Antibody data
- Antibody Data
- Antigen structure
- References [11]
- Comments [0]
- Validations
- Western blot [2]
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Validation data
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- Product number
- NB110-41487 - Provider product page
- Provider
- Novus Biologicals
- Proper citation
- Novus Cat#NB110-41487, RRID:AB_805567
- Product name
- Rabbit Polyclonal DGAT1 Antibody
- Antibody type
- Polyclonal
- Description
- Immunogen affinity purified.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Isotype
- IgG
- Vial size
- 0.1 ml
- Concentration
- 1.0 mg/ml
- Storage
- Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.
Submitted references Experimental Activation of Endocannabinoid System Reveals Antilipotoxic Effects on Cardiac Myocytes.
Simvastatin-Induced Insulin Resistance May Be Linked to Decreased Lipid Uptake and Lipid Synthesis in Human Skeletal Muscle: the LIFESTAT Study.
Fatty acid transport protein 1 regulates retinoid metabolism and photoreceptor development in mouse retina.
Factors regulating subcutaneous adipose tissue storage, fibrosis, and inflammation may underlie low fatty acid mobilization in insulin-sensitive obese adults.
Lipid mixtures containing a very high proportion of saturated fatty acids only modestly impair insulin signaling in cultured muscle cells.
Increased hepatic Fatty Acid uptake and esterification contribute to tetracycline-induced steatosis in mice.
The effect of high-intensity training on mitochondrial fat oxidation in skeletal muscle and subcutaneous adipose tissue.
Rapid development of systemic insulin resistance with overeating is not accompanied by robust changes in skeletal muscle glucose and lipid metabolism.
DGAT1 mutation is linked to a congenital diarrheal disorder.
High fatty acid availability after exercise alters the regulation of muscle lipid metabolism.
High muscle lipid content in obesity is not due to enhanced activation of key triglyceride esterification enzymes or the suppression of lipolytic proteins.
Harasim-Symbor E, Polak-Iwaniuk A, Konstantynowicz-Nowicka K, Bielawiec P, Malinowska B, Kasacka I, Chabowski A
Molecules (Basel, Switzerland) 2020 Apr 21;25(8)
Molecules (Basel, Switzerland) 2020 Apr 21;25(8)
Simvastatin-Induced Insulin Resistance May Be Linked to Decreased Lipid Uptake and Lipid Synthesis in Human Skeletal Muscle: the LIFESTAT Study.
Larsen S, Vigelsø A, Dandanell S, Prats C, Dela F, Helge JW
Journal of diabetes research 2018;2018:9257874
Journal of diabetes research 2018;2018:9257874
Fatty acid transport protein 1 regulates retinoid metabolism and photoreceptor development in mouse retina.
Cubizolle A, Guillou L, Mollereau B, Hamel CP, Brabet P
PloS one 2017;12(7):e0180148
PloS one 2017;12(7):e0180148
Factors regulating subcutaneous adipose tissue storage, fibrosis, and inflammation may underlie low fatty acid mobilization in insulin-sensitive obese adults.
Van Pelt DW, Guth LM, Wang AY, Horowitz JF
American journal of physiology. Endocrinology and metabolism 2017 Oct 1;313(4):E429-E439
American journal of physiology. Endocrinology and metabolism 2017 Oct 1;313(4):E429-E439
Lipid mixtures containing a very high proportion of saturated fatty acids only modestly impair insulin signaling in cultured muscle cells.
Newsom SA, Everett AC, Park S, Van Pelt DW, Hinko A, Horowitz JF
PloS one 2015;10(3):e0120871
PloS one 2015;10(3):e0120871
Increased hepatic Fatty Acid uptake and esterification contribute to tetracycline-induced steatosis in mice.
Choi YJ, Lee CH, Lee KY, Jung SH, Lee BH
Toxicological sciences : an official journal of the Society of Toxicology 2015 Jun;145(2):273-82
Toxicological sciences : an official journal of the Society of Toxicology 2015 Jun;145(2):273-82
The effect of high-intensity training on mitochondrial fat oxidation in skeletal muscle and subcutaneous adipose tissue.
Larsen S, Danielsen JH, Søndergård SD, Søgaard D, Vigelsoe A, Dybboe R, Skaaby S, Dela F, Helge JW
Scandinavian journal of medicine & science in sports 2015 Feb;25(1):e59-69
Scandinavian journal of medicine & science in sports 2015 Feb;25(1):e59-69
Rapid development of systemic insulin resistance with overeating is not accompanied by robust changes in skeletal muscle glucose and lipid metabolism.
Cornford AS, Hinko A, Nelson RK, Barkan AL, Horowitz JF
Applied physiology, nutrition, and metabolism = Physiologie appliquee, nutrition et metabolisme 2013 May;38(5):512-9
Applied physiology, nutrition, and metabolism = Physiologie appliquee, nutrition et metabolisme 2013 May;38(5):512-9
DGAT1 mutation is linked to a congenital diarrheal disorder.
Haas JT, Winter HS, Lim E, Kirby A, Blumenstiel B, DeFelice M, Gabriel S, Jalas C, Branski D, Grueter CA, Toporovski MS, Walther TC, Daly MJ, Farese RV Jr
The Journal of clinical investigation 2012 Dec;122(12):4680-4
The Journal of clinical investigation 2012 Dec;122(12):4680-4
High fatty acid availability after exercise alters the regulation of muscle lipid metabolism.
Newsom SA, Schenk S, Li M, Everett AC, Horowitz JF
Metabolism: clinical and experimental 2011 Jun;60(6):852-9
Metabolism: clinical and experimental 2011 Jun;60(6):852-9
High muscle lipid content in obesity is not due to enhanced activation of key triglyceride esterification enzymes or the suppression of lipolytic proteins.
Li M, Paran C, Wolins NE, Horowitz JF
American journal of physiology. Endocrinology and metabolism 2011 Apr;300(4):E699-707
American journal of physiology. Endocrinology and metabolism 2011 Apr;300(4):E699-707
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Supportive validation
- Submitted by
- Novus Biologicals (provider)
- Main image
- Experimental details
- Western Blot: DGAT1 Antibody [NB110-41487] - Detection of DGAT1 in HepG2 lysate.
- Submitted by
- Novus Biologicals (provider)
- Main image
- Experimental details
- Western Blot: DGAT1 Antibody [NB110-41487] - Factors regulating lipid storage and breakdown in C2C12 muscle cells.Muscle cells were incubated with PALM (open), NORM (filled), or HSFA (hatched). Pictured is protein abundance of DGAT1. In the figure panel, the data is expressed relative to a no fatty acid control condition (0mM). In panel B, #P