Antibody data
- Antibody Data
- Antigen structure
- References [33]
- Comments [0]
- Validations [0]
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- Product number
- 67642-1-Ig - Provider product page

- Provider
- Proteintech Group
- Product name
- GRIA1 antibody
- Antibody type
- Monoclonal
- Description
- GRIA1 antibody (Cat. #67642-1-Ig) is a mouse monoclonal antibody that shows reactivity with Human, Pig, Mouse, Rat, Rabbit and has been validated for the following applications: IF, IHC, WB,ELISA.
- Reactivity
- Human, Mouse, Rat, Porcine, Rabbit
- Host
- Mouse
- Conjugate
- Unconjugated
- Isotype
- IgG
- Antibody clone number
- 1F4A1
- Vial size
- 20ul, 150ul
Submitted references Biphasic response of silent synapses: Differential remodeling of hippocampal synaptic plasticity by status epilepticus in juvenile versus adult mice.
Discovery of Novel Pyrano[3,2-a]carbazole Alkaloid Derivatives against Ischemic Stroke by Targeting ADGRL3.
The dynamic impairment of synaptic transmission in the PCx-IL engram circuit contributes to early olfactory memory decline in Alzheimer's disease.
Bufotenidine attenuates astrocyte ferroptosis in depressive-like behaviors through targeting GluA1 to reduce neuronal lipid synthesis.
Targeted fecal microbiota transplantation ameliorates autism-like behaviors via gut-brain axis and excitatory/inhibitory balance restoration in a propionic acid mouse model.
GRIA1 regulates TGN export and secretion of Sonic hedgehog.
Ketogenic diet can inhibit epileptic seizures by inhibiting RGMa methylation to promote GluA1 palmitoylation in the epileptic rat model.
Kai-Xin-San Has Antidepressant-Like Effect in Tricyclic Antidepressant Treatment Resistant Animal Model by Rebalancing Tryptophan Metabolism.
Antidepressant effects of total phenols and total saponins of Kai-Xin-San mediated by synaptic plasticity induced by BDNF/TrkB/Akt pathway.
USP47 Regulates Excitatory Synaptic Plasticity and Modulates Seizures in Murine Models by Blocking Ubiquitinated AMPAR Degradation.
Network Dysfunction Precedes Neurodegeneration in a dox-Regulatable TDP-43 Mouse Model of ALS-FTD.
Allele-Specific Regulation of PAXIP1-AS1 by SMC3/CEBPB at rs112651172 in Psychiatric Disorders Drives Synaptic and Behavioral Dysfunctions in Mice.
Long-term variable photoperiod exposure impairs hippocampal synapse involving of the glutamate system and leads to memory deficits in male Wistar rats.
Neurotransmitter imbalance and amygdala synaptic plasticity in lumbar disc herniation-induced chronic pain and related emotional Disturbances:A multi-omics analysis.
Cpeb1 remodels cell type-specific translational program to promote fear extinction.
Cortex-Specific Tmem169 Deficiency Induces Defects in Cortical Neuron Development and Autism-Like Behaviors in Mice.
Microglial-derived nitric oxide regulates amygdala synaptic plasticity to drive chronic pain and depression induced by lumbar disc herniation.
Dynamic changes of excitatory and inhibitory synapses in layer II/III of the primary motor cortex after peripheral nerve repair.
Follicle-stimulating hormone induces depression-like phenotype by affecting synaptic function.
A tripartite circRNA/mRNA/miRNA interaction regulates glutamatergic signaling in the mouse brain.
Increased expression of mesencephalic astrocyte-derived neurotrophic factor (MANF) contributes to synapse loss in Alzheimer's disease.
SorCS2 is involved in promoting periodontitis-induced depression-like behaviour in mice.
The decreased astrocyte-microglia interaction reflects the early characteristics of Alzheimer's disease.
Sorbs2 regulates seizure activity by influencing AMPAR-mediated excitatory synaptic transmission in temporal lobe epilepsy.
[Tacrolimus Induces Pain by Upregulating the Synaptic Expression of AMPA Receptors in the Spinal Cord Dorsal Horn].
Low-dose diazepam improves cognitive function in APP/PS1 mouse models: Involvement of AMPA receptors.
Postsynaptic lncRNA Sera/Pkm2 pathway orchestrates the transition from social competition to rank by remodeling the neural ensemble in mPFC.
Integrin α3 is required for high-frequency repetitive transcranial magnetic stimulation-induced glutamatergic synaptic transmission in mice with ischemia.
Inhibition of ANXA2 activity attenuates epileptic susceptibility and GluA1 phosphorylation.
Amelioration of olfactory dysfunction in a mouse model of Parkinson's disease via enhancing GABAergic signaling.
Hippocampal AMPA receptors mediate the impairment of spatial learning and memory in prenatally stressed offspring rats.
Long-term variable photoperiod exposure impairs the mPFC and induces anxiety and depression-like behavior in male wistar rats.
Rapid antidepressant-like effect of Fructus Aurantii depends on cAMP-response element binding protein/Brain-derived neurotrophic facto by mediating synaptic transmission.
Dai J, Zeng Q, Cheng L, Chen H, Jiang L, Hu Y
Neurochemistry international 2026 May;195:106147
Neurochemistry international 2026 May;195:106147
Discovery of Novel Pyrano[3,2-a]carbazole Alkaloid Derivatives against Ischemic Stroke by Targeting ADGRL3.
Tao A, Lin Y, Feng J, Luo H, Qu K, Kang Y, Yu H, Chuangjun L, Ma J, Huang W, Sheng L, Zhang D, Zang Y, Peng Y
Journal of medicinal chemistry 2026 Mar 26;69(6):7012-7031
Journal of medicinal chemistry 2026 Mar 26;69(6):7012-7031
The dynamic impairment of synaptic transmission in the PCx-IL engram circuit contributes to early olfactory memory decline in Alzheimer's disease.
Yan Y, Song D, Li G, Li J, Tang Y, Li D, Mao J, Li H, Liu X, Yu D, Ma F, Pang Y, Jin Y, Deng Y, Qiu Y, Quan Z, Ni J, Cheng Y, Wang Z, Dong Z, Hong Q
Molecular psychiatry 2026 Mar 25;
Molecular psychiatry 2026 Mar 25;
Bufotenidine attenuates astrocyte ferroptosis in depressive-like behaviors through targeting GluA1 to reduce neuronal lipid synthesis.
Wu W, Chen Z, Xu Y, Xie X, Tan A, Hu M, Xu D, Lv X, Chen W, Zhou J, Zhu Y, Ma H
Free radical biology & medicine 2026 Jun;249:589-602
Free radical biology & medicine 2026 Jun;249:589-602
Targeted fecal microbiota transplantation ameliorates autism-like behaviors via gut-brain axis and excitatory/inhibitory balance restoration in a propionic acid mouse model.
He J, Lin Z, Lin X, Wang C, Cao M, Xia R, Hong W
Brain, behavior, and immunity 2026 Jan;131:106162
Brain, behavior, and immunity 2026 Jan;131:106162
GRIA1 regulates TGN export and secretion of Sonic hedgehog.
Tang X, Tian Y, Wang Q, Song Z, Zhao X, Guo Y
The Journal of biological chemistry 2026 Feb;302(2):111084
The Journal of biological chemistry 2026 Feb;302(2):111084
Ketogenic diet can inhibit epileptic seizures by inhibiting RGMa methylation to promote GluA1 palmitoylation in the epileptic rat model.
Xu J, Huo L, Liu J, Xu W, Yu T
Nutrition & metabolism 2026 Feb 5;23(1):30
Nutrition & metabolism 2026 Feb 5;23(1):30
Kai-Xin-San Has Antidepressant-Like Effect in Tricyclic Antidepressant Treatment Resistant Animal Model by Rebalancing Tryptophan Metabolism.
Yao L, Chen C, Jing R, Wang CC, Wang YB, Li X, Mu LH, Yin H, Liu P, Hu Y
Chinese journal of integrative medicine 2026 Apr;32(4):322-331
Chinese journal of integrative medicine 2026 Apr;32(4):322-331
Antidepressant effects of total phenols and total saponins of Kai-Xin-San mediated by synaptic plasticity induced by BDNF/TrkB/Akt pathway.
Tang YN, Bai YF, Dong A, Rao QL, Wu HH, Wang CG, Xu YT
Journal of ethnopharmacology 2025 Sep 25;353(Pt B):120423
Journal of ethnopharmacology 2025 Sep 25;353(Pt B):120423
USP47 Regulates Excitatory Synaptic Plasticity and Modulates Seizures in Murine Models by Blocking Ubiquitinated AMPAR Degradation.
Yang J, Zhang H, Wang Y, Luo Y, Zheng W, Liu Y, Jiang Q, Deng J, Liu Q, Zhang P, Huang H, Yu C, Xu Z, Chen Y
Neuroscience bulletin 2025 Oct;41(10):1805-1823
Neuroscience bulletin 2025 Oct;41(10):1805-1823
Network Dysfunction Precedes Neurodegeneration in a dox-Regulatable TDP-43 Mouse Model of ALS-FTD.
Rodemer W, Ra I, Gujral J, Jia E, Juul H, Zhang B, Hoxha K, Xing B, Mehta S, Farag M, Rekulak S, Porta S, Jensen FE, Talos DM, Lee VM
The Journal of neuroscience : the official journal of the Society for Neuroscience 2025 Oct 8;45(41)
The Journal of neuroscience : the official journal of the Society for Neuroscience 2025 Oct 8;45(41)
Allele-Specific Regulation of PAXIP1-AS1 by SMC3/CEBPB at rs112651172 in Psychiatric Disorders Drives Synaptic and Behavioral Dysfunctions in Mice.
Ni C, Chen H, Chen Q, Liao Y, Wang Y, Ye L, Wu X, Ni H, Jiang T, Li S, Yang Q, Xue H, Wang Z, Yi F, Zhao C
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2025 Nov;12(44):e08259
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2025 Nov;12(44):e08259
Long-term variable photoperiod exposure impairs hippocampal synapse involving of the glutamate system and leads to memory deficits in male Wistar rats.
Hou Y, Zuo Y, Song S, Zhang T
Experimental neurology 2025 May;387:115191
Experimental neurology 2025 May;387:115191
Neurotransmitter imbalance and amygdala synaptic plasticity in lumbar disc herniation-induced chronic pain and related emotional Disturbances:A multi-omics analysis.
Huang Z, Tan H, Fu Y, Xie H, Tan H, Gao K, Lou H
Neuropharmacology 2025 Jun 15;271:110405
Neuropharmacology 2025 Jun 15;271:110405
Cpeb1 remodels cell type-specific translational program to promote fear extinction.
Zhang J, Yang CQ, Liu ZQ, Wu SP, Li ZG, Zhang LM, Fan HW, Guo ZY, Man HY, Li X, Lu YM, Zhu LQ, Liu D
Science advances 2025 Jan 10;11(2):eadr8687
Science advances 2025 Jan 10;11(2):eadr8687
Cortex-Specific Tmem169 Deficiency Induces Defects in Cortical Neuron Development and Autism-Like Behaviors in Mice.
Wang J, Zhang J, Li J, Gao Q, Chen J, Jia C, Gu X
The Journal of neuroscience : the official journal of the Society for Neuroscience 2025 Feb 26;45(9)
The Journal of neuroscience : the official journal of the Society for Neuroscience 2025 Feb 26;45(9)
Microglial-derived nitric oxide regulates amygdala synaptic plasticity to drive chronic pain and depression induced by lumbar disc herniation.
Huang Z, Sun J, Li H, Hu Z, Tan H, Fu Y, Gao L, Peng X, Lou H
Neuropharmacology 2025 Dec 1;280:110662
Neuropharmacology 2025 Dec 1;280:110662
Dynamic changes of excitatory and inhibitory synapses in layer II/III of the primary motor cortex after peripheral nerve repair.
Song J, Yusufu A, Sun J, Zhou H, Chen H, Liu D, Zhang Q, Li L
Neuroscience 2025 Apr 19;572:204-213
Neuroscience 2025 Apr 19;572:204-213
Follicle-stimulating hormone induces depression-like phenotype by affecting synaptic function.
Huang L, Sun S, Jiang G, Xie G, Yang Y, Chen S, Luo J, Lv C, Li X, Liao J, Wang Z, Zhang Z, Xiong J
Frontiers in molecular neuroscience 2024;17:1459858
Frontiers in molecular neuroscience 2024;17:1459858
A tripartite circRNA/mRNA/miRNA interaction regulates glutamatergic signaling in the mouse brain.
Silenzi V, D'Ambra E, Santini T, D'Uva S, Setti A, Salvi N, Nicoletti C, Scarfò R, Cordella F, Mongiardi B, Cavezza D, Liessi N, Ferrucci L, Ragozzino D, Armirotti A, Di Angelantonio S, De Leonibus E, Bozzoni I, Morlando M
Cell reports 2024 Oct 22;43(10):114766
Cell reports 2024 Oct 22;43(10):114766
Increased expression of mesencephalic astrocyte-derived neurotrophic factor (MANF) contributes to synapse loss in Alzheimer's disease.
Zhang Y, Chen X, Chen L, Shao M, Zhu W, Xing T, Guo T, Jia Q, Yang H, Yin P, Yan XX, Yu J, Li S, Li XJ, Yang S
Molecular neurodegeneration 2024 Oct 18;19(1):75
Molecular neurodegeneration 2024 Oct 18;19(1):75
SorCS2 is involved in promoting periodontitis-induced depression-like behaviour in mice.
Li Y, Yang Y, Guan X, Liu Z, Pan L, Wang Y, Jia X, Yang J, Hou T
Oral diseases 2024 Nov;30(8):5408-5420
Oral diseases 2024 Nov;30(8):5408-5420
The decreased astrocyte-microglia interaction reflects the early characteristics of Alzheimer's disease.
Liu K, Aierken A, Liu M, Parhat N, Kong W, Yin X, Liu G, Yu D, Hong J, Ni J, Quan Z, Liu X, Ji S, Mao J, Peng W, Chen C, Yan Y, Qing H
iScience 2024 Mar 15;27(3):109281
iScience 2024 Mar 15;27(3):109281
Sorbs2 regulates seizure activity by influencing AMPAR-mediated excitatory synaptic transmission in temporal lobe epilepsy.
Ban Y, Yang X, Tan D, Gong C, Gao Y, Yuan J, Chen Y, Wang Y, Xu T
Neurochemistry international 2024 Jun;176:105727
Neurochemistry international 2024 Jun;176:105727
[Tacrolimus Induces Pain by Upregulating the Synaptic Expression of AMPA Receptors in the Spinal Cord Dorsal Horn].
Xu J, Li J, Li Y, Wang K, Zeng X, Suo Z
Sichuan da xue xue bao. Yi xue ban = Journal of Sichuan University. Medical science edition 2024 Jan 20;55(1):132-138
Sichuan da xue xue bao. Yi xue ban = Journal of Sichuan University. Medical science edition 2024 Jan 20;55(1):132-138
Low-dose diazepam improves cognitive function in APP/PS1 mouse models: Involvement of AMPA receptors.
Chen J, Zhang M, Shen Z, Tang M, Zeng Y, Bai D, Zhao P, Jiang G
Brain research 2024 Dec 15;1845:149207
Brain research 2024 Dec 15;1845:149207
Postsynaptic lncRNA Sera/Pkm2 pathway orchestrates the transition from social competition to rank by remodeling the neural ensemble in mPFC.
Zhu LS, Lai C, Zhou CW, Chen HY, Liu ZQ, Guo Z, Man H, Du HY, Lu Y, Hu F, Chen Z, Shu K, Zhu LQ, Liu D
Cell discovery 2024 Aug 20;10(1):87
Cell discovery 2024 Aug 20;10(1):87
Integrin α3 is required for high-frequency repetitive transcranial magnetic stimulation-induced glutamatergic synaptic transmission in mice with ischemia.
Liu L, Hu H, Wu J, Koleske AJ, Chen H, Wang N, Yu K, Wu Y, Xiao X, Zhang Q
CNS neuroscience & therapeutics 2024 Apr;30(4):e14498
CNS neuroscience & therapeutics 2024 Apr;30(4):e14498
Inhibition of ANXA2 activity attenuates epileptic susceptibility and GluA1 phosphorylation.
Ma L, Wu Q, Yuan J, Wang Y, Zhang P, Liu Q, Tan D, Liang M, Chen Y
CNS neuroscience & therapeutics 2023 Nov;29(11):3644-3656
CNS neuroscience & therapeutics 2023 Nov;29(11):3644-3656
Amelioration of olfactory dysfunction in a mouse model of Parkinson's disease via enhancing GABAergic signaling.
Liu XY, Wang K, Deng XH, Wei YH, Guo R, Liu SF, Zhu YF, Zhong JJ, Zheng JY, Wang MD, Ye QH, He JQ, Guo KH, Zhu JR, Huang SQ, Chen ZX, Lv CS, Wen L
Cell & bioscience 2023 Jun 3;13(1):101
Cell & bioscience 2023 Jun 3;13(1):101
Hippocampal AMPA receptors mediate the impairment of spatial learning and memory in prenatally stressed offspring rats.
Yao D, Mu Y, Lu Y, Li L, Shao S, Zhou J, Li J, Chen S, Zhang D, Zhang Y, Zhu Z, Li H
Journal of psychiatric research 2022 Jul;151:17-24
Journal of psychiatric research 2022 Jul;151:17-24
Long-term variable photoperiod exposure impairs the mPFC and induces anxiety and depression-like behavior in male wistar rats.
Hou Y, Wang Y, Song S, Zuo Y, Zhang H, Bai C, Zhao H, Zhang T
Experimental neurology 2022 Jan;347:113908
Experimental neurology 2022 Jan;347:113908
Rapid antidepressant-like effect of Fructus Aurantii depends on cAMP-response element binding protein/Brain-derived neurotrophic facto by mediating synaptic transmission.
Wu L, Zhang T, Chen K, Lu C, Liu XF, Zhou JL, Huang YK, Yan H, Chen Y, Zhang CJ, Li JF, Shi SQ, Ren P, Huang X
Phytotherapy research : PTR 2021 Jan;35(1):404-414
Phytotherapy research : PTR 2021 Jan;35(1):404-414
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