APR02525G
antibody from Leading Biology
Targeting: NOD2
BLAU, CARD15, CD, CLR16.3, IBD1, NLRC2, PSORAS1
Antibody data
- Antibody Data
- Antigen structure
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- Product number
- APR02525G - Provider product page
- Provider
- Leading Biology
- Product name
- NOD2 / CARD15 Antibody (C-Terminus)
- Antibody type
- Polyclonal
- Description
- Recognizes muramyl dipeptide (MDP) constituents of bacterial peptidoglycans and plays a key role in gastrointestinal immunity: upon stimulation, binds the proximal adapter receptor- interacting RIPK2, which recruits ubiquitin ligases as XIAP, BIRC2, BIRC3 and the LUBAC complex, triggering activation of MAP kinases and activation of NF-kappa-B signaling, leading to activate the transcription of hundreds of genes involved in immune response.
- Reactivity
- Human
- Host
- Rabbit
- Storage
- Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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