Antibody data
- Antibody Data
- Antigen structure
- References [5]
- Comments [0]
- Validations [0]
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- Product number
- HPA042968 - Provider product page
- Provider
- Atlas Antibodies
- Proper citation
- Atlas Antibodies Cat#HPA042968, RRID:AB_2678244
- Product name
- Anti-PAPD5
- Antibody type
- Polyclonal
- Description
- Polyclonal Antibody against Human PAPD5, Gene description: PAP associated domain containing 5, Alternative Gene Names: TRF4-2, Validated applications: IHC, Uniprot ID: Q8NDF8, Storage: Store at +4°C for short term storage. Long time storage is recommended at -20°C.
- Reactivity
- Human
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 100 µl
- Concentration
- 0.1 mg/ml
- Storage
- Store at +4°C for short term storage. Long time storage is recommended at -20°C.
- Handling
- The antibody solution should be gently mixed before use.
Submitted references Domain specific mutations in dyskerin disrupt 3' end processing of scaRNA13.
Host Poly(A) Polymerases PAPD5 and PAPD7 Provide Two Layers of Protection That Ensure the Integrity and Stability of Hepatitis B Virus RNA.
Small-Molecule PAPD5 Inhibitors Restore Telomerase Activity in Patient Stem Cells.
Disruption of Telomerase RNA Maturation Kinetics Precipitates Disease.
Inhibition of telomerase RNA decay rescues telomerase deficiency caused by dyskerin or PARN defects
Nagpal N, Tai AK, Nandakumar J, Agarwal S
Nucleic acids research 2022 Sep 9;50(16):9413-9425
Nucleic acids research 2022 Sep 9;50(16):9413-9425
Host Poly(A) Polymerases PAPD5 and PAPD7 Provide Two Layers of Protection That Ensure the Integrity and Stability of Hepatitis B Virus RNA.
Liu F, Lee ACH, Guo F, Kondratowicz AS, Micolochick Steuer HM, Miller A, Bailey LD, Wang X, Chen S, Kultgen SG, Cuconati A, Cole AG, Gotchev D, Dorsey BD, Rijnbrand R, Lam AM, Sofia MJ, Gao M
Journal of virology 2021 Aug 25;95(18):e0057421
Journal of virology 2021 Aug 25;95(18):e0057421
Small-Molecule PAPD5 Inhibitors Restore Telomerase Activity in Patient Stem Cells.
Nagpal N, Wang J, Zeng J, Lo E, Moon DH, Luk K, Braun RO, Burroughs LM, Keel SB, Reilly C, Lindsley RC, Wolfe SA, Tai AK, Cahan P, Bauer DE, Fong YW, Agarwal S
Cell stem cell 2020 Jun 4;26(6):896-909.e8
Cell stem cell 2020 Jun 4;26(6):896-909.e8
Disruption of Telomerase RNA Maturation Kinetics Precipitates Disease.
Roake CM, Chen L, Chakravarthy AL, Ferrell JE Jr, Raffa GD, Artandi SE
Molecular cell 2019 May 16;74(4):688-700.e3
Molecular cell 2019 May 16;74(4):688-700.e3
Inhibition of telomerase RNA decay rescues telomerase deficiency caused by dyskerin or PARN defects
Shukla S, Schmidt J, Goldfarb K, Cech T, Parker R
Nature Structural & Molecular Biology 2016;23(4):286-292
Nature Structural & Molecular Biology 2016;23(4):286-292
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