Antibody data
- Antibody Data
- Antigen structure
- References [5]
- Comments [0]
- Validations
- Western blot [1]
- Immunocytochemistry [1]
- Immunoprecipitation [1]
- Immunohistochemistry [1]
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Validation data
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- Product number
- 12380-1-AP - Provider product page
- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#12380-1-AP, RRID:AB_2117222
- Product name
- HDGFRP3 antibody
- Antibody type
- Polyclonal
- Description
- KD/KO validated HDGFRP3 antibody (Cat. #12380-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse, rat and has been validated for the following applications: IF, IHC, IP, WB,ELISA.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references HDGFRP3 interaction with 53BP1 promotes DNA double-strand break repair.
A robust CD8(+) T cell-related classifier for predicting the prognosis and efficacy of immunotherapy in stage III lung adenocarcinoma.
A novel function of HRP-3 in regulating cell cycle progression via the HDAC-E2F1-Cyclin E pathway in lung cancer.
Knockdown of hepatoma-derived growth factor-related protein-3 induces apoptosis of H1299 cells via ROS-dependent and p53-independent NF-κB activation.
Depletion of hepatoma-derived growth factor-related protein-3 induces apoptotic sensitization of radioresistant A549 cells via reactive oxygen species-dependent p53 activation.
Zhang Z, Samsa WE, De Y, Zhang F, Reizes O, Almasan A, Gong Z
Nucleic acids research 2023 Mar 21;51(5):2238-2256
Nucleic acids research 2023 Mar 21;51(5):2238-2256
A robust CD8(+) T cell-related classifier for predicting the prognosis and efficacy of immunotherapy in stage III lung adenocarcinoma.
Feng J, Xu L, Zhang S, Geng L, Zhang T, Yu Y, Yuan R, He Y, Nan Z, Lin M, Guo H
Frontiers in immunology 2022;13:993187
Frontiers in immunology 2022;13:993187
A novel function of HRP-3 in regulating cell cycle progression via the HDAC-E2F1-Cyclin E pathway in lung cancer.
Yun HS, Lee J, Kim JY, Sim YJ, Lee CW, Park JK, Kim JS, Ahn J, Song JY, Baek JH, Hwang SG
Cancer science 2022 Jan;113(1):145-155
Cancer science 2022 Jan;113(1):145-155
Knockdown of hepatoma-derived growth factor-related protein-3 induces apoptosis of H1299 cells via ROS-dependent and p53-independent NF-κB activation.
Yun HS, Baek JH, Yim JH, Lee SJ, Lee CW, Song JY, Um HD, Park JK, Park IC, Hwang SG
Biochemical and biophysical research communications 2014 Jul 11;449(4):471-6
Biochemical and biophysical research communications 2014 Jul 11;449(4):471-6
Depletion of hepatoma-derived growth factor-related protein-3 induces apoptotic sensitization of radioresistant A549 cells via reactive oxygen species-dependent p53 activation.
Yun HS, Hong EH, Lee SJ, Baek JH, Lee CW, Yim JH, Um HD, Hwang SG
Biochemical and biophysical research communications 2013 Sep 27;439(3):333-9
Biochemical and biophysical research communications 2013 Sep 27;439(3):333-9
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Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- human brain tissue were subjected to SDS PAGE followed by western blot with 12380-1-AP(HDGFRP3 antibody) at dilution of 1:500
- Sample type
- tissue
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- Immunofluorescent analysis of MCF-7 cells, using HDGFRP3 antibody 12380-1-AP at 1:50 dilution and Rhodamine-labeled goat anti-rabbit IgG (red). Blue pseudocolor = DAPI (fluorescent DNA dye).
- Sample type
- cell line
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- IP Result of anti-HDGFRP3 (IP:12380-1-AP, 3ug; Detection:12380-1-AP 1:300) with mouse testis tissue lysate 4800ug.
- Sample type
- tissue
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- Immunohistochemical of paraffin-embedded human prostate cancer using 12380-1-AP(HDGFRP3 antibody) at dilution of 1:50 (under 10x lens)
- Sample type
- tissue