Explore
Validate
Learn
Western blot
ELISAAntibody data
- Antibody Data
- Antigen structure
- References [573]
- Comments [0]
- Validations
- Western blot [1]
- Immunoprecipitation [1]
- Immunohistochemistry [1]
Submit
Validation data
Reference
Comment
Report error
- Product number
- 12186-1-AP - Provider product page
- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#12186-1-AP, RRID:AB_2266320
- Product name
- MFN2 antibody
- Antibody type
- Polyclonal
- Description
- KD/KO validated MFN2 antibody (Cat. #12186-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse, rat and has been validated for the following applications: IHC, IP, WB,ELISA.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references Curcumin augments mitophagy via Nrf2-PINK1-mediated, Parkin-dependent ubiquitination to suppress ferroptosis in post-cardiac arrest brain injury.
The purinergic receptor P2rx7 mediated ATP sensing is required to prevent bone aging by directing mitochondrial fitness of MSCs.
Targeting NME3 to Restore Mitochondrial Fission-Fusion Balance Defines a Novel Disease-Modifying Strategy for Parkinson's Disease.
ACADVL upregulation is associated with placental ferroptosis in intrahepatic cholestasis of pregnancy.
Complement 5a receptor 2 attenuates diabetic kidney disease by promoting mitochondria-associated endoplasmic reticulum membrane formation mediated by PSS-MFN2 interaction.
Mitofusin-2 suppresses tumor immune escape through EGFR/STAT3-mediated PD-L1 transcription.
Dendrobium officinale polysaccharides alleviate atopic dermatitis in vivo and in vitro through inhibition of inflammation and mitochondrial dysfunction.
Cannabidiol attenuates the LPS/D-Galactosamine-induced acute liver injury by inhibiting parkin-mediated ubiquitination of MFN2.
PCSK9 Inhibitor Alirocumab Improves Diabetic Cardiomyopathy Through the ERK/p38 MAPK Signaling Pathway.
Aerobic exercise improve physical endurance and muscle function by ameliorating oxidative stress and modulating mitochondrial dynamics in aged skeletal muscle.
Electroacupuncture mitigates oxidative stress and neuroinflammation in Parkinson's disease via mitigating autophagy-lysosome dysfunction.
Intermittent fasting attenuates ovarian chronic inflammation in obese mice by inhibiting the CXCL12-CXCR4 axis.
Sennoside A alleviates HFD-induced MAFLD by protecting intestinal barrier function through TLR4/NF-κB and mitochondrial quality control.
Echinacoside improves antioxidant responses and angiogenesis through Parkin-MFN2-mediated mitophagy to promote diabetic wound healing.
Caveolin-1 deficiency exacerbates liver fibrosis by driving lipid metabolic reprogramming in hepatic stellate cells via DRP1-mediated mitochondrial fission.
Overexpression of mitofusin 2 ameliorates inflammation and oxidative stress in lipopolysaccharide-induced mastitis model by regulating phosphofurin acidic cluster sorting protein 2.
The Neuroprotective Role of Ginsenoside Rg1 Against Cerebral Ischemia-Reperfusion Damage Through Inhibition of Mitophagy via Blocking Mitophagosome-Lysosome Fusion.
High‑intensity exercise training inhibits excessive autophagy in the hyperlipidemic myocardium of ApoE(‑/‑) mice via the NAD(+)‑mediated SIRT1/MFN2 pathway.
Down-regulation of lipocalin-2 alleviates depressive-like behaviors in mice through modulation of microglial activation.
Lobetyolin alleviates microglial inflammation by activating CK2α/Opa1-mediated mitochondrial fusion in ischemic stroke.
Macelignan, a lignan from Myristica fragrans Houtt., rescues mitochondrial homeostasis and prevents cognitive decline in vascular dementia by modulating the mTOR-Mitophagy axis.
Endoplasmic Reticulum Stress Induced by Turbulence of Mitochondrial Fusion and Fission Was Involved in Isoproterenol-Induced H9c2 Cell Injury.
Molecular mechanism of berberine in ameliorating leptin resistance and mitochondrial dysfunction through the TRIB1-C/EBPα axis in obesity.
BAP31 Modulates Mitochondrial Homeostasis Through PINK1/Parkin Pathway in MPTP Parkinsonism Mouse Models.
ER stress disrupts MFN2-related mitophagy via HRD1-PINK1/ parkin axis in bovine embryos.
The UBC/SIRT5/DRP1 axis regulates mitochondrial dynamics to alleviate Staphylococcus aureus-induced oxidative stress and senescence in bovine mammary epithelial cells.
Mesenchymal Stem Cell-derived Exosomes Alleviate Oxidative Stress and Brain Injuries Through Promoting OPA1 Mediated Mitochondrial Fusion After Intracerebral Hemorrhage.
AMPK Deficiency Induces Corneal Epithelial Barrier Dysfunction by Modulating Energy Homeostasis.
The HEAT repeat protein MROH7 regulates the inflammatory macrophage response via LBP acetylation.
Redox switch C674 in SERCA2 triggers Ca(2+)-calcineurin-MCU-Drp1 cascade and pulmonary vascular remodeling.
Trimethylamine-N-oxide disrupts spermatogenesis by inducing mitochondrial oxidative stress injury through Hippo signaling.
Fibrotic scar formation after cerebral ischemic stroke: Targeting the Sonic hedgehog signaling pathway for scar reduction.
A coenzyme-based "interface-welding" hydrogel coating for titanium implants promotes diabetic osseointegration by regulating mitochondrial dynamics.
Hippocampal HDAC7 induces perioperative neurocognitive disorders via an NF-κB-MFN2-ACSL4 ferroptosis pathway.
Mitochondrial TRPV1 exacerbates cognitive deficits in sepsis-associated encephalopathy by driving microglial metabolic reprogramming.
The integrated stress response suppresses PINK1-dependent mitophagy by preserving mitochondrial import efficiency.
Florfenicol impairs steroid hormone secretion in bovine ovarian granulosa cells: Involvement of the cAMP/PKA/StAR signaling pathway and oxidative stress.
Pestiviruses utilize pyrimidine metabolism to regulate mitophagy for viral replication.
Metformin Alleviates Liver Metabolic Dysfunction in Polycystic Ovary Syndrome by Activating the Ethe1/Keap1/PINK1 Pathway.
Astragaloside IV Alleviates H(2)O(2)-Induced Mitochondrial Dysfunction and Inhibits Mitophagy Via PI3K/AKT/mTOR Pathway.
Augmenter of Liver Regeneration Crotonylation Assists in Mitochondria-ER Contact to Alleviate Hepatic Steatosis.
Metformin Activation of Sirtuin 3 Signaling Regulates Mitochondrial Function Improves Diabetes-Associated Cognitive Impairment.
Silencing ATF3 mediates mitochondrial homeostasis and improves ischemic stroke through regulating the MAPK signaling pathway.
MFN2-a multifaceted guardian against Parkinson's pathophysiology: mitochondria, ferroptosis, inflammation and oxidative stress.
Optineurin overexpression ameliorates neurodegeneration through regulating neuroinflammation and mitochondrial quality in a murine model of amyotrophic lateral sclerosis.
Bavachin suppresses proliferation of laryngopharyngeal cancer by regulating the STAT3 and MAPK signaling pathways.
Mitochondrial dysfunction is a hallmark of woody breast myopathy in broiler chickens.
Calcium dysregulation disrupts mitochondrial homeostasis by interfering AMPK/Drp1 pathway to aggravate plaque progression and instability.
Vine-inspired zinc-ion modified black phosphorus coating accelerates bone tissue infiltration of 3D printed scaffolds.
Human milk-derived 5'-UMP promotes thermogenesis and mitochondrial biogenesis to ameliorate obesity.
Cardioprotective effect of Yiqi Huoxue decoction on post-myocardial infarction injury mediated by Ca(2+) flux through MAMs.
Discovery of a novel chalcone-derived covalent Keap1 binder for mitigating cisplatin-induced mitochondrial dysfunction and nephrotoxicity.
miR-223-3p Mitigates Mitochondrial Dysfunction and Cementoblast Apoptosis in Orthodontic Root Resorption via FoxO3.
Chimeric deubiquitinase engineering reveals structural basis for specific inhibition of the mitophagy regulator USP30.
Gut microbiota regulation by Lactiplantibacillus plantarum SG5 enhances mitochondrial function in Parkinson's disease mice via the GLP-1/PGC-1α pathway.
Modulating Macrophage-Nucleus Pulposus Cell Crosstalk via Sequential Drug Delivery Attenuates Disc Degeneration.
Mechanism of mitofusin 2, mitochondria-associated membrane, and the mitochondrial pathway in alleviating oxidative stress and cell senescence in bovine mammary epithelial cells.
ARIH1 Promotes Preeclampsia by Inducing MFN2-Dependent Hypoxia-Triggered Mitophagy and Endoplasmic Reticulum Stress in Trophoblasts.
Mechanism of Piezo1 regulating chondrocyte mitochondrial function and promoting fracture healing through β-catenin/LARS2 signaling pathway.
Copper-mediated MAM regulation of the NF-κB signalling pathway enhances Seneca Valley virus replication in PK-15 cells.
Electroacupuncture Regulates Mitochondria-Endoplasmic Reticulum interactions via Fn1 in a Parkinson's Disease Model: Transcriptomic Evidence.
Gestational zearalenone causes fetal intrauterine growth restriction partially through deriving ROS-Drp1 mediated placental PANoptosis.
Parkin modulates the hepatocellular carcinoma microenvironment by regulating PD-1/PD-L1 signalling.
Porcine GWAS identifies ACOT11 as regulator for macrophage IL-1β maturation via IFNGR2 palmitoylation.
PGC-1α Expands Neural Precursor Pool and Facilitates Cognitive Recovery Within AD Hippocampus Through the Regulation of Mitochondrial Dynamics.
Skeletal Muscle PGC-1α Remodels Mitochondrial Phospholipidome but Does Not Alter Energy Efficiency for ATP Synthesis.
IRE1α translational suppression potentiates STING-dependent chemoresistance in pancreatic cancer.
MTCH2 modulates CPT1 activity to regulate lipid metabolism of adipocytes.
Luteoloside alleviates bleomycin-induced pulmonary fibrosis in mice via SIRT1-mediated protective effect against alveolar epithelial cell senescence.
FGF21-FGFR1 signaling protects against cardiac hypertrophy by regulating PINK1-mediated mitophagy pathway.
Mesenchymal stem cells inhibit mitochondrial fission by upregulating armadillo repeat containing 1, ameliorating oxidative stress in renal fibrosis.
MAM-Mediated Mitochondrial Ca(2+) Overload and Endoplasmic Reticulum Stress Aggravates Synaptic Plasticity Impairment in Diabetic Mice.
Atrazine-induced hippocampal neurotoxicity: Involvement of Drp1-mediated mitochondrial fission.
PTEN-L dephosphorylates Parkin and Ub Ser65 to aggravate mitophagy dysfunction in prion disease cell models.
SAP30BP aggravates mitochondrial-related ferroptosis in diabetic cardiomyopathy by regulating MFN2-ACSL4 axis.
Role of neuroglia cell-derived microvesicles in cobalt chloride-induced mitochondrial autophagy in neurons.
Targeting STING alleviates pyroptosis of bladder epithelial cells and ameliorates bladder fibrosis in neurogenic bladder.
Electroacupuncture improves motor function after ischemic stroke via regulating mitochondrial dynamics.
Baicalin alleviates oxidative stress in DF-1 cell line via the Mfn2/MAMs/Ca (2+) pathway.
Mfn2 Regulates Scleral Remodeling in Myopia by Maintaining Endoplasmic Reticulum Homeostasis in Scleral Fibroblasts.
Oxymatrine Alleviates Cerebral Ischemia/Reperfusion Injury By Targeting HDAC1 to Regulate Mitochondria-Related Autophagy and Oxidative Stress.
CCDC141 is a Connectin/Titin and Nesprin-1 binding protein that adapts cardiomyocytes to mechanical stress.
TAAR1 deficiency impairs mitochondrial dynamics and synaptic integrity in the medial prefrontal cortex and associated cognition in mice.
Renal clearable CRISPR nanosensor targeting mitochondrial DNA mutation for noninvasive monitoring of tumor progression and metastasis.
Nrf2 alleviates excessive deposition of extracellular matrix in mammary fibrosis through TGF/Smad and ROS signals.
Cisplatin transported by COX17 induces cochlear damage by binding Myosin IIA to regulate cell pyroptosis induced by mitochondrial dysfunction.
OAC1 improves mitofusin 2 expression to alleviate neuronal injury following experimental ischemic stroke.
Effect of disruption of mitochondrial and endoplasmic reticulum calcium homeostasis on neurites in hydrogen peroxide- and ionomycin-treated cells.
Ginsenoside Rg5 alleviates radiation-induced acute lung vascular endothelium injury by reducing mitochondrial apoptosis via Sirt1.
Protective effect of astragaloside IV against zinc oxide nanoparticles induced human neuroblastoma SH-SY5Y cell death: a focus on mitochondrial quality control.
Cardioprotective effects of Dendrobium officinale polysaccharides on thiacloprid-induced cardiac injury via modulating mitochondrial dynamics.
FTO-mediated m6A modification elevates the MFN2 mRNA stability to suppress ovarian granulosa cell senescence.
SIRT5 modulates mitochondria function via mitophagy and antioxidant mechanisms to facilitate oocyte maturation in mice.
Empagliflozin attenuates renal damage in diabetic nephropathy by modulating mitochondrial quality control via Prdx3-PINK1 pathway.
Salidroside alleviates doxorubicin-induced hepatotoxicity via Sestrin2/AMPK-mediated pyroptotic inhibition.
Lycium barbarum glycopeptide attenuates intracerebral hemorrhage-induced inflammation and oxidative stress via activation of the Sirt3 signaling pathway.
Mechanistic study of modulating mitochondrial fission and fusion to ameliorate neuropathic pain in mice.
Overexpression of c-Myc triggers p62 aggregation-mediated mitochondrial mitophagy in cabozantinib resistance of hepatocellular carcinoma.
Mitochondrial aldehyde dehydrogenase restores the migratory capacity inhibited by high glucose-induced hyperosmolality.
Cardiomyocyte specific CD38 deletion protects heart from acute myocardial infarction by activating Sirt3 signaling pathway.
Leucine 7 is a key residue for mutant huntingtin-induced mitochondrial pathology and neurotoxicity in Huntington's disease.
Procyanidin B2 alleviates damage to mouse testicular tissue after freezing by inhibiting oxidative stress and apoptosis.
Impact of POU3F4 mutation on cochlear development and auditory function.
S-nitrosylation of peroxiredoxin 2 exacerbates hyperuricemia-induced renal injury through regulation of mitochondrial homeostasis.
Neurotoxicity of Realgar: Crosstalk Between UBXD8-DRP1-Regulated Mitochondrial Fission and PINK1-Parkin-Mediated Mitophagy.
Piwei Peiyuan Prescription Attenuates the Progression of Chronic Atrophic Gastritis by Eliciting MAPK10-Mediated Mitochondrial Autophagy.
Autophagy receptor optineurin promotes spring viremia of carp virus replication via mitophagy and innate immune pathways in Cyprinus carpio.
Lycium barbarum polysaccharide alleviate cadmium-induced mitochondrial dysfunction mediated pyroptosis in duck liver.
Triptolide inhibits migration and viability, and promotes apoptosis by targeting the PI3K/Akt signaling pathway via upregulation of miR‑125a‑5p in SW1353 human chondrosarcoma cells.
Salmonella Typhimurium persistently infects host via its effector SseJ-induced PHB2-mediated mitophagy.
Astragaloside IV Relieves Mitochondrial Oxidative Stress Damage and Dysfunction in Diabetic Mice Endothelial Progenitor Cells by Regulating the GSK-3β/Nrf2 Axis.
Schisandrin B regulates mitochondrial dynamics via AKT1 activation and mitochondrial targeting to ameliorate renal ischemia-reperfusion injury.
Injectable pH Responsive Conductive Hydrogel for Intelligent Delivery of Metformin and Exosomes to Enhance Cardiac Repair after Myocardial Ischemia-Reperfusion Injury.
Diallyl Trisulfide From Garlic Regulates RAB18 Phase Separation to Inhibit Lipophagy and Induce Cuproptosis in Hepatic Stellate Cells for Antifibrotic Effects.
Intratracheal Administration of Polystyrene Micro(nano)plastics with a Mixed Particle Size Promote Pulmonary Fibrosis in Rats by Activating TGF-β1 Signaling and Destabilizing Mitochondrial Dynamics and Mitophagy in a Dose- and Time-Dependent Manner.
PINK1 affects mitochondrial oxidative phosphorylation by regulating MFN2 to alleviate diabetic kidney disease.
STING-mediated mitochondrial DNA release exacerbates PANoptosis in liver ischemia reperfusion injury.
O-GlcNAcylation-mediated endothelial metabolic memory contributes to cardiac damage via small extracellular vesicles.
Reduced NRF2/Mfn2 activity promotes endoplasmic reticulum stress and senescence in adipose-derived mesenchymal stem cells in hypertrophic obese mice.
Ginsenoside Rh2 Exerts a Therapeutic Effect against Myocardial Infarction via Promoting Angiogenesis and Mitochondrial Bioenergetics.
Acetaldehyde dehydrogenase 2 attenuates lipopolysaccharide -induced endothelial barrier damage by inhibiting mitochondrial fission in sepsis-associated encephalopathy.
Endosomal RFFL ubiquitin ligase regulates mitochondrial morphology by targeting mitofusin 2.
Bavachin ameliorates cisplatin-induced nephrotoxicity by enhancing mitochondrial β-oxidation and lipid metabolism through MFN2.
The role of mitochondrial dysfunction in the protective effect of ginger derived extracellular vesicles on hepatic stellate cells against cytotoxicity.
Norepinephrine Attenuates Benzalkonium Chloride-Induced Dry Eye Disease by Regulating the PINK1/Parkin Mitophagy Pathway.
Downregulation of Mfn2 Contributes to Chronic Postsurgical Pain via Inducing the Pyroptosis of GABAergic Neurons in the Spinal Cord.
Extremely low-frequency electromagnetic field (ELF-EMF) enhances mitochondrial energy production in NARP cybrids.
Increased ROS levels activate AMPK-ULK1-mediated mitophagy to promote pseudorabies virus replication.
S-COS-Se mitigates cadmium-induced oxidative stress, inflammation, and immunotoxicity by restoring immune balance and inhibiting mitochondria-pyroptosis crosstalk.
Tang Bi formula alleviates diabetic sciatic neuropathy via AMPK/PGC-1α/MFN2 pathway activation.
Drp1-Dependent Mitochondrial Fission Contributes to Lactic Acid-Induced Chicken Cardiomyocyte Damage.
SENP1 prevents high fat diet-induced non-alcoholic fatty liver diseases by regulating mitochondrial dynamics.
Hydrogen restores central tryptophan and metabolite levels and maintains mitochondrial homeostasis to protect rats from chronic mild unpredictable stress damage.
9-PAHSA ameliorates microvascular damage during cardiac ischaemia/reperfusion injury by promoting LKB1/AMPK/ULK1-mediated autophagy-dependent STING degradation.
TNFα-reliant FSP1 up-regulation promotes intervertebral disc degeneration via caspase 3-dependent apoptosis.
Rostellularia procumbens (L) Nees. extract attenuates adriamycin-induced nephropathy by maintaining mitochondrial dynamics balance via SIRT1/PGC-1α signaling pathway activation.
Rg1 improves Alzheimer's disease by regulating mitochondrial dynamics mediated by the AMPK/Drp1 signaling pathway.
Po-Ge-Jiu-Xin decoction alleviate sepsis-induced cardiomyopathy via regulating phosphatase and tensin homolog-induced putative kinase 1 /parkin-mediated mitophagy.
Study on the role of Dihuang Yinzi in regulating the AMPK/SIRT1/PGC-1α pathway to promote mitochondrial biogenesis and improve Alzheimer's disease.
Dapagliflozin and Sirtuin-1 interaction and mechanism for ameliorating atrial fibrillation in a streptozotocin-induced rodent diabetic model.
Isovitexin targets SIRT3 to prevent steroid-induced osteonecrosis of the femoral head by modulating mitophagy-mediated ferroptosis.
Engineered hypoxia-responsive albumin nanoparticles mediating mitophagy regulation for cancer therapy.
Ginsenoside Rb3 Promotes Opa1-Mediated Regenerative Neurogenesis via Activating the Ido1 Pathway in Ischemic Stroke.
Role of MFN2 in bovine embryonic development and the mitigation of ER stress.
Chronic alcohol consumption exacerbates ischemia-associated skeletal muscle mitochondrial dysfunction in a murine model of peripheral artery disease.
HIV-1 gp120 Interactions with Nicotine Modulate Mitochondrial Network Properties and Amyloid Release in Microglia.
Nrf2 activator tertiary butylhydroquinone enhances neural stem cell differentiation and implantation in Alzheimer's disease by boosting mitochondrial function.
Dexmedetomidine ameliorates hepatic ischemia reperfusion injury via modulating SIRT3 mediated mitochondrial quality control.
Buyang Huanwu Decoction restores the balance of mitochondrial dynamics after cerebral ischemia-reperfusion through calcium overload reduction by the PKCε-Nampt-Sirt5 axis.
PANAXADIOL SAPONIN ALLEVIATES LPS-INDUCED CARDIOMYOPATHY SIMILAR TO DEXAMETHASONE VIA IMPROVING MITOCHONDRIAL QUALITY CONTROL.
C3a/C3aR axis is involved in diabetic kidney injury by regulating podocyte mitophagy in diabetic nephropathy.
RAB3GAP2 silencing alleviates oxidative stress in cataracts by enhancing Mfn2-mediated mitochondrial autophagy by activating JNK/STAT3.
Cytosolic TOP3α facilitates mitochondrial DNA sensing by cGAS.
ER stress sensor PERK drives ferroptosis by disrupting MAMs-mediated mitochondrial homeostasis and promoting mtROS accumulation in acute myocardial infarction.
ATP1B4 as a candidate upstream regulator of muscle atrophy in diabetic sarcopenia via PI3K/AKT/mTOR-mediated autophagy.
Hispolon reduces mitochondrial dysfunction and improves fibrosis of diabetes nephropathy by activating AMPK signal and inhibiting mPTP opening.
The binding of PCBP2 to IGF2 mRNA restores mitochondrial function in granulosa cells to ameliorate ovarian function in premature ovarian insufficiency mice.
KDM6B induces demethylation of H3K27me3 in MFN1 to modulate aberrant mitophagy in sepsis-induced acute lung injury.
Multi-Omics Analysis Reveals Distinct Lipid Remodelling and Mitochondrial Stress in SH-SY5Y Cells Modelling Parkinson's Disease.
Gpr109a alleviates mammary fibrosis via PPARγ-mediated reduction of ROS and mitochondrial damage.
Schwann cell Lrp1 deletion drives trigeminal neuron sensitization and orofacial pain by modulating mitochondrial function and TRPV1/TRPA1 activity.
NDUFAB1 promotes hepatocellular carcinoma progression by disrupting mitochondrial homeostasis and mitophagy pathway.
FUNDC1-dependent mitochondrial-ER membranes mediate mitochondrial dysfunction and melanocyte damage under oxidative stress.
Leber's hereditary optic neuropathy-associated ND1 3733G>C mutation ameliorates the mitochondrial quality control and cellular homeostasis.
The low-density lipoprotein receptor-related protein-1 (LRP1) in Schwann cells controls mitochondria homeostasis in peripheral nerves.
Mn(2)O(3) NPs-induced liver injury is potentially associated with gut microbiota dysbiosis in broiler chicken.
Decoding the role of nucleic acid binding protein 2 in lipid dysregulation and hepatocellular carcinoma progression through LKB1-mediated mitochondrial dysfunction.
Melatonin mitigates arsenic and fluoride-induced cardiotoxicity in chickens by maintaining mitochondrial homeostasis.
Umbilical Cord Mesenchymal Stem Cell-Derived Extracellular Vesicles Enhance Chondrocyte Function by Reducing Oxidative Stress in Chondrocytes.
Targeting Wnt/beta-catenin signaling to attenuate short-chain chlorinated paraffins-triggered hepatocyte mitochondrial fission and subsequent pyroptosis.
SIRT1 and its SUMOylation attenuate hyperoxia-induced lung injury by improving mitochondrial biogenesis and fusion.
PGAM5 aggravated doxorubicin-induced cardiotoxicity by disturbing mitochondrial dynamics and exacerbating cardiomyocytes apoptosis.
O-GlcNAcylation of hexokinase 2 modulates mitochondrial dynamics and enhances the progression of lung cancer.
Dietary salt promotes cognitive impairment through repression of SIRT3/PINK1-mediated mitophagy and fission.
Schisandrin B Improves Mitochondrial Function and Inhibits HT22 Cell Apoptosis by Regulating Sirt3 Protein.
Long term exposure to multiple environmental stressors induces mitochondrial dynamics imbalance in testis: Insights from metabolomics and transcriptomics.
Inhibition of USP30 Promotes Mitophagy by Regulating Ubiquitination of MFN2 by Parkin to Attenuate Early Brain Injury After SAH.
Evolocumab attenuates myocardial ischemia/reperfusion injury by blocking PCSK9/LIAS-mediated cuproptosis of cardiomyocytes.
Epimedii Folium and Ligustri Lucidi Fructus synergistically delay renal aging through AMPK/ULK1/Bcl2L13-mediated mitophagy.
Mitofusin-Mediated Mitochondrial Fusion Inhibits Pseudorabies Virus Infection in Porcine Cells.
Effect of 1-DNJ on Oxidative Stress-Induced Apoptosis in Porcine Ovarian GCs Through Modulation of the PERK-ATF4/MFN2 Signaling Pathway.
ARMC1 partitions between distinct complexes and assembles MIRO with MTFR to control mitochondrial distribution.
Asparagine transporter supports macrophage inflammation via histone phosphorylation.
PTPLAD1 Regulates PHB-Raf Interaction to Orchestrate Epithelial-Mesenchymal and Mitofusion-Fission Transitions in Colorectal Cancer.
Loss of MTX2 causes mitochondrial dysfunction, podocyte injury, nephrotic proteinuria and glomerulopathy in mice and patients.
Circular RNA TAF4B targeting MFN2 accelerates cell growth in bladder cancer through p27 depression and AKT activation.
Dl-3-n-butylphthalide attenuates cerebral ischemia/reperfusion injury in mice through AMPK-mediated mitochondrial fusion.
FUNDC1 alleviates doxorubicin-induced cardiotoxicity by restoring mitochondrial-endoplasmic reticulum contacts and blocked autophagic flux.
Circular RNA SCMH1 suppresses KMO expression to inhibit mitophagy and promote functional recovery following stroke.
β-arrestin1 protects intestinal tight junction through promoting mitofusin 2 transcription to drive parkin-dependent mitophagy in colitis.
PKD regulates mitophagy to prevent oxidative stress and mitochondrial dysfunction during mouse oocyte maturation.
Targeting translocator protein protects against myocardial ischemia/reperfusion injury by alleviating mitochondrial dysfunction.
The potential benefits of PGC-1α in treating Alzheimer's disease are dependent on the integrity of the LLKYL L3 motif: Effect of regulating mitochondrial axonal transportation.
PDK4-mediated Nrf2 inactivation contributes to oxidative stress and diabetic kidney injury.
Mesenchymal stem cells in tumor microenvironment: drivers of bladder cancer progression through mitochondrial dynamics and energy production.
Helicobacter pylori CagA mediated mitophagy to attenuate the NLRP3 inflammasome activation and enhance the survival of infected cells.
Dysregulation of mitochondrial dynamics and mitophagy are involved in high-fat diet-induced steroidogenesis inhibition.
The tumor suppressor Parkin exerts anticancer effects through regulating mitochondrial GAPDH activity.
Neuronal HIPK2-HDAC3 axis regulates mitochondrial fragmentation to participate in stroke injury and post-stroke anxiety like behavior.
Resveratrol protects against a high-fat diet-induced neuroinflammation by suppressing mitochondrial fission via targeting SIRT1/PGC-1α.
SIRT1 regulates mitochondrial fission to alleviate high altitude hypoxia inducedcardiac dysfunction in rats via the PGC-1α-DRP1/FIS1/MFF pathway.
piR112710 attenuates diabetic cardiomyopathy through inhibiting Txnip/NLRP3-mediated pyroptosis in db/db mice.
Qifu-yin activates the Keap1/Nrf2/ARE signaling and ameliorates synaptic injury and oxidative stress in APP/PS1 mice.
Supplementation of Chlorogenic Acid Alleviates the Effects of H(2)O(2)-Induced Oxidative Stress on Laying Performance, Egg Quality, Antioxidant Capacity, Hepatic Inflammation, Mitochondrial Dysfunction, and Lipid Accumulation in Laying Hens.
SETDB1 targeting SESN2 regulates mitochondrial damage and oxidative stress in renal ischemia-reperfusion injury.
Pseudorabies virus infection triggers mitophagy to dampen the interferon response and promote viral replication.
Apoptosis, Mitochondrial Autophagy, Fission, and Fusion Maintain Mitochondrial Homeostasis in Mouse Liver Under Tail Suspension Conditions.
Dapagliflozin alleviates right heart failure by promoting collagen degradation by reducing ROS levels.
Copper induced cytosolic escape of mitochondrial DNA and activation of cGAS-STING-NLRP3 pathway-dependent pyroptosis in C8-D1A cells.
Characterization of fission and fusion mitochondrial dynamics in HD fibroblasts according to patient's severity status.
Yiqihuoxue decoction (GSC) inhibits mitochondrial fission through the AMPK pathway to ameliorate EPCs senescence and optimize vascular aging transplantation regimens.
SGLT2 inhibitor canagliflozin reduces visceral adipose tissue in db/db mice by modulating AMPK/KLF4 signaling and regulating mitochondrial dynamics to induce browning.
Readdressing the Localization of Apolipoprotein E (APOE) in Mitochondria-Associated Endoplasmic Reticulum (ER) Membranes (MAMs): An Investigation of the Hepatic Protein-Protein Interactions of APOE with the Mitochondrial Proteins Lon Protease (LONP1), Mitochondrial Import Receptor Subunit TOM40 (TOMM40) and Voltage-Dependent Anion-Selective Channel 1 (VDAC1).
Contribution of impaired autophagy, mitochondrial dysfunction and abnormal lipolysis to epididymal aging in mice.
Isoliquiritigenin alleviates cerebral ischemia-reperfusion injury by reducing oxidative stress and ameliorating mitochondrial dysfunction via activating the Nrf2 pathway.
Diallyl disulfide alleviates hepatic steatosis by the conservative mechanism from fish to tetrapod: Augment Mfn2/Atgl-Mediated lipid droplet-mitochondria coupling.
SIRT1, a target of miR-708-3p, alleviates fluoride-induced neuronal damage via remodeling mitochondrial network dynamics.
Cellular ATP demand creates metabolically distinct subpopulations of mitochondria.
E3 ubiquitin ligase TRIM31 alleviates dopaminergic neurodegeneration by promoting proteasomal degradation of VDAC1 in Parkinson's Disease model.
Hydrogen Protects Mitochondrial Function by Increasing the Expression of PGC-1α and Ameliorating Myocardial Ischaemia-Reperfusion Injury.
Mitochondrial elongation confers protection against doxorubicin-induced cardiotoxicity.
Endothelial Birc3 promotes renal fibrosis through modulating Drp1-mediated mitochondrial fission via MAPK/PI3K/Akt pathway.
Ligustilide alleviates oxidative stress during renal ischemia-reperfusion injury through maintaining Sirt3-dependent mitochondrial homeostasis.
Endo-Lysosomal Network Disorder Reprograms Energy Metabolism in SorL1-Null Rat Hippocampus.
Diacylglycerol O-acyltransferase isoforms play a role in peridroplet mitochondrial fatty acid metabolism in bovine liver.
Psmb8 inhibits mitochondrial fission and alleviates myocardial ischaemia/reperfusion injury by targeting Drp1 degradation.
Therapeutic utility of Perfluorocarbon Oxygent in limiting the severity of subarachnoid hemorrhage in mice.
ACSL1 improves pulmonary fibrosis by reducing mitochondrial damage and activating PINK1/Parkin mediated mitophagy.
Procyanidin C1 ameliorates acidic pH stress induced nucleus pulposus degeneration through SIRT3/FOXO3-mediated mitochondrial dynamics.
Targeting DUSP26 to drive cardiac mitochondrial dynamics via FAK-ERK signaling in diabetic cardiomyopathy.
Schwann cell-secreted frizzled-related protein 1 dictates neuroinflammation and peripheral nerve degeneration after neurotrauma.
Acrolein exposure affects ovarian function by interfering with glycolysis and mitochondrial energy metabolism in mouse.
TRPA1 protects against contrast-induced renal tubular injury by preserving mitochondrial dynamics via the AMPK/DRP1 pathway.
Hydrogen sulfide upregulates SIRT1 to inhibit ox-HDL-induced endothelial cell damage and mitochondrial dysfunction.
Deafness-associated tRNA(Phe) mutation impaired mitochondrial and cellular integrity.
Human neural stem cells promote mitochondrial genesis to alleviate neuronal damage in MPTP-induced cynomolgus monkey models.
Exercise ameliorates muscular excessive mitochondrial fission, insulin resistance and inflammation in diabetic rats via irisin/AMPK activation.
BAG3 localizes to mitochondria in cardiac fibroblasts and regulates mitophagy.
Alpha-ketoglutaric acid attenuates oxidative stress and modulates mitochondrial dynamics and autophagy of spleen in a piglet model of lipopolysaccharide-induced sepsis.
IGF2BP3-stabilized CAMK1 regulates the mitochondrial dynamics of renal tubule to alleviate diabetic nephropathy.
Non-cytopathic bovine viral diarrhea virus (BVDV) inhibits innate immune responses via induction of mitophagy.
Proteomic analysis of mitochondria associated membranes in renal ischemic reperfusion injury.
Differential impact of sex on regulation of skeletal muscle mitochondrial function and protein homeostasis by hypoxia-inducible factor-1α in normoxia.
CGI1746 targets σ(1)R to modulate ferroptosis through mitochondria-associated membranes.
ACSF2 and lysine lactylation contribute to renal tubule injury in diabetes.
Decreasing mitochondrial fission ameliorates HIF-1α-dependent pathological retinal angiogenesis.
Mitofusin 2 plays a critical role in maintaining the functional integrity of the neuromuscular-skeletal axis.
Dietary α-Ketoglutarate Alleviates Escherichia coli LPS-Induced Intestinal Barrier Injury by Modulating the Endoplasmic Reticulum-Mitochondrial System Pathway in Piglets.
Acid Neutralization by Composite Lysine Nanoparticles for Spinal Cord Injury Recovery through Mitigating Mitochondrial Dysfunction.
Targeting the smooth muscle cell KEAP1-Nrf2-STING axis with pterostilbene attenuates abdominal aortic aneurysm.
Zearalenone modulates the function of goat endometrial cells via the mitochondrial quality control system.
Mitofusin2 Ameliorated Endoplasmic Reticulum Stress and Mitochondrial Reactive Oxygen Species Through Maintaining Mitochondria-Associated Endoplasmic Reticulum Membrane Integrity in Cisplatin-Induced Acute Kidney Injury.
Sentrin-specific protease 1 maintains mitochondrial homeostasis through targeting the deSUMOylation of sirtuin-3 to alleviate oxidative damage induced by hepatic ischemia/reperfusion.
Cytoplasmic Escape of Mitochondrial DNA Mediated by Mfn2 Downregulation Promotes Microglial Activation via cGas-Sting Axis in Spinal Cord Injury.
Drp1 regulated PINK1-dependent mitophagy protected duck follicular granulosa cells from acute heat stress injury.
High-fat diet-induced L-saccharopine accumulation inhibits estradiol synthesis and damages oocyte quality by disturbing mitochondrial homeostasis.
Uncovering impaired mitochondrial and lysosomal function in adipose-derived stem cells from obese individuals with altered biological activity.
Dietary xylo-oligosaccharides alleviates LPS-induced intestinal injury via endoplasmic reticulum-mitochondrial system pathway in piglets.
MCT1-governed pyruvate metabolism is essential for antibody class-switch recombination through H3K27 acetylation.
Prenatal hormone stress triggers embryonic cardiac hypertrophy outcome by ubiquitin-dependent degradation of mitochondrial mitofusin 2.
Aluminum-maltol induced oxidative stress and reduced AMPK activity via BCK-related energy supply failure in C6 cell.
Fluorochloridone induces mitochondrial dysfunction and apoptosis in primary goat Sertoli cells.
MicroRNA-129-1-3p protects chicken granulosa cells from cadmium-induced apoptosis by down-regulating the MCU-mediated Ca(2+) signaling pathway.
Intermittent Theta Burst Stimulation Attenuates Cognitive Deficits and Alzheimer's Disease-Type Pathologies via ISCA1-Mediated Mitochondrial Modulation in APP/PS1 Mice.
AGK2 pre-treatment protects against thioacetamide-induced acute liver failure via regulating the MFN2-PERK axis and ferroptosis signaling pathway.
NSD2 modulates Drp1-mediated mitochondrial fission in chronic renal allograft interstitial fibrosis by methylating STAT1.
Blockade of angiotensin II modulates insulin-like growth factor 1-mediated skeletal muscle homeostasis in experimental steatohepatitis.
Photobiomodulation therapy alleviates repeated closed head injury-induced anxiety-like behaviors.
Effects of metformin on glucose metabolism and mitochondrial function in patients with obstructive sleep apnea: A pilot randomized trial.
Coenzyme Q10 Protects Against Hyperlipidemia-Induced Osteoporosis by Improving Mitochondrial Function via Modulating miR-130b-3p/PGC-1α Pathway.
The E3 ubiquitin ligase MARCH2 protects against myocardial ischemia-reperfusion injury through inhibiting pyroptosis via negative regulation of PGAM5/MAVS/NLRP3 axis.
Mitochondria-mediated ferroptosis contributes to the inflammatory responses of bovine viral diarrhea virus (BVDV) in vitro.
Deficient tRNA posttranscription modification dysregulated the mitochondrial quality controls and apoptosis.
Serine synthesis sustains macrophage IL-1β production via NAD(+)-dependent protein acetylation.
Antrodia cinnamomea triterpenoids attenuate cardiac hypertrophy via the SNW1/RXR/ALDH2 axis.
Halofuginone ameliorates the susceptibility to atrial fibrillation by activating the PI3K/Akt signaling pathway.
Particulate matter induced cognitive impairments via endoplasmic reticulum stress-mediated damage to mitochondria-associated endoplasmic reticulum membranes in immature rats.
Sirt3-Mediated Opa1 Deacetylation Protects Against Sepsis-Induced Acute Lung Injury by Inhibiting Alveolar Macrophage Pro-Inflammatory Polarization.
Regulatory roles of histamine receptor in astrocytic glutamate clearance under conditions of increased glucose variability.
New TIPARP inhibitor rescues mitochondrial function and brain injury in ischemic stroke.
Oleanonic acid ameliorates mutant Aβ precursor protein-induced oxidative stress, autophagy deficits, ferroptosis, mitochondrial damage, and ER stress in vitro.
Activated DRP1 promotes mitochondrial fission and induces glycolysis in ATII cells under hyperoxia.
SUCNR 1 promotes atherosclerosis by inducing endoplasmic reticulum stress mediated ER-mito crosstalk.
High concentration hydrogen attenuates sepsis-induced acute kidney injury by promoting mitochondrial biogenesis and fusion.
Aflatoxin B1 Promotes Pyroptosis in IPEC-J2 Cells by Disrupting Mitochondrial Dynamics through the AMPK/NLRP3 Pathway.
Myricetin Alleviates Silica-Mediated Lung Fibrosis via PPARγ-PGC-1α Loop and Suppressing Mitochondrial Senescence in Epithelial Cells.
Disturbance of mitochondrial dynamics led to spermatogenesis disorder in mice exposed to polystyrene micro- and nanoplastics.
Impaired mitochondrial quality control in fibromyalgia: Mechanisms involved in skeletal muscle alteration.
Activating MC4R Promotes Functional Recovery by Repressing Oxidative Stress-Mediated AIM2 Activation Post-spinal Cord Injury.
Repeated Ketamine Anesthesia during the Neonatal Period Impairs Hippocampal Neurogenesis and Long-Term Neurocognitive Function by Inhibiting Mfn2-Mediated Mitochondrial Fusion in Neural Stem Cells.
Presenilin2 D439A Mutation Induces Dysfunction of Mitochondrial Fusion/Fission Dynamics and Abnormal Regulation of GTPase Activity.
Icariin Ameliorates D-galactose-induced Cell Injury in Neuron-like PC12 Cells by Inhibiting MPTP Opening.
MicroRNA-15b promotes cardiac ischemia injury by the inhibition of Mitofusin 2/PERK pathway.
Aldehyde Dehydrogenase 2 Deficiency Aggravates Lung Fibrosis through Mitochondrial Dysfunction and Aging in Fibroblasts.
The effects of the atrial natriuretic peptide deficiency on renal cortical mitochondrial bioenergetics in the Dahl SS rat.
Tetramerization of PKM2 Alleviates Traumatic Brain Injury by Ameliorating Mitochondrial Damage in Microglia.
Mannan-binding lectin inhibits oxidative stress-induced senescence via the NAD+/Sirt1 pathway.
The mechanism of extracellular CypB promotes glioblastoma adaptation to glutamine deprivation microenvironment.
VDR regulates mitochondrial function as a protective mechanism against renal tubular cell injury in diabetic rats.
Disturbance of mitochondrial dynamics in myocardium of broilers with pulmonary hypertension syndrome.
DsbA-L ameliorates renal aging and renal fibrosis by maintaining mitochondrial homeostasis.
Astragaloside IV combined with ligustrazine ameliorates abnormal mitochondrial dynamics via Drp1 SUMO/deSUMOylation in cerebral ischemia-reperfusion injury.
Mitochondria-associated endoplasmic reticulum membranes tethering protein VAPB-PTPIP51 protects against ischemic stroke through inhibiting the activation of autophagy.
Schisandrin B Alleviates LPS Induced Mitochondrial Damage in C28I2 Cells.
Excessive processing and acetylation of OPA1 aggravate age-related hearing loss via the dysregulation of mitochondrial dynamics.
The NLRX1-SLC39A7 complex orchestrates mitochondrial dynamics and mitophagy to rejuvenate intervertebral disc by modulating mitochondrial Zn(2+) trafficking.
Moderate replacement of fish oil with palmitic acid-stimulated mitochondrial fusion promotes β-oxidation by Mfn2 interacting with Cpt1α via its GTPase-domain.
Fufang Luohanguo Qingfei granules reduces influenza virus susceptibility via MAVS-dependent type I interferon antiviral signaling.
Phosphoglycerate mutase 5 exacerbates liver ischemia-reperfusion injury by activating mitochondrial fission.
Icaritin with autophagy/mitophagy inhibitors synergistically enhances anticancer efficacy and apoptotic effects through PINK1/Parkin-mediated mitophagy in hepatocellular carcinoma.
LonP1 Links Mitochondria-ER Interaction to Regulate Heart Function.
Electroacupuncture Ameliorates Depression-Like Behaviors in Post-Stroke Rats via Activating AMPK-Mediated Mitochondrial Function.
ShenQiWan ameliorates renal injury in type 2 diabetic mice by modulating mitochondrial fusion and endoplasmic reticulum stress.
Growth hormone remodels the 3D-structure of the mitochondria of inflammatory macrophages and promotes metabolic reprogramming.
Blockage of S100A8/A9 ameliorates septic nephropathy in mice.
Exercise intervention improves mitochondrial quality in non-alcoholic fatty liver disease zebrafish.
Investigating the effect of dehydromiltirone on septic AKI using a network pharmacology method, molecular docking, and experimental validation.
Menaquinone-4 prevents medication-related osteonecrosis of the jaw through the SIRT1 signaling-mediated inhibition of cellular metabolic stresses-induced osteoblast apoptosis.
Aerobic exercise enhances mitochondrial homeostasis to counteract D-galactose-induced sarcopenia in zebrafish.
Loss and recovery of myocardial mitochondria in mice under different tail suspension time: Apoptosis and mitochondrial fission, fusion and autophagy.
UBQLN2 and HSP70 participate in Parkin-mediated mitophagy by facilitating outer mitochondrial membrane rupture.
Mitophagy disorder mediates cardiac deterioration induced by severe hypoglycemia in diabetic mice.
Mitochondrial miR-12294-5p regulated copper-induced mitochondrial oxidative stress and mitochondrial quality control imbalance by targeted inhibition of CISD1 in chicken livers.
Nuclear erythroid 2-related factor 2 protects against reactive oxygen species -induced preterm premature rupture of membranes through regulation of mitochondria†.
DMT1 differentially regulates mitochondrial complex activities to reduce glutathione loss and mitigate ferroptosis.
Histone deacetylase inhibitor pracinostat suppresses colorectal cancer by inducing CDK5-Drp1 signaling-mediated peripheral mitofission.
Scorpion venom heat-resistant peptide alleviates mitochondrial dynamics imbalance induced by PM(2.5) exposure by downregulating the PGC-1α/SIRT3 signaling pathway.
MicroRNA-129-1-3p attenuates autophagy-dependent cell death by targeting MCU in granulosa cells of laying hens under H(2)O(2)-induced oxidative stress.
Polydatin improves vascular endothelial function by maintaining mitochondrial homeostasis under high glucose conditions.
The mitochondrial fusion-associated protein MFN2 can be used as a novel prognostic molecule for clear cell renal cell carcinoma.
TCH-165 attenuates cardiac ischaemia/reperfusion injury by balancing mitochondrial dynamics via increasing proteasome activity.
Down-regulation of the mitochondrial fusion protein Opa1/Mfn2 promotes cardiomyocyte hypertrophy in Su5416/hypoxia-induced pulmonary hypertension rats.
Lycorine promotes IDH1 acetylation to induce mitochondrial dynamics imbalance in colorectal cancer cells.
Endoplasmic reticulum stress induced by turbulence of mitochondrial fusion and fission was involved in stressed cardiomyocyte injury.
High-fat stimulation induces atrial neural remodeling by reducing NO production via the CRIF1/eNOS/P21 axi.
LPGAT1 controls MEGDEL syndrome by coupling phosphatidylglycerol remodeling with mitochondrial transport.
Mitoguardin 1 and 2 promote granulosa cell proliferation by activating AKT and regulating the Hippo-YAP1 signaling pathway.
CCDC127 regulates lipid droplet homeostasis by enhancing mitochondria-ER contacts.
In vivo imaging of mitochondrial DNA mutations using an integrated nano Cas12a sensor.
Disturbed hippocampal histidine metabolism contributes to cognitive impairment induced by recurrent nonsevere hypoglycemia in diabetes.
Low-dose atorvastatin protects skeletal muscle mitochondria in high-fat diet-fed mice with mitochondrial autophagy inhibition and fusion enhancement.
AdipoRon mitigates tau pathology and restores mitochondrial dynamics via AMPK-related pathway in a mouse model of Alzheimer's disease.
miR-27a-3p relieves heat stress-induced mitochondrial damage and aberrant milk protein synthesis through MEK/ERK pathway in BMECs.
Differentiation-inducing factor 1 activates cofilin through pyridoxal phosphatase and AMP-activated protein kinase, resulting in mitochondrial fission.
High uric acid aggravates apoptosis of lung epithelial cells induced by cigarette smoke extract through downregulating PRDX2 in chronic obstructive pulmonary disease.
Mitochondrial dynamics define muscle fiber type by modulating cellular metabolic pathways.
QiShenYiQi dripping pill alleviates myocardial ischemia-induced ferroptosis via improving mitochondrial dynamical homeostasis and biogenesis.
Pathological convergence of APP and SNCA deficiency in hippocampal degeneration of young rats.
Acacetin inhibits myocardial mitochondrial dysfunction by activating PI3K/AKT in SHR rats fed with fructose.
SZC-6, a small-molecule activator of SIRT3, attenuates cardiac hypertrophy in mice.
Mitofusin-2 mediates cannabidiol-induced neuroprotection against cerebral ischemia in rats.
miR-124-3p improves mitochondrial function of renal tubular epithelial cells in db/db mice.
HC067047 as a potent TRPV4 inhibitor repairs endotoxemia colonic injury.
Mitoguardin2 Is Associated With Hyperandrogenism and Regulates Steroidogenesis in Human Ovarian Granulosa Cells.
TREM-1 triggers necroptosis of macrophages through mTOR-dependent mitochondrial fission during acute lung injury.
Macrophage Inactivation by Small Molecule Wedelolactone via Targeting sEH for the Treatment of LPS-Induced Acute Lung Injury.
MFN1 augmentation prevents retinal degeneration in a Charcot-Marie-Tooth type 2A mouse model.
Ketogenic diets composed of long-chain and medium-chain fatty acids induce cardiac fibrosis in mice.
SS-31 alleviated nociceptive responses and restored mitochondrial function in a headache mouse model via Sirt3/Pgc-1α positive feedback loop.
Endothelial progenitor cell-derived exosomes inhibit pulmonary artery smooth muscle cell in vitro proliferation and resistance to apoptosis by modulating the Mitofusin-2 and Ras-Raf-ERK1/2 signaling pathway.
High-fat diet causes mitochondrial damage and downregulation of mitofusin-2 and optic atrophy-1 in multiple organs.
Daytime-restricted feeding enhances running endurance without prior exercise in mice.
Hydrogen sulfide alleviates mitochondrial damage and ferroptosis by regulating OPA3-NFS1 axis in doxorubicin-induced cardiotoxicity.
Mechanical force induces mitophagy-mediated anaerobic oxidation in periodontal ligament stem cells.
A proximity labeling strategy enables proteomic analysis of inter-organelle membrane contacts.
Imbalance in ALR ubiquitination accelerates the progression of nonalcoholic steatohepatitis to hepatocellular carcinoma.
Oligomeric CHMP7 mediates three-way ER junctions and ER-mitochondria interactions.
N-acetyl-L-cysteine alleviates FUNDC1-mediated mitophagy by regulating mitochondrial dynamics in type 1 diabetic nephropathy canine.
Polypropylene nanoplastic exposure leads to lung inflammation through p38-mediated NF-κB pathway due to mitochondrial damage.
Adaptive exhaustion during prolonged intermittent hypoxia causes dysregulated skeletal muscle protein homeostasis.
Phosphodiesterase 4B activation exacerbates pulmonary hypertension induced by intermittent hypoxia by regulating mitochondrial injury and cAMP/PKA/p-CREB/PGC-1α signaling.
Honokiol alleviated neurodegeneration by reducing oxidative stress and improving mitochondrial function in mutant SOD1 cellular and mouse models of amyotrophic lateral sclerosis.
PKM2-mediated neuronal hyperglycolysis enhances the risk of Parkinson's disease in diabetic rats.
Osthole: A potential AMPK agonist that inhibits NLRP3 inflammasome activation by regulating mitochondrial homeostasis for combating rheumatoid arthritis.
Mitochondrial Transfer Regulates Cell Fate Through Metabolic Remodeling in Osteoporosis.
MiR-130a-3p regulates FUNDC1-mediated mitophagy by targeting GJA1 in myocardial ischemia/reperfusion injury.
Identification and validation of a novel prognostic signature based on mitochondria and oxidative stress related genes for glioblastoma.
METTL14-dependent maturation of pri-miR-17 regulates mitochondrial homeostasis and induces chemoresistance in colorectal cancer.
Stomatin-like protein 2 deficiency exacerbates adverse cardiac remodeling.
SIRT3-dependent mitochondrial redox homeostasis mitigates CHK1 inhibition combined with gemcitabine treatment induced cardiotoxicity in hiPSC-CMs and mice.
Nogo-B mediates endothelial oxidative stress and inflammation to promote coronary atherosclerosis in pressure-overloaded mouse hearts.
BNIP3 overexpression may promote myeloma cell apoptosis by enhancing sensitivity to bortezomib via the p38 MAPK pathway.
Zearalenone promotes porcine ESCs apoptosis by enhancing Drp1-mediated mitochondrial fragmentation and activating the JNK pathway.
Effects of dapagliflozin monotherapy and combined aerobic exercise on skeletal muscle mitochondrial quality control and insulin resistance in type 2 diabetes mellitus rats.
Ramelteon attenuates renal ischemia and reperfusion injury through reducing mitochondrial fission and fusion and inflammation.
The Binding of HSPA8 and Mitochondrial ALDH2 Mediates Oxygen-Glucose Deprivation-Induced Fibroblast Senescence.
Cirsiliol induces autophagy and mitochondrial apoptosis through the AKT/FOXO1 axis and influences methotrexate resistance in osteosarcoma.
Ubiquitination of Ku70 by Parkin promotes apoptosis of lens epithelial cells.
Phospholipase A2-activating protein induces mitophagy through anti-apoptotic MCL1-mediated NLRX1 oligomerization.
Advanced oxidation protein products induce Paneth cells defects by endoplasmic reticulum stress in Crohn's disease.
Diosgenin Targets CaMKK2 to Alleviate Type II Diabetic Nephropathy through Improving Autophagy, Mitophagy and Mitochondrial Dynamics.
Correction: Tang et al. Vitamin K2 Modulates Mitochondrial Dysfunction Induced by 6-Hydroxydopamine in SH-SY5Y Cells via Mitochondrial Quality-Control Loop. Nutrients 2022, 14, 1504.
Aristolochic acid I exposure triggers ovarian dysfunction by activating NLRP3 inflammasome and affecting mitochondrial homeostasis.
Mitochondria-associated endoplasmic reticulum membranes dysfunction contributes to PARP-1-dependent cell death under oxidative stress in retinal precursor cells.
Inhibition of mitochondrial VDAC1 oligomerization alleviates apoptosis and necroptosis of retinal neurons following OGD/R injury.
Small molecule agonist of mitochondrial fusion repairs mitochondrial dysfunction.
Molybdenum and Cadmium Co-induce Mitochondrial Quality Control Disorder via FUNDC1-Mediated Mitophagy in Sheep Kidney.
Administration of miR-195 Inhibitor Enhances Memory Function Through Improving Synaptic Degradation and Mitochondrial Dysfunction of the Hippocampal Neurons in SAMP8 Mice.
Selenium Attenuates TBHP-Induced Apoptosis of Nucleus Pulposus Cells by Suppressing Mitochondrial Fission through Activating Nuclear Factor Erythroid 2-Related Factor 2.
Dexmedetomidine Can Enhance PINK1/Parkin-Mediated Mitophagy in MPTP-Induced PD Mice Model by Activating AMPK.
Blockage of Fibronectin 1 Ameliorates Myocardial Ischemia/Reperfusion Injury in Association with Activation of AMP-LKB1-AMPK Signaling Pathway.
Change in Oxidative Stress and Mitochondrial Dynamics in Response to Elevated Cold-Inducible RNA-Binding Protein in Cardiac Surgery-Associated Acute Kidney Injury.
Docosahexaenoic Acid Alleviates Brain Damage by Promoting Mitophagy in Mice with Ischaemic Stroke.
Appropriate Dose of Dapagliflozin Improves Cardiac Outcomes by Normalizing Mitochondrial Fission and Reducing Cardiomyocyte Apoptosis After Acute Myocardial Infarction.
Cangfudaotan decoction inhibits mitochondria-dependent apoptosis of granulosa cells in rats with polycystic ovarian syndrome.
Mfn2 is responsible for inhibition of the RIG-I/IRF7 pathway and activation of NLRP3 inflammasome in Seneca Valley virus-infected PK-15 cells to promote viral replication.
Intracellular Ca(2+) Signaling and Calcium Release-Activated Calcium Modulator ORAI1 Are Associated With CD4(+) T Lymphocytes in Dairy Cows.
COA3 overexpression promotes non-small cell lung cancer metastasis by reprogramming glucose metabolism.
Non-invasive photobiomodulation treatment in an Alzheimer Disease-like transgenic rat model.
PINK1-Dependent Mitophagy Reduced Endothelial Hyperpermeability and Cell Migration Capacity Under Simulated Microgravity.
Scutellarin Protects Against Mitochondrial Reactive Oxygen Species-Dependent NLRP3 Inflammasome Activation to Attenuate Intervertebral Disc Degeneration.
Mitoquinone mitigates paraquat-induced A549 lung epithelial cell injury by promoting MFN1/MFN2-mediated mitochondrial fusion.
Battery wastewater induces nephrotoxicity via disordering the mitochondrial dynamics.
Gefitinib facilitates PINK1/Parkin-mediated mitophagy by enhancing mitochondrial recruitment of OPTN.
Mannose inhibits the growth of prostate cancer through a mitochondrial mechanism.
Exposure to Benzo(a)pyrene damages mitochondrial function via suppressing mitochondrial melatonin receptors in ovarian corpus luteum during early pregnancy.
Polystyrene microplastics-induced cardiotoxicity in chickens via the ROS-driven NF-κB-NLRP3-GSDMD and AMPK-PGC-1α axes.
Transient Receptor Potential Vanilloid Type 1 Protects Against Pressure Overload-Induced Cardiac Hypertrophy by Promoting Mitochondria-Associated Endoplasmic Reticulum Membranes.
Blocking exosomal secretion aggravates 1,4-benzoquinone-induced mitochondrial fission activated by the AMPK/MFF/Drp1 pathway in HL-60 cells.
Mammary Fibrosis Tendency and Mitochondrial Adaptability in Dairy Cows with Mastitis.
Jian-Pi-Yi-Shen decoction inhibits mitochondria-dependent granulosa cell apoptosis in a rat model of POF.
Renoprotective effect of Tanshinone IIA against kidney injury induced by ischemia-reperfusion in obese rats.
Dihydromyricetin contributes to weight loss via pro-browning mediated by mitochondrial fission in white adipose.
Down-regulating of MFN2 promotes vascular calcification via regulating RAS-RAF-ERK1/2 pathway.
SIRT4 Expression Ameliorates the Detrimental Effect of Heat Stress via AMPK/mTOR Signaling Pathway in BMECs.
Gestational Intermittent Hypoxia Induces Mitochondrial Impairment in the Geniohyoid Muscle of Offspring Rats.
A High-Fat Diet Induces Muscle Mitochondrial Dysfunction and Impairs Swimming Capacity in Zebrafish: A New Model of Sarcopenic Obesity.
PACS-2 Ameliorates Tubular Injury by Facilitating Endoplasmic Reticulum-Mitochondria Contact and Mitophagy in Diabetic Nephropathy.
HSP70 attenuates compression-induced apoptosis of nucleus pulposus cells by suppressing mitochondrial fission via upregulating the expression of SIRT3.
Map, but not EspF, induces breast epithelial cell apoptosis through ERK/DRP-1 pathway.
Chicoric Acid Attenuated Renal Tubular Injury in HFD-Induced Chronic Kidney Disease Mice through the Promotion of Mitophagy via the Nrf2/PINK/Parkin Pathway.
Clueless/CLUH regulates mitochondrial fission by promoting recruitment of Drp1 to mitochondria.
Dioscin relieves diabetic nephropathy via suppressing oxidative stress and apoptosis, and improving mitochondrial quality and quantity control.
Nephrotoxicity evaluation of 3-monochloropropane-1,2-diol exposure in Sprague-Dawley rats using data-independent acquisition-based quantitative proteomics analysis.
Autophagy and mitochondrial dynamics contribute to the protective effect of diosgenin against 3-MCPD induced kidney injury.
Caveolin-1 controls mitochondrial damage and ROS production by regulating fission - fusion dynamics and mitophagy.
A possible new activator of PI3K-Huayu Qutan Recipe alleviates mitochondrial apoptosis in obesity rats with acute myocardial infarction.
Total flavonoids of Selaginella tamariscina (P.Beauv.) Spring ameliorates doxorubicin-induced cardiotoxicity by modulating mitochondrial dysfunction and endoplasmic reticulum stress via activating MFN2/PERK.
Novel Thermosensitive Hydrogel Promotes Spinal Cord Repair by Regulating Mitochondrial Function.
SUMO2-mediated SUMOylation of SH3GLB1 promotes ionizing radiation-induced hypertrophic cardiomyopathy through mitophagy activation.
FUNDC2 promotes liver tumorigenesis by inhibiting MFN1-mediated mitochondrial fusion.
The mitochondrial protein Sideroflexin 3 (SFXN3) influences neurodegeneration pathways in vivo.
Urolithin A protects human dermal fibroblasts from UVA-induced photoaging through NRF2 activation and mitophagy.
Selenium alleviates cadmium-induced aging via mitochondrial quality control in the livers of sheep.
LncRNA ANRIL mediates endothelial dysfunction through BDNF downregulation in chronic kidney disease.
Chronic Hypoxia Inhibits Respiratory Complex IV Activity and Disrupts Mitochondrial Dynamics in the Fetal Guinea Pig Forebrain.
Liraglutide Regulates Mitochondrial Quality Control System Through PGC-1α in a Mouse Model of Parkinson's Disease.
Interfering with mitochondrial dynamics sensitizes glioblastoma multiforme to temozolomide chemotherapy.
Histone deacetylase inhibitors inhibit cervical cancer growth through Parkin acetylation-mediated mitophagy.
Attenuates of NAD(+) impair BMSC osteogenesis and fracture repair through OXPHOS.
Cdk5 Promotes Mitochondrial Fission via Drp1 Phosphorylation at S616 in Chronic Ethanol Exposure-Induced Cognitive Impairment.
Activation of FMS-like tyrosine kinase 3 protects against isoprenaline-induced cardiac hypertrophy by improving autophagy and mitochondrial dynamics.
CEND1 deficiency induces mitochondrial dysfunction and cognitive impairment in Alzheimer's disease.
Spermidine Alleviates Intrauterine Hypoxia-Induced Offspring Newborn Myocardial Mitochondrial Damage in Rats by Inhibiting Oxidative Stress and Regulating Mitochondrial Quality Control.
GABA regulates IL-1β production in macrophages.
Endosomal lipid signaling reshapes the endoplasmic reticulum to control mitochondrial function.
A pivotal role of selective autophagy in mitochondrial quality control: Implications for zinc oxide nanoparticles induced neurotoxicity.
Baicalein suppresses high glucose-induced inflammation and apoptosis in trophoblasts by targeting the miRNA-17-5p-Mfn1/2-NF-κB pathway.
Map of Enteropathogenic Escherichia coli Targets Mitochondria and Triggers DRP-1-Mediated Mitochondrial Fission and Cell Apoptosis in Bovine Mastitis.
Nicotinamide mononucleotide alleviates heat stress-induced oxidative stress and apoptosis in BMECs through reducing mitochondrial damage and endoplasmic reticulum stress.
Phosphorylation of Dynamin-Related Protein 1 (DRP1) Regulates Mitochondrial Dynamics and Skeletal Muscle Wasting in Cancer Cachexia.
Mitochondrial Fusion Potentially Regulates a Metabolic Change in Tibetan Chicken Embryonic Brain During Hypoxia.
Tanshinone IIA Combined With Cyclosporine A Alleviates Lung Apoptosis Induced by Renal Ischemia-Reperfusion in Obese Rats.
Oxyberberine Prevented Lipopolysaccharide-Induced Acute Lung Injury through Inhibition of Mitophagy.
RNA-Seq Profiling to Investigate the Mechanism of Qishen Granules on Regulating Mitochondrial Energy Metabolism of Heart Failure in Rats.
Dl-3-n-Butylphthalide Alleviates Behavioral and Cognitive Symptoms Via Modulating Mitochondrial Dynamics in the A53T-α-Synuclein Mouse Model of Parkinson's Disease.
High-Fat Diet-Induced Mitochondrial Dysfunction Promotes Genioglossus Injury - A Potential Mechanism for Obstructive Sleep Apnea with Obesity.
Cordycepin Decreases Ischemia/Reperfusion Injury in Diabetic Hearts via Upregulating AMPK/Mfn2-dependent Mitochondrial Fusion.
Mitofusin 2 Deficiency Causes Pro-Inflammatory Effects in Human Primary Macrophages.
Tortoise Plastron and Deer Antler Gelatin Prevents Against Neuronal Mitochondrial Dysfunction In Vitro: Implication for a Potential Therapy of Alzheimer's Disease.
Nicotine Causes Mitochondrial Dynamics Imbalance and Apoptosis Through ROS Mediated Mitophagy Impairment in Cardiomyocytes.
Astragaloside II Ameliorated Podocyte Injury and Mitochondrial Dysfunction in Streptozotocin-Induced Diabetic Rats.
Biochanin A Inhibits Glioblastoma Growth via Restricting Glycolysis and Mitochondrial Oxidative Phosphorylation.
The E3 ubiquitin ligase TRIM31 is involved in cerebral ischemic injury by promoting degradation of TIGAR.
MicroRNA-214 contributes to Ang II-induced cardiac hypertrophy by targeting SIRT3 to provoke mitochondrial malfunction.
CISD3 inhibition drives cystine-deprivation induced ferroptosis.
Effects of andrographolide on renal tubulointersticial injury and fibrosis. Evidence of its mechanism of action.
Inhibition of ER stress attenuates kidney injury and apoptosis induced by 3-MCPD via regulating mitochondrial fission/fusion and Ca(2+) homeostasis.
SIRT3 protects bovine mammary epithelial cells from heat stress damage by activating the AMPK signaling pathway.
Trib1 deficiency causes brown adipose respiratory chain depletion and mitochondrial disorder.
Global ubiquitylation analysis of mitochondria in primary neurons identifies endogenous Parkin targets following activation of PINK1.
Acetaldehyde Dehydrogenase 2 regulates HMG-CoA reductase stability and cholesterol synthesis in the liver.
Dihydromyricetin attenuates heat stress-induced apoptosis in dairy cow mammary epithelial cells through suppressing mitochondrial dysfunction.
The AMPK-MFN2 axis regulates MAM dynamics and autophagy induced by energy stresses.
LACTB suppresses melanoma progression by attenuating PP1A and YAP interaction.
Mitocytosis, a migrasome-mediated mitochondrial quality-control process.
Conditioned medium from induced pluripotent stem cell-derived mesenchymal stem cells accelerates cutaneous wound healing through enhanced angiogenesis.
High Dietary Fat Consumption Impairs Axonal Mitochondrial Function In Vivo.
Tanshinone IIA combined with CsA inhibit myocardial cell apoptosis induced by renal ischemia-reperfusion injury in obese rats.
ALS/FTD mutations in UBQLN2 are linked to mitochondrial dysfunction through loss-of-function in mitochondrial protein import.
Sulforaphane Balances Ca(2+) Homeostasis Injured by Excessive Fat via Mitochondria-Associated Membrane (MAM).
DHA exhibits synergistic therapeutic efficacy with cisplatin to induce ferroptosis in pancreatic ductal adenocarcinoma via modulation of iron metabolism.
miR-34a-5p regulates PINK1-mediated mitophagy via multiple modes.
Mesenchymal stem cells ameliorate lipid metabolism through reducing mitochondrial damage of hepatocytes in the treatment of post-hepatectomy liver failure.
CHIP protects against MPP(+)/MPTP-induced damage by regulating Drp1 in two models of Parkinson's disease.
DsbA-L deficiency in T cells promotes diet-induced thermogenesis through suppressing IFN-γ production.
OPA1 haploinsufficiency due to a novel splicing variant resulting in mitochondrial dysfunction without mitochondrial DNA depletion.
Oxidative stress-induced mitophagy is suppressed by the miR-106b-93-25 cluster in a protective manner.
PINCH-1 promotes Δ(1)-pyrroline-5-carboxylate synthase expression and contributes to proline metabolic reprogramming in lung adenocarcinoma.
Caffeine promotes angiogenesis through modulating endothelial mitochondrial dynamics.
Possible relationship between mitochondrial changes and oxidative stress under low dose-rate irradiation.
LKB1/AMPKα signaling pathway and mitochondrial fission/fusion dynamics regulate apoptosis induced by 3-chlorpropane-1,2-diol in HEK293 cells.
Extract of Cynomorium songaricum ameliorates mitochondrial ultrastructure impairments and dysfunction in two different in vitro models of Alzheimer's disease.
Ginsenoside Rg5 Improves Insulin Resistance and Mitochondrial Biogenesis of Liver via Regulation of the Sirt1/PGC-1α Signaling Pathway in db/db Mice.
VPS13D interacts with VCP/p97 and negatively regulates endoplasmic reticulum-mitochondria interactions.
Mst1 Knockout Alleviates Mitochondrial Fission and Mitigates Left Ventricular Remodeling in the Development of Diabetic Cardiomyopathy.
Deletion of Bmal1 Impairs Pancreatic β-Cell Function via Mitochondrial Signaling Pathway.
Role of Nrf2 in Lipopolysaccharide-Induced Acute Kidney Injury: Protection by Human Umbilical Cord Blood Mononuclear Cells.
Proteomic Profile of Mouse Brain Aging Contributions to Mitochondrial Dysfunction, DNA Oxidative Damage, Loss of Neurotrophic Factor, and Synaptic and Ribosomal Proteins.
A Long-Term Enriched Environment Ameliorates the Accelerated Age-Related Memory Impairment Induced by Gestational Administration of Lipopolysaccharide: Role of Plastic Mitochondrial Quality Control.
Bu-Yin-Qian-Zheng Formula Ameliorates MPP(+)-Induced Mitochondrial Dysfunction in Parkinson's Disease via Parkin.
Promotion of mitochondrial fusion protects against developmental PBDE-47 neurotoxicity by restoring mitochondrial homeostasis and suppressing excessive apoptosis.
Ferroptosis mediated by the interaction between Mfn2 and IREα promotes arsenic-induced nonalcoholic steatohepatitis.
The renoprotective effect of diosgenin on aristolochic acid I-induced renal injury in rats: impact on apoptosis, mitochondrial dynamics and autophagy.
A substrate-trapping strategy to find E3 ubiquitin ligase substrates identifies Parkin and TRIM28 targets.
Drp1-dependent mitochondrial fission contributes to Cr(VI)-induced mitophagy and hepatotoxicity.
PINCH-1 regulates mitochondrial dynamics to promote proline synthesis and tumor growth.
HIF-1α ameliorates tubular injury in diabetic nephropathy via HO-1-mediated control of mitochondrial dynamics.
PDK4 promotes vascular calcification by interfering with autophagic activity and metabolic reprogramming.
DIPK2A promotes STX17- and VAMP7-mediated autophagosome-lysosome fusion by binding to VAMP7B.
ChREBP-β regulates thermogenesis in brown adipose tissue.
Oroxylin a promotes PGC-1α/Mfn2 signaling to attenuate hepatocyte pyroptosis via blocking mitochondrial ROS in alcoholic liver disease.
Melatonin regulates mitochondrial dynamics and alleviates neuron damage in prion diseases.
Tetrahydroxy stilbene glycoside alleviated inflammatory damage by mitophagy via AMPK related PINK1/Parkin signaling pathway.
Chicken thalamic injury induced by copper (II) or / and arsenite exposure involves oxidative stress and inflammation-induced apoptosis.
Tongmai formula improves cardiac function via regulating mitochondrial quality control in the myocardium with ischemia/reperfusion injury.
Sodium-glucose cotransporter 2 inhibition attenuates protein overload in renal proximal tubule via suppression of megalin O-GlcNacylation in progressive diabetic nephropathy.
Klf5 down-regulation induces vascular senescence through eIF5a depletion and mitochondrial fission.
TLR4 knockout upregulates the expression of Mfn2 and PGC-1α in a high-fat diet and ischemia-reperfusion mice model of liver injury.
Heat stress induces apoptosis through disruption of dynamic mitochondrial networks in dairy cow mammary epithelial cells.
Exogenous H(2)S Promoted USP8 Sulfhydration to Regulate Mitophagy in the Hearts of db/db Mice.
DsbA-L deficiency exacerbates mitochondrial dysfunction of tubular cells in diabetic kidney disease.
Spermidine Prevents Heart Injury in Neonatal Rats Exposed to Intrauterine Hypoxia by Inhibiting Oxidative Stress and Mitochondrial Fragmentation.
Impaired Mitochondrial Fusion and Oxidative Phosphorylation Triggered by High Glucose Is Mediated by Tom22 in Endothelial Cells.
The Neuroprotective Effect of Hemin and the Related Mechanism in Sevoflurane Exposed Neonatal Rats.
Da-Bu-Yin-Wan and Qian-Zheng-San Ameliorate Mitochondrial Dynamics in the Parkinson's Disease Cell Model Induced by MPP().
Mitochondrial dysfunction in endothelial cells induced by airborne fine particulate matter (<2.5 μm).
DsbA-L ameliorates high glucose induced tubular damage through maintaining MAM integrity.
Roles of mitochondrial fission inhibition in developmental fluoride neurotoxicity: mechanisms of action in vitro and associations with cognition in rats and children.
Reduced mitochondrial fusion and Huntingtin levels contribute to impaired dendritic maturation and behavioral deficits in Fmr1-mutant mice.
CDDO-Me Selectively Attenuates CA1 Neuronal Death Induced by Status Epilepticus via Facilitating Mitochondrial Fission Independent of LONP1.
Mitochondrial Dynamics Is Critical for the Full Pluripotency and Embryonic Developmental Potential of Pluripotent Stem Cells.
The human Obg protein GTPBP10 is involved in mitoribosomal biogenesis.
In Vivo Deletion of β-Cell Drp1 Impairs Insulin Secretion Without Affecting Islet Oxygen Consumption.
Phosphorylation of Parkin at serine 131 by p38 MAPK promotes mitochondrial dysfunction and neuronal death in mutant A53T α-synuclein model of Parkinson's disease.
Mutant APP and amyloid beta-induced defective autophagy, mitophagy, mitochondrial structural and functional changes and synaptic damage in hippocampal neurons from Alzheimer's disease.
GLUT10 maintains the integrity of major arteries through regulation of redox homeostasis and mitochondrial function.
Hypertonia-linked protein Trak1 functions with mitofusins to promote mitochondrial tethering and fusion.
DNA damage triggers tubular endoplasmic reticulum extension to promote apoptosis by facilitating ER-mitochondria signaling.
Neuroprotective Effect and Mechanism of Thiazolidinedione on Dopaminergic Neurons In Vivo and In Vitro in Parkinson's Disease.
Succinate promotes stem cell migration through the GPR91-dependent regulation of DRP1-mediated mitochondrial fission.
Lysosomal Proteolysis Is Associated With Exercise-Induced Improvement of Mitochondrial Quality Control in Aged Hippocampus.
Impaired mitochondrial fusion, autophagy, biogenesis and dysregulated lipid metabolism is associated with preeclampsia.
Fatty acid synthesis is critical for stem cell pluripotency via promoting mitochondrial fission.
Maternal exercise upregulates mitochondrial gene expression and increases enzyme activity of fetal mouse hearts.
Salvianolic acid B inhibits mitochondrial dysfunction by up-regulating mortalin.
TRPC6-mediated ERK1/2 phosphorylation prevents dentate granule cell degeneration via inhibiting mitochondrial elongation.
An mtDNA mutation accelerates liver aging by interfering with the ROS response and mitochondrial life cycle.
Hydrogen Sulphide modulating mitochondrial morphology to promote mitophagy in endothelial cells under high-glucose and high-palmitate.
The inflammatory responses in Cu-mediated elemental imbalance is associated with mitochondrial fission and intrinsic apoptosis in Gallus gallus heart.
Antagonistic effects of selenium on cadmium-induced apoptosis by restoring the mitochondrial dynamic equilibrium and energy metabolism in chicken spleens.
MiR-106b-mediated Mfn2 suppression is critical for PKM2 induced mitochondrial fusion.
Exogenous H2S modulates mitochondrial fusion-fission to inhibit vascular smooth muscle cell proliferation in a hyperglycemic state.
Dysfunctional tubular endoplasmic reticulum constitutes a pathological feature of Alzheimer's disease.
SAMM50 Affects Mitochondrial Morphology through the Association of Drp1 in Mammalian Cells.
Mic60/Mitofilin determines MICOS assembly essential for mitochondrial dynamics and mtDNA nucleoid organization.
Lost region in amyloid precursor protein (APP) through TALEN-mediated genome editing alters mitochondrial morphology.
ABT737 reverses cisplatin resistance by regulating ER-mitochondria Ca2+ signal transduction in human ovarian cancer cells.
Protective effects of reduced dynamin-related protein 1 against amyloid beta-induced mitochondrial dysfunction and synaptic damage in Alzheimer's disease.
FUS Interacts with HSP60 to Promote Mitochondrial Damage.
Relocation of p25α/tubulin polymerization promoting protein from the nucleus to the perinuclear cytoplasm in the oligodendroglia of sporadic and COQ2 mutant multiple system atrophy.
Inhibition of mitochondrial fission prevents cell cycle progression in lung cancer.
Mitochondrial remodeling following fission inhibition by 15d-PGJ2 involves molecular changes in mitochondrial fusion protein OPA1.
Li Z, Xu W, Ren S, Zheng Q, Xing J
Phytomedicine : international journal of phytotherapy and phytopharmacology 2026 May;154:158035
Phytomedicine : international journal of phytotherapy and phytopharmacology 2026 May;154:158035
The purinergic receptor P2rx7 mediated ATP sensing is required to prevent bone aging by directing mitochondrial fitness of MSCs.
Zhuang Z, Han C, Cai M, Li M, Lin S, Chen L, Zhu Z, Zhang H, Xing C, Han B, Yang R
Journal of advanced research 2026 Mar;81:349-364
Journal of advanced research 2026 Mar;81:349-364
Targeting NME3 to Restore Mitochondrial Fission-Fusion Balance Defines a Novel Disease-Modifying Strategy for Parkinson's Disease.
Qiao C, Hu XQ, Xu SH, Yao MF, Liu JP, Cao L
CNS neuroscience & therapeutics 2026 Mar;32(3):e70822
CNS neuroscience & therapeutics 2026 Mar;32(3):e70822
ACADVL upregulation is associated with placental ferroptosis in intrahepatic cholestasis of pregnancy.
Tang M, Cai J, Zhang L, Xiong L, Gong X, Fu J, Wang P, Luo M, Liu H, Ye Y, Yu M, Yu H, Xing S, Yang X
Biochimica et biophysica acta. Molecular and cell biology of lipids 2026 Mar;1871(2):159711
Biochimica et biophysica acta. Molecular and cell biology of lipids 2026 Mar;1871(2):159711
Complement 5a receptor 2 attenuates diabetic kidney disease by promoting mitochondria-associated endoplasmic reticulum membrane formation mediated by PSS-MFN2 interaction.
Zhao YY, Wang YH, Li ZH, Chang DY, Nie L, Zhao MH, Tang SCW, Chen M
Cell discovery 2026 Mar 31;12(1)
Cell discovery 2026 Mar 31;12(1)
Mitofusin-2 suppresses tumor immune escape through EGFR/STAT3-mediated PD-L1 transcription.
Liu Y, Wang N, Li Z, Li N, Hui F, Wang X, Tang G, Zhang Q, Yu G, Liu S, Ding Y
Cell death & disease 2026 Mar 27;17(1)
Cell death & disease 2026 Mar 27;17(1)
Dendrobium officinale polysaccharides alleviate atopic dermatitis in vivo and in vitro through inhibition of inflammation and mitochondrial dysfunction.
Zeng B, Jiang G, Wang C, Zhou H, Zhang Y, Yan YN, Chen Z, Zhang L, Li X, Xie M, Yang Z, Wang H
Journal of molecular histology 2026 Mar 26;57(2)
Journal of molecular histology 2026 Mar 26;57(2)
Cannabidiol attenuates the LPS/D-Galactosamine-induced acute liver injury by inhibiting parkin-mediated ubiquitination of MFN2.
Zhan Z, Jiang Y, Chen S, Yang Q, Pan G, Liu Y, Fang W, Chen R, Tang L, Lin C
Journal of ethnopharmacology 2026 Mar 25;359:121067
Journal of ethnopharmacology 2026 Mar 25;359:121067
PCSK9 Inhibitor Alirocumab Improves Diabetic Cardiomyopathy Through the ERK/p38 MAPK Signaling Pathway.
Lin S, Wu B, Sun S, Sun T
International journal of molecular sciences 2026 Mar 2;27(5)
International journal of molecular sciences 2026 Mar 2;27(5)
Aerobic exercise improve physical endurance and muscle function by ameliorating oxidative stress and modulating mitochondrial dynamics in aged skeletal muscle.
Zheng F, Zhou J, Cao Y, Lin L, Wang W, Zhang L, Li W, Li T, Wang L
Journal of physiology and biochemistry 2026 Mar 17;82(1)
Journal of physiology and biochemistry 2026 Mar 17;82(1)
Electroacupuncture mitigates oxidative stress and neuroinflammation in Parkinson's disease via mitigating autophagy-lysosome dysfunction.
Shan Y, Sha S, Dong S, Han S, Huang K, Sun C, Zhang Z, Luo E
Pathology, research and practice 2026 Jun;282:156438
Pathology, research and practice 2026 Jun;282:156438
Intermittent fasting attenuates ovarian chronic inflammation in obese mice by inhibiting the CXCL12-CXCR4 axis.
Chen X, Han Z, Yu X, Hao X
International immunopharmacology 2026 Jun 15;179:116603
International immunopharmacology 2026 Jun 15;179:116603
Sennoside A alleviates HFD-induced MAFLD by protecting intestinal barrier function through TLR4/NF-κB and mitochondrial quality control.
Ma L, Yuan C, Cao X, Sun Y
Pathology, research and practice 2026 Jul;283:156482
Pathology, research and practice 2026 Jul;283:156482
Echinacoside improves antioxidant responses and angiogenesis through Parkin-MFN2-mediated mitophagy to promote diabetic wound healing.
Li Z, Li Z, Li Q, Miao R, Ma Y, Wei S, Mao J, Wang X, Zeng X, Zhou Y, Ye J, Xia W, Lin C, Mao C
Free radical biology & medicine 2026 Jul;250:436-452
Free radical biology & medicine 2026 Jul;250:436-452
Caveolin-1 deficiency exacerbates liver fibrosis by driving lipid metabolic reprogramming in hepatic stellate cells via DRP1-mediated mitochondrial fission.
Wang Y, Wang X, Lin J, Zhang W, Sun Y, Geng Q, Chen S, Zhang C, Jin L, Hu C
Free radical biology & medicine 2026 Jul;250:203-215
Free radical biology & medicine 2026 Jul;250:203-215
Overexpression of mitofusin 2 ameliorates inflammation and oxidative stress in lipopolysaccharide-induced mastitis model by regulating phosphofurin acidic cluster sorting protein 2.
Zhou X, Zhang Y, Ma H, Fu S, Liu J, Guo W, Tian X, Huang B
Animal models and experimental medicine 2026 Jan;9(1):154-167
Animal models and experimental medicine 2026 Jan;9(1):154-167
The Neuroprotective Role of Ginsenoside Rg1 Against Cerebral Ischemia-Reperfusion Damage Through Inhibition of Mitophagy via Blocking Mitophagosome-Lysosome Fusion.
Ai L, Ren H, Wang Y, Liu M, Qiu Y, Feng J, Dai R, Fu W, Wang Y, Xi Z, Xu H, Wang F
Cell proliferation 2026 Jan;59(1):e70071
Cell proliferation 2026 Jan;59(1):e70071
High‑intensity exercise training inhibits excessive autophagy in the hyperlipidemic myocardium of ApoE(‑/‑) mice via the NAD(+)‑mediated SIRT1/MFN2 pathway.
Gao S, Yao W, Yang J, Liu Y, Pei Z
Molecular medicine reports 2026 Jan;33(1)
Molecular medicine reports 2026 Jan;33(1)
Down-regulation of lipocalin-2 alleviates depressive-like behaviors in mice through modulation of microglial activation.
Yu X, Gao S, Chen Y, Ye L, Wang B, Xu L, Sun A, Liang C, Lu S, Li X, Fan Z, Wang Y
Neurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics 2026 Jan;23(1):e00862
Neurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics 2026 Jan;23(1):e00862
Lobetyolin alleviates microglial inflammation by activating CK2α/Opa1-mediated mitochondrial fusion in ischemic stroke.
Qin N, Liu R, Deng R, Jia W, Yang Y, Sun J, Gao S, Zhu T
Phytomedicine : international journal of phytotherapy and phytopharmacology 2026 Jan;150:157651
Phytomedicine : international journal of phytotherapy and phytopharmacology 2026 Jan;150:157651
Macelignan, a lignan from Myristica fragrans Houtt., rescues mitochondrial homeostasis and prevents cognitive decline in vascular dementia by modulating the mTOR-Mitophagy axis.
Qi Z, Chu X, Li S, Bai Q, Ding N, Yan G, Yu H, Cui C
Journal of ethnopharmacology 2026 Jan 30;355(Pt A):120603
Journal of ethnopharmacology 2026 Jan 30;355(Pt A):120603
Endoplasmic Reticulum Stress Induced by Turbulence of Mitochondrial Fusion and Fission Was Involved in Isoproterenol-Induced H9c2 Cell Injury.
Zhang S, Chen L, Jia F, Zhang S, Zhang H, Shi W, Cong B
International journal of molecular sciences 2026 Jan 30;27(3)
International journal of molecular sciences 2026 Jan 30;27(3)
Molecular mechanism of berberine in ameliorating leptin resistance and mitochondrial dysfunction through the TRIB1-C/EBPα axis in obesity.
Zhang X, Zhang C, Meng X, Tang J
Chinese medicine 2026 Jan 26;21(1):55
Chinese medicine 2026 Jan 26;21(1):55
BAP31 Modulates Mitochondrial Homeostasis Through PINK1/Parkin Pathway in MPTP Parkinsonism Mouse Models.
Zhang W, Meng S, Hao Z, Zhu X, Cao L, Yuan Q, Wang B
Cells 2026 Jan 12;15(2)
Cells 2026 Jan 12;15(2)
ER stress disrupts MFN2-related mitophagy via HRD1-PINK1/ parkin axis in bovine embryos.
Shi SM, Liu LY, Chi ZC, Qu LY, Li JH, Jia GL, He YY, Jin YX, Zhang MJ, Yu XF
Theriogenology 2026 Jan 1;249:117659
Theriogenology 2026 Jan 1;249:117659
The UBC/SIRT5/DRP1 axis regulates mitochondrial dynamics to alleviate Staphylococcus aureus-induced oxidative stress and senescence in bovine mammary epithelial cells.
Hu H, Jiang N, Liu J, Bi J, Liu X, Xu B, Cao Y, Guo W, Fu S
PLoS pathogens 2026 Feb;22(2):e1013975
PLoS pathogens 2026 Feb;22(2):e1013975
Mesenchymal Stem Cell-derived Exosomes Alleviate Oxidative Stress and Brain Injuries Through Promoting OPA1 Mediated Mitochondrial Fusion After Intracerebral Hemorrhage.
Xu Y, Du Y, Hu Q, Wang P, Cai Y, Zhou G, Liu H, Guo W
Molecular neurobiology 2026 Feb 7;63(1):426
Molecular neurobiology 2026 Feb 7;63(1):426
AMPK Deficiency Induces Corneal Epithelial Barrier Dysfunction by Modulating Energy Homeostasis.
Yang Y, Yan K, Tang Y, Liu Z, Zhu L, Wei M, Huang C, Liu Z, Zhao D, Ren S
Investigative ophthalmology & visual science 2026 Feb 2;67(2):47
Investigative ophthalmology & visual science 2026 Feb 2;67(2):47
The HEAT repeat protein MROH7 regulates the inflammatory macrophage response via LBP acetylation.
Zhang H, Fu J, Guo Y, Liu S, Mei X, Zeng X, Ren W
Cell chemical biology 2026 Feb 19;33(2):169-182.e5
Cell chemical biology 2026 Feb 19;33(2):169-182.e5
Redox switch C674 in SERCA2 triggers Ca(2+)-calcineurin-MCU-Drp1 cascade and pulmonary vascular remodeling.
Chen H, Qiu YX, Xie YF, Chen X, Xiang YY, Zhang HL, Yu WM, Hu PP, Wang LT, Wu FH, Tong XY
Free radical biology & medicine 2026 Feb 16;244:380-394
Free radical biology & medicine 2026 Feb 16;244:380-394
Trimethylamine-N-oxide disrupts spermatogenesis by inducing mitochondrial oxidative stress injury through Hippo signaling.
Wang S, Ma G, Qi C, Cheng S, Lai H, Zhou L, Wu G, Chen Z, Mao X, Jing T, He Y, Zhou H
Free radical biology & medicine 2026 Feb 1;243:452-465
Free radical biology & medicine 2026 Feb 1;243:452-465
Fibrotic scar formation after cerebral ischemic stroke: Targeting the Sonic hedgehog signaling pathway for scar reduction.
Wen J, Tang H, Tian M, Wang L, Yang Q, Zhao Y, Li X, Ren Y, Wang J, Zhou L, Tan Y, Wu H, Cai X, Wang Y, Cao H, Xu J, Yang Q
Neural regeneration research 2026 Feb 1;21(2):756-768
Neural regeneration research 2026 Feb 1;21(2):756-768
A coenzyme-based "interface-welding" hydrogel coating for titanium implants promotes diabetic osseointegration by regulating mitochondrial dynamics.
Duan Q, Geng W, He T, Yang J, Li K, Yang F, Fu Z, Liao X, Luo H, Zhao P, Cai K
Biomaterials 2026 Aug;331:124115
Biomaterials 2026 Aug;331:124115
Hippocampal HDAC7 induces perioperative neurocognitive disorders via an NF-κB-MFN2-ACSL4 ferroptosis pathway.
Guo J, Chi W, Zhang K, Huang Y, Zhang B, Guo X, Meng F
Cellular signalling 2026 Aug;144:112531
Cellular signalling 2026 Aug;144:112531
Mitochondrial TRPV1 exacerbates cognitive deficits in sepsis-associated encephalopathy by driving microglial metabolic reprogramming.
Fan Z, Du L, Yin L, Liu H, Li M, Li J, Liu F, Yang L, Li J, Wang Q, Wu Y, Ma H, Zhang X
Free radical biology & medicine 2026 Apr;247:448-468
Free radical biology & medicine 2026 Apr;247:448-468
The integrated stress response suppresses PINK1-dependent mitophagy by preserving mitochondrial import efficiency.
Yang M, Mo Z, Walsh K, Liu W, Irahal IN, Arnoult D, Guo X
Nature communications 2026 Apr 9;
Nature communications 2026 Apr 9;
Florfenicol impairs steroid hormone secretion in bovine ovarian granulosa cells: Involvement of the cAMP/PKA/StAR signaling pathway and oxidative stress.
Zhao J, Zhou X, You B, Cheng B, Hu J, Lu Y, Xu D, Zhang X, Yan C, Gao Q, Liu H, Jin Q
Theriogenology 2026 Apr 23;261:117956
Theriogenology 2026 Apr 23;261:117956
Pestiviruses utilize pyrimidine metabolism to regulate mitophagy for viral replication.
Zhao B, Chen J, Cheng Y, Li Y, Zhong L, Chen J, Bi X, Bai J, Dai Q, Ye Y, Zou L, Wang L, Zhou B
Autophagy 2026 Apr 20;:1-22
Autophagy 2026 Apr 20;:1-22
Metformin Alleviates Liver Metabolic Dysfunction in Polycystic Ovary Syndrome by Activating the Ethe1/Keap1/PINK1 Pathway.
Xie Y, Tian Y, Huang J, Deng W, Li X, Liu Y, Liu H, Gao L, Xie Q, Yu Q
International journal of biological sciences 2025;21(8):3505-3526
International journal of biological sciences 2025;21(8):3505-3526
Astragaloside IV Alleviates H(2)O(2)-Induced Mitochondrial Dysfunction and Inhibits Mitophagy Via PI3K/AKT/mTOR Pathway.
Qi M, Wang Q, Sun R, Cheng Z, Li M, Fan X, Bai F, Yu J
Cardiovascular therapeutics 2025;2025:9549175
Cardiovascular therapeutics 2025;2025:9549175
Augmenter of Liver Regeneration Crotonylation Assists in Mitochondria-ER Contact to Alleviate Hepatic Steatosis.
Wang XL, He JH, Xie P, Wu Y, Dong LY, An W
Cellular and molecular gastroenterology and hepatology 2025;19(3):101436
Cellular and molecular gastroenterology and hepatology 2025;19(3):101436
Metformin Activation of Sirtuin 3 Signaling Regulates Mitochondrial Function Improves Diabetes-Associated Cognitive Impairment.
An JF, Su H, Zhang CQ, Wang XT, Zhang GQ, Fu LY, Xu YN, Tao L, Shen XC
Diabetes, metabolic syndrome and obesity : targets and therapy 2025;18:2317-2330
Diabetes, metabolic syndrome and obesity : targets and therapy 2025;18:2317-2330
Silencing ATF3 mediates mitochondrial homeostasis and improves ischemic stroke through regulating the MAPK signaling pathway.
Li H, Zhang F, Zhang C, Zhou M, Liu Q, Zeng G
Frontiers in molecular neuroscience 2025;18:1554802
Frontiers in molecular neuroscience 2025;18:1554802
MFN2-a multifaceted guardian against Parkinson's pathophysiology: mitochondria, ferroptosis, inflammation and oxidative stress.
Cheng Y, Zhai H, Liu Y, Yang Y, Fang B, Song M, Wang X, Zhong P
Frontiers in aging neuroscience 2025;17:1611958
Frontiers in aging neuroscience 2025;17:1611958
Optineurin overexpression ameliorates neurodegeneration through regulating neuroinflammation and mitochondrial quality in a murine model of amyotrophic lateral sclerosis.
Zhao S, Chen R, An Y, Zhang Y, Ma C, Gao Y, Lu Y, Yang F, Bai X, Zhang J
Frontiers in aging neuroscience 2025;17:1522073
Frontiers in aging neuroscience 2025;17:1522073
Bavachin suppresses proliferation of laryngopharyngeal cancer by regulating the STAT3 and MAPK signaling pathways.
Yang X, Ding Z, Hua H, Gan R, Meng D, Zang Y, Xiao H, Wang D, Jiang W, Si D, Wei X, Zhang M, Zhang H, Gao C
Journal of Cancer 2025;16(7):2339-2352
Journal of Cancer 2025;16(7):2339-2352
Mitochondrial dysfunction is a hallmark of woody breast myopathy in broiler chickens.
Greene ES, Chen PR, Walk C, Bedford M, Dridi S
Frontiers in physiology 2025;16:1543788
Frontiers in physiology 2025;16:1543788
Calcium dysregulation disrupts mitochondrial homeostasis by interfering AMPK/Drp1 pathway to aggravate plaque progression and instability.
Hu P, Liu M, Wu T, Zhang Y, Liu C, Wang L, Zhang W, Que Y, You J, Yu W, Tong X
Theranostics 2025;15(15):7567-7583
Theranostics 2025;15(15):7567-7583
Vine-inspired zinc-ion modified black phosphorus coating accelerates bone tissue infiltration of 3D printed scaffolds.
Li D, Dai D, Wang J, Wang Y, Tian Y, Zhang C
Theranostics 2025;15(11):5073-5086
Theranostics 2025;15(11):5073-5086
Human milk-derived 5'-UMP promotes thermogenesis and mitochondrial biogenesis to ameliorate obesity.
Zhang L, Peng Z, Lin C, Hu H, Du J, Huang S, Huang S, Gao J, Guo X
Frontiers in nutrition 2025;12:1661778
Frontiers in nutrition 2025;12:1661778
Cardioprotective effect of Yiqi Huoxue decoction on post-myocardial infarction injury mediated by Ca(2+) flux through MAMs.
Li Y, Du T, Zhang Y, Lu Y, Li X, Xie W, Guo S
Frontiers in cardiovascular medicine 2025;12:1596757
Frontiers in cardiovascular medicine 2025;12:1596757
Discovery of a novel chalcone-derived covalent Keap1 binder for mitigating cisplatin-induced mitochondrial dysfunction and nephrotoxicity.
Deng Y, Xu L, Jiang Z, Chen L, Zhu G, Xu C, Chu X, Wang L, Niu X, Chen L, Xiao Z, Hu J, Ge G
Redox biology 2025 Sep;85:103737
Redox biology 2025 Sep;85:103737
miR-223-3p Mitigates Mitochondrial Dysfunction and Cementoblast Apoptosis in Orthodontic Root Resorption via FoxO3.
He W, Xu L, Jiang W, Yao S, Fu Y, Cheng Z, Zhang D, Huang L
Journal of periodontal research 2025 Sep;60(9):923-936
Journal of periodontal research 2025 Sep;60(9):923-936
Chimeric deubiquitinase engineering reveals structural basis for specific inhibition of the mitophagy regulator USP30.
Kazi NH, Klink N, Gallant K, Kipka GM, Gersch M
Nature structural & molecular biology 2025 Sep;32(9):1776-1786
Nature structural & molecular biology 2025 Sep;32(9):1776-1786
Gut microbiota regulation by Lactiplantibacillus plantarum SG5 enhances mitochondrial function in Parkinson's disease mice via the GLP-1/PGC-1α pathway.
Qi Y, Xie S, Chen J, Zhang C, Ma X, Yu Y, Yu X, Wang Y
The Journal of nutritional biochemistry 2025 Sep;143:109954
The Journal of nutritional biochemistry 2025 Sep;143:109954
Modulating Macrophage-Nucleus Pulposus Cell Crosstalk via Sequential Drug Delivery Attenuates Disc Degeneration.
Kong X, Hu R, Zhang P, Li Q, Song K, Gu H, Zheng J, Liu S, Liu L, Jin L, Cheng L, Li C, Wei Z
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2025 Sep;12(36):e07178
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2025 Sep;12(36):e07178
Mechanism of mitofusin 2, mitochondria-associated membrane, and the mitochondrial pathway in alleviating oxidative stress and cell senescence in bovine mammary epithelial cells.
Hu H, Liu J, Yin J, Hu G, Huang B, Tu L, Liu X, Xu B, Cao Y, Guo W, Fu S
Journal of dairy science 2025 Sep;108(9):10151-10172
Journal of dairy science 2025 Sep;108(9):10151-10172
ARIH1 Promotes Preeclampsia by Inducing MFN2-Dependent Hypoxia-Triggered Mitophagy and Endoplasmic Reticulum Stress in Trophoblasts.
Liu H, Deng Y, Peng M, Nie Y, Chen J
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2025 Sep 30;39(18):e71060
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2025 Sep 30;39(18):e71060
Mechanism of Piezo1 regulating chondrocyte mitochondrial function and promoting fracture healing through β-catenin/LARS2 signaling pathway.
Zhang T, Lv H, Jia S, Wang L, Liu W, Ding K, Du X, Hou G, Hou Z, Zhang Y, Zou W, Chen W, Zhu Y
Bone research 2025 Sep 24;13(1):79
Bone research 2025 Sep 24;13(1):79
Copper-mediated MAM regulation of the NF-κB signalling pathway enhances Seneca Valley virus replication in PK-15 cells.
Wu X, Zhu S, Li M, Xu Z, Zhu L, Deng J, Deng H
Veterinary research 2025 Sep 19;56(1):175
Veterinary research 2025 Sep 19;56(1):175
Electroacupuncture Regulates Mitochondria-Endoplasmic Reticulum interactions via Fn1 in a Parkinson's Disease Model: Transcriptomic Evidence.
Lyu P, Wen F, Fu Z, Li J, Li Q, Cai X, Huang S, Qiu X, Zhang Z, Huang Y, Zhang J
Journal of integrative neuroscience 2025 Sep 18;24(9):40105
Journal of integrative neuroscience 2025 Sep 18;24(9):40105
Gestational zearalenone causes fetal intrauterine growth restriction partially through deriving ROS-Drp1 mediated placental PANoptosis.
Liu JR, Wu FN, Lin S, Chen C, Liu Y, Fan JW, Hong Q, Chen YH
Ecotoxicology and environmental safety 2025 Sep 1;302:118636
Ecotoxicology and environmental safety 2025 Sep 1;302:118636
Parkin modulates the hepatocellular carcinoma microenvironment by regulating PD-1/PD-L1 signalling.
Ye G, Sun X, Li J, Pu M, Zhang J
Journal of advanced research 2025 Oct;76:731-744
Journal of advanced research 2025 Oct;76:731-744
Porcine GWAS identifies ACOT11 as regulator for macrophage IL-1β maturation via IFNGR2 palmitoylation.
Zhang M, Liu S, Wu Z, Wang C, Zhang H, Yang J, Guo C, Dai M, Wang X, Ren W
Science China. Life sciences 2025 Oct;68(10):3037-3050
Science China. Life sciences 2025 Oct;68(10):3037-3050
PGC-1α Expands Neural Precursor Pool and Facilitates Cognitive Recovery Within AD Hippocampus Through the Regulation of Mitochondrial Dynamics.
Wang YX, Wang YJ, Pan W, Xu LF, Wang JQ, Wang H, Qian X, Zou CZ, Zhu X, Wang J
Molecular neurobiology 2025 Oct;62(10):13534-13556
Molecular neurobiology 2025 Oct;62(10):13534-13556
Skeletal Muscle PGC-1α Remodels Mitochondrial Phospholipidome but Does Not Alter Energy Efficiency for ATP Synthesis.
Karasawa T, Choi RH, Meza CA, Watanabe S, Maschek JA, Nikolova LS, Cox JE, Funai K
Journal of cachexia, sarcopenia and muscle 2025 Oct;16(5):e70090
Journal of cachexia, sarcopenia and muscle 2025 Oct;16(5):e70090
IRE1α translational suppression potentiates STING-dependent chemoresistance in pancreatic cancer.
Luo Y, Sun M, Chang L, He Z, Zhou X, Yuan Y, Sun H, Luo S, Huang J, Wu H, Liu W, Zhou Z, Mao Y, Ji Y, Liang T
Cell death & disease 2025 Oct 6;16(1):680
Cell death & disease 2025 Oct 6;16(1):680
MTCH2 modulates CPT1 activity to regulate lipid metabolism of adipocytes.
Wu C, Wang T, Ghosh A, Long F, Sharma AK, Dahlby T, Noé F, Severi I, Colleluori G, Cinti S, Giordano A, Ding L, Khandelwal R, Kostidis S, Giera M, Balazova L, Gardeux V, Abu-Nawwas L, Deplancke B, Chourasia S, Kleiner S, Hamilton BS, Alcántara JMA, Ruiz JR, Blüher M, Pekcec A, Balaz M, Gross A, Neubauer H, Wolfrum C
Nature communications 2025 Oct 3;16(1):8831
Nature communications 2025 Oct 3;16(1):8831
Luteoloside alleviates bleomycin-induced pulmonary fibrosis in mice via SIRT1-mediated protective effect against alveolar epithelial cell senescence.
Deng L, Sun B, Xia J, Zhuo W, Jiang M, Yin S, Yang F
Scientific reports 2025 Oct 29;15(1):37837
Scientific reports 2025 Oct 29;15(1):37837
FGF21-FGFR1 signaling protects against cardiac hypertrophy by regulating PINK1-mediated mitophagy pathway.
Chen L, Zheng L, Qin Y, Liu B, Zheng Y, Tong X, Dai M, Gong G
Journal of advanced research 2025 Oct 29;
Journal of advanced research 2025 Oct 29;
Mesenchymal stem cells inhibit mitochondrial fission by upregulating armadillo repeat containing 1, ameliorating oxidative stress in renal fibrosis.
Li T, Guo C, Liu Q, Jing F, Zhao M, Xiong H, Li C, Zhang W, Chen B
Stem cell research & therapy 2025 Oct 28;16(1):584
Stem cell research & therapy 2025 Oct 28;16(1):584
MAM-Mediated Mitochondrial Ca(2+) Overload and Endoplasmic Reticulum Stress Aggravates Synaptic Plasticity Impairment in Diabetic Mice.
Zhang J, Jiang J, Li H, Deng J, Dong W, Deng H
Brain sciences 2025 Oct 28;15(11)
Brain sciences 2025 Oct 28;15(11)
Atrazine-induced hippocampal neurotoxicity: Involvement of Drp1-mediated mitochondrial fission.
Yang J, Qi L, Zhang C, Ding R, Bi H, Li P, Qi Z, Niu Q, Song W, Li J
Chemico-biological interactions 2025 Oct 22;420:111676
Chemico-biological interactions 2025 Oct 22;420:111676
PTEN-L dephosphorylates Parkin and Ub Ser65 to aggravate mitophagy dysfunction in prion disease cell models.
Li X, Li J, Gou F, Dai Y, Zhao M, Wang D, Sun Z, Wen P, Wang J, Fan Q, Ma T, Wang X, Zhao D, Yang L
Life sciences 2025 Oct 15;379:123860
Life sciences 2025 Oct 15;379:123860
SAP30BP aggravates mitochondrial-related ferroptosis in diabetic cardiomyopathy by regulating MFN2-ACSL4 axis.
Zhao T, Chen C, Zhao W, Han J, Omar Jan M, Lou H, Chen Z, Liu X, Jing S
European journal of pharmacology 2025 Oct 15;1005:178046
European journal of pharmacology 2025 Oct 15;1005:178046
Role of neuroglia cell-derived microvesicles in cobalt chloride-induced mitochondrial autophagy in neurons.
Li H, Zheng F, Shao W, Yu G, Hu H, Guo Z, Wu S, Tang Y, Li H
Toxicology 2025 Nov;517:154214
Toxicology 2025 Nov;517:154214
Targeting STING alleviates pyroptosis of bladder epithelial cells and ameliorates bladder fibrosis in neurogenic bladder.
Wang R, Wang M, Chen J, Sun M, Zhao P, Zheng X, Li D, Long C, Shen L, Wei G, Wu S
Biochemical pharmacology 2025 Nov;241:117177
Biochemical pharmacology 2025 Nov;241:117177
Electroacupuncture improves motor function after ischemic stroke via regulating mitochondrial dynamics.
Li Z, Ji X, Wang X, Wang J, Lin R, Ma X, Zhang Q, Liang S
Brain research bulletin 2025 Nov;232:111599
Brain research bulletin 2025 Nov;232:111599
Baicalin alleviates oxidative stress in DF-1 cell line via the Mfn2/MAMs/Ca (2+) pathway.
Lin Z, Wang J, Li J, Zheng Y, Zheng B, Li Q, Huang X
Poultry science 2025 Nov;104(11):105818
Poultry science 2025 Nov;104(11):105818
Mfn2 Regulates Scleral Remodeling in Myopia by Maintaining Endoplasmic Reticulum Homeostasis in Scleral Fibroblasts.
Wang Y, Liu S, Huang Q, Cheng Y
Investigative ophthalmology & visual science 2025 Nov 3;66(14):40
Investigative ophthalmology & visual science 2025 Nov 3;66(14):40
Oxymatrine Alleviates Cerebral Ischemia/Reperfusion Injury By Targeting HDAC1 to Regulate Mitochondria-Related Autophagy and Oxidative Stress.
Ma CS, Han B, Liu YX, Shi CK, Li DL, Guo JF, Bai M, Meng SC, Zhang LY, Duan MY, He MT
Molecular neurobiology 2025 Nov 29;63(1):219
Molecular neurobiology 2025 Nov 29;63(1):219
CCDC141 is a Connectin/Titin and Nesprin-1 binding protein that adapts cardiomyocytes to mechanical stress.
Hanashima A, Kimoto M, Ujihara Y, Hashimoto K, Usui Y, Ohira M, Hoshino M, Uesugi K, Witt S, Labeit D, Kimura S, Murayama T, Sakurai T, Labeit S, Mohri S
Communications biology 2025 Nov 26;8(1):1693
Communications biology 2025 Nov 26;8(1):1693
TAAR1 deficiency impairs mitochondrial dynamics and synaptic integrity in the medial prefrontal cortex and associated cognition in mice.
Zhang XQ, Xiong J, Liu DN, Zhang CC, Zhang Y, Li JT, Si TM, Su YA
Translational psychiatry 2025 Nov 21;15(1):490
Translational psychiatry 2025 Nov 21;15(1):490
Renal clearable CRISPR nanosensor targeting mitochondrial DNA mutation for noninvasive monitoring of tumor progression and metastasis.
Li Y, Wu Y, Zheng Z, Wu Y, Zhang Y, Zhang J, Quan F, Zhao W, Xu R, Li Y, Gao H, Zhang K
Science advances 2025 Nov 21;11(47):eadz4594
Science advances 2025 Nov 21;11(47):eadz4594
Nrf2 alleviates excessive deposition of extracellular matrix in mammary fibrosis through TGF/Smad and ROS signals.
Kan X, Xu P, Yu M, Guo W, Cao Y, Hu G, Liu J, Fu S, Bi J
Scientific reports 2025 Nov 10;15(1):39252
Scientific reports 2025 Nov 10;15(1):39252
Cisplatin transported by COX17 induces cochlear damage by binding Myosin IIA to regulate cell pyroptosis induced by mitochondrial dysfunction.
Peng J, Tao G, Chen X, Ai Y, Lai R, Liu W, Hu B, Xu Y, Xie B, Li L
Life sciences 2025 Nov 1;380:123961
Life sciences 2025 Nov 1;380:123961
OAC1 improves mitofusin 2 expression to alleviate neuronal injury following experimental ischemic stroke.
Wang Y, Chen K, Xu B, Wang H, Wang H, Lü T
The Korean journal of physiology & pharmacology : official journal of the Korean Physiological Society and the Korean Society of Pharmacology 2025 Nov 1;29(6):741-753
The Korean journal of physiology & pharmacology : official journal of the Korean Physiological Society and the Korean Society of Pharmacology 2025 Nov 1;29(6):741-753
Effect of disruption of mitochondrial and endoplasmic reticulum calcium homeostasis on neurites in hydrogen peroxide- and ionomycin-treated cells.
Hoga K, Wakuzawa M, Nakamura T, Kato Y, Fukui K
Journal of clinical biochemistry and nutrition 2025 May;76(3):253-263
Journal of clinical biochemistry and nutrition 2025 May;76(3):253-263
Ginsenoside Rg5 alleviates radiation-induced acute lung vascular endothelium injury by reducing mitochondrial apoptosis via Sirt1.
Li C, Zhao B, Xiong J, Li L, Pang D, Unger K, Jung M, Lyu J, Kuang H, Liang L, Li T, Chen L, Bai H
Journal of ginseng research 2025 May;49(3):260-270
Journal of ginseng research 2025 May;49(3):260-270
Protective effect of astragaloside IV against zinc oxide nanoparticles induced human neuroblastoma SH-SY5Y cell death: a focus on mitochondrial quality control.
Wang L, Zhang L, Yun Y, Liang T, Yan C, Mao Z, Zhang J, Liu B, Zhang J, Liang T
Molecular and cellular biochemistry 2025 May;480(5):3079-3095
Molecular and cellular biochemistry 2025 May;480(5):3079-3095
Cardioprotective effects of Dendrobium officinale polysaccharides on thiacloprid-induced cardiac injury via modulating mitochondrial dynamics.
Han B, Tian J, Li J, Chen Y, Liu N, Ma Y, Wang C, Guo X, Liu Y, Zhang Z
International journal of biological macromolecules 2025 May;309(Pt 2):142497
International journal of biological macromolecules 2025 May;309(Pt 2):142497
FTO-mediated m6A modification elevates the MFN2 mRNA stability to suppress ovarian granulosa cell senescence.
Li Q, Shen H, Liu A, Yu L, Wang L, Zhang X
International journal of biological macromolecules 2025 May;307(Pt 4):142181
International journal of biological macromolecules 2025 May;307(Pt 4):142181
SIRT5 modulates mitochondria function via mitophagy and antioxidant mechanisms to facilitate oocyte maturation in mice.
Yan JJ, Wang YY, Shi ZY, Ding YY, Wen HQ, Wu MP, Sun SC, Cai YF, Zhang Y
International journal of biological macromolecules 2025 May;306(Pt 2):141488
International journal of biological macromolecules 2025 May;306(Pt 2):141488
Empagliflozin attenuates renal damage in diabetic nephropathy by modulating mitochondrial quality control via Prdx3-PINK1 pathway.
Guo C, Zhang T, Du L, Yu K, Zeng S, Li M, Chi Y, Li Y
Biochemical pharmacology 2025 May;235:116821
Biochemical pharmacology 2025 May;235:116821
Salidroside alleviates doxorubicin-induced hepatotoxicity via Sestrin2/AMPK-mediated pyroptotic inhibition.
Wang N, Gao Z, Zhan H, Jing L, Meng F, Chen M
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 2025 May;199:115335
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 2025 May;199:115335
Lycium barbarum glycopeptide attenuates intracerebral hemorrhage-induced inflammation and oxidative stress via activation of the Sirt3 signaling pathway.
Ma CS, Han B, Meng SC, Bai M, Yi WJ, Zhang LY, Duan MY, Wang YJ, He MT
International immunopharmacology 2025 May 8;154:114518
International immunopharmacology 2025 May 8;154:114518
Mechanistic study of modulating mitochondrial fission and fusion to ameliorate neuropathic pain in mice.
Xie L, Cao J, Xu Y, Yang Q, Chang W, Song L, Sun Y
Scientific reports 2025 May 4;15(1):15571
Scientific reports 2025 May 4;15(1):15571
Overexpression of c-Myc triggers p62 aggregation-mediated mitochondrial mitophagy in cabozantinib resistance of hepatocellular carcinoma.
Yang K, Zhang X, Yang K, Liu S, Zhang J, Fu Y, Liu T, Wu K, Li J, Liu C, Huang Q, Qu K
Molecular medicine (Cambridge, Mass.) 2025 May 27;31(1):209
Molecular medicine (Cambridge, Mass.) 2025 May 27;31(1):209
Mitochondrial aldehyde dehydrogenase restores the migratory capacity inhibited by high glucose-induced hyperosmolality.
Huang CC, Chen YL, Chien CL
Scientific reports 2025 May 22;15(1):17741
Scientific reports 2025 May 22;15(1):17741
Cardiomyocyte specific CD38 deletion protects heart from acute myocardial infarction by activating Sirt3 signaling pathway.
Wen K, Zhang YT, Zhao QH, Li Q, Zhao JL, Ding Q, Xiao YF, Guan XH, Jiang MX, Qian YS, Tian XL, Wang LF, Deng KY, Xin HB
Scientific reports 2025 May 17;15(1):17165
Scientific reports 2025 May 17;15(1):17165
Leucine 7 is a key residue for mutant huntingtin-induced mitochondrial pathology and neurotoxicity in Huntington's disease.
Zhang S, Wang S, Yang Z, Li Y, Li J, Chen X, Yao H, Zheng Z, Guo X
The Journal of biological chemistry 2025 Mar;301(3):108297
The Journal of biological chemistry 2025 Mar;301(3):108297
Procyanidin B2 alleviates damage to mouse testicular tissue after freezing by inhibiting oxidative stress and apoptosis.
Cao G, Li C, Zhang J, Deng L, Li R, Xu C
Cryobiology 2025 Mar;118:105196
Cryobiology 2025 Mar;118:105196
Impact of POU3F4 mutation on cochlear development and auditory function.
Dang J, Bian P, Chen C, Chen C, Shan W, Cai L, Li Y, Tan H, Xu B, Guan M, Guo Y
Cell communication and signaling : CCS 2025 Mar 5;23(1):121
Cell communication and signaling : CCS 2025 Mar 5;23(1):121
S-nitrosylation of peroxiredoxin 2 exacerbates hyperuricemia-induced renal injury through regulation of mitochondrial homeostasis.
Han F, Dong Y, Liu Q, Song L, Guo H, Zhu L, Sun B, Zhao W, Chen L
Free radical biology & medicine 2025 Mar 16;230:66-78
Free radical biology & medicine 2025 Mar 16;230:66-78
Neurotoxicity of Realgar: Crosstalk Between UBXD8-DRP1-Regulated Mitochondrial Fission and PINK1-Parkin-Mediated Mitophagy.
Feng R, Liu J, Yao T, Yang Z, Jiang H
Molecular neurobiology 2025 Jun;62(6):7041-7053
Molecular neurobiology 2025 Jun;62(6):7041-7053
Piwei Peiyuan Prescription Attenuates the Progression of Chronic Atrophic Gastritis by Eliciting MAPK10-Mediated Mitochondrial Autophagy.
Zhang Y, Wu Y, Pei B, Sun Q, Zhang C, Yang Q, Jin Y, Wu J, Li X
Cell biology international 2025 Jun;49(6):692-708
Cell biology international 2025 Jun;49(6):692-708
Autophagy receptor optineurin promotes spring viremia of carp virus replication via mitophagy and innate immune pathways in Cyprinus carpio.
Zhang Y, Li C, Zhang M, Qi S, Kong X
International journal of biological macromolecules 2025 Jun;315(Pt 1):144309
International journal of biological macromolecules 2025 Jun;315(Pt 1):144309
Lycium barbarum polysaccharide alleviate cadmium-induced mitochondrial dysfunction mediated pyroptosis in duck liver.
Song J, Luo X, Xiong L, Li S, Chen Y, Liu W, Yuan Y, Ma Y, Bian J, Liu Z, Zou H
International journal of biological macromolecules 2025 Jun;311(Pt 4):143989
International journal of biological macromolecules 2025 Jun;311(Pt 4):143989
Triptolide inhibits migration and viability, and promotes apoptosis by targeting the PI3K/Akt signaling pathway via upregulation of miR‑125a‑5p in SW1353 human chondrosarcoma cells.
Liang C, Zhuoer Z, Yuan L, Bing Z
Molecular medicine reports 2025 Jun;31(6)
Molecular medicine reports 2025 Jun;31(6)
Salmonella Typhimurium persistently infects host via its effector SseJ-induced PHB2-mediated mitophagy.
Sun D, Gou H, Zhang Y, Li J, Dai C, Shen H, Chen K, Wang Y, Pan P, Zhu T, Xu C, Shan T, Liao M, Zhang J
Autophagy 2025 Jun;21(6):1228-1244
Autophagy 2025 Jun;21(6):1228-1244
Astragaloside IV Relieves Mitochondrial Oxidative Stress Damage and Dysfunction in Diabetic Mice Endothelial Progenitor Cells by Regulating the GSK-3β/Nrf2 Axis.
Zou X, Liu X, Qu W, Zhang X, Zou Y, Lin X, Hu W, Gao R, He Y, Zhou S, Huang Y, Xiong W
Applied biochemistry and biotechnology 2025 Jun;197(6):3964-3981
Applied biochemistry and biotechnology 2025 Jun;197(6):3964-3981
Schisandrin B regulates mitochondrial dynamics via AKT1 activation and mitochondrial targeting to ameliorate renal ischemia-reperfusion injury.
Xu C, Wang H, Wang H, Man J, Deng Y, Li Y, Cheng K, Niu J, Gui H, Fu S, Yang L
Phytomedicine : international journal of phytotherapy and phytopharmacology 2025 Jun;141:156672
Phytomedicine : international journal of phytotherapy and phytopharmacology 2025 Jun;141:156672
Injectable pH Responsive Conductive Hydrogel for Intelligent Delivery of Metformin and Exosomes to Enhance Cardiac Repair after Myocardial Ischemia-Reperfusion Injury.
Cheng N, Luo Q, Yang Y, Shao N, Nie T, Deng X, Chen J, Zhang S, Huang Y, Hu K, Luo L, Xiao Z
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2025 Jun;12(24):e2410590
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2025 Jun;12(24):e2410590
Diallyl Trisulfide From Garlic Regulates RAB18 Phase Separation to Inhibit Lipophagy and Induce Cuproptosis in Hepatic Stellate Cells for Antifibrotic Effects.
Tian H, Sun S, Qiu X, Wang J, Gao Y, Chen J, Han X, Bao Z, Guo X, Sun Y, Lin Y, Hu M, Zhang F, Zhang Z, Wang F, Zheng S, Shao J
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2025 Jun;12(21):e2415325
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2025 Jun;12(21):e2415325
Intratracheal Administration of Polystyrene Micro(nano)plastics with a Mixed Particle Size Promote Pulmonary Fibrosis in Rats by Activating TGF-β1 Signaling and Destabilizing Mitochondrial Dynamics and Mitophagy in a Dose- and Time-Dependent Manner.
Xia S, Yuan C, Long W, Wu Z, Li X, Wang N, Gao M, Li Z, Li P, Liu P, Qu X, Sun L
Toxics 2025 Jun 9;13(6)
Toxics 2025 Jun 9;13(6)
PINK1 affects mitochondrial oxidative phosphorylation by regulating MFN2 to alleviate diabetic kidney disease.
Pei X, Liu J, Wei Y, Zhu Y, Li Y, Wang Q, Zhuang L, Jin G
International immunopharmacology 2025 Jun 5;157:114786
International immunopharmacology 2025 Jun 5;157:114786
STING-mediated mitochondrial DNA release exacerbates PANoptosis in liver ischemia reperfusion injury.
Wu C, Miao H, Yi Z, Jia H, Huang A, Zhang H, Liu Z, Sun X, Zheng Y, Gao L, Ma S
International immunopharmacology 2025 Jun 5;157:114778
International immunopharmacology 2025 Jun 5;157:114778
O-GlcNAcylation-mediated endothelial metabolic memory contributes to cardiac damage via small extracellular vesicles.
Ding M, Shi R, Du Y, Chang P, Gao T, De D, Chen Y, Li M, Li J, Li K, Cheng S, Gu X, Li J, Zhang S, Feng N, Liu J, Jia M, Fan R, Pei J, Gao C, Fu F
Cell metabolism 2025 Jun 3;37(6):1344-1363.e6
Cell metabolism 2025 Jun 3;37(6):1344-1363.e6
Reduced NRF2/Mfn2 activity promotes endoplasmic reticulum stress and senescence in adipose-derived mesenchymal stem cells in hypertrophic obese mice.
Fang J
World journal of stem cells 2025 Jun 26;17(6):104367
World journal of stem cells 2025 Jun 26;17(6):104367
Ginsenoside Rh2 Exerts a Therapeutic Effect against Myocardial Infarction via Promoting Angiogenesis and Mitochondrial Bioenergetics.
Duan Z, Yuan B, Li H, Yang J, Xiao X, Wei K
Journal of agricultural and food chemistry 2025 Jun 18;73(24):15056-15066
Journal of agricultural and food chemistry 2025 Jun 18;73(24):15056-15066
Acetaldehyde dehydrogenase 2 attenuates lipopolysaccharide -induced endothelial barrier damage by inhibiting mitochondrial fission in sepsis-associated encephalopathy.
Wang S, Liu Z, Li R, Wang L, Wu Y, Zhang W, Yu Y
European journal of pharmacology 2025 Jun 15;997:177468
European journal of pharmacology 2025 Jun 15;997:177468
Endosomal RFFL ubiquitin ligase regulates mitochondrial morphology by targeting mitofusin 2.
Narendradev ND, Ravindran R, Jain P, Chaudhary S, Velikkakath AKG, Sudharman A, Janardhanan A, Nag TC, Yadav SC, Srinivasula SM
Journal of cell science 2025 Jun 15;138(12)
Journal of cell science 2025 Jun 15;138(12)
Bavachin ameliorates cisplatin-induced nephrotoxicity by enhancing mitochondrial β-oxidation and lipid metabolism through MFN2.
Luo S, Yang M, Jiang N, Li C, Liu Y, Sun L
Molecular medicine (Cambridge, Mass.) 2025 Jun 11;31(1):234
Molecular medicine (Cambridge, Mass.) 2025 Jun 11;31(1):234
The role of mitochondrial dysfunction in the protective effect of ginger derived extracellular vesicles on hepatic stellate cells against cytotoxicity.
Yang J, Yang Y, Zhang X, Qin Y, Sato T, Qing S, Wang Y, Ye X, Xu M, Liu Y, He Q, Zheng Y
Molecular and cellular biochemistry 2025 Jul;480(7):4297-4309
Molecular and cellular biochemistry 2025 Jul;480(7):4297-4309
Norepinephrine Attenuates Benzalkonium Chloride-Induced Dry Eye Disease by Regulating the PINK1/Parkin Mitophagy Pathway.
Zhao H, Wang W, Yang Y, Feng C, Lin T, Gong L
Ocular immunology and inflammation 2025 Jul;33(5):766-780
Ocular immunology and inflammation 2025 Jul;33(5):766-780
Downregulation of Mfn2 Contributes to Chronic Postsurgical Pain via Inducing the Pyroptosis of GABAergic Neurons in the Spinal Cord.
Hu Y, He X, Zang H, Chen Y, Li L, Liu T, Wan L, Zhu C, Yao W
CNS neuroscience & therapeutics 2025 Jul;31(7):e70508
CNS neuroscience & therapeutics 2025 Jul;31(7):e70508
Extremely low-frequency electromagnetic field (ELF-EMF) enhances mitochondrial energy production in NARP cybrids.
Ito M, Huang Z, Nomura K, Teranishi M, Zhao F, Mino H, Yoneda M, Tanaka M, Ohno K
Scientific reports 2025 Jul 8;15(1):24369
Scientific reports 2025 Jul 8;15(1):24369
Increased ROS levels activate AMPK-ULK1-mediated mitophagy to promote pseudorabies virus replication.
Zhao Y, Qi X, Zhu Z, Wang W, Wen W, Li X
Veterinary research 2025 Jul 21;56(1):156
Veterinary research 2025 Jul 21;56(1):156
S-COS-Se mitigates cadmium-induced oxidative stress, inflammation, and immunotoxicity by restoring immune balance and inhibiting mitochondria-pyroptosis crosstalk.
Zheng H, Dong W, Qiu H, Gao S, Hou L, Dong J, Zhao P, Chen F
Ecotoxicology and environmental safety 2025 Jul 15;300:118462
Ecotoxicology and environmental safety 2025 Jul 15;300:118462
Tang Bi formula alleviates diabetic sciatic neuropathy via AMPK/PGC-1α/MFN2 pathway activation.
Yang C, Yu H, Zhou L, Su H, Li X, Qi W, Lian F
Scientific reports 2025 Jul 11;15(1):25069
Scientific reports 2025 Jul 11;15(1):25069
Drp1-Dependent Mitochondrial Fission Contributes to Lactic Acid-Induced Chicken Cardiomyocyte Damage.
Hu D, Cui Y, Hou X, Wang X, Shen Z, Pang H, Ge Y, Ning H
Journal of biochemical and molecular toxicology 2025 Jan;39(1):e70128
Journal of biochemical and molecular toxicology 2025 Jan;39(1):e70128
SENP1 prevents high fat diet-induced non-alcoholic fatty liver diseases by regulating mitochondrial dynamics.
Zeng W, Wang L, Wang C, Xiong X, Huang Q, Chen S, Liu C, Liu W, Wang Y, Huang Q
Biochimica et biophysica acta. Molecular basis of disease 2025 Jan;1871(1):167527
Biochimica et biophysica acta. Molecular basis of disease 2025 Jan;1871(1):167527
Hydrogen restores central tryptophan and metabolite levels and maintains mitochondrial homeostasis to protect rats from chronic mild unpredictable stress damage.
Li J, Hao G, Yan Y, Li M, Li G, Lu Z, Sun Z, Chen Y, Liu H, Zhao Y, Wu M, Bao X, Wang Y, Li Y
Neurochemistry international 2025 Jan;182:105914
Neurochemistry international 2025 Jan;182:105914
9-PAHSA ameliorates microvascular damage during cardiac ischaemia/reperfusion injury by promoting LKB1/AMPK/ULK1-mediated autophagy-dependent STING degradation.
Liu W, Hu J, Wang Y, Gan T, Ding Y, Wang X, Xu Q, Xiong J, Xiong N, Lu S, Wang Y, Wang Z
Phytomedicine : international journal of phytotherapy and phytopharmacology 2025 Jan;136:156241
Phytomedicine : international journal of phytotherapy and phytopharmacology 2025 Jan;136:156241
TNFα-reliant FSP1 up-regulation promotes intervertebral disc degeneration via caspase 3-dependent apoptosis.
Qiu C, Cheng L, Di D, Xiang Z, Wang C, Li J, Xiong Y, Li M, Liu J, Zhou J, Liu T, Wang X, Luo D, Wang X, Li S, Wang H, Wang X, Zhao Y, Liu X, Wang L
Genes & diseases 2025 Jan;12(1):101251
Genes & diseases 2025 Jan;12(1):101251
Rostellularia procumbens (L) Nees. extract attenuates adriamycin-induced nephropathy by maintaining mitochondrial dynamics balance via SIRT1/PGC-1α signaling pathway activation.
Ai Z, Yuan D, Dong R, Zhou S, Cao J
Journal of ethnopharmacology 2025 Jan 31;340:119297
Journal of ethnopharmacology 2025 Jan 31;340:119297
Rg1 improves Alzheimer's disease by regulating mitochondrial dynamics mediated by the AMPK/Drp1 signaling pathway.
Zhang Y, Liu S, Cao D, Zhao M, Lu H, Wang P
Journal of ethnopharmacology 2025 Jan 31;340:119285
Journal of ethnopharmacology 2025 Jan 31;340:119285
Po-Ge-Jiu-Xin decoction alleviate sepsis-induced cardiomyopathy via regulating phosphatase and tensin homolog-induced putative kinase 1 /parkin-mediated mitophagy.
Wang Z, Wang Y, Dong C, Miao K, Jiang B, Zhou D, Dong K, Wang Y, Zhang Z
Journal of ethnopharmacology 2025 Jan 30;337(Pt 3):118952
Journal of ethnopharmacology 2025 Jan 30;337(Pt 3):118952
Study on the role of Dihuang Yinzi in regulating the AMPK/SIRT1/PGC-1α pathway to promote mitochondrial biogenesis and improve Alzheimer's disease.
Zhu C, Zhang Z, Zhu Y, Du Y, Han C, Zhao Q, Li Q, Hou J, Zhang J, He W, Qin Y
Journal of ethnopharmacology 2025 Jan 30;337(Pt 2):118859
Journal of ethnopharmacology 2025 Jan 30;337(Pt 2):118859
Dapagliflozin and Sirtuin-1 interaction and mechanism for ameliorating atrial fibrillation in a streptozotocin-induced rodent diabetic model.
Lee WC, Lin YW, Shih JY, Chen ZC, Wu NC, Chang WT, Liu PY
Biomolecules & biomedicine 2025 Jan 30;25(3):608-622
Biomolecules & biomedicine 2025 Jan 30;25(3):608-622
Isovitexin targets SIRT3 to prevent steroid-induced osteonecrosis of the femoral head by modulating mitophagy-mediated ferroptosis.
Fan Y, Chen Z, Wang H, Jiang M, Lu H, Wei Y, Hu Y, Mo L, Liu Y, Zhou C, He W, Chen Z
Bone research 2025 Jan 26;13(1):18
Bone research 2025 Jan 26;13(1):18
Engineered hypoxia-responsive albumin nanoparticles mediating mitophagy regulation for cancer therapy.
Wang W, Yao SY, Luo J, Ding C, Huang Q, Yang Y, Shi Z, Lin J, Pan YC, Zeng X, Guo DS, Chen H
Nature communications 2025 Jan 11;16(1):596
Nature communications 2025 Jan 11;16(1):596
Ginsenoside Rb3 Promotes Opa1-Mediated Regenerative Neurogenesis via Activating the Ido1 Pathway in Ischemic Stroke.
Wang L, Qin N, Gao S, Zhu T
Phytotherapy research : PTR 2025 Feb;39(2):564-580
Phytotherapy research : PTR 2025 Feb;39(2):564-580
Role of MFN2 in bovine embryonic development and the mitigation of ER stress.
Shi SM, Hu B, Chi ZC, Qu LY, Liu LY, He YY, Jia GL, Li JH, Kong I, Jin YX, Yu XF
Animal reproduction science 2025 Feb;273:107664
Animal reproduction science 2025 Feb;273:107664
Chronic alcohol consumption exacerbates ischemia-associated skeletal muscle mitochondrial dysfunction in a murine model of peripheral artery disease.
Fletcher E, Miserlis D, Papoutsi E, Steiner JL, Gordon B, Haynatzki G, Pacher P, Koutakis P
Biochimica et biophysica acta. Molecular basis of disease 2025 Feb;1871(2):167584
Biochimica et biophysica acta. Molecular basis of disease 2025 Feb;1871(2):167584
HIV-1 gp120 Interactions with Nicotine Modulate Mitochondrial Network Properties and Amyloid Release in Microglia.
Graur A, Erickson N, Sinclair P, Nusir A, Kabbani N
Neurochemical research 2025 Feb 24;50(2):103
Neurochemical research 2025 Feb 24;50(2):103
Nrf2 activator tertiary butylhydroquinone enhances neural stem cell differentiation and implantation in Alzheimer's disease by boosting mitochondrial function.
Lin L, Li J, Yu Z, He J, Li Y, Jiang J, Xia Y
Brain research 2025 Feb 15;1849:149341
Brain research 2025 Feb 15;1849:149341
Dexmedetomidine ameliorates hepatic ischemia reperfusion injury via modulating SIRT3 mediated mitochondrial quality control.
Ning X, Tang J, Li X, Wang J, Zhai F, Jiang C, Zhang S
Scientific reports 2025 Feb 15;15(1):5630
Scientific reports 2025 Feb 15;15(1):5630
Buyang Huanwu Decoction restores the balance of mitochondrial dynamics after cerebral ischemia-reperfusion through calcium overload reduction by the PKCε-Nampt-Sirt5 axis.
Liu Z, Yin M, Li J, Wang J, Jin X, Zhou X, Gao W
Journal of ethnopharmacology 2025 Feb 10;338(Pt 3):119003
Journal of ethnopharmacology 2025 Feb 10;338(Pt 3):119003
PANAXADIOL SAPONIN ALLEVIATES LPS-INDUCED CARDIOMYOPATHY SIMILAR TO DEXAMETHASONE VIA IMPROVING MITOCHONDRIAL QUALITY CONTROL.
Yang Z, Gao Y, Li D, Zhao L, Du Y
Shock (Augusta, Ga.) 2025 Feb 1;63(2):282-291
Shock (Augusta, Ga.) 2025 Feb 1;63(2):282-291
C3a/C3aR axis is involved in diabetic kidney injury by regulating podocyte mitophagy in diabetic nephropathy.
Weng M, Wu X, Rao S, Nie K, You D, Zheng T, Lin E, Zheng J, Cui J, Wan J
International journal of molecular medicine 2025 Dec;56(6)
International journal of molecular medicine 2025 Dec;56(6)
RAB3GAP2 silencing alleviates oxidative stress in cataracts by enhancing Mfn2-mediated mitochondrial autophagy by activating JNK/STAT3.
Huang Y, Liu Q, Chen L, Tan X, Zeng D, Zhang Y, Qin J, Zeng F, Wei X, Zhong Q, Zhang J, Yuan D
International journal of biological macromolecules 2025 Dec;334(Pt 2):149102
International journal of biological macromolecules 2025 Dec;334(Pt 2):149102
Cytosolic TOP3α facilitates mitochondrial DNA sensing by cGAS.
Cai D, Chen C, Meekrathok P, Zeng W, Wang Z, Peng Z, Mo Y, Xu X, Wang J, Qiu J
EMBO reports 2025 Dec;26(23):5959-5981
EMBO reports 2025 Dec;26(23):5959-5981
ER stress sensor PERK drives ferroptosis by disrupting MAMs-mediated mitochondrial homeostasis and promoting mtROS accumulation in acute myocardial infarction.
Tao X, Zhang Y, Pang J, Liao Z, Chen G, Zhong X, Cao X, Lin Y, Guan D, Tian Y, Hao L, Zhao R, Cao Z
Pharmacological research 2025 Dec;222:108029
Pharmacological research 2025 Dec;222:108029
ATP1B4 as a candidate upstream regulator of muscle atrophy in diabetic sarcopenia via PI3K/AKT/mTOR-mediated autophagy.
Duan T, Jia S, Zhou D, Zhao L
The international journal of biochemistry & cell biology 2025 Dec;189:106869
The international journal of biochemistry & cell biology 2025 Dec;189:106869
Hispolon reduces mitochondrial dysfunction and improves fibrosis of diabetes nephropathy by activating AMPK signal and inhibiting mPTP opening.
Wang Y, Danis A, Wang X, Ren J, Ma T, Wang R
Cellular signalling 2025 Dec;136:112130
Cellular signalling 2025 Dec;136:112130
The binding of PCBP2 to IGF2 mRNA restores mitochondrial function in granulosa cells to ameliorate ovarian function in premature ovarian insufficiency mice.
Chen Y, Pan X, Tang J, Liu Z, Luo M, Wen Y
Cellular signalling 2025 Dec;136:112103
Cellular signalling 2025 Dec;136:112103
KDM6B induces demethylation of H3K27me3 in MFN1 to modulate aberrant mitophagy in sepsis-induced acute lung injury.
Deng H, Zhu S, Song X, Guo Y, Ding X
Scientific reports 2025 Dec 8;15(1):43339
Scientific reports 2025 Dec 8;15(1):43339
Multi-Omics Analysis Reveals Distinct Lipid Remodelling and Mitochondrial Stress in SH-SY5Y Cells Modelling Parkinson's Disease.
Wang S, Ni Z, Wang G, Zhang J, Tan Y, Hong E, Wang Y, Chen H, Hou H, Hu Q
Metabolites 2025 Dec 4;15(12)
Metabolites 2025 Dec 4;15(12)
Gpr109a alleviates mammary fibrosis via PPARγ-mediated reduction of ROS and mitochondrial damage.
Bi J, He D, Li F, Xu P, Huang Y, Guo W, Fu S, Kan X, Li Y
International immunopharmacology 2025 Dec 3;166:115603
International immunopharmacology 2025 Dec 3;166:115603
Schwann cell Lrp1 deletion drives trigeminal neuron sensitization and orofacial pain by modulating mitochondrial function and TRPV1/TRPA1 activity.
Gong Z, Zhang M, Liu N, Asam K, Martellucci S, Aouizerat B, Campana W, Ye Y
The journal of headache and pain 2025 Dec 22;26(1):290
The journal of headache and pain 2025 Dec 22;26(1):290
NDUFAB1 promotes hepatocellular carcinoma progression by disrupting mitochondrial homeostasis and mitophagy pathway.
Yao Z, Tan X, Cui H, Liang H, Zhong A, Man Y, Yi T, Zhang Z, Guo X, Tan S, Zhu X
International immunopharmacology 2025 Dec 10;167:115664
International immunopharmacology 2025 Dec 10;167:115664
FUNDC1-dependent mitochondrial-ER membranes mediate mitochondrial dysfunction and melanocyte damage under oxidative stress.
Ma J, Yuan M, Guo S, Gao T, Li C, Liu L
Free radical biology & medicine 2025 Dec 1;240:108-123
Free radical biology & medicine 2025 Dec 1;240:108-123
Leber's hereditary optic neuropathy-associated ND1 3733G>C mutation ameliorates the mitochondrial quality control and cellular homeostasis.
Yasheng M, Ji Y, He Y, Yi Q, Zhang H, Shan W, Wang K, Zhang J, Li Y, Meng F, Zhang M, Mo JQ, Wei S, Guan MX
The Journal of biological chemistry 2025 Aug;301(8):110464
The Journal of biological chemistry 2025 Aug;301(8):110464
The low-density lipoprotein receptor-related protein-1 (LRP1) in Schwann cells controls mitochondria homeostasis in peripheral nerves.
Martellucci S, Heredia M, Wang Z, Whisenant T, Strickland DK, Sanchez R, Arai T, Zhang M, Wang H, Gong Z, Asam K, Aouizerat BE, Pekkurnaz G, Ye Y, Campana WM
Progress in neurobiology 2025 Aug;251:102796
Progress in neurobiology 2025 Aug;251:102796
Mn(2)O(3) NPs-induced liver injury is potentially associated with gut microbiota dysbiosis in broiler chicken.
Li Y, Yi J, Liu K, Liu X, Yangzom C, Pan J, Iqbal M, Hu L, Tang Z, Li Y, Zhang H
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 2025 Aug;202:115487
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 2025 Aug;202:115487
Decoding the role of nucleic acid binding protein 2 in lipid dysregulation and hepatocellular carcinoma progression through LKB1-mediated mitochondrial dysfunction.
Dai C, Tong Y, Bai N, Xu N, Zhao X, Zhou L, Tang Z, Liu M, Xu B, Liu X, Chen Y, Lin Z, Li J, Bian S, Zheng W
Cellular signalling 2025 Aug;132:111820
Cellular signalling 2025 Aug;132:111820
Melatonin mitigates arsenic and fluoride-induced cardiotoxicity in chickens by maintaining mitochondrial homeostasis.
Yuan X, Wen B, Hu X, Yang M, Han L, Zhao S, Zhang J, Ma Y
Poultry science 2025 Aug;104(8):105325
Poultry science 2025 Aug;104(8):105325
Umbilical Cord Mesenchymal Stem Cell-Derived Extracellular Vesicles Enhance Chondrocyte Function by Reducing Oxidative Stress in Chondrocytes.
Wu CW, Huang YH, Shao PL, Chang LH, Lu CC, Chen CH, Fu YC, Ho ML, Chang JK, Wu SC
International journal of molecular sciences 2025 Aug 8;26(16)
International journal of molecular sciences 2025 Aug 8;26(16)
Targeting Wnt/beta-catenin signaling to attenuate short-chain chlorinated paraffins-triggered hepatocyte mitochondrial fission and subsequent pyroptosis.
Xiao J, Huang D, Wang F, Gan L, Zhang W, Zhang F, Tang J, Shen Z, Jiang M, Egbobe JO, Shao J, Wang X, Zhang Y, Ju L, Zhao X
International immunopharmacology 2025 Aug 28;161:115102
International immunopharmacology 2025 Aug 28;161:115102
SIRT1 and its SUMOylation attenuate hyperoxia-induced lung injury by improving mitochondrial biogenesis and fusion.
Yang K, Zheng Q, Luo M, Zhang R, Zhao S, Kang L, Lei X, Dong W
Free radical biology & medicine 2025 Aug 16;236:98-115
Free radical biology & medicine 2025 Aug 16;236:98-115
PGAM5 aggravated doxorubicin-induced cardiotoxicity by disturbing mitochondrial dynamics and exacerbating cardiomyocytes apoptosis.
He W, Wang J, He W, Zeng L, Zhao R, Qiu K, Tong G, Sun Z, He P
Free radical biology & medicine 2025 Aug 1;235:95-108
Free radical biology & medicine 2025 Aug 1;235:95-108
O-GlcNAcylation of hexokinase 2 modulates mitochondrial dynamics and enhances the progression of lung cancer.
Panpan SI, Wei GE, Kaiming WU, Zhang R
Molecular and cellular biochemistry 2025 Apr;480(4):2633-2643
Molecular and cellular biochemistry 2025 Apr;480(4):2633-2643
Dietary salt promotes cognitive impairment through repression of SIRT3/PINK1-mediated mitophagy and fission.
Fan H, Yuan M, Wang S, Yang X, Shu L, Pu Y, Zou Q, Zhang X, Wang C, Cai Z
Molecular and cellular biochemistry 2025 Apr;480(4):2345-2360
Molecular and cellular biochemistry 2025 Apr;480(4):2345-2360
Schisandrin B Improves Mitochondrial Function and Inhibits HT22 Cell Apoptosis by Regulating Sirt3 Protein.
Hu F, Tong S, Xu H
The Journal of membrane biology 2025 Apr;258(2):123-133
The Journal of membrane biology 2025 Apr;258(2):123-133
Long term exposure to multiple environmental stressors induces mitochondrial dynamics imbalance in testis: Insights from metabolomics and transcriptomics.
Jiang S, Nong T, Yu T, Qin Z, Huang J, Yin Z, Luo S, Lai Y, Jin J
Environment international 2025 Apr;198:109390
Environment international 2025 Apr;198:109390
Inhibition of USP30 Promotes Mitophagy by Regulating Ubiquitination of MFN2 by Parkin to Attenuate Early Brain Injury After SAH.
Liu Y, Yao C, Sheng B, Zhi S, Chen X, Ding P, Zhang J, Tao Z, Li W, Zhuang Z, Mao J, Peng Z, Yan H, Jin W
Translational stroke research 2025 Apr;16(2):448-466
Translational stroke research 2025 Apr;16(2):448-466
Evolocumab attenuates myocardial ischemia/reperfusion injury by blocking PCSK9/LIAS-mediated cuproptosis of cardiomyocytes.
Li ZZ, Guo L, An YL, Yu WJ, Shi DY, Lin QY, Zhang B
Basic research in cardiology 2025 Apr;120(2):301-320
Basic research in cardiology 2025 Apr;120(2):301-320
Epimedii Folium and Ligustri Lucidi Fructus synergistically delay renal aging through AMPK/ULK1/Bcl2L13-mediated mitophagy.
Long Y, Li Y, Ma Z, Xie Y, Zhao H, Zhang M, Liu R
Journal of ethnopharmacology 2025 Apr 25;346:119668
Journal of ethnopharmacology 2025 Apr 25;346:119668
Mitofusin-Mediated Mitochondrial Fusion Inhibits Pseudorabies Virus Infection in Porcine Cells.
Xu X, Zhao Y, Zhu Z, Wen W, Li X
Veterinary sciences 2025 Apr 15;12(4)
Veterinary sciences 2025 Apr 15;12(4)
Effect of 1-DNJ on Oxidative Stress-Induced Apoptosis in Porcine Ovarian GCs Through Modulation of the PERK-ATF4/MFN2 Signaling Pathway.
Xing W, Li M, Wang B, Huo L, Tian W, Ge F, Shen M, Sun L, Liu J, Yu S
Antioxidants (Basel, Switzerland) 2025 Apr 11;14(4)
Antioxidants (Basel, Switzerland) 2025 Apr 11;14(4)
ARMC1 partitions between distinct complexes and assembles MIRO with MTFR to control mitochondrial distribution.
McKenna MJ, Kraus F, Coelho JPL, Vasandani M, Zhang J, Adams BM, Paulo JA, Harper JW, Shao S
Science advances 2025 Apr 11;11(15):eadu5091
Science advances 2025 Apr 11;11(15):eadu5091
Asparagine transporter supports macrophage inflammation via histone phosphorylation.
Wang C, Ye Y, Zhao M, Chen Q, Liu B, Ren W
Science advances 2025 Apr 11;11(15):eads3506
Science advances 2025 Apr 11;11(15):eads3506
PTPLAD1 Regulates PHB-Raf Interaction to Orchestrate Epithelial-Mesenchymal and Mitofusion-Fission Transitions in Colorectal Cancer.
Huang ZJ, Li YJ, Yang J, Huang L, Zhao Q, Lu YF, Hu Y, Zhang WX, Liang JZ, Pan J, Pan YL, He QY, Wang Y
International journal of biological sciences 2024;20(6):2202-2218
International journal of biological sciences 2024;20(6):2202-2218
Loss of MTX2 causes mitochondrial dysfunction, podocyte injury, nephrotic proteinuria and glomerulopathy in mice and patients.
Li T, Bao Y, Xia Y, Meng H, Zhou C, Huang L, Wang X, Lai EY, Jiang P, Mao J
International journal of biological sciences 2024;20(3):937-952
International journal of biological sciences 2024;20(3):937-952
Circular RNA TAF4B targeting MFN2 accelerates cell growth in bladder cancer through p27 depression and AKT activation.
Zhang X, Xu J, Zhuang G, Wang Y, Li X, Zhu X
Frontiers in immunology 2024;15:1477196
Frontiers in immunology 2024;15:1477196
Dl-3-n-butylphthalide attenuates cerebral ischemia/reperfusion injury in mice through AMPK-mediated mitochondrial fusion.
Zhu T, Dong S, Qin N, Liu R, Shi L, Wan Q
Frontiers in pharmacology 2024;15:1357953
Frontiers in pharmacology 2024;15:1357953
FUNDC1 alleviates doxorubicin-induced cardiotoxicity by restoring mitochondrial-endoplasmic reticulum contacts and blocked autophagic flux.
He W, Sun Z, Tong G, Zeng L, He W, Chen X, Zhen C, Chen P, Tan N, He P
Theranostics 2024;14(9):3719-3738
Theranostics 2024;14(9):3719-3738
Circular RNA SCMH1 suppresses KMO expression to inhibit mitophagy and promote functional recovery following stroke.
Wang Y, Bai Y, Cai Y, Zhang Y, Shen L, Xi W, Zhou Z, Xu L, Liu X, Han B, Yao H
Theranostics 2024;14(19):7292-7308
Theranostics 2024;14(19):7292-7308
β-arrestin1 protects intestinal tight junction through promoting mitofusin 2 transcription to drive parkin-dependent mitophagy in colitis.
Wu S, Liu H, Yi J, Xu M, Jiang J, Tao J, Wu B
Gastroenterology report 2024;12:goae084
Gastroenterology report 2024;12:goae084
PKD regulates mitophagy to prevent oxidative stress and mitochondrial dysfunction during mouse oocyte maturation.
Liu YP, He B, Wang WX, Pan WL, Jiao L, Yan JJ, Sun SC, Zhang Y
Mitochondrion 2024 Sep;78:101946
Mitochondrion 2024 Sep;78:101946
Targeting translocator protein protects against myocardial ischemia/reperfusion injury by alleviating mitochondrial dysfunction.
Wen C, Jiang Y, Chen W, Xu Y, Chen G, Zhou Q, Liu Q, Jiang H, Liu Y, Cao X, Yao Y, Zhang R, Qiu Z, Liu S
Experimental and therapeutic medicine 2024 Sep;28(3):349
Experimental and therapeutic medicine 2024 Sep;28(3):349
The potential benefits of PGC-1α in treating Alzheimer's disease are dependent on the integrity of the LLKYL L3 motif: Effect of regulating mitochondrial axonal transportation.
Shi HZ, Wang YJ, Wang YX, Xu LF, Pan W, Shi L, Wang J
Experimental gerontology 2024 Sep;194:112514
Experimental gerontology 2024 Sep;194:112514
PDK4-mediated Nrf2 inactivation contributes to oxidative stress and diabetic kidney injury.
Tian S, Yang X, Lin Y, Li X, Zhou S, Yu P, Zhao Y
Cellular signalling 2024 Sep;121:111282
Cellular signalling 2024 Sep;121:111282
Mesenchymal stem cells in tumor microenvironment: drivers of bladder cancer progression through mitochondrial dynamics and energy production.
Yang E, Jing S, Wang F, Wang H, Fu S, Yang L, Tian J, Golijanin DJ, El-Deiry WS, Cheng L, Wang Z
Cell death & disease 2024 Sep 20;15(9):688
Cell death & disease 2024 Sep 20;15(9):688
Helicobacter pylori CagA mediated mitophagy to attenuate the NLRP3 inflammasome activation and enhance the survival of infected cells.
Chen D, Wu L, Liu X, Wang Q, Gui S, Bao L, Wang Z, He X, Zhao Y, Zhou J, Xie Y
Scientific reports 2024 Sep 17;14(1):21648
Scientific reports 2024 Sep 17;14(1):21648
Dysregulation of mitochondrial dynamics and mitophagy are involved in high-fat diet-induced steroidogenesis inhibition.
Lv ZM, Liu C, Wang P, Chen YH
Journal of lipid research 2024 Oct;65(10):100639
Journal of lipid research 2024 Oct;65(10):100639
The tumor suppressor Parkin exerts anticancer effects through regulating mitochondrial GAPDH activity.
Sun X, Ye G, Li J, Yuan L, Bai G, Xu YJ, Zhang J
Oncogene 2024 Oct;43(44):3215-3226
Oncogene 2024 Oct;43(44):3215-3226
Neuronal HIPK2-HDAC3 axis regulates mitochondrial fragmentation to participate in stroke injury and post-stroke anxiety like behavior.
Yang M, Zhu H, Peng L, Yin T, Sun S, Du Y, Li J, Liu J, Wang S
Experimental neurology 2024 Oct;380:114906
Experimental neurology 2024 Oct;380:114906
Resveratrol protects against a high-fat diet-induced neuroinflammation by suppressing mitochondrial fission via targeting SIRT1/PGC-1α.
Su X, Li Q, Yang M, Zhang W, Liu X, Ba Y, Deng Q, Zhang Y, Han L, Huang H
Experimental neurology 2024 Oct;380:114899
Experimental neurology 2024 Oct;380:114899
SIRT1 regulates mitochondrial fission to alleviate high altitude hypoxia inducedcardiac dysfunction in rats via the PGC-1α-DRP1/FIS1/MFF pathway.
Xu H, Song X, Zhang X, Wang G, Cheng X, Zhang L, Wang Z, Li R, Ai C, Wang X, Pu L, Chen Z, Liu W
Apoptosis : an international journal on programmed cell death 2024 Oct;29(9-10):1663-1678
Apoptosis : an international journal on programmed cell death 2024 Oct;29(9-10):1663-1678
piR112710 attenuates diabetic cardiomyopathy through inhibiting Txnip/NLRP3-mediated pyroptosis in db/db mice.
Jiao A, Liu H, Wang H, Yu J, Gong L, Zhang H, Fu L
Cellular signalling 2024 Oct;122:111333
Cellular signalling 2024 Oct;122:111333
Qifu-yin activates the Keap1/Nrf2/ARE signaling and ameliorates synaptic injury and oxidative stress in APP/PS1 mice.
Wang S, Huang J, Chen Y, Liang Y, Chen L, Ye D, Yang H, Hui Z, Wang X, Zhang Z, Zhu X
Journal of ethnopharmacology 2024 Oct 28;333:118497
Journal of ethnopharmacology 2024 Oct 28;333:118497
Supplementation of Chlorogenic Acid Alleviates the Effects of H(2)O(2)-Induced Oxidative Stress on Laying Performance, Egg Quality, Antioxidant Capacity, Hepatic Inflammation, Mitochondrial Dysfunction, and Lipid Accumulation in Laying Hens.
Zhao H, Li Z, Sun Y, Yan M, Wang Y, Li Y, Zhang Y, Zhu M
Antioxidants (Basel, Switzerland) 2024 Oct 27;13(11)
Antioxidants (Basel, Switzerland) 2024 Oct 27;13(11)
SETDB1 targeting SESN2 regulates mitochondrial damage and oxidative stress in renal ischemia-reperfusion injury.
Xia K, Hui Y, Zhang L, Qiu Q, Zhong J, Chen H, Liu X, Wang L, Chen Z
BMC biology 2024 Oct 23;22(1):246
BMC biology 2024 Oct 23;22(1):246
Pseudorabies virus infection triggers mitophagy to dampen the interferon response and promote viral replication.
Zhao Y, Ding C, Zhu Z, Wang W, Wen W, Favoreel HW, Li X
Journal of virology 2024 Oct 22;98(10):e0104824
Journal of virology 2024 Oct 22;98(10):e0104824
Apoptosis, Mitochondrial Autophagy, Fission, and Fusion Maintain Mitochondrial Homeostasis in Mouse Liver Under Tail Suspension Conditions.
Li LF, Yu J, Li R, Li SS, Huang JY, Wang MD, Jiang LN, Xu JH, Wang Z
International journal of molecular sciences 2024 Oct 18;25(20)
International journal of molecular sciences 2024 Oct 18;25(20)
Dapagliflozin alleviates right heart failure by promoting collagen degradation by reducing ROS levels.
Liu DD, Liu XL, Zheng TF, Li X, Zhao YC, Pan JC, Yuan C, Wang QQ, Zhang M
European journal of pharmacology 2024 Oct 15;981:176875
European journal of pharmacology 2024 Oct 15;981:176875
Copper induced cytosolic escape of mitochondrial DNA and activation of cGAS-STING-NLRP3 pathway-dependent pyroptosis in C8-D1A cells.
Shi W, Zhou Q, Lu L, Zhang Y, Zhang H, Pu Y, Yin L
Ecotoxicology and environmental safety 2024 Oct 15;285:117085
Ecotoxicology and environmental safety 2024 Oct 15;285:117085
Characterization of fission and fusion mitochondrial dynamics in HD fibroblasts according to patient's severity status.
Gharaba S, Sprecher U, Baransi A, Muchtar N, Weil M
Neurobiology of disease 2024 Oct 15;201:106667
Neurobiology of disease 2024 Oct 15;201:106667
Yiqihuoxue decoction (GSC) inhibits mitochondrial fission through the AMPK pathway to ameliorate EPCs senescence and optimize vascular aging transplantation regimens.
Liu Y, Niu Z, Wang X, Xiu C, Hu Y, Wang J, Lei Y, Yang J
Chinese medicine 2024 Oct 14;19(1):143
Chinese medicine 2024 Oct 14;19(1):143
SGLT2 inhibitor canagliflozin reduces visceral adipose tissue in db/db mice by modulating AMPK/KLF4 signaling and regulating mitochondrial dynamics to induce browning.
Qu J, Tian L, Zhang M, Sun B, Chen L
Molecular and cellular endocrinology 2024 Oct 1;592:112320
Molecular and cellular endocrinology 2024 Oct 1;592:112320
Readdressing the Localization of Apolipoprotein E (APOE) in Mitochondria-Associated Endoplasmic Reticulum (ER) Membranes (MAMs): An Investigation of the Hepatic Protein-Protein Interactions of APOE with the Mitochondrial Proteins Lon Protease (LONP1), Mitochondrial Import Receptor Subunit TOM40 (TOMM40) and Voltage-Dependent Anion-Selective Channel 1 (VDAC1).
Rueter J, Rimbach G, Bilke S, Tholey A, Huebbe P
International journal of molecular sciences 2024 Oct 1;25(19)
International journal of molecular sciences 2024 Oct 1;25(19)
Contribution of impaired autophagy, mitochondrial dysfunction and abnormal lipolysis to epididymal aging in mice.
Liu C, Wu C, Zhang S, Lv Z
Experimental gerontology 2024 Oct 1;195:112528
Experimental gerontology 2024 Oct 1;195:112528
Isoliquiritigenin alleviates cerebral ischemia-reperfusion injury by reducing oxidative stress and ameliorating mitochondrial dysfunction via activating the Nrf2 pathway.
Lan X, Wang Q, Liu Y, You Q, Wei W, Zhu C, Hai D, Cai Z, Yu J, Zhang J, Liu N
Redox biology 2024 Nov;77:103406
Redox biology 2024 Nov;77:103406
Diallyl disulfide alleviates hepatic steatosis by the conservative mechanism from fish to tetrapod: Augment Mfn2/Atgl-Mediated lipid droplet-mitochondria coupling.
Wang LJ, Lai XH, Luo Z, Feng GL, Song YF
Redox biology 2024 Nov;77:103395
Redox biology 2024 Nov;77:103395
SIRT1, a target of miR-708-3p, alleviates fluoride-induced neuronal damage via remodeling mitochondrial network dynamics.
Zhao Q, Zhou GY, Niu Q, Chen JW, Li P, Tian ZY, Li DJ, Xia T, Zhang S, Wang AG
Journal of advanced research 2024 Nov;65:197-210
Journal of advanced research 2024 Nov;65:197-210
Cellular ATP demand creates metabolically distinct subpopulations of mitochondria.
Ryu KW, Fung TS, Baker DC, Saoi M, Park J, Febres-Aldana CA, Aly RG, Cui R, Sharma A, Fu Y, Jones OL, Cai X, Pasolli HA, Cross JR, Rudin CM, Thompson CB
Nature 2024 Nov;635(8039):746-754
Nature 2024 Nov;635(8039):746-754
E3 ubiquitin ligase TRIM31 alleviates dopaminergic neurodegeneration by promoting proteasomal degradation of VDAC1 in Parkinson's Disease model.
Zhao Z, Song X, Wang Y, Yu L, Huang G, Li Y, Zong R, Liu T, Ji Q, Zheng Y, Liu B, Zhu Q, Chen L, Gao C, Liu H
Cell death and differentiation 2024 Nov;31(11):1410-1421
Cell death and differentiation 2024 Nov;31(11):1410-1421
Hydrogen Protects Mitochondrial Function by Increasing the Expression of PGC-1α and Ameliorating Myocardial Ischaemia-Reperfusion Injury.
Zuo Y, Wang J, Gong Z, Wang Y, Wang Q, Yang X, Liu F, Liu T
Journal of cellular and molecular medicine 2024 Nov;28(22):e70236
Journal of cellular and molecular medicine 2024 Nov;28(22):e70236
Mitochondrial elongation confers protection against doxorubicin-induced cardiotoxicity.
He W, He W, Chen X, Zeng L, Zeng L, Liu Y, He P, Sun Z
Biochemical pharmacology 2024 Nov;229:116495
Biochemical pharmacology 2024 Nov;229:116495
Endothelial Birc3 promotes renal fibrosis through modulating Drp1-mediated mitochondrial fission via MAPK/PI3K/Akt pathway.
Chen S, He Q, Yang H, Huang H
Biochemical pharmacology 2024 Nov;229:116477
Biochemical pharmacology 2024 Nov;229:116477
Ligustilide alleviates oxidative stress during renal ischemia-reperfusion injury through maintaining Sirt3-dependent mitochondrial homeostasis.
Xia K, Jin Z, Qiu Q, Zhou Y, Lu Y, Qiu T, Zhou J, Chen Z
Phytomedicine : international journal of phytotherapy and phytopharmacology 2024 Nov;134:155975
Phytomedicine : international journal of phytotherapy and phytopharmacology 2024 Nov;134:155975
Endo-Lysosomal Network Disorder Reprograms Energy Metabolism in SorL1-Null Rat Hippocampus.
Wang Y, Yang Y, Cai Y, Aobulikasimu A, Wang Y, Hu C, Miao Z, Shao Y, Zhao M, Hu Y, Xu C, Chen X, Li Z, Chen J, Wang L, Chen S
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2024 Nov;11(41):e2407709
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2024 Nov;11(41):e2407709
Diacylglycerol O-acyltransferase isoforms play a role in peridroplet mitochondrial fatty acid metabolism in bovine liver.
Wang S, Zhang B, Mauck J, Loor JJ, Fan W, Tian Y, Yang T, Chang Y, Xie M, Aernouts B, Yang W, Xu C
Journal of dairy science 2024 Nov;107(11):9897-9914
Journal of dairy science 2024 Nov;107(11):9897-9914
Psmb8 inhibits mitochondrial fission and alleviates myocardial ischaemia/reperfusion injury by targeting Drp1 degradation.
Su HX, Xu LL, Li PB, Bi HL, Jiang WX, Li HH
Cell death & disease 2024 Nov 8;15(11):803
Cell death & disease 2024 Nov 8;15(11):803
Therapeutic utility of Perfluorocarbon Oxygent in limiting the severity of subarachnoid hemorrhage in mice.
Ahmed ME, Akhter N, Fatima S, Ahmad S, Giri S, Hoda MN, Ahmad AS
Scientific reports 2024 Nov 4;14(1):26638
Scientific reports 2024 Nov 4;14(1):26638
ACSL1 improves pulmonary fibrosis by reducing mitochondrial damage and activating PINK1/Parkin mediated mitophagy.
Lin Q, Lin Y, Liao X, Chen Z, Deng M, Zhong Z
Scientific reports 2024 Nov 3;14(1):26504
Scientific reports 2024 Nov 3;14(1):26504
Procyanidin C1 ameliorates acidic pH stress induced nucleus pulposus degeneration through SIRT3/FOXO3-mediated mitochondrial dynamics.
Hua W, Xie L, Dong C, Yang G, Chi S, Xu Z, Yang C, Wang H, Wu X
Journal of translational medicine 2024 Nov 27;22(1):1071
Journal of translational medicine 2024 Nov 27;22(1):1071
Targeting DUSP26 to drive cardiac mitochondrial dynamics via FAK-ERK signaling in diabetic cardiomyopathy.
Liu C, Xu X, Sun G, Song C, Jiang S, Sun P, Tian J
Free radical biology & medicine 2024 Nov 20;225:856-870
Free radical biology & medicine 2024 Nov 20;225:856-870
Schwann cell-secreted frizzled-related protein 1 dictates neuroinflammation and peripheral nerve degeneration after neurotrauma.
Yao X, Kong L, Qiao Y, Brand D, Li J, Yan Z, Zheng SG, Qian Y, Fan C
Cell reports. Medicine 2024 Nov 19;5(11):101791
Cell reports. Medicine 2024 Nov 19;5(11):101791
Acrolein exposure affects ovarian function by interfering with glycolysis and mitochondrial energy metabolism in mouse.
Chen YZ, Wang WK, Yang YF, Cheng SY, Li LF, Shen H, Qi ZM, Liu Y
Environmental pollution (Barking, Essex : 1987) 2024 Nov 15;361:124776
Environmental pollution (Barking, Essex : 1987) 2024 Nov 15;361:124776
TRPA1 protects against contrast-induced renal tubular injury by preserving mitochondrial dynamics via the AMPK/DRP1 pathway.
Wang X, Luo T, Yang Y, Yang L, Liu M, Zou Q, Wang D, Yang C, Xue Q, Liu S, Wan J, He G, Zeng A, Hou J, Ma S, Wang P
Free radical biology & medicine 2024 Nov 1;224:521-539
Free radical biology & medicine 2024 Nov 1;224:521-539
Hydrogen sulfide upregulates SIRT1 to inhibit ox-HDL-induced endothelial cell damage and mitochondrial dysfunction.
Zhao Y, Wang Y, Zheng H, Xu Q, Zhou K, Liu H, Xia Y, Wei DH, Jiang M, Tang ZH, Liu LS, Zheng H, Jiang Z
Nitric oxide : biology and chemistry 2024 Nov 1;152:78-89
Nitric oxide : biology and chemistry 2024 Nov 1;152:78-89
Deafness-associated tRNA(Phe) mutation impaired mitochondrial and cellular integrity.
Chen X, Meng F, Chen C, Li S, Chou Z, Xu B, Mo JQ, Guo Y, Guan MX
The Journal of biological chemistry 2024 May;300(5):107235
The Journal of biological chemistry 2024 May;300(5):107235
Human neural stem cells promote mitochondrial genesis to alleviate neuronal damage in MPTP-induced cynomolgus monkey models.
He Y, Li R, Yu Y, Huang C, Xu Z, Wang T, Chen M, Huang H, Qi Z
Neurochemistry international 2024 May;175:105700
Neurochemistry international 2024 May;175:105700
Exercise ameliorates muscular excessive mitochondrial fission, insulin resistance and inflammation in diabetic rats via irisin/AMPK activation.
Lin J, Zhang X, Sun Y, Xu H, Li N, Wang Y, Tian X, Zhao C, Wang B, Zhu B, Zhao R
Scientific reports 2024 May 9;14(1):10658
Scientific reports 2024 May 9;14(1):10658
BAG3 localizes to mitochondria in cardiac fibroblasts and regulates mitophagy.
Martin TG, Sherer LA, Kirk JA
American journal of physiology. Heart and circulatory physiology 2024 May 1;326(5):H1124-H1130
American journal of physiology. Heart and circulatory physiology 2024 May 1;326(5):H1124-H1130
Alpha-ketoglutaric acid attenuates oxidative stress and modulates mitochondrial dynamics and autophagy of spleen in a piglet model of lipopolysaccharide-induced sepsis.
Liu G, Lu J, Sun W, Jia G, Zhao H, Chen X, Wang J
Free radical biology & medicine 2024 Mar;214:80-86
Free radical biology & medicine 2024 Mar;214:80-86
IGF2BP3-stabilized CAMK1 regulates the mitochondrial dynamics of renal tubule to alleviate diabetic nephropathy.
Yuan D, Li H, Dai W, Zhou X, Zhou W, He L
Biochimica et biophysica acta. Molecular basis of disease 2024 Mar;1870(3):167022
Biochimica et biophysica acta. Molecular basis of disease 2024 Mar;1870(3):167022
Non-cytopathic bovine viral diarrhea virus (BVDV) inhibits innate immune responses via induction of mitophagy.
Li Z, Zhang Y, Zhao B, Xue Q, Wang C, Wan S, Wang J, Chen X, Qi X
Veterinary research 2024 Mar 5;55(1):27
Veterinary research 2024 Mar 5;55(1):27
Proteomic analysis of mitochondria associated membranes in renal ischemic reperfusion injury.
Li Y, Wang HB, Cao JL, Zhang WJ, Wang HL, Xu CH, Li KP, Liu Y, Wang JR, Ha HL, Fu SJ, Yang L
Journal of translational medicine 2024 Mar 10;22(1):261
Journal of translational medicine 2024 Mar 10;22(1):261
Differential impact of sex on regulation of skeletal muscle mitochondrial function and protein homeostasis by hypoxia-inducible factor-1α in normoxia.
Welch N, Mishra S, Bellar A, Kannan P, Gopan A, Goudarzi M, King J, Luknis M, Musich R, Agrawal V, Bena J, Koch CJ, Li L, Willard B, Shah YM, Dasarathy S
The Journal of physiology 2024 Jun;602(12):2763-2806
The Journal of physiology 2024 Jun;602(12):2763-2806
CGI1746 targets σ(1)R to modulate ferroptosis through mitochondria-associated membranes.
Zhang Z, Zhou H, Gu W, Wei Y, Mou S, Wang Y, Zhang J, Zhong Q
Nature chemical biology 2024 Jun;20(6):699-709
Nature chemical biology 2024 Jun;20(6):699-709
ACSF2 and lysine lactylation contribute to renal tubule injury in diabetes.
Chen J, Feng Q, Qiao Y, Pan S, Liang L, Liu Y, Zhang X, Liu D, Liu Z, Liu Z
Diabetologia 2024 Jul;67(7):1429-1443
Diabetologia 2024 Jul;67(7):1429-1443
Decreasing mitochondrial fission ameliorates HIF-1α-dependent pathological retinal angiogenesis.
Huang SQ, Cao KX, Wang CL, Chen PL, Chen YX, Zhang YT, Yu SH, Bai ZX, Guo S, Liao MX, Li QW, Zhang GQ, He J, Xu YM
Acta pharmacologica Sinica 2024 Jul;45(7):1438-1450
Acta pharmacologica Sinica 2024 Jul;45(7):1438-1450
Mitofusin 2 plays a critical role in maintaining the functional integrity of the neuromuscular-skeletal axis.
Zhu M, Zeiss C, Hamrick MW, Weinstein RS, Sun BH, Brotto M, Liu X, Siu E, Huttner A, Tommasini S, Simpson C, Insogna K
Bone 2024 Jul;184:117086
Bone 2024 Jul;184:117086
Dietary α-Ketoglutarate Alleviates Escherichia coli LPS-Induced Intestinal Barrier Injury by Modulating the Endoplasmic Reticulum-Mitochondrial System Pathway in Piglets.
Lu J, Liu G, Sun W, Jia G, Zhao H, Chen X, Wang J
The Journal of nutrition 2024 Jul;154(7):2087-2096
The Journal of nutrition 2024 Jul;154(7):2087-2096
Acid Neutralization by Composite Lysine Nanoparticles for Spinal Cord Injury Recovery through Mitigating Mitochondrial Dysfunction.
Wang Q, Ge L, Guo J, Zhang H, Chen T, Lian F, Li L, Xu Y, Xu J, Chen N, Zhang Y, Ruan Z, Xiao J, Zhang H, Yang L
ACS biomaterials science & engineering 2024 Jul 8;10(7):4480-4495
ACS biomaterials science & engineering 2024 Jul 8;10(7):4480-4495
Targeting the smooth muscle cell KEAP1-Nrf2-STING axis with pterostilbene attenuates abdominal aortic aneurysm.
Zou J, Zheng Z, Ye W, Jin M, Yang P, Little PJ, Wang J, Liu Z
Phytomedicine : international journal of phytotherapy and phytopharmacology 2024 Jul 25;130:155696
Phytomedicine : international journal of phytotherapy and phytopharmacology 2024 Jul 25;130:155696
Zearalenone modulates the function of goat endometrial cells via the mitochondrial quality control system.
Zhang G, Zeng C, Sun X, Zhang Q, Wang Y, Xia R, Mai Q, Xue G, Huang H, Wang F
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2024 Jul 15;38(13):e23701
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2024 Jul 15;38(13):e23701
Mitofusin2 Ameliorated Endoplasmic Reticulum Stress and Mitochondrial Reactive Oxygen Species Through Maintaining Mitochondria-Associated Endoplasmic Reticulum Membrane Integrity in Cisplatin-Induced Acute Kidney Injury.
Liu YT, Zhang H, Duan SB, Wang JW, Chen H, Zhan M, Zhang W, Li AM, Liu Y, Yang Y, Yang S
Antioxidants & redox signaling 2024 Jan;40(1-3):16-39
Antioxidants & redox signaling 2024 Jan;40(1-3):16-39
Sentrin-specific protease 1 maintains mitochondrial homeostasis through targeting the deSUMOylation of sirtuin-3 to alleviate oxidative damage induced by hepatic ischemia/reperfusion.
Xia K, Guo J, Yu B, Wang T, Qiu Q, Chen Q, Qiu T, Zhou J, Zheng S
Free radical biology & medicine 2024 Jan;210:378-389
Free radical biology & medicine 2024 Jan;210:378-389
Cytoplasmic Escape of Mitochondrial DNA Mediated by Mfn2 Downregulation Promotes Microglial Activation via cGas-Sting Axis in Spinal Cord Injury.
Wei FL, Wang TF, Wang CL, Zhang ZP, Zhao JW, Heng W, Tang Z, Du MR, Yan XD, Li XX, Guo Z, Qian JX, Zhou CP
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2024 Jan;11(4):e2305442
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2024 Jan;11(4):e2305442
Drp1 regulated PINK1-dependent mitophagy protected duck follicular granulosa cells from acute heat stress injury.
Yang C, Luo P, Yang YT, Fu XL, Li BX, Shen X, Xu DN, Huang YM, Tian YB, Liu WJ
Poultry science 2024 Jan;103(1):103247
Poultry science 2024 Jan;103(1):103247
High-fat diet-induced L-saccharopine accumulation inhibits estradiol synthesis and damages oocyte quality by disturbing mitochondrial homeostasis.
Wen J, Feng Y, Xue L, Yuan S, Chen Q, Luo A, Wang S, Zhang J
Gut microbes 2024 Jan-Dec;16(1):2412381
Gut microbes 2024 Jan-Dec;16(1):2412381
Uncovering impaired mitochondrial and lysosomal function in adipose-derived stem cells from obese individuals with altered biological activity.
Wang B, Zhang G, Hu Y, Mohsin A, Chen Z, Hao W, Li Z, Gao WQ, Guo M, Xu H
Stem cell research & therapy 2024 Jan 8;15(1):12
Stem cell research & therapy 2024 Jan 8;15(1):12
Dietary xylo-oligosaccharides alleviates LPS-induced intestinal injury via endoplasmic reticulum-mitochondrial system pathway in piglets.
Liu G, Sun W, Zhang R, Shen F, Jia G, Zhao H, Chen X, Wang J
Journal of animal science 2024 Jan 3;102
Journal of animal science 2024 Jan 3;102
MCT1-governed pyruvate metabolism is essential for antibody class-switch recombination through H3K27 acetylation.
Chi W, Kang N, Sheng L, Liu S, Tao L, Cao X, Liu Y, Zhu C, Zhang Y, Wu B, Chen R, Cheng L, Wang J, Sun X, Liu X, Deng H, Yang J, Li Z, Liu W, Chen L
Nature communications 2024 Jan 2;15(1):163
Nature communications 2024 Jan 2;15(1):163
Prenatal hormone stress triggers embryonic cardiac hypertrophy outcome by ubiquitin-dependent degradation of mitochondrial mitofusin 2.
Yan CY, Ye Y, Mu HL, Wu T, Huang WS, Wu YP, Sun WY, Liang L, Duan WJ, Ouyang SH, Huang RT, Wang R, Sun XX, Kurihara H, Li YF, He RR
iScience 2024 Jan 19;27(1):108690
iScience 2024 Jan 19;27(1):108690
Aluminum-maltol induced oxidative stress and reduced AMPK activity via BCK-related energy supply failure in C6 cell.
Wang Y, Yu Q, Liu S, Liu C, Ju Y, Song Q, Cheng D
Ecotoxicology and environmental safety 2024 Jan 15;270:115831
Ecotoxicology and environmental safety 2024 Jan 15;270:115831
Fluorochloridone induces mitochondrial dysfunction and apoptosis in primary goat Sertoli cells.
Li Y, Li L, Xiong W, Duan X, Xi H
Theriogenology 2024 Jan 15;214:192-200
Theriogenology 2024 Jan 15;214:192-200
MicroRNA-129-1-3p protects chicken granulosa cells from cadmium-induced apoptosis by down-regulating the MCU-mediated Ca(2+) signaling pathway.
Zhu M, Yan M, Musa M, Li Y, Zhang Y, Zou X
Ecotoxicology and environmental safety 2024 Jan 1;269:115906
Ecotoxicology and environmental safety 2024 Jan 1;269:115906
Intermittent Theta Burst Stimulation Attenuates Cognitive Deficits and Alzheimer's Disease-Type Pathologies via ISCA1-Mediated Mitochondrial Modulation in APP/PS1 Mice.
Zhu Y, Huang H, Chen Z, Tao Y, Liao LY, Gao SH, Wang YJ, Gao CY
Neuroscience bulletin 2024 Feb;40(2):182-200
Neuroscience bulletin 2024 Feb;40(2):182-200
AGK2 pre-treatment protects against thioacetamide-induced acute liver failure via regulating the MFN2-PERK axis and ferroptosis signaling pathway.
Zhang QQ, Chen Q, Cao P, Shi CX, Zhang LY, Wang LW, Gong ZJ
Hepatobiliary & pancreatic diseases international : HBPD INT 2024 Feb;23(1):43-51
Hepatobiliary & pancreatic diseases international : HBPD INT 2024 Feb;23(1):43-51
NSD2 modulates Drp1-mediated mitochondrial fission in chronic renal allograft interstitial fibrosis by methylating STAT1.
Zhang J, Xie W, Ni B, Li Z, Feng D, Zhang Y, Han Q, Zhou H, Gu M, Tan R
Pharmacological research 2024 Feb;200:107051
Pharmacological research 2024 Feb;200:107051
Blockade of angiotensin II modulates insulin-like growth factor 1-mediated skeletal muscle homeostasis in experimental steatohepatitis.
Tanaka M, Kaji K, Nishimura N, Asada S, Koizumi A, Matsuda T, Yorioka N, Tsuji Y, Fujinaga Y, Sato S, Namisaki T, Akahane T, Yoshiji H
Biochimica et biophysica acta. Molecular cell research 2024 Feb;1871(2):119649
Biochimica et biophysica acta. Molecular cell research 2024 Feb;1871(2):119649
Photobiomodulation therapy alleviates repeated closed head injury-induced anxiety-like behaviors.
Chen Z, Li M, Wu C, Su Y, Feng S, Deng Q, Zou P, Liu TC, Duan R, Yang L
Journal of biophotonics 2024 Feb;17(2):e202300343
Journal of biophotonics 2024 Feb;17(2):e202300343
Effects of metformin on glucose metabolism and mitochondrial function in patients with obstructive sleep apnea: A pilot randomized trial.
Zunica ERM, Heintz EC, Dantas WS, Hebert RC, Tanksley M, Beyl RA, Mader EC Jr, Kirwan JP, Axelrod CL, Singh P
Physiological reports 2024 Feb;12(3):e15948
Physiological reports 2024 Feb;12(3):e15948
Coenzyme Q10 Protects Against Hyperlipidemia-Induced Osteoporosis by Improving Mitochondrial Function via Modulating miR-130b-3p/PGC-1α Pathway.
Meng M, Wang J, Wang C, Zhao J, Wang H, Zhang Y, Sun H, Liu M
Calcified tissue international 2024 Feb;114(2):182-199
Calcified tissue international 2024 Feb;114(2):182-199
The E3 ubiquitin ligase MARCH2 protects against myocardial ischemia-reperfusion injury through inhibiting pyroptosis via negative regulation of PGAM5/MAVS/NLRP3 axis.
Liu S, Bi Y, Han T, Li YE, Wang Q, Wu NN, Xu C, Ge J, Hu R, Zhang Y
Cell discovery 2024 Feb 27;10(1):24
Cell discovery 2024 Feb 27;10(1):24
Mitochondria-mediated ferroptosis contributes to the inflammatory responses of bovine viral diarrhea virus (BVDV) in vitro.
Li Z, Zhao B, Zhang Y, Fan W, Xue Q, Chen X, Wang J, Qi X
Journal of virology 2024 Feb 20;98(2):e0188023
Journal of virology 2024 Feb 20;98(2):e0188023
Deficient tRNA posttranscription modification dysregulated the mitochondrial quality controls and apoptosis.
He Y, Zhu G, Li X, Zhou M, Guan MX
iScience 2024 Feb 16;27(2):108883
iScience 2024 Feb 16;27(2):108883
Serine synthesis sustains macrophage IL-1β production via NAD(+)-dependent protein acetylation.
Wang C, Chen Q, Chen S, Fan L, Gan Z, Zhao M, Shi L, Bin P, Yang G, Zhou X, Ren W
Molecular cell 2024 Feb 15;84(4):744-759.e6
Molecular cell 2024 Feb 15;84(4):744-759.e6
Antrodia cinnamomea triterpenoids attenuate cardiac hypertrophy via the SNW1/RXR/ALDH2 axis.
Ma Y, Wang Y, Anwaier G, Tuerdi N, Wu Y, Huang Y, Qin B, Ma H, Zhang Q, Wu D, Zeng K, Qi R
Redox biology 2024 Dec;78:103437
Redox biology 2024 Dec;78:103437
Halofuginone ameliorates the susceptibility to atrial fibrillation by activating the PI3K/Akt signaling pathway.
Xu F, Zhao X, Zhang J, Shen C
Journal of molecular histology 2024 Dec;55(6):1295-1306
Journal of molecular histology 2024 Dec;55(6):1295-1306
Particulate matter induced cognitive impairments via endoplasmic reticulum stress-mediated damage to mitochondria-associated endoplasmic reticulum membranes in immature rats.
Wang L, Gui J, Tian B, Ding R, Wang W, Jiang C, Zhang S, Zhang X, Liu J, Jiang L
Toxicology 2024 Dec;509:153979
Toxicology 2024 Dec;509:153979
Sirt3-Mediated Opa1 Deacetylation Protects Against Sepsis-Induced Acute Lung Injury by Inhibiting Alveolar Macrophage Pro-Inflammatory Polarization.
Sun M, Li Y, Xu G, Zhu J, Lu R, An S, Zeng Z, Deng Z, Cheng R, Zhang Q, Yao Y, Wu J, Zhang Y, Hu H, Chen Z, Huang Q, Wu J
Antioxidants & redox signaling 2024 Dec;41(16-18):1014-1030
Antioxidants & redox signaling 2024 Dec;41(16-18):1014-1030
Regulatory roles of histamine receptor in astrocytic glutamate clearance under conditions of increased glucose variability.
Zhou Y, Xie W, Kong C, Luo W, Wei H, Zheng J
Biochemical pharmacology 2024 Dec;230(Pt 3):116611
Biochemical pharmacology 2024 Dec;230(Pt 3):116611
New TIPARP inhibitor rescues mitochondrial function and brain injury in ischemic stroke.
Cai Y, Gu H, Li L, Liu X, Bai Y, Shen L, Han B, Xu Y, Yao H
Pharmacological research 2024 Dec;210:107508
Pharmacological research 2024 Dec;210:107508
Oleanonic acid ameliorates mutant Aβ precursor protein-induced oxidative stress, autophagy deficits, ferroptosis, mitochondrial damage, and ER stress in vitro.
Tao L, Liu Z, Li X, Wang H, Wang Y, Zhou D, Zhang H
Biochimica et biophysica acta. Molecular basis of disease 2024 Dec;1870(8):167459
Biochimica et biophysica acta. Molecular basis of disease 2024 Dec;1870(8):167459
Activated DRP1 promotes mitochondrial fission and induces glycolysis in ATII cells under hyperoxia.
Sun T, Yu H, Zhang D, Li D, Fu J
Respiratory research 2024 Dec 26;25(1):443
Respiratory research 2024 Dec 26;25(1):443
SUCNR 1 promotes atherosclerosis by inducing endoplasmic reticulum stress mediated ER-mito crosstalk.
Yuan C, Yu B, Li L, Chen J, Qin W, Zhou Z, Su M, Wang D, Zhang Y, Wu Q, He C, Wei D
International immunopharmacology 2024 Dec 25;143(Pt 3):113510
International immunopharmacology 2024 Dec 25;143(Pt 3):113510
High concentration hydrogen attenuates sepsis-induced acute kidney injury by promoting mitochondrial biogenesis and fusion.
Pei S, Zheng L, Tian Z, Meng S, Wang Z, Fan Y, Liu J, Cui Y, Xie K
International immunopharmacology 2024 Dec 25;143(Pt 2):113410
International immunopharmacology 2024 Dec 25;143(Pt 2):113410
Aflatoxin B1 Promotes Pyroptosis in IPEC-J2 Cells by Disrupting Mitochondrial Dynamics through the AMPK/NLRP3 Pathway.
Ding J, Cheng X, Zeng C, Zhao Q, Xing C, Zhang C, Cao H, Guo X, Hu G, Zhuang Y
Journal of agricultural and food chemistry 2024 Dec 18;72(50):28093-28108
Journal of agricultural and food chemistry 2024 Dec 18;72(50):28093-28108
Myricetin Alleviates Silica-Mediated Lung Fibrosis via PPARγ-PGC-1α Loop and Suppressing Mitochondrial Senescence in Epithelial Cells.
Xie W, Deng L, Zhang X, Huang X, Ding J, Liu W, Tang SY
Journal of agricultural and food chemistry 2024 Dec 18;72(50):27737-27749
Journal of agricultural and food chemistry 2024 Dec 18;72(50):27737-27749
Disturbance of mitochondrial dynamics led to spermatogenesis disorder in mice exposed to polystyrene micro- and nanoplastics.
Zhao M, Xie J, Zhang J, Zhao B, Zhang Y, Xue J, Zhang R, Zhang R, Wang H, Li Y, Ge W, Zhou X
Environmental pollution (Barking, Essex : 1987) 2024 Dec 1;362:124935
Environmental pollution (Barking, Essex : 1987) 2024 Dec 1;362:124935
Impaired mitochondrial quality control in fibromyalgia: Mechanisms involved in skeletal muscle alteration.
Inferrera F, Marino Y, D'Amico R, Impellizzeri D, Cordaro M, Siracusa R, Gugliandolo E, Fusco R, Cuzzocrea S, Di Paola R
Archives of biochemistry and biophysics 2024 Aug;758:110083
Archives of biochemistry and biophysics 2024 Aug;758:110083
Activating MC4R Promotes Functional Recovery by Repressing Oxidative Stress-Mediated AIM2 Activation Post-spinal Cord Injury.
Wang Y, Fang N, Wang Y, Geng Y, Li Y
Molecular neurobiology 2024 Aug;61(8):6101-6118
Molecular neurobiology 2024 Aug;61(8):6101-6118
Repeated Ketamine Anesthesia during the Neonatal Period Impairs Hippocampal Neurogenesis and Long-Term Neurocognitive Function by Inhibiting Mfn2-Mediated Mitochondrial Fusion in Neural Stem Cells.
Huang H, Wang N, Lin JT, Qiu YK, Wu WF, Liu Q, Chen C, Wang HB, Liu YP, Dong W, Wan J, Zheng H, Zhou CH, Wu YQ
Molecular neurobiology 2024 Aug;61(8):5459-5480
Molecular neurobiology 2024 Aug;61(8):5459-5480
Presenilin2 D439A Mutation Induces Dysfunction of Mitochondrial Fusion/Fission Dynamics and Abnormal Regulation of GTPase Activity.
Gao C, Shang J, Sun Z, Xia M, Gao D, Sun R, Li W, Wang F, Zhang J
Molecular neurobiology 2024 Aug;61(8):5047-5070
Molecular neurobiology 2024 Aug;61(8):5047-5070
Icariin Ameliorates D-galactose-induced Cell Injury in Neuron-like PC12 Cells by Inhibiting MPTP Opening.
Hu SS, Wang TY, Ni L, Hu FX, Yue BW, Zheng Y, Wang TL, Kumar A, Wang YY, Wang JE, Zhou ZY
Current medical science 2024 Aug;44(4):748-758
Current medical science 2024 Aug;44(4):748-758
MicroRNA-15b promotes cardiac ischemia injury by the inhibition of Mitofusin 2/PERK pathway.
Zhang W, Zhang M, Ma J, Yao Y, Jiang Y, Huo Q, Jin S, Ji D, Zhao Y, Liu X, Sun H, Xu C, Zhang R
Biochemical pharmacology 2024 Aug;226:116372
Biochemical pharmacology 2024 Aug;226:116372
Aldehyde Dehydrogenase 2 Deficiency Aggravates Lung Fibrosis through Mitochondrial Dysfunction and Aging in Fibroblasts.
Wei Y, Gao S, Li C, Huang X, Xie B, Geng J, Dai H, Wang C
The American journal of pathology 2024 Aug;194(8):1458-1477
The American journal of pathology 2024 Aug;194(8):1458-1477
The effects of the atrial natriuretic peptide deficiency on renal cortical mitochondrial bioenergetics in the Dahl SS rat.
Cherezova A, Sudarikova A, Vasileva V, Iurchenko R, Nikiforova A, Spires DR, Zamaro AS, Jones AC, Schibalski RS, Dong Z, Palygin O, Stadler K, Ilatovskaya DV
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2024 Aug 31;38(16):e23891
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2024 Aug 31;38(16):e23891
Tetramerization of PKM2 Alleviates Traumatic Brain Injury by Ameliorating Mitochondrial Damage in Microglia.
Zhu H, Zhang H, Zhao XJ, Zhang L, Liu X, Zhang ZY, Ren YZ, Feng Y
Journal of neuroimmune pharmacology : the official journal of the Society on NeuroImmune Pharmacology 2024 Aug 28;19(1):48
Journal of neuroimmune pharmacology : the official journal of the Society on NeuroImmune Pharmacology 2024 Aug 28;19(1):48
Mannan-binding lectin inhibits oxidative stress-induced senescence via the NAD+/Sirt1 pathway.
Lei Y, Meng J, Shi H, Shi C, Li C, Yang Z, Zhang W, Zuo D, Wang F, Wang M
International immunopharmacology 2024 Aug 20;137:112468
International immunopharmacology 2024 Aug 20;137:112468
The mechanism of extracellular CypB promotes glioblastoma adaptation to glutamine deprivation microenvironment.
Yin H, Liu Y, Dong Q, Wang H, Yan Y, Wang X, Wan X, Yuan G, Pan Y
Cancer letters 2024 Aug 10;597:216862
Cancer letters 2024 Aug 10;597:216862
VDR regulates mitochondrial function as a protective mechanism against renal tubular cell injury in diabetic rats.
Chen H, Zhang H, Li AM, Liu YT, Liu Y, Zhang W, Yang C, Song N, Zhan M, Yang S
Redox biology 2024 Apr;70:103062
Redox biology 2024 Apr;70:103062
Disturbance of mitochondrial dynamics in myocardium of broilers with pulmonary hypertension syndrome.
Zhang W, Li M, Ye X, Jiang M, Wu X, Tang Z, Hu L, Zhang H, Li Y, Pan J
British poultry science 2024 Apr;65(2):154-164
British poultry science 2024 Apr;65(2):154-164
DsbA-L ameliorates renal aging and renal fibrosis by maintaining mitochondrial homeostasis.
Yang M, Liu Y, Luo SL, Liu CB, Jiang N, Li CR, Zhao H, Han YC, Chen W, Li L, Sun L
Acta pharmacologica Sinica 2024 Apr;45(4):777-789
Acta pharmacologica Sinica 2024 Apr;45(4):777-789
Astragaloside IV combined with ligustrazine ameliorates abnormal mitochondrial dynamics via Drp1 SUMO/deSUMOylation in cerebral ischemia-reperfusion injury.
Chen X, Yang T, Zhou Y, Mei Z, Zhang W
CNS neuroscience & therapeutics 2024 Apr;30(4):e14725
CNS neuroscience & therapeutics 2024 Apr;30(4):e14725
Mitochondria-associated endoplasmic reticulum membranes tethering protein VAPB-PTPIP51 protects against ischemic stroke through inhibiting the activation of autophagy.
Li M, Zhang Y, Yu G, Gu L, Zhu H, Feng S, Xiong X, Jian Z
CNS neuroscience & therapeutics 2024 Apr;30(4):e14707
CNS neuroscience & therapeutics 2024 Apr;30(4):e14707
Schisandrin B Alleviates LPS Induced Mitochondrial Damage in C28I2 Cells.
Hu F, Hu W, Xu H
The Journal of membrane biology 2024 Apr;257(1-2):107-114
The Journal of membrane biology 2024 Apr;257(1-2):107-114
Excessive processing and acetylation of OPA1 aggravate age-related hearing loss via the dysregulation of mitochondrial dynamics.
Zhang A, Pan Y, Wang H, Ding R, Zou T, Guo D, Shen Y, Ji P, Huang W, Wen Q, Wang Q, Hu H, Wu J, Xiang M, Ye B
Aging cell 2024 Apr;23(4):e14091
Aging cell 2024 Apr;23(4):e14091
The NLRX1-SLC39A7 complex orchestrates mitochondrial dynamics and mitophagy to rejuvenate intervertebral disc by modulating mitochondrial Zn(2+) trafficking.
Song Y, Liang H, Li G, Ma L, Zhu D, Zhang W, Tong B, Li S, Gao Y, Wu X, Zhang Y, Feng X, Wang K, Yang C
Autophagy 2024 Apr;20(4):809-829
Autophagy 2024 Apr;20(4):809-829
Moderate replacement of fish oil with palmitic acid-stimulated mitochondrial fusion promotes β-oxidation by Mfn2 interacting with Cpt1α via its GTPase-domain.
Song YF, Wang LJ, Luo Z, Hogstrand C, Lai XH, Zheng FF
The Journal of nutritional biochemistry 2024 Apr;126:109559
The Journal of nutritional biochemistry 2024 Apr;126:109559
Fufang Luohanguo Qingfei granules reduces influenza virus susceptibility via MAVS-dependent type I interferon antiviral signaling.
Lu YH, Wang M, Lin JQ, Wang MY, Zhou LY, He SH, Yi YT, Wei X, Huang QJ, Su ZH, Yang J, Guo HW, He RR, Luo Z
Journal of ethnopharmacology 2024 Apr 24;324:117780
Journal of ethnopharmacology 2024 Apr 24;324:117780
Phosphoglycerate mutase 5 exacerbates liver ischemia-reperfusion injury by activating mitochondrial fission.
Tang H, Yu Q, Chen X, Zhang J, Guo D, Guo W, Zhang S, Shi X
Scientific reports 2024 Apr 12;14(1):8535
Scientific reports 2024 Apr 12;14(1):8535
Icaritin with autophagy/mitophagy inhibitors synergistically enhances anticancer efficacy and apoptotic effects through PINK1/Parkin-mediated mitophagy in hepatocellular carcinoma.
Luo P, An Y, He J, Xing X, Zhang Q, Liu X, Chen Y, Yuan H, Chen J, Wong YK, Huang J, Gong Z, Du Q, Xiao W, Wang J
Cancer letters 2024 Apr 10;587:216621
Cancer letters 2024 Apr 10;587:216621
LonP1 Links Mitochondria-ER Interaction to Regulate Heart Function.
Li Y, Huang D, Jia L, Shangguan F, Gong S, Lan L, Song Z, Xu J, Yan C, Chen T, Tan Y, Liu Y, Huang X, Suzuki CK, Yang Z, Yang G, Lu B
Research (Washington, D.C.) 2023;6:0175
Research (Washington, D.C.) 2023;6:0175
Electroacupuncture Ameliorates Depression-Like Behaviors in Post-Stroke Rats via Activating AMPK-Mediated Mitochondrial Function.
Ding Z, Gao J, Feng Y, Wang M, Zhao H, Wu R, Zheng X, Feng X, Lai M
Neuropsychiatric disease and treatment 2023;19:2657-2671
Neuropsychiatric disease and treatment 2023;19:2657-2671
ShenQiWan ameliorates renal injury in type 2 diabetic mice by modulating mitochondrial fusion and endoplasmic reticulum stress.
Xiong W, Feng J, Liu Y, Liu J, Fu L, Wang Q, Li X, Li S
Frontiers in pharmacology 2023;14:1265551
Frontiers in pharmacology 2023;14:1265551
Growth hormone remodels the 3D-structure of the mitochondria of inflammatory macrophages and promotes metabolic reprogramming.
Soler Palacios B, Villares R, Lucas P, Rodríguez-Frade JM, Cayuela A, Piccirillo JG, Lombardía M, Delgado Gestoso D, Fernández-García M, Risco C, Barbas C, Corrales F, Sorzano COS, Martínez-Martín N, Conesa JJ, Iborra FJ, Mellado M
Frontiers in immunology 2023;14:1200259
Frontiers in immunology 2023;14:1200259
Blockage of S100A8/A9 ameliorates septic nephropathy in mice.
Shi W, Wan TT, Li HH, Guo SB
Frontiers in pharmacology 2023;14:1172356
Frontiers in pharmacology 2023;14:1172356
Exercise intervention improves mitochondrial quality in non-alcoholic fatty liver disease zebrafish.
Zou YY, Tang XB, Chen ZL, Liu B, Zheng L, Song MY, Xiao Q, Zhou ZQ, Peng XY, Tang CF
Frontiers in endocrinology 2023;14:1162485
Frontiers in endocrinology 2023;14:1162485
Investigating the effect of dehydromiltirone on septic AKI using a network pharmacology method, molecular docking, and experimental validation.
Chen S, Wang Y, Liu Y, Bai L, Li F, Wu Y, Xie X, Zhang N, Zeng C, Zhang L, Wang X
Frontiers in pharmacology 2023;14:1145675
Frontiers in pharmacology 2023;14:1145675
Menaquinone-4 prevents medication-related osteonecrosis of the jaw through the SIRT1 signaling-mediated inhibition of cellular metabolic stresses-induced osteoblast apoptosis.
Cui Y, Zhang W, Yang P, Zhu S, Luo S, Li M
Free radical biology & medicine 2023 Sep;206:33-49
Free radical biology & medicine 2023 Sep;206:33-49
Aerobic exercise enhances mitochondrial homeostasis to counteract D-galactose-induced sarcopenia in zebrafish.
Chen ZL, Guo C, Zou YY, Feng C, Yang DX, Sun CC, Wen W, Jian ZJ, Zhao Z, Xiao Q, Zheng L, Peng XY, Zhou ZQ, Tang CF
Experimental gerontology 2023 Sep;180:112265
Experimental gerontology 2023 Sep;180:112265
Loss and recovery of myocardial mitochondria in mice under different tail suspension time: Apoptosis and mitochondrial fission, fusion and autophagy.
Wang Z, Wang XC, Chen YF, Wang CL, Chen L, Jiang MY, Liu XW, Zhang XX, Feng YZ, Xu JH
Experimental physiology 2023 Sep;108(9):1189-1202
Experimental physiology 2023 Sep;108(9):1189-1202
UBQLN2 and HSP70 participate in Parkin-mediated mitophagy by facilitating outer mitochondrial membrane rupture.
Ma Q, Xin J, Peng Q, Li N, Sun S, Hou H, Ma G, Wang N, Zhang L, Tam KY, Dussmann H, Prehn JH, Wang H, Ying Z
EMBO reports 2023 Sep 6;24(9):e55859
EMBO reports 2023 Sep 6;24(9):e55859
Mitophagy disorder mediates cardiac deterioration induced by severe hypoglycemia in diabetic mice.
Huang C, Huang L, Huang Q, Lin L, Wang L, Wu Y, Wu K, Gao R, Liu X, Liu X, Qi L, Liu L
Molecular and cellular endocrinology 2023 Sep 15;575:111994
Molecular and cellular endocrinology 2023 Sep 15;575:111994
Mitochondrial miR-12294-5p regulated copper-induced mitochondrial oxidative stress and mitochondrial quality control imbalance by targeted inhibition of CISD1 in chicken livers.
Zhong G, Li Y, Li L, Huo Y, Zhang W, Li T, Ma F, Liao J, Li Y, Zhang H, Guo J, Pan J, Yu W, Hu L, Tang Z
Journal of hazardous materials 2023 Sep 15;458:131908
Journal of hazardous materials 2023 Sep 15;458:131908
Nuclear erythroid 2-related factor 2 protects against reactive oxygen species -induced preterm premature rupture of membranes through regulation of mitochondria†.
Zhang X, He X, Wei L, He Y, Li Y, Wang Y, Li C
Biology of reproduction 2023 Sep 12;109(3):330-339
Biology of reproduction 2023 Sep 12;109(3):330-339
DMT1 differentially regulates mitochondrial complex activities to reduce glutathione loss and mitigate ferroptosis.
Tan Q, Zhang X, Li S, Liu W, Yan J, Wang S, Cui F, Li D, Li J
Free radical biology & medicine 2023 Oct;207:32-44
Free radical biology & medicine 2023 Oct;207:32-44
Histone deacetylase inhibitor pracinostat suppresses colorectal cancer by inducing CDK5-Drp1 signaling-mediated peripheral mitofission.
Liang XL, Ouyang L, Yu NN, Sun ZH, Gui ZK, Niu YL, He QY, Zhang J, Wang Y
Journal of pharmaceutical analysis 2023 Oct;13(10):1168-1182
Journal of pharmaceutical analysis 2023 Oct;13(10):1168-1182
Scorpion venom heat-resistant peptide alleviates mitochondrial dynamics imbalance induced by PM(2.5) exposure by downregulating the PGC-1α/SIRT3 signaling pathway.
Huang L, Xu J, Duan K, Bao T, Cheng Y, Zhang H, Zhang Y, Lin Y, Li F
Toxicology research 2023 Oct;12(5):756-764
Toxicology research 2023 Oct;12(5):756-764
MicroRNA-129-1-3p attenuates autophagy-dependent cell death by targeting MCU in granulosa cells of laying hens under H(2)O(2)-induced oxidative stress.
Zhu M, Yan M, Chen J, Li H, Zhang Y
Poultry science 2023 Oct;102(10):103006
Poultry science 2023 Oct;102(10):103006
Polydatin improves vascular endothelial function by maintaining mitochondrial homeostasis under high glucose conditions.
Shah W, Zhao Q, Wang S, Zhang M, Ma H, Guan Y, Zhang Y, Liu Y, Zhu C, Wang S, Zhang X, Dong J, Ma H
Scientific reports 2023 Oct 2;13(1):16550
Scientific reports 2023 Oct 2;13(1):16550
The mitochondrial fusion-associated protein MFN2 can be used as a novel prognostic molecule for clear cell renal cell carcinoma.
Zhang B, Han D, Yang L, He Y, Yang S, Wang H, Zhang X, Du Y, Xiong W, Ha H, Shang P
BMC cancer 2023 Oct 16;23(1):986
BMC cancer 2023 Oct 16;23(1):986
TCH-165 attenuates cardiac ischaemia/reperfusion injury by balancing mitochondrial dynamics via increasing proteasome activity.
Gao J, Su HX, Li PB, Shi KN, Li HH
European journal of pharmacology 2023 Oct 15;957:176011
European journal of pharmacology 2023 Oct 15;957:176011
Down-regulation of the mitochondrial fusion protein Opa1/Mfn2 promotes cardiomyocyte hypertrophy in Su5416/hypoxia-induced pulmonary hypertension rats.
Luo F, Fu M, Wang T, Qi Y, Zhong X, Li D, Liu B
Archives of biochemistry and biophysics 2023 Oct 1;747:109743
Archives of biochemistry and biophysics 2023 Oct 1;747:109743
Lycorine promotes IDH1 acetylation to induce mitochondrial dynamics imbalance in colorectal cancer cells.
Zhuo FF, Li L, Liu TT, Liang XM, Yang Z, Zheng YZ, Luo QW, Lu JH, Liu D, Zeng KW, Tu PF
Cancer letters 2023 Oct 1;573:216364
Cancer letters 2023 Oct 1;573:216364
Endoplasmic reticulum stress induced by turbulence of mitochondrial fusion and fission was involved in stressed cardiomyocyte injury.
Zhang S, Li Y, Zhu W, Zhang L, Lei L, Tian X, Chen K, Shi W, Cong B
Journal of cellular and molecular medicine 2023 Nov;27(21):3313-3325
Journal of cellular and molecular medicine 2023 Nov;27(21):3313-3325
High-fat stimulation induces atrial neural remodeling by reducing NO production via the CRIF1/eNOS/P21 axi.
Zhang A, Li H, Song Q, Cui Y, Zhang Y, Wang X, Li Z, Hou Y
Lipids in health and disease 2023 Nov 6;22(1):189
Lipids in health and disease 2023 Nov 6;22(1):189
LPGAT1 controls MEGDEL syndrome by coupling phosphatidylglycerol remodeling with mitochondrial transport.
Sun H, Zhang J, Ye Q, Jiang T, Liu X, Zhang X, Zeng F, Li J, Zheng Y, Han X, Su C, Shi Y
Cell reports 2023 Nov 28;42(11):113214
Cell reports 2023 Nov 28;42(11):113214
Mitoguardin 1 and 2 promote granulosa cell proliferation by activating AKT and regulating the Hippo-YAP1 signaling pathway.
Yan MQ, Zhu BH, Liu XH, Yang YM, Duan XY, Wang Y, Sun H, Feng M, Li T, Liu XM
Cell death & disease 2023 Nov 27;14(11):779
Cell death & disease 2023 Nov 27;14(11):779
CCDC127 regulates lipid droplet homeostasis by enhancing mitochondria-ER contacts.
Xia Y, Zhang Y, Sun Y, He L
Biochemical and biophysical research communications 2023 Nov 26;683:149116
Biochemical and biophysical research communications 2023 Nov 26;683:149116
In vivo imaging of mitochondrial DNA mutations using an integrated nano Cas12a sensor.
Li Y, Wu Y, Xu R, Guo J, Quan F, Zhang Y, Huang D, Pei Y, Gao H, Liu W, Liu J, Zhang Z, Deng R, Shi J, Zhang K
Nature communications 2023 Nov 24;14(1):7722
Nature communications 2023 Nov 24;14(1):7722
Disturbed hippocampal histidine metabolism contributes to cognitive impairment induced by recurrent nonsevere hypoglycemia in diabetes.
Wu K, Xie W, Chen Z, Zhou L, Wang L, Zhou Y, Liu L
Biochemical and biophysical research communications 2023 Nov 19;682:325-334
Biochemical and biophysical research communications 2023 Nov 19;682:325-334
Low-dose atorvastatin protects skeletal muscle mitochondria in high-fat diet-fed mice with mitochondrial autophagy inhibition and fusion enhancement.
Zheng P, Zhang Q, Ma W, Hu R, Gu Y, Bian Z, Yang D, Chen X, Wu H
European journal of pharmacology 2023 Nov 15;959:176085
European journal of pharmacology 2023 Nov 15;959:176085
AdipoRon mitigates tau pathology and restores mitochondrial dynamics via AMPK-related pathway in a mouse model of Alzheimer's disease.
Wang C, Chang Y, Zhu J, Wu Y, Jiang X, Zheng S, Li G, Ma R
Experimental neurology 2023 May;363:114355
Experimental neurology 2023 May;363:114355
miR-27a-3p relieves heat stress-induced mitochondrial damage and aberrant milk protein synthesis through MEK/ERK pathway in BMECs.
Wang Y, Wu J, Xia SW, Zhao F, Ding Q, Ye XM, Zhong JF, Chen KL, Wang HL
Cell stress & chaperones 2023 May;28(3):265-274
Cell stress & chaperones 2023 May;28(3):265-274
Differentiation-inducing factor 1 activates cofilin through pyridoxal phosphatase and AMP-activated protein kinase, resulting in mitochondrial fission.
Inoue T, Miura K, Han R, Seto-Tetsuo F, Arioka M, Igawa K, Tomooka K, Sasaguri T
Journal of pharmacological sciences 2023 May;152(1):39-49
Journal of pharmacological sciences 2023 May;152(1):39-49
High uric acid aggravates apoptosis of lung epithelial cells induced by cigarette smoke extract through downregulating PRDX2 in chronic obstructive pulmonary disease.
Dong Y, Han F, Su Y, Sun B, Zhao W, Pan C
International immunopharmacology 2023 May;118:110056
International immunopharmacology 2023 May;118:110056
Mitochondrial dynamics define muscle fiber type by modulating cellular metabolic pathways.
Yasuda T, Ishihara T, Ichimura A, Ishihara N
Cell reports 2023 May 30;42(5):112434
Cell reports 2023 May 30;42(5):112434
QiShenYiQi dripping pill alleviates myocardial ischemia-induced ferroptosis via improving mitochondrial dynamical homeostasis and biogenesis.
Wu L, Fan Z, Gu L, Liu J, Cui Z, Yu B, Kou J, Li F
Journal of ethnopharmacology 2023 May 23;308:116282
Journal of ethnopharmacology 2023 May 23;308:116282
Pathological convergence of APP and SNCA deficiency in hippocampal degeneration of young rats.
Wang Y, Miao Z, Xu C, Cai Y, Yang Y, Hu Y, Zhao M, Shao Y, Li Z, Chen J, Chen S, Wang L
Cell death & disease 2023 May 13;14(5):325
Cell death & disease 2023 May 13;14(5):325
Acacetin inhibits myocardial mitochondrial dysfunction by activating PI3K/AKT in SHR rats fed with fructose.
Yuan P, Zhang Q, Fu Y, Hou Y, Gao L, Wei Y, Feng W, Zheng X
Journal of natural medicines 2023 Mar;77(2):262-275
Journal of natural medicines 2023 Mar;77(2):262-275
SZC-6, a small-molecule activator of SIRT3, attenuates cardiac hypertrophy in mice.
Li ZY, Lu GQ, Lu J, Wang PX, Zhang XL, Zou Y, Liu PQ
Acta pharmacologica Sinica 2023 Mar;44(3):546-560
Acta pharmacologica Sinica 2023 Mar;44(3):546-560
Mitofusin-2 mediates cannabidiol-induced neuroprotection against cerebral ischemia in rats.
Xu BT, Li MF, Chen KC, Li X, Cai NB, Xu JP, Wang HT
Acta pharmacologica Sinica 2023 Mar;44(3):499-512
Acta pharmacologica Sinica 2023 Mar;44(3):499-512
miR-124-3p improves mitochondrial function of renal tubular epithelial cells in db/db mice.
Liang L, Wo C, Yuan Y, Cao H, Tan W, Zhou X, Wang D, Chen R, Shi M, Zhang F, Xiao Y, Liu L, Zhou Y, Zhang T, Wang Y, Guo B
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2023 Mar;37(3):e22794
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2023 Mar;37(3):e22794
HC067047 as a potent TRPV4 inhibitor repairs endotoxemia colonic injury.
Chen L, Mao M, Liu D, Liu W, Wang Y, Xie L, Deng Y, Lin Y, Xu Y, Zhong X, Cao W
International immunopharmacology 2023 Mar;116:109648
International immunopharmacology 2023 Mar;116:109648
Mitoguardin2 Is Associated With Hyperandrogenism and Regulates Steroidogenesis in Human Ovarian Granulosa Cells.
Yan MQ, Wang Y, Wang Z, Liu XH, Yang YM, Duan XY, Sun H, Liu XM
Journal of the Endocrine Society 2023 Mar 6;7(5):bvad034
Journal of the Endocrine Society 2023 Mar 6;7(5):bvad034
TREM-1 triggers necroptosis of macrophages through mTOR-dependent mitochondrial fission during acute lung injury.
Zhong WJ, Zhang J, Duan JX, Zhang CY, Ma SC, Li YS, Yang NS, Yang HH, Xiong JB, Guan CX, Jiang ZX, You ZJ, Zhou Y
Journal of translational medicine 2023 Mar 6;21(1):179
Journal of translational medicine 2023 Mar 6;21(1):179
Macrophage Inactivation by Small Molecule Wedelolactone via Targeting sEH for the Treatment of LPS-Induced Acute Lung Injury.
Zhang J, Zhang M, Huo XK, Ning J, Yu ZL, Morisseau C, Sun CP, Hammock BD, Ma XC
ACS central science 2023 Mar 22;9(3):440-456
ACS central science 2023 Mar 22;9(3):440-456
MFN1 augmentation prevents retinal degeneration in a Charcot-Marie-Tooth type 2A mouse model.
Shahin S, Lu B, Zhou Y, Xu H, Chetsawang J, Baloh RH, Wang S
iScience 2023 Mar 17;26(3):106270
iScience 2023 Mar 17;26(3):106270
Ketogenic diets composed of long-chain and medium-chain fatty acids induce cardiac fibrosis in mice.
Sternberg F, Sternberg C, Dunkel A, Beikbaghban T, Gregor A, Szarzynski A, Somoza V, Walter I, Duszka K, Kofler B, Pohl EE
Molecular metabolism 2023 Jun;72:101711
Molecular metabolism 2023 Jun;72:101711
SS-31 alleviated nociceptive responses and restored mitochondrial function in a headache mouse model via Sirt3/Pgc-1α positive feedback loop.
Shan Z, Wang Y, Qiu T, Zhou Y, Zhang Y, Hu L, Zhang L, Liang J, Ding M, Fan S, Xiao Z
The journal of headache and pain 2023 Jun 5;24(1):65
The journal of headache and pain 2023 Jun 5;24(1):65
Endothelial progenitor cell-derived exosomes inhibit pulmonary artery smooth muscle cell in vitro proliferation and resistance to apoptosis by modulating the Mitofusin-2 and Ras-Raf-ERK1/2 signaling pathway.
Liu P, Gao S, Li Z, Pan S, Luo G, Ji Z
European journal of pharmacology 2023 Jun 15;949:175725
European journal of pharmacology 2023 Jun 15;949:175725
High-fat diet causes mitochondrial damage and downregulation of mitofusin-2 and optic atrophy-1 in multiple organs.
Zheng P, Ma W, Gu Y, Wu H, Bian Z, Liu N, Yang D, Chen X
Journal of clinical biochemistry and nutrition 2023 Jul;73(1):61-76
Journal of clinical biochemistry and nutrition 2023 Jul;73(1):61-76
Daytime-restricted feeding enhances running endurance without prior exercise in mice.
Xin H, Huang R, Zhou M, Chen J, Zhang J, Zhou T, Ji S, Liu X, Tian H, Lam SM, Bao X, Li L, Tong S, Deng F, Shui G, Zhang Z, Wong CCL, Li MD
Nature metabolism 2023 Jul;5(7):1236-1251
Nature metabolism 2023 Jul;5(7):1236-1251
Hydrogen sulfide alleviates mitochondrial damage and ferroptosis by regulating OPA3-NFS1 axis in doxorubicin-induced cardiotoxicity.
Wang Y, Ying X, Wang Y, Zou Z, Yuan A, Xiao Z, Geng N, Qiao Z, Li W, Lu X, Pu J
Cellular signalling 2023 Jul;107:110655
Cellular signalling 2023 Jul;107:110655
Mechanical force induces mitophagy-mediated anaerobic oxidation in periodontal ligament stem cells.
Zhang Z, Cui S, Fu Y, Wang J, Liu J, Wei F
Cellular & molecular biology letters 2023 Jul 21;28(1):57
Cellular & molecular biology letters 2023 Jul 21;28(1):57
A proximity labeling strategy enables proteomic analysis of inter-organelle membrane contacts.
Zhou M, Kong B, Zhang X, Xiao K, Lu J, Li W, Li M, Li Z, Ji W, Hou J, Xu T
iScience 2023 Jul 21;26(7):107159
iScience 2023 Jul 21;26(7):107159
Imbalance in ALR ubiquitination accelerates the progression of nonalcoholic steatohepatitis to hepatocellular carcinoma.
Zheng M, Ai Z, Guo Y, Chen Y, Xie P, An W
Oncogene 2023 Jan;42(4):308-321
Oncogene 2023 Jan;42(4):308-321
Oligomeric CHMP7 mediates three-way ER junctions and ER-mitochondria interactions.
Chu Q, Wang J, Du Y, Zhou T, Shi A, Xiong J, Ji WK, Deng L
Cell death and differentiation 2023 Jan;30(1):94-110
Cell death and differentiation 2023 Jan;30(1):94-110
N-acetyl-L-cysteine alleviates FUNDC1-mediated mitophagy by regulating mitochondrial dynamics in type 1 diabetic nephropathy canine.
Ma F, Li H, Huo H, Han Q, Liao J, Zhang H, Li Y, Pan J, Hu L, Guo J, Tang Z
Life sciences 2023 Jan 15;313:121278
Life sciences 2023 Jan 15;313:121278
Polypropylene nanoplastic exposure leads to lung inflammation through p38-mediated NF-κB pathway due to mitochondrial damage.
Woo JH, Seo HJ, Lee JY, Lee I, Jeon K, Kim B, Lee K
Particle and fibre toxicology 2023 Jan 10;20(1):2
Particle and fibre toxicology 2023 Jan 10;20(1):2
Adaptive exhaustion during prolonged intermittent hypoxia causes dysregulated skeletal muscle protein homeostasis.
Attaway AH, Bellar A, Mishra S, Karthikeyan M, Sekar J, Welch N, Musich R, Singh SS, Kumar A, Menon A, King J, Langen R, Webster J, Scheraga RG, Rochon K, Mears J, Naga Prasad SV, Hatzoglou M, Chakraborty AA, Dasarathy S
The Journal of physiology 2023 Feb;601(3):567-606
The Journal of physiology 2023 Feb;601(3):567-606
Phosphodiesterase 4B activation exacerbates pulmonary hypertension induced by intermittent hypoxia by regulating mitochondrial injury and cAMP/PKA/p-CREB/PGC-1α signaling.
Pan Z, Wu X, Zhang X, Hu K
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2023 Feb;158:114095
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2023 Feb;158:114095
Honokiol alleviated neurodegeneration by reducing oxidative stress and improving mitochondrial function in mutant SOD1 cellular and mouse models of amyotrophic lateral sclerosis.
Zhou Y, Tang J, Lan J, Zhang Y, Wang H, Chen Q, Kang Y, Sun Y, Feng X, Wu L, Jin H, Chen S, Peng Y
Acta pharmaceutica Sinica. B 2023 Feb;13(2):577-597
Acta pharmaceutica Sinica. B 2023 Feb;13(2):577-597
PKM2-mediated neuronal hyperglycolysis enhances the risk of Parkinson's disease in diabetic rats.
Zhao Y, Wang Y, Wu Y, Tao C, Xu R, Chen Y, Qian L, Xu T, Lian X
Journal of pharmaceutical analysis 2023 Feb;13(2):187-200
Journal of pharmaceutical analysis 2023 Feb;13(2):187-200
Osthole: A potential AMPK agonist that inhibits NLRP3 inflammasome activation by regulating mitochondrial homeostasis for combating rheumatoid arthritis.
Jiang X, Lu Z, Zhang Q, Yu J, Han D, Liu J, Li P, Li F
Phytomedicine : international journal of phytotherapy and phytopharmacology 2023 Feb;110:154640
Phytomedicine : international journal of phytotherapy and phytopharmacology 2023 Feb;110:154640
Mitochondrial Transfer Regulates Cell Fate Through Metabolic Remodeling in Osteoporosis.
Cai W, Zhang J, Yu Y, Ni Y, Wei Y, Cheng Y, Han L, Xiao L, Ma X, Wei H, Ji Y, Zhang Y
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2023 Feb;10(4):e2204871
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2023 Feb;10(4):e2204871
MiR-130a-3p regulates FUNDC1-mediated mitophagy by targeting GJA1 in myocardial ischemia/reperfusion injury.
Yan Y, Tian LY, Jia Q, Han Y, Tian Y, Chen HN, Cui SJ, Xi J, Yao YM, Zhao XJ
Cell death discovery 2023 Feb 25;9(1):77
Cell death discovery 2023 Feb 25;9(1):77
Identification and validation of a novel prognostic signature based on mitochondria and oxidative stress related genes for glioblastoma.
Tong S, Xia M, Xu Y, Sun Q, Ye L, Yuan F, Wang Y, Cai J, Ye Z, Tian D
Journal of translational medicine 2023 Feb 22;21(1):136
Journal of translational medicine 2023 Feb 22;21(1):136
METTL14-dependent maturation of pri-miR-17 regulates mitochondrial homeostasis and induces chemoresistance in colorectal cancer.
Sun K, Chen L, Li Y, Huang B, Yan Q, Wu C, Lai Q, Fang Y, Cai J, Liu Y, Chen J, Wang X, Zhu Y, Dong S, Tan J, Li A, Liu S, Zhang Y
Cell death & disease 2023 Feb 21;14(2):148
Cell death & disease 2023 Feb 21;14(2):148
Stomatin-like protein 2 deficiency exacerbates adverse cardiac remodeling.
Hu Y, Jiang H, Xu Y, Chen G, Fan R, Zhou Y, Liu Y, Yao Y, Liu R, Chen W, Zhang K, Chen X, Wang R, Qiu Z
Cell death discovery 2023 Feb 14;9(1):63
Cell death discovery 2023 Feb 14;9(1):63
SIRT3-dependent mitochondrial redox homeostasis mitigates CHK1 inhibition combined with gemcitabine treatment induced cardiotoxicity in hiPSC-CMs and mice.
Chen JW, Shan TK, Wei TW, Jiang QQ, Du C, Gu LF, Yang TT, Zhou LH, Wang SB, Bao YL, Wang H, Ji Y, Xie LP, Gu AH, Sun CQ, Wang QM, Wang LS
Archives of toxicology 2023 Dec;97(12):3209-3226
Archives of toxicology 2023 Dec;97(12):3209-3226
Nogo-B mediates endothelial oxidative stress and inflammation to promote coronary atherosclerosis in pressure-overloaded mouse hearts.
Zhang Y, Li JJ, Xu R, Wang XP, Zhao XY, Fang Y, Chen YP, Ma S, Di XH, Wu W, She G, Pang ZD, Wang YD, Zhang X, Xie W, Deng XL, Du XJ, Zhang Y
Redox biology 2023 Dec;68:102944
Redox biology 2023 Dec;68:102944
BNIP3 overexpression may promote myeloma cell apoptosis by enhancing sensitivity to bortezomib via the p38 MAPK pathway.
Xiao P, Chen X, Dong Z, Fan W, Chen Y, Su J, Wang Q, Ma L
Hematology (Amsterdam, Netherlands) 2023 Dec;28(1):2231739
Hematology (Amsterdam, Netherlands) 2023 Dec;28(1):2231739
Zearalenone promotes porcine ESCs apoptosis by enhancing Drp1-mediated mitochondrial fragmentation and activating the JNK pathway.
Hai S, Zhao J, Chen C, Wang C, Ma L, Rahman SU, Zhao C, Feng S, Wu J, Wang X
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 2023 Dec;182:114110
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 2023 Dec;182:114110
Effects of dapagliflozin monotherapy and combined aerobic exercise on skeletal muscle mitochondrial quality control and insulin resistance in type 2 diabetes mellitus rats.
Zhang L, Lin H, Yang X, Shi J, Sheng X, Wang L, Li T, Quan H, Zhai X, Li W
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2023 Dec 31;169:115852
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2023 Dec 31;169:115852
Ramelteon attenuates renal ischemia and reperfusion injury through reducing mitochondrial fission and fusion and inflammation.
Chen P, Liu W, Wei Y
Translational andrology and urology 2023 Dec 31;12(12):1859-1870
Translational andrology and urology 2023 Dec 31;12(12):1859-1870
The Binding of HSPA8 and Mitochondrial ALDH2 Mediates Oxygen-Glucose Deprivation-Induced Fibroblast Senescence.
Hui W, Song T, Yu L, Chen X
Antioxidants (Basel, Switzerland) 2023 Dec 25;13(1)
Antioxidants (Basel, Switzerland) 2023 Dec 25;13(1)
Cirsiliol induces autophagy and mitochondrial apoptosis through the AKT/FOXO1 axis and influences methotrexate resistance in osteosarcoma.
Luo M, Su Z, Gao H, Tan J, Liao R, Yang J, Lin L
Journal of translational medicine 2023 Dec 12;21(1):907
Journal of translational medicine 2023 Dec 12;21(1):907
Ubiquitination of Ku70 by Parkin promotes apoptosis of lens epithelial cells.
Zhang W, Wu A, Zhang G, Ding X, Kang L, Zhou T, Ji M, Guan H
The FEBS journal 2023 Aug;290(15):3828-3842
The FEBS journal 2023 Aug;290(15):3828-3842
Phospholipase A2-activating protein induces mitophagy through anti-apoptotic MCL1-mediated NLRX1 oligomerization.
Zheng Z, Han L, Li Y, Chen Z, Yang W, Liu C, Tao M, Jiang Y, Ke X, Liu Y, Guo X
Biochimica et biophysica acta. Molecular cell research 2023 Aug;1870(6):119487
Biochimica et biophysica acta. Molecular cell research 2023 Aug;1870(6):119487
Advanced oxidation protein products induce Paneth cells defects by endoplasmic reticulum stress in Crohn's disease.
Shi J, Wang W, Sun S, Xu X, Fei J, Zhou Q, Qin C, Ou S, Wu F, Wu FT, Xu T, Bai L, Xie F
iScience 2023 Aug 18;26(8):107312
iScience 2023 Aug 18;26(8):107312
Diosgenin Targets CaMKK2 to Alleviate Type II Diabetic Nephropathy through Improving Autophagy, Mitophagy and Mitochondrial Dynamics.
Zhong Y, Jin R, Luo R, Liu J, Ren L, Zhang Y, Shan Z, Peng X
Nutrients 2023 Aug 11;15(16)
Nutrients 2023 Aug 11;15(16)
Correction: Tang et al. Vitamin K2 Modulates Mitochondrial Dysfunction Induced by 6-Hydroxydopamine in SH-SY5Y Cells via Mitochondrial Quality-Control Loop. Nutrients 2022, 14, 1504.
Tang H, Zheng Z, Wang H, Wang L, Zhao G, Wang P
Nutrients 2023 Aug 11;15(16)
Nutrients 2023 Aug 11;15(16)
Aristolochic acid I exposure triggers ovarian dysfunction by activating NLRP3 inflammasome and affecting mitochondrial homeostasis.
Sun MX, Qiao FX, Xu ZR, Liu YC, Xu CL, Wang HL, Qi ZQ, Liu Y
Free radical biology & medicine 2023 Aug 1;204:313-324
Free radical biology & medicine 2023 Aug 1;204:313-324
Mitochondria-associated endoplasmic reticulum membranes dysfunction contributes to PARP-1-dependent cell death under oxidative stress in retinal precursor cells.
Yang Y, Wu J, Lu W, Dai Y, Zhang Y, Sun X
Journal of biochemical and molecular toxicology 2023 Apr;37(4):e23303
Journal of biochemical and molecular toxicology 2023 Apr;37(4):e23303
Inhibition of mitochondrial VDAC1 oligomerization alleviates apoptosis and necroptosis of retinal neurons following OGD/R injury.
Wan H, Yan YD, Hu XM, Shang L, Chen YH, Huang YX, Zhang Q, Yan WT, Xiong K
Annals of anatomy = Anatomischer Anzeiger : official organ of the Anatomische Gesellschaft 2023 Apr;247:152049
Annals of anatomy = Anatomischer Anzeiger : official organ of the Anatomische Gesellschaft 2023 Apr;247:152049
Small molecule agonist of mitochondrial fusion repairs mitochondrial dysfunction.
Guo Y, Zhang H, Yan C, Shen B, Zhang Y, Guo X, Sun S, Yu F, Yan J, Liu R, Zhang Q, Zhang D, Liu H, Liu Y, Zhang Y, Li W, Qin J, Lv H, Wang Z, Yuan Y, Yang JF, Zhong YT, Gao S, Zhou B, Liu L, Kong D, Hao X, Hu J, Chen Q
Nature chemical biology 2023 Apr;19(4):468-477
Nature chemical biology 2023 Apr;19(4):468-477
Molybdenum and Cadmium Co-induce Mitochondrial Quality Control Disorder via FUNDC1-Mediated Mitophagy in Sheep Kidney.
Wu Y, Yang F, Zhou G, Wang Q, Xing C, Bai H, Yi X, Xiong Z, Yang S, Cao H
Frontiers in veterinary science 2022;9:842259
Frontiers in veterinary science 2022;9:842259
Administration of miR-195 Inhibitor Enhances Memory Function Through Improving Synaptic Degradation and Mitochondrial Dysfunction of the Hippocampal Neurons in SAMP8 Mice.
Gao Z, Zhang R, Jiang L, Zhou H, Wang Q, Ma Y, Zhang D, Qin Y, Tian P, Zhang N, Shi Z, Xu S
Journal of Alzheimer's disease : JAD 2022;85(4):1495-1509
Journal of Alzheimer's disease : JAD 2022;85(4):1495-1509
Selenium Attenuates TBHP-Induced Apoptosis of Nucleus Pulposus Cells by Suppressing Mitochondrial Fission through Activating Nuclear Factor Erythroid 2-Related Factor 2.
Wang P, Zhang S, Liu W, Chen S, Lv X, Hu B, Shao Z
Oxidative medicine and cellular longevity 2022;2022:7531788
Oxidative medicine and cellular longevity 2022;2022:7531788
Dexmedetomidine Can Enhance PINK1/Parkin-Mediated Mitophagy in MPTP-Induced PD Mice Model by Activating AMPK.
Chen C, Chen Y, Liu T, Song D, Ma D, Cheng O
Oxidative medicine and cellular longevity 2022;2022:7511393
Oxidative medicine and cellular longevity 2022;2022:7511393
Blockage of Fibronectin 1 Ameliorates Myocardial Ischemia/Reperfusion Injury in Association with Activation of AMP-LKB1-AMPK Signaling Pathway.
Zhang YL, Li PB, Han X, Zhang B, Li HH
Oxidative medicine and cellular longevity 2022;2022:6196173
Oxidative medicine and cellular longevity 2022;2022:6196173
Change in Oxidative Stress and Mitochondrial Dynamics in Response to Elevated Cold-Inducible RNA-Binding Protein in Cardiac Surgery-Associated Acute Kidney Injury.
Zheng X, Fan Y, Li J, Ma T, Li Y, Wang Q, Yan Y, Liu W
Oxidative medicine and cellular longevity 2022;2022:3576892
Oxidative medicine and cellular longevity 2022;2022:3576892
Docosahexaenoic Acid Alleviates Brain Damage by Promoting Mitophagy in Mice with Ischaemic Stroke.
Sun E, Zhang J, Deng Y, Wang J, Wu Q, Chen W, Ma X, Chen S, Xiang X, Chen Y, Wu T, Yang Y, Chen B
Oxidative medicine and cellular longevity 2022;2022:3119649
Oxidative medicine and cellular longevity 2022;2022:3119649
Appropriate Dose of Dapagliflozin Improves Cardiac Outcomes by Normalizing Mitochondrial Fission and Reducing Cardiomyocyte Apoptosis After Acute Myocardial Infarction.
Fan ZG, Xu Y, Chen X, Ji MY, Ma GS
Drug design, development and therapy 2022;16:2017-2030
Drug design, development and therapy 2022;16:2017-2030
Cangfudaotan decoction inhibits mitochondria-dependent apoptosis of granulosa cells in rats with polycystic ovarian syndrome.
Jiang XL, Tai H, Xiao XS, Zhang SY, Cui SC, Qi SB, Hu DD, Zhang LN, Kuang JS, Meng XS, Li SM
Frontiers in endocrinology 2022;13:962154
Frontiers in endocrinology 2022;13:962154
Mfn2 is responsible for inhibition of the RIG-I/IRF7 pathway and activation of NLRP3 inflammasome in Seneca Valley virus-infected PK-15 cells to promote viral replication.
Deng H, Zhu S, Zhu L, Sun J, Ding Y, Li F, Jian Z, Zhao J, Deng L, Deng J, Deng Y, Guo H, Sun X, Lai SY, Tang H, Cui H, Ge LP, Xu Z
Frontiers in immunology 2022;13:955671
Frontiers in immunology 2022;13:955671
Intracellular Ca(2+) Signaling and Calcium Release-Activated Calcium Modulator ORAI1 Are Associated With CD4(+) T Lymphocytes in Dairy Cows.
Li M, Zhang B, Yin Y, Wen J, Wang J, He Y, Jiang Q, Loor JJ, Wang S, Yang W, Xu C
Frontiers in immunology 2022;13:835936
Frontiers in immunology 2022;13:835936
COA3 overexpression promotes non-small cell lung cancer metastasis by reprogramming glucose metabolism.
Lin H, Gao Y, Sun K, Zhang Q, Li Y, Chen M, Jin F
American journal of cancer research 2022;12(8):3662-3678
American journal of cancer research 2022;12(8):3662-3678
Non-invasive photobiomodulation treatment in an Alzheimer Disease-like transgenic rat model.
Yang L, Wu C, Parker E, Li Y, Dong Y, Tucker L, Brann DW, Lin HW, Zhang Q
Theranostics 2022;12(5):2205-2231
Theranostics 2022;12(5):2205-2231
PINK1-Dependent Mitophagy Reduced Endothelial Hyperpermeability and Cell Migration Capacity Under Simulated Microgravity.
Li C, Pan Y, Tan Y, Wang Y, Sun X
Frontiers in cell and developmental biology 2022;10:896014
Frontiers in cell and developmental biology 2022;10:896014
Scutellarin Protects Against Mitochondrial Reactive Oxygen Species-Dependent NLRP3 Inflammasome Activation to Attenuate Intervertebral Disc Degeneration.
Wang Z, Zhang P, Zhao Y, Yu F, Wang S, Liu K, Cheng X, Shi J, He Q, Xia Y, Cheng L
Frontiers in bioengineering and biotechnology 2022;10:883118
Frontiers in bioengineering and biotechnology 2022;10:883118
Mitoquinone mitigates paraquat-induced A549 lung epithelial cell injury by promoting MFN1/MFN2-mediated mitochondrial fusion.
Liu C, Sun Z, Wang M, Yang Z, Zhang W, Ren Y, Han X, Zhang B, Yao M, Nie S
Journal of biochemical and molecular toxicology 2022 Sep;36(9):e23127
Journal of biochemical and molecular toxicology 2022 Sep;36(9):e23127
Battery wastewater induces nephrotoxicity via disordering the mitochondrial dynamics.
Yi J, Liao J, Bai T, Wang B, Yangzom C, Ahmed Z, Mehmood K, Abbas RZ, Li Y, Tang Z, Zhang H
Chemosphere 2022 Sep;303(Pt 1):135018
Chemosphere 2022 Sep;303(Pt 1):135018
Gefitinib facilitates PINK1/Parkin-mediated mitophagy by enhancing mitochondrial recruitment of OPTN.
Li N, Sun S, Ma G, Hou H, Ma Q, Zhang L, Zhang Z, Wang H, Ying Z
Fundamental research 2022 Sep;2(5):807-816
Fundamental research 2022 Sep;2(5):807-816
Mannose inhibits the growth of prostate cancer through a mitochondrial mechanism.
Deng YL, Liu R, Cai ZD, Han ZD, Feng YF, Cai SH, Chen QB, Zhu JG, Zhong WD
Asian journal of andrology 2022 Sep-Oct;24(5):540-548
Asian journal of andrology 2022 Sep-Oct;24(5):540-548
Exposure to Benzo(a)pyrene damages mitochondrial function via suppressing mitochondrial melatonin receptors in ovarian corpus luteum during early pregnancy.
Yang J, Xu H, Gao R, Liu X, He J, Zhou M, Ding Y, Li F, Geng Y, Mu X, Liu T, Wang Y, Chen X
Chemico-biological interactions 2022 Sep 25;365:110085
Chemico-biological interactions 2022 Sep 25;365:110085
Polystyrene microplastics-induced cardiotoxicity in chickens via the ROS-driven NF-κB-NLRP3-GSDMD and AMPK-PGC-1α axes.
Zhang Y, Yin K, Wang D, Wang Y, Lu H, Zhao H, Xing M
The Science of the total environment 2022 Sep 20;840:156727
The Science of the total environment 2022 Sep 20;840:156727
Transient Receptor Potential Vanilloid Type 1 Protects Against Pressure Overload-Induced Cardiac Hypertrophy by Promoting Mitochondria-Associated Endoplasmic Reticulum Membranes.
Wang Y, Li X, Xu X, Qu X, Yang Y
Journal of cardiovascular pharmacology 2022 Sep 1;80(3):430-441
Journal of cardiovascular pharmacology 2022 Sep 1;80(3):430-441
Blocking exosomal secretion aggravates 1,4-benzoquinone-induced mitochondrial fission activated by the AMPK/MFF/Drp1 pathway in HL-60 cells.
Lu F, Zhang Q, Zhang M, Sun S, Yang X, Yan H
Journal of applied toxicology : JAT 2022 Oct;42(10):1618-1627
Journal of applied toxicology : JAT 2022 Oct;42(10):1618-1627
Mammary Fibrosis Tendency and Mitochondrial Adaptability in Dairy Cows with Mastitis.
Kan X, Hu G, Liu Y, Xu P, Huang Y, Cai X, Guo W, Fu S, Liu J
Metabolites 2022 Oct 28;12(11)
Metabolites 2022 Oct 28;12(11)
Jian-Pi-Yi-Shen decoction inhibits mitochondria-dependent granulosa cell apoptosis in a rat model of POF.
Jiang XL, Tai H, Kuang JS, Zhang JY, Cui SC, Lu YX, Qi SB, Zhang SY, Li SM, Chen JP, Meng XS
Aging 2022 Oct 27;14(20):8321-8345
Aging 2022 Oct 27;14(20):8321-8345
Renoprotective effect of Tanshinone IIA against kidney injury induced by ischemia-reperfusion in obese rats.
Tai H, Cui XZ, He J, Lan ZM, Li SM, Li LB, Yao SC, Jiang XL, Meng XS, Kuang JS
Aging 2022 Oct 20;14(20):8302-8320
Aging 2022 Oct 20;14(20):8302-8320
Dihydromyricetin contributes to weight loss via pro-browning mediated by mitochondrial fission in white adipose.
Xiong X, Xia M, Niu A, Zhang Y, Yin T, Huang Q
European journal of pharmacology 2022 Nov 15;935:175345
European journal of pharmacology 2022 Nov 15;935:175345
Down-regulating of MFN2 promotes vascular calcification via regulating RAS-RAF-ERK1/2 pathway.
Zhang WB, Feng SY, Xiao ZX, Qi YF, Zeng ZF, Chen H
International journal of cardiology 2022 Nov 1;366:11-18
International journal of cardiology 2022 Nov 1;366:11-18
SIRT4 Expression Ameliorates the Detrimental Effect of Heat Stress via AMPK/mTOR Signaling Pathway in BMECs.
Ding Q, Wang Y, Xia SW, Zhao F, Zhong JF, Wang HL, Chen KL
International journal of molecular sciences 2022 Nov 1;23(21)
International journal of molecular sciences 2022 Nov 1;23(21)
Gestational Intermittent Hypoxia Induces Mitochondrial Impairment in the Geniohyoid Muscle of Offspring Rats.
Wongkitikamjorn W, Hosomichi J, Wada E, Maeda H, Satrawaha S, Hong H, Hayashi YK, Yoshida KI, Ono T
Cureus 2022 May;14(5):e25088
Cureus 2022 May;14(5):e25088
A High-Fat Diet Induces Muscle Mitochondrial Dysfunction and Impairs Swimming Capacity in Zebrafish: A New Model of Sarcopenic Obesity.
Zou YY, Chen ZL, Sun CC, Yang D, Zhou ZQ, Xiao Q, Peng XY, Tang CF
Nutrients 2022 May 9;14(9)
Nutrients 2022 May 9;14(9)
PACS-2 Ameliorates Tubular Injury by Facilitating Endoplasmic Reticulum-Mitochondria Contact and Mitophagy in Diabetic Nephropathy.
Li C, Li L, Yang M, Yang J, Zhao C, Han Y, Zhao H, Jiang N, Wei L, Xiao Y, Liu Y, Xiong X, Xi Y, Luo S, Deng F, Chen W, Yuan S, Zhu X, Xiao L, Sun L
Diabetes 2022 May 1;71(5):1034-1050
Diabetes 2022 May 1;71(5):1034-1050
HSP70 attenuates compression-induced apoptosis of nucleus pulposus cells by suppressing mitochondrial fission via upregulating the expression of SIRT3.
Hu B, Wang P, Zhang S, Liu W, Lv X, Shi D, Zhao L, Liu H, Wang B, Chen S, Shao Z
Experimental & molecular medicine 2022 Mar;54(3):309-323
Experimental & molecular medicine 2022 Mar;54(3):309-323
Map, but not EspF, induces breast epithelial cell apoptosis through ERK/DRP-1 pathway.
Li Y, Zhu Y, Chu B, Liu N, Chen S, Wang J
Veterinary microbiology 2022 Mar;266:109367
Veterinary microbiology 2022 Mar;266:109367
Chicoric Acid Attenuated Renal Tubular Injury in HFD-Induced Chronic Kidney Disease Mice through the Promotion of Mitophagy via the Nrf2/PINK/Parkin Pathway.
Ding XQ, Jian TY, Gai YN, Niu GT, Liu Y, Meng XH, Li J, Lyu H, Ren BR, Chen J
Journal of agricultural and food chemistry 2022 Mar 9;70(9):2923-2935
Journal of agricultural and food chemistry 2022 Mar 9;70(9):2923-2935
Clueless/CLUH regulates mitochondrial fission by promoting recruitment of Drp1 to mitochondria.
Yang H, Sibilla C, Liu R, Yun J, Hay BA, Blackstone C, Chan DC, Harvey RJ, Guo M
Nature communications 2022 Mar 24;13(1):1582
Nature communications 2022 Mar 24;13(1):1582
Dioscin relieves diabetic nephropathy via suppressing oxidative stress and apoptosis, and improving mitochondrial quality and quantity control.
Zhong Y, Liu J, Sun D, Guo T, Yao Y, Xia X, Shi C, Peng X
Food & function 2022 Mar 21;13(6):3660-3673
Food & function 2022 Mar 21;13(6):3660-3673
Nephrotoxicity evaluation of 3-monochloropropane-1,2-diol exposure in Sprague-Dawley rats using data-independent acquisition-based quantitative proteomics analysis.
Jin C, Min F, Zhong Y, Sun D, Luo R, Liu Q, Peng X
Toxicology letters 2022 Mar 1;356:110-120
Toxicology letters 2022 Mar 1;356:110-120
Autophagy and mitochondrial dynamics contribute to the protective effect of diosgenin against 3-MCPD induced kidney injury.
Zhong Y, Sun D, Yao Y, Liu Q, Guo T, Wang X, Peng X
Chemico-biological interactions 2022 Mar 1;355:109850
Chemico-biological interactions 2022 Mar 1;355:109850
Caveolin-1 controls mitochondrial damage and ROS production by regulating fission - fusion dynamics and mitophagy.
Jiang Y, Krantz S, Qin X, Li S, Gunasekara H, Kim YM, Zimnicka A, Bae M, Ma K, Toth PT, Hu Y, Shajahan-Haq AN, Patel HH, Gentile S, Bonini MG, Rehman J, Liu Y, Minshall RD
Redox biology 2022 Jun;52:102304
Redox biology 2022 Jun;52:102304
A possible new activator of PI3K-Huayu Qutan Recipe alleviates mitochondrial apoptosis in obesity rats with acute myocardial infarction.
Tai H, Tong YJ, Yu R, Yu Y, Yao SC, Li LB, Liu Y, Cui XZ, Kuang JS, Meng XS, Jiang XL
Journal of cellular and molecular medicine 2022 Jun;26(12):3423-3445
Journal of cellular and molecular medicine 2022 Jun;26(12):3423-3445
Total flavonoids of Selaginella tamariscina (P.Beauv.) Spring ameliorates doxorubicin-induced cardiotoxicity by modulating mitochondrial dysfunction and endoplasmic reticulum stress via activating MFN2/PERK.
Gao L, Yuan P, Wei Y, Fu Y, Hou Y, Li P, Chen Y, Ruan Y, Zhou N, Zheng X, Feng W
Phytomedicine : international journal of phytotherapy and phytopharmacology 2022 Jun;100:154065
Phytomedicine : international journal of phytotherapy and phytopharmacology 2022 Jun;100:154065
Novel Thermosensitive Hydrogel Promotes Spinal Cord Repair by Regulating Mitochondrial Function.
Li Y, Yang L, Hu F, Xu J, Ye J, Liu S, Wang L, Zhuo M, Ran B, Zhang H, Ye J, Xiao J
ACS applied materials & interfaces 2022 Jun 8;14(22):25155-25172
ACS applied materials & interfaces 2022 Jun 8;14(22):25155-25172
SUMO2-mediated SUMOylation of SH3GLB1 promotes ionizing radiation-induced hypertrophic cardiomyopathy through mitophagy activation.
Gao A, Zou J, Mao Z, Zhou H, Zeng G
European journal of pharmacology 2022 Jun 5;924:174980
European journal of pharmacology 2022 Jun 5;924:174980
FUNDC2 promotes liver tumorigenesis by inhibiting MFN1-mediated mitochondrial fusion.
Li S, Han S, Zhang Q, Zhu Y, Zhang H, Wang J, Zhao Y, Zhao J, Su L, Li L, Zhou D, Ye C, Feng XH, Liang T, Zhao B
Nature communications 2022 Jun 17;13(1):3486
Nature communications 2022 Jun 17;13(1):3486
The mitochondrial protein Sideroflexin 3 (SFXN3) influences neurodegeneration pathways in vivo.
Ledahawsky LM, Terzenidou ME, Edwards R, Kline RA, Graham LC, Eaton SL, van der Hoorn D, Chaytow H, Huang YT, Groen EJN, Motyl AAL, Lamont DJ, Tokatlidis K, Wishart TM, Gillingwater TH
The FEBS journal 2022 Jul;289(13):3894-3914
The FEBS journal 2022 Jul;289(13):3894-3914
Urolithin A protects human dermal fibroblasts from UVA-induced photoaging through NRF2 activation and mitophagy.
Liu W, Yan F, Xu Z, Chen Q, Ren J, Wang Q, Chen L, Ying J, Liu Z, Zhao J, Qiu J, Zhang C, Jiang M, Xiang L
Journal of photochemistry and photobiology. B, Biology 2022 Jul;232:112462
Journal of photochemistry and photobiology. B, Biology 2022 Jul;232:112462
Selenium alleviates cadmium-induced aging via mitochondrial quality control in the livers of sheep.
Xiong Z, Yang F, Xu T, Yang Y, Wang F, Zhou G, Wang Q, Guo X, Xing C, Bai H, Chen J, Wu Y, Yang S, Cao H
Journal of inorganic biochemistry 2022 Jul;232:111818
Journal of inorganic biochemistry 2022 Jul;232:111818
LncRNA ANRIL mediates endothelial dysfunction through BDNF downregulation in chronic kidney disease.
Su H, Liu B, Chen H, Zhang T, Huang T, Liu Y, Wang C, Ma Q, Wang Q, Lv Z, Wang R
Cell death & disease 2022 Jul 29;13(7):661
Cell death & disease 2022 Jul 29;13(7):661
Chronic Hypoxia Inhibits Respiratory Complex IV Activity and Disrupts Mitochondrial Dynamics in the Fetal Guinea Pig Forebrain.
Quebedeaux TM, Song H, Giwa-Otusajo J, Thompson LP
Reproductive sciences (Thousand Oaks, Calif.) 2022 Jan;29(1):184-192
Reproductive sciences (Thousand Oaks, Calif.) 2022 Jan;29(1):184-192
Liraglutide Regulates Mitochondrial Quality Control System Through PGC-1α in a Mouse Model of Parkinson's Disease.
Wu P, Dong Y, Chen J, Guan T, Cao B, Zhang Y, Qi Y, Guan Z, Wang Y
Neurotoxicity research 2022 Feb;40(1):286-297
Neurotoxicity research 2022 Feb;40(1):286-297
Interfering with mitochondrial dynamics sensitizes glioblastoma multiforme to temozolomide chemotherapy.
Wang N, Huang R, Yang K, He Y, Gao Y, Dong D
Journal of cellular and molecular medicine 2022 Feb;26(3):893-912
Journal of cellular and molecular medicine 2022 Feb;26(3):893-912
Histone deacetylase inhibitors inhibit cervical cancer growth through Parkin acetylation-mediated mitophagy.
Sun X, Shu Y, Ye G, Wu C, Xu M, Gao R, Huang D, Zhang J
Acta pharmaceutica Sinica. B 2022 Feb;12(2):838-852
Acta pharmaceutica Sinica. B 2022 Feb;12(2):838-852
Attenuates of NAD(+) impair BMSC osteogenesis and fracture repair through OXPHOS.
Li B, Shi Y, Liu M, Wu F, Hu X, Yu F, Wang C, Ye L
Stem cell research & therapy 2022 Feb 22;13(1):77
Stem cell research & therapy 2022 Feb 22;13(1):77
Cdk5 Promotes Mitochondrial Fission via Drp1 Phosphorylation at S616 in Chronic Ethanol Exposure-Induced Cognitive Impairment.
Liu D, Li J, Rong X, Li J, Peng Y, Shen Q
Molecular neurobiology 2022 Dec;59(12):7075-7094
Molecular neurobiology 2022 Dec;59(12):7075-7094
Activation of FMS-like tyrosine kinase 3 protects against isoprenaline-induced cardiac hypertrophy by improving autophagy and mitochondrial dynamics.
Jiang X, Zhang K, Gao C, Ma W, Liu M, Guo X, Bao G, Han B, Hu H, Zhao Z
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2022 Dec;36(12):e22672
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2022 Dec;36(12):e22672
CEND1 deficiency induces mitochondrial dysfunction and cognitive impairment in Alzheimer's disease.
Xie W, Guo D, Li J, Yue L, Kang Q, Chen G, Zhou T, Wang H, Zhuang K, Leng L, Li H, Chen Z, Gao W, Zhang J
Cell death and differentiation 2022 Dec;29(12):2417-2428
Cell death and differentiation 2022 Dec;29(12):2417-2428
Spermidine Alleviates Intrauterine Hypoxia-Induced Offspring Newborn Myocardial Mitochondrial Damage in Rats by Inhibiting Oxidative Stress and Regulating Mitochondrial Quality Control.
Chai N, Zheng H, Zhang H, Li L, Yu X, Wang L, Bi X, Yang L, Niu T, Liu X, Zhao Y, Dong L
Iranian journal of pharmaceutical research : IJPR 2022 Dec;21(1):e133776
Iranian journal of pharmaceutical research : IJPR 2022 Dec;21(1):e133776
GABA regulates IL-1β production in macrophages.
Fu J, Han Z, Wu Z, Xia Y, Yang G, Yin Y, Ren W
Cell reports 2022 Dec 6;41(10):111770
Cell reports 2022 Dec 6;41(10):111770
Endosomal lipid signaling reshapes the endoplasmic reticulum to control mitochondrial function.
Jang W, Puchkov D, Samsó P, Liang Y, Nadler-Holly M, Sigrist SJ, Kintscher U, Liu F, Mamchaoui K, Mouly V, Haucke V
Science (New York, N.Y.) 2022 Dec 16;378(6625):eabq5209
Science (New York, N.Y.) 2022 Dec 16;378(6625):eabq5209
A pivotal role of selective autophagy in mitochondrial quality control: Implications for zinc oxide nanoparticles induced neurotoxicity.
Wang L, Duan Z, Liang M, Wang C, Liang T, Sun L, Yan C, Li Q, Liang T
Chemico-biological interactions 2022 Aug 25;363:110003
Chemico-biological interactions 2022 Aug 25;363:110003
Baicalein suppresses high glucose-induced inflammation and apoptosis in trophoblasts by targeting the miRNA-17-5p-Mfn1/2-NF-κB pathway.
Li J, Wang Y, Wu T, Li S, Sun YN, Liu ZH
Placenta 2022 Apr;121:126-136
Placenta 2022 Apr;121:126-136
Map of Enteropathogenic Escherichia coli Targets Mitochondria and Triggers DRP-1-Mediated Mitochondrial Fission and Cell Apoptosis in Bovine Mastitis.
Li Y, Zhu Y, Chu B, Liu N, Chen S, Wang J, Zou Y
International journal of molecular sciences 2022 Apr 28;23(9)
International journal of molecular sciences 2022 Apr 28;23(9)
Nicotinamide mononucleotide alleviates heat stress-induced oxidative stress and apoptosis in BMECs through reducing mitochondrial damage and endoplasmic reticulum stress.
Zeng HF, Xu J, Wang XL, Li SJ, Han ZY
Ecotoxicology and environmental safety 2022 Apr 15;235:113441
Ecotoxicology and environmental safety 2022 Apr 15;235:113441
Phosphorylation of Dynamin-Related Protein 1 (DRP1) Regulates Mitochondrial Dynamics and Skeletal Muscle Wasting in Cancer Cachexia.
Mao X, Gu Y, Sui X, Shen L, Han J, Wang H, Xi Q, Zhuang Q, Meng Q, Wu G
Frontiers in cell and developmental biology 2021;9:673618
Frontiers in cell and developmental biology 2021;9:673618
Mitochondrial Fusion Potentially Regulates a Metabolic Change in Tibetan Chicken Embryonic Brain During Hypoxia.
Tang Q, Ding C, Xu Q, Bai Y, Xu Q, Wang K, Fang M
Frontiers in cell and developmental biology 2021;9:585166
Frontiers in cell and developmental biology 2021;9:585166
Tanshinone IIA Combined With Cyclosporine A Alleviates Lung Apoptosis Induced by Renal Ischemia-Reperfusion in Obese Rats.
Tai H, Jiang XL, Song N, Xiao HH, Li Y, Cheng MJ, Yin XM, Chen YR, Yang GL, Jiang XY, Kuang JS, Lan ZM, Jia LQ
Frontiers in medicine 2021;8:617393
Frontiers in medicine 2021;8:617393
Oxyberberine Prevented Lipopolysaccharide-Induced Acute Lung Injury through Inhibition of Mitophagy.
Zhao R, Wang B, Wang D, Wu B, Ji P, Tan D
Oxidative medicine and cellular longevity 2021;2021:6675264
Oxidative medicine and cellular longevity 2021;2021:6675264
RNA-Seq Profiling to Investigate the Mechanism of Qishen Granules on Regulating Mitochondrial Energy Metabolism of Heart Failure in Rats.
He H, Li C, Lu X, Li Y, Li X, Sun X, Tang B, Wu Y, Li C
Evidence-based complementary and alternative medicine : eCAM 2021;2021:5779307
Evidence-based complementary and alternative medicine : eCAM 2021;2021:5779307
Dl-3-n-Butylphthalide Alleviates Behavioral and Cognitive Symptoms Via Modulating Mitochondrial Dynamics in the A53T-α-Synuclein Mouse Model of Parkinson's Disease.
Li H, Wang H, Zhang L, Wang M, Li Y
Frontiers in neuroscience 2021;15:647266
Frontiers in neuroscience 2021;15:647266
High-Fat Diet-Induced Mitochondrial Dysfunction Promotes Genioglossus Injury - A Potential Mechanism for Obstructive Sleep Apnea with Obesity.
Chen Q, Han X, Chen M, Zhao B, Sun B, Sun L, Zhang W, Yu L, Liu Y
Nature and science of sleep 2021;13:2203-2219
Nature and science of sleep 2021;13:2203-2219
Cordycepin Decreases Ischemia/Reperfusion Injury in Diabetic Hearts via Upregulating AMPK/Mfn2-dependent Mitochondrial Fusion.
Yu H, Hong X, Liu L, Wu Y, Xie X, Fang G, Zhi S
Frontiers in pharmacology 2021;12:754005
Frontiers in pharmacology 2021;12:754005
Mitofusin 2 Deficiency Causes Pro-Inflammatory Effects in Human Primary Macrophages.
Khodzhaeva V, Schreiber Y, Geisslinger G, Brandes RP, Brüne B, Namgaladze D
Frontiers in immunology 2021;12:723683
Frontiers in immunology 2021;12:723683
Tortoise Plastron and Deer Antler Gelatin Prevents Against Neuronal Mitochondrial Dysfunction In Vitro: Implication for a Potential Therapy of Alzheimer's Disease.
Cheng D, Yang XJ, Zhang L, Qin ZS, Li WQ, Xu HC, Zhang ZJ
Frontiers in pharmacology 2021;12:690256
Frontiers in pharmacology 2021;12:690256
Nicotine Causes Mitochondrial Dynamics Imbalance and Apoptosis Through ROS Mediated Mitophagy Impairment in Cardiomyocytes.
Meng TT, Wang W, Meng FL, Wang SY, Wu HH, Chen JM, Zheng Y, Wang GX, Zhang MX, Li Y, Su GH
Frontiers in physiology 2021;12:650055
Frontiers in physiology 2021;12:650055
Astragaloside II Ameliorated Podocyte Injury and Mitochondrial Dysfunction in Streptozotocin-Induced Diabetic Rats.
Su J, Gao C, Xie L, Fan Y, Shen Y, Huang Q, Wang N, Xu Y, Yang N, Gui D
Frontiers in pharmacology 2021;12:638422
Frontiers in pharmacology 2021;12:638422
Biochanin A Inhibits Glioblastoma Growth via Restricting Glycolysis and Mitochondrial Oxidative Phosphorylation.
Dong Q, Li Q, Duan L, Yin H, Wang X, Liu Y, Wang B, Li K, Yao X, Yuan G, Pan Y
Frontiers in oncology 2021;11:652008
Frontiers in oncology 2021;11:652008
The E3 ubiquitin ligase TRIM31 is involved in cerebral ischemic injury by promoting degradation of TIGAR.
Zeng S, Zhao Z, Zheng S, Wu M, Song X, Li Y, Zheng Y, Liu B, Chen L, Gao C, Liu H
Redox biology 2021 Sep;45:102058
Redox biology 2021 Sep;45:102058
MicroRNA-214 contributes to Ang II-induced cardiac hypertrophy by targeting SIRT3 to provoke mitochondrial malfunction.
Ding YQ, Zhang YH, Lu J, Li B, Yu WJ, Yue ZB, Hu YH, Wang PX, Li JY, Cai SD, Ye JT, Liu PQ
Acta pharmacologica Sinica 2021 Sep;42(9):1422-1436
Acta pharmacologica Sinica 2021 Sep;42(9):1422-1436
CISD3 inhibition drives cystine-deprivation induced ferroptosis.
Li Y, Wang X, Huang Z, Zhou Y, Xia J, Hu W, Wang X, Du J, Tong X, Wang Y
Cell death & disease 2021 Sep 8;12(9):839
Cell death & disease 2021 Sep 8;12(9):839
Effects of andrographolide on renal tubulointersticial injury and fibrosis. Evidence of its mechanism of action.
Liu W, Liang L, Zhang Q, Li Y, Yan S, Tang T, Ren Y, Mo J, Liu F, Chen X, Lan T
Phytomedicine : international journal of phytotherapy and phytopharmacology 2021 Oct;91:153650
Phytomedicine : international journal of phytotherapy and phytopharmacology 2021 Oct;91:153650
Inhibition of ER stress attenuates kidney injury and apoptosis induced by 3-MCPD via regulating mitochondrial fission/fusion and Ca(2+) homeostasis.
Zhong Y, Jin C, Han J, Zhu J, Liu Q, Sun D, Xia X, Peng X
Cell biology and toxicology 2021 Oct;37(5):795-809
Cell biology and toxicology 2021 Oct;37(5):795-809
SIRT3 protects bovine mammary epithelial cells from heat stress damage by activating the AMPK signaling pathway.
Sun XC, Wang Y, Zeng HF, Xi YM, Lin H, Han ZY, Chen KL
Cell death discovery 2021 Oct 21;7(1):304
Cell death discovery 2021 Oct 21;7(1):304
Trib1 deficiency causes brown adipose respiratory chain depletion and mitochondrial disorder.
Zhang X, Zhang B, Zhang C, Sun G, Sun X
Cell death & disease 2021 Nov 22;12(12):1098
Cell death & disease 2021 Nov 22;12(12):1098
Global ubiquitylation analysis of mitochondria in primary neurons identifies endogenous Parkin targets following activation of PINK1.
Antico O, Ordureau A, Stevens M, Singh F, Nirujogi RS, Gierlinski M, Barini E, Rickwood ML, Prescott A, Toth R, Ganley IG, Harper JW, Muqit MMK
Science advances 2021 Nov 12;7(46):eabj0722
Science advances 2021 Nov 12;7(46):eabj0722
Acetaldehyde Dehydrogenase 2 regulates HMG-CoA reductase stability and cholesterol synthesis in the liver.
Zhong S, Li L, Liang N, Zhang L, Xu X, Chen S, Yin H
Redox biology 2021 May;41:101919
Redox biology 2021 May;41:101919
Dihydromyricetin attenuates heat stress-induced apoptosis in dairy cow mammary epithelial cells through suppressing mitochondrial dysfunction.
Wang HL, Xing GD, Qian Y, Sun XF, Zhong JF, Chen KL
Ecotoxicology and environmental safety 2021 May;214:112078
Ecotoxicology and environmental safety 2021 May;214:112078
The AMPK-MFN2 axis regulates MAM dynamics and autophagy induced by energy stresses.
Hu Y, Chen H, Zhang L, Lin X, Li X, Zhuang H, Fan H, Meng T, He Z, Huang H, Gong Q, Zhu D, Xu Y, He P, Li L, Feng D
Autophagy 2021 May;17(5):1142-1156
Autophagy 2021 May;17(5):1142-1156
LACTB suppresses melanoma progression by attenuating PP1A and YAP interaction.
Ma Y, Wang L, He F, Yang J, Ding Y, Ge S, Fan X, Zhou Y, Xu X, Jia R
Cancer letters 2021 May 28;506:67-82
Cancer letters 2021 May 28;506:67-82
Mitocytosis, a migrasome-mediated mitochondrial quality-control process.
Jiao H, Jiang D, Hu X, Du W, Ji L, Yang Y, Li X, Sho T, Wang X, Li Y, Wu YT, Wei YH, Hu X, Yu L
Cell 2021 May 27;184(11):2896-2910.e13
Cell 2021 May 27;184(11):2896-2910.e13
Conditioned medium from induced pluripotent stem cell-derived mesenchymal stem cells accelerates cutaneous wound healing through enhanced angiogenesis.
Liang X, Lin F, Ding Y, Zhang Y, Li M, Zhou X, Meng Q, Ma X, Wei L, Fan H, Liu Z
Stem cell research & therapy 2021 May 20;12(1):295
Stem cell research & therapy 2021 May 20;12(1):295
High Dietary Fat Consumption Impairs Axonal Mitochondrial Function In Vivo.
Sajic M, Rumora AE, Kanhai AA, Dentoni G, Varatharajah S, Casey C, Brown RDR, Peters F, Hinder LM, Savelieff MG, Feldman EL, Smith KJ
The Journal of neuroscience : the official journal of the Society for Neuroscience 2021 May 12;41(19):4321-4334
The Journal of neuroscience : the official journal of the Society for Neuroscience 2021 May 12;41(19):4321-4334
Tanshinone IIA combined with CsA inhibit myocardial cell apoptosis induced by renal ischemia-reperfusion injury in obese rats.
Tai H, Jiang XL, Lan ZM, Li Y, Kong L, Yao SC, Song N, Lv MJ, Wu J, Yang P, Xiao XS, Yang GL, Kuang JS, Jia LQ
BMC complementary medicine and therapies 2021 Mar 22;21(1):100
BMC complementary medicine and therapies 2021 Mar 22;21(1):100
ALS/FTD mutations in UBQLN2 are linked to mitochondrial dysfunction through loss-of-function in mitochondrial protein import.
Lin BC, Phung TH, Higgins NR, Greenslade JE, Prado MA, Finley D, Karbowski M, Polster BM, Monteiro MJ
Human molecular genetics 2021 Jun 17;30(13):1230-1246
Human molecular genetics 2021 Jun 17;30(13):1230-1246
Sulforaphane Balances Ca(2+) Homeostasis Injured by Excessive Fat via Mitochondria-Associated Membrane (MAM).
Tian S, Lei P, Zhang J, Sun Y, Li B, Shan Y
Molecular nutrition & food research 2021 Jul;65(14):e2001076
Molecular nutrition & food research 2021 Jul;65(14):e2001076
DHA exhibits synergistic therapeutic efficacy with cisplatin to induce ferroptosis in pancreatic ductal adenocarcinoma via modulation of iron metabolism.
Du J, Wang X, Li Y, Ren X, Zhou Y, Hu W, Zhou C, Jing Q, Yang C, Wang L, Li H, Fang L, Zhou Y, Tong X, Wang Y
Cell death & disease 2021 Jul 15;12(7):705
Cell death & disease 2021 Jul 15;12(7):705
miR-34a-5p regulates PINK1-mediated mitophagy via multiple modes.
Tai Y, Pu M, Yuan L, Guo H, Qiao J, Lu H, Wang G, Chen J, Qi X, Tao Z, Ren J
Life sciences 2021 Jul 1;276:119415
Life sciences 2021 Jul 1;276:119415
Mesenchymal stem cells ameliorate lipid metabolism through reducing mitochondrial damage of hepatocytes in the treatment of post-hepatectomy liver failure.
Wang JL, Ding HR, Pan CY, Shi XL, Ren HZ
Cell death & disease 2021 Jan 21;12(1):111
Cell death & disease 2021 Jan 21;12(1):111
CHIP protects against MPP(+)/MPTP-induced damage by regulating Drp1 in two models of Parkinson's disease.
Hu Z, Mao C, Wang H, Zhang Z, Zhang S, Luo H, Tang M, Yang J, Yuan Y, Wang Y, Liu Y, Fan L, Zhang Q, Yao D, Liu F, Schisler JC, Shi C, Xu Y
Aging 2021 Jan 2;13(1):1458-1472
Aging 2021 Jan 2;13(1):1458-1472
DsbA-L deficiency in T cells promotes diet-induced thermogenesis through suppressing IFN-γ production.
Zhou H, Peng X, Hu J, Wang L, Luo H, Zhang J, Zhang Y, Li G, Ji Y, Zhang J, Bai J, Liu M, Zhou Z, Liu F
Nature communications 2021 Jan 12;12(1):326
Nature communications 2021 Jan 12;12(1):326
OPA1 haploinsufficiency due to a novel splicing variant resulting in mitochondrial dysfunction without mitochondrial DNA depletion.
Sun C, Wu X, Bai HX, Wang C, Liu Z, Yang C, Lu Y, Jiang P
Ophthalmic genetics 2021 Feb;42(1):45-52
Ophthalmic genetics 2021 Feb;42(1):45-52
Oxidative stress-induced mitophagy is suppressed by the miR-106b-93-25 cluster in a protective manner.
Zhang C, Nie P, Zhou C, Hu Y, Duan S, Gu M, Jiang D, Wang Y, Deng Z, Chen J, Chen S, Wang L
Cell death & disease 2021 Feb 24;12(2):209
Cell death & disease 2021 Feb 24;12(2):209
PINCH-1 promotes Δ(1)-pyrroline-5-carboxylate synthase expression and contributes to proline metabolic reprogramming in lung adenocarcinoma.
Cui C, Wang J, Guo L, Wu C
Amino acids 2021 Dec;53(12):1875-1890
Amino acids 2021 Dec;53(12):1875-1890
Caffeine promotes angiogenesis through modulating endothelial mitochondrial dynamics.
Wang LT, He PC, Li AQ, Cao KX, Yan JW, Guo S, Jiang L, Yao L, Dai XY, Feng D, Xu YM, Tan N
Acta pharmacologica Sinica 2021 Dec;42(12):2033-2045
Acta pharmacologica Sinica 2021 Dec;42(12):2033-2045
Possible relationship between mitochondrial changes and oxidative stress under low dose-rate irradiation.
Meng Q, Zaharieva EK, Sasatani M, Kobayashi J
Redox report : communications in free radical research 2021 Dec;26(1):160-169
Redox report : communications in free radical research 2021 Dec;26(1):160-169
LKB1/AMPKα signaling pathway and mitochondrial fission/fusion dynamics regulate apoptosis induced by 3-chlorpropane-1,2-diol in HEK293 cells.
Jin C, Xue W, Liu Q, Han J, Luo R, Feng J, Liu J, Guo T, Peng X, Hu T
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 2021 Aug;154:112350
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 2021 Aug;154:112350
Extract of Cynomorium songaricum ameliorates mitochondrial ultrastructure impairments and dysfunction in two different in vitro models of Alzheimer's disease.
Cheng D, Su L, Wang X, Li X, Li L, Hu M, Lu Y
BMC complementary medicine and therapies 2021 Aug 9;21(1):206
BMC complementary medicine and therapies 2021 Aug 9;21(1):206
Ginsenoside Rg5 Improves Insulin Resistance and Mitochondrial Biogenesis of Liver via Regulation of the Sirt1/PGC-1α Signaling Pathway in db/db Mice.
Zhu Y, Yang H, Deng J, Fan D
Journal of agricultural and food chemistry 2021 Aug 4;69(30):8428-8439
Journal of agricultural and food chemistry 2021 Aug 4;69(30):8428-8439
VPS13D interacts with VCP/p97 and negatively regulates endoplasmic reticulum-mitochondria interactions.
Du Y, Wang J, Xiong J, Fang N, Ji WK
Molecular biology of the cell 2021 Aug 1;32(16):1474-1486
Molecular biology of the cell 2021 Aug 1;32(16):1474-1486
Mst1 Knockout Alleviates Mitochondrial Fission and Mitigates Left Ventricular Remodeling in the Development of Diabetic Cardiomyopathy.
Feng X, Wang S, Yang X, Lin J, Man W, Dong Y, Zhang Y, Zhao Z, Wang H, Sun D
Frontiers in cell and developmental biology 2020;8:628842
Frontiers in cell and developmental biology 2020;8:628842
Deletion of Bmal1 Impairs Pancreatic β-Cell Function via Mitochondrial Signaling Pathway.
Ye L, Wu H, Xu W
BioMed research international 2020;2020:9803024
BioMed research international 2020;2020:9803024
Role of Nrf2 in Lipopolysaccharide-Induced Acute Kidney Injury: Protection by Human Umbilical Cord Blood Mononuclear Cells.
Feng LX, Zhao F, Liu Q, Peng JC, Duan XJ, Yan P, Wu X, Wang HS, Deng YH, Duan SB
Oxidative medicine and cellular longevity 2020;2020:6123459
Oxidative medicine and cellular longevity 2020;2020:6123459
Proteomic Profile of Mouse Brain Aging Contributions to Mitochondrial Dysfunction, DNA Oxidative Damage, Loss of Neurotrophic Factor, and Synaptic and Ribosomal Proteins.
Li Y, Yu H, Chen C, Li S, Zhang Z, Xu H, Zhu F, Liu J, Spencer PS, Dai Z, Yang X
Oxidative medicine and cellular longevity 2020;2020:5408452
Oxidative medicine and cellular longevity 2020;2020:5408452
A Long-Term Enriched Environment Ameliorates the Accelerated Age-Related Memory Impairment Induced by Gestational Administration of Lipopolysaccharide: Role of Plastic Mitochondrial Quality Control.
Zhuang ZQ, Zhang ZZ, Zhang YM, Ge HH, Sun SY, Zhang P, Chen GH
Frontiers in cellular neuroscience 2020;14:559182
Frontiers in cellular neuroscience 2020;14:559182
Bu-Yin-Qian-Zheng Formula Ameliorates MPP(+)-Induced Mitochondrial Dysfunction in Parkinson's Disease via Parkin.
Ma HJ, Gai C, Chai Y, Feng WD, Cheng CC, Zhang JK, Zhang YX, Yang LP, Guo ZY, Gao YS, Sun HM
Frontiers in pharmacology 2020;11:577017
Frontiers in pharmacology 2020;11:577017
Promotion of mitochondrial fusion protects against developmental PBDE-47 neurotoxicity by restoring mitochondrial homeostasis and suppressing excessive apoptosis.
Dong L, Li P, Yang K, Liu L, Gao H, Zhou G, Zhao Q, Xia T, Wang A, Zhang S
Theranostics 2020;10(3):1245-1261
Theranostics 2020;10(3):1245-1261
Ferroptosis mediated by the interaction between Mfn2 and IREα promotes arsenic-induced nonalcoholic steatohepatitis.
Wei S, Qiu T, Wang N, Yao X, Jiang L, Jia X, Tao Y, Zhang J, Zhu Y, Yang G, Liu X, Liu S, Sun X
Environmental research 2020 Sep;188:109824
Environmental research 2020 Sep;188:109824
The renoprotective effect of diosgenin on aristolochic acid I-induced renal injury in rats: impact on apoptosis, mitochondrial dynamics and autophagy.
Jin C, Miao X, Zhong Y, Han J, Liu Q, Zhu J, Xia X, Peng X
Food & function 2020 Sep 23;11(9):7456-7467
Food & function 2020 Sep 23;11(9):7456-7467
A substrate-trapping strategy to find E3 ubiquitin ligase substrates identifies Parkin and TRIM28 targets.
Watanabe M, Saeki Y, Takahashi H, Ohtake F, Yoshida Y, Kasuga Y, Kondo T, Yaguchi H, Suzuki M, Ishida H, Tanaka K, Hatakeyama S
Communications biology 2020 Oct 20;3(1):592
Communications biology 2020 Oct 20;3(1):592
Drp1-dependent mitochondrial fission contributes to Cr(VI)-induced mitophagy and hepatotoxicity.
Zhang Y, Ma Y, Xiao Y, Lu C, Xiao F
Ecotoxicology and environmental safety 2020 Oct 15;203:110928
Ecotoxicology and environmental safety 2020 Oct 15;203:110928
PINCH-1 regulates mitochondrial dynamics to promote proline synthesis and tumor growth.
Guo L, Cui C, Wang J, Yuan J, Yang Q, Zhang P, Su W, Bao R, Ran J, Wu C
Nature communications 2020 Oct 1;11(1):4913
Nature communications 2020 Oct 1;11(1):4913
HIF-1α ameliorates tubular injury in diabetic nephropathy via HO-1-mediated control of mitochondrial dynamics.
Jiang N, Zhao H, Han Y, Li L, Xiong S, Zeng L, Xiao Y, Wei L, Xiong X, Gao P, Yang M, Liu Y, Sun L
Cell proliferation 2020 Nov;53(11):e12909
Cell proliferation 2020 Nov;53(11):e12909
PDK4 promotes vascular calcification by interfering with autophagic activity and metabolic reprogramming.
Ma WQ, Sun XJ, Zhu Y, Liu NF
Cell death & disease 2020 Nov 17;11(11):991
Cell death & disease 2020 Nov 17;11(11):991
DIPK2A promotes STX17- and VAMP7-mediated autophagosome-lysosome fusion by binding to VAMP7B.
Tian X, Zheng P, Zhou C, Wang X, Ma H, Ma W, Zhou X, Teng J, Chen J
Autophagy 2020 May;16(5):797-810
Autophagy 2020 May;16(5):797-810
ChREBP-β regulates thermogenesis in brown adipose tissue.
Wei C, Ma X, Su K, Qi S, Zhu Y, Lin J, Wang C, Yang R, Chen X, Wang W, Zhang WJ
The Journal of endocrinology 2020 Jun;245(3):343-356
The Journal of endocrinology 2020 Jun;245(3):343-356
Oroxylin a promotes PGC-1α/Mfn2 signaling to attenuate hepatocyte pyroptosis via blocking mitochondrial ROS in alcoholic liver disease.
Kai J, Yang X, Wang Z, Wang F, Jia Y, Wang S, Tan S, Chen A, Shao J, Zhang F, Zhang Z, Zheng S
Free radical biology & medicine 2020 Jun;153:89-102
Free radical biology & medicine 2020 Jun;153:89-102
Melatonin regulates mitochondrial dynamics and alleviates neuron damage in prion diseases.
Zhang X, Zhao D, Wu W, Ali Shah SZ, Lai M, Yang D, Li J, Guan Z, Li W, Gao H, Zhao H, Zhou X, Yang L
Aging 2020 Jun 10;12(11):11139-11151
Aging 2020 Jun 10;12(11):11139-11151
Tetrahydroxy stilbene glycoside alleviated inflammatory damage by mitophagy via AMPK related PINK1/Parkin signaling pathway.
Gao Y, Li J, Li J, Hu C, Zhang L, Yan J, Li L, Zhang L
Biochemical pharmacology 2020 Jul;177:113997
Biochemical pharmacology 2020 Jul;177:113997
Chicken thalamic injury induced by copper (II) or / and arsenite exposure involves oxidative stress and inflammation-induced apoptosis.
Wang D, Zong C, Cheng K
Ecotoxicology and environmental safety 2020 Jul 1;197:110554
Ecotoxicology and environmental safety 2020 Jul 1;197:110554
Tongmai formula improves cardiac function via regulating mitochondrial quality control in the myocardium with ischemia/reperfusion injury.
Zhao Y, Guo R, Li L, Li S, Fan G, Zhao X, Wang Y
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2020 Dec;132:110897
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2020 Dec;132:110897
Sodium-glucose cotransporter 2 inhibition attenuates protein overload in renal proximal tubule via suppression of megalin O-GlcNacylation in progressive diabetic nephropathy.
Otomo H, Nara M, Kato S, Shimizu T, Suganuma Y, Sato T, Morii T, Yamada Y, Fujita H
Metabolism: clinical and experimental 2020 Dec;113:154405
Metabolism: clinical and experimental 2020 Dec;113:154405
Klf5 down-regulation induces vascular senescence through eIF5a depletion and mitochondrial fission.
Ma D, Zheng B, Liu HL, Zhao YB, Liu X, Zhang XH, Li Q, Shi WB, Suzuki T, Wen JK
PLoS biology 2020 Aug;18(8):e3000808
PLoS biology 2020 Aug;18(8):e3000808
TLR4 knockout upregulates the expression of Mfn2 and PGC-1α in a high-fat diet and ischemia-reperfusion mice model of liver injury.
Zhang C, Jia Y, Liu B, Wang G, Zhang Y
Life sciences 2020 Aug 1;254:117762
Life sciences 2020 Aug 1;254:117762
Heat stress induces apoptosis through disruption of dynamic mitochondrial networks in dairy cow mammary epithelial cells.
Chen KL, Wang HL, Jiang LZ, Qian Y, Yang CX, Chang WW, Zhong JF, Xing GD
In vitro cellular & developmental biology. Animal 2020 Apr;56(4):322-331
In vitro cellular & developmental biology. Animal 2020 Apr;56(4):322-331
Exogenous H(2)S Promoted USP8 Sulfhydration to Regulate Mitophagy in the Hearts of db/db Mice.
Sun Y, Lu F, Yu X, Wang B, Chen J, Lu F, Peng S, Sun X, Yu M, Chen H, Wang Y, Zhang L, Liu N, Du H, Zhao D, Zhang W
Aging and disease 2020 Apr;11(2):269-285
Aging and disease 2020 Apr;11(2):269-285
DsbA-L deficiency exacerbates mitochondrial dysfunction of tubular cells in diabetic kidney disease.
Gao P, Yang M, Chen X, Xiong S, Liu J, Sun L
Clinical science (London, England : 1979) 2020 Apr 17;134(7):677-694
Clinical science (London, England : 1979) 2020 Apr 17;134(7):677-694
Spermidine Prevents Heart Injury in Neonatal Rats Exposed to Intrauterine Hypoxia by Inhibiting Oxidative Stress and Mitochondrial Fragmentation.
Chai N, Zhang H, Li L, Yu X, Liu Y, Lin Y, Wang L, Yan J, Nikolaevna SE, Zhao Y
Oxidative medicine and cellular longevity 2019;2019:5406468
Oxidative medicine and cellular longevity 2019;2019:5406468
Impaired Mitochondrial Fusion and Oxidative Phosphorylation Triggered by High Glucose Is Mediated by Tom22 in Endothelial Cells.
Zeng Y, Pan Q, Wang X, Li D, Lin Y, Man F, Xiao F, Guo L
Oxidative medicine and cellular longevity 2019;2019:4508762
Oxidative medicine and cellular longevity 2019;2019:4508762
The Neuroprotective Effect of Hemin and the Related Mechanism in Sevoflurane Exposed Neonatal Rats.
Yang F, Shan Y, Tang Z, Wu X, Bi C, Zhang Y, Gao Y, Liu H
Frontiers in neuroscience 2019;13:537
Frontiers in neuroscience 2019;13:537
Da-Bu-Yin-Wan and Qian-Zheng-San Ameliorate Mitochondrial Dynamics in the Parkinson's Disease Cell Model Induced by MPP().
Gai C, Feng WD, Qiang TY, Ma HJ, Chai Y, Zhang SJ, Guo ZY, Hu JH, Sun HM
Frontiers in pharmacology 2019;10:372
Frontiers in pharmacology 2019;10:372
Mitochondrial dysfunction in endothelial cells induced by airborne fine particulate matter (<2.5 μm).
Miao X, Li W, Niu B, Li J, Sun J, Qin M, Zhou Z
Journal of applied toxicology : JAT 2019 Oct;39(10):1424-1432
Journal of applied toxicology : JAT 2019 Oct;39(10):1424-1432
DsbA-L ameliorates high glucose induced tubular damage through maintaining MAM integrity.
Yang M, Zhao L, Gao P, Zhu X, Han Y, Chen X, Li L, Xiao Y, Wei L, Li C, Xiao L, Yuan S, Liu F, Dong LQ, Kanwar YS, Sun L
EBioMedicine 2019 May;43:607-619
EBioMedicine 2019 May;43:607-619
Roles of mitochondrial fission inhibition in developmental fluoride neurotoxicity: mechanisms of action in vitro and associations with cognition in rats and children.
Zhao Q, Niu Q, Chen J, Xia T, Zhou G, Li P, Dong L, Xu C, Tian Z, Luo C, Liu L, Zhang S, Wang A
Archives of toxicology 2019 Mar;93(3):709-726
Archives of toxicology 2019 Mar;93(3):709-726
Reduced mitochondrial fusion and Huntingtin levels contribute to impaired dendritic maturation and behavioral deficits in Fmr1-mutant mice.
Shen M, Wang F, Li M, Sah N, Stockton ME, Tidei JJ, Gao Y, Korabelnikov T, Kannan S, Vevea JD, Chapman ER, Bhattacharyya A, van Praag H, Zhao X
Nature neuroscience 2019 Mar;22(3):386-400
Nature neuroscience 2019 Mar;22(3):386-400
CDDO-Me Selectively Attenuates CA1 Neuronal Death Induced by Status Epilepticus via Facilitating Mitochondrial Fission Independent of LONP1.
Kim JE, Park H, Choi SH, Kong MJ, Kang TC
Cells 2019 Aug 5;8(8)
Cells 2019 Aug 5;8(8)
Mitochondrial Dynamics Is Critical for the Full Pluripotency and Embryonic Developmental Potential of Pluripotent Stem Cells.
Zhong X, Cui P, Cai Y, Wang L, He X, Long P, Lu K, Yan R, Zhang Y, Pan X, Zhao X, Li W, Zhang H, Zhou Q, Gao P
Cell metabolism 2019 Apr 2;29(4):979-992.e4
Cell metabolism 2019 Apr 2;29(4):979-992.e4
The human Obg protein GTPBP10 is involved in mitoribosomal biogenesis.
Lavdovskaia E, Kolander E, Steube E, Mai MM, Urlaub H, Richter-Dennerlein R
Nucleic acids research 2018 Sep 19;46(16):8471-8482
Nucleic acids research 2018 Sep 19;46(16):8471-8482
In Vivo Deletion of β-Cell Drp1 Impairs Insulin Secretion Without Affecting Islet Oxygen Consumption.
Hennings TG, Chopra DG, DeLeon ER, VanDeusen HR, Sesaki H, Merrins MJ, Ku GM
Endocrinology 2018 Sep 1;159(9):3245-3256
Endocrinology 2018 Sep 1;159(9):3245-3256
Phosphorylation of Parkin at serine 131 by p38 MAPK promotes mitochondrial dysfunction and neuronal death in mutant A53T α-synuclein model of Parkinson's disease.
Chen J, Ren Y, Gui C, Zhao M, Wu X, Mao K, Li W, Zou F
Cell death & disease 2018 Jun 13;9(6):700
Cell death & disease 2018 Jun 13;9(6):700
Mutant APP and amyloid beta-induced defective autophagy, mitophagy, mitochondrial structural and functional changes and synaptic damage in hippocampal neurons from Alzheimer's disease.
Reddy PH, Yin X, Manczak M, Kumar S, Pradeepkiran JA, Vijayan M, Reddy AP
Human molecular genetics 2018 Jul 15;27(14):2502-2516
Human molecular genetics 2018 Jul 15;27(14):2502-2516
GLUT10 maintains the integrity of major arteries through regulation of redox homeostasis and mitochondrial function.
Syu YW, Lai HW, Jiang CL, Tsai HY, Lin CC, Lee YC
Human molecular genetics 2018 Jan 15;27(2):307-321
Human molecular genetics 2018 Jan 15;27(2):307-321
Hypertonia-linked protein Trak1 functions with mitofusins to promote mitochondrial tethering and fusion.
Lee CA, Chin LS, Li L
Protein & cell 2018 Aug;9(8):693-716
Protein & cell 2018 Aug;9(8):693-716
DNA damage triggers tubular endoplasmic reticulum extension to promote apoptosis by facilitating ER-mitochondria signaling.
Zheng P, Chen Q, Tian X, Qian N, Chai P, Liu B, Hu J, Blackstone C, Zhu D, Teng J, Chen J
Cell research 2018 Aug;28(8):833-854
Cell research 2018 Aug;28(8):833-854
Neuroprotective Effect and Mechanism of Thiazolidinedione on Dopaminergic Neurons In Vivo and In Vitro in Parkinson's Disease.
Wang Y, Zhao W, Li G, Chen J, Guan X, Chen X, Guan Z
PPAR research 2017;2017:4089214
PPAR research 2017;2017:4089214
Succinate promotes stem cell migration through the GPR91-dependent regulation of DRP1-mediated mitochondrial fission.
Ko SH, Choi GE, Oh JY, Lee HJ, Kim JS, Chae CW, Choi D, Han HJ
Scientific reports 2017 Oct 3;7(1):12582
Scientific reports 2017 Oct 3;7(1):12582
Lysosomal Proteolysis Is Associated With Exercise-Induced Improvement of Mitochondrial Quality Control in Aged Hippocampus.
Luo L, Dai JR, Guo SS, Lu AM, Gao XF, Gu YR, Zhang XF, Xu HD, Wang Y, Zhu Z, Wood LJ, Qin ZH
The journals of gerontology. Series A, Biological sciences and medical sciences 2017 Oct 1;72(10):1342-1351
The journals of gerontology. Series A, Biological sciences and medical sciences 2017 Oct 1;72(10):1342-1351
Impaired mitochondrial fusion, autophagy, biogenesis and dysregulated lipid metabolism is associated with preeclampsia.
Zhou X, Han TL, Chen H, Baker PN, Qi H, Zhang H
Experimental cell research 2017 Oct 1;359(1):195-204
Experimental cell research 2017 Oct 1;359(1):195-204
Fatty acid synthesis is critical for stem cell pluripotency via promoting mitochondrial fission.
Wang L, Zhang T, Wang L, Cai Y, Zhong X, He X, Hu L, Tian S, Wu M, Hui L, Zhang H, Gao P
The EMBO journal 2017 May 15;36(10):1330-1347
The EMBO journal 2017 May 15;36(10):1330-1347
Maternal exercise upregulates mitochondrial gene expression and increases enzyme activity of fetal mouse hearts.
Chung E, Joiner HE, Skelton T, Looten KD, Manczak M, Reddy PH
Physiological reports 2017 Mar;5(5)
Physiological reports 2017 Mar;5(5)
Salvianolic acid B inhibits mitochondrial dysfunction by up-regulating mortalin.
Liu Y, Hu Y, E Q, Zuo J, Yang L, Liu W
Scientific reports 2017 Mar 2;7:43097
Scientific reports 2017 Mar 2;7:43097
TRPC6-mediated ERK1/2 phosphorylation prevents dentate granule cell degeneration via inhibiting mitochondrial elongation.
Ko AR, Kang TC
Neuropharmacology 2017 Jul 15;121:120-129
Neuropharmacology 2017 Jul 15;121:120-129
An mtDNA mutation accelerates liver aging by interfering with the ROS response and mitochondrial life cycle.
Niemann J, Johne C, Schröder S, Koch F, Ibrahim SM, Schultz J, Tiedge M, Baltrusch S
Free radical biology & medicine 2017 Jan;102:174-187
Free radical biology & medicine 2017 Jan;102:174-187
Hydrogen Sulphide modulating mitochondrial morphology to promote mitophagy in endothelial cells under high-glucose and high-palmitate.
Liu N, Wu J, Zhang L, Gao Z, Sun Y, Yu M, Zhao Y, Dong S, Lu F, Zhang W
Journal of cellular and molecular medicine 2017 Dec;21(12):3190-3203
Journal of cellular and molecular medicine 2017 Dec;21(12):3190-3203
The inflammatory responses in Cu-mediated elemental imbalance is associated with mitochondrial fission and intrinsic apoptosis in Gallus gallus heart.
Li S, Zhao H, Wang Y, Shao Y, Li J, Liu J, Xing M
Chemosphere 2017 Dec;189:489-497
Chemosphere 2017 Dec;189:489-497
Antagonistic effects of selenium on cadmium-induced apoptosis by restoring the mitochondrial dynamic equilibrium and energy metabolism in chicken spleens.
Xu Z, Jin X, Pan T, Liu T, Wan N, Li S
Oncotarget 2017 Aug 8;8(32):52629-52641
Oncotarget 2017 Aug 8;8(32):52629-52641
MiR-106b-mediated Mfn2 suppression is critical for PKM2 induced mitochondrial fusion.
Wu H, Li Z, Wang Y, Yang P, Li Z, Li H, Wu C
American journal of cancer research 2016;6(10):2221-2234
American journal of cancer research 2016;6(10):2221-2234
Exogenous H2S modulates mitochondrial fusion-fission to inhibit vascular smooth muscle cell proliferation in a hyperglycemic state.
Sun A, Wang Y, Liu J, Yu X, Sun Y, Yang F, Dong S, Wu J, Zhao Y, Xu C, Lu F, Zhang W
Cell & bioscience 2016;6:36
Cell & bioscience 2016;6:36
Dysfunctional tubular endoplasmic reticulum constitutes a pathological feature of Alzheimer's disease.
Sharoar MG, Shi Q, Ge Y, He W, Hu X, Perry G, Zhu X, Yan R
Molecular psychiatry 2016 Sep;21(9):1263-71
Molecular psychiatry 2016 Sep;21(9):1263-71
SAMM50 Affects Mitochondrial Morphology through the Association of Drp1 in Mammalian Cells.
Liu S, Gao Y, Zhang C, Li H, Pan S, Wang X, Du S, Deng Z, Wang L, Song Z, Chen S
FEBS letters 2016 May;590(9):1313-23
FEBS letters 2016 May;590(9):1313-23
Mic60/Mitofilin determines MICOS assembly essential for mitochondrial dynamics and mtDNA nucleoid organization.
Li H, Ruan Y, Zhang K, Jian F, Hu C, Miao L, Gong L, Sun L, Zhang X, Chen S, Chen H, Liu D, Song Z
Cell death and differentiation 2016 Mar;23(3):380-92
Cell death and differentiation 2016 Mar;23(3):380-92
Lost region in amyloid precursor protein (APP) through TALEN-mediated genome editing alters mitochondrial morphology.
Wang Y, Wu F, Pan H, Zheng W, Feng C, Wang Y, Deng Z, Wang L, Luo J, Chen S
Scientific reports 2016 Feb 29;6:22244
Scientific reports 2016 Feb 29;6:22244
ABT737 reverses cisplatin resistance by regulating ER-mitochondria Ca2+ signal transduction in human ovarian cancer cells.
Xie Q, Su J, Jiao B, Shen L, Ma L, Qu X, Yu C, Jiang X, Xu Y, Sun L
International journal of oncology 2016 Dec;49(6):2507-2519
International journal of oncology 2016 Dec;49(6):2507-2519
Protective effects of reduced dynamin-related protein 1 against amyloid beta-induced mitochondrial dysfunction and synaptic damage in Alzheimer's disease.
Manczak M, Kandimalla R, Fry D, Sesaki H, Reddy PH
Human molecular genetics 2016 Dec 1;25(23):5148-5166
Human molecular genetics 2016 Dec 1;25(23):5148-5166
FUS Interacts with HSP60 to Promote Mitochondrial Damage.
Deng J, Yang M, Chen Y, Chen X, Liu J, Sun S, Cheng H, Li Y, Bigio EH, Mesulam M, Xu Q, Du S, Fushimi K, Zhu L, Wu JY
PLoS genetics 2015 Sep;11(9):e1005357
PLoS genetics 2015 Sep;11(9):e1005357
Relocation of p25α/tubulin polymerization promoting protein from the nucleus to the perinuclear cytoplasm in the oligodendroglia of sporadic and COQ2 mutant multiple system atrophy.
Ota K, Obayashi M, Ozaki K, Ichinose S, Kakita A, Tada M, Takahashi H, Ando N, Eishi Y, Mizusawa H, Ishikawa K
Acta neuropathologica communications 2014 Sep 11;2:136
Acta neuropathologica communications 2014 Sep 11;2:136
Inhibition of mitochondrial fission prevents cell cycle progression in lung cancer.
Rehman J, Zhang HJ, Toth PT, Zhang Y, Marsboom G, Hong Z, Salgia R, Husain AN, Wietholt C, Archer SL
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2012 May;26(5):2175-86
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2012 May;26(5):2175-86
Mitochondrial remodeling following fission inhibition by 15d-PGJ2 involves molecular changes in mitochondrial fusion protein OPA1.
Kar R, Mishra N, Singha PK, Venkatachalam MA, Saikumar P
Biochemical and biophysical research communications 2010 Sep 3;399(4):548-54
Biochemical and biophysical research communications 2010 Sep 3;399(4):548-54
No comments: Submit comment
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- mouse testis tissue were subjected to SDS PAGE followed by western blot with 12186-1-AP(MFN2 antibody) at dilution of 1:400
- Sample type
- tissue
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- IP Result of anti-MFN2 (IP:12186-1-AP, 3ug; Detection:12186-1-AP 1:1000) with mouse kidney tissue lysate 8000ug.
- Sample type
- tissue
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- The MFN2 antibody from Proteintech is a rabbit polyclonal antibody to a recombinant protein of human MFN2. This antibody recognizes human,mouse,rat antigen. The MFN2 antibody has been validated for the following applications: ELISA, WB, IHC, IP analysis.
