orb66898

antibody from Biorbyt
Targeting: AGER RAGE, SCARJ1
Provider product page for orb66898
Western blot

Antibody data

Product number
orb66898 - Provider product page
Provider
Biorbyt
Product name
AGER antibody
Antibody type
Polyclonal
Description
Rabbit polyclonal to AGER.Advanced glycosylation end product-specific receptor (AGER) is also known as receptor for advancedglycation end products AGE), a member of the immunoglobulin superfamily of cell surfacemolecules. AGER is expressed as full-length, membrane-bound RAGE isoform 1 or as a secretedprotein that lacks a transmembrane domain. The observed M.W. of AGER is 48-58 kD. It is a receptorfor a number of different molecules including the ambloidogenic form of serum amyloid A, amyloidbetaprotein, members of the S100/calgranulin superfamily and advanced glycation end products. Itacts as mediator of both acute and chronic vascular inflammation in conditions such asatherosclerosis and in particular as a complication of diabetes. Alternative splicing yields twotranscript variants encoding different isoforms.
Reactivity
Human, Mouse
Host
Rabbit
Conjugate
Unconjugated
Vial size
100 ul
Storage
-20°C
AGER protein structure - orb66898 shown in red.