;11:19
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Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- HeLa cells were subjected to SDS PAGE followed by western blot with 15104-1-AP(TNIP1 antibody) at dilution of 1:1000
- Sample type
- cell line
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- Immunofluorescent analysis of Hela cells, using TNIP1 antibody 15104-1-AP at 1:25 dilution and Rhodamine-labeled goat anti-rabbit IgG (red).
- Sample type
- cell line
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- Immunohistochemical of paraffin-embedded human lymphoma using 15104-1-AP(TNIP1 antibody) at dilution of 1:50 (under 10x lens)
- Sample type
- tissue
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- Immunohistochemical of paraffin-embedded human lymphoma using 15104-1-AP(TNIP1 antibody) at dilution of 1:50 (under 40x lens)
- Sample type
- tissue
