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Learn20980-1-AP
antibody from Proteintech Group
Targeting: NOD2
BLAU, CARD15, CD, CLR16.3, IBD1, NLRC2, PSORAS1
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- Antibody Data
- Antigen structure
- References [16]
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- Validations
- Western blot [1]
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- Product number
- 20980-1-AP - Provider product page
- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#20980-1-AP, RRID:AB_10949226
- Product name
- NOD2 antibody
- Antibody type
- Polyclonal
- Description
- NOD2 antibody (Cat. #20980-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse and has been validated for the following applications: ELISA.
- Reactivity
- Human, Mouse
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references NOD2 contributes to Parvimonas micra-induced bone resorption in diabetic rats with experimental periodontitis.
Selective autophagy of RIPosomes maintains innate immune homeostasis during bacterial infection.
NOD2 deficiency confers a pro-tumorigenic macrophage phenotype to promote lung adenocarcinoma progression.
NOD2 inhibits tumorigenesis and increases chemosensitivity of hepatocellular carcinoma by targeting AMPK pathway.
Effects of peptidoglycan on the development of steatohepatitis.
The expression of NOD2, NLRP3 and NLRC5 and renal injury in anti-neutrophil cytoplasmic antibody-associated vasculitis.
The synergistic effect of NOD2 and TLR4 on the activation of autophagy in human submandibular gland inflammation.
NOD2 promotes dopaminergic degeneration regulated by NADPH oxidase 2 in 6-hydroxydopamine model of Parkinson's disease.
NOD2-RIP2 contributes to the inflammatory responses of mice in vivo to Streptococcus pneumoniae.
NOD2 promotes endothelial-to-mesenchymal transition of glomerular endothelial cells via MEK/ERK signaling pathway in diabetic nephropathy.
17β-Estradiol and progesterone decrease MDP induced NOD2 expression in bovine mammary epithelial cells.
Progranulin protects against renal ischemia/reperfusion injury in mice.
Identification of NOD2 as a novel target of RNA-binding protein HuR: evidence from NADPH oxidase-mediated HuR signaling in diabetic nephropathy.
NOD2 deficiency protects against cardiac remodeling after myocardial infarction in mice.
Novel role of NOD2 in mediating Ca2+ signaling: evidence from NOD2-regulated podocyte TRPC6 channels in hyperhomocysteinemia.
NOD2 promotes renal injury by exacerbating inflammation and podocyte insulin resistance in diabetic nephropathy.
Chen YY, Tan L, Su XL, Chen NX, Liu Q, Feng YZ, Guo Y
Molecular oral microbiology 2024 Dec;39(6):446-460
Molecular oral microbiology 2024 Dec;39(6):446-460
Selective autophagy of RIPosomes maintains innate immune homeostasis during bacterial infection.
Mehto S, Jena KK, Yadav R, Priyadarsini S, Samal P, Krishna S, Dhar K, Jain A, Chauhan NR, Murmu KC, Bal R, Sahu R, Jaiswal P, Sahoo BS, Patnaik S, Kufer TA, Rusten TE, Chauhan S, Prasad P, Chauhan S
The EMBO journal 2022 Dec 1;41(23):e111289
The EMBO journal 2022 Dec 1;41(23):e111289
NOD2 deficiency confers a pro-tumorigenic macrophage phenotype to promote lung adenocarcinoma progression.
Wang Y, Miao Z, Qin X, Li B, Han Y
Journal of cellular and molecular medicine 2021 Aug;25(15):7545-7558
Journal of cellular and molecular medicine 2021 Aug;25(15):7545-7558
NOD2 inhibits tumorigenesis and increases chemosensitivity of hepatocellular carcinoma by targeting AMPK pathway.
Ma X, Qiu Y, Sun Y, Zhu L, Zhao Y, Li T, Lin Y, Ma D, Qin Z, Sun C, Han L
Cell death & disease 2020 Mar 6;11(3):174
Cell death & disease 2020 Mar 6;11(3):174
Effects of peptidoglycan on the development of steatohepatitis.
Jin M, Lai Y, Zhao P, Shen Q, Su W, Yin Y, Zhang W
Biochimica et biophysica acta. Molecular and cell biology of lipids 2020 Apr;1865(4):158595
Biochimica et biophysica acta. Molecular and cell biology of lipids 2020 Apr;1865(4):158595
The expression of NOD2, NLRP3 and NLRC5 and renal injury in anti-neutrophil cytoplasmic antibody-associated vasculitis.
Wang LY, Sun XJ, Chen M, Zhao MH
Journal of translational medicine 2019 Jun 11;17(1):197
Journal of translational medicine 2019 Jun 11;17(1):197
The synergistic effect of NOD2 and TLR4 on the activation of autophagy in human submandibular gland inflammation.
Li J, Li B, Cheng Y, Meng Q, Wei L, Li W, Zhang J, Huang S
Journal of oral pathology & medicine : official publication of the International Association of Oral Pathologists and the American Academy of Oral Pathology 2019 Jan;48(1):87-95
Journal of oral pathology & medicine : official publication of the International Association of Oral Pathologists and the American Academy of Oral Pathology 2019 Jan;48(1):87-95
NOD2 promotes dopaminergic degeneration regulated by NADPH oxidase 2 in 6-hydroxydopamine model of Parkinson's disease.
Cheng L, Chen L, Wei X, Wang Y, Ren Z, Zeng S, Zhang X, Wen H, Gao C, Liu H
Journal of neuroinflammation 2018 Aug 29;15(1):243
Journal of neuroinflammation 2018 Aug 29;15(1):243
NOD2-RIP2 contributes to the inflammatory responses of mice in vivo to Streptococcus pneumoniae.
Zheng Y, Shang F, An L, Zhao H, Liu X
Neuroscience letters 2018 Apr 3;671:43-49
Neuroscience letters 2018 Apr 3;671:43-49
NOD2 promotes endothelial-to-mesenchymal transition of glomerular endothelial cells via MEK/ERK signaling pathway in diabetic nephropathy.
Shang J, Zhang Y, Jiang Y, Li Z, Duan Y, Wang L, Xiao J, Zhao Z
Biochemical and biophysical research communications 2017 Mar 4;484(2):435-441
Biochemical and biophysical research communications 2017 Mar 4;484(2):435-441
17β-Estradiol and progesterone decrease MDP induced NOD2 expression in bovine mammary epithelial cells.
Xu DD, Wang G, He XJ, Wang JF, Yang B, Sun ZP, Sun DB, He QY, Zhang X, Wu R
Veterinary immunology and immunopathology 2017 Jun;188:59-64
Veterinary immunology and immunopathology 2017 Jun;188:59-64
Progranulin protects against renal ischemia/reperfusion injury in mice.
Zhou M, Tang W, Fu Y, Xu X, Wang Z, Lu Y, Liu F, Yang X, Wei X, Zhang Y, Liu J, Geng X, Zhang C, Wan Q, Li N, Yi F
Kidney international 2015 May;87(5):918-29
Kidney international 2015 May;87(5):918-29
Identification of NOD2 as a novel target of RNA-binding protein HuR: evidence from NADPH oxidase-mediated HuR signaling in diabetic nephropathy.
Shang J, Wan Q, Wang X, Duan Y, Wang Z, Wei X, Zhang Y, Wang H, Wang R, Yi F
Free radical biology & medicine 2015 Feb;79:217-27
Free radical biology & medicine 2015 Feb;79:217-27
NOD2 deficiency protects against cardiac remodeling after myocardial infarction in mice.
Li X, Li F, Chu Y, Wang X, Zhang H, Hu Y, Zhang Y, Wang Z, Wei X, Jian W, Zhang X, Yi F
Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 2013;32(6):1857-66
Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 2013;32(6):1857-66
Novel role of NOD2 in mediating Ca2+ signaling: evidence from NOD2-regulated podocyte TRPC6 channels in hyperhomocysteinemia.
Han H, Wang Y, Li X, Wang PA, Wei X, Liang W, Ding G, Yu X, Bao C, Zhang Y, Wang Z, Yi F
Hypertension (Dallas, Tex. : 1979) 2013 Sep;62(3):506-11
Hypertension (Dallas, Tex. : 1979) 2013 Sep;62(3):506-11
NOD2 promotes renal injury by exacerbating inflammation and podocyte insulin resistance in diabetic nephropathy.
Du P, Fan B, Han H, Zhen J, Shang J, Wang X, Li X, Shi W, Tang W, Bao C, Wang Z, Zhang Y, Zhang B, Wei X, Yi F
Kidney international 2013 Aug;84(2):265-76
Kidney international 2013 Aug;84(2):265-76
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Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- The NOD2 antibody from Proteintech is a rabbit polyclonal antibody to a peptide of human NOD2. This antibody recognizes human, mouse antigen. The NOD2 antibody has been validated for the following applications: ELISA, WB analysis.
