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Western blot
ImmunocytochemistryAntibody data
- Antibody Data
- Antigen structure
- References [6]
- Comments [0]
- Validations
- Western blot [1]
- ELISA [1]
- Immunohistochemistry [1]
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- Product number
- H00009927-M01 - Provider product page
- Provider
- Novus Biologicals
- Proper citation
- Novus Cat#H00009927-M01, RRID:AB_791141
- Product name
- Mouse Monoclonal Mitofusin 2 Antibody
- Antibody type
- Monoclonal
- Description
- IgG purified. MFN2 (6A8)
- Reactivity
- Human, Mouse, Rat
- Host
- Mouse
- Isotype
- IgG
- Vial size
- 0.1 mg
- Storage
- Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.
Submitted references ATAD3A oligomerization causes neurodegeneration by coupling mitochondrial fragmentation and bioenergetics defects.
A selective inhibitor of mitofusin 1-βIIPKC association improves heart failure outcome in rats.
Effect of Roux-en-Y gastric bypass on liver mitochondrial dynamics in a rat model of obesity.
A new mitofusin topology places the redox-regulated C terminus in the mitochondrial intermembrane space.
Increase in proteins involved in mitochondrial fission, mitophagy, proteolysis and antioxidant response in type I endometrial cancer as an adaptive response to respiratory complex I deficiency.
Mitochondrial and metabolic dysfunction in renal convoluted tubules of obese mice: protective role of melatonin.
Zhao Y, Sun X, Hu D, Prosdocimo DA, Hoppel C, Jain MK, Ramachandran R, Qi X
Nature communications 2019 Mar 26;10(1):1371
Nature communications 2019 Mar 26;10(1):1371
A selective inhibitor of mitofusin 1-βIIPKC association improves heart failure outcome in rats.
Ferreira JCB, Campos JC, Qvit N, Qi X, Bozi LHM, Bechara LRG, Lima VM, Queliconi BB, Disatnik MH, Dourado PMM, Kowaltowski AJ, Mochly-Rosen D
Nature communications 2019 Jan 18;10(1):329
Nature communications 2019 Jan 18;10(1):329
Effect of Roux-en-Y gastric bypass on liver mitochondrial dynamics in a rat model of obesity.
Sacks J, Mulya A, Fealy CE, Huang H, Mosinski JD, Pagadala MR, Shimizu H, Batayyah E, Schauer PR, Brethauer SA, Kirwan JP
Physiological reports 2018 Feb;6(4)
Physiological reports 2018 Feb;6(4)
A new mitofusin topology places the redox-regulated C terminus in the mitochondrial intermembrane space.
Mattie S, Riemer J, Wideman JG, McBride HM
The Journal of cell biology 2018 Feb 5;217(2):507-515
The Journal of cell biology 2018 Feb 5;217(2):507-515
Increase in proteins involved in mitochondrial fission, mitophagy, proteolysis and antioxidant response in type I endometrial cancer as an adaptive response to respiratory complex I deficiency.
Cormio A, Musicco C, Gasparre G, Cormio G, Pesce V, Sardanelli AM, Gadaleta MN
Biochemical and biophysical research communications 2017 Sep 9;491(1):85-90
Biochemical and biophysical research communications 2017 Sep 9;491(1):85-90
Mitochondrial and metabolic dysfunction in renal convoluted tubules of obese mice: protective role of melatonin.
Stacchiotti A, Favero G, Giugno L, Lavazza A, Reiter RJ, Rodella LF, Rezzani R
PloS one 2014;9(10):e111141
PloS one 2014;9(10):e111141
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Supportive validation
- Submitted by
- Novus Biologicals (provider)
- Main image
- Experimental details
- Western Blot: Mitofusin 2 Antibody (6A8) [H00009927-M01] - MFN2 monoclonal antibody (M01), clone 6A8. Analysis of MFN2 expression in HeLa.
Supportive validation
- Submitted by
- Novus Biologicals (provider)
- Main image
- Experimental details
- ELISA: Mitofusin 2 Antibody (6A8) [H00009927-M01] - Detection limit for recombinant GST tagged MFN2 is 0.3 ng/ml as a capture antibody.
Supportive validation
- Submitted by
- Novus Biologicals (provider)
- Main image
- Experimental details
- Immunohistochemistry-Paraffin: Mitofusin 2 Antibody (6A8) [H00009927-M01] - Analysis of monoclonal antibody to MFN2 on formalin-fixed paraffin-embedded human kidney. Antibody concentration 3 ug/ml.
