Antibody data
- Antibody Data
- Antigen structure
- References [13]
- Comments [0]
- Validations
- Western blot [1]
- Immunoprecipitation [1]
- Immunohistochemistry [1]
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Validation data
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- Product number
- 11561-1-AP - Provider product page
- Provider
- Proteintech Group
- Product name
- DGAT1 antibody
- Antibody type
- Polyclonal
- Description
- DGAT1 antibody (Cat. #11561-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse, rat and has been validated for the following applications: IHC, IP, WB, ELISA.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references Alteration of gastric microbiota and transcriptome in a rat with gastric intestinal metaplasia induced by deoxycholic acid.
Eight Zhes Decoction ameliorates the lipid dysfunction of nonalcoholic fatty liver disease using integrated lipidomics, network pharmacology and pharmacokinetics.
Inhibition of the SREBP pathway prevents SARS-CoV-2 replication and inflammasome activation.
Si-Ni-San reverses dietary fat absorption defects in a murine model of depression.
Exogenous H(2) S promotes ubiquitin-mediated degradation of SREBP1 to alleviate diabetic cardiomyopathy via SYVN1 S-sulfhydration.
A HIF-1α inhibitor combined with palmitic acid and L-carnitine treatment can prevent the fat metabolic reprogramming under hypoxia and induce apoptosis in hepatocellular carcinoma cells.
Graphene oxide links alterations of anti-viral signaling pathways with lipid metabolism via suppressing TLR3 in vascular smooth muscle cells.
Lipid Droplets Are Beneficial for Rabies Virus Replication by Facilitating Viral Budding.
Selective Inhibition of 11β-Hydroxysteroid Dehydrogenase Type 1 Attenuates High-Fat Diet-Induced Hepatic Steatosis in Mice.
Identification of an Aging-Related Gene Signature in Predicting Prognosis and Indicating Tumor Immune Microenvironment in Breast Cancer.
Deficiency of intestinal Bmal1 prevents obesity induced by high-fat feeding.
Hydrogen sulphide reduced the accumulation of lipid droplets in cardiac tissues of db/db mice via Hrd1 S-sulfhydration.
Cholestasis impairs hepatic lipid storage via AMPK and CREB signaling in hepatitis B virus surface protein transgenic mice.
Xu Z, Xiao L, Wang S, Cheng Y, Wu J, Meng Y, Bao K, Zhang J, Cheng C
Frontiers in microbiology 2023;14:1160821
Frontiers in microbiology 2023;14:1160821
Eight Zhes Decoction ameliorates the lipid dysfunction of nonalcoholic fatty liver disease using integrated lipidomics, network pharmacology and pharmacokinetics.
Zhou Y, Dai Z, Deng K, Wang Y, Ying J, Chu D, Zhou J, Tang C
Journal of pharmaceutical analysis 2023 Sep;13(9):1058-1069
Journal of pharmaceutical analysis 2023 Sep;13(9):1058-1069
Inhibition of the SREBP pathway prevents SARS-CoV-2 replication and inflammasome activation.
Soares VC, Dias SSG, Santos JC, Azevedo-Quintanilha IG, Moreira IBG, Sacramento CQ, Fintelman-Rodrigues N, Temerozo JR, da Silva MAN, Barreto-Vieira DF, Souza TM, Bozza PT
Life science alliance 2023 Nov;6(11)
Life science alliance 2023 Nov;6(11)
Si-Ni-San reverses dietary fat absorption defects in a murine model of depression.
Liu Y, Lv B, Tang K, Qu H, Yu F, Shi Y
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2023 Dec;168:115677
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2023 Dec;168:115677
Exogenous H(2) S promotes ubiquitin-mediated degradation of SREBP1 to alleviate diabetic cardiomyopathy via SYVN1 S-sulfhydration.
Zhang S, Wang M, Li H, Li Q, Liu N, Dong S, Zhao Y, Pang K, Huang J, Ren C, Wang Y, Tian Z, Lu F, Zhang W
Journal of cachexia, sarcopenia and muscle 2023 Dec;14(6):2719-2732
Journal of cachexia, sarcopenia and muscle 2023 Dec;14(6):2719-2732
A HIF-1α inhibitor combined with palmitic acid and L-carnitine treatment can prevent the fat metabolic reprogramming under hypoxia and induce apoptosis in hepatocellular carcinoma cells.
Matsufuji S, Kitajima Y, Higure K, Kimura N, Maeda S, Yamada K, Ito K, Tanaka T, Kai K, Noshiro H
Cancer & metabolism 2023 Dec 8;11(1):25
Cancer & metabolism 2023 Dec 8;11(1):25
Graphene oxide links alterations of anti-viral signaling pathways with lipid metabolism via suppressing TLR3 in vascular smooth muscle cells.
Luo Y, Li J, Huang C, Wang X, Long D, Cao Y
Molecular omics 2022 Sep 26;18(8):779-790
Molecular omics 2022 Sep 26;18(8):779-790
Lipid Droplets Are Beneficial for Rabies Virus Replication by Facilitating Viral Budding.
Zhao J, Zeng Z, Chen Y, Liu W, Chen H, Fu ZF, Zhao L, Zhou M
Journal of virology 2022 Jan 26;96(2):e0147321
Journal of virology 2022 Jan 26;96(2):e0147321
Selective Inhibition of 11β-Hydroxysteroid Dehydrogenase Type 1 Attenuates High-Fat Diet-Induced Hepatic Steatosis in Mice.
Li H, Sheng J, Wang J, Gao H, Yu J, Ding G, Ding N, He W, Zha J
Drug design, development and therapy 2021;15:2309-2324
Drug design, development and therapy 2021;15:2309-2324
Identification of an Aging-Related Gene Signature in Predicting Prognosis and Indicating Tumor Immune Microenvironment in Breast Cancer.
Lv W, Zhao C, Tan Y, Hu W, Yu H, Zeng N, Zhang Q, Wu Y
Frontiers in oncology 2021;11:796555
Frontiers in oncology 2021;11:796555
Deficiency of intestinal Bmal1 prevents obesity induced by high-fat feeding.
Yu F, Wang Z, Zhang T, Chen X, Xu H, Wang F, Guo L, Chen M, Liu K, Wu B
Nature communications 2021 Sep 7;12(1):5323
Nature communications 2021 Sep 7;12(1):5323
Hydrogen sulphide reduced the accumulation of lipid droplets in cardiac tissues of db/db mice via Hrd1 S-sulfhydration.
Sun Y, Zhang L, Lu B, Wen J, Wang M, Zhang S, Li Q, Shu F, Lu F, Liu N, Peng S, Zhao Y, Dong S, Lu F, Zhang W, Wang Y
Journal of cellular and molecular medicine 2021 Oct;25(19):9154-9167
Journal of cellular and molecular medicine 2021 Oct;25(19):9154-9167
Cholestasis impairs hepatic lipid storage via AMPK and CREB signaling in hepatitis B virus surface protein transgenic mice.
Irungbam K, Roderfeld M, Glimm H, Hempel F, Schneider F, Hehr L, Glebe D, Churin Y, Morlock G, Yüce I, Roeb E
Laboratory investigation; a journal of technical methods and pathology 2020 Nov;100(11):1411-1424
Laboratory investigation; a journal of technical methods and pathology 2020 Nov;100(11):1411-1424
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Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- mouse heart tissue were subjected to SDS PAGE followed by western blot with 11561-1-AP( DGAT1 Antibody) at dilution of 1:1000
- Sample type
- tissue
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- IP Result of anti-DGAT1 (IP:11561-1-AP, 3ug; Detection:11561-1-AP 1:300) with mouse heart tissue lysate 4000ug.
- Sample type
- tissue
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- The DGAT1 antibody from Proteintech is a rabbit polyclonal antibody to a recombinant protein of human DGAT1. This antibody recognizes human,mouse,rat antigen. The DGAT1 antibody has been validated for the following applications: ELISA, WB, IHC, IP analysis.