Antibody data
- Antibody Data
- Antigen structure
- References [4]
- Comments [0]
- Validations
- Western blot [1]
- Immunohistochemistry [1]
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Validation data
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- Product number
- ABIN1108826 - Provider product page
- Provider
- antibodies-online
- Product name
- anti-Advanced Glycosylation End Product-Specific Receptor (AGER) (Middle Region) antibody
- Antibody type
- Polyclonal
- Description
- Immunoaffinity Chromatography
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Epitope
- Middle Region
- Isotype
- IgG
- Vial size
- 0.2 mL
- Storage
- Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
- Handling
- Avoid repeated freezing and thawing.
Submitted references Loss of pain perception in diabetes is dependent on a receptor of the immunoglobulin superfamily.
The pattern recognition receptor (RAGE) is a counterreceptor for leukocyte integrins: a novel pathway for inflammatory cell recruitment.
Blockade of RAGE-amphoterin signalling suppresses tumour growth and metastases.
RAGE mediates a novel proinflammatory axis: a central cell surface receptor for S100/calgranulin polypeptides.
Bierhaus A, Haslbeck KM, Humpert PM, Liliensiek B, Dehmer T, Morcos M, Sayed AA, Andrassy M, Schiekofer S, Schneider JG, Schulz JB, Heuss D, Neundörfer B, Dierl S, Huber J, Tritschler H, Schmidt AM, Schwaninger M, Haering HU, Schleicher E, Kasper M, Stern DM, Arnold B, Nawroth PP
The Journal of clinical investigation 2004 Dec;114(12):1741-51
The Journal of clinical investigation 2004 Dec;114(12):1741-51
The pattern recognition receptor (RAGE) is a counterreceptor for leukocyte integrins: a novel pathway for inflammatory cell recruitment.
Chavakis T, Bierhaus A, Al-Fakhri N, Schneider D, Witte S, Linn T, Nagashima M, Morser J, Arnold B, Preissner KT, Nawroth PP
The Journal of experimental medicine 2003 Nov 17;198(10):1507-15
The Journal of experimental medicine 2003 Nov 17;198(10):1507-15
Blockade of RAGE-amphoterin signalling suppresses tumour growth and metastases.
Taguchi A, Blood DC, del Toro G, Canet A, Lee DC, Qu W, Tanji N, Lu Y, Lalla E, Fu C, Hofmann MA, Kislinger T, Ingram M, Lu A, Tanaka H, Hori O, Ogawa S, Stern DM, Schmidt AM
Nature 2000 May 18;405(6784):354-60
Nature 2000 May 18;405(6784):354-60
RAGE mediates a novel proinflammatory axis: a central cell surface receptor for S100/calgranulin polypeptides.
Hofmann MA, Drury S, Fu C, Qu W, Taguchi A, Lu Y, Avila C, Kambham N, Bierhaus A, Nawroth P, Neurath MF, Slattery T, Beach D, McClary J, Nagashima M, Morser J, Stern D, Schmidt AM
Cell 1999 Jun 25;97(7):889-901
Cell 1999 Jun 25;97(7):889-901
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Supportive validation
- Submitted by
- antibodies-online (provider)
- Main image
- Experimental details
- WB
Supportive validation
- Submitted by
- antibodies-online (provider)
- Main image
- Experimental details
- IHC