Antibody data
- Antibody Data
- Antigen structure
- References [7]
- Comments [0]
- Validations
- Western blot [1]
- Immunohistochemistry [2]
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Validation data
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- Product number
- 16427-1-AP - Provider product page
- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#16427-1-AP, RRID:AB_1851434
- Product name
- PAN2 antibody
- Antibody type
- Polyclonal
- Description
- KD/KO validated PAN2 antibody (Cat. #16427-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse, rat and has been validated for the following applications: IF, IHC, WB,ELISA.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references Distinct Poly(A) nucleases have differential impact on sut-2 dependent tauopathy phenotypes.
YTHDF2/3 Are Required for Somatic Reprogramming through Different RNA Deadenylation Pathways.
Translation Efficiency and Degradation of ER-Associated mRNAs Modulated by ER-Anchored poly(A)-Specific Ribonuclease (PARN).
USP52 acts as a deubiquitinase and promotes histone chaperone ASF1A stabilization.
Mobilization of Dormant Cnot7 mRNA Promotes Deadenylation of Maternal Transcripts During Mouse Oocyte Maturation.
Anti-PABPC1 co-immunoprecipitation for examining the miRNAs directly targeting the 3'-UTR of EED mRNA.
An asymmetric PAN3 dimer recruits a single PAN2 exonuclease to mediate mRNA deadenylation and decay.
Kow RL, Strovas TJ, McMillan PJ, Jacobi AM, Behlke MA, Saxton AD, Latimer CS, Keene CD, Kraemer BC
Neurobiology of disease 2021 Jan;147:105148
Neurobiology of disease 2021 Jan;147:105148
YTHDF2/3 Are Required for Somatic Reprogramming through Different RNA Deadenylation Pathways.
Liu J, Gao M, Xu S, Chen Y, Wu K, Liu H, Wang J, Yang X, Wang J, Liu W, Bao X, Chen J
Cell reports 2020 Sep 8;32(10):108120
Cell reports 2020 Sep 8;32(10):108120
Translation Efficiency and Degradation of ER-Associated mRNAs Modulated by ER-Anchored poly(A)-Specific Ribonuclease (PARN).
Duan TL, Jiao H, He GJ, Yan YB
Cells 2020 Jan 9;9(1)
Cells 2020 Jan 9;9(1)
USP52 acts as a deubiquitinase and promotes histone chaperone ASF1A stabilization.
Yang S, Liu L, Cao C, Song N, Wang Y, Ma S, Zhang Q, Yu N, Ding X, Yang F, Tian S, Zhang K, Sun T, Yang J, Yao Z, Wu S, Shi L
Nature communications 2018 Mar 29;9(1):1285
Nature communications 2018 Mar 29;9(1):1285
Mobilization of Dormant Cnot7 mRNA Promotes Deadenylation of Maternal Transcripts During Mouse Oocyte Maturation.
Ma J, Fukuda Y, Schultz RM
Biology of reproduction 2015 Aug;93(2):48
Biology of reproduction 2015 Aug;93(2):48
Anti-PABPC1 co-immunoprecipitation for examining the miRNAs directly targeting the 3'-UTR of EED mRNA.
Hu Y, Yin KL, Ma X, Xia HF
PloS one 2014;9(8):e103695
PloS one 2014;9(8):e103695
An asymmetric PAN3 dimer recruits a single PAN2 exonuclease to mediate mRNA deadenylation and decay.
Jonas S, Christie M, Peter D, Bhandari D, Loh B, Huntzinger E, Weichenrieder O, Izaurralde E
Nature structural & molecular biology 2014 Jul;21(7):599-608
Nature structural & molecular biology 2014 Jul;21(7):599-608
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Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- NIH/3T3 cells were subjected to SDS PAGE followed by western blot with 16427-1-AP(PAN2 antibody) at dilution of 1:300
- Sample type
- cell line
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- Immunohistochemical of paraffin-embedded human heart using 16427-1-AP(PAN2 antibody) at dilution of 1:50 (under 10x lens)
- Sample type
- tissue
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- The PAN2 antibody from Proteintech is a rabbit polyclonal antibody to a recombinant protein of human PAN2. This antibody recognizes human, mouse, rat antigen. The PAN2 antibody has been validated for the following applications: ELISA, WB, IHC analysis.