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ImmunohistochemistryAntibody data
- Antibody Data
- Antigen structure
- References [14]
- Comments [0]
- Validations
- Immunohistochemistry [1]
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- Product number
- PA1-37776 - Provider product page
- Provider
- Invitrogen Antibodies
- Product name
- Anti-GluR1 Polyclonal Antibody
- Antibody type
- Polyclonal
- Antigen
- Synthetic peptide
- Description
- This antibody is predicted to react with bovine, chicken, canine, amphibian, mouse, rabbit and rat based on sequence homology. Heat-mediated antigen retrieval is recommended prior to staining, using a 10mM citrate buffer, pH 6.0, for 10 minutes followed by cooling at room temperature for 20 min. Following antigen retrieval, incubate samples with primary antibody for 30 min at room temperature. A suggested positive control is brain tissue.
- Reactivity
- Human
- Host
- Rabbit
- Isotype
- IgG
- Vial size
- 1 mL
- Concentration
- Lot Dependent
- Storage
- 4° C, do not freeze
Submitted references Nucleus Accumbens AMPA Receptors Are Necessary for Morphine-Withdrawal-Induced Negative-Affective States in Rats.
Eating 'Junk-Food' Produces Rapid and Long-Lasting Increases in NAc CP-AMPA Receptors: Implications for Enhanced Cue-Induced Motivation and Food Addiction.
AMPA receptor upregulation in the nucleus accumbens shell of cocaine-sensitized rats depends upon S-nitrosylation of stargazin.
BDNF contributes to both rapid and homeostatic alterations in AMPA receptor surface expression in nucleus accumbens medium spiny neurons.
Kalirin-7 mediates cocaine-induced AMPA receptor and spine plasticity, enabling incentive sensitization.
Different roles of BDNF in nucleus accumbens core versus shell during the incubation of cue-induced cocaine craving and its long-term maintenance.
Local potentiation of excitatory synapses by serotonin and its alteration in rodent models of depression.
A protein cross-linking assay for measuring cell surface expression of glutamate receptor subunits in the rodent brain after in vivo treatments.
Distribution of AMPA receptor subunits and TARPs in synaptic and extrasynaptic membranes of the adult rat nucleus accumbens.
Brain-derived neurotrophic factor rapidly increases AMPA receptor surface expression in rat nucleus accumbens.
Effects of acute cocaine or dopamine receptor agonists on AMPA receptor distribution in the rat nucleus accumbens.
Quantitative analysis of AMPA receptor subunit composition in addiction-related brain regions.
Alterations in AMPA receptor subunits and TARPs in the rat nucleus accumbens related to the formation of Ca²⁺-permeable AMPA receptors during the incubation of cocaine craving.
Calcium-permeable AMPA receptors are present in nucleus accumbens synapses after prolonged withdrawal from cocaine self-administration but not experimenter-administered cocaine.
Russell SE, Puttick DJ, Sawyer AM, Potter DN, Mague S, Carlezon WA Jr, Chartoff EH
The Journal of neuroscience : the official journal of the Society for Neuroscience 2016 May 25;36(21):5748-62
The Journal of neuroscience : the official journal of the Society for Neuroscience 2016 May 25;36(21):5748-62
Eating 'Junk-Food' Produces Rapid and Long-Lasting Increases in NAc CP-AMPA Receptors: Implications for Enhanced Cue-Induced Motivation and Food Addiction.
Oginsky MF, Goforth PB, Nobile CW, Lopez-Santiago LF, Ferrario CR
Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 2016 Dec;41(13):2977-2986
Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 2016 Dec;41(13):2977-2986
AMPA receptor upregulation in the nucleus accumbens shell of cocaine-sensitized rats depends upon S-nitrosylation of stargazin.
Selvakumar B, Campbell PW, Milovanovic M, Park DJ, West AR, Snyder SH, Wolf ME
Neuropharmacology 2014 Feb;77:28-38
Neuropharmacology 2014 Feb;77:28-38
BDNF contributes to both rapid and homeostatic alterations in AMPA receptor surface expression in nucleus accumbens medium spiny neurons.
Reimers JM, Loweth JA, Wolf ME
The European journal of neuroscience 2014 Apr;39(7):1159-69
The European journal of neuroscience 2014 Apr;39(7):1159-69
Kalirin-7 mediates cocaine-induced AMPA receptor and spine plasticity, enabling incentive sensitization.
Wang X, Cahill ME, Werner CT, Christoffel DJ, Golden SA, Xie Z, Loweth JA, Marinelli M, Russo SJ, Penzes P, Wolf ME
The Journal of neuroscience : the official journal of the Society for Neuroscience 2013 Jul 3;33(27):11012-22
The Journal of neuroscience : the official journal of the Society for Neuroscience 2013 Jul 3;33(27):11012-22
Different roles of BDNF in nucleus accumbens core versus shell during the incubation of cue-induced cocaine craving and its long-term maintenance.
Li X, DeJoseph MR, Urban JH, Bahi A, Dreyer JL, Meredith GE, Ford KA, Ferrario CR, Loweth JA, Wolf ME
The Journal of neuroscience : the official journal of the Society for Neuroscience 2013 Jan 16;33(3):1130-42
The Journal of neuroscience : the official journal of the Society for Neuroscience 2013 Jan 16;33(3):1130-42
Local potentiation of excitatory synapses by serotonin and its alteration in rodent models of depression.
Cai X, Kallarackal AJ, Kvarta MD, Goluskin S, Gaylor K, Bailey AM, Lee HK, Huganir RL, Thompson SM
Nature neuroscience 2013 Apr;16(4):464-72
Nature neuroscience 2013 Apr;16(4):464-72
A protein cross-linking assay for measuring cell surface expression of glutamate receptor subunits in the rodent brain after in vivo treatments.
Boudreau AC, Milovanovic M, Conrad KL, Nelson C, Ferrario CR, Wolf ME
Current protocols in neuroscience 2012 Apr;Chapter 5:Unit 5.30.1-19
Current protocols in neuroscience 2012 Apr;Chapter 5:Unit 5.30.1-19
Distribution of AMPA receptor subunits and TARPs in synaptic and extrasynaptic membranes of the adult rat nucleus accumbens.
Ferrario CR, Loweth JA, Milovanovic M, Wang X, Wolf ME
Neuroscience letters 2011 Mar 3;490(3):180-4
Neuroscience letters 2011 Mar 3;490(3):180-4
Brain-derived neurotrophic factor rapidly increases AMPA receptor surface expression in rat nucleus accumbens.
Li X, Wolf ME
The European journal of neuroscience 2011 Jul;34(2):190-8
The European journal of neuroscience 2011 Jul;34(2):190-8
Effects of acute cocaine or dopamine receptor agonists on AMPA receptor distribution in the rat nucleus accumbens.
Ferrario CR, Li X, Wolf ME
Synapse (New York, N.Y.) 2011 Jan;65(1):54-63
Synapse (New York, N.Y.) 2011 Jan;65(1):54-63
Quantitative analysis of AMPA receptor subunit composition in addiction-related brain regions.
Reimers JM, Milovanovic M, Wolf ME
Brain research 2011 Jan 7;1367:223-33
Brain research 2011 Jan 7;1367:223-33
Alterations in AMPA receptor subunits and TARPs in the rat nucleus accumbens related to the formation of Ca²⁺-permeable AMPA receptors during the incubation of cocaine craving.
Ferrario CR, Loweth JA, Milovanovic M, Ford KA, Galiñanes GL, Heng LJ, Tseng KY, Wolf ME
Neuropharmacology 2011 Dec;61(7):1141-51
Neuropharmacology 2011 Dec;61(7):1141-51
Calcium-permeable AMPA receptors are present in nucleus accumbens synapses after prolonged withdrawal from cocaine self-administration but not experimenter-administered cocaine.
McCutcheon JE, Wang X, Tseng KY, Wolf ME, Marinelli M
The Journal of neuroscience : the official journal of the Society for Neuroscience 2011 Apr 13;31(15):5737-43
The Journal of neuroscience : the official journal of the Society for Neuroscience 2011 Apr 13;31(15):5737-43
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Supportive validation
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- Invitrogen Antibodies (provider)
- Main image
- Experimental details
- Immunohistochemical analysis of GluR1 using a polyclonal antibody (Product # PA1-37776).
