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Western blotAntibody data
- Antibody Data
- Antigen structure
- References [15]
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- Product number
- ABIN372653 - Provider product page
- Provider
- antibodies-online
- Product name
- anti-Glutamate Receptor, Ionotropic, AMPA 1 (GRIA1) (pSer845) antibody
- Antibody type
- Polyclonal
- Antigen
- Phosphopeptide corresponding to amino acid residues surrounding the phospho-Ser845 of GluR1.
- Description
- Sequential Chromatography on phospho- and dephosphopeptide affinity columns.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Epitope
- pSer845
- Isotype
- IgG
- Vial size
- 0.15 mL
- Storage
- Store the antibody undiluted (in aliquots) at-20°C or (in aliquots) at -80°C for long term.
- Handling
- Avoid repeated freezing and thawing.
Submitted references Melanocortin-4 receptor regulates hippocampal synaptic plasticity through a protein kinase A-dependent mechanism.
Dopamine- and cAMP-regulated phosphoprotein of 32-kDa (DARPP-32)-dependent activation of extracellular signal-regulated kinase (ERK) and mammalian target of rapamycin complex 1 (mTORC1) signaling in experimental parkinsonism.
Regulation of nucleus accumbens activity by the hypothalamic neuropeptide melanin-concentrating hormone.
PKA has a critical role in synaptic delivery of GluR1- and GluR4-containing AMPARs during initial stages of acquisition of in vitro classical conditioning.
Inhibition of mTOR signaling in Parkinson's disease prevents L-DOPA-induced dyskinesia.
CK2 negatively regulates Galphas signaling.
Distinct roles of PDE4 and PDE10A in the regulation of cAMP/PKA signaling in the striatum.
Long term synaptic depression that is associated with GluR1 dephosphorylation but not alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid (AMPA) receptor internalization.
Striatal dysregulation of Cdk5 alters locomotor responses to cocaine, motor learning, and dendritic morphology.
Postsynaptic protein phosphorylation and LTP.
Phosphorylation of the alpha-amino-3-hydroxy-5-methylisoxazole4-propionic acid receptor GluR1 subunit by calcium/calmodulin-dependent kinase II.
Characterization of multiple phosphorylation sites on the AMPA receptor GluR1 subunit.
Cloned glutamate receptors.
Phosphorylation and regulation of glutamate receptors by calcium/calmodulin-dependent protein kinase II.
A family of AMPA-selective glutamate receptors.
Shen Y, Fu WY, Cheng EY, Fu AK, Ip NY
The Journal of neuroscience : the official journal of the Society for Neuroscience 2013 Jan 9;33(2):464-72
The Journal of neuroscience : the official journal of the Society for Neuroscience 2013 Jan 9;33(2):464-72
Dopamine- and cAMP-regulated phosphoprotein of 32-kDa (DARPP-32)-dependent activation of extracellular signal-regulated kinase (ERK) and mammalian target of rapamycin complex 1 (mTORC1) signaling in experimental parkinsonism.
Santini E, Feyder M, Gangarossa G, Bateup HS, Greengard P, Fisone G
The Journal of biological chemistry 2012 Aug 10;287(33):27806-12
The Journal of biological chemistry 2012 Aug 10;287(33):27806-12
Regulation of nucleus accumbens activity by the hypothalamic neuropeptide melanin-concentrating hormone.
Sears RM, Liu RJ, Narayanan NS, Sharf R, Yeckel MF, Laubach M, Aghajanian GK, DiLeone RJ
The Journal of neuroscience : the official journal of the Society for Neuroscience 2010 Jun 16;30(24):8263-73
The Journal of neuroscience : the official journal of the Society for Neuroscience 2010 Jun 16;30(24):8263-73
PKA has a critical role in synaptic delivery of GluR1- and GluR4-containing AMPARs during initial stages of acquisition of in vitro classical conditioning.
Zheng Z, Keifer J
Journal of neurophysiology 2009 May;101(5):2539-49
Journal of neurophysiology 2009 May;101(5):2539-49
Inhibition of mTOR signaling in Parkinson's disease prevents L-DOPA-induced dyskinesia.
Santini E, Heiman M, Greengard P, Valjent E, Fisone G
Science signaling 2009 Jul 21;2(80):ra36
Science signaling 2009 Jul 21;2(80):ra36
CK2 negatively regulates Galphas signaling.
Rebholz H, Nishi A, Liebscher S, Nairn AC, Flajolet M, Greengard P
Proceedings of the National Academy of Sciences of the United States of America 2009 Aug 18;106(33):14096-101
Proceedings of the National Academy of Sciences of the United States of America 2009 Aug 18;106(33):14096-101
Distinct roles of PDE4 and PDE10A in the regulation of cAMP/PKA signaling in the striatum.
Nishi A, Kuroiwa M, Miller DB, O'Callaghan JP, Bateup HS, Shuto T, Sotogaku N, Fukuda T, Heintz N, Greengard P, Snyder GL
The Journal of neuroscience : the official journal of the Society for Neuroscience 2008 Oct 15;28(42):10460-71
The Journal of neuroscience : the official journal of the Society for Neuroscience 2008 Oct 15;28(42):10460-71
Long term synaptic depression that is associated with GluR1 dephosphorylation but not alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid (AMPA) receptor internalization.
Davies KD, Goebel-Goody SM, Coultrap SJ, Browning MD
The Journal of biological chemistry 2008 Nov 28;283(48):33138-46
The Journal of biological chemistry 2008 Nov 28;283(48):33138-46
Striatal dysregulation of Cdk5 alters locomotor responses to cocaine, motor learning, and dendritic morphology.
Meyer DA, Richer E, Benkovic SA, Hayashi K, Kansy JW, Hale CF, Moy LY, Kim Y, O'Callaghan JP, Tsai LH, Greengard P, Nairn AC, Cowan CW, Miller DB, Antich P, Bibb JA
Proceedings of the National Academy of Sciences of the United States of America 2008 Nov 25;105(47):18561-6
Proceedings of the National Academy of Sciences of the United States of America 2008 Nov 25;105(47):18561-6
Postsynaptic protein phosphorylation and LTP.
Soderling TR, Derkach VA
Trends in neurosciences 2000 Feb;23(2):75-80
Trends in neurosciences 2000 Feb;23(2):75-80
Phosphorylation of the alpha-amino-3-hydroxy-5-methylisoxazole4-propionic acid receptor GluR1 subunit by calcium/calmodulin-dependent kinase II.
Mammen AL, Kameyama K, Roche KW, Huganir RL
The Journal of biological chemistry 1997 Dec 19;272(51):32528-33
The Journal of biological chemistry 1997 Dec 19;272(51):32528-33
Characterization of multiple phosphorylation sites on the AMPA receptor GluR1 subunit.
Roche KW, O'Brien RJ, Mammen AL, Bernhardt J, Huganir RL
Neuron 1996 Jun;16(6):1179-88
Neuron 1996 Jun;16(6):1179-88
Cloned glutamate receptors.
Hollmann M, Heinemann S
Annual review of neuroscience 1994;17:31-108
Annual review of neuroscience 1994;17:31-108
Phosphorylation and regulation of glutamate receptors by calcium/calmodulin-dependent protein kinase II.
McGlade-McCulloh E, Yamamoto H, Tan SE, Brickey DA, Soderling TR
Nature 1993 Apr 15;362(6421):640-2
Nature 1993 Apr 15;362(6421):640-2
A family of AMPA-selective glutamate receptors.
Keinänen K, Wisden W, Sommer B, Werner P, Herb A, Verdoorn TA, Sakmann B, Seeburg PH
Science (New York, N.Y.) 1990 Aug 3;249(4968):556-60
Science (New York, N.Y.) 1990 Aug 3;249(4968):556-60
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