HPA004117

antibody from Atlas Antibodies

Targeting: SUSD2 BK65A6.2, FLJ22778, W5C5

Immunohistochemistry (Supportive data in Antibodypedia)

Antibody Data

Product number

HPA004117

Provider

Atlas Antibodies

Proper citation

Atlas Antibodies Cat#HPA004117, RRID:AB_1857674

Product name

Anti-SUSD2

Antibody type

Polyclonal

Description

Polyclonal Antibody against Human SUSD2, Gene description: sushi domain containing 2, Alternative Gene Names: BK65A6.2, FLJ22778, Validated applications: IHC, Uniprot ID: Q9UGT4, Storage: Store at +4°C for short term storage. Long time storage is recommended at -20°C.

Reactivity

Human

Host

Rabbit

Conjugate

Unconjugated

Isotype

IgG

Vial size

100 µl

Concentration

0.3 mg/ml

Storage

Store at +4°C for short term storage. Long time storage is recommended at -20°C.

Handling

The antibody solution should be gently mixed before use.

References

Submitted references

Sushi Domain Containing 2 Dysfunction Contributes to Cancer Progression in Patients with Bladder Cancer

Kuo W, Lee Y, Yang Y, Cheng C, Tseng C, Tsai K
Journal of Cancer 2024;15(16):5318-5328

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SUSD2 suppresses CD8+ T cell antitumor immunity by targeting IL-2 receptor signaling

Zhao B, Gong W, Ma A, Chen J, Velegraki M, Dong H, Liu Z, Wang L, Okimoto T, Jones D, Lei Y, Long M, Oestreich K, Ma Q, Xin G, Carbone D, He K, Li Z, Wen H
Nature Immunology 2022;23(11):1588-1599

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Therapy-Induced Evolution of Human Lung Cancer Revealed by Single-Cell RNA Sequencing

Maynard A, McCoach C, Rotow J, Harris L, Haderk F, Kerr D, Yu E, Schenk E, Tan W, Zee A, Tan M, Gui P, Lea T, Wu W, Urisman A, Jones K, Sit R, Kolli P, Seeley E, Gesthalter Y, Le D, Yamauchi K, Naeger D, Bandyopadhyay S, Shah K, Cech L, Thomas N, Gupta A, Gonzalez M, Do H, Tan L, Bacaltos B, Gomez-Sjoberg R, Gubens M, Jahan T, Kratz J, Jablons D, Neff N, Doebele R, Weissman J, Blakely C, Darmanis S, Bivona T
Cell 2020;182(5):1232-1251.e22

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Loss of SUSD2 expression correlates with poor prognosis in patients with surgically resected lung adenocarcinoma

Guo W, Shao F, Sun S, Song P, Guo L, Xue X, Zhang G, Zhang H, Gao Y, Qiu B, Tan F, Gao S, He J
Journal of Cancer 2020;11(7):1648-1656

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SUSD2 expression correlates with decreased metastasis and increased survival in a high-grade serous ovarian cancer xenograft murine model

Sheets J, Patrick M, Egland K
Oncotarget 2020;11(24):2290-2301

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Epigenetic Targeting of Adipocytes Inhibits High-Grade Serous Ovarian Cancer Cell Migration and Invasion

Tang J, Pulliam N, Özeş A, Buechlein A, Ding N, Keer H, Rusch D, O'Hagan H, Stack M, Nephew K
Molecular Cancer Research 2018;16(8):1226-1240

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SUSD2 expression in high-grade serous ovarian cancer correlates with increased patient survival and defective mesothelial clearance

Sheets J, Iwanicki M, Liu J, Howitt B, Hirsch M, Gubbels J, Drapkin R, Egland K
Oncogenesis 2016;5(10):e264-e264

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CSBF/C10orf99, a novel potential cytokine, inhibits colon cancer cell growth through inducing G1 arrest

Pan W, Cheng Y, Zhang H, Liu B, Mo X, Li T, Li L, Cheng X, Zhang L, Ji J, Wang P, Han W
Scientific Reports 2014;4(1)

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Isolation and Characterization of Progenitor-Like Cells from Human Renal Proximal Tubules

Lindgren D, Boström A, Nilsson K, Hansson J, Sjölund J, Möller C, Jirström K, Nilsson E, Landberg G, Axelson H, Johansson M
The American Journal of Pathology 2011;178(2):828-837

Immunohistochemistry

Supportive validation

Submitted by

Atlas Antibodies (provider)

Enhanced method

Orthogonal validation

Main image

Experimental details

Immunohistochemistry analysis in human lung and liver tissues using HPA004117 antibody. Corresponding SUSD2 RNA-seq data are presented for the same tissues.

Sample type

Human

Protocol

Protocol

Orthogonal method

Orthogonal validation of protein expression using IHC by comparison to RNA-seq data of corresponding target in high and low expression tissues.

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